Sequences - Rnomics 📊 Palace

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        Rnomics 📊 Palace
    
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Sequences

Sequence NM_052900

GAGACTTTGTGCCCCCGTTGGAGAGATGGTTGAGTCCTCGTCAAGGTTGCTGTGGTATCCCAGAAACACCATTCACTCCGAGCTGTGACCGCGCACCAAC AACAGCAACAACTCCACTGCGCCGGGCTGAGGAGCAGGAATTAGGAGCTCGCGAATAATATGAAAGGGATCCGCAAAGGGGAAAGCCGAGCAAAGGAATC CAAACCCTGGGAGCCTGGCAAGCGAAGATGCGCTAAATGTGGCCGCCTAGACTTCATCCTGATGAAGAAAATGGGGATTAAAAGTGGATTTACGTTTTGG AACCTCGTCTTTTTATTGACGGTGTCTTGTGTGAAAGGATTTATTTATACATGTGGTGGAACTTTAAAAGGACTTAATGGCACTATAGAAAGCCCTGGTT TTCCATATGGATATCCAAATGGTGCAAACTGCACATGGGTAATAATAGCAGAAGAACGAAATAGAATACAAATTGTTTTTCAGTCATTTGCTCTAGAAGA AGAATACGACTACTTATCATTATATGATGGACATCCTCATCCTACAAACTTTAGGACAAGGTTAACAGGATTCCATCTGCCACCTCCAGTGACAAGTACC AAATCTGTGTTCTCACTACGTTTGACCAGTGATTTTGCAGTTAGTGCTCATGGATTTAAGGTATATTACGAAGAATTGCAGAGTAGCTCTTGTGGAAATC CTGGTGTTCCACCCAAAGGTGTATTATATGGCACAAGATTCGACGTCGGGGACAAGATCCGCTACAGCTGTGTAACTGGATACATCCTTGATGGCCACCC TCAGCTCACCTGCATAGCCAATTCAGTTAATACAGCTTCGTGGGATTTTCCTGTTCCTATCTGTAGAGCTGAAGATGCTTGTGGAGGAACAATGAGAGGA TCCAGTGGCATCATATCCAGCCCTAGTTTTCCTAATGAGTACCATAACAATGCTGATTGCACTTGGACCATTGTAGCAGAGCCTGGGGACACAATTTCAC TCATATTTACTGATTTTCAAATGGAAGAGAAATATGATTACTTAGAAATAGAAGGTTCTGAGCCACCTACCATATGGTTATCTGGAATGAATATACCACC ACCAATTATCAGCAACAAAAACTGGCTCAGACTGCATTTTGTTACAGACAGCAATCATCGATACCGTGGATTTAGTGCTCCCTATCAAGTGAAAAAGGCC ATAGATTTTAAATCTAGAGGATTTAAATTGTTTCCAGGGAAAGACAACAGCAACAAGTTTTCTATCTTAAATGAGGGAGGTATTAAAACAGCTTCCAATT TATGCCCAGATCCAGGAGAACCAGAAAATGGGAAGAGAATCGGATCAGATTTTAGCCTTGGATCAACTGTGCAGTTCTCTTGTGATGAAGATTATGTCCT ACAGGGCGCAAAGAGCATCACCTGTCAACGGATAGCTGAAGTTTTTGCTGCTTGGAGTGATCACAGGCCTGTGTGTAAAGTGAAAACGTGTGGCTCTAAT CTTCAAGGACCAAGTGGTACCTTTACATCTCCCAACTTTCCGTTCCAGTATGACAGCAATGCACAATGTGTCTGGGTCATCACAGCAGTGAATACAAATA AGGTTATCCAGATAAATTTTGAAGAATTTGATCTGGAGATTGGCTATGATACCTTGACAATTGGCGATGGGGGCGAAGTTGGAGATCCTAGGACAGTGCT CCAAGTGCTGACTGGAAGCTTTGTACCAGACTTGATAGTGAGCATGAGTAGCCAAATGTGGCTGCACCTTCAAACGGACGAAAGTGTTGGATCTGTTGGT TTCAAGGTTAACTACAAAGAAATTGAGAAAGAAAGTTGTGGTGATCCTGGTACACCCTTATATGGAATTAGAGAAGGCGATGGATTTTCTAATCGTGATG TTTTAAGGTTTGAATGCCAGTTTGGGTTTGAATTAATTGGAGAGAAATCCATTGTTTGTCAAGAGAATAACCAATGGTCTGCAAACATACCCATCTGTAT CTTTCCCTGCCTGTCTAACTTTACTGCACCAATGGGAACAGTTCTTTCTCCTGATTACCCAGAAGGGTATGGAAATAATTTAAATTGCATCTGGACGATA ATCTCTGATCCAGGGAGCCGGATACATCTTTCTTTCAATGACTTTGACCTGGAATCCCAGTTTGATTTCCTTGCTGTTAAAGATGGTGACTCTCCAGAAT CCCCAATTCTTGGAACCTTTACTGGGGCTGAGGTGCCTTCCCATCTTACTAGTAATAGTCACATACTGCGATTGGAATTTCAGGCTGACCACTCAATGTC AGGACGTGGCTTTAACATCACTTACAACACATTTGGACATAATGAATGCCCTGATCCTGGAATACCAATCAATGCACGGCGGTTTGGGGACAACTTTCAA TTAGGAAGTTCAATTTCAGTTATTTGTGAAGAAGGATTTATTAAAACCCAGGGAACAGAAACAATTACATGTATTCTTATGGATGGAAAAGTAATGTGGA GTGGACTGATTCCAAAATGTGGAGCCCCATGTGGTGGCCATTTTTCAGCTCCCAGTGGAGTGATTCTCTCACCAGGATGGCCAGGATACTACAAAGACTC TTTGAATTGTGAGTGGGTGATTGAAGCTGAACCTGGACACTCTATCAAAATTACATTTGAAAGATTTCAGACTGAACTGAATTATGATGTTCTGGAAGTT CATGATGGGCCAAATCTTCTGTCACCCTTGCTTGGATCTTACAATGGCACCCAAGTGCCCCAGTTTCTATTTAGTAGCAGTAATTTTATATACCTTCTAT TTACAACAGACAACAGTCGTTCCAATAATGGTTTCAAGATTCATTATGAAAGTGTTACAGTGAACACGTATTCTTGTTTGGACCCTGGCATACCTGTACA TGGCCGTCGCTATGGTCATGATTTCTCCATTGGCTCTACTGTTTCATTTAGTTGTGATTCAGGATACAGGTTGAGTCATGAAGAGCCCCTTCTATGCGAA AAAAACCACTGGTGGAGTCATCCACTTCCAACCTGTGATGCATTATGTGGAGGAGATGTTAGAGGGCCTAGTGGAACAATCTTATCACCTGGTTACCCGG AATTTTATCCAAATTCTCTGAATTGTACATGGACTGTTGATGTAACCCATGGAAAAGGTGTGCAGTTCAACTTCCACACTTTTCATTTGGAAGACCATCA TGACTACTTACTGATCACAGAGAATGGCAGTTTTACCCAACCACTGGCACGCCTGACTGGTTCAGATCTTCCTCCAACAATCAATGCTGGTCTCTATGGA AATTTCAGGGCTCAATTGCGTTTCATTTCAGATTTTTCAATATCATATGAAGGATTTAACATAACATTCTCTGAATATAACCTTGAACCTTGTGAAGATC CTGGCATTCCTCAATATGGTAGTCGAATCGGGTTCAACTTTGGGATTGGTGACACTCTGACCTTCTCATGCTCTTCGGGTTATCGACTGGAAGGAACATC AGAGATCATCTGTCTTGGTGGTGGCCGACGAGTGTGGAGTGCACCTCTGCCAAGGTGTGTGGCTGAATGTGGTGCATCTGCAACGAATAATGAAGGAATT TTGCTGTCTCCAAATTATCCACTCAACTATGAAAACAACCATGAATGCATTTATAGTATTCAGGTTCAAGCAGGAAAGGGAATCAATATTTCAGCCAGAA CATTTCATTTAGCACAAGGAGATGTTCTTAAGATTTATGATGGAAAAGATAAAACGACTCATCTACTAGGTGCTTTTACTGGTGCATCTATGCGCGGACT GACACTTAGTAGTACTTCAAATCAACTCTGGCTAGAATTTAATTCCGATACTGAAGGGACAGATGAAGGCTTTCAACTTGTGTATACCAGTTTTGAACTC TCACACTGTGAAGATCCTGGCATTCCACAATTTGGATACAAGATCAGTGACCAAGGCCACTTTGCTGGTAGCACCATCATTTATGGATGCAATCCAGGCT ACACTCTCCACGGAAGTAGCCTTCTCAAGTGCATGACAGGGGAGAGAAGGGCATGGGACTATCCTCTGCCTTCCTGTATTGCTGAATGTGGAGGTCGTTT TAAAGGAGAATCATCAGGAAGAATCTTATCTCCTGGCTATCCTTTTCCATATGACAATAACCTGCGTTGCATGTGGATGATTGAGGTAGATCCTGGAAAT ATTGTCAGCTTGCAGTTTCTTGCTTTTGATACGGAAGCATCACATGATATACTCCGAGTCTGGGACGGTCCACCAGAAAATGATATGCTTTTAAAGGAAA TTAGTGGATCTCTTATTCCTGAAGGAATTCATAGCACCCTCAATATAGTAACCATCCAGTTTGACACGGATTTTTATATTAGCAAATCTGGATTTGCAAT TCAGTTTTCAAGTTCTGTTGCCACTGCGTGTCGTGACCCAGGGGTCCCCATGAATGGGACTCGAAATGGGGATGGAAGAGAACCTGGGGACACTGTTGTT TTTCAATGTGACCCAGGATATGAACTTCAAGGAGAGGAAAGAATAACCTGCATTCAGGTAGAAAATCGGTACTTCTGGCAGCCCAGCCCACCAGTCTGTA TAGCACCCTGTGGAGGCAATTTAACAGGATCTTCAGGCTTTATTCTTTCACCAAACTTCCCTCATCCATATCCGCATAGCAGAGACTGTGACTGGACTAT CACCGTCAATGCAGACTATGTTATCTCCTTGGCGTTCATCAGTTTTAGCATAGAACCAAACTATGACTTCCTCTATATCTATGATGGACCAGACAGTAAT AGCCCACTGATTGGAAGTTTTCAAGACAGCAAGTTACCAGAGAGAATAGAAAGCAGCTCAAATACAATGCATTTGGCTTTTCGGAGTGATGGATCTGTTA GTTACACTGGATTTCATCTAGAATACAAAGCAAAACTGCGAGAGTCCTGCTTTGATCCAGGCAATATAATGAATGGCACCAGACTTGGAATGGATTATAA ATTAGGGTCAACAGTCACCTATTACTGTGATGCTGGTTATGTTCTTCAAGGTTATTCAACACTCACCTGTATCATGGGAGATGATGGAAGACCTGGATGG AATAGAGCCTTGCCAAGTTGTCATGCGCCCTGTGGAAGTCGTTCAACAGGTTCAGAAGGCACTGTTCTATCACCAAACTATCCAAAAAATTACAGTGTGG GACATAATTGTGTTTATTCTATAGCAGTTCCAAAGGAGTTTGTGGTGTTTGGCCAGTTTGTATTTTTCCAGACATCACTCCACGATGTTGTTGAGGTGTA TGATGGGCCAACTCAGCAATCTTCTCTGTTATCTTCCCTCTCAGGATCCCATTCAGGAGAATCACTTCCACTGAGTTCAGGTAATCAGATCACAATTCGA TTTACTTCAGTTGGACCAATAACAGCTAAGGGATTTCACTTTGTTTACCAAGCTGTTCCTAGAACAAGTTCTACACAATGCAGTTCTGTGCCTGAACCAA GATTCGGAAGAAGAATTGGCAATGAATTTGCAGTCGGTTCATCGGTTCTTTTTGATTGTAATCCAGGATATATTCTCCATGGATCCATAGCAATTAGGTG TGAAACAGTGCCCAATTCTTTGGCCCAGTGGAATGATTCCTTACCTACTTGTATTGTGCCCTGTGGTGGAATTTTAACTAAGCGCAAAGGGACTATTTTG TCACCTGGATACCCTGAGCCTTATGACAACAATCTGAATTGTGTGTGGAAGATCACAGTGCCAGAGGGAGCTGGCATTCAAGTGCAAGTTGTTAGCTTTG CTACAGAACATAATTGGGATTCTCTGGACTTTTATGATGGGGGAGACAACAATGCTCCAAGACTTGGAAGCTATTCAGGAACAACAATACCCCATCTTTT GAATAGTACGTCTAATAATCTGTATCTAAATTTTCAATCAGACATCAGTGTTTCTGCTGCAGGATTTCATCTTGAATACACAGCAATTGGTTTGGATTCC TGTCCTGAACCACAAACTCCTAGCAGTGGAATTAAAATTGGAGACAGATATATGGTTGGAGATGTAGTATCCTTTCAGTGTGATCAAGGATATTCTCTTC AGGGTCACTCTCACATTACATGTATGCCAGGACCTGTAAGAAGATGGAATTATCCAATCCCAATTTGTTTAGCTCAGTGTGGTGGTGCTATGTCAGACTT CAGTGGTGTGATCCTCAGTCCTGGGTTTCCTGGAAACTATCCCAGCAGTTTAGATTGCACATGGACAATAAATCTACCCATAGGTTTTGGTGTACATCTC CAGTTTGTAAATTTTTCTACAGAAACCATACATGATTATTTGGAAGTACGAAGTGGATCCTCAGAAACTAGTACTGTTATTGGCCGGCTTAGTGGTCCTC AAATACCATCTTCCTTATTCAGCACCACCCATGAAACCAGCTTATATTTTCACAGTGACTATTCACAAAACAAACAAGGGTTTCATATTGTATACCAAGC CTATCAGTTGCAAAGCTGTCCTGATCCACGCCCGTTTCGAAATGGTTTTGTAATTGGTAATGATTTTACTGTGGGTCAAACCATTTCATTTGAATGTTTC CCAGGATACACATTAATTGGAAATTCAGCTCTCACATGCCTTCACGGAGTCAGTCGTAATTGGAATCATCCACTTCCAAGGTGTGAAGCTCTTTGTGGTG GGAATATAACTGCAATGAATGGCACCATTTATTCTCCTGGGTATCCTGATGAATATCCAAACTTTCAAGATTGTTTTTGGCTTGTAAGAGTACCCCCTGG GAATGGCATCTACATCAATTTTACTGTCCTTCAAACAGAACCAATATATGATTTCATTACTGTATGGGATGGACCAGACCAAAATTCACCTCAGATCGGT CAGTTCAGTGGCAATACCGCTTTGGAATCAGTCTACAGTACTTCAAATCAGATTCTAATCAAATTCCACAGTGATTTCACAACAAGTGGCTTTTTTGTGC TCAGTTATCACGCCTATCAACTAAGGGTGTGCCAACCTCCACCACCTGTGCCCAATGCTGAAATTTTGACGGAAGATGATGAATTTGAAATAGGTGATAT TATTAGGTATCAGTGTCTTCCAGGATTTACTTTAGTTGGTAATGCAATTCTGACGTGCAGATTAGGAGAACGACTGCAGATGGATGGAGCACCTCCAGTT TGTCAAGTGCTCTGTCCTGCCAATGAATTACGGCTAGATTCTACTGGAGTCATATTGAGCCCTGGATATCCTGACAGTTACCCAAATCTTCAAATGTGTG CATGGAGCATTTCAGTGGAAAAGGGTTATAATATCACCATGTTTGTAGAATTCTTCCAGACAGAAAAGGAATTTGATGTTCTTCAGGTGTATGATGGACC AAATATTCAAAGTCCAGTGCTTATTTCCCTCAGTGGGGATTATTCATCTGCTTTTAATATAACAAGCAATGGTCATGAAGTATTTCTTCAGTGGTCAGCA GATCATGGCAATAACAAAAAAGGCTTCCGGATAAGATATATAGCTTTCTACTGTAGTACACCAGAATCCCCACCTCATGGATATATTATCAGTCAGACAG GTGGGCAGCTTAACAGTGTGGTCCGTTGGGCCTGTGATCGAGGATTCCGACTTGTTGGAAAAAGCAGTGCTGTGTGCAGAAAGTCTTCCTATGGGTATCA TGCATGGGATGCGCCAGTCCCTGCCTGTCAAGCAATTTCCTGTGGGATTCCTAAAGCTCCAACAAATGGAGGAATACTAACAACAGACTATTTGGTAGGA ACGCGAGTTACCTATTTTTGTAATGATGGATATCGATTGTCATCCAAAGAACTCACTACAGCTGTATGCCAATCAGATGGAACATGGAGCAATCATAACA AGACCCCTCGCTGTGTTGTTATTTCCTGTGGAGAACTACCTACACCTCCAAATGGAAATAAGATTGGAACTCAAACTTCATATGGCTCAACAGCTATCTT TACCTGCGACTTGGGATTCATGCTTGTGGGCTCTGCTGTAAGGGAATGCCTTTCCTCAGGTCTTTGGAGTGAATCTGAAACCAGATGCCTAGCGGGTCAT TGTGGAATTCCAGAACTGATTGTGAATGGTCAAGTCATTGGAGAAAATTATGGATATAGAGACACAGTTGTATATCAATGTAATCCTGGTTTTCGATTGA TTGGTTCTTCAGTGAGGATATGTCAACAGGATCACAATTGGTCTGGTCAGCTCCCATCCTGTGTGCCTGTTAGCTGTGGTCACCCTGGTAGTCCAATTTA TGGAAGAACAAGTGGAAATGGGTTCAACTTTAATGATGTGGTAACATTCTCATGCAATATTGGGTATCTTATGCAAGGGCCAACAAAGGCACAGTGCCAG GCCAACAGACAGTGGAGCCATCCTCCACCTATGTGCAAAGTGGTCAACTGTTCTGATCCTGGAATTCCAGCCAATTCTAAAAGAGAAAGTAAAATAGAAC ATGGAAATTTTACTTACGGCACTGTGGTATTCTATGACTGCAATCCTGGATATTTTTTATTTGGATCTTCAGTTTTGATATGTCAACCAAATGGACAATG GGACAAACCTTTACCAGAATGTATCATGATTGACTGTGGACACCCTGGCGTTCCTCCTAATGCAGTCCTGTCTGGCGAGAAGTATACTTTTGGGTCTACT GTTCACTATTCCTGCACAGGAAAGCGTTCCCTTTTAGGCCAGTCATCAAGAACCTGCCAATTGAATGGCCATTGGAGTGGATCACAACCTCATTGTTCAG GTGATGCTACTGGGACATGTGGCGATCCAGGTACTCCCGGCCATGGCTCTAGACAGGAAAGCAATTTCAGAACTAAAAGTACTGTACGTTATGCTTGTGA TACTGGTTACATCCTTCATGGCTCAGAAGAAAGAACATGTTTAGCTAATGGCAGTTGGACCGGAAGGCAGCCAGAGTGCAAAGCTGTGCAGTGTGGTAAC CCAGGAACCACAGCCAATGGGAAAGTCTTCCGAATTGATGGCACAACATTTTCTAGTTCAGTCATTTATTCCTGCATGGAGGGATACATCCTTTCTGGAC CTTCAGTTAGACAGTGCACAGCCAATGGAACATGGTCTGGAACTTTACCTAACTGTACAATAATCAGTTGTGGAGACCCAGGTATACCAGCCAATGGACT GAGATATGGAGATGATTATGTGGTTGGACAAAATGTTTCTTACATGTGCCAGCCAGGCTACACGATGGAATTGAATGGCTCCAGAATCAGGACTTGTACA ATTAATGGCACATGGAGTGGAGTAATGCCAACTTGTAGAGCTGTTACCTGCCCAACTCCTCCCCAGATCTCTAATGGAAGGCTGGAAGGAACAAATTTCG ACTGGGGCTTTAGTATTAGCTACATCTGTTCTCCAGGCTATGAGCTATCCTTCCCTGCTGTTTTGACCTGTGTAGGGAATGGTACCTGGAGTGGTGAAGT ACCGCAGTGCTTACCAAAGTTTTGTGGTGACCCTGGTATACCTGCCCAAGGAAAAAGAGAAGGCAAAAGCTTTATATACCAGTCAGAGGTTTCATTCAGC TGCAATTTTCCTTTCATATTAGTGGGATCAAGCACCAGAATATGTCAAGCAGATGGCACTTGGAGTGGTTCATCACCTCACTGCATAGAGCCTACCCAAA CCTCTTGTGAAAACCCAGGTGTGCCTCGGCATGGATCTCAGAACAATACATTCGGATTTCAAGTAGGAAGTGTTGTACAGTTCCATTGCAAAAAAGGACA CCTTCTCCAAGGGTCTACAACACGCACCTGCCTCCCTGATCTTACGTGGAGTGGGATTCAGCCTGAATGCATACCCCACAGCTGTAAACAGCCAGAAACT CCTGCTCATGCAAATGTCGTAGGGATGGACCTTCCATCTCATGGGTATACACTGATTTATACCTGTCAGCCTGGCTTCTTCTTAGCAGGTGGAACAGAAC ATAGAGTGTGTAGATCCGATAACACCTGGACTGGAAAAGTTCCCATTTGTGAAGCTGGTTCTAAAATATTGGTGAAAGATCCTAGACCTGCACTGGGAAC ACCCAGCCCAAAGCTAAGTGTTCCTGATGATGTATTTGCCCAAAATTATATATGGAAAGGCTCTTACAATTTCAAAGGAAGGAAACAACCCATGACCTTA ACAGTTACTAGTTTCAATGCTTCCACTGGGAGAGTTAACGCAACACTGAGCAATAGCAACATGGAGCTGCTACTTTCAGGGGTATATAAAAGCCAGGAAG CTCGCCTAATGTTACGCATATATCTTATTAAAGTACCTGCTCATGCTTCTGTGAAGAAAATGAAGGAAGAAAATTGGGCAATGGATGGCTTTGTTTCTGC TGAGCCTGATGGAGCTACTTATGTATTTCAAGGATTTATTCAAGGCAAAGATTATGGACAATTTGGCCTACAAAGACTGGGACTGAATATGTCAGAAGGT TCAAATTCTTCAAATCAACCTCATGGTACAAATAGTAGTTCTGTAGCCATTGCTATTCTTGTGCCTTTTTTTGCACTTATATTTGCAGGATTTGGATTTT ATCTTTATAAACAAAGGACTGCACCTAAAACACAGTATACAGGATGTTCAGTTCATGAAAATAACAATGGCCAAGCAGCTTTTGAAAATCCCATGTATGA CACCAACGCAAAGTCAGTGGAAGGGAAGGCGGTACGATTTGATCCCAACTTGAACACGGTTTGCACAATGGTATAACGAGGCAACCTTTGCCTTCTTCAG AAGCTTGGAAATCGACACACAAAACAGTGCACATTTAGTTCACTGCTAAACAAATTAAAGCACACTTTTCAGGACTTGCTGGGTCACCTTTTCCTGAGGA ATGATACAGAAGAGTGTTTTTTCATAAACTGGACCATAATTCTTCATGTTTACCATGGAGAGTTTTACAGAAATTTGGCTGCACTCTGAGAGTGCTTACT CACAGTTTATTTGCTTTTTTTAAAAAGGAGATTATTCTAAAATATAAACTTATTTGCATATATTGGAGGAGCATCCACTATCAGTATTTCTGTGCTTTAT AAACTATATTAGAGGGACTGGGTTTAAAAAAAAAGATATAGGGTAGAAATAAGAGCTATACTTACAAGAGTCAATAGATCACTGACTTCTCTTTAACTGT CCTGAGCTACATCACGCCCACAAATCTGTCTTTCATACCACTCTATCTGCCATTCATTCTTGTTAAATGAGGCATTGTTTTCTTTATTTAAGATTGAGTT ATGACTTTAAATGTTTATGAGCTAGTTTATGCCTCGGAAGACATAAGGTTTCCCATTCCAATTTGAATCTTTCTATTTCTTTAGCATCATATTGCTCTTC TTCTTTTAGACTGGTTGTCATAGTTTCTGCAAAGGGCAAGTTCATTGTGCTACCCTCCCAATTCCCCCATTATGGAGTAACCAGTATTATTCAGTGAGCT ATGGGGTAGTGTTTCACTCCTTGCTTCAATATGGTTTTTTCCTATTTATTTTTATTATTTTTTAATCCCAAATGTGATAGTAGCTTCAGTATGTTTCCTC ACCCAAAAACCATTTGGCTGGCAGAAATTATCTAGAAAAATTATTATTTTGCAGTTATCTGAGACACCAAACTTACCATCCTTTATTTTACAATATTTTT GATCGACCAAATAAAATGTCCTAATAATCTACTCTATTTATATCTACATTTCCTTCCAGCTGAGTCTTCAAATTTAGCATTATTTTGACACTTTTAATTT TCATTTAACAATGGATTAGAAAAATATTTTGGTCTAGCCACTAAACATAATGACTGAAAAAAATTATTATTATAAATCACCAATATAAATTTATTGCCTA CAATTGTGGACTTATCATATTTTTATATATTTTTAAATTTCTGTACCTTTATTGTTAAACACCAAGTTTCACATACAAGAGGTTTCTTTCATTGTCAAAT TAAGATATGTATTTGTAAGTTATTGGTGGCTCATTTAAACTGTATCATACAGTAATGCCAGCATTTTTATTTAATAGGTCATCGTCTTCCTTTTATAGCT GTTTTACTTCATTGAATACGATCATGTACCCAGTGTTAACTCTTTGTTGTTGTCCCTTTCAAATATGGATAACTCTGTGAACAGTCTTGACTTTTTGTAT CATGAGACAGAGTGCCTAAGAGAAACCCTTGCACCTGGGAGCGCTGCTTGGCTCTATCTCTACAACATTTAATGAATTTCTTGTAAACCACTTTGAGATA CATTGTTTTGGAAATTCATACAATTTTCTCAACATGGTACTCTACTGGCAGGATGCAGTTTTAAATTTTATGCCATCAGTTATTTATTCTTGTTTATTCA AATGACTGCAATAACAATGATTCATTCATTAATGTTAAGGCTAATACATTTAAGATCTTGTTTAAACAATGTTTCTTCTGCAACTGGCTACTCCTCTTAT ATTAATGCATACACTTTTGTAAAGAAGTATATTTTTATGAAAAGAAACTTTGTAAAAGTATGATGTAAATTTTCAGTGCAATGTAAACAAAATAAAAATG GATAATTGCTTTTGTAAAA

