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Sequences

Sequence NM_001881

refseq_CREM.F2 (forward primer)
refseq_CREM.R2 (reverse primer)
Single exon skipping

Frame 0

AGGRQGAEFEPGFFSSGPPPGGRPGVGEGRTGR EDAVRSAAALLLVRGRQGGRGYRITADVRTTWGR CRLRVAGRRRRC*AAVGLAVSTSSRP*SVTRSA T*IPLRRTNDHGNS*IPA*WKYNSFFDREQVCS CADSDWPKFNPCFSSGSSNCRDR*ICRIRRCN*F S*T*RNPFTKTLL*ENTE*TVL*CAWCSQD*RR EIRGRRNTT*YCYHGSTN*HISD*HGAIQYVCC NSI*YSASFKSSLVILKQLRFWH*IVPF*NASLI PKLYHRMKVYVKK*DLCIDSCHIILKSKNFDCR I*KKILG*KGEFFLFTCLY*SLVKHCFCCLYDA CEHKCLYFILVGFCYPQLHTILTNLRVF*SMFSM FHYSLLC*FVLQFFLKENGKMI*FFKL*QLDR* FYLKFYTLKALNKQIHSHS

Frame 1

LAAGRGRSSSLDFFPRGLPREAVPAWGRGGRGG RTRFGRLQRYFWSGVGREAAATASQLT*GLRGA AAGSGLLGGGAAAERRSGSPSPPPRVRNQ*RGPL RKSLCGGQMTMETVESQHDGSITASLTESKSAH VQTQTGQNSIPALAQVAAIAETDESAESEGVID SHKRREILSRRPSYRKILNELSSDVPGVPKIEEE RSEEEGTPPSIATMAVPTSIYQTSTGQYSMYAA IRYDTVLALSLL*LY*SNSGFGIKLFHFKMHH* YLNCIIE*KYMLKSEIFVLTAVI*F*KVKILTAE YRRKFWGKKENFSYLHVYINL**NIVFVVFMMH ANINVCISFLLAFVTHNYILFLLI*EFSKVCFQ CFTTLYSVNLCYSFS*KRMEK*FNFLNCSNWIDN FI*NFTH*KL*INRYIHI

Frame 2

WRPAGGGVRAWIFFLGASPGRPSRRGGGEDGAG GRGSVGCSATFGPGSAGRPRLPHHS*REDYVGP LPAPGCWAAAPLLSGGRARRLHLLASVISDEVR YVNPFAADK*PWKQLNPSMMEV*QLL*QRASLLM CRLRLAKIQSLL*LR*QQLQRQMNLQNQKV*LI LINVEKSFHEDPLIGKY*MNCPLMCLVFPRLKK RDQRKKEHHLVLLPWQYQLAYIRLARGNTVCMLQ FDMIQC*L*VFSSYIEATQVLALNCSILKCIIN T*TVS*NESIC*KVRSLY*QLSYNFEK*KF*LP NIEENFGVKRRIFPIYMFILISSKTLFLLSL*CM RT*MSVFHSCWLLLPTITYYSY*SESFLKYVFN VSLLSTLLICATVFPKREWKNDLIF*TVAIG*I ILFEILHTESSK*TDTFTF

