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Sequences

Sequence NM_033490

ACACAGGAAGTGAGGATACTTCTGGCGAGCGCCGGTTGCTGTTTCTTCTCAGGCTCAGGGACCGGCCGCGGCCCCGTAGGGGTGAGCGGCGGTGTTTTAA
CTCAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAAGCAGAGAT
AAAACGCTTAAAAAATTCTGATGACCGGGATTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCC
CCGTATAGAAGAGAAGACTCAATGGAAGACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATC
ACAGAAAAGATGAAAAGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCG
GAAACGACATCGAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGTGTCTGC
ACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGA
GACGGCCGGAAGCCAGTAAAAGAAGAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCG
AGTCCTCGTCAGCGGAATCAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGA
GGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTGAA
GATGAAGAACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGCAGAGGAAGAAGTGGGTG
AGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGAGCTCAAGCAGGAGCTGCCCAAGTACCT
GCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCTATGGAGTGGTCTACAGAGCAAAAGACAAGAAA
ACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCGATCACGTCCCTGAGGGAGATCAACACCATCCTCAAGGCCC
AGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACATCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCT
GATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAGGTGAAGACCCTGATGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTG
CACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCCACGCCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGG
CCTACACCCCGGTCGTGGTGACCCAGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTG
CATCTTCGGGGAGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCCCCAGTGAG
AAAATCTGGCCCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGGGCTCTGCTCT
CAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGCCTCAAGCATGAGTATTTCCGCGAGAC
CCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCAGCCCGAGGCCCCCTGAGGGAGGC
CTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACGAACCAGGGGGCCTCTGCCGCGGGCCCCGGCTTCAGCC
TCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGG
  • CDC2L1.u.f.9 (forward primer)
  • refseq_CDC2L1.R1 (reverse primer)
  • Single exon skipping

Frame 0

TQEVRILLASAGCCFFSGSGTGRGPVGVSGGVL
TQMGDEKDSWKVKTLDEILQEKKRRKEQEEKAEI
KRLKNSDDRDSKRDSLEEGELRDHCMEITIRNS
PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVH
HRKDEKRKEKCRHHSHSAEGGKHARVKEREHERR
KRHREEQDKARREWERQKRREMAREHSRRESVC
TSPNDERGLQRQSESQPLESQPASAAAGAVRVG
RRPEASKRRENGRKGPAVRLTGHQRQREEDQLGR
VLVSGIRLRF*GRRGGGGRGGGGREHQ*RIRGG
GGGRGRGGGGDRQQL*GGIRAVCRRSK*GRNE*
R*RTRK*KPPLGCSRVTVRPRFRGE*RSRGRSG*
GNAAEQRPDRGRLCARLPCPVAHRAQAGAAQVP
AGPAGLPERRGVPVPEQDRGGHLWSGLQSKRQE
NR*NCGSKAAEDGEGEGGLPDHVPEGDQHHPQGP
ASQHCHR*RDCGGQQHGQDLHRDELRGARPQEP
DGDHETALPARGGEDPDDPAAAGGETPARQLDP
AP*PQDVQPAAEPRRHPQGG*FWAGAGVRIPSEG
LHPGRGDPVVPRPRAAAWCQGILHGRGHVVSGL
HLRGAADSEASVPREFGNRSDQQSVQGAGDPQ*
ENLARLQ*APSSQKDDLQRAPLQQPPQALRGSAL
RPGLRPHEQVPDLLPREEDQR*GRPQA*VFPRD
PPPHRPLHVPHVARQERAAACEAGHQPEAP*GR
PGLQPAG*RRPEGDGLPPYHHEPGGLCRGPRLQP
QVLKVRVDPVMG

Frame 1

HRK*GYFWRAPVAVSSQAQGPAAAP*G*AAVF*
LKWVMKRTLGK*KL*MKFFRKRNEGRNKRRKQR
*NA*KILMTGIPSGIPLRRGS*EITAWRSQ*GTP
RIEEKTQWKTEEKKMILWPSNHPSKCLGKKKFI
TEKMKREKKNVGIIAIQQKGGSMLE*KKESTNV
GNDIEKNRIKLAGNGKDRREGKWQGSIPGEKVSA
HHRTMREDYSDKVKASHWSRSPPRPPRERFELG
DGRKPVKEEKMEERDLLSDLQDISDSERKTSSA
ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEE
EEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE
DEERENENHLLVVPESRFDRDSGESEEAEEEVG
EGTPQSSALTEGDYVPDSPALLPIELKQELPKYL
PALQGCRSVEEFQCLNRIEEGTYGVVYRAKDKK
TDEIVALKRLKMEKEKEGFPITSLREINTILKA
QHPNIVTVREIVVGSNMDKIYIVMNYVEHDLKSL
METMKQPFLPGEVKTLMIQLLRGVKHLHDNWIL
HRDLKTSNLLLSHAGILKVGDFGLAREYGSPLK
AYTPVVVTQWYRAPELLLGAKEYSTAVDMWSVGC
IFGELLTQKPLFPGNSEIDQINKVFKELGTPSE
KIWPGYSELPVVKKMTFSEHPYNNLRKRFGALL
SDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRET
PLPIDPSMFPTWPAKSEQQRVKRGTSPRPPEGG
LGYSQLGDDDLKETGFHLTTTNQGASAAGPGFS
LKF*RSEWTPSW

