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Sequences

Sequence NM_016452

ACTCAGCCCAGTGGCCCTCTGAGCTGTTCCTTCTTGACCGGCACACACAGCTCGCTTCTTCACTTTCTTTTCCATCCACTGCCGGACCCAAGCCAGCCTT CCAGGGAGCAGCCATGCCTTACCTCTACCGGGCCCCAGGGCCTCAGGCACACCCGGTTCCCAAGGACGCCCGGATCACCCACTCCTCAGGCCAGAGCTTT GAGCAAATGAGGCAGGAGTGCCTGCAGAGAGGCACCCTGTTTGAGGATGCAGACTTCCCAGCCAGCAATTCCTCCCTGTTCTACAGTGAGAGGCCGCAGA TCCCCTTTGTGTGGAAACGACCAGGGGAAATCGTGAAAAACCCAGAATTCATTCTTGGAGGGGCCACCAGGACTGATATCTGCCAGGGAGAGCTGGGAGA CTGCTGGCTATTAGCCGCCATCGCCTCCCTTACGCTTAATCAAAAAGCACTGGCCAGAGTCATCCCCCAGGACCAAAGCTTTGGCCCTGGTTATGCCGGG ATATTCCATTTCCAGTTCTGGCAGCACAGTGAGTGGCTGGACGTGGTGATCGATGACCGCCTGCCCACCTTCAGGGACCGCTTGGTTTTCCTCCACTCTG CCGACCACAACGAGTTCTGGAGCGCCTTGCTGGAAAAAGCCTACGCCAAGCTAAATGGGAGCTATGAAGCTCTGAAGGGAGGCAGCGCCATCGAGGCCAT GGAAGACTTCACTGGGGGTGTGGCAGAGACCTTCCAAACTAAAGAGGCCCCCGAGAACTTCTATGAGATTCTAGAGAAGGCTTTGAAGAGAGGCTCCCTG CTGGGCTGCTTCATTGATACCAGAAGTGCTGCAGAATCTGAGGCCCGGACGCCGTTTGGTCTTATTAAGGGTCATGCCTACAGTGTAACGGGAATTGACC AGGTAAGCTTCCGAGGCCAGAGAATCGAGCTCATCCGAATCCGGAACCCTTGGGGCCAGGTTGAGTGGAACGGGTCGTGGAGCGACAGGATGGCATTTAA GGACTTCAAGGCCCACTTTGATAAAGTGGAGATCTGCAACCTCACTCCCGATGCCCTGGAGGAAGACGCGATCCACAAATGGGAGGTGACGGTCCATCAG GGAAGCTGGGTTCGCGGCTCCACGGCTGGGGGCTGCCGCAATTTCCTGGATACCTTTTGGACCAATCCACAAATAAAATTGTCTCTGACTGAGAAAGATG AGGGGCAGGAGGAGTGTAGTTTCCTTGTAGCCCTGATGCAGAAAGATAGAAGGAAACTCAAGAGATTTGGTGCCAATGTGCTGACAATCGGCTATGCCAT TTATGAGTGCCCTGACAAAGACGAACACCTGAACAAAGACTTCTTCAGATACCACGCTTCTCGGGCCAGAAGCAAGACGTTCATCAACCTGAGAGAAGTC TCCGACCGGTTCAAGCTGCCCCCTGGGGAGTACATCCTGATTCCCAGCACTTTTGAGCCCCACCAGGAAGCTGATTTCTGTCTGAGAATCTTTTCAGAGA AAAAAGCCATTACCCGGGATATGGATGGAAATGTAGACATTGACCTTCCTGAGCCTCCAAAGCCAACTCCACCTGACCAGGAGACAGAGGAGGAGCAGCG GTTTCGGGCTCTGTTTGAACAAGTCGCTGGTGAGGACATGGAGGTGACAGCAGAGGAACTTGAGTATGTTTTAAATGCTGTGCTGCAAAAGAAAAAGGAC ATCAAATTCAAGAAGCTAAGCCTGATCTCCTGTAAAAACATCATTTCCCTGATGGACACCAGCGGCAATGGGAAGCTGGAGTTTGATGAATTCAAAGTGT TCTGGGACAAGCTGAAGCAGTGGATTAACCTTTTCCTTCGGTTTGATGCTGACAAGTCCGGCACCATGTCTACCTATGAACTACGGACTGCACTGAAAGC TGCAGGCTTTCAGCTGAGCAGCCACCTCCTGCAGCTGATTGTGCTCAGGTATGCGGATGAGGAGCTCCAGCTGGACTTCGATGACTTCCTCAACTGCCTG GTCCGGCTGGAGAATGCGAGCCGGGTGTTCCAGGCTCTCAGTACAAAGAACAAGGAGTTCATTCATCTCAATATAAATGAGTTCATCCATTTGACAATGA ACATCTGAGGCTGCCTTGTAGAGATGCAGCCTGCCCAGCTGAATCTTGGCTTCTGGACCTTGACCTTCAGAACTTCTCTTGGTGTGGAACCATTACGCCC AGGGTTCACTCCCCTCTCATCGTCCGGCCTTCTCCCTTCATCTTGATCTGGGAAGAATGAAATGAACTCAGCTACACTCTCTGATTTTGTGCTACTCCTT TGTAAAGTCACTGCCTTAAGGGGGCTGATGGCGCCACCTGTGCCTTACATCCAGGTTCAGGCATCACTAGCTTTCCCACACTCTACTTTCCTTATTTCCT TCCATTAAGAATTACTCAGAGTTCTAACGCACAGAATCCTGACTTCCATGTAGCTCCAGTCATTGTGATCAGACATCCTTTATAAAACATGTTTTTATAA ATGTGTATGTGGAAT

