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Sequences

Sequence NM_139199

GGGTTTCGGCCCTTCCAGACCGTCTCTCCTCAGGGTTGGAGACTTCGGGGCCAAGATGGCGACGGGAACGGGCAAACACAAGCTGCTAAGCACTGGCCCC
ACAGAGCCATGGTCCATCCGAGAGAAGCTATGTTTAGCATCTTCTGTCATGAGAAGTGGCGATCAAAATTGGGTATCAGTTAGCAGAGCAATCAAGCCCT
TTGCAGAACCTGGCCGCCCTCCAGACTGGTTCTCTCAAAAACATTGTGCTTCCCAGTACTCGGAGCTTTTAGAGACCACTGAGACACCAAAACGGAAACG
AGGTGAAAAGGGAGAAGTGGTGGAAACTGTTGAAGATGTTATTGTTCGGAAATTGACTGCTGAGCGAGTTGAAGAACTAAAGAAAGTGATAAAGGAAACC
CAGGAGAGATATAGACGGCTAAAGAGAGATGCAGAACTAATTCAAGCTGGACACATGGACAGCAGACTGGATGAGCTTTGCAATGACATTGCAACGAAAA
AGAAATTGGAAGAAGAGGAGGCTGAAGTAAAGAGGAAGGCTACAGATGCTGCATACCAGGCTCGTCAAGCAGTAAAAACACCCCCCCGGAGGTTACCCAC
TGTGATGGTTCGCTCTCCTATAGATTCTGCCTCCCCAGGAGGTGATTATCCACTTGGGGACTTGACTCCAACCACTATGGAAGAGGCTACCTCTGGGGTC
AATGAGAGTGAAATGGCTGTGGCTTCTGGCCACCTGAACAGTACAGGTGTCCTCCTGGAGGTAGGCGGGGTCCTTCCCATGATACATGGTGGGGAGATAC
AGCAAACACCCAATACTGTTGCAGCCTCCCCTGCTGCATCAGGTGCTCCCACTCTTTCCCGGCTTTTAGAAGCTGGTCCTACACAGTTCACCACACCTCT
TGCTTCCTTCACTACTGTTGCCAGTGAGCCTCCAGTTAAACTTGTGCCACCCCCTGTAGAGTCTGTGTCCCAAGCTACCATTGTCATGATGCCTGCGCTG
CCAGCACCATCCTCTGCTCCGGCTGTCTCCACTACTGAAAGTGTAGCTCCAGTGAGTCAACCCGACAACTGTGTTCCCATGGAGGCTGTGGGGGATCCAC
ATACTGTGACTGTTTCCATGGACAGCAGTGAAATATCCATGATCATCAATTCTATCAAAGAAGAGTGTTTTCGATCAGGGGTAGCAGAGGCTCCTGTTGG
ATCAAAGGCTCCCAGCATAGATGGGAAGGAAGAATTAGATCTGGCTGAGAAGATGGATATTGCTGTGTCTTACACAGGTGAAGAGCTGGATTTTGAGACT
GTTGGAGACATCATTGCCATCATTGAGGACAAGGTAGATGATCATCCTGAAGTGCTGGATGTGGCAGCAGTGGAAGCAGCACTGTCATTTTGTGAAGAAA
ATGATGATCCTCAGTCCCTGCCTGGCCCCTGGGAGCATCCTATCCAGCAGGAGCGGGACAAGCCAGTACCTCTCCCTGCACCAGAAATGACGGTCAAGCA
AGAGAGACTGGACTTTGAGGAAACGGAAAACAAGGGAATACATGAACTGGTGGACATCAGGGAGCCCAGTGCAGAGATCAAGGTGGAACCTGCAGAACCA
GAGCCAGTCATTTCAGGAGCCGAAATAGTAGCTGGAGTTGTTCCAGCCACAAGTATGGAGCCACCAGAACTCAGGAGTCAGGACTTAGATGAGGAACTGG
GAAGTACTGCAGCTGGAGAGATTGTTGAAGCAGATGTTGCCATTGGGAAAGGCGATGAGACTCCACTTACAAATGTGAAGACAGAGGCATCCCCTGAAAG
CATGTTGTCTCCATCACATGGCTCAAATCCCATTGAAGATCCTTTAGAGGCAGAGACTCAGCACAAGTTTGAAATGTCAGACTCATTGAAAGAAGAATCA
GGGACTATTTTTGGAAGCCAGATAAAGGATGCCCCAGGTGAGGATGAGGAGGAAGATGGTGTCAGTGAAGCGGCCAGCCTAGAGGAGCCTAAGGAAGAGG
ATCAAGGAGAAGGCTACTTGTCAGAAATGGATAATGAACCTCCTGTGAGCGAGAGTGATGATGGCTTCAGCATACACAATGCTACACTGCAGTCACACAC
ACTGGCAGACTCCATCCCCAGCAGCCCTGCTTCTTCACAGTTCTCTGTCTGTAGTGAGGATCAGGAAGCTATTCAGGCACAGAAAATTTGGAAGAAAGCC
ATCATGCTTGTATGGAGAGCTGCAGCTAATCATAGGTATGCCAATGTCTTCCTGCAGCCTGTTACAGATGACATAGCACCTGGCTACCACAGCATTGTGC
AGAGGCCTATGGATTTGTCAACTATTAAGAAAAACATAGAAAATGGACTGATCCGAAGCACAGCTGAATTTCAGCGTGACATTATGCTGATGTTTCAGAA
TGCTGTAATGTACAATAGCTCAGACCATGATGTCTATCACATGGCAGTGGAGATGCAGCGAGATGTCTTGGAACAGATCCAGCAATTCTTGGCCACGCAG
TTGATTATGCAAACATCCGAGTCTGGGATCAGTGCTAAAAGTCTTCGAGGGAGAGATTCTACCCGCAAACAGGATGCTTCAGAGAAGGACAGTGTCCCAA
TGGGCTCTCCTGCCTTCCTTCTCTCTCTCTTTATGGGACACGAGTGGGTTTGGCTGGATTCTGAACAAGATCATCCCAATGACTCTGAGTTGAGCAATGA
CTGCAGGTCCCTCTTCAGCTCATGGGACTCCAGTCTGGATCTTGATGTGGGCAACTGGAGGGAAACTGAGGATCCAGAGGCTGAGGAACTAGAGGAAAGC
AGCCCGGAGAGAGAACCTAGTGAACTGCTTGTTGGGGATGGAGGCAGTGAGGAATCTCAGGAAGCGGCAAGGAAAGCCAGCCACCAGAACCTCCTCCACT
TTCTCTCTGAGGTAGCTTATTTAATGGAGCCCTTGTGCATCAGCAGCAACGAATCAAGTGAAGGCTGCTGCCCTCCATCTGGTACCAGACAAGAAGGAAG
GGAAATTAAAGCTAGCGAAGGAGAAAGGGAGCTCTGCAGAGAGACTGAAGAGCTTTCAGCTAAAGGAGACCCCTTAGTAGCTGAAAAGCCACTGGGAGAA
AATGGAAAGCCAGAGGTGGCTTCAGCTCCCTCAGTTATTTGTACAGTTCAGGGACTACTCACAGAGAGTGAAGAGGGGGAGGCTCAGCAAGAATCCAAAG
GGGAGGACCAGGGTGAAGTATATGTGTCAGAGATGGAAGACCAGCCCCCTTCAGGCGAGTGTGATGATGCCTTTAACATTAAGGAGACTCCCTTGGTGGA
TACACTTTTCAGCCATGCTACCTCCTCAAAGCTGACTGATCTAAGCCAGGATGACCCTGTTCAGGATCATTTGCTATTTAAGAAGACTCTCCTGCCAGTC
TGGAAGATGATTGCCAGTCACAGGTTCAGCAGTCCATTTCTGAAGCCTGTGTCAGAAAGGCAGGCCCCAGGGTACAAGGATGTGGTGAAAAGACCCATGG
ACTTAACTAGCCTGAAGAGAAATCTCTCTAAGGGTCGGATTCGCACCATGGCCCAATTCCTGCGAGACCTGATGCTGATGTTCCAAAATGCTGTAATGTA
CAATGACTCTGATCATCATGTATACCATATGGCTGTGGAGATGCGGCAAGAAGTCCTGGAGCAGATTCAGGTACTGAATATCTGGTTAGACAAAAGAAAA
GGCTCAAGTAGTCTGGAAGGAGAACCAGCTAACCCAGTGGATGATGGAAAACCTGTTTTCTAACCTGGAGCTGCTATCCTGACTTTTTCTAGAGTTTGAA
TCTCTCCCGGAACTCTGACCTAGAGAGGATCCTGGTACTTCTTTGCCATGTCCTCATTTTCTTTTCCAACAAGAATAATACCTTAACTCACAACCAACGA
GTCAAAGATGCATGTGGACATAATATAAAGAAAAAAAGGGGAAGCTGAGGTTTGGATTTATGCCATAAATGTTGCCCACATCTTTGTTCCATCGGCTTGA
TTTAAAGACAATTCCATTAGATCTTTTCTAAGCCTTTTACTCTATAAATAAATGTATTTACACAATA
  • refseq_BRD8.F4 (forward primer)
  • refseq_BRD8.R4 (reverse primer)
  • Single exon skipping