Frame 2

TGSEDTSGERRLLFLLRLRDRPRPRRGERRCFN
SNG**KGLLESENFR*NSSGKETKEGTRGESRD
KTLKKF**PGFQAGFP*GGGAERSLHGDHNKEL
PV*KRRLNGRQRRRR*FFGHQTTPANVSERKSSS
QKR*KEKRKM*AS*PFSRRGEAC*SERKRARTS
ETTSRRTG*SSPGMGKTEEKGNGKGAFQERKCL
HITER*ERTTATK*KPATGVAARLGRRGSGSSWE
TAGSQ*KKRKWKKGTCCPTYRTSATARGRPARP
SPRQRNQAQVLRKKRRRRKRRRRKGAPVKNQRR
RRRKRKRRRRRPAATLRRHQSSLPKK*VRKK*VK
MKNEKMKTTSWLFQSHGSTEIPGRVKKQRKKWV
RERRRAAP*QRATMCPTPLPCCPSSSSRSCPST
CRPCRAAGASRSSSA*TGSRRAPMEWSTEQKTRK
QMKLWL*SG*RWRRRRRASRSRP*GRSTPSSRP
SIPTLSPLERLWWAATWTRSTS**TTWSTTSRA
*WRP*NSPSCQGR*RP**SSCCGG*NTCTTTGSC
TVTSRRPTCC*ATPASSRWVILGWRGSTDPL*R
PTPRSW*PSGTAPQSCCLVPRNTPRPWTCGQWA
ASSGSC*LRSLCSPGIRKSIRSTKCSRSWGPPVR
KSGPATVSSQ*SKR*PSASTPTTTSASASGLCS
QTRASTS*TSS*PTSPGGGSALRTASSMSISAR
PPSPSTPPCSPRGPPRASSSV*SGAPARGPLREA
WATASWVTTT*RRRASTLPPRTRGPLPRAPASA
SSSEGQSGPRHG

Sequence NM_033489

ACACAGGAAGTGAGGATACTTCTGGCGAGCGCCGGTTGCTGTTTCTTCTCAGGCTCAGGGACCGGCCGCGGCCCCGTAGGGGTGAGCGGCGGTGTTTTAA
CTCAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAAGCAGAGAT
AAAACGCTTAAAAAATAACAACGCTTCTTCGGTGAAGTTCTTTTGTACTTCCAAATGTCGCAGTCTGATGACCGGGATTCCAAGCGGGATTCCCTTGAGG
AGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAGAGAAGACTCAATGGAAGACAGAGGAGAAGAAGATGATTCTTT
GGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGATGAAAAGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCA
GAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCGGAAACGACATCGAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGA
AGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGACCGCTTGGAGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCA
GAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGCGGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATG
AGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAG
TAAAAGAAGAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGA
ATCAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAA
GAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAACGAGAAA
ATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGCAGAGGAAGAAGTGGGTGAGGGAACGCCGCAGAG
CAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGAGCTCAAGCAGGAGCTGCCCAAGTACCTGCCGGCCCTGCAGGGC
TGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCTATGGAGTGGTCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGG
CTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCGATCACGTCCCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGT
CACCGTTAGAGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACATCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAA
CAGCCCTTCCTGCCAGGGGAGGTGAAGACCCTGATGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGA
CGTCCAACCTGCTGCTGAGCCACGCCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGT
GGTGACCCAGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTGCATCTTCGGGGAGCTG
CTGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCCCCAGTGAGAAAATCTGGCCCGGCT
ACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGGGCTCTGCTCTCAGACCAGGGCTTCGA
CCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGCCTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGAC
CCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCAGCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGC
TGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACGAACCAGGGGGCCTCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGAAGGTC
AGAGTGGACCCCGTCATGGGG
  • CDC2L1.u.f.9 (forward primer)
  • refseq_CDC2L1.R1 (reverse primer)
  • Single exon skipping

Frame 0

TQEVRILLASAGCCFFSGSGTGRGPVGVSGGVL
TQMGDEKDSWKVKTLDEILQEKKRRKEQEEKAEI
KRLKNNNASSVKFFCTSKCRSLMTGIPSGIPLR
RGS*EITAWRSQ*GTPRIEEKTQWKTEEKKMIL
WPSNHPSKCLGKKKFITEKMKREKKNVGIIAIQQ
KGGSMLE*KKESTNVGNDIEKNRIKLAGNGKDR
REGKWQGSIPGEKGTAWSS*KGSGSGSARCGSS
RRSSGSRRSASGGRRSGARSGRPAGKCLHITER*
ERTTATK*KPATGVAARLGRRGSGSSWETAGSQ
*KKRKWKKGTCCPTYRTSATARGRPARPSPRQR
NQAQVLRKKRRRRKRRRRKGAPVKNQRRRRRKRK
RRRRRPAATLRRHQSSLPKK*VRKK*VKMKNEK
MKTTSWLFQSHGSTEIPGRVKKQRKKWVRERRR
AAP*QRATMCPTPLPCCPSSSSRSCPSTCRPCRA
AGASRSSSA*TGSRRAPMEWSTEQKTRKQMKLW
L*SG*RWRRRRRASRSRP*GRSTPSSRPSIPTL
SPLERLWWAATWTRSTS**TTWSTTSRA*WRP*N
SPSCQGR*RP**SSCCGG*NTCTTTGSCTVTSR
RPTCC*ATPASSRWVILGWRGSTDPL*RPTPRS
W*PSGTAPQSCCLVPRNTPRPWTCGQWAASSGSC
*LRSLCSPGIRKSIRSTKCSRSWGPPVRKSGPA
TVSSQ*SKR*PSASTPTTTSASASGLCSQTRAS
TS*TSS*PTSPGGGSALRTASSMSISARPPSPST
PPCSPRGPPRASSSV*SGAPARGPLREAWATAS
WVTTT*RRRASTLPPRTRGPLPRAPASASSSEG
QSGPRHG