Sequence NM_183013

GCTGGCGGCCGGCAGGGGGCGGAGTTCGAGCCTGGATTTTTTTCCTCGGGGCCTCCCCCGGGAGGCCGTCCCGGCGTGGGGGAGGGGAGGACGGGGCGGG AGGACGCGGTTCGGTCGGCTGCAGCGCTACTTTTGGTCCGGGGTCGGCAGGGAGGCCGCGGCTACCGCATCACAGCTGACGTGAGGACTACGTGGGGCCG CTGCCGGCTCCGGGTTGCTGGGCGGCGGCGCCGCTGCTGAGCGGCGGTCGGGCTCGCCGTCTCCACCTCCTCGCGTCCGTAATCAGTGACGAGGTCCGCT ACGTAAATCCCTTTGCGGCGGGATAAATAAAGAAAACAGGAAAGGAGGAAAGCATTGATTACAAATATCTTAACAATGAGCAAATGTGCAAGGAAAAAAT ATATTAAGACAAATCCAAGACAAATGACCATGGAAACAGTTGAATCCCAGCATGATGGAAGTATAACAGCTTCTTTGACAGAGAGCAAGTCTGCTCATGT GCAGACTCAGACTGGCCAAAATTCAATCCCTGCTTTAGCTCAGGTAGCAGCAATTGCAGAGACAGATGAATCTGCAGAATCAGAAGGTGTAATTGATTCT CATAAACGTAGAGAAATCCTTTCACGAAGACCCTCTTATAGGAAAATACTGAATGAACTGTCCTCTGATGTGCCTGGTGTTCCCAAGATTGAAGAAGAGA GATCAGAGGAAGAAGGAACACCACCTAGTATTGCTACCATGGCAGTACCAACTAGCATATATCAGACTAGCACGGGGCAATACAATGAGGAAACTGAACT TGCCCCAAGTCACATGGCTGCTGCCACTGGTGACATGCCAACTTACCAGATCCGAGCTCCTACTGCTGCTTTGCCACAGGGAGTGGTGATGGCTGCATCG CCCGGAAGTTTGCACAGTCCCCAGCAGCTGGCAGAAGAAGCAACACGCAAACGAGAGCTGAGGCTAATGAAAAACAGGGAAGCTGCCCGGGAGTGTCGCA GGAAGAAGAAAGAATATGTCAAATGTCTTGAAAATCGTGTGGCTGTGCTTGAAAACCAAAACAAGACTCTCATTGAGGAACTCAAGGCCCTCAAAGATCT TTATTGCCATAAAGTAGAGTAACTGTCTTTGACTTGGACCTTGTTTACTCTAATCAAGGCAGGAGATGCAGCAGTCCTACTTATTGCCATGTGGACTTGT GGGAAGGACACGTGTGACCCTTAAGAATCCAGTTTGGATTAGTGTTTGAAATTGAATTGGGAATGTTGTTCCAGGATGTGGAATGCAGCCGTGATCACAC TTACCGAGCTTACTTTGATCTGTTTGTCAATAGCATGCAAAAAATGCTTTGTTTGCCCTTTGCTTCTGCTTTTTTTCAGGGAAGCTGCCAAAGAATGTCG ACGTCGAAAGAAAGAATATGTAAAATGTCTGGAGAGCCGAGTTGCAGTGCTGGAAGTCCAGAACAAGAAGCTTATAGAGGAACTTGAAACCTTGAAAGAC ATTTGTTCTCCCAAAACAGATTACTAGAAATATTTAACTATGAACTGAAGGCAGCATGTATAGTTGCTTTTGAAGGAATACAATATATAGCTGGCAAGAA TGGTGGCTTCTTTTCTTTGTATCATTCATCTTCTTCTTTAATCACTTAACATTCCTAAAATGCTTCACTGTACGTAGTTAAGTCGTAGCTATAACTTCAA ATTTTTTAAAAGAGACAAACTGTAAAAAATGTGTGTATTCTTAAAATGCAATATTTGTAAGGCTTGTTCCAATGCCACATACTTGCAGCTCCCATTCTAT GTGTCATCAATAGTGTCCTATGCAATAAAATTATTTGCAGGTCTTTAAATCATTTTAGGAAAGGATGATCAAAAATAATGCATCCAGCAGTACAATAAAA GTAAACCACAAAAAAATACCTCAGGAAAGAATAGAAAGAAAGTCTATCTAATGACATGCCTATATGAGAAGAATAGCCTAGATATGAATATATGGCATTT GCAGATTTTTATATTAGTTGCTTTGTTAAAAAAAAAAAGATTGTATTGCTGTCCTTGAATGCCATAGTCAAAGAGAGTTTTTAATAGAACCATGTTGGTT GCACTTTGTAGTGTTTGGTGCTCATTTAAATATCTGAACATTTACTACAGTTTTTAACTCTACTGTGTAATATAAAAGATCTTGCAGAAGTTCTTAGTGT TGGTTTAATATTACCTAATGAAAGTGATGACATATTTTTTATATCTGGAATGAGCCTGTTGGGATCGCATTGCATACCTTCGGGGTACAAGTCAGTTTCT ACACTGGGTGCTGATCCTTGCACGCGCCCTTTCTACCATCTCACGGTGGGGATGGCCGCAGGGCTGTGCACCCAGAAGAAGATGGCTGTTAGCGTTTCGG CCTTCATAATGGCCTGAGACTTTCTTTCTGTAGGTGGTCTGGAGCTGTCCGGCTGGTGGCCCCCTATTTTGCCATTTAGCGAACAACCACAGGAATTTTA AAAACAAAAACATCCCAAGATTTTTTCATTTCAAAATGCTTCAAAGTCCACATTAGATCAGATACTCCGCTGTCGGCACATTCAGCTGAGGTTCATTACA ATCGAGACTGCAATGTGATCTATGTTTCATCTTGTTTTTATAATAAAAAGCTTCAGGGAACAAGCCCAAAGCCCTCACCACA