Frame 0

GFRPFQTVSPQGWRLRGQDGDGNGQTQAAKHWP
HRAMVHPREAMFSIFCHEKWRSKLGIS*QSNQAL
CRTWPPSRLVLSKTLCFPVLGAFRDH*DTKTET
R*KGRSGGNC*RCYCSEIDC*AS*RTKESDKGN
PGEI*TAKERCRTNSSWTHGQQTG*ALQ*HCNEK
EIGRRGG*SKEEGYRCCIPGSSSSKNTPPEVTH
CDGSLSYRFCLPRR*LSTWGLDSNHYGRGYLWG
Q*E*NGCGFWPPEQYRCPPGGRRGPSHDTWWGDT
ANTQYCCSLPCCIRCSHSFPAFRSWSYTVHHTS
CFLHYCCQ*ASS*TCATPCRVCVPSYHCHDACA
ASTILCSGCLHY*KCSSSESTRQLCSHGGCGGST
YCDCFHGQQ*NIHDHQFYQRRVFSIRGSRGSCW
IKGSQHRWEGRIRSG*EDGYCCVLHR*RAGF*D
CWRHHCHH*GQGR*SS*SAGCGSSGSSTVIL*RK
**SSVPAWPLGASYPAGAGQASTSPCTRNDGQA
RETGL*GNGKQGNT*TGGHQGAQCRDQGGTCRT
RASHFRSRNSSWSCSSHKYGATRTQESGLR*GTG
KYCSWRDC*SRCCHWERR*DSTYKCEDRGIP*K
HVVSITWLKSH*RSFRGRDSAQV*NVRLIERRI
RDYFWKPDKGCPR*G*GGRWCQ*SGQPRGA*GRG
SRRRLLVRNG**TSCERE**WLQHTQCYTAVTH
TGRLHPQQPCFFTVLCL**GSGSYSGTENLEES
HHACMESCS*S*VCQCLPAACYR*HSTWLPQHCA
EAYGFVNY*EKHRKWTDPKHS*ISA*HYADVSE
CCNVQ*LRP*CLSHGSGDAARCLGTDPAILGHA
VDYANIRVWDQC*KSSRERFYPQTGCFREGQCPN
GLSCLPSLSLYGTRVGLAGF*TRSSQ*L*VEQ*
LQVPLQLMGLQSGS*CGQLEGN*GSRG*GTRGK
QPGERT**TACWGWRQ*GISGSGKESQPPEPPPL
SL*GSLFNGALVHQQQRIK*RLLPSIWYQTRRK
GN*S*RRRKGALQRD*RAFS*RRPLSS*KATGR
KWKARGGFSSLSYLYSSGTTHRE*RGGGSARIQR
GGPG*SICVRDGRPAPFRRV**CL*H*GDSLGG
YTFQPCYLLKAD*SKPG*PCSGSFAI*EDSPAS
LEDDCQSQVQQSISEACVRKAGPRVQGCGEKTHG
LN*PEEKSL*GSDSHHGPIPARPDADVPKCCNV
Q*L*SSCIPYGCGDAARSPGADSGTEYLVRQKK
RLK*SGRRTS*PSG*WKTCFLTWSCYPDFF*SLN
LSRNSDLERILVLLCHVLIFFSNKNNTLTHNQR
VKDACGHNIKKKRGS*GLDLCHKCCPHLCSIGL
I*RQFH*IFSKPFTL*INVFTQ

