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Sequences

Sequence NM_001003398

ATTTCCTTCTCCCTTTCCCCGCCAGCTTCGCATCCATCTCCCCCACCCCGTAACCCCCTCCTGCCTCCATCCACCGGGGCTATGGCCGCAGAAGAGGTAT TGCAGACGGTGGACCATTATAAGACTGAGATAGAGAGGCTAACCAAGGAGCTCACGGAGACCACCCACGAGAAGATCCAGGCTGCCGAGTACGGGCTGGT GGTGCTGGAGGAGAAGCTGACCCTCAAACAGCAGTATGATGAACTGGAGGCTGAGTACGACAGCCTCAAACAGGAGCTGGAGCAGCTCAAAGAGGCATTT GGGCAGTCCTTCTCCATCCACCGGAAGGTTGCTGAAGATGGAGAGACTCGGGAGGAAACGCTTCTGCAGGAGTCAGCATCGAAGGAGGCTTACTATCTGG GGAAGATCTTGGAGATGCAGAACGAGCTGAAACAGAGCCGGGCTGTGGTCACTAATGTACAGGCAGAAAACGAGAGGCTCACCGCAGTCGTGCAGGATCT GAAGGAGAACAATGAGATGGTGGAGCTACAGAGAATACGGATGAAGGATGAAATCCGAGAATATAAGTTCCGGGAGGCACGGCTCCTTCAGGACTATACT GAATTGGAAGAAGAAAATATCACATTGCAGAAACTAGTGTCCACGTTGAAGCAGAACCAGGTTGAATACGAAGGCTTAAAGCATGAGATTAAGCGATTTG AGGAGGAGACGGTACTGCTGAACAGCCAGCTGGAAGATGCCATCCGATTGAAAGAGATTGCTGAGCACCAACTGGAAGAAGCCCTCGAGACTTTAAAAAA TGAAAGAGAGCAAAAGAACAACCTGCGGAAGGAGCTCTCCCAGTATATCAGCCTCAATGATAACCATATCAGCATCTCAGTAGATGGACTCAAATTTGCC GAGGATGGGAGTGAACCAAACAATGATGACAAAATGAACGGTCATATCCATGGGCCTCTTGTGAAACTGAATGGAGACTATCGGACTCCCACCTTAAGGA AAGGAGAGTCTCTGAACCCTGTCTCTGACTTATTCAGTGAGCTGAACATTTCAGAAATACAGAAGTTGAAGCAGCAGCTTATGCAGGTAGAGCGGGAAAA GGCCATTCTTTTGGCCAACCTACAGGAGTCACAGACACAGCTGGAACACACCAAGGGGGCACTGACGGAGCAGCATGAGCGGGTGCACCGGCTCACAGAG CACGTCAATGCCATGAGGGGCCTGCAAAGCAGCAAGGAGCTCAAGGCTGAGCTGGACGGGGAGAAGGGCCGGGACTCAGGGGAGGAGGCCCATGACTATG AGGTGGACATCAATGGTTTAGAGATCCTTGAATGCAAATACAGGGTGGCAGTAACTGAGGTGATTGATCTGAAAGCTGAAATTAAGGCCTTAAAGGAGAA ATATAATAAATCTGTAGAAAACTACACTGATGAGAAGGCCAAGTATGAGAGTAAAATCCAGATGTATGATGAGCAGGTGACAAGCCTTGAGAAGACCACC AAGGAGAGTGGTGAGAAGATGGCCCACATGGAGAAGGAGTTGCAAAAGATGACCAGCATAGCCAACGAAAATCACAGTACCCTTAATACGGCCCAGGATG