Frame 1

HRK*GYFWRAPVAVSSQAQGPAAAP*G*AAVF*
LKWVMKRTLGK*KL*MKFFRKRNEGRNKRRKQR
*NA*KITTLLR*SSFVLPNVAV**PGFQAGFP*G
GGAERSLHGDHNKELPV*KRRLNGRQRRRR*FF
GHQTTPANVSERKSSSQKR*KEKRKM*AS*PFS
RRGEAC*SERKRARTSETTSRRTG*SSPGMGKTE
EKGNGKGAFQERKGPLGAVRKEAGAGAQDAGAA
EGAAGAEGARAAGGGAAQGAGGPQGSVCTSPND
ERGLQRQSESQPLESQPASAAAGAVRVGRRPEAS
KRRENGRKGPAVRLTGHQRQREEDQLGRVLVSG
IRLRF*GRRGGGGRGGGGREHQ*RIRGGGGGRG
RGGGGDRQQL*GGIRAVCRRSK*GRNE*R*RTRK
*KPPLGCSRVTVRPRFRGE*RSRGRSG*GNAAE
QRPDRGRLCARLPCPVAHRAQAGAAQVPAGPAG
LPERRGVPVPEQDRGGHLWSGLQSKRQENR*NCG
SKAAEDGEGEGGLPDHVPEGDQHHPQGPASQHC
HR*RDCGGQQHGQDLHRDELRGARPQEPDGDHE
TALPARGGEDPDDPAAAGGETPARQLDPAP*PQD
VQPAAEPRRHPQGG*FWAGAGVRIPSEGLHPGR
GDPVVPRPRAAAWCQGILHGRGHVVSGLHLRGA
ADSEASVPREFGNRSDQQSVQGAGDPQ*ENLARL
Q*APSSQKDDLQRAPLQQPPQALRGSALRPGLR
PHEQVPDLLPREEDQR*GRPQA*VFPRDPPPHR
PLHVPHVARQERAAACEAGHQPEAP*GRPGLQPA
G*RRPEGDGLPPYHHEPGGLCRGPRLQPQVLKV
RVDPVMG

Frame 2

TGSEDTSGERRLLFLLRLRDRPRPRRGERRCFN
SNG**KGLLESENFR*NSSGKETKEGTRGESRD
KTLKK*QRFFGEVLLYFQMSQSDDRDSKRDSLE
EGELRDHCMEITIRNSPYRREDSMEDRGEEDDSL
AIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSA
EGGKHARVKEREHERRKRHREEQDKARREWERQ
KRREMAREHSRRERDRLEQLERKRERERKMREQQ
KEQREQKERERRAEERRKEREARREVSAHHRTM
REDYSDKVKASHWSRSPPRPPRERFELGDGRKP
VKEEKMEERDLLSDLQDISDSERKTSSAESSSAE
SGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE
EEEEETGSNSEEASEQSAEEVSEEEMSEDEERE
NENHLLVVPESRFDRDSGESEEAEEEVGEGTPQS
SALTEGDYVPDSPALLPIELKQELPKYLPALQG
CRSVEEFQCLNRIEEGTYGVVYRAKDKKTDEIV
ALKRLKMEKEKEGFPITSLREINTILKAQHPNIV
TVREIVVGSNMDKIYIVMNYVEHDLKSLMETMK
QPFLPGEVKTLMIQLLRGVKHLHDNWILHRDLK
TSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVV
VTQWYRAPELLLGAKEYSTAVDMWSVGCIFGEL
LTQKPLFPGNSEIDQINKVFKELGTPSEKIWPG
YSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFD
LMNKFLTYFPGRRISAEDGLKHEYFRETPLPID
PSMFPTWPAKSEQQRVKRGTSPRPPEGGLGYSQ
LGDDDLKETGFHLTTTNQGASAAGPGFSLKF*RS
EWTPSW

Sequence NM_001787

ACACAGGAAGTGAGGATACTTCTGGCGAGCGCCGGTTGCTGTTTCTTCTCAGGCTCAGGGACCGGCCGCGGCCCCGTAGGGGTGAGCGGCGGTGTTTTAA
CTCAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAAGCAGAGAT
AAAACGCTTAAAAAATTCTGATGACCGGGATTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCC
CCGTATAGAAGAGAAGACTCAATGGAAGACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATC
ACAGAAAAGATGAAAAGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCG
GAAACGACATCGAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGACCGC
TTGGAGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGC
GGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGGAGTCGCAG
CCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGGTGAGGCCAGGCCGGCGCCTGCGCAGAAGCCAGCACAGTTAAAAGAA
GAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCT
CAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAGAGGAGGA
GGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAACGAGAAAATGAAAAC
CACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGCAGAGGAAGAAGTGGGTGAGGGAACGCCGCAGAGCAGCGCCC
TGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGAGCTCAAGCAGGAGCTGCCCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAG
CGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCTATGGAGTGGTCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAG
CGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCGATCACGTCCCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTA
GAGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACATCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTT
CCTGCCAGGGGAGGTGAAGACCCTGATGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAAC
CTGCTGCTGAGCCACGCCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTGGTGACCC
AGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTGCATCTTCGGGGAGCTGCTGACTCA
GAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCCCCAGTGAGAAAATCTGGCCCGGCTACAGTGAG
CTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGGGCTCTGCTCTCAGACCAGGGCTTCGACCTCATGA
ACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGCCTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCAT
GTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCAGCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGAC
GACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACGAACCAGGGGGCCTCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGA
CCCCGTCATGGGG
  • CDC2L1.u.f.9 (forward primer)
  • refseq_CDC2L1.R1 (reverse primer)
  • Single exon skipping