Frame 1

GFGPSRPSLLRVGDFGAKMATGTGKHKLLSTGP
TEPWSIREKLCLASSVMRSGDQNWVSVSRAIKP
FAEPGRPPDWFSQKHCASQYSELLETTETPKRKR
GEKGEVVETVEDVIVRKLTAERVEELKKVIKET
QERYRRLKRDAELIQAGHMDSRLDELCNDIATK
KKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPT
VMVRSPIDSASPGGDYPLGDLTPTTMEEATSGV
NESEMAVASGHLNSTGVLLEVGGVLPMIHGGEI
QQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPL
ASFTTVASEPPVKLVPPPVESVSQATIVMMPAL
PAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDP
HTVTVSMDSSEISMIINSIKEECFRSGVAEAPVG
SKAPSIDGKEELDLAEKMDIAVSYTGEELDFET
VGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEE
NDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQ
ERLDFEETENKGIHELVDIREPSAEIKVEPAEP
EPVISGAEIVAGVVPATSMEPPELRSQDLDEEL
GSTAAGEIVEADVAIGKGDETPLTNVKTEASPES
MLSPSHGSNPIEDPLEAETQHKFEMSDSLKEES
GTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEE
DQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHT
LADSIPSSPASSQFSVCSEDQEAIQAQKIWKKA
IMLVWRAAANHRYANVFLQPVTDDIAPGYHSIV
QRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQN
AVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQ
LIMQTSESGISAKSLRGRDSTRKQDASEKDSVP
MGSPAFLLSLFMGHEWVWLDSEQDHPNDSELSND
CRSLFSSWDSSLDLDVGNWRETEDPEAEELEES
SPEREPSELLVGDGGSEESQEAARKASHQNLLH
FLSEVAYLMEPLCISSNESSEGCCPPSGTRQEGR
EIKASEGERELCRETEELSAKGDPLVAEKPLGE
NGKPEVASAPSVICTVQGLLTESEEGEAQQESK
GEDQGEVYVSEMEDQPPSGECDDAFNIKETPLVD
TLFSHATSSKLTDLSQDDPVQDHLLFKKTLLPV
WKMIASHRFSSPFLKPVSERQAPGYKDVVKRPM
DLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMY
NDSDHHVYHMAVEMRQEVLEQIQVLNIWLDKRK
GSSSLEGEPANPVDDGKPVF*PGAAILTFSRV*
ISPGTLT*RGSWYFFAMSSFSFPTRIIP*LTTNE
SKMHVDII*RKKGEAEVWIYAINVAHIFVPSA*
FKDNSIRSFLSLLLYK*MYLHN

Frame 2

VSALPDRLSSGLETSGPRWRRERANTSC*ALAP
QSHGPSERSYV*HLLS*EVAIKIGYQLAEQSSP
LQNLAALQTGSLKNIVLPSTRSF*RPLRHQNGN
EVKREKWWKLLKMLLFGN*LLSELKN*RK**RKP
RRDIDG*REMQN*FKLDTWTADWMSFAMTLQRK
RNWKKRRLK*RGRLQMLHTRLVKQ*KHPPGGYP
L*WFALL*ILPPQEVIIHLGT*LQPLWKRLPLGS
MRVKWLWLLAT*TVQVSSWR*AGSFP*YMVGRY
SKHPILLQPPLLHQVLPLFPGF*KLVLHSSPHL
LLPSLLLPVSLQLNLCHPL*SLCPKLPLS*CLRC
QHHPLLRLSPLLKV*LQ*VNPTTVFPWRLWGIH
IL*LFPWTAVKYP*SSILSKKSVFDQG*QRLLL
DQRLPA*MGRKN*IWLRRWILLCLTQVKSWILRL
LETSLPSLRTR*MIILKCWMWQQWKQHCHFVKK
MMILSPCLAPGSILSSRSGTSQYLSLHQK*RSS
KRDWTLRKRKTREYMNWWTSGSPVQRSRWNLQNQ
SQSFQEPK**LELFQPQVWSHQNSGVRT*MRNW
EVLQLERLLKQMLPLGKAMRLHLQM*RQRHPLK
ACCLHHMAQIPLKIL*RQRLSTSLKCQTH*KKNQ
GLFLEAR*RMPQVRMRRKMVSVKRPA*RSLRKR
IKEKATCQKWIMNLL*ARVMMASAYTMLHCSHT
HWQTPSPAALLLHSSLSVVRIRKLFRHRKFGRKP
SCLYGELQLIIGMPMSSCSLLQMT*HLATTALC
RGLWICQLLRKT*KMD*SEAQLNFSVTLC*CFR
ML*CTIAQTMMSITWQWRCSEMSWNRSSNSWPRS
*LCKHPSLGSVLKVFEGEILPANRMLQRRTVSQ
WALLPSFSLSLWDTSGFGWILNKIIPMTLS*AM
TAGPSSAHGTPVWILMWATGGKLRIQRLRN*RKA
ARRENLVNCLLGMEAVRNLRKRQGKPATRTSST
FSLR*LI*WSPCASAATNQVKAAALHLVPDKKE
GKLKLAKEKGSSAERLKSFQLKETP**LKSHWEK
MESQRWLQLPQLFVQFRDYSQRVKRGRLSKNPK
GRTRVKYMCQRWKTSPLQASVMMPLTLRRLPWW
IHFSAMLPPQS*LI*ARMTLFRIICYLRRLSCQS
GR*LPVTGSAVHF*SLCQKGRPQGTRMW*KDPW
T*LA*REISLRVGFAPWPNSCET*C*CSKML*C
TMTLIIMYTIWLWRCGKKSWSRFRY*ISG*TKEK
AQVVWKENQLTQWMMENLFSNLELLS*LFLEFE
SLPEL*PREDPGTSLPCPHFLFQQE*YLNSQPT
SQRCMWT*YKEKKGKLRFGFMP*MLPTSLFHRLD
LKTIPLDLF*AFYSINKCIYTI

