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Sequences

Sequence NM_183060

GACCCGCCTGCCTCCTCGCGAACTTGGGACGAGTTGGAAAATCCTCCCTGAGAGAGCCGTGCGGCTCAGGGGAGCGGTTTAACTCGGAAAAGGAAAAGGA
ATCCAGAAACAAATGACCATGGAAACAGTTGAATCCCAGCATGATGGAAGTATAACAGCTTCTTTGACAGAGAGCAAGTCTGCTCATGTGCAGACTCAGA
CTGGCCAAAATTCAATCCCTGCTTTAGCTCAGGTAGCAGCAATTGCAGAGACAGATGAATCTGCAGAATCAGAAGGTGTAATTGATTCTCATAAACGTAG
AGAAATCCTTTCACGAAGACCCTCTTATAGGAAAATACTGAATGAACTGTCCTCTGATGTGCCTGGTGTTCCCAAGATTGAAGAAGAGAGATCAGAGGAA
GAAGGAACACCACCTAGTATTGCTACCATGGCAGTACCAACTAGCATATATCAGACTAGCACGGGGCAATACACTGCCACTGGTGACATGCCAACTTACC
AGATCCGAGCTCCTACTGCTGCTTTGCCACAGGGAGTGGTGATGGCTGCATCGCCCGGAAGTTTGCACAGTCCCCAGCAGCTGGCAGAAGAAGCAACACG
CAAACGAGAGCTGAGGCTAATGAAAAACAGGGAAGCTGCCAAAGAATGTCGACGTCGAAAGAAAGAATATGTAAAATGTCTGGAGAGCCGAGTTGCAGTG
CTGGAAGTCCAGAACAAGAAGCTTATAGAGGAACTTGAAACCTTGAAAGACATTTGTTCTCCCAAAACAGATTACTAGAAATATTTAACTATGAACTGAA
GGCAGCATGTATAGTTGCTTTTGAAGGAATACAATATATAGCTGGCAAGAATGGTGGCTTCTTTTCTTTGTATCATTCATCTTCTTCTTTAATCACTTAA
CATTCCTAAAATGCTTCACTGTACGTAGTTAAGTCGTAGCTATAACTTCAAATTTTTTAAAAGAGACAAACTGTAAAAAATGTGTGTATTCTTAAAATGC
AATATTTGTAAGGCTTGTTCCAATGCCACATACTTGCAGCTCCCATTCTATGTGTCATCAATAGTGTCCTATGCAATAAAATTATTTGCAGGTCTTTAAA
TCATTTTAGGAAAGGATGATCAAAAATAATGCATCCAGCAGTACAATAAAAGTAAACCACAAAAAAATACCTCAGGAAAGAATAGAAAGAAAGTCTATCT
AATGACATGCCTATATGAGAAGAATAGCCTAGATATGAATATATGGCATTTGCAGATTTTTATATTAGTTGCTTTGTTAAAAAAAAAAAGATTGTATTGC
TGTCCTTGAATGCCATAGTCAAAGAGAGTTTTTAATAGAACCATGTTGGTTGCACTTTGTAGTGTTTGGTGCTCATTTAAATATCTGAACATTTACTACA
GTTTTTAACTCTACTGTGTAATATAAAAGATCTTGCAGAAGTTCTTAGTGTTGGTTTAATATTACCTAATGAAAGTGATGACATATTTTTTATATCTGGA
ATGAGCCTGTTGGGATCGCATTGCATACCTTCGGGGTACAAGTCAGTTTCTACACTGGGTGCTGATCCTTGCACGCGCCCTTTCTACCATCTCACGGTGG
GGATGGCCGCAGGGCTGTGCACCCAGAAGAAGATGGCTGTTAGCGTTTCGGCCTTCATAATGGCCTGAGACTTTCTTTCTGTAGGTGGTCTGGAGCTGTC
CGGCTGGTGGCCCCCTATTTTGCCATTTAGCGAACAACCACAGGAATTTTAAAAACAAAAACATCCCAAGATTTTTTCATTTCAAAATGCTTCAAAGTCC
ACATTAGATCAGATACTCCGCTGTCGGCACATTCAGCTGAGGTTCATTACAATCGAGACTGCAATGTGATCTATGTTTCATCTTGTTTTTATAATAAAAA
GCTTCAGGGAACAAGCCCAAAGCCCTCACCACA
  • refseq_CREM.F7 (forward primer)
  • refseq_CREM.R5 (reverse primer)
  • Single exon skipping

