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Sequences

Sequence NM_004936

GGCTCCCCACTCTGCCAGAGCGAGGCGGGGCAGTGAGGACTCCGCGACGCGTCCGCACCCTGCGGCCAGAGCGGCTTTGAGCTCGGCTGCGTCCGCGCTA GGCGCTTTTTCCCAGAAGCAATCCAGGCGCGCCCGCTGGTTCTTGAGCGCCAGGAAAAGCCCGGAGCTAACGACCGGCCGCTCGGCCACTGCACGGGGCC CCAAGCCGCAGAAGGACGACGGGAGGGTAATGAAGCTGAGCCCAGGTCTCCTAGGAAGGAGAGAGTGCGCCGGAGCAGCGTGGGAAAGAAGGGAAGAGTG TCGTTAAGTTTACGGCCAACGGTGGATTATCCGGGCCGCTGCGCGTCTGGGGGCTGCGGAATGCGCGAGGAGAACAAGGGCATGCCCAGTGGGGGCGGCA GCGATGAGGGTCTGGCCAGCGCCGCGGCGCGGGGACTAGTGGAGAAGGTGCGACAGCTCCTGGAAGCCGGCGCGGATCCCAACGGAGTCAACCGTTTCGG GAGGCGCGCGATCCAGGTCATGATGATGGGCAGCGCCCGCGTGGCGGAGCTGCTGCTGCTCCACGGCGCGGAGCCCAACTGCGCAGACCCTGCCACTCTC ACCCGACCGGTGCATGATGCTGCCCGGGAGGGCTTCCTGGACACGCTGGTGGTGCTGCACCGGGCCGGGGCGCGGCTGGACGTGCGCGATGCCTGGGGTC GTCTGCCCGTGGACTTGGCCGAGGAGCGGGGCCACCGCGACGTTGCAGGGTACCTGCGCACAGCCACGGGGGACTGACGCCAGGTTCCCCAGCCGCCCAC AACGACTTTATTTTCTTACCCAATTTCCCACCCCCACCCACCTAATTCGATGAAGGCTGCCAACGGGGAGCGGCGGAAAGCCTGTAAGCCTGCAAGCCTG TCTGAGACTCACAGGAAGGAGGAGCCGACCGGGAATAACCTTCCATACATTTTTTTCTTTGTCTTATCTGGCCCTCGACACTCACCATGAAGCGAAACAC AGAGAAGCGGATTTCCAGGGATATTTAGGAGTGTGTGACATTCCAGGGGTCGTTTGCTTTTCAGGGTTTTCTGAGGGAAAGTGCATATGAAATCCTTGAC TGGACCTGGTGGCTACGAATCTTCCGATGGATGAATCTCCCACTCCAGCGCTGAGTGGGAGAAGGCAGTGATTAGCACTTGGGTGACGGCAGTCGATGCG TTCACTCCAATGTCTGCTGAGGAGTTATGGTGAACCCACAACTTAGGCCCTAGCGGCAGAAAGGAAAACCTGAAGACTGAGGACAAAGTGGAGGAGGGCC GAGGTGGGCTTCAGTAAGTCCCCGGCGGCGCTTTAGTTTGAGCGCATGGCAAGTCACATGCGTAAACGACACTCTCTGGAAGCCCTGGAGACCCTCGCCC AACTCCACCAGATAGCAGAGGGGTAAGAGAGGATGTGCAAGCGACGACAGATGCTAAAATCCCTGGATCACGACGCTGCAGAGCACCTTTGCACAGGATG CTGGCCTTTGCTCTTACTACACTGAGGAGAGATTCCCGCGGGTTCCGCAGGCAGACTACACAGGATGAGGTGGTGGAGTGGAGTGAGAGCAATTGTAACG GTTAACTGTAACGTTTTCTTTCACACACACACACACACACACACACACACATGCTAGGATGCGGAAATCCCCTTATGACTTGCTACTTTTTGATTTTGTG ATATTTTGTACTTTTTAGTTGTTCAGCAACTGTCTTATTTAATGGGGAGATTTTAAGTAACATAACTAGTGGCTCTCAGTTAAAATGTGAGGAAGAACTA CAGCTCTTAAATGTAGCAATGGCACTGTTGCAAACTCAGTGCAAACGCCTAGATTGCTTTCTTCTTAACCTATTTATTTCTTTGTTAAATTTTTCTGATT