AGTTAGTGACATTCAGTGAGGAGTTAGCTCAGCTTTACCACCATGTGTGTCTATGTAATAATGAAACTCCCAACAGGGTCATGCTGGATTACTATAGGCA GAGCAGAGTCACCCGCAGTGGCAGCCTGAAAGGGCCCGATGATCCCAGAGGACTTTTGTCCCCACGATTAGCCAGGCGGGGTGTGTCATCCCCGGTAGAA ACAAGGACCTCATCTGAACCAGTTGCAAAAGAAAGCACAGAGGCCAGCAAAGAACCAAGTCCAACTAAGACCCCCACAATCTCTCCTGTTATTACTGCCC CACCGTCATCTCCAGTATTGGATACAAGTGACATCCGCAAAGAGCCAATGAATATCTACAACCTTAATGCCATAATCCGGGACCAAATCAAGCATCTGCA GAAAGCTGTGGACCGGTCCTTGCAACTGTCTCGTCAAAGAGCAGCGGCTCGGGAGCTAGCCCCCATGATTGATAAAGACAAGGAAGCCTTAATGGAAGAG ATCCTCAAGCTAAAGTCCCTGCTGAGCACCAAACGGGAGCAGATCGCCACATTGAGGGCGGTGTTGAAAGCCAACAAGCAGACAGCTGAGGTGGCGCTAG CTAATCTCAAGAACAAATATGAAAATGAAAAAGCAATGGTGACTGAAACCATGACGAAGCTTAGAAATGAACTGAAGGCTTTGAAAGAAGATGCTGCAAC CTTCTCATCCCTGAGAGCAATGTTTGCAACAAGATGTGATGAATATGTCACCCAGTTGGATGAGATGCAGAGACAGTTAGCAGCTGCAGAGGATGAGAAG AAGACTCTGAACACTTTGTTACGAATGGCTATCCAGCAAAAACTCGCCCTGACCCAGAGGCTGGAGGACTTAGAGTTTGACCATGAGCAGTCCCGACGCA GCAAAGGCAAACTTGGAAAGAGCAAGATCGGCAGCCCTAAAATTGTCAGCAGCCTGCTGCCTCCGTACCGCCACAGTGCTCACAACTAGCCGGGAGGCAA GACTGCCCAACTGTCAGTCCTGACACAGCTCTCCCTGAGGAGCAGCCACATTCCAGCTCCCAGTGCGCCCCTCTCCACTGTCTCTCCAAGCCTCCTCACC CCTAGTCTTCATCTCCTGTGGACGAACATCTGGGGTGGAAGTTTTGTAGCCACACACAGGATACTGCCCAAGATCCAGCGGGTGTTTTCTTCTCGGTTGT TAGATGTACAATTGGATTAATGTCCATCGTTTTGGAAGACGAGAGAAAGTTGAGAAGAACACGAAGCACAGACCCTGATGTGATAAAACATTTTGTGGTT TCTCTGAGTCACAGATAAACTTCTGCCATCAAATGGCTACAGTTCATTTAAATTTAAAAAAAAGAAAAAAGAAACAGAAAACGTGTCTCAGATGGCTGGC TTTACCTCGATAGCATAAGAGAGACCTAAGACATGTAAAATACGTATATTGCAGTATCATCTTTCCTCACACTCCAAATTCAGCTAGGGAAGTTGATTCC AATATGTTTGTCATTGATATTTATTTTGTACTTTATTTGCTACATGATTTATGTCTATACAAATAATTTCTCTGAGGTGAATTTAATTCATTTATTTTCA AATAAGCATAATTTGCTCAATTAAGTATGAGTTTGAATTTAGTTTGAAATCTGGAATTGGCCAGACTGTGGTCATTTTTCTTGCA