refseq_CREM.F2 (forward primer)
refseq_CREM.R2 (reverse primer)
Single exon skipping

Frame 0

AGGRQGAEFEPGFFSSGPPPGGRPGVGEGRTGR EDAVRSAAALLLVRGRQGGRGYRITADVRTTWGR CRLRVAGRRRRC*AAVGLAVSTSSRP*SVTRSA T*IPLRRDK*RKQERRKALITNILTMSKCARKK YIKTNPRQMTMETVESQHDGSITASLTESKSAHV QTQTGQNSIPALAQVAAIAETDESAESEGVIDS HKRREILSRRPSYRKILNELSSDVPGVPKIEEE RSEEEGTPPSIATMAVPTSIYQTSTGQYNEETEL APSHMAAATGDMPTYQIRAPTAALPQGVVMAAS PGSLHSPQQLAEEATRKRELRLMKNREAARECR RKKKEYVKCLENRVAVLENQNKTLIEELKALKDL YCHKVE*LSLTWTLFTLIKAGDAAVLLIAMWTC GKDTCDP*ESSLD*CLKLNWECCSRMWNAAVIT LTELTLICLSIACKKCFVCPLLLLFFREAAKECR RRKKEYVKCLESRVAVLEVQNKKLIEELETLKD ICSPKTDY*KYLTMN*RQHV*LLLKEYNI*LAR MVASFLCIIHLLL*SLNIPKMLHCT*LSRSYNFK FFKRDKL*KMCVFLKCNICKACSNATYLQLPFY VSSIVSYAIKLFAGL*IILGKDDQK*CIQQYNK SKPQKNTSGKNRKKVYLMTCLYEKNSLDMNIWHL QIFILVALLKKKRLYCCP*MP*SKRVFNRTMLV ALCSVWCSFKYLNIYYSF*LYCVI*KILQKFLV LV*YYLMKVMTYFLYLE*ACWDRIAYLRGTSQFL HWVLILARALSTISRWGWPQGCAPRRRWLLAFR PS*WPETFFL*VVWSCPAGGPLFCHLANNHRNF KNKNIPRFFHFKMLQSPH*IRYSAVGTFS*GSLQ SRLQCDLCFILFL**KASGNKPKALTT