Frame 0

DPPASSRTWDELENPP*ESRAAQGSGLTRKRKR
NPETNDHGNS*IPA*WKYNSFFDREQVCSCADSD
WPKFNPCFSSGSSNCRDR*ICRIRRCN*FS*T*
RNPFTKTLL*ENTE*TVL*CAWCSQD*RREIRG
RRNTT*YCYHGSTN*HISD*HGAIHCHW*HANLP
DPSSYCCFATGSGDGCIARKFAQSPAAGRRSNT
QTRAEANEKQGSCQRMSTSKERICKMSGEPSCS
AGSPEQEAYRGT*NLERHLFSQNRLLEIFNYELK
AACIVAFEGIQYIAGKNGGFFSLYHSSSSLIT*
HS*NASLYVVKS*L*LQIF*KRQTVKNVCILKM
QYL*GLFQCHILAAPILCVINSVLCNKIICRSLN
HFRKG*SKIMHPAVQ*K*TTKKYLRKE*KESLS
NDMPI*EE*PRYEYMAFADFYISCFVKKKKIVL
LSLNAIVKESF**NHVGCTL*CLVLI*ISEHLLQ
FLTLLCNIKDLAEVLSVGLILPNESDDIFFISG
MSLLGSHCIPSGYKSVSTLGADPCTRPFYHLTV
GMAAGLCTQKKMAVSVSAFIMA*DFLSVGGLELS
GWWPPILPFSEQPQEF*KQKHPKIFSFQNASKS
TLDQILRCRHIQLRFITIETAM*SMFHLVFIIK
SFREQAQSPHH

Frame 1

TRLPPRELGTSWKILPERAVRLRGAV*LGKGKG
IQKQMTMETVESQHDGSITASLTESKSAHVQTQ
TGQNSIPALAQVAAIAETDESAESEGVIDSHKRR
EILSRRPSYRKILNELSSDVPGVPKIEEERSEE
EGTPPSIATMAVPTSIYQTSTGQYTATGDMPTY
QIRAPTAALPQGVVMAASPGSLHSPQQLAEEATR
KRELRLMKNREAAKECRRRKKEYVKCLESRVAV
LEVQNKKLIEELETLKDICSPKTDY*KYLTMN*
RQHV*LLLKEYNI*LARMVASFLCIIHLLL*SLN
IPKMLHCT*LSRSYNFKFFKRDKL*KMCVFLKC
NICKACSNATYLQLPFYVSSIVSYAIKLFAGL*
IILGKDDQK*CIQQYNKSKPQKNTSGKNRKKVYL
MTCLYEKNSLDMNIWHLQIFILVALLKKKRLYC
CP*MP*SKRVFNRTMLVALCSVWCSFKYLNIYY
SF*LYCVI*KILQKFLVLV*YYLMKVMTYFLYLE
*ACWDRIAYLRGTSQFLHWVLILARALSTISRW
GWPQGCAPRRRWLLAFRPS*WPETFFL*VVWSC
PAGGPLFCHLANNHRNFKNKNIPRFFHFKMLQSP
H*IRYSAVGTFS*GSLQSRLQCDLCFILFL**K
ASGNKPKALTT

