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Sequences

Sequence NM_138278

AGCTACAACAGCTGAGACAGAAAAGAGGTAAGGAAGTGTTGGGGGCTGGGACAACCAGCTCCCCAACAACTCCTAGGTGTTTAAAGAAGGAGGCAGGAAG ACTTGTGAAGATGGGAACTATACAAGAGGCAGGAAAAAAGACAGATGTTGGGTGGAGCAACTGCTACAGAGGTAAATATGATTAACTTTACATTCCATCT TTCGTCTGCTCCCAAACTTAACAGCAGGTAATCTGCTTCTAGCAAGTGGTGAAGGTAAGAGAAGCATCTGTATAGGAGGCAAGAGATCTGAGTCCTTTTG AAGGCCTATCCTCTGCTCTGTATCTCAATTACTGTTCTTCATTTCAATTATTCTTACCTACTATTCAGTTCCCTTGATCTTTTCTTCTTGGGGGCTGTCT TAGGGTCAGGGAGATTGCAGAAGCACCAGAACTAGGAGCAGCCCTGAGACATGGGGAGTTGGAGCTGAAGGAGGAATGGCAGGATGAAGAATTCCCTAGA TTGCTTCCTGAGGAGGCTGGCACTTCTGAAGATCCTGAAGACCCTAAAGGAGATTCACAGGCAGCTGCAGGTACCCCCAGCACTTTAGCCCTGTGTGGCC AGCGCCCCATGCGCAAGCGTCTTTCTGCCCCAGAGTTGCGGCTGAGTCTGACTAAGGGGCCTGGAAATGATGGAGCTTCACCCACCCAGTCTGCACCTTC CTCTCCTGATGGCAGTTCTGACCTGGAGATAGACGAATTGGAGACACCTTCAGACTCGGAGCAGCTGGACAGTGGACATGAATTTGAATGGGAAGATGAA CTACCCCGGGCAGAGGGTCTGGGCACCAGTGAGACAGCTGAAAGGCTGGGCCGAGGTTGTATGTGGGATGTGACTGGAGAAGATGGACATCACTGGAGGG TGTTCCGAATGGGACCACGGGAGCAGCGCGTAGACATGACTGTCATTGAGCCCTATAAGAAAGTCCTGTCTCATGGAGGTTACCACGGTGATGGCCTCAA TGCTGTCATCCTTTTTGCTTCCTGTTATCTACCCAGAAGCAGCATCCCCAACTACACCTATGTCATGGAACACTTGTTTAGGTATATGGTGGGAACTCTG GAGCTGCTAGTAGCTGAAAATTACCTGCTTGTTCATTTGAGTGGAGGCACAAGCAGGGCCCAAGTTCCACCTCTAAGCTGGATACGTCAGTGTTACCGTA CCCTGGATCGGCGGCTACGGAAAAACCTGCGAGCCCTGGTGGTTGTCCATGCTACATGGTATGTGAAAGCATTTCTGGCACTGCTTCGGCCCTTCATCAG TTCCAAATTCACACGAAAAATCCGTTTTCTGGACAGCCTGGGGGAGCTGGCCCAACTCATATCCCTGGATCAAGTCCACATCCCTGAAGCTGTCAGACAG CTGGACCGGGATCTCCATGGCTCAGGAGGGACATAGCACAGGACTGGATAAAAGGCCTTAGAACCAGTTAGTGATCTGCCTACACCTGAATCCCTGAAAC ATCTGAACTGTTTTGTAAATCATCTTATCCCCAACCTCAGTACCACCGGATCTTCACTTCTCAGTGGGATTTTGTCCTTTGCATGACCCTACTTTCAGCA GGGCTTTGAGGCTGGGAAACTGATCTGCTGGGTGACTTTCATTCCAGTTGCTGGGACGGAAGGCTGAATGTAGGGTCATTTTGTATGGGATATGCAGAGC TCTGGGTTTTTTTGTTTTTTGTTTTTTGAGACGGAGTCTCGCTCTGTCGCCAGGCTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAACCTCCGCCTCC CGGTTCAAGCCATTCTTCTGCCTCAGCCTCAGCGAGTAGCTGAGACTACCGGCGCACGCCACCACGCCCAGCTAATTGTTTTGTATTTTTAGTAGAGACG GGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCTGCCCGCCTCGGCCTCCCAAAGTGCCGAGATTACAGGTGTGAGCCACCGC GCTCGGCCAGAGCTCTGGGTTTTAATCCTACTTTAGCTGTAGAACCTTGGGCAAATAACTTCATCTTTTTGGGTCCTAATTTTCCTCCTGTCTAACTGGA GGGACTGTGATCCTTCCACCTTGGATGGAAGAGGCTTACCTGACAGCCAGCCTGCCTGCTGGGAGCCAGGAGAGTCAGCTCATTAAATCTTGAAGAACCG CTGTATGCCCTTTTTCCTTCTAAGTCATGTCTGCTGCCTGTGAGCCTGGGAAGGAGTGCTTTCAAAACCTGTATTTTTGCCCTCTTTAGTAAATTTAGAA CTGTAGAGGCTAATAAACTGCGATGAGACATTTAA

