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Sequences

Sequence NM_183393

ACAGCTTGCAACACTCGGCATCTTTTCTGGAGGCGCCTCCTTCAGCAGCCGCAGATGGCATCCGGCTGCGGGCTCGGGGCTCGCAATTGATTCTCCCCCT
TGCCCACCTCGAGTCCACGGACGCACCTCTCCCTTCCCCTCCTCCCTTCGCGCTTCTGGGTCTGAGCCCAGCTCGCGACCGCCGGGCAGAGGATCAGTCG
CGGCGGCCGAGGCTGAGCAGCAGCGCTCTCGCTCCCTGACCTGGGGAGAAGCGCCCACCCGGGAGAGCTGATCCCCGGCTGCCTCCAGCGCCCCCCACCT
TTTGCACTCCAAGCCGGGGGCTCCAGAGACCCCGCTCCCCAGGCGCCACTATGCTGGACCCTTCGTCCAGCGAAGAAGAATCGGATGAGATCGTGGAGGA
GGAGAGCGGCAAGGAGGTGCTCGGCTCGGCCCCGTCCGGCGCGCGCCTGTCTCCCAGCCGTACCAGCGAGGGCTCGGCCGGCAGCGCCGGGCTGGGGGGC
GGCGGCGCCGGCGCCGGAGCCGGGGTGGGTGCAGGCGGCGGCGGGGGCAGCGGCGCGAGCAGCGGCGGCGGGGCCGGGGGGCTGCAACCCAGCAGCCGCG
CTGGCGGCGGCCGGCCCTCCAGCCCCAGCCCGTCGGTGGTGAGCGAGAAGGAGAAGGAAGAGTTGGAGCGGCTGCAGAAAGAGGAGGAGGAGAGGAAGAA
GAGGCTGCAGCTGTATGTGTTCGTGATGCGCTGCATCGCCTACCCCTTTAATGCCAAGCAGCCCACCGACATGGCTCGCCGGCAGCAGAAGATCAGCAAA
CAGCAGCTGCAGACAGTCAAGGACCGGTTTCAGGCTTTCCTCAATGGGGAAACCCAGATCATGGCTGACGAAGCCTTCATGAACGCTGTGCAGAGTTACT
ATGAGGTGTTCCTGAAGAGCGACCGTGTGGCCCGCATGGTTCAGAGTGGAGGCTGTTCCGCCAACGACTCCCGGGAGGTCTTCAAGAAGCACATTGAGAA
GAGAGTGCGCAGCCTGCCTGAGATTGACGGCCTCAGCAAGGAGACTGTGCTGAGCTCCTGGATGGCCAAATTTGATGCCATCTACCGTGGAGAAGAGGAC
CCGCGGAAGCAGCAGGCCCGGATGACAGCCAGCGCAGCCTCCGAGCTGATTCTGAGCAAGGAGCAACTCTATGAGATGTTCCAGAACATTCTTGGGATCA
AGAAGTTCGAACATCAGCTCCTTTACAATGCCTGCCAGCTGGACAATCCAGATGAGCAAGCAGCCCAGATCAGACGAGAGCTGGATGGACGTCTACAAAT
GGCAGACCAAATAGCCAGGGAACGCAAATTTCCCAAGTTTGTATCCAAAGAAATGGAAAACATGTACATTGAGGAGCTGAAGTCATCTGTCAACCTGCTC
ATGGCCAACTTGGAGAGCATGCCGGTATCCAAAGGCGGGGAGTTCAAGCTCCAGAAACTCAAACGCAGCCACAATGCTTCCATCATCGACATGGGCGAGG
AGAGTGAGAACCAGCTCTCCAAGTCAGATGTCGTGCTGTCTTTCTCATTGGAGGTGGTAATTATGGAAGTCCAAGGCCTCAAATCTTTGGCTCCAAATCG
CATCGTATATTGCACAATGGAGGTGGAAGGAGGAGAGAAACTACAGACTGATCAGGCCGAGGCTTCTAAACCAACCTGGGGCACCCAGGGTGACTTCTCC
ACAACCCATGCACTGCCAGCTGTGAAGGTGAAGCTGTTCACAGAGAGCACAGGCGTCCTGGCGTTGGAGGACAAGGAGCTTGGGCGGGTTATTCTCCATC
CCACCCCGAACAGCCCCAAACAGTCAGAGTGGCACAAAATGACAGTCTCCAAAAACTGCCCCGACCAAGATCTCAAAATCAAACTTGCTGTCCGAATGGA
TAAGCCTCAAAACATGAAGCATTCTGGGTATTTATGGGCCATCGGTAAGAATGTCTGGAAGAGATGGAAGAAAAGGTTTTTTGTATTGGTGCAGGTCAGT
CAGTACACGTTTGCCATGTGCAGTTATCGGGAGAAGAAAGCGGAGCCTCAGGAACTTCTACAATTGGATGGCTACACTGTGGATTACACCGACCCCCAGC
CAGGTTTGGAGGGTGGCCGAGCCTTCTTCAATGCTGTCAAGGAGGGAGACACCGTGATATTTGCCAGTGACGATGAACAAGACCGCATCCTGTGGGTCCA
GGCCATGTATCGGGCCACGGGGCAGTCACACAAGCCTGTGCCCCCGACCCAAGTCCAGAAACTCAACGCCAAGGGAGGAAATGTACCTCAGCTGGATGCC
CCTATCTCTCAATTTTACGCAGATAGAGCTCAAAAACATGGCATGGATGAATTTATCTCTTCCAACCCCTGTAACTTTGACCACGCTTCCCTCTTTGAGA
TG
GGCTGGTTCAGTCCTGGCCAGGTGTTTGTACTAGACGAGTATTGCGCCCGAAATGGAGTCCGGGGGTGTCACCGACATCTCTGCTACCTCAGAGACTT
GCTTGAACGGGCAGAAAATGGCGCCATGATCGACCCCACCCTTCTTCACTACAGCTTTGCCTTCTGTGCATCCCATGTCCATGGGAACAGGCCTGATGGA
ATTGGAACTGTGACTGTTGAAGAAAAGGAACGTTTTGAAGAAATCAAAGAGAGGCTCCGAGTTCTGCTAGAAAATCAGATTACACATTTTAGGTATTGCT
TTCCATTTGGTCGACCTGAAGGTGCTTTGAAAGCTACTCTCTCACTCTTGGAAAGGGTTTTGATGAAAGATATTGTTACCCCAGTGCCACAAGAGGAGGT
AAAAACAGTTATCCGTAAATGTCTGGAACAGGCTGCGTTAGTCAACTATTCTCGGCTCTCAGAGTATGCCAAAATCGAAGAAAATGTAGGCCGGTTAATC
ACTCCTGCCAAAAAGCTTGAAGATACAATACGTCTTGCTGAACTAGTCATTGAAGTTCTTCAGCAAAATGAGGAGCACCACGCAGAGGCCTTTGCGTGGT
GGTCAGATTTAATGGTGGAGCATGCGGAGACGTTCCTGTCACTCTTTGCAGTAGACATGGATGCAGCCTTAGAGGTGCAACCTCCAGACACATGGGACAG
TTTTCCACTATTTCAGCTGCTGAATGATTTTCTCCGTACTGACTATAATTTGTGCAATGGAAAATTTCACAAACACCTGCAAGACCTGTTTGCCCCACTT
GTTGTTAGATATGTGGATCTGATGGAGTCCTCAATTGCACAATCCATTCACAGGGGCTTTGAGCGGGAGTCATGGGAACCAGTCAATAATGGGTCAGGCA
CCTCAGAAGATCTGTTTTGGAAACTTGACGCCCTTCAGACCTTCATTCGGGACCTGCACTGGCCTGAAGAAGAGTTTGGAAAGCACCTGGAACAACGGCT
GAAGTTGATGGCAAGTGACATGATCGAATCTTGTGTCAAAAGAACCAGGATTGCATTTGAAGTTAAGCTGCAAAAAACCAGTCGATCAACAGATTTTCGA
GTCCCACAGTCAATATGCACCATGTTTAATGTTATGGTTGATGCCAAAGCTCAATCAACAAAACTTTGCAGCATGGAAATGGGCCAAGAGCATCAATACC
ATTCAAAAATAGACGAACTAATTGAAGAAACTGTTAAAGAAATGATAACACTCTTGGTTGCAAAGTTCGTTACTATCTTGGAAGGAGTGCTGGCAAAATT
ATCCAGATATGACGAAGGGACTTTGTTTTCTTCTTTTCTGTCATTTACCGTGAAGGCAGCTTCCAAATATGTGGATGTACCTAAACCCGGGATGGACGTG
GCCGACGCCTACGTGACTTTCGTCCGCCATTCTCAGGATGTCCTGCGTGATAAGGTCAATGAGGAGATGTACATAGAAAGGTTATTTGATCAATGGTACA
ACAGCTCCATGAACGTGATCTGCACCTGGTTGACGGACCGGATGGACTTACAGCTTCATATTTATCAGTTGAAAACACTAATTAGGATGGTAAAGAAAAC
CTACAGAGATTTCCGATTGCAAGGGGTCCTGGACTCCACCTTAAACAGCAAGACCTATGAAACGATCCGGAACCGTCTCACTGTGGAGGAAGCCACAGCA
TCAGTGAGTGAAGGTGGGGGACTGCAGGGCATCAGCATGAAGGACAGCGATGAGGAAGACGAAGAAGACGATTAGACCATTTGGTCCTAGAGTCTGCTGG
GACAGAGTCCTGTAATCAGTGCATGTCCTTAGTCTGTTAGTTAAACCCATTAGGAATTTTCTGTCAACTACCATGCCCATGAGATGTTTATCAATACAAC
TGCCATTTTAGCTATGTGGTACCAAGATTAGCAAATGACCTTCATATCCACTGATTTCCTGATGTCCATGTCTATATGTTTACAAGCAATATGGAGCACC
ATTCTTTAAATACTGTTCATGGAGAATACATAGTCTAACCACTAGGCGTGTCCCTGTTATCAGCAAAGATCAATGATGCTTCATTCATGTACTATGTATG
CATTGGTGGTAAATGGATGTGAGGGCAAGTACATCAAGTACATTCACTCTGTTTCACGTATGTGGATGCCAGTTAATTAAATGAGTACGTAAATAAATTA
ATTAAAACACATAGATCTGCTTTGTGTTTTTATTTTTATTTTTTGAAAAACAAAAGGCAAGTCTCCAACAATTAACTTTTGATGCTTTCTGTTCCCCTAA
AACCAAAAAATGAACCCCTTGTGTCGTTGTTAACCCATCCTTTCATTTACTCATATAATTAGCCAAAAAAAAAAGGATGGCTACATACCAATGGATTGAT
TCTCTTAATTGCCACGGCAAGGGGGCGATCCTATCATGACTTAACATCAAGCGCGCAGTTCAAAACTACTGTCTTCTGTCAAAGTTTTCTCCTCTTAAAT
GTTATTTTGCTTTTACGTCTCAACTGTGTATGTAAAAAAAATGAATATTTAAATTACAACCCTAGACTAAAAATGTGTTTATAATAAGATGTGGATATTT
CCTTCAGTAGATTGTAACCATAATTTAAATTATTTTGTTCCACACTGTTTTTTATATCTGTCATGTACATTGCATTTTGATCTGTAACTGCACAACCCTG
GGGTTTGCTGCAGAGCTATTTCTTTCCATGTAAAGTAGTGGATCCATCTTGCTTTTGCCTTATATAAAGCCTACAGTTATGGAAGTGTGGAAAACTGTGG
CTTCTCAATAAATATTCAGATGTCCTAAGAATATA
  • refseq_CADPS.F4 (forward primer)
  • refseq_CADPS.R4 (reverse primer)
  • Alternative donor

