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Sequences

Sequence NM_000723

GAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAGCTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGC
GCTGAGGGAGCCCGGCTGGGCCGGGCCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCA
GGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACC
ACATCCAACAGCTTTGTCCGCCAGGGCTCAGCGGAGTCCTACACCAGCCGTCCATCAGACTCTGATGTATCTCTGGAGGAGGACCGGGAAGCCTTAAGGA
AGGAAGCAGAGCGCCAGGCATTAGCGCAGCTCGAGAAGGCCAAGACCAAGCCAGTGGCATTTGCTGTGCGGACAAATGTTGGCTACAATCCGTCTCCAGG
GGATGAGGTGCCTGTGCAGGGAGTGGCCATCACCTTCGAGCCCAAAGACTTCCTGCACATCAAGGAGAAATACAATAATGACTGGTGGATCGGGCGGCTG
GTGAAGGAGGGCTGTGAGGTTGGCTTCATTCCCAGCCCCGTCAAACTGGACAGCCTTCGCCTGCTGCAGGAACAGAAGCTGCGCCAGAACCGCCTCGGCT
CCAGCAAATCAGGCGATAACTCCAGTTCCAGTCTGGGAGATGTGGTGACTGGCACCCGCCGCCCCACACCCCCTGCCAGTGCCAAACAGAAGCAGAAGTC
G
ACAGAGCATGTGCCCCCCTATGACGTGGTGCCTTCCATGAGGCCCATCATCCTGGTGGGACCGTCGCTCAAGGGCTACGAGGTTACAGACATGATGCAG
AAAGCTTTATTTGACTTCTTGAAGCATCGGTTTGATGGCAGGATCTCCATCACTCGTGTGACGGCAGATATTTCCCTGGCTAAGCGCTCAGTTCTCAACA
ACCCCAGCAAACACATCATCATTGAGCGCTCCAACACACGCTCCAGCCTGGCTGAGGTGCAGAGTGAAATCGAGCGAATCTTCGAGCTGGCCCGGACCCT
TCAGTTGGTCGCTCTGGATGCTGACACCATCAATCACCCAGCCCAGCTGTCCAAGACCTCGCTGGCCCCCATCATTGTTTACATCAAGATCACCTCTCCC
AAGGTACTTCAAAGGCTCATCAAGTCCCGAGGAAAGTCTCAGTCCAAACACCTCAATGTCCAAATAGCGGCCTCGGAAAAGCTGGCACAGTGCCCCCCTG
AAATGTTTGACATCATCCTGGATGAGAACCAATTGGAGGATGCCTGCGAGCATCTGGCGGAGTACTTGGAAGCCTATTGGAAGGCCACACACCCGCCCAG
CAGCACGCCACCCAATCCGCTGCTGAACCGCACCATGGCTACCGCAGCCCTGGCTGCCAGCCCTGCCCCTGTCTCCAACCTCCAGGGACCCTACCTTGCT
TCCGGGGACCAGCCACTGGAACGGGCCACCGGGGAGCACGCCAGCATGCACGAGTACCCAGGGGAGCTGGGCCAGCCCCCAGGCCTTTACCCCAGCAGCC
ACCCACCAGGCCGGGCAGGCACGCTACGGGCACTGTCCCGCCAAGACACTTTTGATGCCGACACCCCCGGCAGCCGAAACTCTGCCTACACGGAGCTGGG
AGACTCATGTGTGGACATGGAGACTGACCCCTCAGAGGGGCCAGGGCTTGGAGACCCTGCAGGGGGCGGCACGCCCCCAGCCCGACAGGGATCCTGGGAG
GACGAGGAAGAAGACTATGAGGAAGAGCTGACCGACAACCGGAACCGGGGCCGGAATAAGGCCCGCTACTGCGCTGAGGGTGGGGGTCCAGTTTTGGGGC