Frame 2

PACLLANLGRVGKSSLREPCGSGERFNSEKEKE
SRNK*PWKQLNPSMMEV*QLL*QRASLLMCRLR
LAKIQSLL*LR*QQLQRQMNLQNQKV*LILINV
EKSFHEDPLIGKY*MNCPLMCLVFPRLKKRDQRK
KEHHLVLLPWQYQLAYIRLARGNTLPLVTCQLT
RSELLLLLCHREW*WLHRPEVCTVPSSWQKKQH
ANES*G**KTGKLPKNVDVERKNM*NVWRAELQC
WKSRTRSL*RNLKP*KTFVLPKQITRNI*L*TE
GSMYSCF*RNTIYSWQEWWLLFFVSFIFFFNHL
TFLKCFTVRS*VVAITSNFLKETNCKKCVYS*NA
IFVRLVPMPHTCSSHSMCHQ*CPMQ*NYLQVFK
SF*ERMIKNNASSSTIKVNHKKIPQERIERKSI
**HAYMRRIA*I*IYGICRFLY*LLC*KKKDCIA
VLECHSQREFLIEPCWLHFVVFGAHLNI*TFTT
VFNSTV*YKRSCRSS*CWFNIT**K**HIFYIW
NEPVGIALHTFGVQVSFYTGC*SLHAPFLPSHGG
DGRRAVHPEEDGC*RFGLHNGLRLSFCRWSGAV
RLVAPYFAI*RTTTGILKTKTSQDFFISKCFKV
HIRSDTPLSAHSAEVHYNRDCNVIYVSSCFYNKK
LQGTSPKPSP

Sequence NM_181571

GACCCGCCTGCCTCCTCGCGAACTTGGGACGAGTTGGAAAATCCTCCCTGAGAGAGCCGTGCGGCTCAGGGGAGCGGTTTAACTCGGAAAAGGAAAAGGA
ATCCAGAAGATAAATAAAGAAAACAGGAAAGGAGGAAAGCATTGATTACAAATATCTTAACAATGAGCAAATGTGCAAGGAAAAAATATATTAAGACAAA
TCCAAGACAAATGACCATGGAAACAGTTGAATCCCAGCATGATGGAAGTATAACAGCTTCTTTGACAGAGAGCAAGTCTGCTCATGTGCAGACTCAGACT
GGCCAAAATTCAATCCCTGCTTTAGCTCAGGTAGCAGCAATTGCAGAGACAGATGAATCTGCAGAATCAGAAGGTGTAATTGATTCTCATAAACGTAGAG
AAATCCTTTCACGAAGACCCTCTTATAGGAAAATACTGAATGAACTGTCCTCTGATGTGCCTGGTGTTCCCAAGATTGAAGAAGAGAGATCAGAGGAAGA
AGGAACACCACCTAGTATTGCTACCATGGCAGTACCAACTAGCATATATCAGACTAGCACGGGGCAATACATTGCTATAGCCCAAGGTGGAACAATCCAG
ATTTCTAACCCAGGATCTGATGGTGTTCAGGGACTGCAGGCATTAACAATGACAAATTCAGGAGCTCCTCCACCAGGTGCTACAATTGTACAGTACGCAG
CACAATCAGCTGATGGCACACAGCAGTTCTTTGTCCCAGGCAGCCAGGTTGTTGTTCAAGCTGCCACTGGTGACATGCCAACTTACCAGATCCGAGCTCC
TACTGCTGCTTTGCCACAGGGAGTGGTGATGGCTGCATCGCCCGGAAGTTTGCACAGTCCCCAGCAGCTGGCAGAAGAAGCAACACGCAAACGAGAGCTG
AGGCTAATGAAAAACAGGGAAGCTGCCAAAGAATGTCGACGTCGAAAGAAAGAATATGTAAAATGTCTGGAGAGCCGAGTTGCAGTGCTGGAAGTCCAGA
ACAAGAAGCTTATAGAGGAACTTGAAACCTTGAAAGACATTTGTTCTCCCAAAACAGATTACTAGAAATATTTAACTATGAACTGAAGGCAGCATGTATA
GTTGCTTTTGAAGGAATACAATATATAGCTGGCAAGAATGGTGGCTTCTTTTCTTTGTATCATTCATCTTCTTCTTTAATCACTTAACATTCCTAAAATG
CTTCACTGTACGTAGTTAAGTCGTAGCTATAACTTCAAATTTTTTAAAAGAGACAAACTGTAAAAAATGTGTGTATTCTTAAAATGCAATATTTGTAAGG
CTTGTTCCAATGCCACATACTTGCAGCTCCCATTCTATGTGTCATCAATAGTGTCCTATGCAATAAAATTATTTGCAGGTCTTTAAATCATTTTAGGAAA
GGATGATCAAAAATAATGCATCCAGCAGTACAATAAAAGTAAACCACAAAAAAATACCTCAGGAAAGAATAGAAAGAAAGTCTATCTAATGACATGCCTA
TATGAGAAGAATAGCCTAGATATGAATATATGGCATTTGCAGATTTTTATATTAGTTGCTTTGTTAAAAAAAAAAAGATTGTATTGCTGTCCTTGAATGC
CATAGTCAAAGAGAGTTTTTAATAGAACCATGTTGGTTGCACTTTGTAGTGTTTGGTGCTCATTTAAATATCTGAACATTTACTACAGTTTTTAACTCTA
CTGTGTAATATAAAAGATCTTGCAGAAGTTCTTAGTGTTGGTTTAATATTACCTAATGAAAGTGATGACATATTTTTTATATCTGGAATGAGCCTGTTGG
GATCGCATTGCATACCTTCGGGGTACAAGTCAGTTTCTACACTGGGTGCTGATCCTTGCACGCGCCCTTTCTACCATCTCACGGTGGGGATGGCCGCAGG
GCTGTGCACCCAGAAGAAGATGGCTGTTAGCGTTTCGGCCTTCATAATGGCCTGAGACTTTCTTTCTGTAGGTGGTCTGGAGCTGTCCGGCTGGTGGCCC
CCTATTTTGCCATTTAGCGAACAACCACAGGAATTTTAAAAACAAAAACATCCCAAGATTTTTTCATTTCAAAATGCTTCAAAGTCCACATTAGATCAGA
TACTCCGCTGTCGGCACATTCAGCTGAGGTTCATTACAATCGAGACTGCAATGTGATCTATGTTTCATCTTGTTTTTATAATAAAAAGCTTCAGGGAACA
AGCCCAAAGCCCTCACCACA
  • refseq_CREM.F7 (forward primer)
  • refseq_CREM.R5 (reverse primer)
  • Single exon skipping

