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Sequences

Sequence NM_139344

CGCGCCCCTCCCTCCTCGCGGACCTGGCGGTGCCGGCGCCCGGAGTGGCCCTTTAAAAGGCAGCTTATTGTCCGGAGGGGGCGGGCGGGGGGCGCCGACC
GCGGCCTGAGGCCCGGCCCCTCCCCTCTCCCTCCCTCTGTCCCCGCGTCGCTCGCTGGCTAGCTCGCTGGCTCGCTCGCCCGTCCGGCGCACGCTCCGCC
TCCGTCAGTTGGCTCCGCTGTCGGGTGCGCGGCGTGGAGCGGCAGCCGGTCTGGACGCGCGGCCGGGGCTGGGGGCTGGGAGCGCGGCGCGCAAGATCTC
CCCGCGCGAGAGCGGCCCCTGCCACCGGGCGAGGCCTGCGCCGCGATGGCAGAGATGGGCAGTAAAGGGGTGACGGCGGGAAAGATCGCCAGCAACGTGC
AGAAGAAGCTCACCCGCGCGCAGGAGAAGGTTCTCCAGAAGCTGGGGAAGGCAGATGAGACCAAGGATGAGCAGTTTGAGCAGTGCGTCCAGAATTTCAA
CAAGCAGCTGACGGAGGGCACCCGGCTGCAGAAGGATCTCCGGACCTACCTGGCCTCCGTCAAAGCCATGCACGAGGCTTCCAAGAAGCTGAATGAGTGT
CTGCAGGAGGTGTATGAGCCCGATTGGCCCGGCAGGGATGAGGCAAACAAGATCGCAGAGAACAACGACCTGCTGTGGATGGATTACCACCAGAAGCTGG
TGGACCAGGCGCTGCTGACCATGGACACGTACCTGGGCCAGTTCCCCGACATCAAGTCACGCATTGCCAAGCGGGGGCGCAAGCTGGTGGACTACGACAG
TGCCCGGCACCACTACGAGTCCCTTCAAACTGCCAAAAAGAAGGATGAAGCCAAAATTGCCAAGCCTGTCTCGCTGCTTGAGAAAGCCGCCCCCCAGTGG
TGCCAAGGCAAACTGCAGGCTCATCTCGTAGCTCAAACTAACCTGCTCCGAAATCAGGCCGAGGAGGAGCTCATCAAAGCCCAGAAGGTGTTTGAGGAGA
TGAATGTGGATCTGCAGGAGGAGCTGCCGTCCCTGTGGAACAGCCGCGTAGGTTTCTACGTCAACACGTTCCAGAGCATCGCGGGCCTGGAGGAAAACTT
CCACAAGGAGATGAGCAAGCTCAACCAGAACCTCAATGATGTGCTGGTCGGCCTGGAGAAGCAACACGGGAGCAACACCTTCACGGTCAAGGCCCAGCCC
AGTGACAACGCGCCTGCAAAAGGGAACAAGAGCCCTTCGCCTCCAGATGGCTCCCCTGCCGCCACCCCCGAGATCAGAGTCAACCACGAGCCAGAGCCGG
CCGGCGGGGCCACGCCCGGGGCCACCCTCCCCAAGTCCCCATCTCAGTTTGAGGCCCCGGGGCCTTTCTCGGAGCAGGCCAGTCTGCTGGACCTGGACTT
TGACCCCCTCCCGCCCGTGACGAGCCCTGTGAAGGCACCCACGCCCTCTGGTCAGTCAATTCCATGGGACCTCTGGGAGCCCACAGAGAGTCCAGCCGGC
AGCCTGCCTTCCGGGGAGCCCAGCGCTGCCGAGGGCACCTTTGCTGTGTCCTGGCCCAGCCAGACGGCCGAGCCGGGGCCTGCCCAACCAGCAGAGGCCT
CGGAGGTGGCGGGTGGGACCCAACCTGCGGCTGGAGCCCAGGAGCCAGGGGAGACGGCGGCAAGTGAAGCAGCCTCCAGCTCTCTTCCTGCTGTCGTGGT
GGAGACCTTCCCAGCAACTGTGAATGGCACCGTGGAGGGCGGCAGTGGGGCCGGGCGCTTGGACCTGCCCCCAGGTTTCATGTTCAAGGTACAGGCCCAG
CACGACTACACGGCCACTGACACAGACGAGCTGCAGCTCAAGGCTGGTGATGTGGTGCTGGTGATCCCCTTCCAGAACCCTGAAGAGCAGGATGAAGGCT
GGCTCATGGGCGTGAAGGAGAGCGACTGGAACCAGCACAAGGAGCTGGAGAAGTGCCGTGGCGTCTTCCCCGAGAACTTCACTGAGAGGGTCCCATGACG
GCGGGGCCCAGGCAGCCTCCGGGCGTGTGAAGAACACCTCCTCCCGAAAAATGTGTGGTTCTTTTTTTTGTTTTGTTTTCGTTTTTCATCTTTTGAAGAG
CAAAGGGAAATCAAGAGGAGACCCCCAGGCAGAGGGGCGTTCTCCCAAAGATTAGGTCGTTTTCCAAAGAGCCGCGTCCCGGCAAGTCCGGCGGAATTCA
CCAGTGTTCCTGAAGCTGCTGTGTCCTCTAGTTGAGTTTCTGGCGCCCCTGCCTGTGCCCGCATGTGTGCCTGGCCGCAGGGCGGGGCTGGGGGCTGCCG
AGCCACCATGCTTGCCTGAAGCTTCGGCCGCGCCACCCGGGCAAGGGTCCTCTTTTCCTGGCAGCTGCTGTGGGTGGGGCCCAGACACCAGCCTAGCCTG
GCTCTGCCCCGCAGACGGTCTGTGTGCTGTTTGAAAATAAATCTTAGTGTTCAAAACAAAATGAAACAAAAAAAAAATGATAAAAACTCTCAG
  • refseq_BIN1.F4 (forward primer)
  • refseq_BIN1.R4 (reverse primer)
  • Single exon skipping