GCAACAAGAATGAGCTGGAGGGCTGGGGACGAGGCGTCTACATTCGCTGAGAGGCAGGGGCCACACGGCGGGAGGAAGGGCTCTGAGCCCAGGGGAGGGG
AGGGAGCGAGGGGCTCACACCTGACATGTATTCGCCTCCAGGGGGCGCTGTCTCCCTCCTTTCAGATGCCTTTGCTCAAAGCTTGGGGTTTCTTTGGTGT
TACCATCCCAGCTCCCGGGAGGCCCTTAAGCCCCAGCTGTCGGTTTTTACCTGCCTGTTGTGGATGGATGGGGGATACCCACCTTTCTGAAGTGTCCCCT
TTCTCCCATCTTAAGGGGCTCTCCTCCCTCACCCTCCTAGAGAAAAGGTGCACTTCCTTAACTCTTTCTACTCGGGGCCCTAAGTGACGGTCCTAAGTGG
GATGGCTCTCCTTCTCCCAAGCTGCAGTACTGGGGAAGGGCTGGGCGCTTTTCCTGGAAAGGGAGGCCACAGATTCTTTCCCATGGGGGCTCTCTTCCCC
AGACCCCAGATCCAAGGTCCCTCACCCTGCCTGCCCCTTCCTCCCAGCTTCCTGGCAGCATCGTCTGGTCGGTGAAAGCCATAGCATGGACACCCCATGG
GGAGCTTGTCTTGGGGAGGGTTCTGGGTGGAAGCTGGCAGGCATACAGCACCCTCTACCCTCCGTGGCCATGGCAACGTCCAGGGCCCAGAACCCTGAGG
AGTGAGCGGCCGAGACGCTGCTCCCCACCCCCCACCTCCATGCCTCAGCCTTTGCCTACCCCAGGAATGAGCTTGGCCTCCAACATCCCTTGCCTGCTGC
CATTAGTAGAGGGGGCCCCTCTGCATCTGAGCCCCCCATCCCTGTGCCACCTGGGTGTGGAGCCCATGGAACACTCTGGTCCGCCTCATTTTAAACCAAA
AAACTGCTCCTTCACCCTCACCCTGAGGCCCCAGGGGAGAGGACCCGTGGGATGGTGCCCAGGGGTTGCCTTGGGACCTCGGATCTCCTCTGGGGGGCTT
GGCTGCTGCTGTTGCTGCTCTGTATTTGCCTCTCGTGATTCTGTTTGTTACCCATGTTCACTTCCCCCAGGAGAGGCCTTGGTACCCCCTCTCCCCTGGG
GCATCCCTTTGCCTTGGCATCCCTGTAGCCCAGCAACCCTGCCCCTCCCCAGCATCCCAGCTGGGCCAGAGAGAGCCGAGTGTGCCAACAAGGACTGGGG
CCTGCCCGGCTGCCCGCCTCAGGGATGGGCACCTCATGCCTGTCTCGCCACCTCCTGTGCCAATGTCCCACCCTCCACCTGGGGGTGGGGTGCAGCTTCC
ACTTACTGATTAGAAGACACCACTGCCCTCCCTTCCCCCCTCCCTGTCTGGTGTCCTGTGCCCCCATCTGTCTGTCTATATTTGTCTGTACTCCCCTAGG
AGAAGTATTTTGCCATATATAAAACCACTGTCCTGTCCTTTGTGGCTGCCTCCCAAGCCTGCTTCTTTGTCCTCGCCACATAGTCGTCAGCGTAGGCACC
TGGGAGCTGCTGATATGCACGGGGAGTTGAAAGGGTGGGTGCCTGAAGATGTTGTGCCCTGAGTCATTGACTCAAAAGAAAAGATGATCCTTTGATTTTG
GCCCTCTGATGTATTGTGCCCAAGCCAGGAGCTGCTTGGGCAGTCCCAGCTCCACACTGGCCCTGAGCCCCTTCACTTACCTGTCTCTCCACAAGTAGAG
CCAAAGGCAATGGGAAGCTCAATGTTGCTCAGTGGGTGAGATCCAGACCCACTGGTGCAATGTCTTAAATACACATGACTGTTTTTC
  • refseq_CACNB1.F1 (forward primer)
  • refseq_CACNB1.R1 (reverse primer)
  • Mutually exclusive exon skipping