refseq_BICD1.F2 (forward primer)
refseq_BICD1.R2 (reverse primer)
Exon skipping and alternative donor or acceptor

Frame 0

ISFSLSPPASHPSPPPRNPLLPPSTGAMAAEEV LQTVDHYKTEIERLTKELTETTHEKIQAAEYGLV VLEEKLTLKQQYDELEAEYDSLKQELEQLKEAF GQSFSIHRKVAEDGETREETLLQESASKEAYYL GKILEMQNELKQSRAVVTNVQAENERLTAVVQDL KENNEMVELQRIRMKDEIREYKFREARLLQDYT ELEEENITLQKLVSTLKQNQVEYEGLKHEIKRF EEETVLLNSQLEDAIRLKEIAEHQLEEALETLKN EREQKNNLRKELSQYISLNDNHISISVDGLKFA EDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLR KGESLNPVSDLFSELNISEIQKLKQQLMQVEREK AILLANLQESQTQLEHTKGALTEQHERVHRLTE HVNAMRGLQSSKELKAELDGEKGRDSGEEAHDY EVDINGLEILECKYRVAVTEVIDLKAEIKALKEK YNKSVENYTDEKAKYESKIQMYDEQVTSLEKTT KESGEKMAHMEKELQKMTSIANENHSTLNTAQD ELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQ SRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVE TRTSSEPVAKESTEASKEPSPTKTPTISPVITA PPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQ KAVDRSLQLSRQRAAARELAPMIDKDKEALMEE ILKLKSLLSTKREQIATLRAVLKANKQTAEVAL ANLKNKYENEKAMVTETMTKLRNELKALKEDAAT FSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEK KTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRR SKGKLGKSKIGSPKIVSSLLPPYRHSAHN*PGGK TAQLSVLTQLSLRSSHIPAPSAPLSTVSPSLLT PSLHLLWTNIWGGSFVATHRILPKIQRVFSSRL LDVQLD*CPSFWKTRES*EEHEAQTLM**NILWF L*VTDKLLPSNGYSSFKFKKKKKETENVSQMAG FTSIA*ERPKTCKIRILQYHLSSHSKFS*GS*F QYVCH*YLFCTLFAT*FMSIQIISLR*I*FIYFQ ISIICSIKYEFEFSLKSGIGQTVVIFLA

Frame 1

FPSPFPRQLRIHLPHPVTPSCLHPPGLWPQKRY CRRWTIIRLR*RG*PRSSRRPPTRRSRLPSTGW WCWRRS*PSNSSMMNWRLSTTASNRSWSSSKRHL GSPSPSTGRLLKMERLGRKRFCRSQHRRRLTIW GRSWRCRTS*NRAGLWSLMYRQKTRGSPQSCRI *RRTMRWWSYREYG*RMKSENISSGRHGSFRTIL NWKKKISHCRN*CPR*SRTRLNTKA*SMRLSDL RRRRYC*TASWKMPSD*KRLLSTNWKKPSRL*K MKESKRTTCGRSSPSISASMITISASQ*MDSNLP RMGVNQTMMTK*TVISMGLL*N*METIGLPP*G KESL*TLSLTYSVS*TFQKYRS*SSSLCR*SGK RPFFWPTYRSHRHSWNTPRGH*RSSMSGCTGSQS TSMP*GACKAARSSRLSWTGRRAGTQGRRPMTM RWTSMV*RSLNANTGWQ*LR*LI*KLKLRP*RR NIINL*KTTLMRRPSMRVKSRCMMSR*QALRRPP RRVVRRWPTWRRSCKR*PA*PTKITVPLIRPRM S**HSVRS*LSFTTMCVYVIMKLPTGSCWITIG RAESPAVAA*KGPMIPEDFCPHD*PGGVCHPR*K QGPHLNQLQKKAQRPAKNQVQLRPPQSLLLLLP HRHLQYWIQVTSAKSQ*ISTTLMP*SGTKSSIC RKLWTGPCNCLVKEQRLGS*PP*LIKTRKP*WKR SSS*SPC*APNGSRSPH*GRC*KPTSRQLRWR* LISRTNMKMKKQW*LKP*RSLEMN*RL*KKMLQ PSHP*EQCLQQDVMNMSPSWMRCRDS*QLQRMRR RL*TLCYEWLSSKNSP*PRGWRT*SLTMSSPDA AKANLERARSAALKLSAACCLRTATVLTTSREA RLPNCQS*HSSP*GAATFQLPVRPSPLSLQASSP LVFISCGRTSGVEVL*PHTGYCPRSSGCFLLGC *MYNWINVHRFGRREKVEKNTKHRP*CDKTFCG FSESQINFCHQMATVHLNLKKRKKKQKTCLRWLA LPR*HKRDLRHVKYVYCSIIFPHTPNSAREVDS NMFVIDIYFVLYLLHDLCLYK*FL*GEFNSFIF K*A*FAQLSMSLNLV*NLELARLWSFFL