refseq_CAPN9.F1 (forward primer)
refseq_CAPN9.R1 (reverse primer)
Single exon skipping

Frame 0

TQPSGPLSCSFLTGTHSSLLHFLFHPLPDPSQP SREQPCLTSTGPQGLRHTRFPRTPGSPTPQARAL SK*GRSACREAPCLRMQTSQPAIPPCSTVRGRR SPLCGNDQGKS*KTQNSFLEGPPGLISARESWE TAGY*PPSPPLRLIKKHWPESSPRTKALALVMPG YSISSSGSTVSGWTW*SMTACPPSGTAWFSSTL PTTTSSGAPCWKKPTPS*MGAMKL*REAAPSRP WKTSLGVWQRPSKLKRPPRTSMRF*RRL*REAPC WAASLIPEVLQNLRPGRRLVLLRVMPTV*RELT R*ASEARESSSSESGTLGARLSGTGRGATGWHL RTSRPTLIKWRSATSLPMPWRKTRSTNGR*RSIR EAGFAAPRLGAAAISWIPFGPIHK*NCL*LRKM RGRRSVVSL*P*CRKIEGNSRDLVPMC*QSAMP FMSALTKTNT*TKTSSDTTLLGPEARRSST*EKS PTGSSCPLGSTS*FPALLSPTRKLISV*ESFQR KKPLPGIWMEM*TLTFLSLQSQLHLTRRQRRSS GFGLCLNKSLVRTWR*QQRNLSMF*MLCCKRKRT SNSRS*A*SPVKTSFP*WTPAAMGSWSLMNSKC SGTS*SSGLTFSFGLMLTSPAPCLPMNYGLH*K LQAFS*AATSCS*LCSGMRMRSSSWTSMTSSTAW SGWRMRAGCSRLSVQRTRSSFISI*MSSSI*Q* TSEAAL*RCSLPS*ILASGP*PSELLLVWNHYA QGSLPSHRPAFSLHLDLGRMK*TQLHSLILCYSF VKSLP*GG*WRHLCLTSRFRHH*LSHTLLSLFP SIKNYSEF*RTES*LPCSSSHCDQTSFIKHVFI NVYVE