GTTTCCTTTATAGAGTGTCTCAGGGTGCAGAGGTCAGACTAAGAAATATTCCAAATGTCTTTTAGAAGATAGATGCACTTATGCAGTAAATTATCTTGGG ATAGTTCCCAAAAGATTGCTGAAAAAGTAGATTGAGTATAAAAACTTGAAAATATATGATGGCTCGTGGGATGTCCTACTATCACTGAACAAACTAAAGG TGCACTGCTTTGGGATTTAATTTCCAGGGTTGCTTGATCATTATATCATTGGAACAACTGATACTTCACTACTTTAATAAAGAATTAACAGAGATTGAAC TCCAAGAGGTGGGTAATTTGGTTTAAAAATACATGTTCATGGGTTTACCACTAACTCCTGAGAAATGTTAAAGGTTCACAGGGGTTCCCTTCTCTCAATG TTTGTAATAATTGCTCATAAGCAATACCAGCAATTCATAAAAACTGCTTACTTATGCCATAGAAAATTAAACACAAAGTGTATACATGTATTATGCTTCT AAATGCTCATTCTACCAGATACACATTTAAAAGAGAAAAAAGGAACAGAAACAAGTCATTTGAGAGTGGAGACTTATAAGAAGGAGTACATTTGAGTTGA ATACACAAATCTTTACTTCTCTACCAATTCCTATTCCCAAAATGAACATATTACTGGGGAAAGTTAGTTGAGAATCAGAGCATATGTTATTGGGGAAAGG ATATGTTTATTGACACATAATCTGTACCAGGTATGCATTAAAATATATTTGTTAATTTAATATTTAAACCTGAGAGATAGGTATTGTTTCCCAGATGAGG ACAATGAGGCAAAGAAATATCAAGTAACTTGCCAAAGGTTACAAGATATTCATTCCATGGATGCACAAAGAAGTGCATCTAGTTCCACAGCTGATTATGG TTGTCTTGCTTTTCTTCCCATTGCACCAGCTTGTCCTCCAAAATCATGAATGATACACATGAAGATAACTTTTTTTAAAAAAAAGCAGAAATACACAATG ATCTCCCTTGTAAGCTCCTAAGGTGGCTTTTCTTTCTCTAACTTCTAGTAAATATAAACGGTTTGTTTGAAAACTATTTTAAAATGTCAACAATATGGAG AATAACCCCCCCCAACACACCTATAAAAACCCAAATTTTTGGAACAAAGATAATGGAACCTCCATTTTCAAACTGAAGCACAGGGACAGAAAATATATTT CTAGTTATCACTTAAGCACTCAATCATTAGAGGCTACAAGAATAATATTTTTAAAGTTACAGTATTTTACAATTATTAGAAAACATTCTATATAAAAGAA GTCAGTTGATACTTTAAAATCTCCCATTTGGTTTATAAAATCCCTTAATTTGACCTCTATATCTTAAATTCCAAGATGTTTAAATTTGCTAGTTGCATTA TACTGGGTCATGAAAAATTATCCCTTGAAATAGATATGAAACATGTTACTTCATTTCTGGTTTAAATAACTTGTGGAATCTTTCCTAATGACAACCTGAT ATTAAGGGAAACTAAAGAAAATGTTATTGTGGATCCCACAGTACTATATTACACTGTTTTTTTTGTTTGTTTTGTTAGTTTTTTTTATTTAAAGCAAACC TCAAACATTATTGGGTATCAATTACCACCTGGTTGTATTGAAATAGTAACTTATCAATGCCATGTAAAAATTAATTCCATTTTCGAAGCCACCTGGCAGA CAGGTTTAGCTGTTTCATCAGCAGCCTAATATATACTGTTAAATTTGTTAAGGATTTCACTTTGAAGGATACATGCAAAACATATAGTTACTATTTTCAT GAGTCCTGCTTCTAGCTCCATTGTGGAATACAGAAAATTAAATATACCTGTTAAGTTCGTATCTAAACCTAAGACATTACCAAGGTTTGTACAAATTCTA CTACCTGACATTTATTCCAAGAAGATCTGGAAAGTTAAATAAATTTATAAATTTAATAACA