Frame 0

TACNTRHLFWRRLLQQPQMASGCGLGARN*FSP
LPTSSPRTHLSLPLLPSRFWV*AQLATAGQRISR
GGRG*AAALSLPDLGRSAHPGELIPGCLQRPPP
FALQAGGSRDPAPQAPLCWTLRPAKKNRMRSWR
RRAARRCSARPRPARACLPAVPARARPAAPGWGA
AAPAPEPGWVQAAAGAAARAAAAGPGGCNPAAA
LAAAGPPAPARRW*ARRRRKSWSGCRKRRRRGR
RGCSCMCS*CAASPTPLMPSSPPTWLAGSRRSAN
SSCRQSRTGFRLSSMGKPRSWLTKPS*TLCRVT
MRCS*RATVWPAWFRVEAVPPTTPGRSSRSTLR
RECAACLRLTASARRLC*APGWPNLMPSTVEKRT
RGSSRPG*QPAQPPS*F*ARSNSMRCSRTFLGS
RSSNISSFTMPASWTIQMSKQPRSDESWMDVYK
WQTK*PGNANFPSLYPKKWKTCTLRS*SHLSTCS
WPTWRACRYPKAGSSSSRNSNAATMLPSSTWAR
RVRTSSPSQMSCCLSHWRW*LWKSKASNLWLQI
ASYIAQWRWKEERNYRLIRPRLLNQPGAPRVTSP
QPMHCQL*R*SCSQRAQASWRWRTRSLGGLFSI
PPRTAPNSQSGTK*QSPKTAPTKISKSNLLSEW
ISLKT*SILGIYGPSVRMSGRDGRKGFLYWCRSV
STRLPCAVIGRRKRSLRNFYNWMATLWITPTPS
QVWRVAEPSSMLSRRETP*YLPVTMNKTASCGS
RPCIGPRGSHTSLCPRPKSRNSTPREEMYLSWMP
LSLNFTQIELKNMAWMNLSLPTPVTLTTLPSLR
W
AGSVLARCLY*TSIAPEMESGGVTDISATSET
CLNGQKMAP*STPPFFTTALPSVHPMSMGTGLME
LEL*LLKKRNVLKKSKRGSEFC*KIRLHILGIA
FHLVDLKVL*KLLSHSWKGF**KILLPQCHKRR
*KQLSVNVWNRLR*STILGSQSMPKSKKM*AG*S
LLPKSLKIQYVLLN*SLKFFSKMRSTTQRPLRG
GQI*WWSMRRRSCHSLQ*TWMQP*RCNLQTHGT
VFHYFSC*MIFSVLTIICAMENFTNTCKTCLPHL
LLDMWI*WSPQLHNPFTGALSGSHGNQSIMGQA
PQKICFGNLTPFRPSFGTCTGLKKSLESTWNNG
*S*WQVT*SNLVSKEPGLHLKLSCKKPVDQQIFE
SHSQYAPCLMLWLMPKLNQQNFAAWKWAKSINT
IQK*TN*LKKLLKK**HSWLQSSLLSWKECWQN
YPDMTKGLCFLLFCHLP*RQLPNMWMYLNPGWTW
PTPT*LSSAILRMSCVIRSMRRCT*KGYLINGT
TAP*T*SAPG*RTGWTYSFIFIS*KH*LGW*RK
PTEISDCKGSWTPP*TARPMKRSGTVSLWRKPQH
Q*VKVGDCRASA*RTAMRKTKKTIRPFGPRVCW
DRVL*SVHVLSLLVKPIRNFLSTTMPMRCLSIQ
LPF*LCGTKISK*PSYPLIS*CPCLYVYKQYGAP
FFKYCSWRIHSLTTRRVPVISKDQ*CFIHVLCM
HWW*MDVRASTSSTFTLFHVCGCQLIK*VRK*I
N*NT*ICFVFLFLFFEKQKASLQQLTFDAFCSPK
TKK*TPCVVVNPSFHLLI*LAKKKRMATYQWID
SLNCHGKGAILS*LNIKRAVQNYCLLSKFSPLK
CYFAFTSQLCM*KK*IFKLQP*TKNVFIIRCGYF
LQ*IVTII*IILFHTVFYICHVHCILICNCTTL
GFAAELFLSM*SSGSILLLPYIKPTVMEVWKTV
ASQ*IFRCPKNI