Frame 0

DPPASSRTWDELENPP*ESRAAQGSGLTRKRKR
NPEDK*RKQERRKALITNILTMSKCARKKYIKTN
PRQMTMETVESQHDGSITASLTESKSAHVQTQT
GQNSIPALAQVAAIAETDESAESEGVIDSHKRR
EILSRRPSYRKILNELSSDVPGVPKIEEERSEEE
GTPPSIATMAVPTSIYQTSTGQYIAIAQGGTIQ
ISNPGSDGVQGLQALTMTNSGAPPPGATIVQYA
AQSADGTQQFFVPGSQVVVQAATGDMPTYQIRAP
TAALPQGVVMAASPGSLHSPQQLAEEATRKREL
RLMKNREAAKECRRRKKEYVKCLESRVAVLEVQ
NKKLIEELETLKDICSPKTDY*KYLTMN*RQHV*
LLLKEYNI*LARMVASFLCIIHLLL*SLNIPKM
LHCT*LSRSYNFKFFKRDKL*KMCVFLKCNICK
ACSNATYLQLPFYVSSIVSYAIKLFAGL*IILGK
DDQK*CIQQYNKSKPQKNTSGKNRKKVYLMTCL
YEKNSLDMNIWHLQIFILVALLKKKRLYCCP*M
P*SKRVFNRTMLVALCSVWCSFKYLNIYYSF*LY
CVI*KILQKFLVLV*YYLMKVMTYFLYLE*ACW
DRIAYLRGTSQFLHWVLILARALSTISRWGWPQ
GCAPRRRWLLAFRPS*WPETFFL*VVWSCPAGGP
LFCHLANNHRNFKNKNIPRFFHFKMLQSPH*IR
YSAVGTFS*GSLQSRLQCDLCFILFL**KASGN
KPKALTT