Frame 0

TQEVRILLASAGCCFFSGSGTGRGPVGVSGGVL
TQMGDEKDSWKVKTLDEILQEKKRRKEQEEKAEI
KRLKNSDDRDSKRDSLEEGELRDHCMEITIRNS
PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVH
HRKDEKRKEKCRHHSHSAEGGKHARVKEREHERR
KRHREEQDKARREWERQKRREMAREHSRRERDR
LEQLERKRERERKMREQQKEQREQKERERRAEE
RRKEREARREVSAHHRTMREDYSDKVKASHWSRS
PPRPPRERFELGDGRKPGEARPAPAQKPAQLKE
EKMEERDLLSDLQDISDSERKTSSAESSSAESG
SGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEE
EETGSNSEEASEQSAEEVSEEEMSEDEERENEN
HLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA
LTEGDYVPDSPALLPIELKQELPKYLPALQGCRS
VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALK
RLKMEKEKEGFPITSLREINTILKAQHPNIVTV
REIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPF
LPGEVKTLMIQLLRGVKHLHDNWILHRDLKTSN
LLLSHAGILKVGDFGLAREYGSPLKAYTPVVVT
QWYRAPELLLGAKEYSTAVDMWSVGCIFGELLTQ
KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSE
LPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLM
NKFLTYFPGRRISAEDGLKHEYFRETPLPIDPSM
FPTWPAKSEQQRVKRGTSPRPPEGGLGYSQLGD
DDLKETGFHLTTTNQGASAAGPGFSLKF*RSEW
TPSW

Frame 1

HRK*GYFWRAPVAVSSQAQGPAAAP*G*AAVF*
LKWVMKRTLGK*KL*MKFFRKRNEGRNKRRKQR
*NA*KILMTGIPSGIPLRRGS*EITAWRSQ*GTP
RIEEKTQWKTEEKKMILWPSNHPSKCLGKKKFI
TEKMKREKKNVGIIAIQQKGGSMLE*KKESTNV
GNDIEKNRIKLAGNGKDRREGKWQGSIPGEKGTA
WSS*KGSGSGSARCGSSRRSSGSRRSASGGRRS
GARSGRPAGKCLHITER*ERTTATK*KPATGVA
ARLGRRGSGSSWETAGSQVRPGRRLRRSQHS*KK
RKWKKGTCCPTYRTSATARGRPARPSPRQRNQA
QVLRKKRRRRKRRRRKGAPVKNQRRRRRKRKRR
RRRPAATLRRHQSSLPKK*VRKK*VKMKNEKMKT
TSWLFQSHGSTEIPGRVKKQRKKWVRERRRAAP
*QRATMCPTPLPCCPSSSSRSCPSTCRPCRAAG
ASRSSSA*TGSRRAPMEWSTEQKTRKQMKLWL*S
G*RWRRRRRASRSRP*GRSTPSSRPSIPTLSPL
ERLWWAATWTRSTS**TTWSTTSRA*WRP*NSP
SCQGR*RP**SSCCGG*NTCTTTGSCTVTSRRPT
CC*ATPASSRWVILGWRGSTDPL*RPTPRSW*P
SGTAPQSCCLVPRNTPRPWTCGQWAASSGSC*L
RSLCSPGIRKSIRSTKCSRSWGPPVRKSGPATVS
SQ*SKR*PSASTPTTTSASASGLCSQTRASTS*
TSS*PTSPGGGSALRTASSMSISARPPSPSTPP
CSPRGPPRASSSV*SGAPARGPLREAWATASWVT
TT*RRRASTLPPRTRGPLPRAPASASSSEGQSG
PRHG

Frame 2

TGSEDTSGERRLLFLLRLRDRPRPRRGERRCFN
SNG**KGLLESENFR*NSSGKETKEGTRGESRD
KTLKKF**PGFQAGFP*GGGAERSLHGDHNKEL
PV*KRRLNGRQRRRR*FFGHQTTPANVSERKSSS
QKR*KEKRKM*AS*PFSRRGEAC*SERKRARTS
ETTSRRTG*SSPGMGKTEEKGNGKGAFQERKGP
LGAVRKEAGAGAQDAGAAEGAAGAEGARAAGGGA
AQGAGGPQGSVCTSPNDERGLQRQSESQPLESQ
PASAAAGAVRVGRRPEAR*GQAGACAEASTVKR
RENGRKGPAVRLTGHQRQREEDQLGRVLVSGIRL
RF*GRRGGGGRGGGGREHQ*RIRGGGGGRGRGG
GGDRQQL*GGIRAVCRRSK*GRNE*R*RTRK*K
PPLGCSRVTVRPRFRGE*RSRGRSG*GNAAEQRP
DRGRLCARLPCPVAHRAQAGAAQVPAGPAGLPE
RRGVPVPEQDRGGHLWSGLQSKRQENR*NCGSK
AAEDGEGEGGLPDHVPEGDQHHPQGPASQHCHR*
RDCGGQQHGQDLHRDELRGARPQEPDGDHETAL
PARGGEDPDDPAAAGGETPARQLDPAP*PQDVQ
PAAEPRRHPQGG*FWAGAGVRIPSEGLHPGRGDP
VVPRPRAAAWCQGILHGRGHVVSGLHLRGAADS
EASVPREFGNRSDQQSVQGAGDPQ*ENLARLQ*
APSSQKDDLQRAPLQQPPQALRGSALRPGLRPHE
QVPDLLPREEDQR*GRPQA*VFPRDPPPHRPLH
VPHVARQERAAACEAGHQPEAP*GRPGLQPAG*
RRPEGDGLPPYHHEPGGLCRGPRLQPQVLKVRVD
PVMG