refseq_CDKN2B.F2 (forward primer)
refseq_CDKN2B.R2 (reverse primer)
Alternative donor

Frame 0

GSPLCQSEAGQ*GLRDASAPCGQSGFELGCVRA RRFFPEAIQARPLVLERQEKPGANDRPLGHCTGP QAAEGRREGNEAEPRSPRKERVRRSSVGKKGRV SLSLRPTVDYPGRCASGGCGMREENKGMPSGGG SDEGLASAAARGLVEKVRQLLEAGADPNGVNRFG RRAIQVMMMGSARVAELLLLHGAEPNCADPATL TRPVHDAAREGFLDTLVVLHRAGARLDVRDAWG RLPVDLAEERGHRDVAGYLRTATGD*RQVPQPPT TTLFSYPISHPHPPNSMKAANGERRKACKPASL SETHRKEEPTGNNLPYIFFFVLSGPRHSP*SET QRSGFPGIFRSV*HSRGRLLFRVF*GKVHMKSLT GPGGYESSDG*ISHSSAEWEKAVISTWVTAVDA FTPMSAEELW*THNLGPSGRKENLKTEDKVEEG RGGLQ*VPGGALV*AHGKSHA*TTLSGSPGDPRP TPPDSRGVREDVQATTDAKIPGSRRCRAPLHRM LAFALTTLRRDSRGFRRQTTQDEVVEWSESNCN G*L*RFLSHTHTHTHTHMLGCGNPLMTCYFLIL* YFVLFSCSATVLFNGEILSNITSGSQLKCEEEL QLLNVAMALLQTQCKRLDCFLLNLFISLLNFSD CFLYRVSQGAEVRLRNIPNVF*KIDALMQ*IILG *FPKDC*KSRLSIKT*KYMMARGMSYYH*TN*R CTALGFNFQGCLIIISLEQLILHYFNKELTEIE LQEVGNLV*KYMFMGLPLTPEKC*RFTGVPFSQC L**LLISNTSNS*KLLTYAIEN*TQSVYMYYAS KCSFYQIHI*KRKKEQKQVI*EWRLIRRSTFEL NTQIFTSLPIPIPKMNILLGKVS*ESEHMLLGKG YVY*HIICTRYALKYIC*FNI*T*EIGIVSQMR TMRQRNIK*LAKGYKIFIPWMHKEVHLVPQLIM VVLLFFPLHQLVLQNHE*YT*R*LFLKKSRNTQ* SPL*APKVAFLSLTSSKYKRFV*KLF*NVNNME NNPPQHTYKNPNFWNKDNGTSIFKLKHRDRKYI SSYHLSTQSLEATRIIFLKLQYFTIIRKHSI*KK SVDTLKSPIWFIKSLNLTSIS*IPRCLNLLVAL YWVMKNYPLK*I*NMLLHFWFK*LVESFLMTT* Y*GKLKKMLLWIPQYYITLFFLFVLLVFFI*SKP QTLLGINYHLVVLK**LINAM*KLIPFSKPPGR QV*LFHQQPNIYC*IC*GFHFEGYMQNI*LLFS *VLLLAPLWNTEN*IYLLSSYLNLRHYQGLYKFY YLTFIPRRSGKLNKFINLIT

Frame 1

APHSARARRGSEDSATRPHPAARAALSSAASAL GAFSQKQSRRARWFLSARKSPELTTGRSATARG PKPQKDDGRVMKLSPGLLGRRECAGAAWERREEC R*VYGQRWIIRAAARLGAAECARRTRACPVGAA AMRVWPAPRRGD*WRRCDSSWKPARIPTESTVS GGARSRS**WAAPAWRSCCCSTARSPTAQTLPLS PDRCMMLPGRASWTRWWCCTGPGRGWTCAMPGV VCPWTWPRSGATATLQGTCAQPRGTDARFPSRP QRLYFLTQFPTPTHLIR*RLPTGSGGKPVSLQAC LRLTGRRSRPGITFHTFFSLSYLALDTHHEAKH READFQGYLGVCDIPGVVCFSGFSEGKCI*NP* LDLVATNLPMDESPTPALSGRRQ*LALG*RQSMR SLQCLLRSYGEPTT*ALAAERKT*RLRTKWRRA EVGFSKSPAAL*FERMASHMRKRHSLEALETLA QLHQIAEG*ERMCKRRQMLKSLDHDAAEHLCTGC WPLLLLH*GEIPAGSAGRLHRMRWWSGVRAIVT VNCNVFFHTHTHTHTHTC*DAEIPL*LATF*FC DILYFLVVQQLSYLMGRF*VT*LVALS*NVRKNY SS*M*QWHCCKLSANA*IAFFLTYLFLC*IFLI VSFIECLRVQRSD*EIFQMSFRR*MHLCSKLSW DSSQKIAEKVD*V*KLENI*WLVGCPTITEQTKG ALLWDLISRVA*SLYHWNN*YFTTLIKN*QRLN SKRWVIWFKNTCSWVYH*LLRNVKGSQGFPSLN VCNNCS*AIPAIHKNCLLMP*KIKHKVYTCIMLL NAHSTRYTFKREKRNRNKSFESGDL*EGVHLS* IHKSLLLYQFLFPK*TYYWGKLVENQSICYWGK DMFIDT*SVPGMH*NIFVNLIFKPER*VLFPR*G Q*GKEISSNLPKVTRYSFHGCTKKCI*FHS*LW LSCFSSHCTSLSSKIMNDTHEDNFF*KKAEIHN DLPCKLLRWLFFL*LLVNINGLFENYFKMSTIWR ITPPNTPIKTQIFGTKIMEPPFSN*STGTENIF LVIT*ALNH*RLQE*YF*SYSILQLLENILYKR SQLIL*NLPFGL*NPLI*PLYLKFQDV*IC*LHY TGS*KIIP*NRYETCYFISGLNNLWNLS**QPD IKGN*RKCYCGSHSTILHCFFCLFC*FFLFKAN LKHYWVSITTWLY*NSNLSMPCKN*FHFRSHLAD RFSCFISSLIYTVKFVKDFTLKDTCKTYSYYFH ESCF*LHCGIQKIKYTC*VRI*T*DITKVCTNS TT*HLFQEDLES*INL*I**