Frame 1

QLATLGIFSGGASFSSRRWHPAAGSGLAIDSPP
CPPRVHGRTSPFPSSLRASGSEPSSRPPGRGSV
AAAEAEQQRSRSLTWGEAPTRES*SPAASSAPHL
LHSKPGAPETPLPRRHYAGPFVQRRRIG*DRGG
GERQGGARLGPVRRAPVSQPYQRGLGRQRRAGG
RRRRRRSRGGCRRRRGQRREQRRRGRGAATQQPR
WRRPALQPQPVGGEREGEGRVGAAAERGGGEEE
EAAAVCVRDALHRLPL*CQAAHRHGSPAAEDQQ
TAAADSQGPVSGFPQWGNPDHG*RSLHERCAELL
*GVPEERPCGPHGSEWRLFRQRLPGGLQEAH*E
ESAQPA*D*RPQQGDCAELLDGQI*CHLPWRRG
PAEAAGPDDSQRSLRADSEQGATL*DVPEHSWDQ
EVRTSAPLQCLPAGQSR*ASSPDQTRAGWTSTN
GRPNSQGTQISQVCIQRNGKHVH*GAEVICQPA
HGQLGEHAGIQRRGVQAPETQTQPQCFHHRHGRG
E*EPALQVRCRAVFLIGGGNYGSPRPQIFGSKS
HRILHNGGGRRRETTD*SGRGF*TNLGHPG*LL
HNPCTASCEGEAVHREHRRPGVGGQGAWAGYSPS
HPEQPQTVRVAQNDSLQKLPRPRSQNQTCCPNG
*ASKHEAFWVFMGHR*ECLEEMEEKVFCIGAGQ
SVHVCHVQLSGEESGASGTSTIGWLHCGLHRPPA
RFGGWPSLLQCCQGGRHRDICQ*R*TRPHPVGP
GHVSGHGAVTQACAPDPSPETQRQGRKCTSAGC
PYLSILRR*SSKTWHG*IYLFQPL*L*PRFPL*D
GLVQSWPGVCTRRVLRPKWSPGVSPTSLLPQRL
A*TGRKWRHDRPHPSSLQLCLLCIPCPWEQA*W
NWNCDC*RKGTF*RNQREAPSSARKSDYTF*VLL
SIWST*RCFESYSLTLGKGFDERYCYPSATRGG
KNSYP*MSGTGCVSQLFSALRVCQNRRKCRPVN
HSCQKA*RYNTSC*TSH*SSSAK*GAPRRGLCVV
VRFNGGACGDVPVTLCSRHGCSLRGATSRHMGQ
FSTISAAE*FSPY*L*FVQWKISQTPARPVCPT
CC*ICGSDGVLNCTIHSQGL*AGVMGTSQ*WVRH
LRRSVLET*RPSDLHSGPALA*RRVWKAPGTTA
EVDGK*HDRILCQKNQDCI*S*AAKNQSINRFS
SPTVNMHHV*CYG*CQSSINKTLQHGNGPRASIP
FKNRRTN*RNC*RNDNTLGCKVRYYLGRSAGKI
IQI*RRDFVFFFSVIYREGSFQICGCT*TRDGR
GRRLRDFRPPFSGCPA**GQ*GDVHRKVI*SMVQ
QLHERDLHLVDGPDGLTASYLSVENTN*DGKEN
LQRFPIARGPGLHLKQQDL*NDPEPSHCGGSHS
ISE*RWGTAGHQHEGQR*GRRRRRLDHLVLESAG
TESCNQCMSLVC*LNPLGIFCQLPCP*DVYQYN
CHFSYVVPRLANDLHIH*FPDVHVYMFTSNMEH
HSLNTVHGEYIV*PLGVSLLSAKINDASFMYYVC
IGGKWM*GQVHQVHSLCFTYVDAS*LNEYVNKL
IKTHRSALCFYFYFLKNKRQVSNN*LLMLSVPL
KPKNEPLVSLLTHPFIYSYN*PKKKGWLHTNGLI
LLIATARGRSYHDLTSSAQFKTTVFCQSFLLLN
VILLLRLNCVCKKNEYLNYNPRLKMCL**DVDI
SFSRL*P*FKLFCSTLFFISVMYIAF*SVTAQPW
GLLQSYFFPCKVVDPSCFCLI*SLQLWKCGKLW
LLNKYSDVLRI

Frame 2

SLQHSASFLEAPPSAAADGIRLRARGSQLILPL
AHLESTDAPLPSPPPFALLGLSPARDRRAEDQS
RRPRLSSSALAP*PGEKRPPGRADPRLPPAPPT
FCTPSRGLQRPRSPGATMLDPSSSEEESDEIVEE
ESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGG
GGAGAGAGVGAGGGGGSGASSGGGAGGLQPSSR
AGGGRPSSPSPSVVSEKEKEELERLQKEEEERKK
RLQLYVFVMRCIAYPFNAKQPTDMARRQQKISK
QQLQTVKDRFQAFLNGETQIMADEAFMNAVQSY
YEVFLKSDRVARMVQSGGCSANDSREVFKKHIEK
RVRSLPEIDGLSKETVLSSWMAKFDAIYRGEED
PRKQQARMTASAASELILSKEQLYEMFQNILGI
KKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQM
ADQIARERKFPKFVSKEMENMYIEELKSSVNLL
MANLESMPVSKGGEFKLQKLKRSHNASIIDMGE
ESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNR
IVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFS
TTHALPAVKVKLFTESTGVLALEDKELGRVILH
PTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMD
KPQNMKHSGYLWAIGKNVWKRWKKRFFVLVQVS
QYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQ
PGLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQ
AMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDA
PISQFYADRAQKHGMDEFISSNPCNFDHASLFE
M
GWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDL
LERAENGAMIDPTLLHYSFAFCASHVHGNRPDG
IGTVTVEEKERFEEIKERLRVLLENQITHFRYC
FPFGRPEGALKATLSLLERVLMKDIVTPVPQEEV
KTVIRKCLEQAALVNYSRLSEYAKIEENVGRLI
TPAKKLEDTIRLAELVIEVLQQNEEHHAEAFAW
WSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDS
FPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPL
VVRYVDLMESSIAQSIHRGFERESWEPVNNGSG
TSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRL
KLMASDMIESCVKRTRIAFEVKLQKTSRSTDFR
VPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQY
HSKIDELIEETVKEMITLLVAKFVTILEGVLAKL
SRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDV
ADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWY
NSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKT
YRDFRLQGVLDSTLNSKTYETIRNRLTVEEATA
SVSEGGGLQGISMKDSDEEDEEDD*TIWS*SLL
GQSPVISACP*SVS*TH*EFSVNYHAHEMFINTT
AILAMWYQD*QMTFISTDFLMSMSICLQAIWST
IL*ILFMENT*SNH*ACPCYQQRSMMLHSCTMY
ALVVNGCEGKYIKYIHSVSRMWMPVN*MST*IN*
LKHIDLLCVFIFIF*KTKGKSPTINF*CFLFP*
NQKMNPLCRC*PILSFTHIISQKKKDGYIPMD*
FS*LPRQGGDPIMT*HQARSSKLLSSVKVFSS*M
LFCFYVSTVYVKKMNI*ITTLD*KCVYNKMWIF
PSVDCNHNLNYFVPHCFLYLSCTLHFDL*LHNP
GVCCRAISFHVK*WIHLAFALYKAYSYGSVENCG
FSINIQMS*EY