Sequence NM_006696

GGGTTTCGGCCCTTCCAGACCGTCTCTCCTCAGGGTTGGAGACTTCGGGGCCAAGATGGCGACGGGAACGGGCAAACACAAGCTGCTAAGCACTGGCCCC
ACAGAGCCATGGTCCATCCGAGAGAAGCTATGTTTAGCATCTTCTGTCATGAGAAGTGGCGATCAAAATTGGGTATCAGTTAGCAGAGCAATCAAGCCCT
TTGCAGAACCTGGCCGCCCTCCAGACTGGTTCTCTCAAAAACATTGTGCTTCCCAGTACTCGGAGCTTTTAGAGACCACTGAGACACCAAAACGGAAACG
AGGTGAAAAGGGAGAAGTGGTGGAAACTGTTGAAGATGTTATTGTTCGGAAATTGACTGCTGAGCGAGTTGAAGAACTAAAGAAAGTGATAAAGGAAACC
CAGGAGAGATATAGACGGCTAAAGAGAGATGCAGAACTAATTCAAGCTGGACACATGGACAGCAGACTGGATGAGCTTTGCAATGACATTGCAACGAAAA
AGAAATTGGAAGAAGAGGAGGCTGAAGTAAAGAGGAAGGCTACAGATGCTGCATACCAGGCTCGTCAAGCAGTAAAAACACCCCCCCGGAGGTTACCCAC
TGTGATGGTTCGCTCTCCTATAGATTCTGCCTCCCCAGGAGGTGATTATCCACTTGGGGACTTGACTCCAACCACTATGGAAGAGGCTACCTCTGGGGTA
ACCCCCGGGACTTTGCCGAGTACCCCAGTCACCTCGTTTCCTGGGATTCCTGACACCCTTCCTCCAGGCTCTGCACCCTTAGAAGCCCCCATGACCCCAG
TAACAGATGATTCACCCCAGAAAAAGATGCTTGGACAGAAAGCAACTCCACCCCCCTCCCCTCTGCTGTCAGAGCTCTTGAAGAAGGGCAGCCTCCTGCC
TACTAGCCCCAGACTGGTCAATGAGAGTGAAATGGCTGTGGCTTCTGGCCACCTGAACAGTACAGGTGTCCTCCTGGAGGTAGGCGGGGTCCTTCCCATG
ATACATGGTGGGGAGATACAGCAAACACCCAATACTGTTGCAGCCTCCCCTGCTGCATCAGGTGCTCCCACTCTTTCCCGGCTTTTAGAAGCTGGTCCTA
CACAGTTCACCACACCTCTTGCTTCCTTCACTACTGTTGCCAGTGAGCCTCCAGTTAAACTTGTGCCACCCCCTGTAGAGTCTGTGTCCCAAGCTACCAT
TGTCATGATGCCTGCGCTGCCAGCACCATCCTCTGCTCCGGCTGTCTCCACTACTGAAAGTGTAGCTCCAGTGAGTCAACCCGACAACTGTGTTCCCATG
GAGGCTGTGGGGGATCCACATACTGTGACTGTTTCCATGGACAGCAGTGAAATATCCATGATCATCAATTCTATCAAAGAAGAGTGTTTTCGATCAGGGG
TAGCAGAGGCTCCTGTTGGATCAAAGGCTCCCAGCATAGATGGGAAGGAAGAATTAGATCTGGCTGAGAAGATGGATATTGCTGTGTCTTACACAGGTGA
AGAGCTGGATTTTGAGACTGTTGGAGACATCATTGCCATCATTGAGGACAAGGTAGATGATCATCCTGAAGTGCTGGATGTGGCAGCAGTGGAAGCAGCA
CTGTCATTTTGTGAAGAAAATGATGATCCTCAGTCCCTGCCTGGCCCCTGGGAGCATCCTATCCAGCAGGAGCGGGACAAGCCAGTACCTCTCCCTGCAC
CAGAAATGACGGTCAAGCAAGAGAGACTGGACTTTGAGGAAACGGAAAACAAGGGAATACATGAACTGGTGGACATCAGGGAGCCCAGTGCAGAGATCAA
GGTGGAACCTGCAGAACCAGAGCCAGTCATTTCAGGAGCCGAAATAGTAGCTGGAGTTGTTCCAGCCACAAGTATGGAGCCACCAGAACTCAGGAGTCAG
GACTTAGATGAGGAACTGGGAAGTACTGCAGCTGGAGAGATTGTTGAAGCAGATGTTGCCATTGGGAAAGGCGATGAGACTCCACTTACAAATGTGAAGA
CAGAGGCATCCCCTGAAAGCATGTTGTCTCCATCACATGGCTCAAATCCCATTGAAGATCCTTTAGAGGCAGAGACTCAGCACAAGTTTGAAATGTCAGA
CTCATTGAAAGAAGAATCAGGGACTATTTTTGGAAGCCAGATAAAGGATGCCCCAGGTGAGGATGAGGAGGAAGATGGTGTCAGTGAAGCGGCCAGCCTA
GAGGAGCCTAAGGAAGAGGATCAAGGAGAAGGCTACTTGTCAGAAATGGATAATGAACCTCCTGTGAGCGAGAGTGATGATGGCTTCAGCATACACAATG
CTACACTGCAGTCACACACACTGGCAGACTCCATCCCCAGCAGCCCTGCTTCTTCACAGTTCTCTGTCTGTAGTGAGGATCAGGAAGCTATTCAGGCACA
GAAAATTTGGAAGAAAGCCATCATGCTTGTATGGAGAGCTGCAGCTAATCATAGGTATGCCAATGTCTTCCTGCAGCCTGTTACAGATGACATAGCACCT
GGCTACCACAGCATTGTGCAGAGGCCTATGGATTTGTCAACTATTAAGAAAAACATAGAAAATGGACTGATCCGAAGCACAGCTGAATTTCAGCGTGACA
TTATGCTGATGTTTCAGAATGCTGTAATGTACAATAGCTCAGACCATGATGTCTATCACATGGCAGTGGAGATGCAGCGAGATGTCTTGGAACAGATCCA
GCAATTCTTGGCCACGCAGTTGATTATGCAAACATCCGAGTCTGGGATCAGTGCTAAAAGTCTTCGAGGGAGAGATTCTACCCGCAAACAGGATGCTTCA
GAGAAGGACAGTGTCCCAATGGGCTCTCCTGCCTTCCTTCTCTCTCTCTTTGATGGAGGAACCAGGGGACGCCGCTGTGCCATTGAAGCAGATATGAAGA
TGAAAAAGTGAAGCCTCAGAGTTACCCTCTTTGAGCCGAACCTAAAATAAAAGTAAACAAGATAGAGCTTGGGCTTGCGGGCCCAGTTCCAGAGGTGGAA
GTTACAGAAGAGGAGGTACCTGGGCCACACGACATGAGCTGGAAAATCTCTCTTAGAGAGTTGGAGTAGCACAATTGCCTGTTTTAGGGCAGAAACCATG
GGCTATGTTAATGTCCTAATGTGTAGCTAGCAGATCGTAGCTAGTTTGTATTGTCTTGTCAATTGTACAGACTTTTTAAAAAAAACAACCACCAGTGAAA
TGTGTGTGTATACAATAAACTGAAAAAAAAAACTA
  • refseq_BRD8.F4 (forward primer)
  • refseq_BRD8.R4 (reverse primer)
  • Single exon skipping

