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Sequences

Sequence NM_004305

CGCGCCCCTCCCTCCTCGCGGACCTGGCGGTGCCGGCGCCCGGAGTGGCCCTTTAAAAGGCAGCTTATTGTCCGGAGGGGGCGGGCGGGGGGCGCCGACC
GCGGCCTGAGGCCCGGCCCCTCCCCTCTCCCTCCCTCTGTCCCCGCGTCGCTCGCTGGCTAGCTCGCTGGCTCGCTCGCCCGTCCGGCGCACGCTCCGCC
TCCGTCAGTTGGCTCCGCTGTCGGGTGCGCGGCGTGGAGCGGCAGCCGGTCTGGACGCGCGGCCGGGGCTGGGGGCTGGGAGCGCGGCGCGCAAGATCTC
CCCGCGCGAGAGCGGCCCCTGCCACCGGGCGAGGCCTGCGCCGCGATGGCAGAGATGGGCAGTAAAGGGGTGACGGCGGGAAAGATCGCCAGCAACGTGC
AGAAGAAGCTCACCCGCGCGCAGGAGAAGGTTCTCCAGAAGCTGGGGAAGGCAGATGAGACCAAGGATGAGCAGTTTGAGCAGTGCGTCCAGAATTTCAA
CAAGCAGCTGACGGAGGGCACCCGGCTGCAGAAGGATCTCCGGACCTACCTGGCCTCCGTCAAAGCCATGCACGAGGCTTCCAAGAAGCTGAATGAGTGT
CTGCAGGAGGTGTATGAGCCCGATTGGCCCGGCAGGGATGAGGCAAACAAGATCGCAGAGAACAACGACCTGCTGTGGATGGATTACCACCAGAAGCTGG
TGGACCAGGCGCTGCTGACCATGGACACGTACCTGGGCCAGTTCCCCGACATCAAGTCACGCATTGCCAAGCGGGGGCGCAAGCTGGTGGACTACGACAG
TGCCCGGCACCACTACGAGTCCCTTCAAACTGCCAAAAAGAAGGATGAAGCCAAAATTGCCAAGGCCGAGGAGGAGCTCATCAAAGCCCAGAAGGTGTTT
GAGGAGATGAATGTGGATCTGCAGGAGGAGCTGCCGTCCCTGTGGAACAGCCGCGTAGGTTTCTACGTCAACACGTTCCAGAGCATCGCGGGCCTGGAGG
AAAACTTCCACAAGGAGATGAGCAAGCTCAACCAGAACCTCAATGATGTGCTGGTCGGCCTGGAGAAGCAACACGGGAGCAACACCTTCACGGTCAAGGC
CCAGCCCAGAAAGAAAAGTAAACTGTTTTCGCGGCTGCGCAGAAAGAAGAACAGTGACAACGCGCCTGCAAAAGGGAACAAGAGCCCTTCGCCTCCAGAT
GGCTCCCCTGCCGCCACCCCCGAGATCAGAGTCAACCACGAGCCAGAGCCGGCCGGCGGGGCCACGCCCGGGGCCACCCTCCCCAAGTCCCCATCTCAGC
CAGCAGAGGCCTCGGAGGTGGCGGGTGGGACCCAACCTGCGGCTGGAGCCCAGGAGCCAGGGGAGACGGCGGCAAGTGAAGCAGCCTCCAGCTCTCTTCC
TGCTGTCGTGGTGGAGACCTTCCCAGCAACTGTGAATGGCACCGTGGAGGGCGGCAGTGGGGCCGGGCGCTTGGACCTGCCCCCAGGTTTCATGTTCAAG
GTACAGGCCCAGCACGACTACACGGCCACTGACACAGACGAGCTGCAGCTCAAGGCTGGTGATGTGGTGCTGGTGATCCCCTTCCAGAACCCTGAAGAGC
AGGATGAAGGCTGGCTCATGGGCGTGAAGGAGAGCGACTGGAACCAGCACAAGGAGCTGGAGAAGTGCCGTGGCGTCTTCCCCGAGAACTTCACTGAGAG
GGTCCCATGACGGCGGGGCCCAGGCAGCCTCCGGGCGTGTGAAGAACACCTCCTCCCGAAAAATGTGTGGTTCTTTTTTTTGTTTTGTTTTCGTTTTTCA
TCTTTTGAAGAGCAAAGGGAAATCAAGAGGAGACCCCCAGGCAGAGGGGCGTTCTCCCAAAGATTAGGTCGTTTTCCAAAGAGCCGCGTCCCGGCAAGTC
CGGCGGAATTCACCAGTGTTCCTGAAGCTGCTGTGTCCTCTAGTTGAGTTTCTGGCGCCCCTGCCTGTGCCCGCATGTGTGCCTGGCCGCAGGGCGGGGC
TGGGGGCTGCCGAGCCACCATGCTTGCCTGAAGCTTCGGCCGCGCCACCCGGGCAAGGGTCCTCTTTTCCTGGCAGCTGCTGTGGGTGGGGCCCAGACAC
CAGCCTAGCCTGGCTCTGCCCCGCAGACGGTCTGTGTGCTGTTTGAAAATAAATCTTAGTGTTCAAAACAAAATGAAACAAAAAAAAAATGATAAAAACT
CTCAG
  • refseq_BIN1.F3 (forward primer)
  • refseq_BIN1.R3 (reverse primer)
  • Single exon skipping