Frame 2

LPTLPERGGAVRTPRRVRTLRPERL*ARLRPR* ALFPRSNPGAPAGS*APGKARS*RPAARPLHGA PSRRRTTGG**S*AQVS*EGESAPEQRGKEGKS VVKFTANGGLSGPLRVWGLRNARGEQGHAQWGRQ R*GSGQRRGAGTSGEGATAPGSRRGSQRSQPFR EARDPGHDDGQRPRGGAAAAPRRGAQLRRPCHS HPTGA*CCPGGLPGHAGGAAPGRGAAGRARCLGS SARGLGRGAGPPRRCRVPAHSHGGLTPGSPAAH NDFIFLPNFPPPPT*FDEGCQRGAAESL*ACKP V*DSQEGGADRE*PSIHFFLCLIWPSTLTMKRNT EKRISRDI*ECVTFQGSFAFQGFLRESAYEILD WTWWLRIFRWMNLPLQR*VGEGSD*HLGDGSRC VHSNVC*GVMVNPQLRP*RQKGKPED*GQSGGGP RWASVSPRRRFSLSAWQVTCVNDTLWKPWRPSP NSTR*QRGKRGCASDDRC*NPWITTLQSTFAQD AGLCSYYTEERFPRVPQADYTG*GGGVE*EQL*R LTVTFSFTHTHTHTHTHARMRKSPYDLLLFDFV IFCTF*LFSNCLI*WGDFK*HN*WLSVKM*GRT TALKCSNGTVANSVQTPRLLSS*PIYFFVKFF*L FPL*SVSGCRGQTKKYSKCLLEDRCTYAVNYLG IVPKRLLKK*IEYKNLKIYDGSWDVLLSLNKLK VHCFGI*FPGLLDHYIIGTTDTSLL**RINRD*T PRGG*FGLKIHVHGFTTNS*EMLKVHRGSLLSM FVIIAHKQYQQFIKTAYLCHRKLNTKCIHVLCF *MLILPDTHLKEKKGTETSHLRVETYKKEYI*VE YTNLYFSTNSYSQNEHITGES*LRIRAYVIGER ICLLTHNLYQVCIKIYLLI*YLNLRDRYCFPDE DNEAKKYQVTCQRLQDIHSMDAQRSASSSTADYG CLAFLPIAPACPPKS*MIHMKITFFKKKQKYTM ISLVSS*GGFSFSNF**I*TVCLKTILKCQQYG E*PPPTHL*KPKFLEQR*WNLHFQTEAQGQKIYF *LSLKHSIIRGYKNNIFKVTVFYNY*KTFYIKE VS*YFKISHLVYKIP*FDLYILNSKMFKFASCI ILGHEKLSLEIDMKHVTSFLV*ITCGIFPNDNLI LRETKENVIVDPTVLYYTVFFVCFVSFFYLKQT SNIIGYQLPPGCIEIVTYQCHVKINSIFEATWQ TGLAVSSAA*YILLNLLRISL*RIHAKHIVTIFM SPASSSIVEYRKLNIPVKFVSKPKTLPRFVQIL LPDIYSKKIWKVK*IYKFNN