Frame 1

LAAGRGRSSSLDFFPRGLPREAVPAWGRGGRGG RTRFGRLQRYFWSGVGREAAATASQLT*GLRGA AAGSGLLGGGAAAERRSGSPSPPPRVRNQ*RGPL RKSLCGGINKENRKGGKH*LQIS*Q*ANVQGKN ILRQIQDK*PWKQLNPSMMEV*QLL*QRASLLM CRLRLAKIQSLL*LR*QQLQRQMNLQNQKV*LIL INVEKSFHEDPLIGKY*MNCPLMCLVFPRLKKR DQRKKEHHLVLLPWQYQLAYIRLARGNTMRKLN LPQVTWLLPLVTCQLTRSELLLLLCHREW*WLHR PEVCTVPSSWQKKQHANES*G**KTGKLPGSVA GRRKNMSNVLKIVWLCLKTKTRLSLRNSRPSKI FIAIK*SNCL*LGPCLL*SRQEMQQSYLLPCGLV GRTRVTLKNPVWISV*N*IGNVVPGCGMQP*SH LPSLL*SVCQ*HAKNALFALCFCFFSGKLPKNV DVERKNM*NVWRAELQCWKSRTRSL*RNLKP*KT FVLPKQITRNI*L*TEGSMYSCF*RNTIYSWQE WWLLFFVSFIFFFNHLTFLKCFTVRS*VVAITS NFLKETNCKKCVYS*NAIFVRLVPMPHTCSSHSM CHQ*CPMQ*NYLQVFKSF*ERMIKNNASSSTIK VNHKKIPQERIERKSI**HAYMRRIA*I*IYGI CRFLY*LLC*KKKDCIAVLECHSQREFLIEPCWL HFVVFGAHLNI*TFTTVFNSTV*YKRSCRSS*C WFNIT**K**HIFYIWNEPVGIALHTFGVQVSF YTGC*SLHAPFLPSHGGDGRRAVHPEEDGC*RFG LHNGLRLSFCRWSGAVRLVAPYFAI*RTTTGIL KTKTSQDFFISKCFKVHIRSDTPLSAHSAEVHY NRDCNVIYVSSCFYNKKLQGTSPKPSP

Frame 2

WRPAGGGVRAWIFFLGASPGRPSRRGGGEDGAG GRGSVGCSATFGPGSAGRPRLPHHS*REDYVGP LPAPGCWAAAPLLSGGRARRLHLLASVISDEVR YVNPFAAG*IKKTGKEESIDYKYLNNEQMCKEKI Y*DKSKTNDHGNS*IPA*WKYNSFFDREQVCSC ADSDWPKFNPCFSSGSSNCRDR*ICRIRRCN*F S*T*RNPFTKTLL*ENTE*TVL*CAWCSQD*RRE IRGRRNTT*YCYHGSTN*HISD*HGAIQ*GN*T CPKSHGCCHW*HANLPDPSSYCCFATGSGDGCI ARKFAQSPAAGRRSNTQTRAEANEKQGSCPGVSQ EEERICQMS*KSCGCA*KPKQDSH*GTQGPQRS LLP*SRVTVFDLDLVYSNQGRRCSSPTYCHVDL WEGHV*PLRIQFGLVFEIELGMLFQDVECSRDHT YRAYFDLFVNSMQKMLCLPFASAFFQGSCQRMS TSKERICKMSGEPSCSAGSPEQEAYRGT*NLER HLFSQNRLLEIFNYELKAACIVAFEGIQYIAGKN GGFFSLYHSSSSLIT*HS*NASLYVVKS*L*LQ IF*KRQTVKNVCILKMQYL*GLFQCHILAAPIL CVINSVLCNKIICRSLNHFRKG*SKIMHPAVQ*K *TTKKYLRKE*KESLSNDMPI*EE*PRYEYMAF ADFYISCFVKKKKIVLLSLNAIVKESF**NHVG CTL*CLVLI*ISEHLLQFLTLLCNIKDLAEVLSV GLILPNESDDIFFISGMSLLGSHCIPSGYKSVS TLGADPCTRPFYHLTVGMAAGLCTQKKMAVSVS AFIMA*DFLSVGGLELSGWWPPILPFSEQPQEF* KQKHPKIFSFQNASKSTLDQILRCRHIQLRFIT IETAM*SMFHLVFIIKSFREQAQSPHH