refseq_BNIPL.F1 (forward primer)
refseq_BNIPL.R1 (reverse primer)
Single exon skipping

Frame 0

SYNS*DRKEVRKCWGLGQPAPQQLLGV*RRRQE DL*RWELYKRQEKRQMLGGATATEVNMINFTFHL SSAPKLNSR*SASSKW*R*EKHLYRRQEI*VLL KAYPLLCISITVLHFNYSYLLFSSLDLFFLGAV LGSGRLQKHQN*EQP*DMGSWS*RRNGRMKNSLD CFLRRLALLKILKTLKEIHRQLQVPPAL*PCVA SAPCASVFLPQSCG*V*LRGLEMMELHPPSLHL PLLMAVLTWR*TNWRHLQTRSSWTVDMNLNGKMN YPGQRVWAPVRQLKGWAEVVCGM*LEKMDITGG CSEWDHGSSA*T*LSLSPIRKSCLMEVTTVMAS MLSSFLLPVIYPEAASPTTPMSWNTCLGIWWELW SC**LKITCLFI*VEAQAGPKFHL*AGYVSVTV PWIGGYGKTCEPWWLSMLHGM*KHFWHCFGPSS VPNSHEKSVFWTAWGSWPNSYPWIKSTSLKLSDS WTGISMAQEGHSTGLDKRP*NQLVICLHLNP*N I*TVL*IILSPTSVPPDLHFSVGFCPLHDPTFS RALRLGN*SAG*LSFQLLGRKAECRVILYGICRA LGFFVFCFLRRSLALSPGWSAVVRSRLTATSAS RFKPFFCLSLSE*LRLPAHATTPS*LFCIFSRD GVSPCWPGWSRSLDLVICPPRPPKVPRLQV*ATA LGQSSGF*SYFSCRTLGK*LHLFGS*FSSCLTG GTVILPPWMEEAYLTASLPAGSQESQLIKS*RT AVCPFSF*VMSAACEPGKECFQNLYFCPL**I*N CRG**TAMRHL