Sequence NM_033486

ACACAGGAAGTGAGGATACTTCTGGCGAGCGCCGGTTGCTGTTTCTTCTCAGGCTCAGGGACCGGCCGCGGCCCCGTAGGGGTGAGCGGCGGTGTTTTAA
CTCAAATGGGTGATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAAGCAGAGAT
AAAACGCTTAAAAAATTCTGATGACCGGGATTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCC
CCGTATAGAAGAGAAGACTCAATGGAAGACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATC
ACAGAAAAGATGAAAAGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCG
GAAACGACATCGAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGACCGC
TTGGAGCAGTTAGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGC
GGCGCAAGGAGCGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGGAGTCGCAG
CCCGCCTCGGCCGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAAAGAAGAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTACAG
GACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGG
AGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCA
GTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGAT
TCCGGGGAGAGTGAAGAAGCAGAGGAAGAAGTGGGTGAGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGT
TGCCCATCGAGCTCAAGCAGGAGCTGCCCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGG
CACCTATGGAGTGGTCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCGATC
ACGTCCCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACA
TCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAGGTGAAGACCCTGATGATCCAGCTGCT
GCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCCACGCCGGCATCCTCAAGGTGGGTGAT
TTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTGGTGACCCAGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGG
AATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTGCATCTTCGGGGAGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGAT
CAACAAAGTGTTCAAGGAGCTGGGGACCCCCAGTGAGAAAATCTGGCCCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCC
TACAACAACCTCCGCAAGCGCTTCGGGGCTCTGCTCTCAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCG
CTGAGGACGGCCTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGT
GAAGCGGGGCACCAGCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACG
AACCAGGGGGCCTCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGG
  • CDC2L1.u.f.9 (forward primer)
  • refseq_CDC2L1.R1 (reverse primer)
  • Single exon skipping

Frame 0

TQEVRILLASAGCCFFSGSGTGRGPVGVSGGVL
TQMGDEKDSWKVKTLDEILQEKKRRKEQEEKAEI
KRLKNSDDRDSKRDSLEEGELRDHCMEITIRNS
PYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVH
HRKDEKRKEKCRHHSHSAEGGKHARVKEREHERR
KRHREEQDKARREWERQKRREMAREHSRRERDR
LEQLERKRERERKMREQQKEQREQKERERRAEE
RRKEREARREVSAHHRTMREDYSDKVKASHWSRS
PPRPPRERFELGDGRKPVKEEKMEERDLLSDLQ
DISDSERKTSSAESSSAESGSGSEEEEEEEEEE
EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQ
SAEEVSEEEMSEDEERENENHLLVVPESRFDRD
SGESEEAEEEVGEGTPQSSALTEGDYVPDSPAL
LPIELKQELPKYLPALQGCRSVEEFQCLNRIEEG
TYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPI
TSLREINTILKAQHPNIVTVREIVVGSNMDKIY
IVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLL
RGVKHLHDNWILHRDLKTSNLLLSHAGILKVGD
FGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK
EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQI
NKVFKELGTPSEKIWPGYSELPVVKKMTFSEHP
YNNLRKRFGALLSDQGFDLMNKFLTYFPGRRIS
AEDGLKHEYFRETPLPIDPSMFPTWPAKSEQQRV
KRGTSPRPPEGGLGYSQLGDDDLKETGFHLTTT
NQGASAAGPGFSLKF*RSEWTPSW

Frame 1

HRK*GYFWRAPVAVSSQAQGPAAAP*G*AAVF*
LKWVMKRTLGK*KL*MKFFRKRNEGRNKRRKQR
*NA*KILMTGIPSGIPLRRGS*EITAWRSQ*GTP
RIEEKTQWKTEEKKMILWPSNHPSKCLGKKKFI
TEKMKREKKNVGIIAIQQKGGSMLE*KKESTNV
GNDIEKNRIKLAGNGKDRREGKWQGSIPGEKGTA
WSS*KGSGSGSARCGSSRRSSGSRRSASGGRRS
GARSGRPAGKCLHITER*ERTTATK*KPATGVA
ARLGRRGSGSSWETAGSQ*KKRKWKKGTCCPTYR
TSATARGRPARPSPRQRNQAQVLRKKRRRRKRR
RRKGAPVKNQRRRRRKRKRRRRRPAATLRRHQS
SLPKK*VRKK*VKMKNEKMKTTSWLFQSHGSTEI
PGRVKKQRKKWVRERRRAAP*QRATMCPTPLPC
CPSSSSRSCPSTCRPCRAAGASRSSSA*TGSRR
APMEWSTEQKTRKQMKLWL*SG*RWRRRRRASRS
RP*GRSTPSSRPSIPTLSPLERLWWAATWTRST
S**TTWSTTSRA*WRP*NSPSCQGR*RP**SSC
CGG*NTCTTTGSCTVTSRRPTCC*ATPASSRWVI
LGWRGSTDPL*RPTPRSW*PSGTAPQSCCLVPR
NTPRPWTCGQWAASSGSC*LRSLCSPGIRKSIR
STKCSRSWGPPVRKSGPATVSSQ*SKR*PSASTP
TTTSASASGLCSQTRASTS*TSS*PTSPGGGSA
LRTASSMSISARPPSPSTPPCSPRGPPRASSSV
*SGAPARGPLREAWATASWVTTT*RRRASTLPPR
TRGPLPRAPASASSSEGQSGPRHG