Frame 0

EGRQEGGSRRPSWVAGPGAGCAALLSAPTASPM
R*GSPAGPGRRREGRLLSMVQKTSMSRGPYPPSQ
EIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDT
TSNSFVRQGSAESYTSRPSDSDVSLEEDREALR
KEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPG
DEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRL
VKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG
SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKS
TEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQ
KALFDFLKHRFDGRISITRVTADISLAKRSVLN
NPSKHIIIERSNTRSSLAEVQSEIERIFELARTL
QLVALDADTINHPAQLSKTSLAPIIVYIKITSP
KVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP
EMFDIILDENQLEDACEHLAEYLEAYWKATHPPS
STPPNPLLNRTMATAALAASPAPVSNLQGPYLA
SGDQPLERATGEHASMHEYPGELGQPPGLYPSS
HPPGRAGTLRALSRQDTFDADTPGSRNSAYTELG
DSCVDMETDPSEGPGLGDPAGGGTPPARQGSWE
DEEEDYEEELTDNRNRGRNKARYCAEGGGPVLG
RNKNELEGWGRGVYIR*EAGATRREEGL*AQGRG
GSEGLTPDMYSPPGGAVSLLSDAFAQSLGFLWC
YHPSSREALKPQLSVFTCLLWMDGGYPPF*SVP
FLPS*GALLPHPPREKVHFLNSFYSGP*VTVLSG
MALLLPSCSTGEGLGAFPGKGGHRFFPMGALFP
RPQIQGPSPCLPLPPSFLAASSGR*KP*HGHPM
GSLSWGGFWVEAGRHTAPSTLRGHGNVQGPEP*G
VSGRDAAPHPPPPCLSLCLPQE*AWPPTSLACC
H**RGPLCI*APHPCATWVWSPWNTLVRLILNQ
KTAPSPSP*GPRGEDPWDGAQGLPWDLGSPLGGL
AAAVAALYLPLVILFVTHVHFPQERPWYPLSPG
ASLCLGIPVAQQPCPSPASQLGQREPSVPTRTG
ACPAARLRDGHLMPVSPPPVPMSHPPPGGGVQLP
LTD*KTPLPSLPPSLSGVLCPHLSVYICLYSPR
RSILPYIKPLSCPLWLPPKPASLSSPHSRQRRH
LGAADMHGELKGWVPEDVVP*VIDSKEKMIL*FW
PSDVLCPSQELLGQSQLHTGPEPLHLPVSPQVE
PKAMGSSMLLSG*DPDPLVQCLKYT*LFF

Frame 1

REGRKEAAEGRAGWLDRVLAAPRCFRLPRPLPC
AEGARLGRAGGGRGGSSPWSRRPACPGALTHPP
RRSPWRSSTPARRANTARGKGDSNGQMGARPRIP
HPTALSARAQRSPTPAVHQTLMYLWRRTGKP*G
RKQSARH*RSSRRPRPSQWHLLCGQMLATIRLQ
GMRCLCREWPSPSSPKTSCTSRRNTIMTGGSGGW
*RRAVRLASFPAPSNWTAFACCRNRSCARTASA
PANQAITPVPVWEMW*LAPAAPHPLPVPNRSRS
R
QSMCPPMTWCLP*GPSSWWDRRSRATRLQT*CR
KLYLTS*SIGLMAGSPSLV*RQIFPWLSAQFST
TPANTSSLSAPTHAPAWLRCRVKSSESSSWPGP
FSWSLWMLTPSITQPSCPRPRWPPSLFTSRSPLP
RYFKGSSSPEESLSPNTSMSK*RPRKSWHSAPL
KCLTSSWMRTNWRMPASIWRSTWKPIGRPHTRP
AARHPIRC*TAPWLPQPWLPALPLSPTSRDPTLL
PGTSHWNGPPGSTPACTSTQGSWASPQAFTPAA
THQAGQARYGHCPAKTLLMPTPPAAETLPTRSW
ETHVWTWRLTPQRGQGLETLQGAARPQPDRDPGR
TRKKTMRKS*PTTGTGAGIRPATALRVGVQFWG
ATRMSWRAGDEASTFAERQGPHGGRKGSEPRGG
EGARGSHLTCIRLQGALSPSFQMPLLKAWGFFGV
TIPAPGRPLSPSCRFLPACCGWMGDTHLSEVSP
FSHLKGLSSLTLLEKRCTSLTLSTRGPK*RS*V
GWLSFSQAAVLGKGWALFLEREATDSFPWGLSSP
DPRSKVPHPACPFLPASWQHRLVGESHSMDTPW
GACLGEGSGWKLAGIQHPLPSVAMATSRAQNPE
E*AAETLLPTPHLHASAFAYPRNELGLQHPLPAA
ISRGGPSASEPPIPVPPGCGAHGTLWSASF*TK
KLLLHPHPEAPGERTRGMVPRGCLGTSDLLWGA
WLLLLLLCICLS*FCLLPMFTSPRRGLGTPSPLG
HPFALASL*PSNPAPPQHPSWARESRVCQQGLG
PARLPASGMGTSCLSRHLLCQCPTLHLGVGCSF
HLLIRRHHCPPFPPPCLVSCAPICLSIFVCTPLG
EVFCHI*NHCPVLCGCLPSLLLCPRHIVVSVGT
WELLICTGS*KGGCLKMLCPESLTQKKR*SFDF
GPLMYCAQARSCLGSPSSTLALSPFTYLSLHK*S
QRQWEAQCCSVGEIQTHWCNVLNTHDCF