Frame 1

ATTAETEKR*GSVGGWDNQLPNNS*VFKEGGRK TCEDGNYTRGRKKDRCWVEQLLQR*I*LTLHSI FRLLPNLTAGNLLLASGEGKRSICIGGKRSESF* RPILCSVSQLLFFISIILTYYSVPLIFSSWGLS *GQGDCRSTRTRSSPETWGVGAEGGMAG*RIP* IAS*GGWHF*RS*RP*RRFTGSCRYPQHFSPVWP APHAQASFCPRVAAESD*GAWK*WSFTHPVCTF LS*WQF*PGDRRIGDTFRLGAAGQWT*I*MGR* TTPGRGSGHQ*DS*KAGPRLYVGCDWRRWTSLEG VPNGTTGAARRHDCH*AL*ESPVSWRLPR*WPQ CCHPFCFLLSTQKQHPQLHLCHGTLV*VYGGNS GAASS*KLPACSFEWRHKQGPSSTSKLDTSVLPY PGSAATEKPASPGGCPCYMVCESISGTASALHQ FQIHTKNPFSGQPGGAGPTHIPGSSPHP*SCQT AGPGSPWLRRDIAQDWIKGLRTS**SAYT*IPET SELFCKSSYPQPQYHRIFTSQWDFVLCMTLLSA GL*GWETDLLGDFHSSCWDGRLNVGSFCMGYAE LWVFLFFVF*DGVSLCRQAGVQWCDLGSLQPPPP GSSHSSASASASS*DYRRTPPRPANCFVFLVET GFHHVGQDGLDLLTS*SARLGLPKCRDYRCEPP RSARALGFNPTLAVEPWANNFIFLGPNFPPV*LE GL*SFHLGWKRLT*QPACLLGARRVSSLNLEEP LYALFPSKSCLLPVSLGRSAFKTCIFALFSKFR TVEANKLR*DI*

Frame 2

LQQLRQKRGKEVLGAGTTSSPTTPRCLKKEAGR LVKMGTIQEAGKKTDVGWSNCYRGKYD*LYIPS FVCSQT*QQVICF*QVVKVREASV*EARDLSPF EGLSSALYLNYCSSFQLFLPTIQFP*SFLLGGCL RVREIAEAPELGAALRHGELELKEEWQDEEFPR LLPEEAGTSEDPEDPKGDSQAAAGTPSTLALCG QRPMRKRLSAPELRLSLTKGPGNDGASPTQSAPS SPDGSSDLEIDELETPSDSEQLDSGHEFEWEDE LPRAEGLGTSETAERLGRGCMWDVTGEDGHHWR VFRMGPREQRVDMTVIEPYKKVLSHGGYHGDGLN AVILFASCYLPRSSIPNYTYVMEHLFRYMVGTL ELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYR TLDRRLRKNLRALVVVHATWYVKAFLALLRPFIS SKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQ LDRDLHGSGGT*HRTG*KALEPVSDLPTPESLK HLNCFVNHLIPNLSTTGSSLLSGILSFA*PYFQQ GFEAGKLICWVTFIPVAGTEG*M*GHFVWDMQS SGFFCFLFFETESRSVARLECSGAISAHCNLRL PVQAILLPQPQRVAETTGARHHAQLIVLYF**RR GFTMLARMVSIS*PRDLPASASQSAEITGVSHR ARPELWVLILL*L*NLGQITSSFWVLIFLLSNW RDCDPSTLDGRGLPDSQPACWEPGESAH*ILKNR CMPFFLLSHVCCL*AWEGVLSKPVFLPSLVNLE L*RLINCDETF