Frame 2

TGSEDTSGERRLLFLLRLRDRPRPRRGERRCFN
SNG**KGLLESENFR*NSSGKETKEGTRGESRD
KTLKKF**PGFQAGFP*GGGAERSLHGDHNKEL
PV*KRRLNGRQRRRR*FFGHQTTPANVSERKSSS
QKR*KEKRKM*AS*PFSRRGEAC*SERKRARTS
ETTSRRTG*SSPGMGKTEEKGNGKGAFQERKGP
LGAVRKEAGAGAQDAGAAEGAAGAEGARAAGGGA
AQGAGGPQGSVCTSPNDERGLQRQSESQPLESQ
PASAAAGAVRVGRRPEASKRRENGRKGPAVRLT
GHQRQREEDQLGRVLVSGIRLRF*GRRGGGGRGG
GGREHQ*RIRGGGGGRGRGGGGDRQQL*GGIRA
VCRRSK*GRNE*R*RTRK*KPPLGCSRVTVRPR
FRGE*RSRGRSG*GNAAEQRPDRGRLCARLPCPV
AHRAQAGAAQVPAGPAGLPERRGVPVPEQDRGG
HLWSGLQSKRQENR*NCGSKAAEDGEGEGGLPD
HVPEGDQHHPQGPASQHCHR*RDCGGQQHGQDLH
RDELRGARPQEPDGDHETALPARGGEDPDDPAA
AGGETPARQLDPAP*PQDVQPAAEPRRHPQGG*
FWAGAGVRIPSEGLHPGRGDPVVPRPRAAAWCQG
ILHGRGHVVSGLHLRGAADSEASVPREFGNRSD
QQSVQGAGDPQ*ENLARLQ*APSSQKDDLQRAP
LQQPPQALRGSALRPGLRPHEQVPDLLPREEDQR
*GRPQA*VFPRDPPPHRPLHVPHVARQERAAAC
EAGHQPEAP*GRPGLQPAG*RRPEGDGLPPYHH
EPGGLCRGPRLQPQVLKVRVDPVMG

Sequence NM_024011

ACACAGGAAGTGAGGATACTTCTGGCGAGCGCCGGTTGCTGTTTCTTCTCAGGCTCAGGGACCGGCCGCGGCCCCGTAGGGTGTTTTAACTCAAATGGGT
GATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAAGCAGAGATAAAACGCTTAA
AAAATTCTGATGACCGGGATTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAG
AGAAGACTCAATGGAAGACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGAT
GAAAAGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCGGAAACGACATC
GAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGACCGCTTGGAGCAGTT
AGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGCGGCGCAAGGAG
CGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGC
CGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAAAGAAGAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGA
CAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGG
AGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAG
AAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAG
TGAAGAAGCAGAGGAAGAAGTGGGTGAGGGAACGCCGCAGAGCAGCGCCCTGACAGAGGGCGACTATGTGCCCGACTCCCCTGCCCTGTTGCCCATCGAG
CTCAAGCAGGAGCTGCCCAAGTACCTGCCGGCCCTGCAGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCTATGGAG
TGGTCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCGATCACGTCCCTGAG
GGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACATCGTGATGAAC
TACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAGGTGAAGACCCTGATGATCCAGCTGCTGCGGGGGGTGA
AACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCCACGCCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGC
GCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTGGTGACCCAGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACG
GCCGTGGACATGTGGTCAGTGGGCTGCATCTTCGGGGAGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGT
TCAAGGAGCTGGGGACCCCCAGTGAGAAAATCTGGCCCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCT
CCGCAAGCGCTTCGGGGCTCTGCTCTCAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGC
CTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCA
CCAGCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACGAACCAGGGGGC
CTCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGG
  • CDC2L1.u.f.9 (forward primer)
  • refseq_CDC2L1.R1 (reverse primer)
  • Single exon skipping