Sequence NM_078487

GGCTCCCCACTCTGCCAGAGCGAGGCGGGGCAGTGAGGACTCCGCGACGCGTCCGCACCCTGCGGCCAGAGCGGCTTTGAGCTCGGCTGCGTCCGCGCTA GGCGCTTTTTCCCAGAAGCAATCCAGGCGCGCCCGCTGGTTCTTGAGCGCCAGGAAAAGCCCGGAGCTAACGACCGGCCGCTCGGCCACTGCACGGGGCC CCAAGCCGCAGAAGGACGACGGGAGGGTAATGAAGCTGAGCCCAGGTCTCCTAGGAAGGAGAGAGTGCGCCGGAGCAGCGTGGGAAAGAAGGGAAGAGTG TCGTTAAGTTTACGGCCAACGGTGGATTATCCGGGCCGCTGCGCGTCTGGGGGCTGCGGAATGCGCGAGGAGAACAAGGGCATGCCCAGTGGGGGCGGCA GCGATGAGGGTCTGGCCAGCGCCGCGGCGCGGGGACTAGTGGAGAAGGTGCGACAGCTCCTGGAAGCCGGCGCGGATCCCAACGGAGTCAACCGTTTCGG GAGGCGCGCGATCCAGGTAGCTGGGGCCCCAGGGCCTCGCCGGCAGGGGGCGCGCGAACGCGGGGCGCGGCCTCGGCGGATCGGGGCTGGAACCTAGATC GCCGATGTAGATTTGTACAGGAGTCTCCGTTGGCCGGAGGTCATGATGATGGGCAGCGCCCGCGTGGCGGAGCTGCTGCTGCTCCACGGCGCGGAGCCCA ACTGCGCAGACCCTGCCACTCTCACCCGACCGGTGCATGATGCTGCCCGGGAGGGCTTCCTGGACACGCTGGTGGTGCTGCACCGGGCCGGGGCGCGGCT GGACGTGCGCGATGCCTGGGGTCGTCTGCCCGTGGACTTGGCCGAGGAGCGGGGCCACCGCGACGTTGCAGGGTACCTGCGCACAGCCACGGGGGACTGA CGCCAGGTTCCCCAGCCGCCCACAACGACTTTATTTTCTTACCCAATTTCCCACCCCCACCCACCTAATTCGATGAAGGCTGCCAACGGGGAGCGGCGGA AAGCCTGTAAGCCTGCAAGCCTGTCTGAGACTCACAGGAAGGAGGAGCCGACCGGGAATAACCTTCCATACATTTTTTTCTTTGTCTTATCTGGCCCTCG ACACTCACCATGAAGCGAAACACAGAGAAGCGGATTTCCAGGGATATTTAGGAGTGTGTGACATTCCAGGGGTCGTTTGCTTTTCAGGGTTTTCTGAGGG AAAGTGCATATGAAATCCTTGACTGGACCTGGTGGCTACGAATCTTCCGATGGATGAATCTCCCACTCCAGCGCTGAGTGGGAGAAGGCAGTGATTAGCA CTTGGGTGACGGCAGTCGATGCGTTCACTCCAATGTCTGCTGAGGAGTTATGGTGAACCCACAACTTAGGCCCTAGCGGCAGAAAGGAAAACCTGAAGAC TGAGGACAAAGTGGAGGAGGGCCGAGGTGGGCTTCAGTAAGTCCCCGGCGGCGCTTTAGTTTGAGCGCATGGCAAGTCACATGCGTAAACGACACTCTCT GGAAGCCCTGGAGACCCTCGCCCAACTCCACCAGATAGCAGAGGGGTAAGAGAGGATGTGCAAGCGACGACAGATGCTAAAATCCCTGGATCACGACGCT GCAGAGCACCTTTGCACAGGATGCTGGCCTTTGCTCTTACTACACTGAGGAGAGATTCCCGCGGGTTCCGCAGGCAGACTACACAGGATGAGGTGGTGGA GTGGAGTGAGAGCAATTGTAACGGTTAACTGTAACGTTTTCTTTCACACACACACACACACACACACACACACATGCTAGGATGCGGAAATCCCCTTATG ACTTGCTACTTTTTGATTTTGTGATATTTTGTACTTTTTAGTTGTTCAGCAACTGTCTTATTTAATGGGGAGATTTTAAGTAACATAACTAGTGGCTCTC AGTTAAAATGTGAGGAAGAACTACAGCTCTTAAATGTAGCAATGGCACTGTTGCAAACTCAGTGCAAACGCCTAGATTGCTTTCTTCTTAACCTATTTAT