refseq_CSMD3.F2 (forward primer)
refseq_CSMD3.R2 (reverse primer)
Single exon skipping

Frame 0

ETLCPRWRDG*VLVKVAVVSQKHHSLRAVTAHQ QQQQLHCAGLRSRN*ELANNMKGIRKGESRAKES KPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFW NLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPG FPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE EYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTST KSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHP QLTCIANSVNTASWDFPVPICRAEDACGGTMRG SSGIISSPSFPNEYHNNADCTWTIVAEPGDTIS LIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPP PIISNKNWLRLHFVTDSNHRYRGFSAPYQVKKA IDFKSRGFKLFPGKDNSNKFSILNEGGIKTASN LCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVL QGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSN LQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTN KVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVL QVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVG FKVNYKEIEKESCGDPGTPLYGIREGDGFSNRD VLRFECQFGFELIGEKSIVCQENNQWSANIPICI FPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTI ISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPE SPILGTFTGAEVPSHLTSNSHILRLEFQADHSMS GRGFNITYNTFGHNECPDPGIPINARRFGDNFQ LGSSISVICEEGFIKTQGTETITCILMDGKVMW SGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDS LNCEWVIEAEPGHSIKITFERFQTELNYDVLEV HDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLL FTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVH GRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCE KNHWWSHPLPTCDALCGGDVRGPSGTILSPGYP EFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHH DYLLITENGSFTQPLARLTGSDLPPTINAGLYG NFRAQLRFISDFSISYEGFNITFSEYNLEPCED PGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTS EIICLGGGRRVWSAPLPRCVAECGASATNNEGI LLSPNYPLNYENNHECIYSIQVQAGKGINISAR TFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGL TLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFEL SHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPG YTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRF KGESSGRILSPGYPFPYDNNLRCMWMIEVDPGN IVSLQFLAFDTEASHDILRVWDGPPENDMLLKE ISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAI QFSSSVATACRDPGVPMNGTRNGDGREPGDTVV FQCDPGYELQGEERITCIQVENRYFWQPSPPVC IAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTI TVNADYVISLAFISFSIEPNYDFLYIYDGPDSN SPLIGSFQDSKLPERIESSSNTMHLAFRSDGSV SYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYK LGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGW NRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSV GHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVY DGPTQQSSLLSSLSGSHSGESLPLSSGNQITIR FTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEP RFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRC ETVPNSLAQWNDSLPTCIVPCGGILTKRKGTIL SPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSF ATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLL NSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDS CPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSL QGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDF SGVILSPGFPGNYPSSLDCTWTINLPIGFGVHL QFVNFSTETIHDYLEVRSGSSETSTVIGRLSGP QIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQA YQLQSCPDPRPFRNGFVIGNDFTVGQTISFECF PGYTLIGNSALTCLHGVSRNWNHPLPRCEALCG GNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPG NGIYINFTVLQTEPIYDFITVWDGPDQNSPQIG QFSGNTALESVYSTSNQILIKFHSDFTTSGFFV LSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDI IRYQCLPGFTLVGNAILTCRLGERLQMDGAPPV CQVLCPANELRLDSTGVILSPGYPDSYPNLQMC AWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGP NIQSPVLISLSGDYSSAFNITSNGHEVFLQWSA DHGNNKKGFRIRYIAFYCSTPESPPHGYIISQT GGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYH AWDAPVPACQAISCGIPKAPTNGGILTTDYLVG TRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHN KTPRCVVISCGELPTPPNGNKIGTQTSYGSTAIF TCDLGFMLVGSAVRECLSSGLWSESETRCLAGH CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRL IGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY GRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQ ANRQWSHPPPMCKVVNCSDPGIPANSKRESKIE HGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQW DKPLPECIMIDCGHPGVPPNAVLSGEKYTFGST VHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCS GDATGTCGDPGTPGHGSRQESNFRTKSTVRYACD TGYILHGSEERTCLANGSWTGRQPECKAVQCGN PGTTANGKVFRIDGTTFSSSVIYSCMEGYILSG PSVRQCTANGTWSGTLPNCTIISCGDPGIPANGL RYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCT INGTWSGVMPTCRAVTCPTPPQISNGRLEGTNF DWGFSISYICSPGYELSFPAVLTCVGNGTWSGEV PQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFS CNFPFILVGSSTRICQADGTWSGSSPHCIEPTQ TSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGH LLQGSTTRTCLPDLTWSGIQPECIPHSCKQPET PAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTE HRVCRSDNTWTGKVPICEAGSKILVKDPRPALGT PSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTL TVTSFNASTGRVNATLSNSNMELLLSGVYKSQE ARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSA EPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEG SNSSNQPHGTNSSSVAIAILVPFFALIFAGFGF YLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYD TNAKSVEGKAVRFDPNLNTVCTMV*RGNLCLLQ KLGNRHTKQCTFSSLLNKLKHTFQDLLGHLFLR NDTEECFFINWTIILHVYHGEFYRNLAAL*ECLL TVYLLFLKRRLF*NINLFAYIGGASTISISVLY KLY*RDWV*KKRYRVEIRAILTRVNRSLTSL*L S*ATSRPQICLSYHSICHSFLLNEALFSLFKIEL *L*MFMS*FMPRKT*GFPFQFESFYFFSIILLF FF*TGCHSFCKGQVHCATLPIPPLWSNQYYSVS YGVVFHSLLQYGFFLFIFIIF*SQM***LQYVSS PKNHLAGRNYLEKLLFCSYLRHQTYHPLFYNIF DRPNKMS**STLFISTFPSS*VFKFSIILTLLI FI*QWIRKIFWSSH*T**LKKIIIINHQYKFIAY NCGLIIFLYIFKFLYLYC*TPSFTYKRFLSLSN *DMYL*VIGGSFKLYHTVMPAFLFNRSSSSFYS CFTSLNTIMYPVLTLCCCPFQIWITL*TVLTFCI MRQSA*EKPLHLGALLGSISTTFNEFLVNHFEI HCFGNSYNFLNMVLYWQDAVLNFMPSVIYSCLF K*LQ*Q*FIH*C*G*YI*DLV*TMFLLQLATPLI LMHTLL*RSIFL*KETL*KYDVNFQCNVNKIKM DNCFCK

Frame 1

RLCAPVGEMVESSSRLLWYPRNTIHSEL*PRTN NSNNSTAPG*GAGIRSSRII*KGSAKGKAEQRN PNPGSLASEDALNVAA*TSS**RKWGLKVDLRFG TSSFY*RCLV*KDLFIHVVEL*KDLMAL*KALV FHMDIQMVQTAHG***QKNEIEYKLFFSHLL*K KNTTTYHYMMDILILQTLGQG*QDSICHLQ*QVP NLCSHYV*PVILQLVLMDLRYITKNCRVALVEI LVFHPKVYYMAQDSTSGTRSATAV*LDTSLMAT LSSPA*PIQLIQLRGIFLFLSVELKMLVEEQ*ED PVASYPALVFLMSTITMLIALGPL*QSLGTQFH SYLLIFKWKRNMIT*K*KVLSHLPYGYLE*IYH HQLSATKTGSDCILLQTAIIDTVDLVLPIK*KRP *ILNLEDLNCFQGKTTATSFLS*MREVLKQLPI YAQIQENQKMGRESDQILALDQLCSSLVMKIMS YRAQRASPVNG*LKFLLLGVITGLCVK*KRVALI FKDQVVPLHLPTFRSSMTAMHNVSGSSQQ*IQI RLSR*ILKNLIWRLAMIP*QLAMGAKLEILGQC SKC*LEALYQT***A*VAKCGCTFKRTKVLDLLV SRLTTKKLRKKVVVILVHPYMELEKAMDFLIVM F*GLNASLGLN*LERNPLFVKRITNGLQTYPSV SFPACLTLLHQWEQFFLLITQKGMEII*IASGR* SLIQGAGYIFLSMTLTWNPSLISLLLKMVTLQN PQFLEPLLGLRCLPILLVIVTYCDWNFRLTTQC QDVALTSLTTHLDIMNALILEYQSMHGGLGTTFN *EVQFQLFVKKDLLKPREQKQLHVFLWMEK*CG VD*FQNVEPHVVAIFQLPVE*FSHQDGQDTTKT L*IVSG*LKLNLDTLSKLHLKDFRLN*IMMFWKF MMGQIFCHPCLDLTMAPKCPSFYLVAVILYTFY LQQTTVVPIMVSRFIMKVLQ*TRILVWTLAYLY MAVAMVMISPLALLFHLVVIQDTG*VMKSPFYAK KTTGGVIHFQPVMHYVEEMLEGLVEQSYHLVTR NFIQIL*IVHGLLM*PMEKVCSSTSTLFIWKTI MTTY*SQRMAVLPNHWHA*LVQIFLQQSMLVSME ISGLNCVSFQIFQYHMKDLT*HSLNITLNLVKI LAFLNMVVESGSTLGLVTL*PSHALRVIDWKEH QRSSVLVVADECGVHLCQGVWLNVVHLQRIMKEF CCLQIIHSTMKTTMNAFIVFRFKQERESIFQPE HFI*HKEMFLRFMMEKIKRLIY*VLLLVHLCAD *HLVVLQINSG*NLIPILKGQMKAFNLCIPVLNS HTVKILAFHNLDTRSVTKATLLVAPSFMDAIQA TLSTEVAFSSA*QGREGHGTILCLPVLLNVEVV LKENHQEESYLLAILFHMTITCVACG*LR*ILEI LSACSFLLLIRKHHMIYSESGTVHQKMICF*RK LVDLLFLKEFIAPSI**PSSLTRIFILANLDLQ FSFQVLLPLRVVTQGSP*MGLEMGMEENLGTLLF FNVTQDMNFKERKE*PAFR*KIGTSGSPAHQSV *HPVEAI*QDLQALFFHQTSLIHIRIAETVTGL SPSMQTMLSPWRSSVLA*NQTMTSSISMMDQTVI AH*LEVFKTASYQRE*KAAQIQCIWLFGVMDLL VTLDFI*NTKQNCESPALIQAI**MAPDLEWII N*GQQSPITVMLVMFFKVIQHSPVSWEMMEDLDG IEPCQVVMRPVEVVQQVQKALFYHQTIQKITVW DIIVFIL*QFQRSLWCLASLYFSRHHSTMLLRC MMGQLSNLLCYLPSQDPIQENHFH*VQVIRSQFD LLQLDQ*QLRDFTLFTKLFLEQVLHNAVLCLNQ DSEEELAMNLQSVHRFFLIVIQDIFSMDP*QLG VKQCPILWPSGMIPYLLVLCPVVEF*LSAKGLFC HLDTLSLMTTI*IVCGRSQCQRELAFKCKLLAL LQNIIGILWTFMMGETTMLQDLEAIQEQQYPIF *IVRLIICI*IFNQTSVFLLQDFILNTQQLVWIP VLNHKLLAVELKLETDIWLEM*YPFSVIKDILF RVTLTLHVCQDL*EDGIIQSQFV*LSVVVLCQT SVV*SSVLGFLETIPAV*IAHGQ*IYP*VLVYIS SL*IFLQKPYMIIWKYEVDPQKLVLLLAGLVVL KYHLPYSAPPMKPAYIFTVTIHKTNKGFILYTK PISCKAVLIHARFEMVL*LVMILLWVKPFHLNVS QDTH*LEIQLSHAFTESVVIGIIHFQGVKLFVV GI*LQ*MAPFILLGILMNIQTFKIVFGL*EYPL GMASTSILLSFKQNQYMISLLYGMDQTKIHLRSV SSVAIPLWNQSTVLQIRF*SNSTVISQQVAFLC SVITPIN*GCANLHHLCPMLKF*RKMMNLK*VI LLGISVFQDLL*LVMQF*RAD*ENDCRWMEHLQF VKCSVLPMNYG*ILLESY*ALDILTVTQIFKCV HGAFQWKRVIISPCL*NSSRQKRNLMFFRCMMD QIFKVQCLFPSVGIIHLLLI*QAMVMKYFFSGQQ IMAITKKASG*DI*LSTVVHQNPHLMDILSVRQ VGSLTVWSVGPVIEDSDLLEKAVLCAESLPMGI MHGMRQSLPVKQFPVGFLKLQQMEEY*QQTIW*E RELPIFVMMDIDCHPKNSLQLYANQMEHGAIIT RPLAVLLFPVENYLHLQMEIRLELKLHMAQQLS LPATWDSCLWALL*GNAFPQVFGVNLKPDA*RVI VEFQN*L*MVKSLEKIMDIETQLYINVILVFD* LVLQ*GYVNRITIGLVSSHPVCLLAVVTLVVQF MEEQVEMGSTLMMW*HSHAILGILCKGQQRHSAR PTDSGAILHLCAKWSTVLILEFQPILKEKVK*N MEILLTALWYSMTAILDIFYLDLQF*YVNQMDN GTNLYQNVS*LTVDTLAFLLMQSCLARSILLGLL FTIPAQESVPF*ASHQEPAN*MAIGVDHNLIVQ VMLLGHVAIQVLPAMALDRKAISELKVLYVMLV ILVTSFMAQKKEHV*LMAVGPEGSQSAKLCSVVT QEPQPMGKSSELMAQHFLVQSFIPAWRDTSFLD LQLDSAQPMEHGLELYLTVQ*SVVETQVYQPMD *DMEMIMWLDKMFLTCASQATRWN*MAPESGLVQ LMAHGVE*CQLVELLPAQLLPRSLMEGWKEQIS TGALVLATSVLQAMSYPSLLF*PV*GMVPGVVK YRSAYQSFVVTLVYLPKEKEKAKALYTSQRFHSA AIFLSY*WDQAPEYVKQMALGVVHHLTA*SLPK PLVKTQVCLGMDLRTIHSDFK*EVLYSSIAKKD TFSKGLQHAPASLILRGVGFSLNAYPTAVNSQKL LLMQMS*GWTFHLMGIH*FIPVSLASS*QVEQN IECVDPITPGLEKFPFVKLVLKYW*KILDLHWE HPAQS*VFLMMYLPKIIYGKALTISKEGNNP*P* QLLVSMLPLGELTQH*AIATWSCYFQGYIKARK LA*CYAYILLKYLLMLL*RK*RKKIGQWMALFL LSLMELLMYFKDLFKAKIMDNLAYKDWD*ICQKV QILQINLMVQIVVL*PLLFLCLFLHLYLQDLDF IFINKGLHLKHSIQDVQFMKITMAKQLLKIPCM TPTQSQWKGRRYDLIPT*TRFAQWYNEATFAFFR SLEIDTQNSAHLVHC*TN*STLFRTCWVTFS*G MIQKSVFS*TGP*FFMFTMESFTEIWLHSESAY SQFICFF*KGDYSKI*TYLHILEEHPLSVFLCFI NYIRGTGFKKKDIG*K*ELYLQESIDH*LLFNC PELHHAHKSVFHTTLSAIHSC*MRHCFLYLRLS YDFKCL*ASLCLGRHKVSHSNLNLSISLASYCSS SFRLVVIVSAKGKFIVLPSQFPHYGVTSIIQ*A MG*CFTPCFNMVFSYLFLLFFNPKCDSSFSMFP HPKTIWLAEII*KNYYFAVI*DTKLTILYFTIFL IDQIKCPNNLLYLYLHFLPAESSNLALF*HF*F SFNNGLEKYFGLATKHND*KKLLL*ITNINLLP TIVDLSYFYIFLNFCTFIVKHQVSHTRGFFHCQI KICICKLLVAHLNCIIQ*CQHFYLIGHRLPFIA VLLH*IRSCTQC*LFVVVPFKYG*LCEQS*LFV S*DRVPKRNPCTWERCLALSLQHLMNFL*TTLRY IVLEIHTIFSTWYSTGRMQF*ILCHQLFILVYS NDCNNNDSFINVKANTFKILFKQCFFCNWLLLL Y*CIHFCKEVYFYEKKLCKSMM*IFSAM*TK*KW IIAFVK