Frame 0

GFRPFQTVSPQGWRLRGQDGDGNGQTQAAKHWP
HRAMVHPREAMFSIFCHEKWRSKLGIS*QSNQAL
CRTWPPSRLVLSKTLCFPVLGAFRDH*DTKTET
R*KGRSGGNC*RCYCSEIDC*AS*RTKESDKGN
PGEI*TAKERCRTNSSWTHGQQTG*ALQ*HCNEK
EIGRRGG*SKEEGYRCCIPGSSSSKNTPPEVTH
CDGSLSYRFCLPRR*LSTWGLDSNHYGRGYLWG
NPRDFAEYPSHLVSWDS*HPSSRLCTLRSPHDPS
NR*FTPEKDAWTESNSTPLPSAVRALEEGQPPA
Y*PQTGQ*E*NGCGFWPPEQYRCPPGGRRGPSH
DTWWGDTANTQYCCSLPCCIRCSHSFPAFRSWSY
TVHHTSCFLHYCCQ*ASS*TCATPCRVCVPSYH
CHDACAASTILCSGCLHY*KCSSSESTRQLCSH
GGCGGSTYCDCFHGQQ*NIHDHQFYQRRVFSIRG
SRGSCWIKGSQHRWEGRIRSG*EDGYCCVLHR*
RAGF*DCWRHHCHH*GQGR*SS*SAGCGSSGSS
TVIL*RK**SSVPAWPLGASYPAGAGQASTSPCT
RNDGQARETGL*GNGKQGNT*TGGHQGAQCRDQ
GGTCRTRASHFRSRNSSWSCSSHKYGATRTQES
GLR*GTGKYCSWRDC*SRCCHWERR*DSTYKCED
RGIP*KHVVSITWLKSH*RSFRGRDSAQV*NVR
LIERRIRDYFWKPDKGCPR*G*GGRWCQ*SGQP
RGA*GRGSRRRLLVRNG**TSCERE**WLQHTQC
YTAVTHTGRLHPQQPCFFTVLCL**GSGSYSGT
ENLEESHHACMESCS*S*VCQCLPAACYR*HST
WLPQHCAEAYGFVNY*EKHRKWTDPKHS*ISA*H
YADVSECCNVQ*LRP*CLSHGSGDAARCLGTDP
AILGHAVDYANIRVWDQC*KSSRERFYPQTGCF
REGQCPNGLSCLPSLSL*WRNQGTPLCH*SRYED
EKVKPQSYPL*AEPKIKVNKIELGLAGPVPEVE
VTEEEVPGPHDMSWKISLRELE*HNCLF*GRNH
GLC*CPNV*LADRS*FVLSCQLYRLFKKNNHQ*N
VCVYNKLKKKT