TTCTTTGTTAAATTTTTCTGATTGTTTCCTTTATAGAGTGTCTCAGGGTGCAGAGGTCAGACTAAGAAATATTCCAAATGTCTTTTAGAAGATAGATGCA CTTATGCAGTAAATTATCTTGGGATAGTTCCCAAAAGATTGCTGAAAAAGTAGATTGAGTATAAAAACTTGAAAATATATGATGGCTCGTGGGATGTCCT ACTATCACTGAACAAACTAAAGGTGCACTGCTTTGGGATTTAATTTCCAGGGTTGCTTGATCATTATATCATTGGAACAACTGATACTTCACTACTTTAA TAAAGAATTAACAGAGATTGAACTCCAAGAGGTGGGTAATTTGGTTTAAAAATACATGTTCATGGGTTTACCACTAACTCCTGAGAAATGTTAAAGGTTC ACAGGGGTTCCCTTCTCTCAATGTTTGTAATAATTGCTCATAAGCAATACCAGCAATTCATAAAAACTGCTTACTTATGCCATAGAAAATTAAACACAAA GTGTATACATGTATTATGCTTCTAAATGCTCATTCTACCAGATACACATTTAAAAGAGAAAAAAGGAACAGAAACAAGTCATTTGAGAGTGGAGACTTAT AAGAAGGAGTACATTTGAGTTGAATACACAAATCTTTACTTCTCTACCAATTCCTATTCCCAAAATGAACATATTACTGGGGAAAGTTAGTTGAGAATCA GAGCATATGTTATTGGGGAAAGGATATGTTTATTGACACATAATCTGTACCAGGTATGCATTAAAATATATTTGTTAATTTAATATTTAAACCTGAGAGA TAGGTATTGTTTCCCAGATGAGGACAATGAGGCAAAGAAATATCAAGTAACTTGCCAAAGGTTACAAGATATTCATTCCATGGATGCACAAAGAAGTGCA TCTAGTTCCACAGCTGATTATGGTTGTCTTGCTTTTCTTCCCATTGCACCAGCTTGTCCTCCAAAATCATGAATGATACACATGAAGATAACTTTTTTTA AAAAAAAGCAGAAATACACAATGATCTCCCTTGTAAGCTCCTAAGGTGGCTTTTCTTTCTCTAACTTCTAGTAAATATAAACGGTTTGTTTGAAAACTAT TTTAAAATGTCAACAATATGGAGAATAACCCCCCCCAACACACCTATAAAAACCCAAATTTTTGGAACAAAGATAATGGAACCTCCATTTTCAAACTGAA GCACAGGGACAGAAAATATATTTCTAGTTATCACTTAAGCACTCAATCATTAGAGGCTACAAGAATAATATTTTTAAAGTTACAGTATTTTACAATTATT AGAAAACATTCTATATAAAAGAAGTCAGTTGATACTTTAAAATCTCCCATTTGGTTTATAAAATCCCTTAATTTGACCTCTATATCTTAAATTCCAAGAT GTTTAAATTTGCTAGTTGCATTATACTGGGTCATGAAAAATTATCCCTTGAAATAGATATGAAACATGTTACTTCATTTCTGGTTTAAATAACTTGTGGA ATCTTTCCTAATGACAACCTGATATTAAGGGAAACTAAAGAAAATGTTATTGTGGATCCCACAGTACTATATTACACTGTTTTTTTTGTTTGTTTTGTTA GTTTTTTTTATTTAAAGCAAACCTCAAACATTATTGGGTATCAATTACCACCTGGTTGTATTGAAATAGTAACTTATCAATGCCATGTAAAAATTAATTC CATTTTCGAAGCCACCTGGCAGACAGGTTTAGCTGTTTCATCAGCAGCCTAATATATACTGTTAAATTTGTTAAGGATTTCACTTTGAAGGATACATGCA AAACATATAGTTACTATTTTCATGAGTCCTGCTTCTAGCTCCATTGTGGAATACAGAAAATTAAATATACCTGTTAAGTTCGTATCTAAACCTAAGACAT TACCAAGGTTTGTACAAATTCTACTACCTGACATTTATTCCAAGAAGATCTGGAAAGTTAAATAAATTTATAAATTTAATAACA