Sequence NM_138279

ATGCGCAAGCGTCTTTCTGCCCCAGAGTTGCGGCTGAGTCTGACTAAGGGGCCTGGAAATGATGGAGCTTCACCCACCCAGTCTGCACCTTCCTCTCCTG ATGGCAGTTCTGACCTGGAGATAGACGAATTGGAGACACCTTCAGACTCGGAGCAGCTGGACAGTGGACATGAATTTGAATGGGAAGATGAACTACCCCG GGCAGAGGGTCTGGGCACCAGTGAGACAGCTGAAAGGCTGGGCCGAGGTTGTATGTGGGATGTGACTGGAGAAGATGGACATCACTGGAGGGTGTTCCGA ATGGGACCACGGGAGCAGCGCGTAGACATGACTGTCATTGAGCCCTATAAGAAAGTCCTGTCTCATGGAGGTTACCACGGTGATGGCCTCAATGCTGTCA TCCTTTTTGCTTCCTGTTATCTACCCAGAAGCAGCATCCCCAACTACACCTATGTCATGGAACACTTGTTTAGGTATATGGTGGGAACTCTGGAGCTGCT AGTAGCTGAAAATTACCTGCTTGTTCATTTGAGTGGAGGCACAAGCAGGGCCCAAGTTCCACCTCTAAGCTGGATACGTCAGTGTTACCGTACCCTGGAT CGGCGAGTTTTATAAGTAATCTTGGTCATGGAGCGATGTAGAAGCATGCAAAAGGAACTTACGCGAGGGTAGAGCACAAGATGGAAATGGAGCAGAAAAA GACCAGGTGGTCGGGCGCGGTGGCTCACGTCTGTAATCCCAGCACTTTGGAAGGCCGAGGCTACGGAAAAACCTGCGAGCCCTGGTGGTTGTCCATGCTA CATGGTATGTGAAAGCATTTCTGGCACTGCTTCGGCCCTTCATCAGTTCCAAATTCACACGAAAAATCCGTTTTCTGGACAGCCTGGGGGAGCTGGCCCA ACTCATATCCCTGGATCAAGTCCACATCCCTGAAGCTGTCAGACAGCTGGACCGGGATCTCCATGGCTCAGGAGGGACATAGCACAGGACTGGATAAAAG GCCTTAGAACCAGTTAGTGATCTGCCTACACCTGAATCCCTGAAACATCTGAACTGTTTTGTAAATCATCTTATCCCCAACCTCAGTACCACCGGATCTT CACTTCTCAGTGGGATTTTGTCCTTTGCATGACCCTACTTTCAGCAGGGCTTTGAGGCTGGGAAACTGATCTGCTGGGTGACTTTCATTCCAGTTGCTGG GACGGAAGGCTGAATGTAGGGTCATTTTGTATGGGATATGCAGAGCTCTGGGTTTTTTTGTTTTTTGTTTTTTGAGACGGAGTCTCGCTCTGTCGCCAGG CTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAACCTCCGCCTCCCGGTTCAAGCCATTCTTCTGCCTCAGCCTCAGCGAGTAGCTGAGACTACCGGCG CACGCCACCACGCCCAGCTAATTGTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCTGCC CGCCTCGGCCTCCCAAAGTGCCGAGATTACAGGTGTGAGCCACCGCGCTCGGCCAGAGCTCTGGGTTTTAATCCTACTTTAGCTGTAGAACCTTGGGCAA ATAACTTCATCTTTTTGGGTCCTAATTTTCCTCCTGTCTAACTGGAGGGACTGTGATCCTTCCACCTTGGATGGAAGAGGCTTACCTGACAGCCAGCCTG CCTGCTGGGAGCCAGGAGAGTCAGCTCATTAAATCTTGAAGAACCGCTGTATGCCCTTTTTCCTTCTAAGTCATGTCTGCTGCCTGTGAGCCTGGGAAGG AGTGCTTTCAAAACCTGTATTTTTGCCCTCTTTAGTAAATTTAGAACTGTAGAGGCTAATAAACTGCGATGAGACATTTAA

refseq_BNIPL.F1 (forward primer)
refseq_BNIPL.R1 (reverse primer)
Single exon skipping