Frame 0

RAPPSSRTWRCRRPEWPFKRQLIVRRGRAGGAD
RGLRPGPSPLPPSVPASLAG*LAGSLARPAHAPP
PSVGSAVGCAAWSGSRSGRAAGAGGWERGAQDL
PARERPLPPGEACAAMAEMGSKGVTAGKIASNV
QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFN
KQLTEGTRLQKDLRTYLASVKAMHEASKKLNEC
LQEVYEPDWPGRDEANKIAENNDLLWMDYHQKL
VDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDS
ARHHYESLQTAKKKDEAKIAKAEEELIKAQKVF
EEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLE
ENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKA
QPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPD
GSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ
PAEASEVAGGTQPAAGAQEPGETAASEAASSSLP
AVVVETFPATVNGTVEGGSGAGRLDLPPGFMFK
VQAQHDYTATDTDELQLKAGDVVLVIPFQNPEE
QDEGWLMGVKESDWNQHKELEKCRGVFPENFTER
VP*RRGPGSLRACEEHLLPKNVWFFFLFCFRFS
SFEEQREIKRRPPGRGAFSQRLGRFPKSRVPAS
PAEFTSVPEAAVSSS*VSGAPACARMCAWPQGGA
GGCRATMLA*SFGRATRARVLFSWQLLWVGPRH
QPSLALPRRRSVCCLKINLSVQNKMKQKKNDKN
SQ

Frame 1

APLPPRGPGGAGARSGPLKGSLLSGGGGRGAPT
AA*GPAPPLSLPLSPRRSLASSLARSPVRRTLR
LRQLAPLSGARRGAAAGLDARPGLGAGSAARKIS
PRESGPCHRARPAPRWQRWAVKG*RRERSPATC
RRSSPARRRRFSRSWGRQMRPRMSSLSSASRIS
TSS*RRAPGCRRISGPTWPPSKPCTRLPRS*MSV
CRRCMSPIGPAGMRQTRSQRTTTCCGWITTRSW
WTRRC*PWTRTWASSPTSSHALPSGGASWWTTT
VPGTTTSPFKLPKRRMKPKLPRPRRSSSKPRRCL
RR*MWICRRSCRPCGTAA*VSTSTRSRASRAWR
KTSTRR*ASSTRTSMMCWSAWRSNTGATPSRSR
PSPERKVNCFRGCAERRTVTTRLQKGTRALRLQM
APLPPPPRSESTTSQSRPAGPRPGPPSPSPHLS
QQRPRRWRVGPNLRLEPRSQGRRRQVKQPPALF
LLSWWRPSQQL*MAPWRAAVGPGAWTCPQVSCSR
YRPSTTTRPLTQTSCSSRLVMWCW*SPSRTLKS
RMKAGSWA*RRATGTSTRSWRSAVASSPRTSLR
GSHDGGAQAASGRVKNTSSRKMCGSFFCFVFVFH
LLKSKGKSRGDPQAEGRSPKD*VVFQRAASRQV
RRNSPVFLKLLCPLVEFLAPLPVPACVPGRRAG
LGAAEPPCLPEASAAPPGQGSSFPGSCCGWGPDT
SLAWLCPADGLCAV*K*ILVFKTK*NKKKMIKT
L