Frame 0

TQEVRILLASAGCCFFSGSGTGRGPVGCFNSNG
**KGLLESENFR*NSSGKETKEGTRGESRDKTLK
KF**PGFQAGFP*GGGAERSLHGDHNKELPV*K
RRLNGRQRRRR*FFGHQTTPANVSERKSSSQKR
*KEKRKM*AS*PFSRRGEAC*SERKRARTSETTS
RRTG*SSPGMGKTEEKGNGKGAFQERKGPLGAV
RKEAGAGAQDAGAAEGAAGAEGARAAGGGAAQG
AGGPQGSVCTSPNDERGLQRQSESQPLESQPASA
AAGAVRVGRRPEASKRRENGRKGPAVRLTGHQR
QREEDQLGRVLVSGIRLRF*GRRGGGGRGGGGR
EHQ*RIRGGGGGRGRGGGGDRQQL*GGIRAVCRR
SK*GRNE*R*RTRK*KPPLGCSRVTVRPRFRGE
*RSRGRSG*GNAAEQRPDRGRLCARLPCPVAHR
AQAGAAQVPAGPAGLPERRGVPVPEQDRGGHLWS
GLQSKRQENR*NCGSKAAEDGEGEGGLPDHVPE
GDQHHPQGPASQHCHR*RDCGGQQHGQDLHRDE
LRGARPQEPDGDHETALPARGGEDPDDPAAAGGE
TPARQLDPAP*PQDVQPAAEPRRHPQGG*FWAG
AGVRIPSEGLHPGRGDPVVPRPRAAAWCQGILH
GRGHVVSGLHLRGAADSEASVPREFGNRSDQQSV
QGAGDPQ*ENLARLQ*APSSQKDDLQRAPLQQP
PQALRGSALRPGLRPHEQVPDLLPREEDQR*GR
PQA*VFPRDPPPHRPLHVPHVARQERAAACEAGH
QPEAP*GRPGLQPAG*RRPEGDGLPPYHHEPGG
LCRGPRLQPQVLKVRVDPVMG

Frame 1

HRK*GYFWRAPVAVSSQAQGPAAAP*GVLTQMG
DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRL
KNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRR
EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKD
EKRKEKCRHHSHSAEGGKHARVKEREHERRKRH
REEQDKARREWERQKRREMAREHSRRERDRLEQL
ERKRERERKMREQQKEQREQKERERRAEERRKE
REARREVSAHHRTMREDYSDKVKASHWSRSPPR
PPRERFELGDGRKPVKEEKMEERDLLSDLQDISD
SERKTSSAESSSAESGSGSEEEEEEEEEEEEEG
STSEESEEEEEEEEEEEEETGSNSEEASEQSAE
EVSEEEMSEDEERENENHLLVVPESRFDRDSGES
EEAEEEVGEGTPQSSALTEGDYVPDSPALLPIE
LKQELPKYLPALQGCRSVEEFQCLNRIEEGTYG
VVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLR
EINTILKAQHPNIVTVREIVVGSNMDKIYIVMN
YVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGV
KHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLA
REYGSPLKAYTPVVVTQWYRAPELLLGAKEYST
AVDMWSVGCIFGELLTQKPLFPGNSEIDQINKV
FKELGTPSEKIWPGYSELPVVKKMTFSEHPYNNL
RKRFGALLSDQGFDLMNKFLTYFPGRRISAEDG
LKHEYFRETPLPIDPSMFPTWPAKSEQQRVKRG
TSPRPPEGGLGYSQLGDDDLKETGFHLTTTNQGA
SAAGPGFSLKF*RSEWTPSW

Frame 2

TGSEDTSGERRLLFLLRLRDRPRPRRVF*LKWV
MKRTLGK*KL*MKFFRKRNEGRNKRRKQR*NA*
KILMTGIPSGIPLRRGS*EITAWRSQ*GTPRIE
EKTQWKTEEKKMILWPSNHPSKCLGKKKFITEKM
KREKKNVGIIAIQQKGGSMLE*KKESTNVGNDI
EKNRIKLAGNGKDRREGKWQGSIPGEKGTAWSS
*KGSGSGSARCGSSRRSSGSRRSASGGRRSGARS
GRPAGKCLHITER*ERTTATK*KPATGVAARLG
RRGSGSSWETAGSQ*KKRKWKKGTCCPTYRTSA
TARGRPARPSPRQRNQAQVLRKKRRRRKRRRRKG
APVKNQRRRRRKRKRRRRRPAATLRRHQSSLPK
K*VRKK*VKMKNEKMKTTSWLFQSHGSTEIPGR
VKKQRKKWVRERRRAAP*QRATMCPTPLPCCPSS
SSRSCPSTCRPCRAAGASRSSSA*TGSRRAPME
WSTEQKTRKQMKLWL*SG*RWRRRRRASRSRP*
GRSTPSSRPSIPTLSPLERLWWAATWTRSTS**T
TWSTTSRA*WRP*NSPSCQGR*RP**SSCCGG*
NTCTTTGSCTVTSRRPTCC*ATPASSRWVILGW
RGSTDPL*RPTPRSW*PSGTAPQSCCLVPRNTPR
PWTCGQWAASSGSC*LRSLCSPGIRKSIRSTKC
SRSWGPPVRKSGPATVSSQ*SKR*PSASTPTTT
SASASGLCSQTRASTS*TSS*PTSPGGGSALRTA
SSMSISARPPSPSTPPCSPRGPPRASSSV*SGA
PARGPLREAWATASWVTTT*RRRASTLPPRTRG
PLPRAPASASSSEGQSGPRHG