refseq_CDKN2B.F2 (forward primer)
refseq_CDKN2B.R2 (reverse primer)
Alternative donor

Frame 0

GSPLCQSEAGQ*GLRDASAPCGQSGFELGCVRA RRFFPEAIQARPLVLERQEKPGANDRPLGHCTGP QAAEGRREGNEAEPRSPRKERVRRSSVGKKGRV SLSLRPTVDYPGRCASGGCGMREENKGMPSGGG SDEGLASAAARGLVEKVRQLLEAGADPNGVNRFG RRAIQVAGAPGPRRQGARERGARPRRIGAGT*I ADVDLYRSLRWPEVMMMGSARVAELLLLHGAEP NCADPATLTRPVHDAAREGFLDTLVVLHRAGARL DVRDAWGRLPVDLAEERGHRDVAGYLRTATGD* RQVPQPPTTTLFSYPISHPHPPNSMKAANGERR KACKPASLSETHRKEEPTGNNLPYIFFFVLSGPR HSP*SETQRSGFPGIFRSV*HSRGRLLFRVF*G KVHMKSLTGPGGYESSDG*ISHSSAEWEKAVIS TWVTAVDAFTPMSAEELW*THNLGPSGRKENLKT EDKVEEGRGGLQ*VPGGALV*AHGKSHA*TTLS GSPGDPRPTPPDSRGVREDVQATTDAKIPGSRR CRAPLHRMLAFALTTLRRDSRGFRRQTTQDEVVE WSESNCNG*L*RFLSHTHTHTHTHMLGCGNPLM TCYFLIL*YFVLFSCSATVLFNGEILSNITSGS QLKCEEELQLLNVAMALLQTQCKRLDCFLLNLFI SLLNFSDCFLYRVSQGAEVRLRNIPNVF*KIDA LMQ*IILG*FPKDC*KSRLSIKT*KYMMARGMS YYH*TN*RCTALGFNFQGCLIIISLEQLILHYFN KELTEIELQEVGNLV*KYMFMGLPLTPEKC*RF TGVPFSQCL**LLISNTSNS*KLLTYAIEN*TQ SVYMYYASKCSFYQIHI*KRKKEQKQVI*EWRLI RRSTFELNTQIFTSLPIPIPKMNILLGKVS*ES EHMLLGKGYVY*HIICTRYALKYIC*FNI*T*E IGIVSQMRTMRQRNIK*LAKGYKIFIPWMHKEVH LVPQLIMVVLLFFPLHQLVLQNHE*YT*R*LFL KKSRNTQ*SPL*APKVAFLSLTSSKYKRFV*KL F*NVNNMENNPPQHTYKNPNFWNKDNGTSIFKLK HRDRKYISSYHLSTQSLEATRIIFLKLQYFTII RKHSI*KKSVDTLKSPIWFIKSLNLTSIS*IPR CLNLLVALYWVMKNYPLK*I*NMLLHFWFK*LVE SFLMTT*Y*GKLKKMLLWIPQYYITLFFLFVLL VFFI*SKPQTLLGINYHLVVLK**LINAM*KLI PFSKPPGRQV*LFHQQPNIYC*IC*GFHFEGYMQ NI*LLFS*VLLLAPLWNTEN*IYLLSSYLNLRH YQGLYKFYYLTFIPRRSGKLNKFINLIT

Frame 1

APHSARARRGSEDSATRPHPAARAALSSAASAL GAFSQKQSRRARWFLSARKSPELTTGRSATARG PKPQKDDGRVMKLSPGLLGRRECAGAAWERREEC R*VYGQRWIIRAAARLGAAECARRTRACPVGAA AMRVWPAPRRGD*WRRCDSSWKPARIPTESTVS GGARSR*LGPQGLAGRGRANAGRGLGGSGLEPRS PM*ICTGVSVGRRS**WAAPAWRSCCCSTARSP TAQTLPLSPDRCMMLPGRASWTRWWCCTGPGRG WTCAMPGVVCPWTWPRSGATATLQGTCAQPRGTD ARFPSRPQRLYFLTQFPTPTHLIR*RLPTGSGG KPVSLQACLRLTGRRSRPGITFHTFFSLSYLAL DTHHEAKHREADFQGYLGVCDIPGVVCFSGFSEG KCI*NP*LDLVATNLPMDESPTPALSGRRQ*LA LG*RQSMRSLQCLLRSYGEPTT*ALAAERKT*R LRTKWRRAEVGFSKSPAAL*FERMASHMRKRHSL EALETLAQLHQIAEG*ERMCKRRQMLKSLDHDA AEHLCTGCWPLLLLH*GEIPAGSAGRLHRMRWW SGVRAIVTVNCNVFFHTHTHTHTHTC*DAEIPL* LATF*FCDILYFLVVQQLSYLMGRF*VT*LVAL S*NVRKNYSS*M*QWHCCKLSANA*IAFFLTYL FLC*IFLIVSFIECLRVQRSD*EIFQMSFRR*MH LCSKLSWDSSQKIAEKVD*V*KLENI*WLVGCP TITEQTKGALLWDLISRVA*SLYHWNN*YFTTL IKN*QRLNSKRWVIWFKNTCSWVYH*LLRNVKGS QGFPSLNVCNNCS*AIPAIHKNCLLMP*KIKHK VYTCIMLLNAHSTRYTFKREKRNRNKSFESGDL *EGVHLS*IHKSLLLYQFLFPK*TYYWGKLVENQ SICYWGKDMFIDT*SVPGMH*NIFVNLIFKPER *VLFPR*GQ*GKEISSNLPKVTRYSFHGCTKKC I*FHS*LWLSCFSSHCTSLSSKIMNDTHEDNFF* KKAEIHNDLPCKLLRWLFFL*LLVNINGLFENY FKMSTIWRITPPNTPIKTQIFGTKIMEPPFSN* STGTENIFLVIT*ALNH*RLQE*YF*SYSILQLL ENILYKRSQLIL*NLPFGL*NPLI*PLYLKFQD V*IC*LHYTGS*KIIP*NRYETCYFISGLNNLW NLS**QPDIKGN*RKCYCGSHSTILHCFFCLFC* FFLFKANLKHYWVSITTWLY*NSNLSMPCKN*F HFRSHLADRFSCFISSLIYTVKFVKDFTLKDTC KTYSYYFHESCF*LHCGIQKIKYTC*VRI*T*DI TKVCTNSTT*HLFQEDLES*INL*I**