Frame 2

RPSLLADLAVPAPGVAL*KAAYCPEGAGGGRRP
RPEARPLPSPSLCPRVARWLARWLARPSGARSA
SVSWLRCRVRGVERQPVWTRGRGWGLGARRARS
PRARAAPATGRGLRRDGRDGQ*RGDGGKDRQQRA
EEAHPRAGEGSPEAGEGR*DQG*AV*AVRPEFQ
QAADGGHPAAEGSPDLPGLRQSHARGFQEAE*V
SAGGV*ARLARQG*GKQDRREQRPAVDGLPPEAG
GPGAADHGHVPGPVPRHQVTHCQAGAQAGGLRQ
CPAPLRVPSNCQKEG*SQNCQGRGGAHQSPEGV
*GDECGSAGGAAVPVEQPRRFLRQHVPEHRGPGG
KLPQGDEQAQPEPQ*CAGRPGEATREQHLHGQG
PAQKEK*TVFAAAQKEEQ*QRACKREQEPFASR
WLPCRHPRDQSQPRARAGRRGHARGHPPQVPISA
SRGLGGGGWDPTCGWSPGARGDGGK*SSLQLSS
CCRGGDLPSNCEWHRGGRQWGRALGPAPRFHVQ
GTGPARLHGH*HRRAAAQGW*CGAGDPLPEP*RA
G*RLAHGREGERLEPAQGAGEVPWRLPRELH*E
GPMTAGPRQPPGV*RTPPPEKCVVLFFVLFSFF
IF*RAKGNQEETPRQRGVLPKIRSFSKEPRPGKS
GGIHQCS*SCCVL*LSFWRPCLCPHVCLAAGRG
WGLPSHHACLKLRPRHPGKGPLFLAAAVGGAQT
PA*PGSAPQTVCVLFENKS*CSKQNETKKK**KL
S