Frame 0

RAPPSSRTWRCRRPEWPFKRQLIVRRGRAGGAD
RGLRPGPSPLPPSVPASLAG*LAGSLARPAHAPP
PSVGSAVGCAAWSGSRSGRAAGAGGWERGAQDL
PARERPLPPGEACAAMAEMGSKGVTAGKIASNV
QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFN
KQLTEGTRLQKDLRTYLASVKAMHEASKKLNEC
LQEVYEPDWPGRDEANKIAENNDLLWMDYHQKL
VDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDS
ARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQW
CQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEE
MNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF
HKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP
SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEP
AGGATPGATLPKSPSQFEAPGPFSEQASLLDLDF
DPLPPVTSPVKAPTPSGQSIPWDLWEPTESPAG
SLPSGEPSAAEGTFAVSWPSQTAEPGPAQPAEA
SEVAGGTQPAAGAQEPGETAASEAASSSLPAVVV
ETFPATVNGTVEGGSGAGRLDLPPGFMFKVQAQ
HDYTATDTDELQLKAGDVVLVIPFQNPEEQDEG
WLMGVKESDWNQHKELEKCRGVFPENFTERVP*R
RGPGSLRACEEHLLPKNVWFFFLFCFRFSSFEE
QREIKRRPPGRGAFSQRLGRFPKSRVPASPAEF
TSVPEAAVSSS*VSGAPACARMCAWPQGGAGGCR
ATMLA*SFGRATRARVLFSWQLLWVGPRHQPSL
ALPRRRSVCCLKINLSVQNKMKQKKNDKNSQ