Frame 2

FLLPFPASFASISPTP*PPPASIHRGYGRRRGI ADGGPL*D*DREANQGAHGDHPREDPGCRVRAG GAGGEADPQTAV**TGG*VRQPQTGAGAAQRGI WAVLLHPPEGC*RWRDSGGNASAGVSIEGGLLSG EDLGDAERAETEPGCGH*CTGRKREAHRSRAGS EGEQ*DGGATENTDEG*NPRI*VPGGTAPSGLY *IGRRKYHIAETSVHVEAEPG*IRRLKA*D*AI* GGDGTAEQPAGRCHPIERDC*APTGRSPRDFKK *KRAKEQPAEGALPVYQPQ**PYQHLSRWTQIC RGWE*TKQ**QNERSYPWASCETEWRLSDSHLKE RRVSEPCL*LIQ*AEHFRNTEVEAAAYAGRAGK GHSFGQPTGVTDTAGTHQGGTDGAA*AGAPAHR ARQCHEGPAKQQGAQG*AGRGEGPGLRGGGP*L* GGHQWFRDP*MQIQGGSN*GD*SES*N*GLKGE I**ICRKLH**EGQV*E*NPDV**AGDKP*EDH QGEW*EDGPHGEGVAKDDQHSQRKSQYP*YGPG* VSDIQ*GVSSALPPCVSM***NSQQGHAGLL*A EQSHPQWQPERAR*SQRTFVPTISQAGCVIPGR NKDLI*TSCKRKHRGQQRTKSN*DPHNLSCYYCP TVISSIGYK*HPQRANEYLQP*CHNPGPNQASA ESCGPVLATVSSKSSGSGASPHD**RQGSLNGR DPQAKVPAEHQTGADRHIEGGVESQQADS*GGAS *SQEQI*K*KSNGD*NHDEA*K*TEGFERRCCN LLIPESNVCNKM**ICHPVG*DAETVSSCRG*E EDSEHFVTNGYPAKTRPDPEAGGLRV*P*AVPTQ QRQTWKEQDRQP*NCQQPAASVPPQCSQLAGRQ DCPTVSPDTALPEEQPHSSSQCAPLHCLSKPPH P*SSSPVDEHLGWKFCSHTQDTAQDPAGVFFSVV RCTIGLMSIVLEDERKLRRTRSTDPDVIKHFVV SLSHR*TSAIKWLQFI*I*KKEKRNRKRVSDGW LYLDSIRET*DM*NTYIAVSSFLTLQIQLGKLIP ICLSLIFILYFICYMIYVYTNNFSEVNLIHLFS NKHNLLN*V*V*I*FEIWNWPDCGHFSC