Sequence NM_139346

CGCGCCCCTCCCTCCTCGCGGACCTGGCGGTGCCGGCGCCCGGAGTGGCCCTTTAAAAGGCAGCTTATTGTCCGGAGGGGGCGGGCGGGGGGCGCCGACC
GCGGCCTGAGGCCCGGCCCCTCCCCTCTCCCTCCCTCTGTCCCCGCGTCGCTCGCTGGCTAGCTCGCTGGCTCGCTCGCCCGTCCGGCGCACGCTCCGCC
TCCGTCAGTTGGCTCCGCTGTCGGGTGCGCGGCGTGGAGCGGCAGCCGGTCTGGACGCGCGGCCGGGGCTGGGGGCTGGGAGCGCGGCGCGCAAGATCTC
CCCGCGCGAGAGCGGCCCCTGCCACCGGGCGAGGCCTGCGCCGCGATGGCAGAGATGGGCAGTAAAGGGGTGACGGCGGGAAAGATCGCCAGCAACGTGC
AGAAGAAGCTCACCCGCGCGCAGGAGAAGGTTCTCCAGAAGCTGGGGAAGGCAGATGAGACCAAGGATGAGCAGTTTGAGCAGTGCGTCCAGAATTTCAA
CAAGCAGCTGACGGAGGGCACCCGGCTGCAGAAGGATCTCCGGACCTACCTGGCCTCCGTCAAAGCCATGCACGAGGCTTCCAAGAAGCTGAATGAGTGT
CTGCAGGAGGTGTATGAGCCCGATTGGCCCGGCAGGGATGAGGCAAACAAGATCGCAGAGAACAACGACCTGCTGTGGATGGATTACCACCAGAAGCTGG
TGGACCAGGCGCTGCTGACCATGGACACGTACCTGGGCCAGTTCCCCGACATCAAGTCACGCATTGCCAAGCGGGGGCGCAAGCTGGTGGACTACGACAG
TGCCCGGCACCACTACGAGTCCCTTCAAACTGCCAAAAAGAAGGATGAAGCCAAAATTGCCAAGGCCGAGGAGGAGCTCATCAAAGCCCAGAAGGTGTTT
GAGGAGATGAATGTGGATCTGCAGGAGGAGCTGCCGTCCCTGTGGAACAGCCGCGTAGGTTTCTACGTCAACACGTTCCAGAGCATCGCGGGCCTGGAGG
AAAACTTCCACAAGGAGATGAGCAAGCTCAACCAGAACCTCAATGATGTGCTGGTCGGCCTGGAGAAGCAACACGGGAGCAACACCTTCACGGTCAAGGC
CCAGCCCAGAAAGAAAAGTAAACTGTTTTCGCGGCTGCGCAGAAAGAAGAACAGTGACAACGCGCCTGCAAAAGGGAACAAGAGCCCTTCGCCTCCAGAT
GGCTCCCCTGCCGCCACCCCCGAGATCAGAGTCAACCACGAGCCAGAGCCGGCCGGCGGGGCCACGCCCGGGGCCACCCTCCCCAAGTCCCCATCTCAGC
TCCGGAAAGGCCCACCAGTCCCTCCGCCTCCCAAACACACCCCGTCCAAGGAAGTCAAGCAGGAGCAGATCCTCAGCCTGTTTGAGGACACGTTTGTCCC
TGAGATCAGCGTGACCACCCCCTCCCAGCCAGCAGAGGCCTCGGAGGTGGCGGGTGGGACCCAACCTGCGGCTGGAGCCCAGGAGCCAGGGGAGACGGCG
GCAAGTGAAGCAGCCTCCAGCTCTCTTCCTGCTGTCGTGGTGGAGACCTTCCCAGCAACTGTGAATGGCACCGTGGAGGGCGGCAGTGGGGCCGGGCGCT
TGGACCTGCCCCCAGGTTTCATGTTCAAGGTACAGGCCCAGCACGACTACACGGCCACTGACACAGACGAGCTGCAGCTCAAGGCTGGTGATGTGGTGCT
GGTGATCCCCTTCCAGAACCCTGAAGAGCAGGATGAAGGCTGGCTCATGGGCGTGAAGGAGAGCGACTGGAACCAGCACAAGGAGCTGGAGAAGTGCCGT
GGCGTCTTCCCCGAGAACTTCACTGAGAGGGTCCCATGACGGCGGGGCCCAGGCAGCCTCCGGGCGTGTGAAGAACACCTCCTCCCGAAAAATGTGTGGT
TCTTTTTTTTGTTTTGTTTTCGTTTTTCATCTTTTGAAGAGCAAAGGGAAATCAAGAGGAGACCCCCAGGCAGAGGGGCGTTCTCCCAAAGATTAGGTCG
TTTTCCAAAGAGCCGCGTCCCGGCAAGTCCGGCGGAATTCACCAGTGTTCCTGAAGCTGCTGTGTCCTCTAGTTGAGTTTCTGGCGCCCCTGCCTGTGCC
CGCATGTGTGCCTGGCCGCAGGGCGGGGCTGGGGGCTGCCGAGCCACCATGCTTGCCTGAAGCTTCGGCCGCGCCACCCGGGCAAGGGTCCTCTTTTCCT
GGCAGCTGCTGTGGGTGGGGCCCAGACACCAGCCTAGCCTGGCTCTGCCCCGCAGACGGTCTGTGTGCTGTTTGAAAATAAATCTTAGTGTTCAAAACAA
AATGAAACAAAAAAAAAATGATAAAAACTCTCAG
  • refseq_BIN1.F3 (forward primer)
  • refseq_BIN1.R3 (reverse primer)
  • Single exon skipping

Frame 0

RAPPSSRTWRCRRPEWPFKRQLIVRRGRAGGAD
RGLRPGPSPLPPSVPASLAG*LAGSLARPAHAPP
PSVGSAVGCAAWSGSRSGRAAGAGGWERGAQDL
PARERPLPPGEACAAMAEMGSKGVTAGKIASNV
QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFN
KQLTEGTRLQKDLRTYLASVKAMHEASKKLNEC
LQEVYEPDWPGRDEANKIAENNDLLWMDYHQKL
VDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDS
ARHHYESLQTAKKKDEAKIAKAEEELIKAQKVF
EEMNVDLQEELPSLWNSRVGFYVNTFQSIAGLE
ENFHKEMSKLNQNLNDVLVGLEKQHGSNTFTVKA
QPRKKSKLFSRLRRKKNSDNAPAKGNKSPSPPD
GSPAATPEIRVNHEPEPAGGATPGATLPKSPSQ
LRKGPPVPPPPKHTPSKEVKQEQILSLFEDTFVP
EISVTTPSQPAEASEVAGGTQPAAGAQEPGETA
ASEAASSSLPAVVVETFPATVNGTVEGGSGAGR
LDLPPGFMFKVQAQHDYTATDTDELQLKAGDVVL
VIPFQNPEEQDEGWLMGVKESDWNQHKELEKCR
GVFPENFTERVP*RRGPGSLRACEEHLLPKNVW
FFFLFCFRFSSFEEQREIKRRPPGRGAFSQRLGR
FPKSRVPASPAEFTSVPEAAVSSS*VSGAPACA
RMCAWPQGGAGGCRATMLA*SFGRATRARVLFS
WQLLWVGPRHQPSLALPRRRSVCCLKINLSVQNK
MKQKKNDKNSQ