Frame 1

LSPVAL*AVPS*PAHTARFFTFFSIHCRTQASL PGSSHALPLPGPRASGTPGSQGRPDHPLLRPEL *ANEAGVPAERHPV*GCRLPSQQFLPVLQ*EAAD PLCVETTRGNREKPRIHSWRGHQD*YLPGRAGR LLAISRHRLPYA*SKSTGQSHPPGPKLWPWLCR DIPFPVLAAQ*VAGRGDR*PPAHLQGPLGFPPLC RPQRVLERLAGKSLRQAKWEL*SSEGRQRHRGH GRLHWGCGRDLPN*RGPRELL*DSREGFEERLP AGLLH*YQKCCRI*GPDAVWSY*GSCLQCNGN*P GKLPRPENRAHPNPEPLGPG*VERVVERQDGI* GLQGPL**SGDLQPHSRCPGGRRDPQMGGDGPS GKLGSRLHGWGLPQFPGYLLDQSTNKIVSD*ER* GAGGV*FPCSPDAER*KETQEIWCQCADNRLCH L*VP*QRRTPEQRLLQIPRFSGQKQDVHQPERS LRPVQAAPWGVHPDSQHF*APPGS*FLSENLFRE KSHYPGYGWKCRH*PS*ASKANST*PGDRGGAA VSGSV*TSRW*GHGGDSRGT*VCFKCCAAKEKG HQIQEAKPDLL*KHHFPDGHQRQWEAGV**IQSV LGQAEAVD*PFPSV*C*QVRHHVYL*TTDCTES CRLSAEQPPPAADCAQVCG*GAPAGLR*LPQLP GPAGECEPGVPGSQYKEQGVHSSQYK*VHPFDNE HLRLPCRDAACPAESWLLDLDLQNFSWCGTITP RVHSPLIVRPSPFILIWEE*NELSYTL*FCATP L*SHCLKGADGATCALHPGSGITSFPTLYFPYFL PLRITQSSNAQNPDFHVAPVIVIRHPL*NMFL* MCMWN

Frame 2

SAQWPSELFLLDRHTQLASSLSFPSTAGPKPAF QGAAMPYLYRAPGPQAHPVPKDARITHSSGQSF EQMRQECLQRGTLFEDADFPASNSSLFYSERPQ IPFVWKRPGEIVKNPEFILGGATRTDICQGELGD CWLLAAIASLTLNQKALARVIPQDQSFGPGYAG IFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHS ADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAM EDFTGGVAETFQTKEAPENFYEILEKALKRGSL LGCFIDTRSAAESEARTPFGLIKGHAYSVTGID QVSFRGQRIELIRIRNPWGQVEWNGSWSDRMAFK DFKAHFDKVEICNLTPDALEEDAIHKWEVTVHQ GSWVRGSTAGGCRNFLDTFWTNPQIKLSLTEKD EGQEECSFLVALMQKDRRKLKRFGANVLTIGYAI YECPDKDEHLNKDFFRYHASRARSKTFINLREV SDRFKLPPGEYILIPSTFEPHQEADFCLRIFSE KKAITRDMDGNVDIDLPEPPKPTPPDQETEEEQR FRALFEQVAGEDMEVTAEELEYVLNAVLQKKKD IKFKKLSLISCKNIISLMDTSGNGKLEFDEFKV FWDKLKQWINLFLRFDADKSGTMSTYELRTALKA AGFQLSSHLLQLIVLRYADEELQLDFDDFLNCL VRLENASRVFQALSTKNKEFIHLNINEFIHLTM NI*GCLVEMQPAQLNLGFWTLTFRTSLGVEPLRP GFTPLSSSGLLPSS*SGKNEMNSATLSDFVLLL CKVTALRGLMAPPVPYIQVQASLAFPHSTFLIS FH*ELLRVLTHRILTSM*LQSL*SDILYKTCFYK CVCG