Frame 2

GKAGRRQPKAELGGWTGCWLRRAAFGSHGLSHA
LREPGWAGPAAGGEAPLHGPEDQHVPGPLPTLP
GDPHGGLRPQPAGQIQQEERAIQTVRWEHVLGY
HIQQLCPPGLSGVLHQPSIRL*CISGGGPGSLKE
GSRAPGISAAREGQDQASGICCADKCWLQSVSR
G*GACAGSGHHLRAQRLPAHQGEIQ**LVDRAA
GEGGL*GWLHSQPRQTGQPSPAAGTEAAPEPPRL
QQIRR*LQFQSGRCGDWHPPPHTPCQCQTEAEV
DRACAPL*RGAFHEAHHPGGTVAQGLRGYRHDA
ESFI*LLEASV*WQDLHHSCDGRYFPG*ALSSQQ
PQQTHHH*ALQHTLQPG*GAE*NRANLRAGPDP
SVGRSGC*HHQSPSPAVQDLAGPHHCLHQDHLS
QGTSKAHQVPRKVSVQTPQCPNSGLGKAGTVPP*
NV*HHPG*EPIGGCLRASGGVLGSLLEGHTPAQ
QHATQSAAEPHHGYRSPGCQPCPCLQPPGTLPC
FRGPATGTGHRGARQHARVPRGAGPAPRPLPQQP
PTRPGRHATGTVPPRHF*CRHPRQPKLCLHGAG
RLMCGHGD*PLRGARAWRPCRGRHAPSPTGILG
GRGRRL*GRADRQPEPGPE*GPLLR*GWGSSFGA
QQE*AGGLGTRRLHSLRGRGHTAGGRALSPGEG
RERGAHT*HVFASRGRCLPPFRCLCSKLGVSLV
LPSQLPGGP*APAVGFYLPVVDGWGIPTFLKCPL
SPILRGSPPSPS*RKGALP*LFLLGALSDGPKW
DGSPSPKLQYWGRAGRFSWKGRPQILSHGGSLP
QTPDPRSLTLPAPSSQLPGSIVWSVKAIAWTPHG
ELVLGRVLGGSWQAYSTLYPPWPWQRPGPRTLR
SERPRRCSPPPTSMPQPLPTPGMSLASNIPCLL
PLVEGAPLHLSPPSLCHLGVEPMEHSGPPHFKPK
NCSFTLTLRPQGRGPVGWCPGVALGPRISSGGL
GCCCCCSVFASRDSVCYPCSLPPGEALVPPLPW
GIPLPWHPCSPATLPLPSIPAGPERAECANKDWG
LPGCPPQGWAPHACLATSCANVPPSTWGWGAAS
TY*LEDTTALPSPLPVWCPVPPSVCLYLSVLP*
EKYFAIYKTTVLSFVAASQACFFVLAT*SSA*AP
GSC*YARGVERVGA*RCCALSH*LKRKDDPLIL
AL*CIVPKPGAAWAVPAPHWP*APSLTCLSTSR
AKGNGKLNVAQWVRSRPTGAMS*IHMTVF