Frame 1

APLPPRGPGGAGARSGPLKGSLLSGGGGRGAPT
AA*GPAPPLSLPLSPRRSLASSLARSPVRRTLR
LRQLAPLSGARRGAAAGLDARPGLGAGSAARKIS
PRESGPCHRARPAPRWQRWAVKG*RRERSPATC
RRSSPARRRRFSRSWGRQMRPRMSSLSSASRIS
TSS*RRAPGCRRISGPTWPPSKPCTRLPRS*MSV
CRRCMSPIGPAGMRQTRSQRTTTCCGWITTRSW
WTRRC*PWTRTWASSPTSSHALPSGGASWWTTT
VPGTTTSPFKLPKRRMKPKLPSLSRCLRKPPPSG
AKANCRLIS*LKLTCSEIRPRRSSSKPRRCLRR
*MWICRRSCRPCGTAA*VSTSTRSRASRAWRKT
STRR*ASSTRTSMMCWSAWRSNTGATPSRSRPSP
VTTRLQKGTRALRLQMAPLPPPPRSESTTSQSR
PAGPRPGPPSPSPHLSLRPRGLSRSRPVCWTWT
LTPSRP*RAL*RHPRPLVSQFHGTSGSPQRVQPA
ACLPGSPALPRAPLLCPGPARRPSRGLPNQQRP
RRWRVGPNLRLEPRSQGRRRQVKQPPALFLLSW
WRPSQQL*MAPWRAAVGPGAWTCPQVSCSRYRPS
TTTRPLTQTSCSSRLVMWCW*SPSRTLKSRMKA
GSWA*RRATGTSTRSWRSAVASSPRTSLRGSHD
GGAQAASGRVKNTSSRKMCGSFFCFVFVFHLLKS
KGKSRGDPQAEGRSPKD*VVFQRAASRQVRRNS
PVFLKLLCPLVEFLAPLPVPACVPGRRAGLGAA
EPPCLPEASAAPPGQGSSFPGSCCGWGPDTSLAW
LCPADGLCAV*K*ILVFKTK*NKKKMIKTL

Frame 2

RPSLLADLAVPAPGVAL*KAAYCPEGAGGGRRP
RPEARPLPSPSLCPRVARWLARWLARPSGARSA
SVSWLRCRVRGVERQPVWTRGRGWGLGARRARS
PRARAAPATGRGLRRDGRDGQ*RGDGGKDRQQRA
EEAHPRAGEGSPEAGEGR*DQG*AV*AVRPEFQ
QAADGGHPAAEGSPDLPGLRQSHARGFQEAE*V
SAGGV*ARLARQG*GKQDRREQRPAVDGLPPEAG
GPGAADHGHVPGPVPRHQVTHCQAGAQAGGLRQ
CPAPLRVPSNCQKEG*SQNCQACLAA*ESRPPV
VPRQTAGSSRSSN*PAPKSGRGGAHQSPEGV*GD
ECGSAGGAAVPVEQPRRFLRQHVPEHRGPGGKL
PQGDEQAQPEPQ*CAGRPGEATREQHLHGQGPA
Q*QRACKREQEPFASRWLPCRHPRDQSQPRARAG
RRGHARGHPPQVPISV*GPGAFLGAGQSAGPGL
*PPPARDEPCEGTHALWSVNSMGPLGAHRESSR
QPAFRGAQRCRGHLCCVLAQPDGRAGACPTSRGL
GGGGWDPTCGWSPGARGDGGK*SSLQLSSCCRG
GDLPSNCEWHRGGRQWGRALGPAPRFHVQGTGP
ARLHGH*HRRAAAQGW*CGAGDPLPEP*RAG*RL
AHGREGERLEPAQGAGEVPWRLPRELH*EGPMT
AGPRQPPGV*RTPPPEKCVVLFFVLFSFFIF*R
AKGNQEETPRQRGVLPKIRSFSKEPRPGKSGGIH
QCS*SCCVL*LSFWRPCLCPHVCLAAGRGWGLP
SHHACLKLRPRHPGKGPLFLAAAVGGAQTPA*P
GSAPQTVCVLFENKS*CSKQNETKKK**KLS