Frame 2

DFVPPLERWLSPRQGCCGIPETPFTPSCDRAPT TATTPLRRAEEQELGARE*YERDPQRGKPSKGI QTLGAWQAKMR*MWPPRLHPDEENGD*KWIYVL EPRLFIDGVLCERIYLYMWWNFKRT*WHYRKPWF SIWISKWCKLHMGNNSRRTK*NTNCFSVICSRR RIRLLIII*WTSSSYKL*DKVNRIPSATSSDKY QICVLTTFDQ*FCS*CSWI*GILRRIAE*LLWKS WCSTQRCIIWHKIRRRGQDPLQLCNWIHP*WPP SAHLHSQFS*YSFVGFSCSYL*S*RCLWRNNER IQWHHIQP*FS**VP*QC*LHLDHCSRAWGHNFT HIY*FSNGREI*LLRNRRF*ATYHMVIWNEYTT TNYQQQKLAQTAFCYRQQSSIPWI*CSLSSEKG HRF*I*RI*IVSRERQQQQVFYLK*GRY*NSFQF MPRSRRTRKWEENRIRF*PWINCAVLL**RLCP TGRKEHHLSTDS*SFCCLE*SQACV*SENVWL* SSRTKWYLYISQLSVPV*QQCTMCLGHHSSEYK* GYPDKF*RI*SGDWL*YLDNWRWGRSWRS*DSA PSADWKLCTRLDSEHE*PNVAAPSNGRKCWICW FQG*LQRN*ERKLW*SWYTLIWN*RRRWIF*S*C FKV*MPVWV*INWREIHCLSRE*PMVCKHTHLY LSLPV*LYCTNGNSSFS*LPRRVWK*FKLHLDD NL*SREPDTSFFQ*L*PGIPV*FPCC*RW*LSRI PNSWNLYWG*GAFPSY***SHTAIGISG*PLNV RTWL*HHLQHIWT**MP*SWNTNQCTAVWGQLS IRKFNFSYL*RRIY*NPGNRNNYMYSYGWKSNVE WTDSKMWSPMWWPFFSSQWSDSLTRMARILQRL FEL*VGD*S*TWTLYQNYI*KISD*TEL*CSGS S*WAKSSVTLAWILQWHPSAPVSI**Q*FYIPSI YNRQQSFQ*WFQDSL*KCYSEHVFLFGPWHTCT WPSLWS*FLHWLYCFI*L*FRIQVES*RAPSMR KKPLVESSTSNL*CIMWRRC*RA*WNNLITWLPG ILSKFSELYMDC*CNPWKRCAVQLPHFSFGRPS *LLTDHREWQFYPTTGTPDWFRSSSNNQCWSLW KFQGSIAFHFRFFNII*RI*HNIL*I*P*TL*RS WHSSIW*SNRVQLWDW*HSDLLMLFGLSTGRNI RDHLSWWWPTSVECTSAKVCG*MWCICNE**RN FAVSKLSTQL*KQP*MHL*YSGSSRKGNQYFSQN ISFSTRRCS*DL*WKR*NDSSTRCFYWCIYART DT**YFKSTLARI*FRY*RDR*RLSTCVYQF*T LTL*RSWHSTIWIQDQ*PRPLCW*HHHLWMQSRL HSPRK*PSQVHDRGEKGMGLSSAFLYC*MWRSF *RRIIRKNLISWLSFSI*Q*PALHVDD*GRSWK YCQLAVSCF*YGSIT*YTPSLGRSTRK*YAFKGN *WISYS*RNS*HPQYSNHPV*HGFLY*QIWICN SVFKFCCHCVS*PRGPHEWDSKWGWKRTWGHCC FSM*PRI*TSRRGKNNLHSGRKSVLLAAQPTSLY STLWRQFNRIFRLYSFTKLPSSISA*QRL*LDY HRQCRLCYLLGVHQF*HRTKL*LPLYL*WTRQ* *PTDWKFSRQQVTRENRKQLKYNAFGFSE*WIC* LHWISSRIQSKTARVLL*SRQYNEWHQTWNGL* IRVNSHLLL*CWLCSSRLFNTHLYHGR*WKTWM E*SLAKLSCALWKSFNRFRRHCSITKLSKKLQCG T*LCLFYSSSKGVCGVWPVCIFPDITPRCC*GV *WANSAIFSVIFPLRIPFRRITSTEFR*SDHNS IYFSWTNNS*GISLCLPSCS*NKFYTMQFCA*TK IRKKNWQ*ICSRFIGSF*L*SRIYSPWIHSN*V *NSAQFFGPVE*FLTYLYCALWWNFN*AQRDYF VTWIP*AL*QQSELCVEDHSARGSWHSSASC*LC YRT*LGFSGLL*WGRQQCSKTWKLFRNNNTPSF E*YV**SVSKFSIRHQCFCCRISS*IHSNWFGF LS*TTNS*QWN*NWRQIYGWRCSILSV*SRIFSS GSLSHYMYARTCKKMELSNPNLFSSVWWCYVRL QWCDPQSWVSWKLSQQFRLHMDNKSTHRFWCTS PVCKFFYRNHT*LFGSTKWILRN*YCYWPA*WSS NTIFLIQHHP*NQLIFSQ*LFTKQTRVSYCIPS LSVAKLS*STPVSKWFCNW**FYCGSNHFI*MF PRIHINWKFSSHMPSRSQS*LESSTSKV*SSLWW EYNCNEWHHLFSWVS**ISKLSRLFLACKSTPW EWHLHQFYCPSNRTNI*FHYCMGWTRPKFTSDR SVQWQYRFGISLQYFKSDSNQIPQ*FHNKWLFCA QLSRLSTKGVPTSTTCAQC*NFDGR**I*NR*Y Y*VSVSSRIYFSW*CNSDVQIRRTTADGWSTSS LSSALSCQ*ITARFYWSHIEPWIS*QLPKSSNVC MEHFSGKGL*YHHVCRILPDRKGI*CSSGV*WT KYSKSSAYFPQWGLFICF*YNKQWS*SISSVVS RSWQ*QKRLPDKIYSFLL*YTRIPTSWIYYQSDR WAA*QCGPLGL*SRIPTCWKKQCCVQKVFLWVS CMGCASPCLSSNFLWDS*SSNKWRNTNNRLFGR NASYLFL**WISIVIQRTHYSCMPIRWNMEQS*Q DPSLCCYFLWRTTYTSKWK*DWNSNFIWLNSYL YLRLGIHACGLCCKGMPFLRSLE*I*NQMPSGS LWNSRTDCEWSSHWRKLWI*RHSCISM*SWFSID WFFSEDMSTGSQLVWSAPILCAC*LWSPW*SNL WKNKWKWVQL**CGNILMQYWVSYARANKGTVP GQQTVEPSSTYVQSGQLF*SWNSSQF*KRK*NRT WKFYLRHCGIL*LQSWIFFIWIFSFDMSTKWTM GQTFTRMYHD*LWTPWRSS*CSPVWREVYFWVY CSLFLHRKAFPFRPVIKNLPIEWPLEWITTSLFR *CYWDMWRSRYSRPWL*TGKQFQN*KYCTLCL* YWLHPSWLRRKNMFS*WQLDRKAARVQSCAVW* PRNHSQWESLPN*WHNIF*FSHLFLHGGIHPFWT FS*TVHSQWNMVWNFT*LYNNQLWRPRYTSQWT EIWR*LCGWTKCFLHVPARLHDGIEWLQNQDLY N*WHMEWSNANL*SCYLPNSSPDL*WKAGRNKFR LGL*Y*LHLFSRL*AILPCCFDLCREWYLEW*S TAVLTKVLW*PWYTCPRKKRRQKLYIPVRGFIQ LQFSFHISGIKHQNMSSRWHLEWFITSLHRAYPN LL*KPRCASAWISEQYIRISSRKCCTVPLQKRT PSPRVYNTHLPP*SYVEWDSA*MHTPQL*TARN SCSCKCRRDGPSISWVYTDLYLSAWLLLSRWNRT *SV*IR*HLDWKSSHL*SWF*NIGERS*TCTGN TQPKAKCS**CICPKLYMERLLQFQRKETTHDL NSY*FQCFHWES*RNTEQ*QHGAATFRGI*KPGS SPNVTHISY*STCSCFCEENEGRKLGNGWLCFC *A*WSYLCISRIYSRQRLWTIWPTKTGTEYVRR FKFFKSTSWYK**FCSHCYSCAFFCTYICRIWIL SL*TKDCT*NTVYRMFSS*K*QWPSSF*KSHV* HQRKVSGREGGTI*SQLEHGLHNGITRQPLPSS EAWKSTHKTVHI*FTAKQIKAHFSGLAGSPFPEE *YRRVFFHKLDHNSSCLPWRVLQKFGCTLRVLT HSLFAFFKKEIILKYKLICIYWRSIHYQYFCAL *TILEGLGLKKKI*GRNKSYTYKSQ*ITDFSLTV LSYITPTNLSFIPLYLPFILVK*GIVFFI*D*V MTLNVYELVYASEDIRFPIPI*IFLFL*HHIAL LLLDWLS*FLQRASSLCYPPNSPIME*PVLFSEL WGSVSLLASIWFFPIYFYYFLIPNVIVASVCFL TQKPFGWQKLSRKIIILQLSETPNLPSFILQYF *STK*NVLIIYSIYIYISFQLSLQI*HYFDTFNF HLTMD*KNILV*PLNIMTEKNYYYKSPI*IYCL QLWTYHIFIYF*ISVPLLLNTKFHIQEVSFIVK LRYVFVSYWWLI*TVSYSNASIFI**VIVFLL*L FYFIEYDHVPSVNSLLLSLSNMDNSVNSLDFLY HETECLRETLAPGSAAWLYLYNI**ISCKPL*D TLFWKFIQFSQHGTLLAGCSFKFYAISYLFLFIQ MTAITMIHSLMLRLIHLRSCLNNVSSATGYSSY INAYTFVKKYIFMKRNFVKV*CKFSVQCKQNKN G*LLL*