Sequence NM_006615

ACTCAGCCCAGTGGCCCTCTGAGCTGTTCCTTCTTGACCGGCACACACAGCTCGCTTCTTCACTTTCTTTTCCATCCACTGCCGGACCCAAGCCAGCCTT CCAGGGAGCAGCCATGCCTTACCTCTACCGGGCCCCAGGGCCTCAGGCACACCCGGTTCCCAAGGACGCCCGGATCACCCACTCCTCAGGCCAGAGCTTT GAGCAAATGAGGCAGGAGTGCCTGCAGAGAGGCACCCTGTTTGAGGATGCAGACTTCCCAGCCAGCAATTCCTCCCTGTTCTACAGTGAGAGGCCGCAGA TCCCCTTTGTGTGGAAACGACCAGGGGAAATCGTGAAAAACCCAGAATTCATTCTTGGAGGGGCCACCAGGACTGATATCTGCCAGGGAGAGCTGGGAGA CTGCTGGCTATTAGCCGCCATCGCCTCCCTTACGCTTAATCAAAAAGCACTGGCCAGAGTCATCCCCCAGGACCAAAGCTTTGGCCCTGGTTATGCCGGG ATATTCCATTTCCAGTTCTGGCAGCACAGTGAGTGGCTGGACGTGGTGATCGATGACCGCCTGCCCACCTTCAGGGACCGCTTGGTTTTCCTCCACTCTG CCGACCACAACGAGTTCTGGAGCGCCTTGCTGGAAAAAGCCTACGCCAAGCTAAATGGGAGCTATGAAGCTCTGAAGGGAGGCAGCGCCATCGAGGCCAT GGAAGACTTCACTGGGGGTGTGGCAGAGACCTTCCAAACTAAAGAGGCCCCCGAGAACTTCTATGAGATTCTAGAGAAGGCTTTGAAGAGAGGCTCCCTG CTGGGCTGCTTCATTGATACCAGAAGTGCTGCAGAATCTGAGGCCCGGACGCCGTTTGGTCTTATTAAGGGTCATGCCTACAGTGTAACGGGAATTGACC AGGTAAGCTTCCGAGGCCAGAGAATCGAGCTCATCCGAATCCGGAACCCTTGGGGCCAGGTTGAGTGGAACGGGTCGTGGAGCGACAGTTCTCCGGAGTG GCGTTCTGTTGGTCCAGCTGAGCAGAAGCGTCTGTGTCACACTGCTCTGGATGATGGGGAATTCTGGATGGCATTTAAGGACTTCAAGGCCCACTTTGAT AAAGTGGAGATCTGCAACCTCACTCCCGATGCCCTGGAGGAAGACGCGATCCACAAATGGGAGGTGACGGTCCATCAGGGAAGCTGGGTTCGCGGCTCCA CGGCTGGGGGCTGCCGCAATTTCCTGGATACCTTTTGGACCAATCCACAAATAAAATTGTCTCTGACTGAGAAAGATGAGGGGCAGGAGGAGTGTAGTTT CCTTGTAGCCCTGATGCAGAAAGATAGAAGGAAACTCAAGAGATTTGGTGCCAATGTGCTGACAATCGGCTATGCCATTTATGAGTGCCCTGACAAAGAC GAACACCTGAACAAAGACTTCTTCAGATACCACGCTTCTCGGGCCAGAAGCAAGACGTTCATCAACCTGAGAGAAGTCTCCGACCGGTTCAAGCTGCCCC CTGGGGAGTACATCCTGATTCCCAGCACTTTTGAGCCCCACCAGGAAGCTGATTTCTGTCTGAGAATCTTTTCAGAGAAAAAAGCCATTACCCGGGATAT GGATGGAAATGTAGACATTGACCTTCCTGAGCCTCCAAAGCCAACTCCACCTGACCAGGAGACAGAGGAGGAGCAGCGGTTTCGGGCTCTGTTTGAACAA GTCGCTGGTGAGGACATGGAGGTGACAGCAGAGGAACTTGAGTATGTTTTAAATGCTGTGCTGCAAAAGAAAAAGGACATCAAATTCAAGAAGCTAAGCC TGATCTCCTGTAAAAACATCATTTCCCTGATGGACACCAGCGGCAATGGGAAGCTGGAGTTTGATGAATTCAAAGTGTTCTGGGACAAGCTGAAGCAGTG GATTAACCTTTTCCTTCGGTTTGATGCTGACAAGTCCGGCACCATGTCTACCTATGAACTACGGACTGCACTGAAAGCTGCAGGCTTTCAGCTGAGCAGC CACCTCCTGCAGCTGATTGTGCTCAGGTATGCGGATGAGGAGCTCCAGCTGGACTTCGATGACTTCCTCAACTGCCTGGTCCGGCTGGAGAATGCGAGCC GGGTGTTCCAGGCTCTCAGTACAAAGAACAAGGAGTTCATTCATCTCAATATAAATGAGTTCATCCATTTGACAATGAACATCTGAGGCTGCCTTGTAGA GATGCAGCCTGCCCAGCTGAATCTTGGCTTCTGGACCTTGACCTTCAGAACTTCTCTTGGTGTGGAACCATTACGCCCAGGGTTCACTCCCCTCTCATCG TCCGGCCTTCTCCCTTCATCTTGATCTGGGAAGAATGAAATGAACTCAGCTACACTCTCTGATTTTGTGCTACTCCTTTGTAAAGTCACTGCCTTAAGGG GGCTGATGGCGCCACCTGTGCCTTACATCCAGGTTCAGGCATCACTAGCTTTCCCACACTCTACTTTCCTTATTTCCTTCCATTAAGAATTACTCAGAGT TCTAACGCACAGAATCCTGACTTCCATGTAGCTCCAGTCATTGTGATCAGACATCCTTTATAAAACATGTTTTTATAAATGTGTATGTGGAAT