Frame 2

LPTLPERGGAVRTPRRVRTLRPERL*ARLRPR* ALFPRSNPGAPAGS*APGKARS*RPAARPLHGA PSRRRTTGG**S*AQVS*EGESAPEQRGKEGKS VVKFTANGGLSGPLRVWGLRNARGEQGHAQWGRQ R*GSGQRRGAGTSGEGATAPGSRRGSQRSQPFR EARDPGSWGPRASPAGGARTRGAASADRGWNLD RRCRFVQESPLAGGHDDGQRPRGGAAAAPRRGAQ LRRPCHSHPTGA*CCPGGLPGHAGGAAPGRGAA GRARCLGSSARGLGRGAGPPRRCRVPAHSHGGL TPGSPAAHNDFIFLPNFPPPPT*FDEGCQRGAAE SL*ACKPV*DSQEGGADRE*PSIHFFLCLIWPS TLTMKRNTEKRISRDI*ECVTFQGSFAFQGFLR ESAYEILDWTWWLRIFRWMNLPLQR*VGEGSD*H LGDGSRCVHSNVC*GVMVNPQLRP*RQKGKPED *GQSGGGPRWASVSPRRRFSLSAWQVTCVNDTL WKPWRPSPNSTR*QRGKRGCASDDRC*NPWITTL QSTFAQDAGLCSYYTEERFPRVPQADYTG*GGG VE*EQL*RLTVTFSFTHTHTHTHTHARMRKSPY DLLLFDFVIFCTF*LFSNCLI*WGDFK*HN*WLS VKM*GRTTALKCSNGTVANSVQTPRLLSS*PIY FFVKFF*LFPL*SVSGCRGQTKKYSKCLLEDRC TYAVNYLGIVPKRLLKK*IEYKNLKIYDGSWDVL LSLNKLKVHCFGI*FPGLLDHYIIGTTDTSLL* *RINRD*TPRGG*FGLKIHVHGFTTNS*EMLKV HRGSLLSMFVIIAHKQYQQFIKTAYLCHRKLNTK CIHVLCF*MLILPDTHLKEKKGTETSHLRVETY KKEYI*VEYTNLYFSTNSYSQNEHITGES*LRI RAYVIGERICLLTHNLYQVCIKIYLLI*YLNLRD RYCFPDEDNEAKKYQVTCQRLQDIHSMDAQRSA SSSTADYGCLAFLPIAPACPPKS*MIHMKITFF KKKQKYTMISLVSS*GGFSFSNF**I*TVCLKTI LKCQQYGE*PPPTHL*KPKFLEQR*WNLHFQTE AQGQKIYF*LSLKHSIIRGYKNNIFKVTVFYNY *KTFYIKEVS*YFKISHLVYKIP*FDLYILNSKM FKFASCIILGHEKLSLEIDMKHVTSFLV*ITCG IFPNDNLILRETKENVIVDPTVLYYTVFFVCFV SFFYLKQTSNIIGYQLPPGCIEIVTYQCHVKINS IFEATWQTGLAVSSAA*YILLNLLRISL*RIHA KHIVTIFMSPASSSIVEYRKLNIPVKFVSKPKT LPRFVQILLPDIYSKKIWKVK*IYKFNN