Frame 1

GFGPSRPSLLRVGDFGAKMATGTGKHKLLSTGP
TEPWSIREKLCLASSVMRSGDQNWVSVSRAIKP
FAEPGRPPDWFSQKHCASQYSELLETTETPKRKR
GEKGEVVETVEDVIVRKLTAERVEELKKVIKET
QERYRRLKRDAELIQAGHMDSRLDELCNDIATK
KKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPT
VMVRSPIDSASPGGDYPLGDLTPTTMEEATSGV
TPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTP
VTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLP
TSPRLVNESEMAVASGHLNSTGVLLEVGGVLPM
IHGGEIQQTPNTVAASPAASGAPTLSRLLEAGP
TQFTTPLASFTTVASEPPVKLVPPPVESVSQATI
VMMPALPAPSSAPAVSTTESVAPVSQPDNCVPM
EAVGDPHTVTVSMDSSEISMIINSIKEECFRSG
VAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGE
ELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAA
LSFCEENDDPQSLPGPWEHPIQQERDKPVPLPA
PEMTVKQERLDFEETENKGIHELVDIREPSAEIK
VEPAEPEPVISGAEIVAGVVPATSMEPPELRSQ
DLDEELGSTAAGEIVEADVAIGKGDETPLTNVK
TEASPESMLSPSHGSNPIEDPLEAETQHKFEMSD
SLKEESGTIFGSQIKDAPGEDEEEDGVSEAASL
EEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHN
ATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQ
KIWKKAIMLVWRAAANHRYANVFLQPVTDDIAP
GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRD
IMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQ
QFLATQLIMQTSESGISAKSLRGRDSTRKQDAS
EKDSVPMGSPAFLLSLFDGGTRGRRCAIEADMK
MKK*SLRVTLFEPNLK*K*TR*SLGLRAQFQRWK
LQKRRYLGHTT*AGKSLLESWSSTIACFRAETM
GYVNVLMCS*QIVASLYCLVNCTDFLKKTTTSE
MCVYTIN*KKKL

Frame 2

VSALPDRLSSGLETSGPRWRRERANTSC*ALAP
QSHGPSERSYV*HLLS*EVAIKIGYQLAEQSSP
LQNLAALQTGSLKNIVLPSTRSF*RPLRHQNGN
EVKREKWWKLLKMLLFGN*LLSELKN*RK**RKP
RRDIDG*REMQN*FKLDTWTADWMSFAMTLQRK
RNWKKRRLK*RGRLQMLHTRLVKQ*KHPPGGYP
L*WFALL*ILPPQEVIIHLGT*LQPLWKRLPLG*
PPGLCRVPQSPRFLGFLTPFLQALHP*KPP*PQ
*QMIHPRKRCLDRKQLHPPPLCCQSS*RRAASC
LLAPDWSMRVKWLWLLAT*TVQVSSWR*AGSFP*
YMVGRYSKHPILLQPPLLHQVLPLFPGF*KLVL
HSSPHLLLPSLLLPVSLQLNLCHPL*SLCPKLP
LS*CLRCQHHPLLRLSPLLKV*LQ*VNPTTVFPW
RLWGIHIL*LFPWTAVKYP*SSILSKKSVFDQG
*QRLLLDQRLPA*MGRKN*IWLRRWILLCLTQV
KSWILRLLETSLPSLRTR*MIILKCWMWQQWKQH
CHFVKKMMILSPCLAPGSILSSRSGTSQYLSLH
QK*RSSKRDWTLRKRKTREYMNWWTSGSPVQRS
RWNLQNQSQSFQEPK**LELFQPQVWSHQNSGVR
T*MRNWEVLQLERLLKQMLPLGKAMRLHLQM*R
QRHPLKACCLHHMAQIPLKIL*RQRLSTSLKCQ
TH*KKNQGLFLEAR*RMPQVRMRRKMVSVKRPA*
RSLRKRIKEKATCQKWIMNLL*ARVMMASAYTM
LHCSHTHWQTPSPAALLLHSSLSVVRIRKLFRH
RKFGRKPSCLYGELQLIIGMPMSSCSLLQMT*HL
ATTALCRGLWICQLLRKT*KMD*SEAQLNFSVT
LC*CFRML*CTIAQTMMSITWQWRCSEMSWNRS
SNSWPRS*LCKHPSLGSVLKVFEGEILPANRMLQ
RRTVSQWALLPSFSLSLMEEPGDAAVPLKQI*R
*KSEASELPSLSRT*NKSKQDRAWACGPSSRGG
SYRRGGTWATRHELENLS*RVGVAQLPVLGQKPW
AMLMS*CVASRS*LVCIVLSIVQTF*KKQPPVK
CVCIQ*TEKKN