refseq_CAPN9.F1 (forward primer)
refseq_CAPN9.R1 (reverse primer)
Single exon skipping

Frame 0

TQPSGPLSCSFLTGTHSSLLHFLFHPLPDPSQP SREQPCLTSTGPQGLRHTRFPRTPGSPTPQARAL SK*GRSACREAPCLRMQTSQPAIPPCSTVRGRR SPLCGNDQGKS*KTQNSFLEGPPGLISARESWE TAGY*PPSPPLRLIKKHWPESSPRTKALALVMPG YSISSSGSTVSGWTW*SMTACPPSGTAWFSSTL PTTTSSGAPCWKKPTPS*MGAMKL*REAAPSRP WKTSLGVWQRPSKLKRPPRTSMRF*RRL*REAPC WAASLIPEVLQNLRPGRRLVLLRVMPTV*RELT R*ASEARESSSSESGTLGARLSGTGRGATVLRS GVLLVQLSRSVCVTLLWMMGNSGWHLRTSRPTLI KWRSATSLPMPWRKTRSTNGR*RSIREAGFAAP RLGAAAISWIPFGPIHK*NCL*LRKMRGRRSVV SL*P*CRKIEGNSRDLVPMC*QSAMPFMSALTKT NT*TKTSSDTTLLGPEARRSST*EKSPTGSSCP LGSTS*FPALLSPTRKLISV*ESFQRKKPLPGI WMEM*TLTFLSLQSQLHLTRRQRRSSGFGLCLNK SLVRTWR*QQRNLSMF*MLCCKRKRTSNSRS*A *SPVKTSFP*WTPAAMGSWSLMNSKCSGTS*SS GLTFSFGLMLTSPAPCLPMNYGLH*KLQAFS*AA TSCS*LCSGMRMRSSSWTSMTSSTAWSGWRMRA GCSRLSVQRTRSSFISI*MSSSI*Q*TSEAAL* RCSLPS*ILASGP*PSELLLVWNHYAQGSLPSHR PAFSLHLDLGRMK*TQLHSLILCYSFVKSLP*G G*WRHLCLTSRFRHH*LSHTLLSLFPSIKNYSE F*RTES*LPCSSSHCDQTSFIKHVFINVYVE