Sequence NM_183394

ACAGCTTGCAACACTCGGCATCTTTTCTGGAGGCGCCTCCTTCAGCAGCCGCAGATGGCATCCGGCTGCGGGCTCGGGGCTCGCAATTGATTCTCCCCCT
TGCCCACCTCGAGTCCACGGACGCACCTCTCCCTTCCCCTCCTCCCTTCGCGCTTCTGGGTCTGAGCCCAGCTCGCGACCGCCGGGCAGAGGATCAGTCG
CGGCGGCCGAGGCTGAGCAGCAGCGCTCTCGCTCCCTGACCTGGGGAGAAGCGCCCACCCGGGAGAGCTGATCCCCGGCTGCCTCCAGCGCCCCCCACCT
TTTGCACTCCAAGCCGGGGGCTCCAGAGACCCCGCTCCCCAGGCGCCACTATGCTGGACCCTTCGTCCAGCGAAGAAGAATCGGATGAGATCGTGGAGGA
GGAGAGCGGCAAGGAGGTGCTCGGCTCGGCCCCGTCCGGCGCGCGCCTGTCTCCCAGCCGTACCAGCGAGGGCTCGGCCGGCAGCGCCGGGCTGGGGGGC
GGCGGCGCCGGCGCCGGAGCCGGGGTGGGTGCAGGCGGCGGCGGGGGCAGCGGCGCGAGCAGCGGCGGCGGGGCCGGGGGGCTGCAACCCAGCAGCCGCG
CTGGCGGCGGCCGGCCCTCCAGCCCCAGCCCGTCGGTGGTGAGCGAGAAGGAGAAGGAAGAGTTGGAGCGGCTGCAGAAAGAGGAGGAGGAGAGGAAGAA
GAGGCTGCAGCTGTATGTGTTCGTGATGCGCTGCATCGCCTACCCCTTTAATGCCAAGCAGCCCACCGACATGGCTCGCCGGCAGCAGAAGATCAGCAAA
CAGCAGCTGCAGACAGTCAAGGACCGGTTTCAGGCTTTCCTCAATGGGGAAACCCAGATCATGGCTGACGAAGCCTTCATGAACGCTGTGCAGAGTTACT
ATGAGGTGTTCCTGAAGAGCGACCGTGTGGCCCGCATGGTTCAGAGTGGAGGCTGTTCCGCCAACGACTCCCGGGAGGTCTTCAAGAAGCACATTGAGAA
GAGAGTGCGCAGCCTGCCTGAGATTGACGGCCTCAGCAAGGAGACTGTGCTGAGCTCCTGGATGGCCAAATTTGATGCCATCTACCGTGGAGAAGAGGAC
CCGCGGAAGCAGCAGGCCCGGATGACAGCCAGCGCAGCCTCCGAGCTGATTCTGAGCAAGGAGCAACTCTATGAGATGTTCCAGAACATTCTTGGGATCA
AGAAGTTCGAACATCAGCTCCTTTACAATGCCTGCCAGCTGGACAATCCAGATGAGCAAGCAGCCCAGATCAGACGAGAGCTGGATGGACGTCTACAAAT
GGCAGACCAAATAGCCAGGGAACGCAAATTTCCCAAGTTTGTATCCAAAGAAATGGAAAACATGTACATTGAGGAGCTGAAGTCATCTGTCAACCTGCTC
ATGGCCAACTTGGAGAGCATGCCGGTATCCAAAGGCGGGGAGTTCAAGCTCCAGAAACTCAAACGCAGCCACAATGCTTCCATCATCGACATGGGCGAGG
AGAGTGAGAACCAGCTCTCCAAGTCAGATGTCGTGCTGTCTTTCTCATTGGAGGTGGTAATTATGGAAGTCCAAGGCCTCAAATCTTTGGCTCCAAATCG
CATCGTATATTGCACAATGGAGGTGGAAGGAGGAGAGAAACTACAGACTGATCAGGCCGAGGCTTCTAAACCAACCTGGGGCACCCAGGGTGACTTCTCC
ACAACCCATGCACTGCCAGCTGTGAAGGTGAAGCTGTTCACAGAGAGCACAGGCGTCCTGGCGTTGGAGGACAAGGAGCTTGGGCGGGTTATTCTCCATC
CCACCCCGAACAGCCCCAAACAGTCAGAGTGGCACAAAATGACAGTCTCCAAAAACTGCCCCGACCAAGATCTCAAAATCAAACTTGCTGTCCGAATGGA
TAAGCCTCAAAACATGAAGCATTCTGGGTATTTATGGGCCATCGGTAAGAATGTCTGGAAGAGATGGAAGAAAAGGTTTTTTGTATTGGTGCAGGTCAGT
CAGTACACGTTTGCCATGTGCAGTTATCGGGAGAAGAAAGCGGAGCCTCAGGAACTTCTACAATTGGATGGCTACACTGTGGATTACACCGACCCCCAGC
CAGGTTTGGAGGGTGGCCGAGCCTTCTTCAATGCTGTCAAGGAGGGAGACACCGTGATATTTGCCAGTGACGATGAACAAGACCGCATCCTGTGGGTCCA
GGCCATGTATCGGGCCACGGGGCAGTCACACAAGCCTGTGCCCCCGACCCAAGTCCAGAAACTCAACGCCAAGGGAGGAAATGTACCTCAGCTGGATGCC
CCTATCTCTCAATTTTACGCAGATAGAGCTCAAAAACATGGCATGGATGAATTTATCTCTTCCAACCCCTGTAACTTTGACCACGCTTCCCTCTTTGAGA
TG
GTACAACGCCTTACTTTGGATCACAGACTTAATGATTCCTATTCTTGCCTGGGCTGGTTCAGTCCTGGCCAGGTGTTTGTACTAGACGAGTATTGCGC
CCGAAATGGAGTCCGGGGGTGTCACCGACATCTCTGCTACCTCAGAGACTTGCTTGAACGGGCAGAAAATGGCGCCATGATCGACCCCACCCTTCTTCAC
TACAGCTTTGCCTTCTGTGCATCCCATGTCCATGGGAACAGGCCTGATGGAATTGGAACTGTGACTGTTGAAGAAAAGGAACGTTTTGAAGAAATCAAAG
AGAGGCTCCGAGTTCTGCTAGAAAATCAGATTACACATTTTAGGTATTGCTTTCCATTTGGTCGACCTGAAGGTGCTTTGAAAGCTACTCTCTCACTCTT
GGAAAGGGTTTTGATGAAAGATATTGTTACCCCAGTGCCACAAGAGGAGGTAAAAACAGTTATCCGTAAATGTCTGGAACAGGCTGCGTTAGTCAACTAT
TCTCGGCTCTCAGAGTATGCCAAAATCGAAGGGAAAAAGAGAGAAATGTATGAGCATCCTGTCTTCTGCTTGGCCTCCCAAGTGATGGATTTAACCATTC
AAAATGTAGGCCGGTTAATCACTCCTGCCAAAAAGCTTGAAGATACAATACGTCTTGCTGAACTAGTCATTGAAGTTCTTCAGCAAAATGAGGAGCACCA
CGCAGAGGCCTTTGCGTGGTGGTCAGATTTAATGGTGGAGCATGCGGAGACGTTCCTGTCACTCTTTGCAGTAGACATGGATGCAGCCTTAGAGGTGCAA
CCTCCAGACACATGGGACAGTTTTCCACTATTTCAGCTGCTGAATGATTTTCTCCGTACTGACTATAATTTGTGCAATGGAAAATTTCACAAACACCTGC
AAGACCTGTTTGCCCCACTTGTTGTTAGATATGTGGATCTGATGGAGTCCTCAATTGCACAATCCATTCACAGGGGCTTTGAGCGGGAGTCATGGGAACC
AGTCAATAATGGGTCAGGCACCTCAGAAGATCTGTTTTGGAAACTTGACGCCCTTCAGACCTTCATTCGGGACCTGCACTGGCCTGAAGAAGAGTTTGGA
AAGCACCTGGAACAACGGCTGAAGTTGATGGCAAGTGACATGATCGAATCTTGTGTCAAAAGAACCAGGATTGCATTTGAAGTTAAGCTGCAAAAAACCA
GTCGATCAACAGATTTTCGAGTCCCACAGTCAATATGCACCATGTTTAATGTTATGGTTGATGCCAAAGCTCAATCAACAAAACTTTGCAGCATGGAAAT
GGGCCAAGAGCATCAATACCATTCAAAAATAGACGAACTAATTGAAGAAACTGTTAAAGAAATGATAACACTCTTGGTTGCAAAGTTCGTTACTATCTTG
GAAGGAGTGCTGGCAAAATTATCCAGATATGACGAAGGGACTTTGTTTTCTTCTTTTCTGTCATTTACCGTGAAGGCAGCTTCCAAATATGTGGATGTAC
CTAAACCCGGGATGGACGTGGCCGACGCCTACGTGACTTTCGTCCGCCATTCTCAGGATGTCCTGCGTGATAAGGTCAATGAGGAGATGTACATAGAAAG
GTTATTTGATCAATGGTACAACAGCTCCATGAACGTGATCTGCACCTGGTTGACGGACCGGATGGACTTACAGCTTCATATTTATCAGTTGAAAACACTA
ATTAGGATGGTAAAGAAAACCTACAGAGATTTCCGATTGCAAGGGGTCCTGGACTCCACCTTAAACAGCAAGACCTATGAAACGATCCGGAACCGTCTCA
CTGTGGAGGAAGCCACAGCATCAGTGAGTGAAGGTGGGGGACTGCAGGGCATCAGCATGAAGGACAGCGATGAGGAAGACGAAGAAGACGATTAGACCAT
TTGGTCCTAGAGTCTGCTGGGACAGAGTCCTGTAATCAGTGCATGTCCTTAGTCTGTTAGTTAAACCCATTAGGAATTTTCTGTCAACTACCATGCCCAT
GAGATGTTTATCAATACAACTGCCATTTTAGCTATGTGGTACCAAGATTAGCAAATGACCTTCATATCCACTGATTTCCTGATGTCCATGTCTATATGTT
TACAAGCAATATGGAGCACCATTCTTTAAATACTGTTCATGGAGAATACATAGTCTAACCACTAGGCGTGTCCCTGTTATCAGCAAAGATCAATGATGCT
TCATTCATGTACTATGTATGCATTGGTGGTAAATGGATGTGAGGGCAAGTACATCAAGTACATTCACTCTGTTTCACGTATGTGGATGCCAGTTAATTAA
ATGAGTACGTAAATAAATTAATTAAAACACATAGATCTGCTTTGTGTTTTTATTTTTATTTTTTGAAAAACAAAAGGCAAGTCTCCAACAATTAACTTTT
GATGCTTTCTGTTCCCCTAAAACCAAAAAATGAACCCCTTGTGTCGTTGTTAACCCATCCTTTCATTTACTCATATAATTAGCCAAAAAAAAAAGGATGG
CTACATACCAATGGATTGATTCTCTTAATTGCCACGGCAAGGGGGCGATCCTATCATGACTTAACATCAAGCGCGCAGTTCAAAACTACTGTCTTCTGTC
AAAGTTTTCTCCTCTTAAATGTTATTTTGCTTTTACGTCTCAACTGTGTATGTAAAAAAAATGAATATTTAAATTACAACCCTAGACTAAAAATGTGTTT
ATAATAAGATGTGGATATTTCCTTCAGTAGATTGTAACCATAATTTAAATTATTTTGTTCCACACTGTTTTTTATATCTGTCATGTACATTGCATTTTGA
TCTGTAACTGCACAACCCTGGGGTTTGCTGCAGAGCTATTTCTTTCCATGTAAAGTAGTGGATCCATCTTGCTTTTGCCTTATATAAAGCCTACAGTTAT
GGAAGTGTGGAAAACTGTGGCTTCTCAATAAATATTCAGATGTCCTAAGAATATA
  • refseq_CADPS.F4 (forward primer)
  • refseq_CADPS.R4 (reverse primer)
  • Alternative donor