Sequence NM_199248

GAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAGCTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGC
GCTGAGGGAGCCCGGCTGGGCCGGGCCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCA
GGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACC
ACATCCAACAGCTTTGTCCGCCAGGGCTCAGCGGAGTCCTACACCAGCCGTCCATCAGACTCTGATGTATCTCTGGAGGAGGACCGGGAAGCCTTAAGGA
AGGAAGCAGAGCGCCAGGCATTAGCGCAGCTCGAGAAGGCCAAGACCAAGCCAGTGGCATTTGCTGTGCGGACAAATGTTGGCTACAATCCGTCTCCAGG
GGATGAGGTGCCTGTGCAGGGAGTGGCCATCACCTTCGAGCCCAAAGACTTCCTGCACATCAAGGAGAAATACAATAATGACTGGTGGATCGGGCGGCTG
GTGAAGGAGGGCTGTGAGGTTGGCTTCATTCCCAGCCCCGTCAAACTGGACAGCCTTCGCCTGCTGCAGGAACAGAAGCTGCGCCAGAACCGCCTCGGCT
CCAGCAAATCAGGCGATAACTCCAGTTCCAGTCTGGGAGATGTGGTGACTGGCACCCGCCGCCCCACACCCCCTGCCAGTGCCAAACAGAAGCAGAAGTC
G
ACAGAGCATGTGCCCCCCTATGACGTGGTGCCTTCCATGAGGCCCATCATCCTGGTGGGACCGTCGCTCAAGGGCTACGAGGTTACAGACATGATGCAG
AAAGCTTTATTTGACTTCTTGAAGCATCGGTTTGATGGCAGGATCTCCATCACTCGTGTGACGGCAGATATTTCCCTGGCTAAGCGCTCAGTTCTCAACA
ACCCCAGCAAACACATCATCATTGAGCGCTCCAACACACGCTCCAGCCTGGCTGAGGTGCAGAGTGAAATCGAGCGAATCTTCGAGCTGGCCCGGACCCT
TCAGTTGGTCGCTCTGGATGCTGACACCATCAATCACCCAGCCCAGCTGTCCAAGACCTCGCTGGCCCCCATCATTGTTTACATCAAGATCACCTCTCCC
AAGGTACTTCAAAGGCTCATCAAGTCCCGAGGAAAGTCTCAGTCCAAACACCTCAATGTCCAAATAGCGGCCTCGGAAAAGCTGGCACAGTGCCCCCCTG
AAATGTTTGACATCATCCTGGATGAGAACCAATTGGAGGATGCCTGCGAGCATCTGGCGGAGTACTTGGAAGCCTATTGGAAGGCCACACACCCGCCCAG
CAGCACGCCACCCAATCCGCTGCTGAACCGCACCATGGCTACCGCAGCCCTGGCTGCCAGCCCTGCCCCTGTCTCCAACCTCCAGGTACAGGTGCTCACC
TCGCTCAGGAGAAACCTCGGCTTCTGGGGCGGGCTGGAGTCCTCACAGCGGGGCAGTGTGGTGCCCCAGGAGCAGGAACATGCCATGTAGTGGGCGCCCT
GCCCGTCTTCCCTCCTGCTCTGGGGTCGGAACTGGAGTGCAGGGAACATGGAGGAGGAAGGGAAGAGCTTTATTTTGTAAAAAAATAAGATGAGCGGCA
  • refseq_CACNB1.F1 (forward primer)
  • refseq_CACNB1.R1 (reverse primer)
  • Mutually exclusive exon skipping