Sequence NM_198123

GAGACTTTGTGCCCCCGTTGGAGAGATGGTTGAGTCCTCGTCAAGGTTGCTGTGGTATCCCAGAAACACCATTCACTCCGAGCTGTGACCGCGCACCAAC AACAGCAACAACTCCACTGCGCCGGGCTGAGGAGCAGGAATTAGGAGCTCGCGAATAATATGAAAGGGATCCGCAAAGGGGAAAGCCGAGCAAAGGAATC CAAACCCTGGGAGCCTGGCAAGCGAAGATGCGCTAAATGTGGCCGCCTAGACTTCATCCTGATGAAGAAAATGGGGATTAAAAGTGGATTTACGTTTTGG AACCTCGTCTTTTTATTGACGGTGTCTTGTGTGAAAGGATTTATTTATACATGTGGTGGAACTTTAAAAGGACTTAATGGCACTATAGAAAGCCCTGGTT TTCCATATGGATATCCAAATGGTGCAAACTGCACATGGGTAATAATAGCAGAAGAACGAAATAGAATACAAATTGTTTTTCAGTCATTTGCTCTAGAAGA AGAATACGACTACTTATCATTATATGATGGACATCCTCATCCTACAAACTTTAGGACAAGGTTAACAGGATTCCATCTGCCACCTCCAGTGACAAGTACC AAATCTGTGTTCTCACTACGTTTGACCAGTGATTTTGCAGTTAGTGCTCATGGATTTAAGGTATATTACGAAGAATTGCAGAGTAGCTCTTGTGGAAATC CTGGTGTTCCACCCAAAGGTGTATTATATGGCACAAGATTCGACGTCGGGGACAAGATCCGCTACAGCTGTGTAACTGGATACATCCTTGATGGCCACCC TCAGCTCACCTGCATAGCCAATTCAGTTAATACAGCTTCGTGGGATTTTCCTGTTCCTATCTGTAGAGCTGAAGATGCTTGTGGAGGAACAATGAGAGGA TCCAGTGGCATCATATCCAGCCCTAGTTTTCCTAATGAGTACCATAACAATGCTGATTGCACTTGGACCATTGTAGCAGAGCCTGGGGACACAATTTCAC TCATATTTACTGATTTTCAAATGGAAGAGAAATATGATTACTTAGAAATAGAAGGTTCTGAGCCACCTACCATATGGTTATCTGGAATGAATATACCACC ACCAATTATCAGCAACAAAAACTGGCTCAGACTGCATTTTGTTACAGACAGCAATCATCGATACCGTGGATTTAGTGCTCCCTATCAAGGTTCTTCTACA TTGACCCACACTACCTCCACTGGTGAGTTAGAGGAGCATAACAGGACTACCACTGGTGCTATTGCTGTTGCTAGCACACCTGCAGATGTTACTGTATCCA GTGTTACAGCTGTCACCATCCATAGACTTTCCGAGGAACAGCGAGTGCAAGTTACGAGTCTCAGAAATTCAGGTCTGGACCCCAACACGTCCAAGGACGG GCTCTCTCCTCATCCAGCAGATACACAAAGTACCAGGAGAAGACCAAGACATGCTGAACAGATAGAAAGAACTAAAGAGCTTGCAGTTGTTACTCATAGA GTGAAAAAGGCCATAGATTTTAAATCTAGAGGATTTAAATTGTTTCCAGGGAAAGACAACAGCAACAAGTTTTCTATCTTAAATGAGGGAGGTATTAAAA CAGCTTCCAATTTATGCCCAGATCCAGGAGAACCAGAAAATGGGAAGAGAATCGGATCAGATTTTAGCCTTGGATCAACTGTGCAGTTCTCTTGTGATGA AGATTATGTCCTACAGGGCGCAAAGAGCATCACCTGTCAACGGATAGCTGAAGTTTTTGCTGCTTGGAGTGATCACAGGCCTGTGTGTAAAGTGAAAACG TGTGGCTCTAATCTTCAAGGACCAAGTGGTACCTTTACATCTCCCAACTTTCCGTTCCAGTATGACAGCAATGCACAATGTGTCTGGGTCATCACAGCAG TGAATACAAATAAGGTTATCCAGATAAATTTTGAAGAATTTGATCTGGAGATTGGCTATGATACCTTGACAATTGGCGATGGGGGCGAAGTTGGAGATCC TAGGACAGTGCTCCAAGTGCTGACTGGAAGCTTTGTACCAGACTTGATAGTGAGCATGAGTAGCCAAATGTGGCTGCACCTTCAAACGGACGAAAGTGTT GGATCTGTTGGTTTCAAGGTTAACTACAAAGAAATTGAGAAAGAAAGTTGTGGTGATCCTGGTACACCCTTATATGGAATTAGAGAAGGCGATGGATTTT CTAATCGTGATGTTTTAAGGTTTGAATGCCAGTTTGGGTTTGAATTAATTGGAGAGAAATCCATTGTTTGTCAAGAGAATAACCAATGGTCTGCAAACAT ACCCATCTGTATCTTTCCCTGCCTGTCTAACTTTACTGCACCAATGGGAACAGTTCTTTCTCCTGATTACCCAGAAGGGTATGGAAATAATTTAAATTGC ATCTGGACGATAATCTCTGATCCAGGGAGCCGGATACATCTTTCTTTCAATGACTTTGACCTGGAATCCCAGTTTGATTTCCTTGCTGTTAAAGATGGTG ACTCTCCAGAATCCCCAATTCTTGGAACCTTTACTGGGGCTGAGGTGCCTTCCCATCTTACTAGTAATAGTCACATACTGCGATTGGAATTTCAGGCTGA CCACTCAATGTCAGGACGTGGCTTTAACATCACTTACAACACATTTGGACATAATGAATGCCCTGATCCTGGAATACCAATCAATGCACGGCGGTTTGGG GACAACTTTCAATTAGGAAGTTCAATTTCAGTTATTTGTGAAGAAGGATTTATTAAAACCCAGGGAACAGAAACAATTACATGTATTCTTATGGATGGAA AAGTAATGTGGAGTGGACTGATTCCAAAATGTGGAGCCCCATGTGGTGGCCATTTTTCAGCTCCCAGTGGAGTGATTCTCTCACCAGGATGGCCAGGATA CTACAAAGACTCTTTGAATTGTGAGTGGGTGATTGAAGCTGAACCTGGACACTCTATCAAAATTACATTTGAAAGATTTCAGACTGAACTGAATTATGAT GTTCTGGAAGTTCATGATGGGCCAAATCTTCTGTCACCCTTGCTTGGATCTTACAATGGCACCCAAGTGCCCCAGTTTCTATTTAGTAGCAGTAATTTTA TATACCTTCTATTTACAACAGACAACAGTCGTTCCAATAATGGTTTCAAGATTCATTATGAAAGTGTTACAGTGAACACGTATTCTTGTTTGGACCCTGG CATACCTGTACATGGCCGTCGCTATGGTCATGATTTCTCCATTGGCTCTACTGTTTCATTTAGTTGTGATTCAGGATACAGGTTGAGTCATGAAGAGCCC CTTCTATGCGAAAAAAACCACTGGTGGAGTCATCCACTTCCAACCTGTGATGCATTATGTGGAGGAGATGTTAGAGGGCCTAGTGGAACAATCTTATCAC CTGGTTACCCGGAATTTTATCCAAATTCTCTGAATTGTACATGGACTGTTGATGTAACCCATGGAAAAGGTGTGCAGTTCAACTTCCACACTTTTCATTT GGAAGACCATCATGACTACTTACTGATCACAGAGAATGGCAGTTTTACCCAACCACTGGCACGCCTGACTGGTTCAGATCTTCCTCCAACAATCAATGCT GGTCTCTATGGAAATTTCAGGGCTCAATTGCGTTTCATTTCAGATTTTTCAATATCATATGAAGGATTTAACATAACATTCTCTGAATATAACCTTGAAC CTTGTGAAGATCCTGGCATTCCTCAATATGGTAGTCGAATCGGGTTCAACTTTGGGATTGGTGACACTCTGACCTTCTCATGCTCTTCGGGTTATCGACT GGAAGGAACATCAGAGATCATCTGTCTTGGTGGTGGCCGACGAGTGTGGAGTGCACCTCTGCCAAGGTGTGTGGCTGAATGTGGTGCATCTGCAACGAAT AATGAAGGAATTTTGCTGTCTCCAAATTATCCACTCAACTATGAAAACAACCATGAATGCATTTATAGTATTCAGGTTCAAGCAGGAAAGGGAATCAATA TTTCAGCCAGAACATTTCATTTAGCACAAGGAGATGTTCTTAAGATTTATGATGGAAAAGATAAAACGACTCATCTACTAGGTGCTTTTACTGGTGCATC TATGCGCGGACTGACACTTAGTAGTACTTCAAATCAACTCTGGCTAGAATTTAATTCCGATACTGAAGGGACAGATGAAGGCTTTCAACTTGTGTATACC AGTTTTGAACTCTCACACTGTGAAGATCCTGGCATTCCACAATTTGGATACAAGATCAGTGACCAAGGCCACTTTGCTGGTAGCACCATCATTTATGGAT GCAATCCAGGCTACACTCTCCACGGAAGTAGCCTTCTCAAGTGCATGACAGGGGAGAGAAGGGCATGGGACTATCCTCTGCCTTCCTGTATTGCTGAATG TGGAGGTCGTTTTAAAGGAGAATCATCAGGAAGAATCTTATCTCCTGGCTATCCTTTTCCATATGACAATAACCTGCGTTGCATGTGGATGATTGAGGTA GATCCTGGAAATATTGTCAGCTTGCAGTTTCTTGCTTTTGATACGGAAGCATCACATGATATACTCCGAGTCTGGGACGGTCCACCAGAAAATGATATGC TTTTAAAGGAAATTAGTGGATCTCTTATTCCTGAAGGAATTCATAGCACCCTCAATATAGTAACCATCCAGTTTGACACGGATTTTTATATTAGCAAATC TGGATTTGCAATTCAGTTTTCAAGTTCTGTTGCCACTGCGTGTCGTGACCCAGGGGTCCCCATGAATGGGACTCGAAATGGGGATGGAAGAGAACCTGGG GACACTGTTGTTTTTCAATGTGACCCAGGATATGAACTTCAAGGAGAGGAAAGAATAACCTGCATTCAGGTAGAAAATCGGTACTTCTGGCAGCCCAGCC CACCAGTCTGTATAGCACCCTGTGGAGGCAATTTAACAGGATCTTCAGGCTTTATTCTTTCACCAAACTTCCCTCATCCATATCCGCATAGCAGAGACTG TGACTGGACTATCACCGTCAATGCAGACTATGTTATCTCCTTGGCGTTCATCAGTTTTAGCATAGAACCAAACTATGACTTCCTCTATATCTATGATGGA CCAGACAGTAATAGCCCACTGATTGGAAGTTTTCAAGACAGCAAGTTACCAGAGAGAATAGAAAGCAGCTCAAATACAATGCATTTGGCTTTTCGGAGTG ATGGATCTGTTAGTTACACTGGATTTCATCTAGAATACAAAGCAAAACTGCGAGAGTCCTGCTTTGATCCAGGCAATATAATGAATGGCACCAGACTTGG AATGGATTATAAATTAGGGTCAACAGTCACCTATTACTGTGATGCTGGTTATGTTCTTCAAGGTTATTCAACACTCACCTGTATCATGGGAGATGATGGA AGACCTGGATGGAATAGAGCCTTGCCAAGTTGTCATGCGCCCTGTGGAAGTCGTTCAACAGGTTCAGAAGGCACTGTTCTATCACCAAACTATCCAAAAA ATTACAGTGTGGGACATAATTGTGTTTATTCTATAGCAGTTCCAAAGGAGTTTGTGGTGTTTGGCCAGTTTGTATTTTTCCAGACATCACTCCACGATGT TGTTGAGGTGTATGATGGGCCAACTCAGCAATCTTCTCTGTTATCTTCCCTCTCAGGATCCCATTCAGGAGAATCACTTCCACTGAGTTCAGGTAATCAG ATCACAATTCGATTTACTTCAGTTGGACCAATAACAGCTAAGGGATTTCACTTTGTTTACCAAGCTGTTCCTAGAACAAGTTCTACACAATGCAGTTCTG TGCCTGAACCAAGATTCGGAAGAAGAATTGGCAATGAATTTGCAGTCGGTTCATCGGTTCTTTTTGATTGTAATCCAGGATATATTCTCCATGGATCCAT AGCAATTAGGTGTGAAACAGTGCCCAATTCTTTGGCCCAGTGGAATGATTCCTTACCTACTTGTATTGTGCCCTGTGGTGGAATTTTAACTAAGCGCAAA GGGACTATTTTGTCACCTGGATACCCTGAGCCTTATGACAACAATCTGAATTGTGTGTGGAAGATCACAGTGCCAGAGGGAGCTGGCATTCAAGTGCAAG TTGTTAGCTTTGCTACAGAACATAATTGGGATTCTCTGGACTTTTATGATGGGGGAGACAACAATGCTCCAAGACTTGGAAGCTATTCAGGAACAACAAT ACCCCATCTTTTGAATAGTACGTCTAATAATCTGTATCTAAATTTTCAATCAGACATCAGTGTTTCTGCTGCAGGATTTCATCTTGAATACACAGCAATT GGTTTGGATTCCTGTCCTGAACCACAAACTCCTAGCAGTGGAATTAAAATTGGAGACAGATATATGGTTGGAGATGTAGTATCCTTTCAGTGTGATCAAG GATATTCTCTTCAGGGTCACTCTCACATTACATGTATGCCAGGACCTGTAAGAAGATGGAATTATCCAATCCCAATTTGTTTAGCTCAGTGTGGTGGTGC TATGTCAGACTTCAGTGGTGTGATCCTCAGTCCTGGGTTTCCTGGAAACTATCCCAGCAGTTTAGATTGCACATGGACAATAAATCTACCCATAGGTTTT GGTGTACATCTCCAGTTTGTAAATTTTTCTACAGAAACCATACATGATTATTTGGAAGTACGAAGTGGATCCTCAGAAACTAGTACTGTTATTGGCCGGC TTAGTGGTCCTCAAATACCATCTTCCTTATTCAGCACCACCCATGAAACCAGCTTATATTTTCACAGTGACTATTCACAAAACAAACAAGGGTTTCATAT TGTATACCAAGCCTATCAGTTGCAAAGCTGTCCTGATCCACGCCCGTTTCGAAATGGTTTTGTAATTGGTAATGATTTTACTGTGGGTCAAACCATTTCA TTTGAATGTTTCCCAGGATACACATTAATTGGAAATTCAGCTCTCACATGCCTTCACGGAGTCAGTCGTAATTGGAATCATCCACTTCCAAGGTGTGAAG CTCTTTGTGGTGGGAATATAACTGCAATGAATGGCACCATTTATTCTCCTGGGTATCCTGATGAATATCCAAACTTTCAAGATTGTTTTTGGCTTGTAAG AGTACCCCCTGGGAATGGCATCTACATCAATTTTACTGTCCTTCAAACAGAACCAATATATGATTTCATTACTGTATGGGATGGACCAGACCAAAATTCA CCTCAGATCGGTCAGTTCAGTGGCAATACCGCTTTGGAATCAGTCTACAGTACTTCAAATCAGATTCTAATCAAATTCCACAGTGATTTCACAACAAGTG GCTTTTTTGTGCTCAGTTATCACGCCTATCAACTAAGGGTGTGCCAACCTCCACCACCTGTGCCCAATGCTGAAATTTTGACGGAAGATGATGAATTTGA AATAGGTGATATTATTAGGTATCAGTGTCTTCCAGGATTTACTTTAGTTGGTAATGCAATTCTGACGTGCAGATTAGGAGAACGACTGCAGATGGATGGA GCACCTCCAGTTTGTCAAGTGCTCTGTCCTGCCAATGAATTACGGCTAGATTCTACTGGAGTCATATTGAGCCCTGGATATCCTGACAGTTACCCAAATC TTCAAATGTGTGCATGGAGCATTTCAGTGGAAAAGGGTTATAATATCACCATGTTTGTAGAATTCTTCCAGACAGAAAAGGAATTTGATGTTCTTCAGGT GTATGATGGACCAAATATTCAAAGTCCAGTGCTTATTTCCCTCAGTGGGGATTATTCATCTGCTTTTAATATAACAAGCAATGGTCATGAAGTATTTCTT CAGTGGTCAGCAGATCATGGCAATAACAAAAAAGGCTTCCGGATAAGATATATAGCTTTCTACTGTAGTACACCAGAATCCCCACCTCATGGATATATTA TCAGTCAGACAGGTGGGCAGCTTAACAGTGTGGTCCGTTGGGCCTGTGATCGAGGATTCCGACTTGTTGGAAAAAGCAGTGCTGTGTGCAGAAAGTCTTC CTATGGGTATCATGCATGGGATGCGCCAGTCCCTGCCTGTCAAGCAATTTCCTGTGGGATTCCTAAAGCTCCAACAAATGGAGGAATACTAACAACAGAC TATTTGGTAGGAACGCGAGTTACCTATTTTTGTAATGATGGATATCGATTGTCATCCAAAGAACTCACTACAGCTGTATGCCAATCAGATGGAACATGGA GCAATCATAACAAGACCCCTCGCTGTGTTGTTGTTACATGTCCAAGCATCAATTCCTTTATCTTGGAACATGGAAGATGGCGAATTGTGAATGGCTCCCA TTATGAATACAAAACCAAAGTAGTTTTCAGCTGTGACCCTGGTTATCATGGACTAGGTCCTGCCTCCATCGAATGTCTTCCTAATGGTACTTGGAGTTGG AGAAATGAAAGACCATATTGCCAAATTATTTCCTGTGGAGAACTACCTACACCTCCAAATGGAAATAAGATTGGAACTCAAACTTCATATGGCTCAACAG CTATCTTTACCTGCGACTTGGGATTCATGCTTGTGGGCTCTGCTGTAAGGGAATGCCTTTCCTCAGGTCTTTGGAGTGAATCTGAAACCAGATGCCTAGC GGGTCATTGTGGAATTCCAGAACTGATTGTGAATGGTCAAGTCATTGGAGAAAATTATGGATATAGAGACACAGTTGTATATCAATGTAATCCTGGTTTT CGATTGATTGGTTCTTCAGTGAGGATATGTCAACAGGATCACAATTGGTCTGGTCAGCTCCCATCCTGTGTGCCTGTTAGCTGTGGTCACCCTGGTAGTC CAATTTATGGAAGAACAAGTGGAAATGGGTTCAACTTTAATGATGTGGTAACATTCTCATGCAATATTGGGTATCTTATGCAAGGGCCAACAAAGGCACA GTGCCAGGCCAACAGACAGTGGAGCCATCCTCCACCTATGTGCAAAGTGGTCAACTGTTCTGATCCTGGAATTCCAGCCAATTCTAAAAGAGAAAGTAAA ATAGAACATGGAAATTTTACTTACGGCACTGTGGTATTCTATGACTGCAATCCTGGATATTTTTTATTTGGATCTTCAGTTTTGATATGTCAACCAAATG GACAATGGGACAAACCTTTACCAGAATGTATCATGATTGACTGTGGACACCCTGGCGTTCCTCCTAATGCAGTCCTGTCTGGCGAGAAGTATACTTTTGG GTCTACTGTTCACTATTCCTGCACAGGAAAGCGTTCCCTTTTAGGCCAGTCATCAAGAACCTGCCAATTGAATGGCCATTGGAGTGGATCACAACCTCAT TGTTCAGGTGATGCTACTGGGACATGTGGCGATCCAGGTACTCCCGGCCATGGCTCTAGACAGGAAAGCAATTTCAGAACTAAAAGTACTGTACGTTATG CTTGTGATACTGGTTACATCCTTCATGGCTCAGAAGAAAGAACATGTTTAGCTAATGGCAGTTGGACCGGAAGGCAGCCAGAGTGCAAAGCTGTGCAGTG TGGTAACCCAGGAACCACAGCCAATGGGAAAGTCTTCCGAATTGATGGCACAACATTTTCTAGTTCAGTCATTTATTCCTGCATGGAGGGATACATCCTT TCTGGACCTTCAGTTAGACAGTGCACAGCCAATGGAACATGGTCTGGAACTTTACCTAACTGTACAATAATCAGTTGTGGAGACCCAGGTATACCAGCCA ATGGACTGAGATATGGAGATGATTATGTGGTTGGACAAAATGTTTCTTACATGTGCCAGCCAGGCTACACGATGGAATTGAATGGCTCCAGAATCAGGAC TTGTACAATTAATGGCACATGGAGTGGAGTAATGCCAACTTGTAGAGCTGTTACCTGCCCAACTCCTCCCCAGATCTCTAATGGAAGGCTGGAAGGAACA AATTTCGACTGGGGCTTTAGTATTAGCTACATCTGTTCTCCAGGCTATGAGCTATCCTTCCCTGCTGTTTTGACCTGTGTAGGGAATGGTACCTGGAGTG GTGAAGTACCGCAGTGCTTACCAAAGTTTTGTGGTGACCCTGGTATACCTGCCCAAGGAAAAAGAGAAGGCAAAAGCTTTATATACCAGTCAGAGGTTTC ATTCAGCTGCAATTTTCCTTTCATATTAGTGGGATCAAGCACCAGAATATGTCAAGCAGATGGCACTTGGAGTGGTTCATCACCTCACTGCATAGAGCCT ACCCAAACCTCTTGTGAAAACCCAGGTGTGCCTCGGCATGGATCTCAGAACAATACATTCGGATTTCAAGTAGGAAGTGTTGTACAGTTCCATTGCAAAA AAGGACACCTTCTCCAAGGGTCTACAACACGCACCTGCCTCCCTGATCTTACGTGGAGTGGGATTCAGCCTGAATGCATACCCCACAGCTGTAAACAGCC AGAAACTCCTGCTCATGCAAATGTCGTAGGGATGGACCTTCCATCTCATGGGTATACACTGATTTATACCTGTCAGCCTGGCTTCTTCTTAGCAGGTGGA ACAGAACATAGAGTGTGTAGATCCGATAACACCTGGACTGGAAAAGTTCCCATTTGTGAAGCTGGTTCTAAAATATTGGTGAAAGATCCTAGACCTGCAC TGGGAACACCCAGCCCAAAGCTAAGTGTTCCTGATGATGTATTTGCCCAAAATTATATATGGAAAGGCTCTTACAATTTCAAAGGAAGGAAACAACCCAT GACCTTAACAGTTACTAGTTTCAATGCTTCCACTGGGAGAGTTAACGCAACACTGAGCAATAGCAACATGGAGCTGCTACTTTCAGGGGTATATAAAAGC CAGGAAGCTCGCCTAATGTTACGCATATATCTTATTAAAGTACCTGCTCATGCTTCTGTGAAGAAAATGAAGGAAGAAAATTGGGCAATGGATGGCTTTG TTTCTGCTGAGCCTGATGGAGCTACTTATGTATTTCAAGGATTTATTCAAGGCAAAGATTATGGACAATTTGGCCTACAAAGACTGGGACTGAATATGTC AGAAGGTTCAAATTCTTCAAATCAACCTCATGGTACAAATAGTAGTTCTGTAGCCATTGCTATTCTTGTGCCTTTTTTTGCACTTATATTTGCAGGATTT GGATTTTATCTTTATAAACAAAGGACTGCACCTAAAACACAGTATACAGGATGTTCAGTTCATGAAAATAACAATGGCCAAGCAGCTTTTGAAAATCCCA TGTATGACACCAACGCAAAGTCAGTGGAAGGGAAGGCGGTACGATTTGATCCCAACTTGAACACGGTTTGCACAATGGTATAACGAGGCAACCTTTGCCT TCTTCAGAAGCTTGGAAATCGACACACAAAACAGTGCACATTTAGTTCACTGCTAAACAAATTAAAGCACACTTTTCAGGACTTGCTGGGTCACCTTTTC CTGAGGAATGATACAGAAGAGTGTTTTTTCATAAACTGGACCATAATTCTTCATGTTTACCATGGAGAGTTTTACAGAAATTTGGCTGCACTCTGAGAGT GCTTACTCACAGTTTATTTGCTTTTTTTAAAAAGGAGATTATTCTAAAATATAAACTTATTTGCATATATTGGAGGAGCATCCACTATCAGTATTTCTGT GCTTTATAAACTATATTAGAGGGACTGGGTTTAAAAAAAAAGATATAGGGTAGAAATAAGAGCTATACTTACAAGAGTCAATAGATCACTGACTTCTCTT TAACTGTCCTGAGCTACATCACGCCCACAAATCTGTCTTTCATACCACTCTATCTGCCATTCATTCTTGTTAAATGAGGCATTGTTTTCTTTATTTAAGA TTGAGTTATGACTTTAAATGTTTATGAGCTAGTTTATGCCTCGGAAGACATAAGGTTTCCCATTCCAATTTGAATCTTTCTATTTCTTTAGCATCATATT GCTCTTCTTCTTTTAGACTGGTTGTCATAGTTTCTGCAAAGGGCAAGTTCATTGTGCTACCCTCCCAATTCCCCCATTATGGAGTAACCAGTATTATTCA GTGAGCTATGGGGTAGTGTTTCACTCCTTGCTTCAATATGGTTTTTTCCTATTTATTTTTATTATTTTTTAATCCCAAATGTGATAGTAGCTTCAGTATG TTTCCTCACCCAAAAACCATTTGGCTGGCAGAAATTATCTAGAAAAATTATTATTTTGCAGTTATCTGAGACACCAAACTTACCATCCTTTATTTTACAA TATTTTTGATCGACCAAATAAAATGTCCTAATAATCTACTCTATTTATATCTACATTTCCTTCCAGCTGAGTCTTCAAATTTAGCATTATTTTGACACTT TTAATTTTCATTTAACAATGGATTAGAAAAATATTTTGGTCTAGCCACTAAACATAATGACTGAAAAAAATTATTATTATAAATCACCAATATAAATTTA TTGCCTACAATTGTGGACTTATCATATTTTTATATATTTTTAAATTTCTGTACCTTTATTGTTAAACACCAAGTTTCACATACAAGAGGTTTCTTTCATT GTCAAATTAAGATATGTATTTGTAAGTTATTGGTGGCTCATTTAAACTGTATCATACAGTAATGCCAGCATTTTTATTTAATAGGTCATCGTCTTCCTTT TATAGCTGTTTTACTTCATTGAATACGATCATGTACCCAGTGTTAACTCTTTGTTGTTGTCCCTTTCAAATATGGATAACTCTGTGAACAGTCTTGACTT TTTGTATCATGAGACAGAGTGCCTAAGAGAAACCCTTGCACCTGGGAGCGCTGCTTGGCTCTATCTCTACAACATTTAATGAATTTCTTGTAAACCACTT TGAGATACATTGTTTTGGAAATTCATACAATTTTCTCAACATGGTACTCTACTGGCAGGATGCAGTTTTAAATTTTATGCCATCAGTTATTTATTCTTGT TTATTCAAATGACTGCAATAACAATGATTCATTCATTAATGTTAAGGCTAATACATTTAAGATCTTGTTTAAACAATGTTTCTTCTGCAACTGGCTACTC CTCTTATATTAATGCATACACTTTTGTAAAGAAGTATATTTTTATGAAAAGAAACTTTGTAAAAGTATGATGTAAATTTTCAGTGCAATGTAAACAAAAT AAAAATGGATAATTGCTTTTGTAAAA

refseq_CSMD3.F2 (forward primer)
refseq_CSMD3.R2 (reverse primer)
Single exon skipping