Frame 0

TACNTRHLFWRRLLQQPQMASGCGLGARN*FSP
LPTSSPRTHLSLPLLPSRFWV*AQLATAGQRISR
GGRG*AAALSLPDLGRSAHPGELIPGCLQRPPP
FALQAGGSRDPAPQAPLCWTLRPAKKNRMRSWR
RRAARRCSARPRPARACLPAVPARARPAAPGWGA
AAPAPEPGWVQAAAGAAARAAAAGPGGCNPAAA
LAAAGPPAPARRW*ARRRRKSWSGCRKRRRRGR
RGCSCMCS*CAASPTPLMPSSPPTWLAGSRRSAN
SSCRQSRTGFRLSSMGKPRSWLTKPS*TLCRVT
MRCS*RATVWPAWFRVEAVPPTTPGRSSRSTLR
RECAACLRLTASARRLC*APGWPNLMPSTVEKRT
RGSSRPG*QPAQPPS*F*ARSNSMRCSRTFLGS
RSSNISSFTMPASWTIQMSKQPRSDESWMDVYK
WQTK*PGNANFPSLYPKKWKTCTLRS*SHLSTCS
WPTWRACRYPKAGSSSSRNSNAATMLPSSTWAR
RVRTSSPSQMSCCLSHWRW*LWKSKASNLWLQI
ASYIAQWRWKEERNYRLIRPRLLNQPGAPRVTSP
QPMHCQL*R*SCSQRAQASWRWRTRSLGGLFSI
PPRTAPNSQSGTK*QSPKTAPTKISKSNLLSEW
ISLKT*SILGIYGPSVRMSGRDGRKGFLYWCRSV
STRLPCAVIGRRKRSLRNFYNWMATLWITPTPS
QVWRVAEPSSMLSRRETP*YLPVTMNKTASCGS
RPCIGPRGSHTSLCPRPKSRNSTPREEMYLSWMP
LSLNFTQIELKNMAWMNLSLPTPVTLTTLPSLR
W
YNALLWITDLMIPILAWAGSVLARCLY*TSIA
PEMESGGVTDISATSETCLNGQKMAP*STPPFFT
TALPSVHPMSMGTGLMELEL*LLKKRNVLKKSK
RGSEFC*KIRLHILGIAFHLVDLKVL*KLLSHS
WKGF**KILLPQCHKRR*KQLSVNVWNRLR*STI
LGSQSMPKSKGKREKCMSILSSAWPPK*WI*PF
KM*AG*SLLPKSLKIQYVLLN*SLKFFSKMRST
TQRPLRGGQI*WWSMRRRSCHSLQ*TWMQP*RCN
LQTHGTVFHYFSC*MIFSVLTIICAMENFTNTC
KTCLPHLLLDMWI*WSPQLHNPFTGALSGSHGN
QSIMGQAPQKICFGNLTPFRPSFGTCTGLKKSLE
STWNNG*S*WQVT*SNLVSKEPGLHLKLSCKKP
VDQQIFESHSQYAPCLMLWLMPKLNQQNFAAWK
WAKSINTIQK*TN*LKKLLKK**HSWLQSSLLSW
KECWQNYPDMTKGLCFLLFCHLP*RQLPNMWMY
LNPGWTWPTPT*LSSAILRMSCVIRSMRRCT*K
GYLINGTTAP*T*SAPG*RTGWTYSFIFIS*KH*
LGW*RKPTEISDCKGSWTPP*TARPMKRSGTVS
LWRKPQHQ*VKVGDCRASA*RTAMRKTKKTIRP
FGPRVCWDRVL*SVHVLSLLVKPIRNFLSTTMPM
RCLSIQLPF*LCGTKISK*PSYPLIS*CPCLYV
YKQYGAPFFKYCSWRIHSLTTRRVPVISKDQ*C
FIHVLCMHWW*MDVRASTSSTFTLFHVCGCQLIK
*VRK*IN*NT*ICFVFLFLFFEKQKASLQQLTF
DAFCSPKTKK*TPCVVVNPSFHLLI*LAKKKRM
ATYQWIDSLNCHGKGAILS*LNIKRAVQNYCLLS
KFSPLKCYFAFTSQLCM*KK*IFKLQP*TKNVF
IIRCGYFLQ*IVTII*IILFHTVFYICHVHCIL
ICNCTTLGFAAELFLSM*SSGSILLLPYIKPTVM
EVWKTVASQ*IFRCPKNI

Frame 1

QLATLGIFSGGASFSSRRWHPAAGSGLAIDSPP
CPPRVHGRTSPFPSSLRASGSEPSSRPPGRGSV
AAAEAEQQRSRSLTWGEAPTRES*SPAASSAPHL
LHSKPGAPETPLPRRHYAGPFVQRRRIG*DRGG
GERQGGARLGPVRRAPVSQPYQRGLGRQRRAGG
RRRRRRSRGGCRRRRGQRREQRRRGRGAATQQPR
WRRPALQPQPVGGEREGEGRVGAAAERGGGEEE
EAAAVCVRDALHRLPL*CQAAHRHGSPAAEDQQ
TAAADSQGPVSGFPQWGNPDHG*RSLHERCAELL
*GVPEERPCGPHGSEWRLFRQRLPGGLQEAH*E
ESAQPA*D*RPQQGDCAELLDGQI*CHLPWRRG
PAEAAGPDDSQRSLRADSEQGATL*DVPEHSWDQ
EVRTSAPLQCLPAGQSR*ASSPDQTRAGWTSTN
GRPNSQGTQISQVCIQRNGKHVH*GAEVICQPA
HGQLGEHAGIQRRGVQAPETQTQPQCFHHRHGRG
E*EPALQVRCRAVFLIGGGNYGSPRPQIFGSKS
HRILHNGGGRRRETTD*SGRGF*TNLGHPG*LL
HNPCTASCEGEAVHREHRRPGVGGQGAWAGYSPS
HPEQPQTVRVAQNDSLQKLPRPRSQNQTCCPNG
*ASKHEAFWVFMGHR*ECLEEMEEKVFCIGAGQ
SVHVCHVQLSGEESGASGTSTIGWLHCGLHRPPA
RFGGWPSLLQCCQGGRHRDICQ*R*TRPHPVGP
GHVSGHGAVTQACAPDPSPETQRQGRKCTSAGC
PYLSILRR*SSKTWHG*IYLFQPL*L*PRFPL*D
GTTPYFGSQT**FLFLPGLVQSWPGVCTRRVLR
PKWSPGVSPTSLLPQRLA*TGRKWRHDRPHPSS
LQLCLLCIPCPWEQA*WNWNCDC*RKGTF*RNQR
EAPSSARKSDYTF*VLLSIWST*RCFESYSLTL
GKGFDERYCYPSATRGGKNSYP*MSGTGCVSQL
FSALRVCQNRREKERNV*ASCLLLGLPSDGFNHS
KCRPVNHSCQKA*RYNTSC*TSH*SSSAK*GAP
RRGLCVVVRFNGGACGDVPVTLCSRHGCSLRGA
TSRHMGQFSTISAAE*FSPY*L*FVQWKISQTPA
RPVCPTCC*ICGSDGVLNCTIHSQGL*AGVMGT
SQ*WVRHLRRSVLET*RPSDLHSGPALA*RRVW
KAPGTTAEVDGK*HDRILCQKNQDCI*S*AAKNQ
SINRFSSPTVNMHHV*CYG*CQSSINKTLQHGN
GPRASIPFKNRRTN*RNC*RNDNTLGCKVRYYL
GRSAGKIIQI*RRDFVFFFSVIYREGSFQICGCT
*TRDGRGRRLRDFRPPFSGCPA**GQ*GDVHRK
VI*SMVQQLHERDLHLVDGPDGLTASYLSVENT
N*DGKENLQRFPIARGPGLHLKQQDL*NDPEPSH
CGGSHSISE*RWGTAGHQHEGQR*GRRRRRLDH
LVLESAGTESCNQCMSLVC*LNPLGIFCQLPCP
*DVYQYNCHFSYVVPRLANDLHIH*FPDVHVYMF
TSNMEHHSLNTVHGEYIV*PLGVSLLSAKINDA
SFMYYVCIGGKWM*GQVHQVHSLCFTYVDAS*L
NEYVNKLIKTHRSALCFYFYFLKNKRQVSNN*LL
MLSVPLKPKNEPLVSLLTHPFIYSYN*PKKKGW
LHTNGLILLIATARGRSYHDLTSSAQFKTTVFC
QSFLLLNVILLLRLNCVCKKNEYLNYNPRLKMCL
**DVDISFSRL*P*FKLFCSTLFFISVMYIAF*
SVTAQPWGLLQSYFFPCKVVDPSCFCLI*SLQL
WKCGKLWLLNKYSDVLRI