Frame 0

EGRQEGGSRRPSWVAGPGAGCAALLSAPTASPM
R*GSPAGPGRRREGRLLSMVQKTSMSRGPYPPSQ
EIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDT
TSNSFVRQGSAESYTSRPSDSDVSLEEDREALR
KEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPG
DEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRL
VKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG
SSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKS
TEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQ
KALFDFLKHRFDGRISITRVTADISLAKRSVLN
NPSKHIIIERSNTRSSLAEVQSEIERIFELARTL
QLVALDADTINHPAQLSKTSLAPIIVYIKITSP
KVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPP
EMFDIILDENQLEDACEHLAEYLEAYWKATHPPS
STPPNPLLNRTMATAALAASPAPVSNLQVQVLT
SLRRNLGFWGGLESSQRGSVVPQEQEHAM*WAP
CPSSLLLWGRNWSAGNMEEEGKSFIL*KNKMSG

Frame 1

REGRKEAAEGRAGWLDRVLAAPRCFRLPRPLPC
AEGARLGRAGGGRGGSSPWSRRPACPGALTHPP
RRSPWRSSTPARRANTARGKGDSNGQMGARPRIP
HPTALSARAQRSPTPAVHQTLMYLWRRTGKP*G
RKQSARH*RSSRRPRPSQWHLLCGQMLATIRLQ
GMRCLCREWPSPSSPKTSCTSRRNTIMTGGSGGW
*RRAVRLASFPAPSNWTAFACCRNRSCARTASA
PANQAITPVPVWEMW*LAPAAPHPLPVPNRSRS
R
QSMCPPMTWCLP*GPSSWWDRRSRATRLQT*CR
KLYLTS*SIGLMAGSPSLV*RQIFPWLSAQFST
TPANTSSLSAPTHAPAWLRCRVKSSESSSWPGP
FSWSLWMLTPSITQPSCPRPRWPPSLFTSRSPLP
RYFKGSSSPEESLSPNTSMSK*RPRKSWHSAPL
KCLTSSWMRTNWRMPASIWRSTWKPIGRPHTRP
AARHPIRC*TAPWLPQPWLPALPLSPTSRYRCSP
RSGETSASGAGWSPHSGAVWCPRSRNMPCSGRP
ARLPSCSGVGTGVQGTWRRKGRALFCKKIR*AA

Frame 2

GKAGRRQPKAELGGWTGCWLRRAAFGSHGLSHA
LREPGWAGPAAGGEAPLHGPEDQHVPGPLPTLP
GDPHGGLRPQPAGQIQQEERAIQTVRWEHVLGY
HIQQLCPPGLSGVLHQPSIRL*CISGGGPGSLKE
GSRAPGISAAREGQDQASGICCADKCWLQSVSR
G*GACAGSGHHLRAQRLPAHQGEIQ**LVDRAA
GEGGL*GWLHSQPRQTGQPSPAAGTEAAPEPPRL
QQIRR*LQFQSGRCGDWHPPPHTPCQCQTEAEV
DRACAPL*RGAFHEAHHPGGTVAQGLRGYRHDA
ESFI*LLEASV*WQDLHHSCDGRYFPG*ALSSQQ
PQQTHHH*ALQHTLQPG*GAE*NRANLRAGPDP
SVGRSGC*HHQSPSPAVQDLAGPHHCLHQDHLS
QGTSKAHQVPRKVSVQTPQCPNSGLGKAGTVPP*
NV*HHPG*EPIGGCLRASGGVLGSLLEGHTPAQ
QHATQSAAEPHHGYRSPGCQPCPCLQPPGTGAH
LAQEKPRLLGRAGVLTAGQCGAPGAGTCHVVGAL
PVFPPALGSELECREHGGGREELYFVKK*DER