Sequence NM_001714

ATTTCCTTCTCCCTTTCCCCGCCAGCTTCGCATCCATCTCCCCCACCCCGTAACCCCCTCCTGCCTCCATCCACCGGGGCTATGGCCGCAGAAGAGGTAT TGCAGACGGTGGACCATTATAAGACTGAGATAGAGAGGCTAACCAAGGAGCTCACGGAGACCACCCACGAGAAGATCCAGGCTGCCGAGTACGGGCTGGT GGTGCTGGAGGAGAAGCTGACCCTCAAACAGCAGTATGATGAACTGGAGGCTGAGTACGACAGCCTCAAACAGGAGCTGGAGCAGCTCAAAGAGGCATTT GGGCAGTCCTTCTCCATCCACCGGAAGGTTGCTGAAGATGGAGAGACTCGGGAGGAAACGCTTCTGCAGGAGTCAGCATCGAAGGAGGCTTACTATCTGG GGAAGATCTTGGAGATGCAGAACGAGCTGAAACAGAGCCGGGCTGTGGTCACTAATGTACAGGCAGAAAACGAGAGGCTCACCGCAGTCGTGCAGGATCT GAAGGAGAACAATGAGATGGTGGAGCTACAGAGAATACGGATGAAGGATGAAATCCGAGAATATAAGTTCCGGGAGGCACGGCTCCTTCAGGACTATACT GAATTGGAAGAAGAAAATATCACATTGCAGAAACTAGTGTCCACGTTGAAGCAGAACCAGGTTGAATACGAAGGCTTAAAGCATGAGATTAAGCGATTTG AGGAGGAGACGGTACTGCTGAACAGCCAGCTGGAAGATGCCATCCGATTGAAAGAGATTGCTGAGCACCAACTGGAAGAAGCCCTCGAGACTTTAAAAAA TGAAAGAGAGCAAAAGAACAACCTGCGGAAGGAGCTCTCCCAGTATATCAGCCTCAATGATAACCATATCAGCATCTCAGTAGATGGACTCAAATTTGCC GAGGATGGGAGTGAACCAAACAATGATGACAAAATGAACGGTCATATCCATGGGCCTCTTGTGAAACTGAATGGAGACTATCGGACTCCCACCTTAAGGA AAGGAGAGTCTCTGAACCCTGTCTCTGACTTATTCAGTGAGCTGAACATTTCAGAAATACAGAAGTTGAAGCAGCAGCTTATGCAGGTAGAGCGGGAAAA GGCCATTCTTTTGGCCAACCTACAGGAGTCACAGACACAGCTGGAACACACCAAGGGGGCACTGACGGAGCAGCATGAGCGGGTGCACCGGCTCACAGAG CACGTCAATGCCATGAGGGGCCTGCAAAGCAGCAAGGAGCTCAAGGCTGAGCTGGACGGGGAGAAGGGCCGGGACTCAGGGGAGGAGGCCCATGACTATG AGGTGGACATCAATGGTTTAGAGATCCTTGAATGCAAATACAGGGTGGCAGTAACTGAGGTGATTGATCTGAAAGCTGAAATTAAGGCCTTAAAGGAGAA ATATAATAAATCTGTAGAAAACTACACTGATGAGAAGGCCAAGTATGAGAGTAAAATCCAGATGTATGATGAGCAGGTGACAAGCCTTGAGAAGACCACC AAGGAGAGTGGTGAGAAGATGGCCCACATGGAGAAGGAGTTGCAAAAGATGACCAGCATAGCCAACGAAAATCACAGTACCCTTAATACGGCCCAGGATG AGTTAGTGACATTCAGTGAGGAGTTAGCTCAGCTTTACCACCATGTGTGTCTATGTAATAATGAAACTCCCAACAGGGTCATGCTGGATTACTATAGGCA GAGCAGAGTCACCCGCAGTGGCAGCCTGAAAGGGCCCGATGATCCCAGAGGACTTTTGTCCCCACGATTAGCCAGGCGGGGTGTGTCATCCCCGGTAGAA