Frame 0

ETLCPRWRDG*VLVKVAVVSQKHHSLRAVTAHQ QQQQLHCAGLRSRN*ELANNMKGIRKGESRAKES KPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFW NLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPG FPYGYPNGANCTWVIIAEERNRIQIVFQSFALEE EYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTST KSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGN PGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHP QLTCIANSVNTASWDFPVPICRAEDACGGTMRG SSGIISSPSFPNEYHNNADCTWTIVAEPGDTIS LIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPP PIISNKNWLRLHFVTDSNHRYRGFSAPYQGSST LTHTTSTGELEEHNRTTTGAIAVASTPADVTVS SVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDG LSPHPADTQSTRRRPRHAEQIERTKELAVVTHR VKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIK TASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDE DYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKT CGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITA VNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDP RTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESV GSVGFKVNYKEIEKESCGDPGTPLYGIREGDGF SNRDVLRFECQFGFELIGEKSIVCQENNQWSANI PICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNC IWTIISDPGSRIHLSFNDFDLESQFDFLAVKDG DSPESPILGTFTGAEVPSHLTSNSHILRLEFQAD HSMSGRGFNITYNTFGHNECPDPGIPINARRFG DNFQLGSSISVICEEGFIKTQGTETITCILMDG KVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGY YKDSLNCEWVIEAEPGHSIKITFERFQTELNYD VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNF IYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPG IPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEP LLCEKNHWWSHPLPTCDALCGGDVRGPSGTILS PGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHL EDHHDYLLITENGSFTQPLARLTGSDLPPTINA GLYGNFRAQLRFISDFSISYEGFNITFSEYNLE PCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRL EGTSEIICLGGGRRVWSAPLPRCVAECGASATN NEGILLSPNYPLNYENNHECIYSIQVQAGKGIN ISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGAS MRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYT SFELSHCEDPGIPQFGYKISDQGHFAGSTIIYG CNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAEC GGRFKGESSGRILSPGYPFPYDNNLRCMWMIEV DPGNIVSLQFLAFDTEASHDILRVWDGPPENDM LLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKS GFAIQFSSSVATACRDPGVPMNGTRNGDGREPG DTVVFQCDPGYELQGEERITCIQVENRYFWQPS PPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDC DWTITVNADYVISLAFISFSIEPNYDFLYIYDG PDSNSPLIGSFQDSKLPERIESSSNTMHLAFRS DGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLG MDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDG RPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPK NYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDV VEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQ ITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSS VPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSI AIRCETVPNSLAQWNDSLPTCIVPCGGILTKRK GTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQ VVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTI PHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAI GLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQ GYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGA MSDFSGVILSPGFPGNYPSSLDCTWTINLPIGF GVHLQFVNFSTETIHDYLEVRSGSSETSTVIGR LSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHI VYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTIS FECFPGYTLIGNSALTCLHGVSRNWNHPLPRCE ALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVR VPPGNGIYINFTVLQTEPIYDFITVWDGPDQNS PQIGQFSGNTALESVYSTSNQILIKFHSDFTTS GFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFE IGDIIRYQCLPGFTLVGNAILTCRLGERLQMDG APPVCQVLCPANELRLDSTGVILSPGYPDSYPN LQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQV YDGPNIQSPVLISLSGDYSSAFNITSNGHEVFL QWSADHGNNKKGFRIRYIAFYCSTPESPPHGYI ISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSS YGYHAWDAPVPACQAISCGIPKAPTNGGILTTD YLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTW SNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSH YEYKTKVVFSCDPGYHGLGPASIECLPNGTWSW RNERPYCQIISCGELPTPPNGNKIGTQTSYGST AIFTCDLGFMLVGSAVRECLSSGLWSESETRCLA GHCGIPELIVNGQVIGENYGYRDTVVYQCNPGF RLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGS PIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQ CQANRQWSHPPPMCKVVNCSDPGIPANSKRESK IEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPN GQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFG STVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPH CSGDATGTCGDPGTPGHGSRQESNFRTKSTVRY ACDTGYILHGSEERTCLANGSWTGRQPECKAVQC GNPGTTANGKVFRIDGTTFSSSVIYSCMEGYIL SGPSVRQCTANGTWSGTLPNCTIISCGDPGIPA NGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRT CTINGTWSGVMPTCRAVTCPTPPQISNGRLEGT NFDWGFSISYICSPGYELSFPAVLTCVGNGTWS GEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVS FSCNFPFILVGSSTRICQADGTWSGSSPHCIEP TQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCK KGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQP ETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGG TEHRVCRSDNTWTGKVPICEAGSKILVKDPRPA LGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPM TLTVTSFNASTGRVNATLSNSNMELLLSGVYKS QEARLMLRIYLIKVPAHASVKKMKEENWAMDGF VSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMS EGSNSSNQPHGTNSSSVAIAILVPFFALIFAGF GFYLYKQRTAPKTQYTGCSVHENNNGQAAFENP MYDTNAKSVEGKAVRFDPNLNTVCTMV*RGNLCL LQKLGNRHTKQCTFSSLLNKLKHTFQDLLGHLF LRNDTEECFFINWTIILHVYHGEFYRNLAAL*E CLLTVYLLFLKRRLF*NINLFAYIGGASTISISV LYKLY*RDWV*KKRYRVEIRAILTRVNRSLTSL *LS*ATSRPQICLSYHSICHSFLLNEALFSLFK IEL*L*MFMS*FMPRKT*GFPFQFESFYFFSIIL LFFF*TGCHSFCKGQVHCATLPIPPLWSNQYYS VSYGVVFHSLLQYGFFLFIFIIF*SQM***LQY VSSPKNHLAGRNYLEKLLFCSYLRHQTYHPLFYN IFDRPNKMS**STLFISTFPSS*VFKFSIILTL LIFI*QWIRKIFWSSH*T**LKKIIIINHQYKF IAYNCGLIIFLYIFKFLYLYC*TPSFTYKRFLSL SN*DMYL*VIGGSFKLYHTVMPAFLFNRSSSSF YSCFTSLNTIMYPVLTLCCCPFQIWITL*TVLT FCIMRQSA*EKPLHLGALLGSISTTFNEFLVNHF EIHCFGNSYNFLNMVLYWQDAVLNFMPSVIYSC LFK*LQ*Q*FIH*C*G*YI*DLV*TMFLLQLAT PLILMHTLL*RSIFL*KETL*KYDVNFQCNVNKI KMDNCFCK

Frame 1

RLCAPVGEMVESSSRLLWYPRNTIHSEL*PRTN NSNNSTAPG*GAGIRSSRII*KGSAKGKAEQRN PNPGSLASEDALNVAA*TSS**RKWGLKVDLRFG TSSFY*RCLV*KDLFIHVVEL*KDLMAL*KALV FHMDIQMVQTAHG***QKNEIEYKLFFSHLL*K KNTTTYHYMMDILILQTLGQG*QDSICHLQ*QVP NLCSHYV*PVILQLVLMDLRYITKNCRVALVEI LVFHPKVYYMAQDSTSGTRSATAV*LDTSLMAT LSSPA*PIQLIQLRGIFLFLSVELKMLVEEQ*ED PVASYPALVFLMSTITMLIALGPL*QSLGTQFH SYLLIFKWKRNMIT*K*KVLSHLPYGYLE*IYH HQLSATKTGSDCILLQTAIIDTVDLVLPIKVLLH *PTLPPLVS*RSITGLPLVLLLLLAHLQMLLYP VLQLSPSIDFPRNSECKLRVSEIQVWTPTRPRT GSLLIQQIHKVPGEDQDMLNR*KELKSLQLLLIE *KRP*ILNLEDLNCFQGKTTATSFLS*MREVLK QLPIYAQIQENQKMGRESDQILALDQLCSSLVM KIMSYRAQRASPVNG*LKFLLLGVITGLCVK*KR VALIFKDQVVPLHLPTFRSSMTAMHNVSGSSQQ *IQIRLSR*ILKNLIWRLAMIP*QLAMGAKLEI LGQCSKC*LEALYQT***A*VAKCGCTFKRTKVL DLLVSRLTTKKLRKKVVVILVHPYMELEKAMDF LIVMF*GLNASLGLN*LERNPLFVKRITNGLQT YPSVSFPACLTLLHQWEQFFLLITQKGMEII*IA SGR*SLIQGAGYIFLSMTLTWNPSLISLLLKMV TLQNPQFLEPLLGLRCLPILLVIVTYCDWNFRL TTQCQDVALTSLTTHLDIMNALILEYQSMHGGLG TTFN*EVQFQLFVKKDLLKPREQKQLHVFLWME K*CGVD*FQNVEPHVVAIFQLPVE*FSHQDGQD TTKTL*IVSG*LKLNLDTLSKLHLKDFRLN*IMM FWKFMMGQIFCHPCLDLTMAPKCPSFYLVAVIL YTFYLQQTTVVPIMVSRFIMKVLQ*TRILVWTL AYLYMAVAMVMISPLALLFHLVVIQDTG*VMKSP FYAKKTTGGVIHFQPVMHYVEEMLEGLVEQSYH LVTRNFIQIL*IVHGLLM*PMEKVCSSTSTLFI WKTIMTTY*SQRMAVLPNHWHA*LVQIFLQQSML VSMEISGLNCVSFQIFQYHMKDLT*HSLNITLN LVKILAFLNMVVESGSTLGLVTL*PSHALRVID WKEHQRSSVLVVADECGVHLCQGVWLNVVHLQRI MKEFCCLQIIHSTMKTTMNAFIVFRFKQERESI FQPEHFI*HKEMFLRFMMEKIKRLIY*VLLLVH LCAD*HLVVLQINSG*NLIPILKGQMKAFNLCIP VLNSHTVKILAFHNLDTRSVTKATLLVAPSFMD AIQATLSTEVAFSSA*QGREGHGTILCLPVLLN VEVVLKENHQEESYLLAILFHMTITCVACG*LR* ILEILSACSFLLLIRKHHMIYSESGTVHQKMIC F*RKLVDLLFLKEFIAPSI**PSSLTRIFILAN LDLQFSFQVLLPLRVVTQGSP*MGLEMGMEENLG TLLFFNVTQDMNFKERKE*PAFR*KIGTSGSPA HQSV*HPVEAI*QDLQALFFHQTSLIHIRIAET VTGLSPSMQTMLSPWRSSVLA*NQTMTSSISMMD QTVIAH*LEVFKTASYQRE*KAAQIQCIWLFGV MDLLVTLDFI*NTKQNCESPALIQAI**MAPDL EWIIN*GQQSPITVMLVMFFKVIQHSPVSWEMME DLDGIEPCQVVMRPVEVVQQVQKALFYHQTIQK ITVWDIIVFIL*QFQRSLWCLASLYFSRHHSTM LLRCMMGQLSNLLCYLPSQDPIQENHFH*VQVIR SQFDLLQLDQ*QLRDFTLFTKLFLEQVLHNAVL CLNQDSEEELAMNLQSVHRFFLIVIQDIFSMDP *QLGVKQCPILWPSGMIPYLLVLCPVVEF*LSAK GLFCHLDTLSLMTTI*IVCGRSQCQRELAFKCK LLALLQNIIGILWTFMMGETTMLQDLEAIQEQQ YPIF*IVRLIICI*IFNQTSVFLLQDFILNTQQL VWIPVLNHKLLAVELKLETDIWLEM*YPFSVIK DILFRVTLTLHVCQDL*EDGIIQSQFV*LSVVV LCQTSVV*SSVLGFLETIPAV*IAHGQ*IYP*VL VYISSL*IFLQKPYMIIWKYEVDPQKLVLLLAG LVVLKYHLPYSAPPMKPAYIFTVTIHKTNKGFI LYTKPISCKAVLIHARFEMVL*LVMILLWVKPFH LNVSQDTH*LEIQLSHAFTESVVIGIIHFQGVK LFVVGI*LQ*MAPFILLGILMNIQTFKIVFGL* EYPLGMASTSILLSFKQNQYMISLLYGMDQTKIH LRSVSSVAIPLWNQSTVLQIRF*SNSTVISQQV AFLCSVITPIN*GCANLHHLCPMLKF*RKMMNL K*VILLGISVFQDLL*LVMQF*RAD*ENDCRWME HLQFVKCSVLPMNYG*ILLESY*ALDILTVTQI FKCVHGAFQWKRVIISPCL*NSSRQKRNLMFFR CMMDQIFKVQCLFPSVGIIHLLLI*QAMVMKYFF SGQQIMAITKKASG*DI*LSTVVHQNPHLMDIL SVRQVGSLTVWSVGPVIEDSDLLEKAVLCAESL PMGIMHGMRQSLPVKQFPVGFLKLQQMEEY*QQT IW*ERELPIFVMMDIDCHPKNSLQLYANQMEHG AIITRPLAVLLLHVQASIPLSWNMEDGEL*MAP IMNTKPK*FSAVTLVIMD*VLPPSNVFLMVLGVG EMKDHIAKLFPVENYLHLQMEIRLELKLHMAQQ LSLPATWDSCLWALL*GNAFPQVFGVNLKPDA* RVIVEFQN*L*MVKSLEKIMDIETQLYINVILVF D*LVLQ*GYVNRITIGLVSSHPVCLLAVVTLVV QFMEEQVEMGSTLMMW*HSHAILGILCKGQQRH SARPTDSGAILHLCAKWSTVLILEFQPILKEKVK *NMEILLTALWYSMTAILDIFYLDLQF*YVNQM DNGTNLYQNVS*LTVDTLAFLLMQSCLARSILL GLLFTIPAQESVPF*ASHQEPAN*MAIGVDHNLI VQVMLLGHVAIQVLPAMALDRKAISELKVLYVM LVILVTSFMAQKKEHV*LMAVGPEGSQSAKLCS VVTQEPQPMGKSSELMAQHFLVQSFIPAWRDTSF LDLQLDSAQPMEHGLELYLTVQ*SVVETQVYQP MD*DMEMIMWLDKMFLTCASQATRWN*MAPESG LVQLMAHGVE*CQLVELLPAQLLPRSLMEGWKEQ ISTGALVLATSVLQAMSYPSLLF*PV*GMVPGV VKYRSAYQSFVVTLVYLPKEKEKAKALYTSQRF HSAAIFLSY*WDQAPEYVKQMALGVVHHLTA*SL PKPLVKTQVCLGMDLRTIHSDFK*EVLYSSIAK KDTFSKGLQHAPASLILRGVGFSLNAYPTAVNS QKLLLMQMS*GWTFHLMGIH*FIPVSLASS*QVE QNIECVDPITPGLEKFPFVKLVLKYW*KILDLH WEHPAQS*VFLMMYLPKIIYGKALTISKEGNNP *P*QLLVSMLPLGELTQH*AIATWSCYFQGYIKA RKLA*CYAYILLKYLLMLL*RK*RKKIGQWMAL FLLSLMELLMYFKDLFKAKIMDNLAYKDWD*IC QKVQILQINLMVQIVVL*PLLFLCLFLHLYLQDL DFIFINKGLHLKHSIQDVQFMKITMAKQLLKIP CMTPTQSQWKGRRYDLIPT*TRFAQWYNEATFA FFRSLEIDTQNSAHLVHC*TN*STLFRTCWVTFS *GMIQKSVFS*TGP*FFMFTMESFTEIWLHSES AYSQFICFF*KGDYSKI*TYLHILEEHPLSVFL CFINYIRGTGFKKKDIG*K*ELYLQESIDH*LLF NCPELHHAHKSVFHTTLSAIHSC*MRHCFLYLR LSYDFKCL*ASLCLGRHKVSHSNLNLSISLASY CSSSFRLVVIVSAKGKFIVLPSQFPHYGVTSIIQ *AMG*CFTPCFNMVFSYLFLLFFNPKCDSSFSM FPHPKTIWLAEII*KNYYFAVI*DTKLTILYFT IFLIDQIKCPNNLLYLYLHFLPAESSNLALF*HF *FSFNNGLEKYFGLATKHND*KKLLL*ITNINL LPTIVDLSYFYIFLNFCTFIVKHQVSHTRGFFH CQIKICICKLLVAHLNCIIQ*CQHFYLIGHRLPF IAVLLH*IRSCTQC*LFVVVPFKYG*LCEQS*L FVS*DRVPKRNPCTWERCLALSLQHLMNFL*TT LRYIVLEIHTIFSTWYSTGRMQF*ILCHQLFILV YSNDCNNNDSFINVKANTFKILFKQCFFCNWLL LLY*CIHFCKEVYFYEKKLCKSMM*IFSAM*TK *KWIIAFVK