Frame 1

LSPVAL*AVPS*PAHTARFFTFFSIHCRTQASL PGSSHALPLPGPRASGTPGSQGRPDHPLLRPEL *ANEAGVPAERHPV*GCRLPSQQFLPVLQ*EAAD PLCVETTRGNREKPRIHSWRGHQD*YLPGRAGR LLAISRHRLPYA*SKSTGQSHPPGPKLWPWLCR DIPFPVLAAQ*VAGRGDR*PPAHLQGPLGFPPLC RPQRVLERLAGKSLRQAKWEL*SSEGRQRHRGH GRLHWGCGRDLPN*RGPRELL*DSREGFEERLP AGLLH*YQKCCRI*GPDAVWSY*GSCLQCNGN*P GKLPRPENRAHPNPEPLGPG*VERVVERQFSGV AFCWSS*AEASVSHCSG*WGILDGI*GLQGPL* *SGDLQPHSRCPGGRRDPQMGGDGPSGKLGSRLH GWGLPQFPGYLLDQSTNKIVSD*ER*GAGGV*F PCSPDAER*KETQEIWCQCADNRLCHL*VP*QR RTPEQRLLQIPRFSGQKQDVHQPERSLRPVQAAP WGVHPDSQHF*APPGS*FLSENLFREKSHYPGY GWKCRH*PS*ASKANST*PGDRGGAAVSGSV*T SRW*GHGGDSRGT*VCFKCCAAKEKGHQIQEAKP DLL*KHHFPDGHQRQWEAGV**IQSVLGQAEAV D*PFPSV*C*QVRHHVYL*TTDCTESCRLSAEQ PPPAADCAQVCG*GAPAGLR*LPQLPGPAGECEP GVPGSQYKEQGVHSSQYK*VHPFDNEHLRLPCR DAACPAESWLLDLDLQNFSWCGTITPRVHSPLI VRPSPFILIWEE*NELSYTL*FCATPL*SHCLKG ADGATCALHPGSGITSFPTLYFPYFLPLRITQS SNAQNPDFHVAPVIVIRHPL*NMFL*MCMWN

Frame 2

SAQWPSELFLLDRHTQLASSLSFPSTAGPKPAF QGAAMPYLYRAPGPQAHPVPKDARITHSSGQSF EQMRQECLQRGTLFEDADFPASNSSLFYSERPQ IPFVWKRPGEIVKNPEFILGGATRTDICQGELGD CWLLAAIASLTLNQKALARVIPQDQSFGPGYAG IFHFQFWQHSEWLDVVIDDRLPTFRDRLVFLHS ADHNEFWSALLEKAYAKLNGSYEALKGGSAIEAM EDFTGGVAETFQTKEAPENFYEILEKALKRGSL LGCFIDTRSAAESEARTPFGLIKGHAYSVTGID QVSFRGQRIELIRIRNPWGQVEWNGSWSDSSPEW RSVGPAEQKRLCHTALDDGEFWMAFKDFKAHFD KVEICNLTPDALEEDAIHKWEVTVHQGSWVRGS TAGGCRNFLDTFWTNPQIKLSLTEKDEGQEECSF LVALMQKDRRKLKRFGANVLTIGYAIYECPDKD EHLNKDFFRYHASRARSKTFINLREVSDRFKLP PGEYILIPSTFEPHQEADFCLRIFSEKKAITRDM DGNVDIDLPEPPKPTPPDQETEEEQRFRALFEQ VAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLS LISCKNIISLMDTSGNGKLEFDEFKVFWDKLKQW INLFLRFDADKSGTMSTYELRTALKAAGFQLSS HLLQLIVLRYADEELQLDFDDFLNCLVRLENAS RVFQALSTKNKEFIHLNINEFIHLTMNI*GCLVE MQPAQLNLGFWTLTFRTSLGVEPLRPGFTPLSS SGLLPSS*SGKNEMNSATLSDFVLLLCKVTALR GLMAPPVPYIQVQASLAFPHSTFLISFH*ELLRV LTHRILTSM*LQSL*SDILYKTCFYKCVCG