ACAAGGACCTCATCTGAACCAGTTGCAAAAGAAAGCACAGAGGCCAGCAAAGAACCAAGTCCAACTAAGACCCCCACAATCTCTCCTGTTATTACTGCCC CACCGTCATCTCCAGTATTGGATACAAGTGACATCCGCAAAGAGCCAATGAATATCTACAACCTTAATGCCATAATCCGGGACCAAATCAAGCATCTGCA GAAAGCTGTGGACCGGTCCTTGCAACTGTCTCGTCAAAGAGCAGCGGCTCGGGAGCTAGCCCCCATGATTGATAAAGACAAGGAAGCCTTAATGGAAGAG ATCCTCAAGCTAAAGTCCCTGCTGAGCACCAAACGGGAGCAGATCGCCACATTGAGGGCGGTGTTGAAAGCCAACAAGCAGACAGCTGAGGTGGCGCTAG CTAATCTCAAGAACAAATATGAAAATGAAAAAGCAATGGTGACTGAAACCATGACGAAGCTTAGAAATGAACTGAAGGCTTTGAAAGAAGATGCTGCAAC CTTCTCATCCCTGAGAGCAATGTTTGCAACAAGATGTGATGAATATGTCACCCAGTTGGATGAGATGCAGAGACAGTTAGCAGCTGCAGAGGATGAGAAG AAGACTCTGAACACTTTGTTACGAATGGCTATCCAGCAAAAACTCGCCCTGACCCAGAGGCTGGAGGACTTAGAGTTTGACCATGAGCAGTCCCGACGCA GCAAAGGCAAACTTGGAAAGAGCAAGATCGGCAGCCCTAAAGTAAGTGGGGAGGCATCAGTCACCGTGCCCACCATAGACACTTACCTCCTGCATAGTCA GGGCCCACAGACACCCAACATTCGGGTCAGCAGTGGCACTCAGAGGAAAAGACAATTTTCACCTTCCCTTTGTGATCAGAGCCGTCCCAGGACTTCAGGG GCTTCCTACCTACAGAATTTATTAAGAGTTCCCCCTGATCCCACCTCCACAGAATCATTTCTTCTGAAGGGCCCCCCTTCCATGAGTGAATTCATCCAAG GGCACCGGCTCAGCAAGGAAAAAAGGTTAACCGTGGCTCCACCAGATTGTCAGCAGCCTGCTGCCTCCGTACCGCCACAGTGCTCACAACTAGCCGGGAG GCAAGACTGCCCAACTGTCAGTCCTGACACAGCTCTCCCTGAGGAGCAGCCACATTCCAGCTCCCAGTGCGCCCCTCTCCACTGTCTCTCCAAGCCTCCT CACCCCTAGTCTTCATCTCCTGTGGACGAACATCTGGGGTGGAAGTTTTGTAGCCACACACAGGATACTGCCCAAGATCCAGCGGGTGTTTTCTTCTCGG TTGTTAGATGTACAATTGGATTAATGTCCATCGTTTTGGAAGACGAGAGAAAGTTGAGAAGAACACGAAGCACAGACCCTGATGTGATAAAACATTTTGT GGTTTCTCTGAGTCACAGATAAACTTCTGCCATCAAATGGCTACAGTTCATTTAAATTTAAAAAAAAGAAAAAAGAAACAGAAAACGTGTCTCAGATGGC TGGCTTTACCTCGATAGCATAAGAGAGACCTAAGACATGTAAAATACGTATATTGCAGTATCATCTTTCCTCACACTCCAAATTCAGCTAGGGAAGTTGA TTCCAATATGTTTGTCATTGATATTTATTTTGTACTTTATTTGCTACATGATTTATGTCTATACAAATAATTTCTCTGAGGTGAATTTAATTCATTTATT TTCAAATAAGCATAATTTGCTCAATTAAGTATGAGTTTGAATTTAGTTTGAAATCTGGAATTGGCCAGACTGTGGTCATTTTTCTTGCA