Frame 2

DFVPPLERWLSPRQGCCGIPETPFTPSCDRAPT TATTPLRRAEEQELGARE*YERDPQRGKPSKGI QTLGAWQAKMR*MWPPRLHPDEENGD*KWIYVL EPRLFIDGVLCERIYLYMWWNFKRT*WHYRKPWF SIWISKWCKLHMGNNSRRTK*NTNCFSVICSRR RIRLLIII*WTSSSYKL*DKVNRIPSATSSDKY QICVLTTFDQ*FCS*CSWI*GILRRIAE*LLWKS WCSTQRCIIWHKIRRRGQDPLQLCNWIHP*WPP SAHLHSQFS*YSFVGFSCSYL*S*RCLWRNNER IQWHHIQP*FS**VP*QC*LHLDHCSRAWGHNFT HIY*FSNGREI*LLRNRRF*ATYHMVIWNEYTT TNYQQQKLAQTAFCYRQQSSIPWI*CSLSRFFY IDPHYLHW*VRGA*QDYHWCYCCC*HTCRCYCIQ CYSCHHP*TFRGTASASYESQKFRSGPQHVQGR ALSSSSRYTKYQEKTKTC*TDRKN*RACSCYS* SEKGHRF*I*RI*IVSRERQQQQVFYLK*GRY*N SFQFMPRSRRTRKWEENRIRF*PWINCAVLL** RLCPTGRKEHHLSTDS*SFCCLE*SQACV*SEN VWL*SSRTKWYLYISQLSVPV*QQCTMCLGHHSS EYK*GYPDKF*RI*SGDWL*YLDNWRWGRSWRS *DSAPSADWKLCTRLDSEHE*PNVAAPSNGRKC WICWFQG*LQRN*ERKLW*SWYTLIWN*RRRWIF *S*CFKV*MPVWV*INWREIHCLSRE*PMVCKH THLYLSLPV*LYCTNGNSSFS*LPRRVWK*FKL HLDDNL*SREPDTSFFQ*L*PGIPV*FPCC*RW* LSRIPNSWNLYWG*GAFPSY***SHTAIGISG* PLNVRTWL*HHLQHIWT**MP*SWNTNQCTAVW GQLSIRKFNFSYL*RRIY*NPGNRNNYMYSYGWK SNVEWTDSKMWSPMWWPFFSSQWSDSLTRMARI LQRLFEL*VGD*S*TWTLYQNYI*KISD*TEL* CSGSS*WAKSSVTLAWILQWHPSAPVSI**Q*FY IPSIYNRQQSFQ*WFQDSL*KCYSEHVFLFGPW HTCTWPSLWS*FLHWLYCFI*L*FRIQVES*RA PSMRKKPLVESSTSNL*CIMWRRC*RA*WNNLIT WLPGILSKFSELYMDC*CNPWKRCAVQLPHFSF GRPS*LLTDHREWQFYPTTGTPDWFRSSSNNQC WSLWKFQGSIAFHFRFFNII*RI*HNIL*I*P*T L*RSWHSSIW*SNRVQLWDW*HSDLLMLFGLST GRNIRDHLSWWWPTSVECTSAKVCG*MWCICNE **RNFAVSKLSTQL*KQP*MHL*YSGSSRKGNQY FSQNISFSTRRCS*DL*WKR*NDSSTRCFYWCI YARTDT**YFKSTLARI*FRY*RDR*RLSTCVY QF*TLTL*RSWHSTIWIQDQ*PRPLCW*HHHLWM QSRLHSPRK*PSQVHDRGEKGMGLSSAFLYC*M WRSF*RRIIRKNLISWLSFSI*Q*PALHVDD*G RSWKYCQLAVSCF*YGSIT*YTPSLGRSTRK*YA FKGN*WISYS*RNS*HPQYSNHPV*HGFLY*QI WICNSVFKFCCHCVS*PRGPHEWDSKWGWKRTW GHCCFSM*PRI*TSRRGKNNLHSGRKSVLLAAQP TSLYSTLWRQFNRIFRLYSFTKLPSSISA*QRL *LDYHRQCRLCYLLGVHQF*HRTKL*LPLYL*W TRQ**PTDWKFSRQQVTRENRKQLKYNAFGFSE* WIC*LHWISSRIQSKTARVLL*SRQYNEWHQTW NGL*IRVNSHLLL*CWLCSSRLFNTHLYHGR*W KTWME*SLAKLSCALWKSFNRFRRHCSITKLSKK LQCGT*LCLFYSSSKGVCGVWPVCIFPDITPRC C*GV*WANSAIFSVIFPLRIPFRRITSTEFR*S DHNSIYFSWTNNS*GISLCLPSCS*NKFYTMQFC A*TKIRKKNWQ*ICSRFIGSF*L*SRIYSPWIH SN*V*NSAQFFGPVE*FLTYLYCALWWNFN*AQ RDYFVTWIP*AL*QQSELCVEDHSARGSWHSSAS C*LCYRT*LGFSGLL*WGRQQCSKTWKLFRNNN TPSFE*YV**SVSKFSIRHQCFCCRISS*IHSN WFGFLS*TTNS*QWN*NWRQIYGWRCSILSV*SR IFSSGSLSHYMYARTCKKMELSNPNLFSSVWWC YVRLQWCDPQSWVSWKLSQQFRLHMDNKSTHRF WCTSPVCKFFYRNHT*LFGSTKWILRN*YCYWPA *WSSNTIFLIQHHP*NQLIFSQ*LFTKQTRVSY CIPSLSVAKLS*STPVSKWFCNW**FYCGSNHF I*MFPRIHINWKFSSHMPSRSQS*LESSTSKV*S SLWWEYNCNEWHHLFSWVS**ISKLSRLFLACK STPWEWHLHQFYCPSNRTNI*FHYCMGWTRPKF TSDRSVQWQYRFGISLQYFKSDSNQIPQ*FHNKW LFCAQLSRLSTKGVPTSTTCAQC*NFDGR**I* NR*YY*VSVSSRIYFSW*CNSDVQIRRTTADGW STSSLSSALSCQ*ITARFYWSHIEPWIS*QLPKS SNVCMEHFSGKGL*YHHVCRILPDRKGI*CSSG V*WTKYSKSSAYFPQWGLFICF*YNKQWS*SIS SVVSRSWQ*QKRLPDKIYSFLL*YTRIPTSWIYY QSDRWAA*QCGPLGL*SRIPTCWKKQCCVQKVF LWVSCMGCASPCLSSNFLWDS*SSNKWRNTNNR LFGRNASYLFL**WISIVIQRTHYSCMPIRWNME QS*QDPSLCCCYMSKHQFLYLGTWKMANCEWLP L*IQNQSSFQL*PWLSWTRSCLHRMSS*WYLEL EK*KTILPNYFLWRTTYTSKWK*DWNSNFIWLNS YLYLRLGIHACGLCCKGMPFLRSLE*I*NQMPS GSLWNSRTDCEWSSHWRKLWI*RHSCISM*SWF SIDWFFSEDMSTGSQLVWSAPILCAC*LWSPW*S NLWKNKWKWVQL**CGNILMQYWVSYARANKGT VPGQQTVEPSSTYVQSGQLF*SWNSSQF*KRK* NRTWKFYLRHCGIL*LQSWIFFIWIFSFDMSTKW TMGQTFTRMYHD*LWTPWRSS*CSPVWREVYFW VYCSLFLHRKAFPFRPVIKNLPIEWPLEWITTS LFR*CYWDMWRSRYSRPWL*TGKQFQN*KYCTLC L*YWLHPSWLRRKNMFS*WQLDRKAARVQSCAV W*PRNHSQWESLPN*WHNIF*FSHLFLHGGIHP FWTFS*TVHSQWNMVWNFT*LYNNQLWRPRYTSQ WTEIWR*LCGWTKCFLHVPARLHDGIEWLQNQD LYN*WHMEWSNANL*SCYLPNSSPDL*WKAGRN KFRLGL*Y*LHLFSRL*AILPCCFDLCREWYLEW *STAVLTKVLW*PWYTCPRKKRRQKLYIPVRGF IQLQFSFHISGIKHQNMSSRWHLEWFITSLHRA YPNLL*KPRCASAWISEQYIRISSRKCCTVPLQK RTPSPRVYNTHLPP*SYVEWDSA*MHTPQL*TA RNSCSCKCRRDGPSISWVYTDLYLSAWLLLSRW NRT*SV*IR*HLDWKSSHL*SWF*NIGERS*TCT GNTQPKAKCS**CICPKLYMERLLQFQRKETTH DLNSY*FQCFHWES*RNTEQ*QHGAATFRGI*K PGSSPNVTHISY*STCSCFCEENEGRKLGNGWLC FC*A*WSYLCISRIYSRQRLWTIWPTKTGTEYV RRFKFFKSTSWYK**FCSHCYSCAFFCTYICRI WILSL*TKDCT*NTVYRMFSS*K*QWPSSF*KSH V*HQRKVSGREGGTI*SQLEHGLHNGITRQPLP SSEAWKSTHKTVHI*FTAKQIKAHFSGLAGSPF PEE*YRRVFFHKLDHNSSCLPWRVLQKFGCTLRV LTHSLFAFFKKEIILKYKLICIYWRSIHYQYFC AL*TILEGLGLKKKI*GRNKSYTYKSQ*ITDFS LTVLSYITPTNLSFIPLYLPFILVK*GIVFFI*D *VMTLNVYELVYASEDIRFPIPI*IFLFL*HHI ALLLLDWLS*FLQRASSLCYPPNSPIME*PVLF SELWGSVSLLASIWFFPIYFYYFLIPNVIVASVC FLTQKPFGWQKLSRKIIILQLSETPNLPSFILQ YF*STK*NVLIIYSIYIYISFQLSLQI*HYFDT FNFHLTMD*KNILV*PLNIMTEKNYYYKSPI*IY CLQLWTYHIFIYF*ISVPLLLNTKFHIQEVSFI VKLRYVFVSYWWLI*TVSYSNASIFI**VIVFL L*LFYFIEYDHVPSVNSLLLSLSNMDNSVNSLDF LYHETECLRETLAPGSAAWLYLYNI**ISCKPL *DTLFWKFIQFSQHGTLLAGCSFKFYAISYLFL FIQMTAITMIHSLMLRLIHLRSCLNNVSSATGYS SYINAYTFVKKYIFMKRNFVKV*CKFSVQCKQN KNG*LLL*