Frame 2

SLQHSASFLEAPPSAAADGIRLRARGSQLILPL
AHLESTDAPLPSPPPFALLGLSPARDRRAEDQS
RRPRLSSSALAP*PGEKRPPGRADPRLPPAPPT
FCTPSRGLQRPRSPGATMLDPSSSEEESDEIVEE
ESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGG
GGAGAGAGVGAGGGGGSGASSGGGAGGLQPSSR
AGGGRPSSPSPSVVSEKEKEELERLQKEEEERKK
RLQLYVFVMRCIAYPFNAKQPTDMARRQQKISK
QQLQTVKDRFQAFLNGETQIMADEAFMNAVQSY
YEVFLKSDRVARMVQSGGCSANDSREVFKKHIEK
RVRSLPEIDGLSKETVLSSWMAKFDAIYRGEED
PRKQQARMTASAASELILSKEQLYEMFQNILGI
KKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQM
ADQIARERKFPKFVSKEMENMYIEELKSSVNLL
MANLESMPVSKGGEFKLQKLKRSHNASIIDMGE
ESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNR
IVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFS
TTHALPAVKVKLFTESTGVLALEDKELGRVILH
PTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMD
KPQNMKHSGYLWAIGKNVWKRWKKRFFVLVQVS
QYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQ
PGLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQ
AMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDA
PISQFYADRAQKHGMDEFISSNPCNFDHASLFE
M
VQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCA
RNGVRGCHRHLCYLRDLLERAENGAMIDPTLLH
YSFAFCASHVHGNRPDGIGTVTVEEKERFEEIK
ERLRVLLENQITHFRYCFPFGRPEGALKATLSLL
ERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNY
SRLSEYAKIEGKKREMYEHPVFCLASQVMDLTI
QNVGRLITPAKKLEDTIRLAELVIEVLQQNEEHH
AEAFAWWSDLMVEHAETFLSLFAVDMDAALEVQ
PPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHL
QDLFAPLVVRYVDLMESSIAQSIHRGFERESWEP
VNNGSGTSEDLFWKLDALQTFIRDLHWPEEEFG
KHLEQRLKLMASDMIESCVKRTRIAFEVKLQKT
SRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEM
GQEHQYHSKIDELIEETVKEMITLLVAKFVTIL
EGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDV
PKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIER
LFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTL
IRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRL
TVEEATASVSEGGGLQGISMKDSDEEDEEDD*TI
WS*SLLGQSPVISACP*SVS*TH*EFSVNYHAH
EMFINTTAILAMWYQD*QMTFISTDFLMSMSIC
LQAIWSTIL*ILFMENT*SNH*ACPCYQQRSMML
HSCTMYALVVNGCEGKYIKYIHSVSRMWMPVN*
MST*IN*LKHIDLLCVFIFIF*KTKGKSPTINF
*CFLFP*NQKMNPLCRC*PILSFTHIISQKKKDG
YIPMD*FS*LPRQGGDPIMT*HQARSSKLLSSV
KVFSS*MLFCFYVSTVYVKKMNI*ITTLD*KCV
YNKMWIFPSVDCNHNLNYFVPHCFLYLSCTLHFD
L*LHNPGVCCRAISFHVK*WIHLAFALYKAYSY
GSVENCGFSINIQMS*EY

Sequence NM_003716

ACAGCTTGCAACACTCGGCATCTTTTCTGGAGGCGCCTCCTTCAGCAGCCGCAGATGGCATCCGGCTGCGGGCTCGGGGCTCGCAATTGATTCTCCCCCT
TGCCCACCTCGAGTCCACGGACGCACCTCTCCCTTCCCCTCCTCCCTTCGCGCTTCTGGGTCTGAGCCCAGCTCGCGACCGCCGGGCAGAGGATCAGTCG
CGGCGGCCGAGGCTGAGCAGCAGCGCTCTCGCTCCCTGACCTGGGGAGAAGCGCCCACCCGGGAGAGCTGATCCCCGGCTGCCTCCAGCGCCCCCCACCT
TTTGCACTCCAAGCCGGGGGCTCCAGAGACCCCGCTCCCCAGGCGCCACTATGCTGGACCCTTCGTCCAGCGAAGAAGAATCGGATGAGATCGTGGAGGA
GGAGAGCGGCAAGGAGGTGCTCGGCTCGGCCCCGTCCGGCGCGCGCCTGTCTCCCAGCCGTACCAGCGAGGGCTCGGCCGGCAGCGCCGGGCTGGGGGGC
GGCGGCGCCGGCGCCGGAGCCGGGGTGGGTGCAGGCGGCGGCGGGGGCAGCGGCGCGAGCAGCGGCGGCGGGGCCGGGGGGCTGCAACCCAGCAGCCGCG
CTGGCGGCGGCCGGCCCTCCAGCCCCAGCCCGTCGGTGGTGAGCGAGAAGGAGAAGGAAGAGTTGGAGCGGCTGCAGAAAGAGGAGGAGGAGAGGAAGAA
GAGGCTGCAGCTGTATGTGTTCGTGATGCGCTGCATCGCCTACCCCTTTAATGCCAAGCAGCCCACCGACATGGCTCGCCGGCAGCAGAAGATCAGCAAA
CAGCAGCTGCAGACAGTCAAGGACCGGTTTCAGGCTTTCCTCAATGGGGAAACCCAGATCATGGCTGACGAAGCCTTCATGAACGCTGTGCAGAGTTACT
ATGAGGTGTTCCTGAAGAGCGACCGTGTGGCCCGCATGGTTCAGAGTGGAGGCTGTTCCGCCAACGACTCCCGGGAGGTCTTCAAGAAGCACATTGAGAA
GAGAGTGCGCAGCCTGCCTGAGATTGACGGCCTCAGCAAGGAGACTGTGCTGAGCTCCTGGATGGCCAAATTTGATGCCATCTACCGTGGAGAAGAGGAC
CCGCGGAAGCAGCAGGCCCGGATGACAGCCAGCGCAGCCTCCGAGCTGATTCTGAGCAAGGAGCAACTCTATGAGATGTTCCAGAACATTCTTGGGATCA
AGAAGTTCGAACATCAGCTCCTTTACAATGCCTGCCAGCTGGACAATCCAGATGAGCAAGCAGCCCAGATCAGACGAGAGCTGGATGGACGTCTACAAAT
GGCAGACCAAATAGCCAGGGAACGCAAATTTCCCAAGTTTGTATCCAAAGAAATGGAAAACATGTACATTGAGGAGCTGAAGTCATCTGTCAACCTGCTC
ATGGCCAACTTGGAGAGCATGCCGGTATCCAAAGGCGGGGAGTTCAAGCTCCAGAAACTCAAACGCAGCCACAATGCTTCCATCATCGACATGGGCGAGG
AGAGTGAGAACCAGCTCTCCAAGTCAGATGTCGTGCTGTCTTTCTCATTGGAGGTGGTAATTATGGAAGTCCAAGGCCTCAAATCTTTGGCTCCAAATCG
CATCGTATATTGCACAATGGAGGTGGAAGGAGGAGAGAAACTACAGACTGATCAGGCCGAGGCTTCTAAACCAACCTGGGGCACCCAGGGTGACTTCTCC
ACAACCCATGCACTGCCAGCTGTGAAGGTGAAGCTGTTCACAGAGAGCACAGGCGTCCTGGCGTTGGAGGACAAGGAGCTTGGGCGGGTTATTCTCCATC
CCACCCCGAACAGCCCCAAACAGTCAGAGTGGCACAAAATGACAGTCTCCAAAAACTGCCCCGACCAAGATCTCAAAATCAAACTTGCTGTCCGAATGGA
TAAGCCTCAAAACATGAAGCATTCTGGGTATTTATGGGCCATCGGTAAGAATGTCTGGAAGAGATGGAAGAAAAGGTTTTTTGTATTGGTGCAGGTCAGT
CAGTACACGTTTGCCATGTGCAGTTATCGGGAGAAGAAAGCGGAGCCTCAGGAACTTCTACAATTGGATGGCTACACTGTGGATTACACCGACCCCCAGC
CAGGTTTGGAGGGTGGCCGAGCCTTCTTCAATGCTGTCAAGGAGGGAGACACCGTGATATTTGCCAGTGACGATGAACAAGACCGCATCCTGTGGGTCCA
GGCCATGTATCGGGCCACGGGGCAGTCACACAAGCCTGTGCCCCCGACCCAAGTCCAGAAACTCAACGCCAAGGGAGGAAATGTACCTCAGCTGGATGCC
CCTATCTCTCAATTTTACGCAGATAGAGCTCAAAAACATGGCATGGATGAATTTATCTCTTCCAACCCCTGTAACTTTGACCACGCTTCCCTCTTTGAGA
TG
GTACAACGCCTTACTTTGGATCACAGACTTAATGATTCCTATTCTTGCCTGGGCTGGTTCAGTCCTGGCCAGGTGTTTGTACTAGACGAGTATTGCGC
CCGAAATGGAGTCCGGGGGTGTCACCGACATCTCTGCTACCTCAGAGACTTGCTTGAACGGGCAGAAAATGGCGCCATGATCGACCCCACCCTTCTTCAC
TACAGCTTTGCCTTCTGTGCATCCCATGTCCATGGGAACAGGCCTGATGGAATTGGAACTGTGACTGTTGAAGAAAAGGAACGTTTTGAAGAAATCAAAG
AGAGGCTCCGAGTTCTGCTAGAAAATCAGATTACACATTTTAGGTATTGCTTTCCATTTGGTCGACCTGAAGGTGCTTTGAAAGCTACTCTCTCACTCTT
GGAAAGGGTTTTGATGAAAGATATTGTTACCCCAGTGCCACAAGAGGAGGTAAAAACAGTTATCCGTAAATGTCTGGAACAGGCTGCGTTAGTCAACTAT
TCTCGGCTCTCAGAGTATGCCAAAATCGAAGAGAATCAAAAGGATGCAGAAAATGTAGGCCGGTTAATCACTCCTGCCAAAAAGCTTGAAGATACAATAC
GTCTTGCTGAACTAGTCATTGAAGTTCTTCAGCAAAATGAGGAGCACCACGCAGAGCCACATGTTGATAAAGGAGAAGCCTTTGCGTGGTGGTCAGATTT
AATGGTGGAGCATGCGGAGACGTTCCTGTCACTCTTTGCAGTAGACATGGATGCAGCCTTAGAGGTGCAACCTCCAGACACATGGGACAGTTTTCCACTA
TTTCAGCTGCTGAATGATTTTCTCCGTACTGACTATAATTTGTGCAATGGAAAATTTCACAAACACCTGCAAGACCTGTTTGCCCCACTTGTTGTTAGAT
ATGTGGATCTGATGGAGTCCTCAATTGCACAATCCATTCACAGGGGCTTTGAGCGGGAGTCATGGGAACCAGTCAAGAGTTTAACCAGTAACCTACCCAA
TGTGAACCTACCCAATGTGAACCTTCCCAAAGTACCAAATCTACCAGTTAACATCCCTCTAGGCATCCCACAAATGCCTACTTTTTCGGCACCGTCATGG
ATGGCTGCTATATATGATGCGGATAATGGGTCAGGCACCTCAGAAGATCTGTTTTGGAAACTTGACGCCCTTCAGACCTTCATTCGGGACCTGCACTGGC
CTGAAGAAGAGTTTGGAAAGCACCTGGAACAACGGCTGAAGTTGATGGCAAGTGACATGATCGAATCTTGTGTCAAAAGAACCAGGATTGCATTTGAAGT
TAAGCTGCAAAAAACCAGTCGATCAACAGATTTTCGAGTCCCACAGTCAATATGCACCATGTTTAATGTTATGGTTGATGCCAAAGCTCAATCAACAAAA
CTTTGCAGCATGGAAATGGGCCAAGAGCATCAATACCATTCAAAAATAGACGAACTAATTGAAGAAACTGTTAAAGAAATGATAACACTCTTGGTTGCAA
AGTTCGTTACTATCTTGGAAGGAGTGCTGGCAAAATTATCCAGATATGACGAAGGGACTTTGTTTTCTTCTTTTCTGTCATTTACCGTGAAGGCAGCTTC
CAAATATGTGGATGTACCTAAACCCGGGATGGACGTGGCCGACGCCTACGTGACTTTCGTCCGCCATTCTCAGGATGTCCTGCGTGATAAGGTCAATGAG
GAGATGTACATAGAAAGGTTATTTGATCAATGGTACAACAGCTCCATGAACGTGATCTGCACCTGGTTGACGGACCGGATGGACTTACAGCTTCATATTT
ATCAGTTGAAAACACTAATTAGGATGGTAAAGAAAACCTACAGAGATTTCCGATTGCAAGGGGTCCTGGACTCCACCTTAAACAGCAAGACCTATGAAAC
GATCCGGAACCGTCTCACTGTGGAGGAAGCCACAGCATCAGTGAGTGAAGGTGGGGGACTGCAGGGCATCAGCATGAAGGACAGCGATGAGGAAGACGAA
GAAGACGATTAGACCATTTGGTCCTAGAGTCTGCTGGGACAGAGTCCTGTAATCAGTGCATGTCCTTAGTCTGTTAGTTAAACCCATTAGGAATTTTCTG
TCAACTACCATGCCCATGAGATGTTTATCAATACAACTGCCATTTTAGCTATGTGGTACCAAGATTAGCAAATGACCTTCATATCCACTGATTTCCTGAT
GTCCATGTCTATATGTTTACAAGCAATATGGAGCACCATTCTTTAAATACTGTTCATGGAGAATACATAGTCTAACCACTAGGCGTGTCCCTGTTATCAG
CAAAGATCAATGATGCTTCATTCATGTACTATGTATGCATTGGTGGTAAATGGATGTGAGGGCAAGTACATCAAGTACATTCACTCTGTTTCACGTATGT
GGATGCCAGTTAATTAAATGAGTACGTAAATAAATTAATTAAAACACATAGATCTGCTTTGTGTTTTTATTTTTATTTTTTGAAAAACAAAAGGCAAGTC
TCCAACAATTAACTTTTGATGCTTTCTGTTCCCCTAAAACCAAAAAATGAACCCCTTGTGTCGTTGTTAACCCATCCTTTCATTTACTCATATAATTAGC
CAAAAAAAAAAGGATGGCTACATACCAATGGATTGATTCTCTTAATTGCCACGGCAAGGGGGCGATCCTATCATGACTTAACATCAAGCGCGCAGTTCAA
AACTACTGTCTTCTGTCAAAGTTTTCTCCTCTTAAATGTTATTTTGCTTTTACGTCTCAACTGTGTATGTAAAAAAAATGAATATTTAAATTACAACCCT
AGACTAAAAATGTGTTTATAATAAGATGTGGATATTTCCTTCAGTAGATTGTAACCATAATTTAAATTATTTTGTTCCACACTGTTTTTTATATCTGTCA
TGTACATTGCATTTTGATCTGTAACTGCACAACCCTGGGGTTTGCTGCAGAGCTATTTCTTTCCATGTAAAGTAGTGGATCCATCTTGCTTTTGCCTTAT
ATAAAGCCTACAGTTATGGAAGTGTGGAAAACTGTGGCTTCTCAATAAATATTCAGATGTCCTAAGAATATA
  • refseq_CADPS.F4 (forward primer)
  • refseq_CADPS.R4 (reverse primer)
  • Alternative donor