Sequence NM_183359

GGGTTTCGGCCCTTCCAGACCGTCTCTCCTCAGGGTTGGAGACTTCGGGGCCAAGATGGCGACGGGAACGGGCAAACACAAGCTGCTAAGCACTGGCCCC
ACAGAGCCATGGTCCATCCGAGAGAAGCTATGTTTAGCATCTTCTGTCATGAGAAGTGGCGATCAAAATTGGGTATCAGTTAGCAGAGCAATCAAGCCCT
TTGCAGAACCTGGCCGCCCTCCAGACTGGTTCTCTCAAAAACATTGTGCTTCCCAGTACTCGGAGCTTTTAGAGACCACTGAGACACCAAAACGGAAACG
AGGTGAAAAGGGAGAAGTGGTGGAAACTGTTGAAGATGTTATTGTTCGGAAATTGACTGCTGAGCGAGTTGAAGAACTAAAGAAAGTGATAAAGGAAACC
CAGGAGAGATATAGACGGCTAAAGAGAGATGCAGAACTAATTCAAGCTGGACACATGGACAGCAGACTGGATGAGCTTTGCAATGACATTGAAAAAGAAA
TTGGAAGAAGAGGAGGCTGAAGTAAAGAGGAAGGCTACAGATGCTGCATACCAGGCTCGTCAAGCAGTAAAAACACCCCCCCGGAGGTTACCCACTGTGA
TGGTTCGCTCTCCTATAGATTCTGCCTCCCCAGGAGGTGATTATCCACTTGGGGACTTGACTCCAACCACTATGGAAGAGGCTACCTCTGGGGTAACCCC
CGGGACTTTGCCGAGTACCCCAGTCACCTCGTTTCCTGGGATTCCTGACACCCTTCCTCCAGGCTCTGCACCCTTAGAAGCCCCCATGACCCCAGTAACA
GATGATTCACCCCAGAAAAAGATGCTTGGACAGAAAGCAACTCCACCCCCCTCCCCTCTGCTGTCAGAGCTCTTGAAGAAGGGCAGCCTCCTGCCTACTA
GCCCCAGACTGGTCAATGAGAGTGAAATGGCTGTGGCTTCTGGCCACCTGAACAGTACAGGTGTCCTCCTGGAGGTAGGCGGGGTCCTTCCCATGATACA
TGGTGGGGAGATACAGCAAACACCCAATACTGTTGCAGCCTCCCCTGCTGCATCAGAGTCTGTGTCCCAAGCTACCATTGTCATGATGCCTGCGCTGCCA
GCACCATCCTCTGCTCCGGCTGTCTCCACTACTGAAAGTGTAGCTCCAGTGAGTCAACCCGACAACTGTGTTCCCATGGAGGCTGTGGGGGATCCACATA
CTGTGACTGTTTCCATGGACAGCAGTGAAATATCCATGATCATCAATTCTATCAAAGAAGAGTGTTTTCGATCAGGGGTAGCAGAGGCTCCTGTTGGATC
AAAGGCTCCCAGCATAGATGGGAAGGAAGAATTAGATCTGGCTGAGAAGATGGATATTGCTGTGTCTTACACAGGTGAAGAGCTGGATTTTGAGACTGTT
GGAGACATCATTGCCATCATTGAGGACAAGGTAGATGATCATCCTGAAGTGCTGGATGTGGCAGCAGTGGAAGCAGCACTGTCATTTTGTGAAGAAAATG
ATGATCCTCAGTCCCTGCCTGGCCCCTGGGAGCATCCTATCCAGCAGGAGCGGGACAAGCCAGTACCTCTCCCTGCACCAGAAATGACGGTCAAGCAAGA
GAGACTGGACTTTGAGGAAACGGAAAACAAGGGAATACATGAACTGGTGGACATCAGGGAGCCCAGTGCAGAGATCAAGGTGGAACCTGCAGAACCAGAG
CCAGTCATTTCAGGAGCCGAAATAGTAGCTGGAGTTGTTCCAGCCACAAGTATGGAGCCACCAGAACTCAGGAGTCAGGACTTAGATGAGGAACTGGGAA
GTACTGCAGCTGGAGAGATTGTTGAAGCAGATGTTGCCATTGGGAAAGGCGATGAGACTCCACTTACAAATGTGAAGACAGAGGCATCCCCTGAAAGCAT
GTTGTCTCCATCACATGGCTCAAATCCCATTGAAGATCCTTTAGAGGCAGAGACTCAGCACAAGTTTGAAATGTCAGACTCATTGAAAGAAGAATCAGGG
ACTATTTTTGGAAGCCAGATAAAGGATGCCCCAGGTGAGGATGAGGAGGAAGATGGTGTCAGTGAAGCGGCCAGCCTAGAGGAGCCTAAGGAAGAGGATC
AAGGAGAAGGCTACTTGTCAGAAATGGATAATGAACCTCCTGTGAGCGAGAGTGATGATGGCTTCAGCATACACAATGCTACACTGCAGTCACACACACT
GGCAGACTCCATCCCCAGCAGCCCTGCTTCTTCACAGTTCTCTGTCTGTAGTGAGGATCAGGAAGCTATTCAGGCACAGAAAATTTGGAAGAAAGCCATC
ATGCTTGTATGGAGAGCTGCAGCTAATCATAGGTATGCCAATGTCTTCCTGCAGCCTGTTACAGATGACATAGCACCTGGCTACCACAGCATTGTGCAGA
GGCCTATGGATTTGTCAACTATTAAGAAAAACATAGAAAATGGACTGATCCGAAGCACAGCTGAATTTCAGCGTGACATTATGCTGATGTTTCAGAATGC
TGTAATGTACAATAGCTCAGACCATGATGTCTATCACATGGCAGTGGAGATGCAGCGAGATGTCTTGGAACAGATCCAGCAATTCTTGGCCACGCAGTTG
ATTATGCAAACATCCGAGTCTGGGATCAGTGCTAAAAGTCTTCGAGGGAGAGATTCTACCCGCAAACAGGATGCTTCAGAGAAGGATGGAGGAACCAGGG
GACGCCGCTGTGCCATTGAAGCAGATATGAAGATGAAAAAGTGAAGCCTCAGAGTTACCCTCTTTGAGCCGAACCTAAAATAAAAGTAAACAAGATAGAG
CTTGGGCTTGCGGGCCCAGTTCCAGAGGTGGAAGTTACAGAAGAGGAGGTACCTGGGCCACACGACATGAGCTGGAAAATCTCTCTTAGAGAGTTGGAGT
AGCACAATTGCCTGTTTTAGGGCAGAAACCATGGGCTATGTTAATGTCCTAATGTGTAGCTAGCAGATCGTAGCTAGTTTGTATTGTCTTGTCAATTGTA
CAGACTTTTTAAAAAAAACAACCACCAGTGAAATGTGTGTGTATACAATAAACTGAAAAAAAAAACTA
  • refseq_BRD8.F4 (forward primer)
  • refseq_BRD8.R4 (reverse primer)
  • Single exon skipping