Sequence NM_198124

TACACCCCTCGGCCCTTTGGAGGACCGGAGAGCCGGACGACGCCGCAGCCCTTGGGGGAGTCCAGCGCCAGCTGGCGAAAAGAAGCTTCATCTTCCAGAT CATCCGGGAAAGGGGCAGAGGTGGCCGGTTGTTGCGACTCATAAACAACCTCTTCAGCACAACCCGGTTGAATGTGGAGTTGGTTCCTTTGCTGGAAACC TGTACAGCTTGACCGACAGACAGCCTCAGGATTTATTTATACATGTGGTGGAACTTTAAAAGGACTTAATGGCACTATAGAAAGCCCTGGTTTTCCATAT GGATATCCAAATGGTGCAAACTGCACATGGGTAATAATAGCAGAAGAACGAAATAGAATACAAATTGTTTTTCAGTCATTTGCTCTAGAAGAAGAATACG ACTACTTATCATTATATGATGGACATCCTCATCCTACAAACTTTAGGACAAGGTTAACAGGATTCCATCTGCCACCTCCAGTGACAAGTACCAAATCTGT GTTCTCACTACGTTTGACCAGTGATTTTGCAGTTAGTGCTCATGGATTTAAGGTATATTACGAAGAATTGCAGAGTAGCTCTTGTGGAAATCCTGGTGTT CCACCCAAAGGTGTATTATATGGCACAAGATTCGACGTCGGGGACAAGATCCGCTACAGCTGTGTAACTGGATACATCCTTGATGGCCACCCTCAGCTCA CCTGCATAGCCAATTCAGTTAATACAGCTTCGTGGGATTTTCCTGTTCCTATCTGTAGAGCTGAAGATGCTTGTGGAGGAACAATGAGAGGATCCAGTGG CATCATATCCAGCCCTAGTTTTCCTAATGAGTACCATAACAATGCTGATTGCACTTGGACCATTGTAGCAGAGCCTGGGGACACAATTTCACTCATATTT ACTGATTTTCAAATGGAAGAGAAATATGATTACTTAGAAATAGAAGGTTCTGAGCCACCTACCATATGGTTATCTGGAATGAATATACCACCACCAATTA TCAGCAACAAAAACTGGCTCAGACTGCATTTTGTTACAGACAGCAATCATCGATACCGTGGATTTAGTGCTCCCTATCAAGGTTCTTCTACATTGACCCA CACTACCTCCACTGGTGAGTTAGAGGAGCATAACAGGACTACCACTGGTGCTATTGCTGTTGCTAGCACACCTGCAGATGTTACTGTATCCAGTGTTACA GCTGTCACCATCCATAGACTTTCCGAGGAACAGCGAGTGCAAGTTACGAGTCTCAGAAATTCAGGTCTGGACCCCAACACGTCCAAGGACGGGCTCTCTC CTCATCCAGCAGATACACAAAGTACCAGGAGAAGACCAAGACATGCTGAACAGATAGAAAGAACTAAAGAGCTTGCAGTTGTTACTCATAGAGTGAAAAA GGCCATAGATTTTAAATCTAGAGGATTTAAATTGTTTCCAGGGAAAGACAACAGCAACAAGTTTTCTATCTTAAATGAGGGAGGTATTAAAACAGCTTCC AATTTATGCCCAGATCCAGGAGAACCAGAAAATGGGAAGAGAATCGGATCAGATTTTAGCCTTGGATCAACTGTGCAGTTCTCTTGTGATGAAGATTATG TCCTACAGGGCGCAAAGAGCATCACCTGTCAACGGATAGCTGAAGTTTTTGCTGCTTGGAGTGATCACAGGCCTGTGTGTAAAGTGAAAACGTGTGGCTC TAATCTTCAAGGACCAAGTGGTACCTTTACATCTCCCAACTTTCCGTTCCAGTATGACAGCAATGCACAATGTGTCTGGGTCATCACAGCAGTGAATACA AATAAGGTTATCCAGATAAATTTTGAAGAATTTGATCTGGAGATTGGCTATGATACCTTGACAATTGGCGATGGGGGCGAAGTTGGAGATCCTAGGACAG TGCTCCAAGTGCTGACTGGAAGCTTTGTACCAGACTTGATAGTGAGCATGAGTAGCCAAATGTGGCTGCACCTTCAAACGGACGAAAGTGTTGGATCTGT TGGTTTCAAGGTTAACTACAAAGAAATTGAGAAAGAAAGTTGTGGTGATCCTGGTACACCCTTATATGGAATTAGAGAAGGCGATGGATTTTCTAATCGT GATGTTTTAAGGTTTGAATGCCAGTTTGGGTTTGAATTAATTGGAGAGAAATCCATTGTTTGTCAAGAGAATAACCAATGGTCTGCAAACATACCCATCT GTATCTTTCCCTGCCTGTCTAACTTTACTGCACCAATGGGAACAGTTCTTTCTCCTGATTACCCAGAAGGGTATGGAAATAATTTAAATTGCATCTGGAC GATAATCTCTGATCCAGGGAGCCGGATACATCTTTCTTTCAATGACTTTGACCTGGAATCCCAGTTTGATTTCCTTGCTGTTAAAGATGGTGACTCTCCA GAATCCCCAATTCTTGGAACCTTTACTGGGGCTGAGGTGCCTTCCCATCTTACTAGTAATAGTCACATACTGCGATTGGAATTTCAGGCTGACCACTCAA TGTCAGGACGTGGCTTTAACATCACTTACAACACATTTGGACATAATGAATGCCCTGATCCTGGAATACCAATCAATGCACGGCGGTTTGGGGACAACTT TCAATTAGGAAGTTCAATTTCAGTTATTTGTGAAGAAGGATTTATTAAAACCCAGGGAACAGAAACAATTACATGTATTCTTATGGATGGAAAAGTAATG TGGAGTGGACTGATTCCAAAATGTGGAGCCCCATGTGGTGGCCATTTTTCAGCTCCCAGTGGAGTGATTCTCTCACCAGGATGGCCAGGATACTACAAAG ACTCTTTGAATTGTGAGTGGGTGATTGAAGCTGAACCTGGACACTCTATCAAAATTACATTTGAAAGATTTCAGACTGAACTGAATTATGATGTTCTGGA AGTTCATGATGGGCCAAATCTTCTGTCACCCTTGCTTGGATCTTACAATGGCACCCAAGTGCCCCAGTTTCTATTTAGTAGCAGTAATTTTATATACCTT CTATTTACAACAGACAACAGTCGTTCCAATAATGGTTTCAAGATTCATTATGAAAGTGTTACAGTGAACACGTATTCTTGTTTGGACCCTGGCATACCTG TACATGGCCGTCGCTATGGTCATGATTTCTCCATTGGCTCTACTGTTTCATTTAGTTGTGATTCAGGATACAGGTTGAGTCATGAAGAGCCCCTTCTATG CGAAAAAAACCACTGGTGGAGTCATCCACTTCCAACCTGTGATGCATTATGTGGAGGAGATGTTAGAGGGCCTAGTGGAACAATCTTATCACCTGGTTAC CCGGAATTTTATCCAAATTCTCTGAATTGTACATGGACTGTTGATGTAACCCATGGAAAAGGTGTGCAGTTCAACTTCCACACTTTTCATTTGGAAGACC ATCATGACTACTTACTGATCACAGAGAATGGCAGTTTTACCCAACCACTGGCACGCCTGACTGGTTCAGATCTTCCTCCAACAATCAATGCTGGTCTCTA TGGAAATTTCAGGGCTCAATTGCGTTTCATTTCAGATTTTTCAATATCATATGAAGGATTTAACATAACATTCTCTGAATATAACCTTGAACCTTGTGAA GATCCTGGCATTCCTCAATATGGTAGTCGAATCGGGTTCAACTTTGGGATTGGTGACACTCTGACCTTCTCATGCTCTTCGGGTTATCGACTGGAAGGAA CATCAGAGATCATCTGTCTTGGTGGTGGCCGACGAGTGTGGAGTGCACCTCTGCCAAGGTGTGTGGCTGAATGTGGTGCATCTGCAACGAATAATGAAGG AATTTTGCTGTCTCCAAATTATCCACTCAACTATGAAAACAACCATGAATGCATTTATAGTATTCAGGTTCAAGCAGGAAAGGGAATCAATATTTCAGCC AGAACATTTCATTTAGCACAAGGAGATGTTCTTAAGATTTATGATGGAAAAGATAAAACGACTCATCTACTAGGTGCTTTTACTGGTGCATCTATGCGCG GACTGACACTTAGTAGTACTTCAAATCAACTCTGGCTAGAATTTAATTCCGATACTGAAGGGACAGATGAAGGCTTTCAACTTGTGTATACCAGTTTTGA ACTCTCACACTGTGAAGATCCTGGCATTCCACAATTTGGATACAAGATCAGTGACCAAGGCCACTTTGCTGGTAGCACCATCATTTATGGATGCAATCCA GGCTACACTCTCCACGGAAGTAGCCTTCTCAAGTGCATGACAGGGGAGAGAAGGGCATGGGACTATCCTCTGCCTTCCTGTATTGCTGAATGTGGAGGTC GTTTTAAAGGAGAATCATCAGGAAGAATCTTATCTCCTGGCTATCCTTTTCCATATGACAATAACCTGCGTTGCATGTGGATGATTGAGGTAGATCCTGG AAATATTGTCAGCTTGCAGTTTCTTGCTTTTGATACGGAAGCATCACATGATATACTCCGAGTCTGGGACGGTCCACCAGAAAATGATATGCTTTTAAAG GAAATTAGTGGATCTCTTATTCCTGAAGGAATTCATAGCACCCTCAATATAGTAACCATCCAGTTTGACACGGATTTTTATATTAGCAAATCTGGATTTG CAATTCAGTTTTCAAGTTCTGTTGCCACTGCGTGTCGTGACCCAGGGGTCCCCATGAATGGGACTCGAAATGGGGATGGAAGAGAACCTGGGGACACTGT TGTTTTTCAATGTGACCCAGGATATGAACTTCAAGGAGAGGAAAGAATAACCTGCATTCAGGTAGAAAATCGGTACTTCTGGCAGCCCAGCCCACCAGTC TGTATAGCACCCTGTGGAGGCAATTTAACAGGATCTTCAGGCTTTATTCTTTCACCAAACTTCCCTCATCCATATCCGCATAGCAGAGACTGTGACTGGA CTATCACCGTCAATGCAGACTATGTTATCTCCTTGGCGTTCATCAGTTTTAGCATAGAACCAAACTATGACTTCCTCTATATCTATGATGGACCAGACAG TAATAGCCCACTGATTGGAAGTTTTCAAGACAGCAAGTTACCAGAGAGAATAGAAAGCAGCTCAAATACAATGCATTTGGCTTTTCGGAGTGATGGATCT GTTAGTTACACTGGATTTCATCTAGAATACAAAGCAAAACTGCGAGAGTCCTGCTTTGATCCAGGCAATATAATGAATGGCACCAGACTTGGAATGGATT ATAAATTAGGGTCAACAGTCACCTATTACTGTGATGCTGGTTATGTTCTTCAAGGTTATTCAACACTCACCTGTATCATGGGAGATGATGGAAGACCTGG ATGGAATAGAGCCTTGCCAAGTTGTCATGCGCCCTGTGGAAGTCGTTCAACAGGTTCAGAAGGCACTGTTCTATCACCAAACTATCCAAAAAATTACAGT GTGGGACATAATTGTGTTTATTCTATAGCAGTTCCAAAGGAGTTTGTGGTGTTTGGCCAGTTTGTATTTTTCCAGACATCACTCCACGATGTTGTTGAGG TGTATGATGGGCCAACTCAGCAATCTTCTCTGTTATCTTCCCTCTCAGGATCCCATTCAGGAGAATCACTTCCACTGAGTTCAGGTAATCAGATCACAAT TCGATTTACTTCAGTTGGACCAATAACAGCTAAGGGATTTCACTTTGTTTACCAAGCTGTTCCTAGAACAAGTTCTACACAATGCAGTTCTGTGCCTGAA CCAAGATTCGGAAGAAGAATTGGCAATGAATTTGCAGTCGGTTCATCGGTTCTTTTTGATTGTAATCCAGGATATATTCTCCATGGATCCATAGCAATTA GGTGTGAAACAGTGCCCAATTCTTTGGCCCAGTGGAATGATTCCTTACCTACTTGTATTGTGCCCTGTGGTGGAATTTTAACTAAGCGCAAAGGGACTAT TTTGTCACCTGGATACCCTGAGCCTTATGACAACAATCTGAATTGTGTGTGGAAGATCACAGTGCCAGAGGGAGCTGGCATTCAAGTGCAAGTTGTTAGC TTTGCTACAGAACATAATTGGGATTCTCTGGACTTTTATGATGGGGGAGACAACAATGCTCCAAGACTTGGAAGCTATTCAGGAACAACAATACCCCATC TTTTGAATAGTACGTCTAATAATCTGTATCTAAATTTTCAATCAGACATCAGTGTTTCTGCTGCAGGATTTCATCTTGAATACACAGCAATTGGTTTGGA TTCCTGTCCTGAACCACAAACTCCTAGCAGTGGAATTAAAATTGGAGACAGATATATGGTTGGAGATGTAGTATCCTTTCAGTGTGATCAAGGATATTCT CTTCAGGGTCACTCTCACATTACATGTATGCCAGGACCTGTAAGAAGATGGAATTATCCAATCCCAATTTGTTTAGCTCAGTGTGGTGGTGCTATGTCAG ACTTCAGTGGTGTGATCCTCAGTCCTGGGTTTCCTGGAAACTATCCCAGCAGTTTAGATTGCACATGGACAATAAATCTACCCATAGGTTTTGGTGTACA TCTCCAGTTTGTAAATTTTTCTACAGAAACCATACATGATTATTTGGAAGTACGAAGTGGATCCTCAGAAACTAGTACTGTTATTGGCCGGCTTAGTGGT CCTCAAATACCATCTTCCTTATTCAGCACCACCCATGAAACCAGCTTATATTTTCACAGTGACTATTCACAAAACAAACAAGGGTTTCATATTGTATACC AAGCCTATCAGTTGCAAAGCTGTCCTGATCCACGCCCGTTTCGAAATGGTTTTGTAATTGGTAATGATTTTACTGTGGGTCAAACCATTTCATTTGAATG TTTCCCAGGATACACATTAATTGGAAATTCAGCTCTCACATGCCTTCACGGAGTCAGTCGTAATTGGAATCATCCACTTCCAAGGTGTGAAGCTCTTTGT GGTGGGAATATAACTGCAATGAATGGCACCATTTATTCTCCTGGGTATCCTGATGAATATCCAAACTTTCAAGATTGTTTTTGGCTTGTAAGAGTACCCC CTGGGAATGGCATCTACATCAATTTTACTGTCCTTCAAACAGAACCAATATATGATTTCATTACTGTATGGGATGGACCAGACCAAAATTCACCTCAGAT CGGTCAGTTCAGTGGCAATACCGCTTTGGAATCAGTCTACAGTACTTCAAATCAGATTCTAATCAAATTCCACAGTGATTTCACAACAAGTGGCTTTTTT GTGCTCAGTTATCACGCCTATCAACTAAGGGTGTGCCAACCTCCACCACCTGTGCCCAATGCTGAAATTTTGACGGAAGATGATGAATTTGAAATAGGTG ATATTATTAGGTATCAGTGTCTTCCAGGATTTACTTTAGTTGGTAATGCAATTCTGACGTGCAGATTAGGAGAACGACTGCAGATGGATGGAGCACCTCC AGTTTGTCAAGTGCTCTGTCCTGCCAATGAATTACGGCTAGATTCTACTGGAGTCATATTGAGCCCTGGATATCCTGACAGTTACCCAAATCTTCAAATG TGTGCATGGAGCATTTCAGTGGAAAAGGGTTATAATATCACCATGTTTGTAGAATTCTTCCAGACAGAAAAGGAATTTGATGTTCTTCAGGTGTATGATG GACCAAATATTCAAAGTCCAGTGCTTATTTCCCTCAGTGGGGATTATTCATCTGCTTTTAATATAACAAGCAATGGTCATGAAGTATTTCTTCAGTGGTC AGCAGATCATGGCAATAACAAAAAAGGCTTCCGGATAAGATATATAGCTTTCTACTGTAGTACACCAGAATCCCCACCTCATGGATATATTATCAGTCAG ACAGGTGGGCAGCTTAACAGTGTGGTCCGTTGGGCCTGTGATCGAGGATTCCGACTTGTTGGAAAAAGCAGTGCTGTGTGCAGAAAGTCTTCCTATGGGT ATCATGCATGGGATGCGCCAGTCCCTGCCTGTCAAGCAATTTCCTGTGGGATTCCTAAAGCTCCAACAAATGGAGGAATACTAACAACAGACTATTTGGT AGGAACGCGAGTTACCTATTTTTGTAATGATGGATATCGATTGTCATCCAAAGAACTCACTACAGCTGTATGCCAATCAGATGGAACATGGAGCAATCAT AACAAGACCCCTCGCTGTGTTGTTGTTACATGTCCAAGCATCAATTCCTTTATCTTGGAACATGGAAGATGGCGAATTGTGAATGGCTCCCATTATGAAT ACAAAACCAAAGTAGTTTTCAGCTGTGACCCTGGTTATCATGGACTAGGTCCTGCCTCCATCGAATGTCTTCCTAATGGTACTTGGAGTTGGAGAAATGA AAGACCATATTGCCAAATTATTTCCTGTGGAGAACTACCTACACCTCCAAATGGAAATAAGATTGGAACTCAAACTTCATATGGCTCAACAGCTATCTTT ACCTGCGACTTGGGATTCATGCTTGTGGGCTCTGCTGTAAGGGAATGCCTTTCCTCAGGTCTTTGGAGTGAATCTGAAACCAGATGCCTAGCGGGTCATT GTGGAATTCCAGAACTGATTGTGAATGGTCAAGTCATTGGAGAAAATTATGGATATAGAGACACAGTTGTATATCAATGTAATCCTGGTTTTCGATTGAT TGGTTCTTCAGTGAGGATATGTCAACAGGATCACAATTGGTCTGGTCAGCTCCCATCCTGTGTGCCTGTTAGCTGTGGTCACCCTGGTAGTCCAATTTAT GGAAGAACAAGTGGAAATGGGTTCAACTTTAATGATGTGGTAACATTCTCATGCAATATTGGGTATCTTATGCAAGGGCCAACAAAGGCACAGTGCCAGG CCAACAGACAGTGGAGCCATCCTCCACCTATGTGCAAAGTGGTCAACTGTTCTGATCCTGGAATTCCAGCCAATTCTAAAAGAGAAAGTAAAATAGAACA TGGAAATTTTACTTACGGCACTGTGGTATTCTATGACTGCAATCCTGGATATTTTTTATTTGGATCTTCAGTTTTGATATGTCAACCAAATGGACAATGG GACAAACCTTTACCAGAATGTATCATGATTGACTGTGGACACCCTGGCGTTCCTCCTAATGCAGTCCTGTCTGGCGAGAAGTATACTTTTGGGTCTACTG TTCACTATTCCTGCACAGGAAAGCGTTCCCTTTTAGGCCAGTCATCAAGAACCTGCCAATTGAATGGCCATTGGAGTGGATCACAACCTCATTGTTCAGG TGATGCTACTGGGACATGTGGCGATCCAGGTACTCCCGGCCATGGCTCTAGACAGGAAAGCAATTTCAGAACTAAAAGTACTGTACGTTATGCTTGTGAT ACTGGTTACATCCTTCATGGCTCAGAAGAAAGAACATGTTTAGCTAATGGCAGTTGGACCGGAAGGCAGCCAGAGTGCAAAGCTGTGCAGTGTGGTAACC CAGGAACCACAGCCAATGGGAAAGTCTTCCGAATTGATGGCACAACATTTTCTAGTTCAGTCATTTATTCCTGCATGGAGGGATACATCCTTTCTGGACC TTCAGTTAGACAGTGCACAGCCAATGGAACATGGTCTGGAACTTTACCTAACTGTACAATAATCAGTTGTGGAGACCCAGGTATACCAGCCAATGGACTG AGATATGGAGATGATTATGTGGTTGGACAAAATGTTTCTTACATGTGCCAGCCAGGCTACACGATGGAATTGAATGGCTCCAGAATCAGGACTTGTACAA TTAATGGCACATGGAGTGGAGTAATGCCAACTTGTAGAGCTGTTACCTGCCCAACTCCTCCCCAGATCTCTAATGGAAGGCTGGAAGGAACAAATTTCGA CTGGGGCTTTAGTATTAGCTACATCTGTTCTCCAGGCTATGAGCTATCCTTCCCTGCTGTTTTGACCTGTGTAGGGAATGGTACCTGGAGTGGTGAAGTA CCGCAGTGCTTACCAAAGTTTTGTGGTGACCCTGGTATACCTGCCCAAGGAAAAAGAGAAGGCAAAAGCTTTATATACCAGTCAGAGGTTTCATTCAGCT GCAATTTTCCTTTCATATTAGTGGGATCAAGCACCAGAATATGTCAAGCAGATGGCACTTGGAGTGGTTCATCACCTCACTGCATAGAGCCTACCCAAAC CTCTTGTGAAAACCCAGGTGTGCCTCGGCATGGATCTCAGAACAATACATTCGGATTTCAAGTAGGAAGTGTTGTACAGTTCCATTGCAAAAAAGGACAC CTTCTCCAAGGGTCTACAACACGCACCTGCCTCCCTGATCTTACGTGGAGTGGGATTCAGCCTGAATGCATACCCCACAGCTGTAAACAGCCAGAAACTC CTGCTCATGCAAATGTCGTAGGGATGGACCTTCCATCTCATGGGTATACACTGATTTATACCTGTCAGCCTGGCTTCTTCTTAGCAGGTGGAACAGAACA TAGAGTGTGTAGATCCGATAACACCTGGACTGGAAAAGTTCCCATTTGTGAAGCTGGTTCTAAAATATTGGTGAAAGATCCTAGACCTGCACTGGGAACA CCCAGCCCAAAGCTAAGTGTTCCTGATGATGTATTTGCCCAAAATTATATATGGAAAGGCTCTTACAATTTCAAAGGAAGGAAACAACCCATGACCTTAA CAGTTACTAGTTTCAATGCTTCCACTGGGAGAGTTAACGCAACACTGAGCAATAGCAACATGGAGCTGCTACTTTCAGGGGTATATAAAAGCCAGGAAGC TCGCCTAATGTTACGCATATATCTTATTAAAGTACCTGCTCATGCTTCTGTGAAGAAAATGAAGGAAGAAAATTGGGCAATGGATGGCTTTGTTTCTGCT GAGCCTGATGGAGCTACTTATGTATTTCAAGGATTTATTCAAGGCAAAGATTATGGACAATTTGGCCTACAAAGACTGGGACTGAATATGTCAGAAGGTT CAAATTCTTCAAATCAACCTCATGGTACAAATAGTAGTTCTGTAGCCATTGCTATTCTTGTGCCTTTTTTTGCACTTATATTTGCAGGATTTGGATTTTA TCTTTATAAACAAAGGACTGCACCTAAAACACAGTATACAGGATGTTCAGTTCATGAAAATAACAATGGCCAAGCAGCTTTTGAAAATCCCATGTATGAC ACCAACGCAAAGTCAGTGGAAGGGAAGGCGGTACGATTTGATCCCAACTTGAACACGGTTTGCACAATGGTATAACGAGGCAACCTTTGCCTTCTTCAGA AGCTTGGAAATCGACACACAAAACAGTGCACATTTAGTTCACTGCTAAACAAATTAAAGCACACTTTTCAGGACTTGCTGGGTCACCTTTTCCTGAGGAA TGATACAGAAGAGTGTTTTTTCATAAACTGGACCATAATTCTTCATGTTTACCATGGAGAGTTTTACAGAAATTTGGCTGCACTCTGAGAGTGCTTACTC ACAGTTTATTTGCTTTTTTTAAAAAGGAGATTATTCTAAAATATAAACTTATTTGCATATATTGGAGGAGCATCCACTATCAGTATTTCTGTGCTTTATA AACTATATTAGAGGGACTGGGTTTAAAAAAAAAGATATAGGGTAGAAATAAGAGCTATACTTACAAGAGTCAATAGATCACTGACTTCTCTTTAACTGTC CTGAGCTACATCACGCCCACAAATCTGTCTTTCATACCACTCTATCTGCCATTCATTCTTGTTAAATGAGGCATTGTTTTCTTTATTTAAGATTGAGTTA TGACTTTAAATGTTTATGAGCTAGTTTATGCCTCGGAAGACATAAGGTTTCCCATTCCAATTTGAATCTTTCTATTTCTTTAGCATCATATTGCTCTTCT TCTTTTAGACTGGTTGTCATAGTTTCTGCAAAGGGCAAGTTCATTGTGCTACCCTCCCAATTCCCCCATTATGGAGTAACCAGTATTATTCAGTGAGCTA TGGGGTAGTGTTTCACTCCTTGCTTCAATATGGTTTTTTCCTATTTATTTTTATTATTTTTTAATCCCAAATGTGATAGTAGCTTCAGTATGTTTCCTCA CCCAAAAACCATTTGGCTGGCAGAAATTATCTAGAAAAATTATTATTTTGCAGTTATCTGAGACACCAAACTTACCATCCTTTATTTTACAATATTTTTG ATCGACCAAATAAAATGTCCTAATAATCTACTCTATTTATATCTACATTTCCTTCCAGCTGAGTCTTCAAATTTAGCATTATTTTGACACTTTTAATTTT CATTTAACAATGGATTAGAAAAATATTTTGGTCTAGCCACTAAACATAATGACTGAAAAAAATTATTATTATAAATCACCAATATAAATTTATTGCCTAC AATTGTGGACTTATCATATTTTTATATATTTTTAAATTTCTGTACCTTTATTGTTAAACACCAAGTTTCACATACAAGAGGTTTCTTTCATTGTCAAATT AAGATATGTATTTGTAAGTTATTGGTGGCTCATTTAAACTGTATCATACAGTAATGCCAGCATTTTTATTTAATAGGTCATCGTCTTCCTTTTATAGCTG TTTTACTTCATTGAATACGATCATGTACCCAGTGTTAACTCTTTGTTGTTGTCCCTTTCAAATATGGATAACTCTGTGAACAGTCTTGACTTTTTGTATC ATGAGACAGAGTGCCTAAGAGAAACCCTTGCACCTGGGAGCGCTGCTTGGCTCTATCTCTACAACATTTAATGAATTTCTTGTAAACCACTTTGAGATAC ATTGTTTTGGAAATTCATACAATTTTCTCAACATGGTACTCTACTGGCAGGATGCAGTTTTAAATTTTATGCCATCAGTTATTTATTCTTGTTTATTCAA ATGACTGCAATAACAATGATTCATTCATTAATGTTAAGGCTAATACATTTAAGATCTTGTTTAAACAATGTTTCTTCTGCAACTGGCTACTCCTCTTATA TTAATGCATACACTTTTGTAAAGAAGTATATTTTTATGAAAAGAAACTTTGTAAAAGTATGATGTAAATTTTCAGTGCAATGTAAACAAAATAAAAATGG ATAATTGCTTTTGTAAAA

refseq_CSMD3.F2 (forward primer)
refseq_CSMD3.R2 (reverse primer)
Single exon skipping

Frame 0

YTPRPFGGPESRTTPQPLGESSASWRKEASSSR SSGKGAEVAGCCDS*TTSSAQPG*MWSWFLCWKP VQLDRQTASGFIYTCGGTLKGLNGTIESPGFPY GYPNGANCTWVIIAEERNRIQIVFQSFALEEEY DYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSV FSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGV PPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQL TCIANSVNTASWDFPVPICRAEDACGGTMRGSSG IISSPSFPNEYHNNADCTWTIVAEPGDTISLIF TDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPI ISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTH TTSTGELEEHNRTTTGAIAVASTPADVTVSSVT AVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLS PHPADTQSTRRRPRHAEQIERTKELAVVTHRVKK AIDFKSRGFKLFPGKDNSNKFSILNEGGIKTAS NLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDY VLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGS NLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNT NKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRT VLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSV GFKVNYKEIEKESCGDPGTPLYGIREGDGFSNR DVLRFECQFGFELIGEKSIVCQENNQWSANIPI CIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWT IISDPGSRIHLSFNDFDLESQFDFLAVKDGDSP ESPILGTFTGAEVPSHLTSNSHILRLEFQADHS MSGRGFNITYNTFGHNECPDPGIPINARRFGDNF QLGSSISVICEEGFIKTQGTETITCILMDGKVM WSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYK DSLNCEWVIEAEPGHSIKITFERFQTELNYDVLE VHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYL LFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIP VHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLC EKNHWWSHPLPTCDALCGGDVRGPSGTILSPGY PEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED HHDYLLITENGSFTQPLARLTGSDLPPTINAGLY GNFRAQLRFISDFSISYEGFNITFSEYNLEPCE DPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEG TSEIICLGGGRRVWSAPLPRCVAECGASATNNEG ILLSPNYPLNYENNHECIYSIQVQAGKGINISA RTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMR GLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFE LSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNP GYTLHGSSLLKCMTGERRAWDYPLPSCIAECGG RFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPG NIVSLQFLAFDTEASHDILRVWDGPPENDMLLK EISGSLIPEGIHSTLNIVTIQFDTDFYISKSGF AIQFSSSVATACRDPGVPMNGTRNGDGREPGDTV VFQCDPGYELQGEERITCIQVENRYFWQPSPPV CIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDW TITVNADYVISLAFISFSIEPNYDFLYIYDGPDS NSPLIGSFQDSKLPERIESSSNTMHLAFRSDGS VSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMD YKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPG WNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYS VGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVE VYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITI RFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPE PRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAI RCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTI LSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVS FATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPH LLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLD SCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYS LQGHSHITCMPGPVRRWNYPIPICLAQCGGAMS DFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVH LQFVNFSTETIHDYLEVRSGSSETSTVIGRLSG PQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVY QAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFEC FPGYTLIGNSALTCLHGVSRNWNHPLPRCEALC GGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVP PGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQI GQFSGNTALESVYSTSNQILIKFHSDFTTSGFF VLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIG DIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPP VCQVLCPANELRLDSTGVILSPGYPDSYPNLQM CAWSISVEKGYNITMFVEFFQTEKEFDVLQVYD GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWS ADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQ TGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYG YHAWDAPVPACQAISCGIPKAPTNGGILTTDYLV GTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNH NKTPRCVVVTCPSINSFILEHGRWRIVNGSHYE YKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNE RPYCQIISCGELPTPPNGNKIGTQTSYGSTAIF TCDLGFMLVGSAVRECLSSGLWSESETRCLAGH CGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLI GSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIY GRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQ ANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEH GNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQW DKPLPECIMIDCGHPGVPPNAVLSGEKYTFGST VHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSG DATGTCGDPGTPGHGSRQESNFRTKSTVRYACD TGYILHGSEERTCLANGSWTGRQPECKAVQCGN PGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGP SVRQCTANGTWSGTLPNCTIISCGDPGIPANGL RYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCT INGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFD WGFSISYICSPGYELSFPAVLTCVGNGTWSGEV PQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFS CNFPFILVGSSTRICQADGTWSGSSPHCIEPTQT SCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGH LLQGSTTRTCLPDLTWSGIQPECIPHSCKQPET PAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEH RVCRSDNTWTGKVPICEAGSKILVKDPRPALGT PSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTL TVTSFNASTGRVNATLSNSNMELLLSGVYKSQEA RLMLRIYLIKVPAHASVKKMKEENWAMDGFVSA EPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEG SNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFY LYKQRTAPKTQYTGCSVHENNNGQAAFENPMYD TNAKSVEGKAVRFDPNLNTVCTMV*RGNLCLLQ KLGNRHTKQCTFSSLLNKLKHTFQDLLGHLFLRN DTEECFFINWTIILHVYHGEFYRNLAAL*ECLL TVYLLFLKRRLF*NINLFAYIGGASTISISVLY KLY*RDWV*KKRYRVEIRAILTRVNRSLTSL*LS *ATSRPQICLSYHSICHSFLLNEALFSLFKIEL *L*MFMS*FMPRKT*GFPFQFESFYFFSIILLF FF*TGCHSFCKGQVHCATLPIPPLWSNQYYSVSY GVVFHSLLQYGFFLFIFIIF*SQM***LQYVSS PKNHLAGRNYLEKLLFCSYLRHQTYHPLFYNIF DRPNKMS**STLFISTFPSS*VFKFSIILTLLIF I*QWIRKIFWSSH*T**LKKIIIINHQYKFIAY NCGLIIFLYIFKFLYLYC*TPSFTYKRFLSLSN *DMYL*VIGGSFKLYHTVMPAFLFNRSSSSFYSC FTSLNTIMYPVLTLCCCPFQIWITL*TVLTFCI MRQSA*EKPLHLGALLGSISTTFNEFLVNHFEI HCFGNSYNFLNMVLYWQDAVLNFMPSVIYSCLFK *LQ*Q*FIH*C*G*YI*DLV*TMFLLQLATPLI LMHTLL*RSIFL*KETL*KYDVNFQCNVNKIKM DNCFCK