Frame 1

TRLPPRELGTSWKILPERAVRLRGAV*LGKGKG
IQKINKENRKGGKH*LQIS*Q*ANVQGKNILRQ
IQDK*PWKQLNPSMMEV*QLL*QRASLLMCRLRL
AKIQSLL*LR*QQLQRQMNLQNQKV*LILINVE
KSFHEDPLIGKY*MNCPLMCLVFPRLKKRDQRK
KEHHLVLLPWQYQLAYIRLARGNTLL*PKVEQSR
FLTQDLMVFRDCRH*Q*QIQELLHQVLQLYSTQ
HNQLMAHSSSLSQAARLLFKLPLVTCQLTRSEL
LLLLCHREW*WLHRPEVCTVPSSWQKKQHANES*
G**KTGKLPKNVDVERKNM*NVWRAELQCWKSR
TRSL*RNLKP*KTFVLPKQITRNI*L*TEGSMY
SCF*RNTIYSWQEWWLLFFVSFIFFFNHLTFLKC
FTVRS*VVAITSNFLKETNCKKCVYS*NAIFVR
LVPMPHTCSSHSMCHQ*CPMQ*NYLQVFKSF*E
RMIKNNASSSTIKVNHKKIPQERIERKSI**HAY
MRRIA*I*IYGICRFLY*LLC*KKKDCIAVLEC
HSQREFLIEPCWLHFVVFGAHLNI*TFTTVFNS
TV*YKRSCRSS*CWFNIT**K**HIFYIWNEPVG
IALHTFGVQVSFYTGC*SLHAPFLPSHGGDGRR
AVHPEEDGC*RFGLHNGLRLSFCRWSGAVRLVA
PYFAI*RTTTGILKTKTSQDFFISKCFKVHIRSD
TPLSAHSAEVHYNRDCNVIYVSSCFYNKKLQGT
SPKPSP

Frame 2

PACLLANLGRVGKSSLREPCGSGERFNSEKEKE
SRR*IKKTGKEESIDYKYLNNEQMCKEKIY*DK
SKTNDHGNS*IPA*WKYNSFFDREQVCSCADSD
WPKFNPCFSSGSSNCRDR*ICRIRRCN*FS*T*R
NPFTKTLL*ENTE*TVL*CAWCSQD*RREIRGR
RNTT*YCYHGSTN*HISD*HGAIHCYSPRWNNP
DF*PRI*WCSGTAGINNDKFRSSSTRCYNCTVRS
TIS*WHTAVLCPRQPGCCSSCHW*HANLPDPSS
YCCFATGSGDGCIARKFAQSPAAGRRSNTQTRA
EANEKQGSCQRMSTSKERICKMSGEPSCSAGSPE
QEAYRGT*NLERHLFSQNRLLEIFNYELKAACI
VAFEGIQYIAGKNGGFFSLYHSSSSLIT*HS*N
ASLYVVKS*L*LQIF*KRQTVKNVCILKMQYL*G
LFQCHILAAPILCVINSVLCNKIICRSLNHFRK
G*SKIMHPAVQ*K*TTKKYLRKE*KESLSNDMP
I*EE*PRYEYMAFADFYISCFVKKKKIVLLSLNA
IVKESF**NHVGCTL*CLVLI*ISEHLLQFLTL
LCNIKDLAEVLSVGLILPNESDDIFFISGMSLL
GSHCIPSGYKSVSTLGADPCTRPFYHLTVGMAAG
LCTQKKMAVSVSAFIMA*DFLSVGGLELSGWWP
PILPFSEQPQEF*KQKHPKIFSFQNASKSTLDQ
ILRCRHIQLRFITIETAM*SMFHLVFIIKSFREQ
AQSPHH

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