Sequence NM_139343

CGCGCCCCTCCCTCCTCGCGGACCTGGCGGTGCCGGCGCCCGGAGTGGCCCTTTAAAAGGCAGCTTATTGTCCGGAGGGGGCGGGCGGGGGGCGCCGACC
GCGGCCTGAGGCCCGGCCCCTCCCCTCTCCCTCCCTCTGTCCCCGCGTCGCTCGCTGGCTAGCTCGCTGGCTCGCTCGCCCGTCCGGCGCACGCTCCGCC
TCCGTCAGTTGGCTCCGCTGTCGGGTGCGCGGCGTGGAGCGGCAGCCGGTCTGGACGCGCGGCCGGGGCTGGGGGCTGGGAGCGCGGCGCGCAAGATCTC
CCCGCGCGAGAGCGGCCCCTGCCACCGGGCGAGGCCTGCGCCGCGATGGCAGAGATGGGCAGTAAAGGGGTGACGGCGGGAAAGATCGCCAGCAACGTGC
AGAAGAAGCTCACCCGCGCGCAGGAGAAGGTTCTCCAGAAGCTGGGGAAGGCAGATGAGACCAAGGATGAGCAGTTTGAGCAGTGCGTCCAGAATTTCAA
CAAGCAGCTGACGGAGGGCACCCGGCTGCAGAAGGATCTCCGGACCTACCTGGCCTCCGTCAAAGCCATGCACGAGGCTTCCAAGAAGCTGAATGAGTGT
CTGCAGGAGGTGTATGAGCCCGATTGGCCCGGCAGGGATGAGGCAAACAAGATCGCAGAGAACAACGACCTGCTGTGGATGGATTACCACCAGAAGCTGG
TGGACCAGGCGCTGCTGACCATGGACACGTACCTGGGCCAGTTCCCCGACATCAAGTCACGCATTGCCAAGCGGGGGCGCAAGCTGGTGGACTACGACAG
TGCCCGGCACCACTACGAGTCCCTTCAAACTGCCAAAAAGAAGGATGAAGCCAAAATTGCCAAGCCTGTCTCGCTGCTTGAGAAAGCCGCCCCCCAGTGG
TGCCAAGGCAAACTGCAGGCTCATCTCGTAGCTCAAACTAACCTGCTCCGAAATCAGGCCGAGGAGGAGCTCATCAAAGCCCAGAAGGTGTTTGAGGAGA
TGAATGTGGATCTGCAGGAGGAGCTGCCGTCCCTGTGGAACAGCCGCGTAGGTTTCTACGTCAACACGTTCCAGAGCATCGCGGGCCTGGAGGAAAACTT
CCACAAGGAGATGAGCAAGCTCAACCAGAACCTCAATGATGTGCTGGTCGGCCTGGAGAAGCAACACGGGAGCAACACCTTCACGGTCAAGGCCCAGCCC
AGTGACAACGCGCCTGCAAAAGGGAACAAGAGCCCTTCGCCTCCAGATGGCTCCCCTGCCGCCACCCCCGAGATCAGAGTCAACCACGAGCCAGAGCCGG
CCGGCGGGGCCACGCCCGGGGCCACCCTCCCCAAGTCCCCATCTCAGCTCCGGAAAGGCCCACCAGTCCCTCCGCCTCCCAAACACACCCCGTCCAAGGA
AGTCAAGCAGGAGCAGATCCTCAGCCTGTTTGAGGACACGTTTGTCCCTGAGATCAGCGTGACCACCCCCTCCCAG
TTTGAGGCCCCGGGGCCTTTCTCG
GAGCAGGCCAGTCTGCTGGACCTGGACTTTGACCCCCTCCCGCCCGTGACGAGCCCTGTGAAGGCACCCACGCCCTCTGGTCAGTCAATTCCATGGGACC
TCTGGGAGCCCACAGAGAGTCCAGCCGGCAGCCTGCCTTCCGGGGAGCCCAGCGCTGCCGAGGGCACCTTTGCTGTGTCCTGGCCCAGCCAGACGGCCGA
GCCGGGGCCTGCCCAACCAGCAGAGGCCTCGGAGGTGGCGGGTGGGACCCAACCTGCGGCTGGAGCCCAGGAGCCAGGGGAGACGGCGGCAAGTGAAGCA
GCCTCCAGCTCTCTTCCTGCTGTCGTGGTGGAGACCTTCCCAGCAACTGTGAATGGCACCGTGGAGGGCGGCAGTGGGGCCGGGCGCTTGGACCTGCCCC
CAGGTTTCATGTTCAAGGTACAGGCCCAGCACGACTACACGGCCACTGACACAGACGAGCTGCAGCTCAAGGCTGGTGATGTGGTGCTGGTGATCCCCTT
CCAGAACCCTGAAGAGCAGGATGAAGGCTGGCTCATGGGCGTGAAGGAGAGCGACTGGAACCAGCACAAGGAGCTGGAGAAGTGCCGTGGCGTCTTCCCC
GAGAACTTCACTGAGAGGGTCCCATGACGGCGGGGCCCAGGCAGCCTCCGGGCGTGTGAAGAACACCTCCTCCCGAAAAATGTGTGGTTCTTTTTTTTGT
TTTGTTTTCGTTTTTCATCTTTTGAAGAGCAAAGGGAAATCAAGAGGAGACCCCCAGGCAGAGGGGCGTTCTCCCAAAGATTAGGTCGTTTTCCAAAGAG
CCGCGTCCCGGCAAGTCCGGCGGAATTCACCAGTGTTCCTGAAGCTGCTGTGTCCTCTAGTTGAGTTTCTGGCGCCCCTGCCTGTGCCCGCATGTGTGCC
TGGCCGCAGGGCGGGGCTGGGGGCTGCCGAGCCACCATGCTTGCCTGAAGCTTCGGCCGCGCCACCCGGGCAAGGGTCCTCTTTTCCTGGCAGCTGCTGT
GGGTGGGGCCCAGACACCAGCCTAGCCTGGCTCTGCCCCGCAGACGGTCTGTGTGCTGTTTGAAAATAAATCTTAGTGTTCAAAACAAAATGAAACAAAA
AAAAAATGATAAAAACTCTCAG
  • refseq_BIN1.F4 (forward primer)
  • refseq_BIN1.R4 (reverse primer)
  • Single exon skipping