Frame 1

APLPPRGPGGAGARSGPLKGSLLSGGGGRGAPT
AA*GPAPPLSLPLSPRRSLASSLARSPVRRTLR
LRQLAPLSGARRGAAAGLDARPGLGAGSAARKIS
PRESGPCHRARPAPRWQRWAVKG*RRERSPATC
RRSSPARRRRFSRSWGRQMRPRMSSLSSASRIS
TSS*RRAPGCRRISGPTWPPSKPCTRLPRS*MSV
CRRCMSPIGPAGMRQTRSQRTTTCCGWITTRSW
WTRRC*PWTRTWASSPTSSHALPSGGASWWTTT
VPGTTTSPFKLPKRRMKPKLPRPRRSSSKPRRCL
RR*MWICRRSCRPCGTAA*VSTSTRSRASRAWR
KTSTRR*ASSTRTSMMCWSAWRSNTGATPSRSR
PSPERKVNCFRGCAERRTVTTRLQKGTRALRLQM
APLPPPPRSESTTSQSRPAGPRPGPPSPSPHLS
SGKAHQSLRLPNTPRPRKSSRSRSSACLRTRLS
LRSA*PPPPSQQRPRRWRVGPNLRLEPRSQGRRR
QVKQPPALFLLSWWRPSQQL*MAPWRAAVGPGA
WTCPQVSCSRYRPSTTTRPLTQTSCSSRLVMWC
W*SPSRTLKSRMKAGSWA*RRATGTSTRSWRSAV
ASSPRTSLRGSHDGGAQAASGRVKNTSSRKMCG
SFFCFVFVFHLLKSKGKSRGDPQAEGRSPKD*V
VFQRAASRQVRRNSPVFLKLLCPLVEFLAPLPVP
ACVPGRRAGLGAAEPPCLPEASAAPPGQGSSFP
GSCCGWGPDTSLAWLCPADGLCAV*K*ILVFKT
K*NKKKMIKTL

Frame 2

RPSLLADLAVPAPGVAL*KAAYCPEGAGGGRRP
RPEARPLPSPSLCPRVARWLARWLARPSGARSA
SVSWLRCRVRGVERQPVWTRGRGWGLGARRARS
PRARAAPATGRGLRRDGRDGQ*RGDGGKDRQQRA
EEAHPRAGEGSPEAGEGR*DQG*AV*AVRPEFQ
QAADGGHPAAEGSPDLPGLRQSHARGFQEAE*V
SAGGV*ARLARQG*GKQDRREQRPAVDGLPPEAG
GPGAADHGHVPGPVPRHQVTHCQAGAQAGGLRQ
CPAPLRVPSNCQKEG*SQNCQGRGGAHQSPEGV
*GDECGSAGGAAVPVEQPRRFLRQHVPEHRGPGG
KLPQGDEQAQPEPQ*CAGRPGEATREQHLHGQG
PAQKEK*TVFAAAQKEEQ*QRACKREQEPFASR
WLPCRHPRDQSQPRARAGRRGHARGHPPQVPISA
PERPTSPSASQTHPVQGSQAGADPQPV*GHVCP
*DQRDHPLPASRGLGGGGWDPTCGWSPGARGDG
GK*SSLQLSSCCRGGDLPSNCEWHRGGRQWGRAL
GPAPRFHVQGTGPARLHGH*HRRAAAQGW*CGA
GDPLPEP*RAG*RLAHGREGERLEPAQGAGEVP
WRLPRELH*EGPMTAGPRQPPGV*RTPPPEKCVV
LFFVLFSFFIF*RAKGNQEETPRQRGVLPKIRS
FSKEPRPGKSGGIHQCS*SCCVL*LSFWRPCLC
PHVCLAAGRGWGLPSHHACLKLRPRHPGKGPLFL
AAAVGGAQTPA*PGSAPQTVCVLFENKS*CSKQ
NETKKK**KLS

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