refseq_BICD1.F2 (forward primer)
refseq_BICD1.R2 (reverse primer)
Exon skipping and alternative donor or acceptor

Frame 0

ISFSLSPPASHPSPPPRNPLLPPSTGAMAAEEV LQTVDHYKTEIERLTKELTETTHEKIQAAEYGLV VLEEKLTLKQQYDELEAEYDSLKQELEQLKEAF GQSFSIHRKVAEDGETREETLLQESASKEAYYL GKILEMQNELKQSRAVVTNVQAENERLTAVVQDL KENNEMVELQRIRMKDEIREYKFREARLLQDYT ELEEENITLQKLVSTLKQNQVEYEGLKHEIKRF EEETVLLNSQLEDAIRLKEIAEHQLEEALETLKN EREQKNNLRKELSQYISLNDNHISISVDGLKFA EDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLR KGESLNPVSDLFSELNISEIQKLKQQLMQVEREK AILLANLQESQTQLEHTKGALTEQHERVHRLTE HVNAMRGLQSSKELKAELDGEKGRDSGEEAHDY EVDINGLEILECKYRVAVTEVIDLKAEIKALKEK YNKSVENYTDEKAKYESKIQMYDEQVTSLEKTT KESGEKMAHMEKELQKMTSIANENHSTLNTAQD ELVTFSEELAQLYHHVCLCNNETPNRVMLDYYRQ SRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVE TRTSSEPVAKESTEASKEPSPTKTPTISPVITA PPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQ KAVDRSLQLSRQRAAARELAPMIDKDKEALMEE ILKLKSLLSTKREQIATLRAVLKANKQTAEVAL ANLKNKYENEKAMVTETMTKLRNELKALKEDAAT FSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEK KTLNTLLRMAIQQKLALTQRLEDLEFDHEQSRR SKGKLGKSKIGSPKVSGEASVTVPTIDTYLLHSQ GPQTPNIRVSSGTQRKRQFSPSLCDQSRPRTSG ASYLQNLLRVPPDPTSTESFLLKGPPSMSEFIQ GHRLSKEKRLTVAPPDCQQPAASVPPQCSQLAGR QDCPTVSPDTALPEEQPHSSSQCAPLHCLSKPP HP*SSSPVDEHLGWKFCSHTQDTAQDPAGVFFS VVRCTIGLMSIVLEDERKLRRTRSTDPDVIKHFV VSLSHR*TSAIKWLQFI*I*KKEKRNRKRVSDG WLYLDSIRET*DM*NTYIAVSSFLTLQIQLGKL IPICLSLIFILYFICYMIYVYTNNFSEVNLIHLF SNKHNLLN*V*V*I*FEIWNWPDCGHFSC

Frame 1

FPSPFPRQLRIHLPHPVTPSCLHPPGLWPQKRY CRRWTIIRLR*RG*PRSSRRPPTRRSRLPSTGW WCWRRS*PSNSSMMNWRLSTTASNRSWSSSKRHL GSPSPSTGRLLKMERLGRKRFCRSQHRRRLTIW GRSWRCRTS*NRAGLWSLMYRQKTRGSPQSCRI *RRTMRWWSYREYG*RMKSENISSGRHGSFRTIL NWKKKISHCRN*CPR*SRTRLNTKA*SMRLSDL RRRRYC*TASWKMPSD*KRLLSTNWKKPSRL*K MKESKRTTCGRSSPSISASMITISASQ*MDSNLP RMGVNQTMMTK*TVISMGLL*N*METIGLPP*G KESL*TLSLTYSVS*TFQKYRS*SSSLCR*SGK RPFFWPTYRSHRHSWNTPRGH*RSSMSGCTGSQS TSMP*GACKAARSSRLSWTGRRAGTQGRRPMTM RWTSMV*RSLNANTGWQ*LR*LI*KLKLRP*RR NIINL*KTTLMRRPSMRVKSRCMMSR*QALRRPP RRVVRRWPTWRRSCKR*PA*PTKITVPLIRPRM S**HSVRS*LSFTTMCVYVIMKLPTGSCWITIG RAESPAVAA*KGPMIPEDFCPHD*PGGVCHPR*K QGPHLNQLQKKAQRPAKNQVQLRPPQSLLLLLP HRHLQYWIQVTSAKSQ*ISTTLMP*SGTKSSIC RKLWTGPCNCLVKEQRLGS*PP*LIKTRKP*WKR SSS*SPC*APNGSRSPH*GRC*KPTSRQLRWR* LISRTNMKMKKQW*LKP*RSLEMN*RL*KKMLQ PSHP*EQCLQQDVMNMSPSWMRCRDS*QLQRMRR RL*TLCYEWLSSKNSP*PRGWRT*SLTMSSPDA AKANLERARSAALK*VGRHQSPCPP*TLTSCIV RAHRHPTFGSAVALRGKDNFHLPFVIRAVPGLQG LPTYRIY*EFPLIPPPQNHFF*RAPLP*VNSSK GTGSARKKG*PWLHQIVSSLLPPYRHSAHN*PG GKTAQLSVLTQLSLRSSHIPAPSAPLSTVSPSLL TPSLHLLWTNIWGGSFVATHRILPKIQRVFSSR LLDVQLD*CPSFWKTRES*EEHEAQTLM**NIL WFL*VTDKLLPSNGYSSFKFKKKKKETENVSQMA GFTSIA*ERPKTCKIRILQYHLSSHSKFS*GS* FQYVCH*YLFCTLFAT*FMSIQIISLR*I*FIY FQISIICSIKYEFEFSLKSGIGQTVVIFLA