Frame 0

RAPPSSRTWRCRRPEWPFKRQLIVRRGRAGGAD
RGLRPGPSPLPPSVPASLAG*LAGSLARPAHAPP
PSVGSAVGCAAWSGSRSGRAAGAGGWERGAQDL
PARERPLPPGEACAAMAEMGSKGVTAGKIASNV
QKKLTRAQEKVLQKLGKADETKDEQFEQCVQNFN
KQLTEGTRLQKDLRTYLASVKAMHEASKKLNEC
LQEVYEPDWPGRDEANKIAENNDLLWMDYHQKL
VDQALLTMDTYLGQFPDIKSRIAKRGRKLVDYDS
ARHHYESLQTAKKKDEAKIAKPVSLLEKAAPQW
CQGKLQAHLVAQTNLLRNQAEEELIKAQKVFEE
MNVDLQEELPSLWNSRVGFYVNTFQSIAGLEENF
HKEMSKLNQNLNDVLVGLEKQHGSNTFTVKAQP
SDNAPAKGNKSPSPPDGSPAATPEIRVNHEPEP
AGGATPGATLPKSPSQLRKGPPVPPPPKHTPSKE
VKQEQILSLFEDTFVPEISVTTPSQ
FEAPGPFS
EQASLLDLDFDPLPPVTSPVKAPTPSGQSIPWD
LWEPTESPAGSLPSGEPSAAEGTFAVSWPSQTAE
PGPAQPAEASEVAGGTQPAAGAQEPGETAASEA
ASSSLPAVVVETFPATVNGTVEGGSGAGRLDLP
PGFMFKVQAQHDYTATDTDELQLKAGDVVLVIPF
QNPEEQDEGWLMGVKESDWNQHKELEKCRGVFP
ENFTERVP*RRGPGSLRACEEHLLPKNVWFFFL
FCFRFSSFEEQREIKRRPPGRGAFSQRLGRFPKS
RVPASPAEFTSVPEAAVSSS*VSGAPACARMCA
WPQGGAGGCRATMLA*SFGRATRARVLFSWQLL
WVGPRHQPSLALPRRRSVCCLKINLSVQNKMKQK
KNDKNSQ