Frame 0

TACNTRHLFWRRLLQQPQMASGCGLGARN*FSP
LPTSSPRTHLSLPLLPSRFWV*AQLATAGQRISR
GGRG*AAALSLPDLGRSAHPGELIPGCLQRPPP
FALQAGGSRDPAPQAPLCWTLRPAKKNRMRSWR
RRAARRCSARPRPARACLPAVPARARPAAPGWGA
AAPAPEPGWVQAAAGAAARAAAAGPGGCNPAAA
LAAAGPPAPARRW*ARRRRKSWSGCRKRRRRGR
RGCSCMCS*CAASPTPLMPSSPPTWLAGSRRSAN
SSCRQSRTGFRLSSMGKPRSWLTKPS*TLCRVT
MRCS*RATVWPAWFRVEAVPPTTPGRSSRSTLR
RECAACLRLTASARRLC*APGWPNLMPSTVEKRT
RGSSRPG*QPAQPPS*F*ARSNSMRCSRTFLGS
RSSNISSFTMPASWTIQMSKQPRSDESWMDVYK
WQTK*PGNANFPSLYPKKWKTCTLRS*SHLSTCS
WPTWRACRYPKAGSSSSRNSNAATMLPSSTWAR
RVRTSSPSQMSCCLSHWRW*LWKSKASNLWLQI
ASYIAQWRWKEERNYRLIRPRLLNQPGAPRVTSP
QPMHCQL*R*SCSQRAQASWRWRTRSLGGLFSI
PPRTAPNSQSGTK*QSPKTAPTKISKSNLLSEW
ISLKT*SILGIYGPSVRMSGRDGRKGFLYWCRSV
STRLPCAVIGRRKRSLRNFYNWMATLWITPTPS
QVWRVAEPSSMLSRRETP*YLPVTMNKTASCGS
RPCIGPRGSHTSLCPRPKSRNSTPREEMYLSWMP
LSLNFTQIELKNMAWMNLSLPTPVTLTTLPSLR
W
YNALLWITDLMIPILAWAGSVLARCLY*TSIA
PEMESGGVTDISATSETCLNGQKMAP*STPPFFT
TALPSVHPMSMGTGLMELEL*LLKKRNVLKKSK
RGSEFC*KIRLHILGIAFHLVDLKVL*KLLSHS
WKGF**KILLPQCHKRR*KQLSVNVWNRLR*STI
LGSQSMPKSKRIKRMQKM*AG*SLLPKSLKIQY
VLLN*SLKFFSKMRSTTQSHMLIKEKPLRGGQI
*WWSMRRRSCHSLQ*TWMQP*RCNLQTHGTVFHY
FSC*MIFSVLTIICAMENFTNTCKTCLPHLLLD
MWI*WSPQLHNPFTGALSGSHGNQSRV*PVTYP
M*TYPM*TFPKYQIYQLTSL*ASHKCLLFRHRHG
WLLYMMRIMGQAPQKICFGNLTPFRPSFGTCTG
LKKSLESTWNNG*S*WQVT*SNLVSKEPGLHLK
LSCKKPVDQQIFESHSQYAPCLMLWLMPKLNQQN
FAAWKWAKSINTIQK*TN*LKKLLKK**HSWLQ
SSLLSWKECWQNYPDMTKGLCFLLFCHLP*RQL
PNMWMYLNPGWTWPTPT*LSSAILRMSCVIRSMR
RCT*KGYLINGTTAP*T*SAPG*RTGWTYSFIF
IS*KH*LGW*RKPTEISDCKGSWTPP*TARPMK
RSGTVSLWRKPQHQ*VKVGDCRASA*RTAMRKTK
KTIRPFGPRVCWDRVL*SVHVLSLLVKPIRNFL
STTMPMRCLSIQLPF*LCGTKISK*PSYPLIS*
CPCLYVYKQYGAPFFKYCSWRIHSLTTRRVPVIS
KDQ*CFIHVLCMHWW*MDVRASTSSTFTLFHVC
GCQLIK*VRK*IN*NT*ICFVFLFLFFEKQKAS
LQQLTFDAFCSPKTKK*TPCVVVNPSFHLLI*LA
KKKRMATYQWIDSLNCHGKGAILS*LNIKRAVQ
NYCLLSKFSPLKCYFAFTSQLCM*KK*IFKLQP
*TKNVFIIRCGYFLQ*IVTII*IILFHTVFYICH
VHCILICNCTTLGFAAELFLSM*SSGSILLLPY
IKPTVMEVWKTVASQ*IFRCPKNI