Frame 0

GFRPFQTVSPQGWRLRGQDGDGNGQTQAAKHWP
HRAMVHPREAMFSIFCHEKWRSKLGIS*QSNQAL
CRTWPPSRLVLSKTLCFPVLGAFRDH*DTKTET
R*KGRSGGNC*RCYCSEIDC*AS*RTKESDKGN
PGEI*TAKERCRTNSSWTHGQQTG*ALQ*H*KRN
WKKRRLK*RGRLQMLHTRLVKQ*KHPPGGYPL*
WFALL*ILPPQEVIIHLGT*LQPLWKRLPLG*P
PGLCRVPQSPRFLGFLTPFLQALHP*KPP*PQ*Q
MIHPRKRCLDRKQLHPPPLCCQSS*RRAASCLL
APDWSMRVKWLWLLAT*TVQVSSWR*AGSFP*Y
MVGRYSKHPILLQPPLLHQSLCPKLPLS*CLRCQ
HHPLLRLSPLLKV*LQ*VNPTTVFPWRLWGIHI
L*LFPWTAVKYP*SSILSKKSVFDQG*QRLLLD
QRLPA*MGRKN*IWLRRWILLCLTQVKSWILRLL
ETSLPSLRTR*MIILKCWMWQQWKQHCHFVKKM
MILSPCLAPGSILSSRSGTSQYLSLHQK*RSSK
RDWTLRKRKTREYMNWWTSGSPVQRSRWNLQNQS
QSFQEPK**LELFQPQVWSHQNSGVRT*MRNWE
VLQLERLLKQMLPLGKAMRLHLQM*RQRHPLKA
CCLHHMAQIPLKIL*RQRLSTSLKCQTH*KKNQG
LFLEAR*RMPQVRMRRKMVSVKRPA*RSLRKRI
KEKATCQKWIMNLL*ARVMMASAYTMLHCSHTH
WQTPSPAALLLHSSLSVVRIRKLFRHRKFGRKPS
CLYGELQLIIGMPMSSCSLLQMT*HLATTALCR
GLWICQLLRKT*KMD*SEAQLNFSVTLC*CFRM
L*CTIAQTMMSITWQWRCSEMSWNRSSNSWPRS*
LCKHPSLGSVLKVFEGEILPANRMLQRRMEEPG
DAAVPLKQI*R*KSEASELPSLSRT*NKSKQDR
AWACGPSSRGGSYRRGGTWATRHELENLS*RVGV
AQLPVLGQKPWAMLMS*CVASRS*LVCIVLSIV
QTF*KKQPPVKCVCIQ*TEKKN

Frame 1

GFGPSRPSLLRVGDFGAKMATGTGKHKLLSTGP
TEPWSIREKLCLASSVMRSGDQNWVSVSRAIKP
FAEPGRPPDWFSQKHCASQYSELLETTETPKRKR
GEKGEVVETVEDVIVRKLTAERVEELKKVIKET
QERYRRLKRDAELIQAGHMDSRLDELCNDIEKE
IGRRGG*SKEEGYRCCIPGSSSSKNTPPEVTHCD
GSLSYRFCLPRR*LSTWGLDSNHYGRGYLWGNP
RDFAEYPSHLVSWDS*HPSSRLCTLRSPHDPSN
R*FTPEKDAWTESNSTPLPSAVRALEEGQPPAY*
PQTGQ*E*NGCGFWPPEQYRCPPGGRRGPSHDT
WWGDTANTQYCCSLPCCIRVCVPSYHCHDACAA
STILCSGCLHY*KCSSSESTRQLCSHGGCGGSTY
CDCFHGQQ*NIHDHQFYQRRVFSIRGSRGSCWI
KGSQHRWEGRIRSG*EDGYCCVLHR*RAGF*DC
WRHHCHH*GQGR*SS*SAGCGSSGSSTVIL*RK*
*SSVPAWPLGASYPAGAGQASTSPCTRNDGQAR
ETGL*GNGKQGNT*TGGHQGAQCRDQGGTCRTR
ASHFRSRNSSWSCSSHKYGATRTQESGLR*GTGK
YCSWRDC*SRCCHWERR*DSTYKCEDRGIP*KH
VVSITWLKSH*RSFRGRDSAQV*NVRLIERRIR
DYFWKPDKGCPR*G*GGRWCQ*SGQPRGA*GRGS
RRRLLVRNG**TSCERE**WLQHTQCYTAVTHT
GRLHPQQPCFFTVLCL**GSGSYSGTENLEESH
HACMESCS*S*VCQCLPAACYR*HSTWLPQHCAE
AYGFVNY*EKHRKWTDPKHS*ISA*HYADVSEC
CNVQ*LRP*CLSHGSGDAARCLGTDPAILGHAV
DYANIRVWDQC*KSSRERFYPQTGCFREGWRNQG
TPLCH*SRYEDEKVKPQSYPL*AEPKIKVNKIE
LGLAGPVPEVEVTEEEVPGPHDMSWKISLRELE
*HNCLF*GRNHGLC*CPNV*LADRS*FVLSCQLY
RLFKKNNHQ*NVCVYNKLKKKT

Frame 2

VSALPDRLSSGLETSGPRWRRERANTSC*ALAP
QSHGPSERSYV*HLLS*EVAIKIGYQLAEQSSP
LQNLAALQTGSLKNIVLPSTRSF*RPLRHQNGN
EVKREKWWKLLKMLLFGN*LLSELKN*RK**RKP
RRDIDG*REMQN*FKLDTWTADWMSFAMTLKKK
LEEEEAEVKRKATDAAYQARQAVKTPPRRLPTV
MVRSPIDSASPGGDYPLGDLTPTTMEEATSGVTP
GTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVT
DDSPQKKMLGQKATPPPSPLLSELLKKGSLLPT
SPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIH
GGEIQQTPNTVAASPAASESVSQATIVMMPALP
APSSAPAVSTTESVAPVSQPDNCVPMEAVGDPH
TVTVSMDSSEISMIINSIKEECFRSGVAEAPVGS
KAPSIDGKEELDLAEKMDIAVSYTGEELDFETV
GDIIAIIEDKVDDHPEVLDVAAVEAALSFCEEN
DDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQE
RLDFEETENKGIHELVDIREPSAEIKVEPAEPE
PVISGAEIVAGVVPATSMEPPELRSQDLDEELG
STAAGEIVEADVAIGKGDETPLTNVKTEASPESM
LSPSHGSNPIEDPLEAETQHKFEMSDSLKEESG
TIFGSQIKDAPGEDEEEDGVSEAASLEEPKEED
QGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTL
ADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAI
MLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQ
RPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNA
VMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQL
IMQTSESGISAKSLRGRDSTRKQDASEKDGGTR
GRRCAIEADMKMKK*SLRVTLFEPNLK*K*TR*S
LGLRAQFQRWKLQKRRYLGHTT*AGKSLLESWS
STIACFRAETMGYVNVLMCS*QIVASLYCLVNC
TDFLKKTTTSEMCVYTIN*KKKL

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