Sequence NM_199247

GAGGGAAGGCAGGAAGGAGGCAGCCGAAGGCCGAGCTGGGTGGCTGGACCGGGTGCTGGCTGCGCCGCGCTGCTTTCGGCTCCCACGGCCTCTCCCATGC
GCTGAGGGAGCCCGGCTGGGCCGGGCCGGCGGCGGGAGGGGAGGCTCCTCTCCATGGTCCAGAAGACCAGCATGTCCCGGGGCCCTTACCCACCCTCCCA
GGAGATCCCCATGGAGGTCTTCGACCCCAGCCCGCAGGGCAAATACAGCAAGAGGAAAGGGCGATTCAAACGGTCAGATGGGAGCACGTCCTCGGATACC
ACATCCAACAGCTTTGTCCGCCAGGGCTCAGCGGAGTCCTACACCAGCCGTCCATCAGACTCTGATGTATCTCTGGAGGAGGACCGGGAAGCCTTAAGGA
AGGAAGCAGAGCGCCAGGCATTAGCGCAGCTCGAGAAGGCCAAGACCAAGCCAGTGGCATTTGCTGTGCGGACAAATGTTGGCTACAATCCGTCTCCAGG
GGATGAGGTGCCTGTGCAGGGAGTGGCCATCACCTTCGAGCCCAAAGACTTCCTGCACATCAAGGAGAAATACAATAATGACTGGTGGATCGGGCGGCTG
GTGAAGGAGGGCTGTGAGGTTGGCTTCATTCCCAGCCCCGTCAAACTGGACAGCCTTCGCCTGCTGCAGGAACAGAAGCTGCGCCAGAACCGCCTCGGCT
CCAGCAAATCAGGCGATAACTCCAGTTCCAGTCTGGGAGATGTGGTGACTGGCACCCGCCGCCCCACACCCCCTGCCAGTGGTAATGAAATGACTAACTT
AGCCTTTGAACTAGACCCCCTAGAGTTAGAGGAGGAAGAGGCTGAGCTTGGTGAGCAGAGTGGCTCTGCCAAGACTAGTGTTAGCAGTGTCACCACCCCG
CCACCCCATGGCAAACGCATCCCCTTCTTTAAGAAG
ACAGAGCATGTGCCCCCCTATGACGTGGTGCCTTCCATGAGGCCCATCATCCTGGTGGGACCGT
CGCTCAAGGGCTACGAGGTTACAGACATGATGCAGAAAGCTTTATTTGACTTCTTGAAGCATCGGTTTGATGGCAGGATCTCCATCACTCGTGTGACGGC
AGATATTTCCCTGGCTAAGCGCTCAGTTCTCAACAACCCCAGCAAACACATCATCATTGAGCGCTCCAACACACGCTCCAGCCTGGCTGAGGTGCAGAGT
GAAATCGAGCGAATCTTCGAGCTGGCCCGGACCCTTCAGTTGGTCGCTCTGGATGCTGACACCATCAATCACCCAGCCCAGCTGTCCAAGACCTCGCTGG
CCCCCATCATTGTTTACATCAAGATCACCTCTCCCAAGGTACTTCAAAGGCTCATCAAGTCCCGAGGAAAGTCTCAGTCCAAACACCTCAATGTCCAAAT
AGCGGCCTCGGAAAAGCTGGCACAGTGCCCCCCTGAAATGTTTGACATCATCCTGGATGAGAACCAATTGGAGGATGCCTGCGAGCATCTGGCGGAGTAC
TTGGAAGCCTATTGGAAGGCCACACACCCGCCCAGCAGCACGCCACCCAATCCGCTGCTGAACCGCACCATGGCTACCGCAGCCCTGGCTGCCAGCCCTG
CCCCTGTCTCCAACCTCCAGGTACAGGTGCTCACCTCGCTCAGGAGAAACCTCGGCTTCTGGGGCGGGCTGGAGTCCTCACAGCGGGGCAGTGTGGTGCC
CCAGGAGCAGGAACATGCCATGTAGTGGGCGCCCTGCCCGTCTTCCCTCCTGCTCTGGGGTCGGAACTGGAGTGCAGGGAACATGGAGGAGGAAGGGAAG
AGCTTTATTTTGTAAAAAAATAAGATGAGCGGCA
  • refseq_CACNB1.F1 (forward primer)
  • refseq_CACNB1.R1 (reverse primer)
  • Mutually exclusive exon skipping