Frame 1

APLPPRGPGGAGARSGPLKGSLLSGGGGRGAPT
AA*GPAPPLSLPLSPRRSLASSLARSPVRRTLR
LRQLAPLSGARRGAAAGLDARPGLGAGSAARKIS
PRESGPCHRARPAPRWQRWAVKG*RRERSPATC
RRSSPARRRRFSRSWGRQMRPRMSSLSSASRIS
TSS*RRAPGCRRISGPTWPPSKPCTRLPRS*MSV
CRRCMSPIGPAGMRQTRSQRTTTCCGWITTRSW
WTRRC*PWTRTWASSPTSSHALPSGGASWWTTT
VPGTTTSPFKLPKRRMKPKLPSLSRCLRKPPPSG
AKANCRLIS*LKLTCSEIRPRRSSSKPRRCLRR
*MWICRRSCRPCGTAA*VSTSTRSRASRAWRKT
STRR*ASSTRTSMMCWSAWRSNTGATPSRSRPSP
VTTRLQKGTRALRLQMAPLPPPPRSESTTSQSR
PAGPRPGPPSPSPHLSSGKAHQSLRLPNTPRPR
KSSRSRSSACLRTRLSLRSA*PPPPS
LRPRGLSR
SRPVCWTWTLTPSRP*RAL*RHPRPLVSQFHGT
SGSPQRVQPAACLPGSPALPRAPLLCPGPARRP
SRGLPNQQRPRRWRVGPNLRLEPRSQGRRRQVKQ
PPALFLLSWWRPSQQL*MAPWRAAVGPGAWTCP
QVSCSRYRPSTTTRPLTQTSCSSRLVMWCW*SP
SRTLKSRMKAGSWA*RRATGTSTRSWRSAVASSP
RTSLRGSHDGGAQAASGRVKNTSSRKMCGSFFC
FVFVFHLLKSKGKSRGDPQAEGRSPKD*VVFQR
AASRQVRRNSPVFLKLLCPLVEFLAPLPVPACVP
GRRAGLGAAEPPCLPEASAAPPGQGSSFPGSCC
GWGPDTSLAWLCPADGLCAV*K*ILVFKTK*NK
KKMIKTL

Frame 2

RPSLLADLAVPAPGVAL*KAAYCPEGAGGGRRP
RPEARPLPSPSLCPRVARWLARWLARPSGARSA
SVSWLRCRVRGVERQPVWTRGRGWGLGARRARS
PRARAAPATGRGLRRDGRDGQ*RGDGGKDRQQRA
EEAHPRAGEGSPEAGEGR*DQG*AV*AVRPEFQ
QAADGGHPAAEGSPDLPGLRQSHARGFQEAE*V
SAGGV*ARLARQG*GKQDRREQRPAVDGLPPEAG
GPGAADHGHVPGPVPRHQVTHCQAGAQAGGLRQ
CPAPLRVPSNCQKEG*SQNCQACLAA*ESRPPV
VPRQTAGSSRSSN*PAPKSGRGGAHQSPEGV*GD
ECGSAGGAAVPVEQPRRFLRQHVPEHRGPGGKL
PQGDEQAQPEPQ*CAGRPGEATREQHLHGQGPA
Q*QRACKREQEPFASRWLPCRHPRDQSQPRARAG
RRGHARGHPPQVPISAPERPTSPSASQTHPVQG
SQAGADPQPV*GHVCP*DQRDHPLP
V*GPGAFL
GAGQSAGPGL*PPPARDEPCEGTHALWSVNSMGP
LGAHRESSRQPAFRGAQRCRGHLCCVLAQPDGR
AGACPTSRGLGGGGWDPTCGWSPGARGDGGK*S
SLQLSSCCRGGDLPSNCEWHRGGRQWGRALGPAP
RFHVQGTGPARLHGH*HRRAAAQGW*CGAGDPL
PEP*RAG*RLAHGREGERLEPAQGAGEVPWRLP
RELH*EGPMTAGPRQPPGV*RTPPPEKCVVLFFV
LFSFFIF*RAKGNQEETPRQRGVLPKIRSFSKE
PRPGKSGGIHQCS*SCCVL*LSFWRPCLCPHVC
LAAGRGWGLPSHHACLKLRPRHPGKGPLFLAAAV
GGAQTPA*PGSAPQTVCVLFENKS*CSKQNETK
KK**KLS

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