Frame 1

TPLGPLEDRRAGRRRSPWGSPAPAGEKKLHLPD HPGKGQRWPVVATHKQPLQHNPVECGVGSFAGN LYSLTDRQPQDLFIHVVEL*KDLMAL*KALVFHM DIQMVQTAHG***QKNEIEYKLFFSHLL*KKNT TTYHYMMDILILQTLGQG*QDSICHLQ*QVPNL CSHYV*PVILQLVLMDLRYITKNCRVALVEILVF HPKVYYMAQDSTSGTRSATAV*LDTSLMATLSS PA*PIQLIQLRGIFLFLSVELKMLVEEQ*EDPV ASYPALVFLMSTITMLIALGPL*QSLGTQFHSYL LIFKWKRNMIT*K*KVLSHLPYGYLE*IYHHQL SATKTGSDCILLQTAIIDTVDLVLPIKVLLH*P TLPPLVS*RSITGLPLVLLLLLAHLQMLLYPVLQ LSPSIDFPRNSECKLRVSEIQVWTPTRPRTGSL LIQQIHKVPGEDQDMLNR*KELKSLQLLLIE*K RP*ILNLEDLNCFQGKTTATSFLS*MREVLKQLP IYAQIQENQKMGRESDQILALDQLCSSLVMKIM SYRAQRASPVNG*LKFLLLGVITGLCVK*KRVA LIFKDQVVPLHLPTFRSSMTAMHNVSGSSQQ*IQ IRLSR*ILKNLIWRLAMIP*QLAMGAKLEILGQ CSKC*LEALYQT***A*VAKCGCTFKRTKVLDL LVSRLTTKKLRKKVVVILVHPYMELEKAMDFLIV MF*GLNASLGLN*LERNPLFVKRITNGLQTYPS VSFPACLTLLHQWEQFFLLITQKGMEII*IASG R*SLIQGAGYIFLSMTLTWNPSLISLLLKMVTLQ NPQFLEPLLGLRCLPILLVIVTYCDWNFRLTTQ CQDVALTSLTTHLDIMNALILEYQSMHGGLGTT FN*EVQFQLFVKKDLLKPREQKQLHVFLWMEK*C GVD*FQNVEPHVVAIFQLPVE*FSHQDGQDTTK TL*IVSG*LKLNLDTLSKLHLKDFRLN*IMMFW KFMMGQIFCHPCLDLTMAPKCPSFYLVAVILYTF YLQQTTVVPIMVSRFIMKVLQ*TRILVWTLAYL YMAVAMVMISPLALLFHLVVIQDTG*VMKSPFY AKKTTGGVIHFQPVMHYVEEMLEGLVEQSYHLVT RNFIQIL*IVHGLLM*PMEKVCSSTSTLFIWKT IMTTY*SQRMAVLPNHWHA*LVQIFLQQSMLVS MEISGLNCVSFQIFQYHMKDLT*HSLNITLNLVK ILAFLNMVVESGSTLGLVTL*PSHALRVIDWKE HQRSSVLVVADECGVHLCQGVWLNVVHLQRIMK EFCCLQIIHSTMKTTMNAFIVFRFKQERESIFQP EHFI*HKEMFLRFMMEKIKRLIY*VLLLVHLCA D*HLVVLQINSG*NLIPILKGQMKAFNLCIPVL NSHTVKILAFHNLDTRSVTKATLLVAPSFMDAIQ ATLSTEVAFSSA*QGREGHGTILCLPVLLNVEV VLKENHQEESYLLAILFHMTITCVACG*LR*IL EILSACSFLLLIRKHHMIYSESGTVHQKMICF*R KLVDLLFLKEFIAPSI**PSSLTRIFILANLDL QFSFQVLLPLRVVTQGSP*MGLEMGMEENLGTL LFFNVTQDMNFKERKE*PAFR*KIGTSGSPAHQS V*HPVEAI*QDLQALFFHQTSLIHIRIAETVTG LSPSMQTMLSPWRSSVLA*NQTMTSSISMMDQT VIAH*LEVFKTASYQRE*KAAQIQCIWLFGVMDL LVTLDFI*NTKQNCESPALIQAI**MAPDLEWI IN*GQQSPITVMLVMFFKVIQHSPVSWEMMEDL DGIEPCQVVMRPVEVVQQVQKALFYHQTIQKITV WDIIVFIL*QFQRSLWCLASLYFSRHHSTMLLR CMMGQLSNLLCYLPSQDPIQENHFH*VQVIRSQ FDLLQLDQ*QLRDFTLFTKLFLEQVLHNAVLCLN QDSEEELAMNLQSVHRFFLIVIQDIFSMDP*QL GVKQCPILWPSGMIPYLLVLCPVVEF*LSAKGL FCHLDTLSLMTTI*IVCGRSQCQRELAFKCKLLA LLQNIIGILWTFMMGETTMLQDLEAIQEQQYPI F*IVRLIICI*IFNQTSVFLLQDFILNTQQLVW IPVLNHKLLAVELKLETDIWLEM*YPFSVIKDIL FRVTLTLHVCQDL*EDGIIQSQFV*LSVVVLCQ TSVV*SSVLGFLETIPAV*IAHGQ*IYP*VLVY ISSL*IFLQKPYMIIWKYEVDPQKLVLLLAGLVV LKYHLPYSAPPMKPAYIFTVTIHKTNKGFILYT KPISCKAVLIHARFEMVL*LVMILLWVKPFHLN VSQDTH*LEIQLSHAFTESVVIGIIHFQGVKLFV VGI*LQ*MAPFILLGILMNIQTFKIVFGL*EYP LGMASTSILLSFKQNQYMISLLYGMDQTKIHLR SVSSVAIPLWNQSTVLQIRF*SNSTVISQQVAFL CSVITPIN*GCANLHHLCPMLKF*RKMMNLK*V ILLGISVFQDLL*LVMQF*RAD*ENDCRWMEHL QFVKCSVLPMNYG*ILLESY*ALDILTVTQIFKC VHGAFQWKRVIISPCL*NSSRQKRNLMFFRCMM DQIFKVQCLFPSVGIIHLLLI*QAMVMKYFFSG QQIMAITKKASG*DI*LSTVVHQNPHLMDILSVR QVGSLTVWSVGPVIEDSDLLEKAVLCAESLPMG IMHGMRQSLPVKQFPVGFLKLQQMEEY*QQTIW *ERELPIFVMMDIDCHPKNSLQLYANQMEHGAII TRPLAVLLLHVQASIPLSWNMEDGEL*MAPIMN TKPK*FSAVTLVIMD*VLPPSNVFLMVLGVGEM KDHIAKLFPVENYLHLQMEIRLELKLHMAQQLSL PATWDSCLWALL*GNAFPQVFGVNLKPDA*RVI VEFQN*L*MVKSLEKIMDIETQLYINVILVFD* LVLQ*GYVNRITIGLVSSHPVCLLAVVTLVVQFM EEQVEMGSTLMMW*HSHAILGILCKGQQRHSAR PTDSGAILHLCAKWSTVLILEFQPILKEKVK*N MEILLTALWYSMTAILDIFYLDLQF*YVNQMDNG TNLYQNVS*LTVDTLAFLLMQSCLARSILLGLL FTIPAQESVPF*ASHQEPAN*MAIGVDHNLIVQ VMLLGHVAIQVLPAMALDRKAISELKVLYVMLVI LVTSFMAQKKEHV*LMAVGPEGSQSAKLCSVVT QEPQPMGKSSELMAQHFLVQSFIPAWRDTSFLD LQLDSAQPMEHGLELYLTVQ*SVVETQVYQPMD* DMEMIMWLDKMFLTCASQATRWN*MAPESGLVQ LMAHGVE*CQLVELLPAQLLPRSLMEGWKEQIS TGALVLATSVLQAMSYPSLLF*PV*GMVPGVVKY RSAYQSFVVTLVYLPKEKEKAKALYTSQRFHSA AIFLSY*WDQAPEYVKQMALGVVHHLTA*SLPK PLVKTQVCLGMDLRTIHSDFK*EVLYSSIAKKDT FSKGLQHAPASLILRGVGFSLNAYPTAVNSQKL LLMQMS*GWTFHLMGIH*FIPVSLASS*QVEQN IECVDPITPGLEKFPFVKLVLKYW*KILDLHWEH PAQS*VFLMMYLPKIIYGKALTISKEGNNP*P* QLLVSMLPLGELTQH*AIATWSCYFQGYIKARK LA*CYAYILLKYLLMLL*RK*RKKIGQWMALFLL SLMELLMYFKDLFKAKIMDNLAYKDWD*ICQKV QILQINLMVQIVVL*PLLFLCLFLHLYLQDLDF IFINKGLHLKHSIQDVQFMKITMAKQLLKIPCMT PTQSQWKGRRYDLIPT*TRFAQWYNEATFAFFR SLEIDTQNSAHLVHC*TN*STLFRTCWVTFS*G MIQKSVFS*TGP*FFMFTMESFTEIWLHSESAYS QFICFF*KGDYSKI*TYLHILEEHPLSVFLCFI NYIRGTGFKKKDIG*K*ELYLQESIDH*LLFNC PELHHAHKSVFHTTLSAIHSC*MRHCFLYLRLSY DFKCL*ASLCLGRHKVSHSNLNLSISLASYCSS SFRLVVIVSAKGKFIVLPSQFPHYGVTSIIQ*A MG*CFTPCFNMVFSYLFLLFFNPKCDSSFSMFPH PKTIWLAEII*KNYYFAVI*DTKLTILYFTIFL IDQIKCPNNLLYLYLHFLPAESSNLALF*HF*F SFNNGLEKYFGLATKHND*KKLLL*ITNINLLPT IVDLSYFYIFLNFCTFIVKHQVSHTRGFFHCQI KICICKLLVAHLNCIIQ*CQHFYLIGHRLPFIA VLLH*IRSCTQC*LFVVVPFKYG*LCEQS*LFVS *DRVPKRNPCTWERCLALSLQHLMNFL*TTLRY IVLEIHTIFSTWYSTGRMQF*ILCHQLFILVYS NDCNNNDSFINVKANTFKILFKQCFFCNWLLLLY *CIHFCKEVYFYEKKLCKSMM*IFSAM*TK*KW IIAFVK

Frame 2

HPSALWRTGEPDDAAALGGVQRQLAKRSFIFQI IRERGRGGRLLRLINNLFSTTRLNVELVPLLET CTA*PTDSLRIYLYMWWNFKRT*WHYRKPWFSI WISKWCKLHMGNNSRRTK*NTNCFSVICSRRRIR LLIII*WTSSSYKL*DKVNRIPSATSSDKYQIC VLTTFDQ*FCS*CSWI*GILRRIAE*LLWKSWC STQRCIIWHKIRRRGQDPLQLCNWIHP*WPPSAH LHSQFS*YSFVGFSCSYL*S*RCLWRNNERIQW HHIQP*FS**VP*QC*LHLDHCSRAWGHNFTHI Y*FSNGREI*LLRNRRF*ATYHMVIWNEYTTTNY QQQKLAQTAFCYRQQSSIPWI*CSLSRFFYIDP HYLHW*VRGA*QDYHWCYCCC*HTCRCYCIQCY SCHHP*TFRGTASASYESQKFRSGPQHVQGRALS SSSRYTKYQEKTKTC*TDRKN*RACSCYS*SEK GHRF*I*RI*IVSRERQQQQVFYLK*GRY*NSF QFMPRSRRTRKWEENRIRF*PWINCAVLL**RLC PTGRKEHHLSTDS*SFCCLE*SQACV*SENVWL *SSRTKWYLYISQLSVPV*QQCTMCLGHHSSEY K*GYPDKF*RI*SGDWL*YLDNWRWGRSWRS*DS APSADWKLCTRLDSEHE*PNVAAPSNGRKCWIC WFQG*LQRN*ERKLW*SWYTLIWN*RRRWIF*S *CFKV*MPVWV*INWREIHCLSRE*PMVCKHTHL YLSLPV*LYCTNGNSSFS*LPRRVWK*FKLHLD DNL*SREPDTSFFQ*L*PGIPV*FPCC*RW*LS RIPNSWNLYWG*GAFPSY***SHTAIGISG*PLN VRTWL*HHLQHIWT**MP*SWNTNQCTAVWGQL SIRKFNFSYL*RRIY*NPGNRNNYMYSYGWKSN VEWTDSKMWSPMWWPFFSSQWSDSLTRMARILQR LFEL*VGD*S*TWTLYQNYI*KISD*TEL*CSG SS*WAKSSVTLAWILQWHPSAPVSI**Q*FYIP SIYNRQQSFQ*WFQDSL*KCYSEHVFLFGPWHTC TWPSLWS*FLHWLYCFI*L*FRIQVES*RAPSM RKKPLVESSTSNL*CIMWRRC*RA*WNNLITWL PGILSKFSELYMDC*CNPWKRCAVQLPHFSFGRP S*LLTDHREWQFYPTTGTPDWFRSSSNNQCWSL WKFQGSIAFHFRFFNII*RI*HNIL*I*P*TL* RSWHSSIW*SNRVQLWDW*HSDLLMLFGLSTGRN IRDHLSWWWPTSVECTSAKVCG*MWCICNE**R NFAVSKLSTQL*KQP*MHL*YSGSSRKGNQYFS QNISFSTRRCS*DL*WKR*NDSSTRCFYWCIYAR TDT**YFKSTLARI*FRY*RDR*RLSTCVYQF* TLTL*RSWHSTIWIQDQ*PRPLCW*HHHLWMQS RLHSPRK*PSQVHDRGEKGMGLSSAFLYC*MWRS F*RRIIRKNLISWLSFSI*Q*PALHVDD*GRSW KYCQLAVSCF*YGSIT*YTPSLGRSTRK*YAFK GN*WISYS*RNS*HPQYSNHPV*HGFLY*QIWIC NSVFKFCCHCVS*PRGPHEWDSKWGWKRTWGHC CFSM*PRI*TSRRGKNNLHSGRKSVLLAAQPTS LYSTLWRQFNRIFRLYSFTKLPSSISA*QRL*LD YHRQCRLCYLLGVHQF*HRTKL*LPLYL*WTRQ **PTDWKFSRQQVTRENRKQLKYNAFGFSE*WI C*LHWISSRIQSKTARVLL*SRQYNEWHQTWNGL *IRVNSHLLL*CWLCSSRLFNTHLYHGR*WKTW ME*SLAKLSCALWKSFNRFRRHCSITKLSKKLQ CGT*LCLFYSSSKGVCGVWPVCIFPDITPRCC*G V*WANSAIFSVIFPLRIPFRRITSTEFR*SDHN SIYFSWTNNS*GISLCLPSCS*NKFYTMQFCA* TKIRKKNWQ*ICSRFIGSF*L*SRIYSPWIHSN* V*NSAQFFGPVE*FLTYLYCALWWNFN*AQRDY FVTWIP*AL*QQSELCVEDHSARGSWHSSASC* LCYRT*LGFSGLL*WGRQQCSKTWKLFRNNNTPS FE*YV**SVSKFSIRHQCFCCRISS*IHSNWFG FLS*TTNS*QWN*NWRQIYGWRCSILSV*SRIF SSGSLSHYMYARTCKKMELSNPNLFSSVWWCYVR LQWCDPQSWVSWKLSQQFRLHMDNKSTHRFWCT SPVCKFFYRNHT*LFGSTKWILRN*YCYWPA*W SSNTIFLIQHHP*NQLIFSQ*LFTKQTRVSYCIP SLSVAKLS*STPVSKWFCNW**FYCGSNHFI*M FPRIHINWKFSSHMPSRSQS*LESSTSKV*SSL WWEYNCNEWHHLFSWVS**ISKLSRLFLACKSTP WEWHLHQFYCPSNRTNI*FHYCMGWTRPKFTSD RSVQWQYRFGISLQYFKSDSNQIPQ*FHNKWLF CAQLSRLSTKGVPTSTTCAQC*NFDGR**I*NR* YY*VSVSSRIYFSW*CNSDVQIRRTTADGWSTS SLSSALSCQ*ITARFYWSHIEPWIS*QLPKSSN VCMEHFSGKGL*YHHVCRILPDRKGI*CSSGV*W TKYSKSSAYFPQWGLFICF*YNKQWS*SISSVV SRSWQ*QKRLPDKIYSFLL*YTRIPTSWIYYQS DRWAA*QCGPLGL*SRIPTCWKKQCCVQKVFLWV SCMGCASPCLSSNFLWDS*SSNKWRNTNNRLFG RNASYLFL**WISIVIQRTHYSCMPIRWNMEQS *QDPSLCCCYMSKHQFLYLGTWKMANCEWLPL*I QNQSSFQL*PWLSWTRSCLHRMSS*WYLELEK* KTILPNYFLWRTTYTSKWK*DWNSNFIWLNSYL YLRLGIHACGLCCKGMPFLRSLE*I*NQMPSGSL WNSRTDCEWSSHWRKLWI*RHSCISM*SWFSID WFFSEDMSTGSQLVWSAPILCAC*LWSPW*SNL WKNKWKWVQL**CGNILMQYWVSYARANKGTVPG QQTVEPSSTYVQSGQLF*SWNSSQF*KRK*NRT WKFYLRHCGIL*LQSWIFFIWIFSFDMSTKWTM GQTFTRMYHD*LWTPWRSS*CSPVWREVYFWVYC SLFLHRKAFPFRPVIKNLPIEWPLEWITTSLFR *CYWDMWRSRYSRPWL*TGKQFQN*KYCTLCL* YWLHPSWLRRKNMFS*WQLDRKAARVQSCAVW*P RNHSQWESLPN*WHNIF*FSHLFLHGGIHPFWT FS*TVHSQWNMVWNFT*LYNNQLWRPRYTSQWT EIWR*LCGWTKCFLHVPARLHDGIEWLQNQDLYN *WHMEWSNANL*SCYLPNSSPDL*WKAGRNKFR LGL*Y*LHLFSRL*AILPCCFDLCREWYLEW*S TAVLTKVLW*PWYTCPRKKRRQKLYIPVRGFIQL QFSFHISGIKHQNMSSRWHLEWFITSLHRAYPN LL*KPRCASAWISEQYIRISSRKCCTVPLQKRT PSPRVYNTHLPP*SYVEWDSA*MHTPQL*TARNS CSCKCRRDGPSISWVYTDLYLSAWLLLSRWNRT *SV*IR*HLDWKSSHL*SWF*NIGERS*TCTGN TQPKAKCS**CICPKLYMERLLQFQRKETTHDLN SY*FQCFHWES*RNTEQ*QHGAATFRGI*KPGS SPNVTHISY*STCSCFCEENEGRKLGNGWLCFC *A*WSYLCISRIYSRQRLWTIWPTKTGTEYVRRF KFFKSTSWYK**FCSHCYSCAFFCTYICRIWIL SL*TKDCT*NTVYRMFSS*K*QWPSSF*KSHV* HQRKVSGREGGTI*SQLEHGLHNGITRQPLPSSE AWKSTHKTVHI*FTAKQIKAHFSGLAGSPFPEE *YRRVFFHKLDHNSSCLPWRVLQKFGCTLRVLT HSLFAFFKKEIILKYKLICIYWRSIHYQYFCAL* TILEGLGLKKKI*GRNKSYTYKSQ*ITDFSLTV LSYITPTNLSFIPLYLPFILVK*GIVFFI*D*V MTLNVYELVYASEDIRFPIPI*IFLFL*HHIALL LLDWLS*FLQRASSLCYPPNSPIME*PVLFSEL WGSVSLLASIWFFPIYFYYFLIPNVIVASVCFL TQKPFGWQKLSRKIIILQLSETPNLPSFILQYF* STK*NVLIIYSIYIYISFQLSLQI*HYFDTFNF HLTMD*KNILV*PLNIMTEKNYYYKSPI*IYCL QLWTYHIFIYF*ISVPLLLNTKFHIQEVSFIVKL RYVFVSYWWLI*TVSYSNASIFI**VIVFLL*L FYFIEYDHVPSVNSLLLSLSNMDNSVNSLDFLY HETECLRETLAPGSAAWLYLYNI**ISCKPL*DT LFWKFIQFSQHGTLLAGCSFKFYAISYLFLFIQ MTAITMIHSLMLRLIHLRSCLNNVSSATGYSSY INAYTFVKKYIFMKRNFVKV*CKFSVQCKQNKNG *LLL*