Frame 1

QLATLGIFSGGASFSSRRWHPAAGSGLAIDSPP
CPPRVHGRTSPFPSSLRASGSEPSSRPPGRGSV
AAAEAEQQRSRSLTWGEAPTRES*SPAASSAPHL
LHSKPGAPETPLPRRHYAGPFVQRRRIG*DRGG
GERQGGARLGPVRRAPVSQPYQRGLGRQRRAGG
RRRRRRSRGGCRRRRGQRREQRRRGRGAATQQPR
WRRPALQPQPVGGEREGEGRVGAAAERGGGEEE
EAAAVCVRDALHRLPL*CQAAHRHGSPAAEDQQ
TAAADSQGPVSGFPQWGNPDHG*RSLHERCAELL
*GVPEERPCGPHGSEWRLFRQRLPGGLQEAH*E
ESAQPA*D*RPQQGDCAELLDGQI*CHLPWRRG
PAEAAGPDDSQRSLRADSEQGATL*DVPEHSWDQ
EVRTSAPLQCLPAGQSR*ASSPDQTRAGWTSTN
GRPNSQGTQISQVCIQRNGKHVH*GAEVICQPA
HGQLGEHAGIQRRGVQAPETQTQPQCFHHRHGRG
E*EPALQVRCRAVFLIGGGNYGSPRPQIFGSKS
HRILHNGGGRRRETTD*SGRGF*TNLGHPG*LL
HNPCTASCEGEAVHREHRRPGVGGQGAWAGYSPS
HPEQPQTVRVAQNDSLQKLPRPRSQNQTCCPNG
*ASKHEAFWVFMGHR*ECLEEMEEKVFCIGAGQ
SVHVCHVQLSGEESGASGTSTIGWLHCGLHRPPA
RFGGWPSLLQCCQGGRHRDICQ*R*TRPHPVGP
GHVSGHGAVTQACAPDPSPETQRQGRKCTSAGC
PYLSILRR*SSKTWHG*IYLFQPL*L*PRFPL*D
GTTPYFGSQT**FLFLPGLVQSWPGVCTRRVLR
PKWSPGVSPTSLLPQRLA*TGRKWRHDRPHPSS
LQLCLLCIPCPWEQA*WNWNCDC*RKGTF*RNQR
EAPSSARKSDYTF*VLLSIWST*RCFESYSLTL
GKGFDERYCYPSATRGGKNSYP*MSGTGCVSQL
FSALRVCQNRRESKGCRKCRPVNHSCQKA*RYNT
SC*TSH*SSSAK*GAPRRATC**RRSLCVVVRF
NGGACGDVPVTLCSRHGCSLRGATSRHMGQFST
ISAAE*FSPY*L*FVQWKISQTPARPVCPTCC*I
CGSDGVLNCTIHSQGL*AGVMGTSQEFNQ*PTQ
CEPTQCEPSQSTKSTS*HPSRHPTNAYFFGTVM
DGCYI*CG*WVRHLRRSVLET*RPSDLHSGPALA
*RRVWKAPGTTAEVDGK*HDRILCQKNQDCI*S
*AAKNQSINRFSSPTVNMHHV*CYG*CQSSINK
TLQHGNGPRASIPFKNRRTN*RNC*RNDNTLGCK
VRYYLGRSAGKIIQI*RRDFVFFFSVIYREGSF
QICGCT*TRDGRGRRLRDFRPPFSGCPA**GQ*
GDVHRKVI*SMVQQLHERDLHLVDGPDGLTASYL
SVENTN*DGKENLQRFPIARGPGLHLKQQDL*N
DPEPSHCGGSHSISE*RWGTAGHQHEGQR*GRR
RRRLDHLVLESAGTESCNQCMSLVC*LNPLGIFC
QLPCP*DVYQYNCHFSYVVPRLANDLHIH*FPD
VHVYMFTSNMEHHSLNTVHGEYIV*PLGVSLLS
AKINDASFMYYVCIGGKWM*GQVHQVHSLCFTYV
DAS*LNEYVNKLIKTHRSALCFYFYFLKNKRQV
SNN*LLMLSVPLKPKNEPLVSLLTHPFIYSYN*
PKKKGWLHTNGLILLIATARGRSYHDLTSSAQFK
TTVFCQSFLLLNVILLLRLNCVCKKNEYLNYNP
RLKMCL**DVDISFSRL*P*FKLFCSTLFFISV
MYIAF*SVTAQPWGLLQSYFFPCKVVDPSCFCLI
*SLQLWKCGKLWLLNKYSDVLRI

Frame 2

SLQHSASFLEAPPSAAADGIRLRARGSQLILPL
AHLESTDAPLPSPPPFALLGLSPARDRRAEDQS
RRPRLSSSALAP*PGEKRPPGRADPRLPPAPPT
FCTPSRGLQRPRSPGATMLDPSSSEEESDEIVEE
ESGKEVLGSAPSGARLSPSRTSEGSAGSAGLGG
GGAGAGAGVGAGGGGGSGASSGGGAGGLQPSSR
AGGGRPSSPSPSVVSEKEKEELERLQKEEEERKK
RLQLYVFVMRCIAYPFNAKQPTDMARRQQKISK
QQLQTVKDRFQAFLNGETQIMADEAFMNAVQSY
YEVFLKSDRVARMVQSGGCSANDSREVFKKHIEK
RVRSLPEIDGLSKETVLSSWMAKFDAIYRGEED
PRKQQARMTASAASELILSKEQLYEMFQNILGI
KKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQM
ADQIARERKFPKFVSKEMENMYIEELKSSVNLL
MANLESMPVSKGGEFKLQKLKRSHNASIIDMGE
ESENQLSKSDVVLSFSLEVVIMEVQGLKSLAPNR
IVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFS
TTHALPAVKVKLFTESTGVLALEDKELGRVILH
PTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMD
KPQNMKHSGYLWAIGKNVWKRWKKRFFVLVQVS
QYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQ
PGLEGGRAFFNAVKEGDTVIFASDDEQDRILWVQ
AMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDA
PISQFYADRAQKHGMDEFISSNPCNFDHASLFE
M
VQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCA
RNGVRGCHRHLCYLRDLLERAENGAMIDPTLLH
YSFAFCASHVHGNRPDGIGTVTVEEKERFEEIK
ERLRVLLENQITHFRYCFPFGRPEGALKATLSLL
ERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNY
SRLSEYAKIEENQKDAENVGRLITPAKKLEDTI
RLAELVIEVLQQNEEHHAEPHVDKGEAFAWWSDL
MVEHAETFLSLFAVDMDAALEVQPPDTWDSFPL
FQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVR
YVDLMESSIAQSIHRGFERESWEPVKSLTSNLPN
VNLPNVNLPKVPNLPVNIPLGIPQMPTFSAPSW
MAAIYDADNGSGTSEDLFWKLDALQTFIRDLHW
PEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEV
KLQKTSRSTDFRVPQSICTMFNVMVDAKAQSTK
LCSMEMGQEHQYHSKIDELIEETVKEMITLLVA
KFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAAS
KYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNE
EMYIERLFDQWYNSSMNVICTWLTDRMDLQLHI
YQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYET
IRNRLTVEEATASVSEGGGLQGISMKDSDEEDE
EDD*TIWS*SLLGQSPVISACP*SVS*TH*EFS
VNYHAHEMFINTTAILAMWYQD*QMTFISTDFLM
SMSICLQAIWSTIL*ILFMENT*SNH*ACPCYQ
QRSMMLHSCTMYALVVNGCEGKYIKYIHSVSRM
WMPVN*MST*IN*LKHIDLLCVFIFIF*KTKGKS
PTINF*CFLFP*NQKMNPLCRC*PILSFTHIIS
QKKKDGYIPMD*FS*LPRQGGDPIMT*HQARSS
KLLSSVKVFSS*MLFCFYVSTVYVKKMNI*ITTL
D*KCVYNKMWIFPSVDCNHNLNYFVPHCFLYLS
CTLHFDL*LHNPGVCCRAISFHVK*WIHLAFAL
YKAYSYGSVENCGFSINIQMS*EY

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