Frame 0

MRKRLSAPELRLSLTKGPGNDGASPTQSAPSSP DGSSDLEIDELETPSDSEQLDSGHEFEWEDELPR AEGLGTSETAERLGRGCMWDVTGEDGHHWRVFR MGPREQRVDMTVIEPYKKVLSHGGYHGDGLNAV ILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELL VAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLD RRVL*VILVMERCRSMQKELTRG*STRWKWSRK RPGGRARWLTSVIPALWKAEATEKPASPGGCPCY MVCESISGTASALHQFQIHTKNPFSGQPGGAGP THIPGSSPHP*SCQTAGPGSPWLRRDIAQDWIK GLRTS**SAYT*IPETSELFCKSSYPQPQYHRIF TSQWDFVLCMTLLSAGL*GWETDLLGDFHSSCW DGRLNVGSFCMGYAELWVFLFFVF*DGVSLCRQ AGVQWCDLGSLQPPPPGSSHSSASASASS*DYRR TPPRPANCFVFLVETGFHHVGQDGLDLLTS*SA RLGLPKCRDYRCEPPRSARALGFNPTLAVEPWA NNFIFLGPNFPPV*LEGL*SFHLGWKRLT*QPAC LLGARRVSSLNLEEPLYALFPSKSCLLPVSLGR SAFKTCIFALFSKFRTVEANKLR*DI*

Frame 1

CASVFLPQSCG*V*LRGLEMMELHPPSLHLPLL MAVLTWR*TNWRHLQTRSSWTVDMNLNGKMNYP GQRVWAPVRQLKGWAEVVCGM*LEKMDITGGCSE WDHGSSA*T*LSLSPIRKSCLMEVTTVMASMLS SFLLPVIYPEAASPTTPMSWNTCLGIWWELWSC **LKITCLFI*VEAQAGPKFHL*AGYVSVTVPWI GEFYK*SWSWSDVEACKRNLREGRAQDGNGAEK DQVVGRGGSRL*SQHFGRPRLRKNLRALVVVHA TWYVKAFLALLRPFISSKFTRKIRFLDSLGELAQ LISLDQVHIPEAVRQLDRDLHGSGGT*HRTG*K ALEPVSDLPTPESLKHLNCFVNHLIPNLSTTGS SLLSGILSFA*PYFQQGFEAGKLICWVTFIPVAG TEG*M*GHFVWDMQSSGFFCFLFFETESRSVAR LECSGAISAHCNLRLPVQAILLPQPQRVAETTG ARHHAQLIVLYF**RRGFTMLARMVSIS*PRDLP ASASQSAEITGVSHRARPELWVLILL*L*NLGQ ITSSFWVLIFLLSNWRDCDPSTLDGRGLPDSQP ACWEPGESAH*ILKNRCMPFFLLSHVCCL*AWEG VLSKPVFLPSLVNLEL*RLINCDETF

Frame 2

AQASFCPRVAAESD*GAWK*WSFTHPVCTFLS* WQF*PGDRRIGDTFRLGAAGQWT*I*MGR*TTP GRGSGHQ*DS*KAGPRLYVGCDWRRWTSLEGVP NGTTGAARRHDCH*AL*ESPVSWRLPR*WPQCCH PFCFLLSTQKQHPQLHLCHGTLV*VYGGNSGAA SS*KLPACSFEWRHKQGPSSTSKLDTSVLPYPG SASFISNLGHGAM*KHAKGTYARVEHKMEMEQKK TRWSGAVAHVCNPSTLEGRGYGKTCEPWWLSML HGM*KHFWHCFGPSSVPNSHEKSVFWTAWGSWP NSYPWIKSTSLKLSDSWTGISMAQEGHSTGLDKR P*NQLVICLHLNP*NI*TVL*IILSPTSVPPDL HFSVGFCPLHDPTFSRALRLGN*SAG*LSFQLL GRKAECRVILYGICRALGFFVFCFLRRSLALSPG WSAVVRSRLTATSASRFKPFFCLSLSE*LRLPA HATTPS*LFCIFSRDGVSPCWPGWSRSLDLVIC PPRPPKVPRLQV*ATALGQSSGF*SYFSCRTLGK *LHLFGS*FSSCLTGGTVILPPWMEEAYLTASL PAGSQESQLIKS*RTAVCPFSF*VMSAACEPGK ECFQNLYFCPL**I*NCRG**TAMRHL