Frame 2

FLLPFPASFASISPTP*PPPASIHRGYGRRRGI ADGGPL*D*DREANQGAHGDHPREDPGCRVRAG GAGGEADPQTAV**TGG*VRQPQTGAGAAQRGI WAVLLHPPEGC*RWRDSGGNASAGVSIEGGLLSG EDLGDAERAETEPGCGH*CTGRKREAHRSRAGS EGEQ*DGGATENTDEG*NPRI*VPGGTAPSGLY *IGRRKYHIAETSVHVEAEPG*IRRLKA*D*AI* GGDGTAEQPAGRCHPIERDC*APTGRSPRDFKK *KRAKEQPAEGALPVYQPQ**PYQHLSRWTQIC RGWE*TKQ**QNERSYPWASCETEWRLSDSHLKE RRVSEPCL*LIQ*AEHFRNTEVEAAAYAGRAGK GHSFGQPTGVTDTAGTHQGGTDGAA*AGAPAHR ARQCHEGPAKQQGAQG*AGRGEGPGLRGGGP*L* GGHQWFRDP*MQIQGGSN*GD*SES*N*GLKGE I**ICRKLH**EGQV*E*NPDV**AGDKP*EDH QGEW*EDGPHGEGVAKDDQHSQRKSQYP*YGPG* VSDIQ*GVSSALPPCVSM***NSQQGHAGLL*A EQSHPQWQPERAR*SQRTFVPTISQAGCVIPGR NKDLI*TSCKRKHRGQQRTKSN*DPHNLSCYYCP TVISSIGYK*HPQRANEYLQP*CHNPGPNQASA ESCGPVLATVSSKSSGSGASPHD**RQGSLNGR DPQAKVPAEHQTGADRHIEGGVESQQADS*GGAS *SQEQI*K*KSNGD*NHDEA*K*TEGFERRCCN LLIPESNVCNKM**ICHPVG*DAETVSSCRG*E EDSEHFVTNGYPAKTRPDPEAGGLRV*P*AVPTQ QRQTWKEQDRQP*SKWGGISHRAHHRHLPPA*S GPTDTQHSGQQWHSEEKTIFTFPL*SEPSQDFR GFLPTEFIKSSP*SHLHRIISSEGPPFHE*IHPR APAQQGKKVNRGSTRLSAACCLRTATVLTTSRE ARLPNCQS*HSSP*GAATFQLPVRPSPLSLQAS SPLVFISCGRTSGVEVL*PHTGYCPRSSGCFLLG C*MYNWINVHRFGRREKVEKNTKHRP*CDKTFC GFSESQINFCHQMATVHLNLKKRKKKQKTCLRW LALPR*HKRDLRHVKYVYCSIIFPHTPNSAREVD SNMFVIDIYFVLYLLHDLCLYK*FL*GEFNSFI FK*A*FAQLSMSLNLV*NLELARLWSFFL