Frame 0

EGRQEGGSRRPSWVAGPGAGCAALLSAPTASPM
R*GSPAGPGRRREGRLLSMVQKTSMSRGPYPPSQ
EIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDT
TSNSFVRQGSAESYTSRPSDSDVSLEEDREALR
KEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPG
DEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRL
VKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLG
SSKSGDNSSSSLGDVVTGTRRPTPPASGNEMTNL
AFELDPLELEEEEAELGEQSGSAKTSVSSVTTP
PPHGKRIPFFKK
TEHVPPYDVVPSMRPIILVGP
SLKGYEVTDMMQKALFDFLKHRFDGRISITRVTA
DISLAKRSVLNNPSKHIIIERSNTRSSLAEVQS
EIERIFELARTLQLVALDADTINHPAQLSKTSL
APIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQI
AASEKLAQCPPEMFDIILDENQLEDACEHLAEY
LEAYWKATHPPSSTPPNPLLNRTMATAALAASP
APVSNLQVQVLTSLRRNLGFWGGLESSQRGSVVP
QEQEHAM*WAPCPSSLLLWGRNWSAGNMEEEGK
SFIL*KNKMSG

Frame 1

REGRKEAAEGRAGWLDRVLAAPRCFRLPRPLPC
AEGARLGRAGGGRGGSSPWSRRPACPGALTHPP
RRSPWRSSTPARRANTARGKGDSNGQMGARPRIP
HPTALSARAQRSPTPAVHQTLMYLWRRTGKP*G
RKQSARH*RSSRRPRPSQWHLLCGQMLATIRLQ
GMRCLCREWPSPSSPKTSCTSRRNTIMTGGSGGW
*RRAVRLASFPAPSNWTAFACCRNRSCARTASA
PANQAITPVPVWEMW*LAPAAPHPLPVVMK*LT
*PLN*TP*S*RRKRLSLVSRVALPRLVLAVSPPR
HPMANASPSLRR
QSMCPPMTWCLP*GPSSWWDR
RSRATRLQT*CRKLYLTS*SIGLMAGSPSLV*R
QIFPWLSAQFSTTPANTSSLSAPTHAPAWLRCRV
KSSESSSWPGPFSWSLWMLTPSITQPSCPRPRW
PPSLFTSRSPLPRYFKGSSSPEESLSPNTSMSK
*RPRKSWHSAPLKCLTSSWMRTNWRMPASIWRST
WKPIGRPHTRPAARHPIRC*TAPWLPQPWLPAL
PLSPTSRYRCSPRSGETSASGAGWSPHSGAVWC
PRSRNMPCSGRPARLPSCSGVGTGVQGTWRRKGR
ALFCKKIR*AA

Frame 2

GKAGRRQPKAELGGWTGCWLRRAAFGSHGLSHA
LREPGWAGPAAGGEAPLHGPEDQHVPGPLPTLP
GDPHGGLRPQPAGQIQQEERAIQTVRWEHVLGY
HIQQLCPPGLSGVLHQPSIRL*CISGGGPGSLKE
GSRAPGISAAREGQDQASGICCADKCWLQSVSR
G*GACAGSGHHLRAQRLPAHQGEIQ**LVDRAA
GEGGL*GWLHSQPRQTGQPSPAAGTEAAPEPPRL
QQIRR*LQFQSGRCGDWHPPPHTPCQW**ND*L
SL*TRPPRVRGGRG*AW*AEWLCQD*C*QCHHP
ATPWQTHPLL*E
DRACAPL*RGAFHEAHHPGGTV
AQGLRGYRHDAESFI*LLEASV*WQDLHHSCDG
RYFPG*ALSSQQPQQTHHH*ALQHTLQPG*GAE
*NRANLRAGPDPSVGRSGC*HHQSPSPAVQDLAG
PHHCLHQDHLSQGTSKAHQVPRKVSVQTPQCPN
SGLGKAGTVPP*NV*HHPG*EPIGGCLRASGGV
LGSLLEGHTPAQQHATQSAAEPHHGYRSPGCQPC
PCLQPPGTGAHLAQEKPRLLGRAGVLTAGQCGA
PGAGTCHVVGALPVFPPALGSELECREHGGGRE
ELYFVKK*DER

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