Sequence NM_033527

ACACAGGAAGTGAGGATACTTCTGGCGAGCGCCGGTTGCTGTTTCTTCTCAGGCTCAGGGACCGGCCGCGGCCCCGTAGGGTGTTTTAACTCAAATGGGT
GATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAAGCAGAGATAAAACGCTTAA
AAAATTCTGATGACCGGGATTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAG
AGAAGACTCAATGGAAGACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGAT
GAAAAGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCGGAAACGACATC
GAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGACCGCTTGGAGCAGTT
AGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGCGGCGCAAGGAG
CGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGC
CGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGTAAAAGAAGAGAAAATGGAAGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGA
CAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCTCAGGTTCTGAGGAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGG
AGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGACCGGCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAG
AAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAACGAGAAAATGAAAACCACCTCTTGGTTGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAG
TGAAGAAGCAGAGGAAGAAGTGGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAGGATCGAGGAGGGCACCTATGGAGTGGTCTACAGAGCAAA
AGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAGGGCTTCCCGATCACGTCCCTGAGGGAGATCAACACCATC
CTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACATGGACAAGATCTACATCGTGATGAACTACGTGGAGCACGACC
TCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAGGTGAAGACCCTGATGATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAA
CTGGATCCTGCACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCCACGCCGGCATCCTCAAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCC
CCTCTGAAGGCCTACACCCCGGTCGTGGTGACCCAGTGGTACCGCGCCCCAGAGCTGCTGCTTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGT
CAGTGGGCTGCATCTTCGGGGAGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGAAATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGAC
CCCCAGTGAGAAAATCTGGCCCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTCAGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGG
GCTCTGCTCTCAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGAGGAGGATCAGCGCTGAGGACGGCCTCAAGCATGAGTATT
TCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGAGCAGCAGCGTGTGAAGCGGGGCACCAGCCCGAGGCCCCC
TGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCACCTTACCACCACGAACCAGGGGGCCTCTGCCGCGGGCCCC
GGCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGG
  • CDC2L1.u.f.9 (forward primer)
  • refseq_CDC2L1.R1 (reverse primer)
  • Single exon skipping

Frame 0

TQEVRILLASAGCCFFSGSGTGRGPVGCFNSNG
**KGLLESENFR*NSSGKETKEGTRGESRDKTLK
KF**PGFQAGFP*GGGAERSLHGDHNKELPV*K
RRLNGRQRRRR*FFGHQTTPANVSERKSSSQKR
*KEKRKM*AS*PFSRRGEAC*SERKRARTSETTS
RRTG*SSPGMGKTEEKGNGKGAFQERKGPLGAV
RKEAGAGAQDAGAAEGAAGAEGARAAGGGAAQG
AGGPQGSVCTSPNDERGLQRQSESQPLESQPASA
AAGAVRVGRRPEASKRRENGRKGPAVRLTGHQR
QREEDQLGRVLVSGIRLRF*GRRGGGGRGGGGR
EHQ*RIRGGGGGRGRGGGGDRQQL*GGIRAVCRR
SK*GRNE*R*RTRK*KPPLGCSRVTVRPRFRGE
*RSRGRSGAAGASRSSSA*TGSRRAPMEWSTEQ
KTRKQMKLWL*SG*RWRRRRRASRSRP*GRSTPS
SRPSIPTLSPLERLWWAATWTRSTS**TTWSTT
SRA*WRP*NSPSCQGR*RP**SSCCGG*NTCTT
TGSCTVTSRRPTCC*ATPASSRWVILGWRGSTDP
L*RPTPRSW*PSGTAPQSCCLVPRNTPRPWTCG
QWAASSGSC*LRSLCSPGIRKSIRSTKCSRSWG
PPVRKSGPATVSSQ*SKR*PSASTPTTTSASASG
LCSQTRASTS*TSS*PTSPGGGSALRTASSMSI
SARPPSPSTPPCSPRGPPRASSSV*SGAPARGP
LREAWATASWVTTT*RRRASTLPPRTRGPLPRAP
ASASSSEGQSGPRHG

Frame 1

HRK*GYFWRAPVAVSSQAQGPAAAP*GVLTQMG
DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRL
KNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRR
EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKD
EKRKEKCRHHSHSAEGGKHARVKEREHERRKRH
REEQDKARREWERQKRREMAREHSRRERDRLEQL
ERKRERERKMREQQKEQREQKERERRAEERRKE
REARREVSAHHRTMREDYSDKVKASHWSRSPPR
PPRERFELGDGRKPVKEEKMEERDLLSDLQDISD
SERKTSSAESSSAESGSGSEEEEEEEEEEEEEG
STSEESEEEEEEEEEEEEETGSNSEEASEQSAE
EVSEEEMSEDEERENENHLLVVPESRFDRDSGES
EEAEEEVGLPERRGVPVPEQDRGGHLWSGLQSK
RQENR*NCGSKAAEDGEGEGGLPDHVPEGDQHH
PQGPASQHCHR*RDCGGQQHGQDLHRDELRGARP
QEPDGDHETALPARGGEDPDDPAAAGGETPARQ
LDPAP*PQDVQPAAEPRRHPQGG*FWAGAGVRI
PSEGLHPGRGDPVVPRPRAAAWCQGILHGRGHVV
SGLHLRGAADSEASVPREFGNRSDQQSVQGAGD
PQ*ENLARLQ*APSSQKDDLQRAPLQQPPQALR
GSALRPGLRPHEQVPDLLPREEDQR*GRPQA*VF
PRDPPPHRPLHVPHVARQERAAACEAGHQPEAP
*GRPGLQPAG*RRPEGDGLPPYHHEPGGLCRGP
RLQPQVLKVRVDPVMG

Frame 2

TGSEDTSGERRLLFLLRLRDRPRPRRVF*LKWV
MKRTLGK*KL*MKFFRKRNEGRNKRRKQR*NA*
KILMTGIPSGIPLRRGS*EITAWRSQ*GTPRIE
EKTQWKTEEKKMILWPSNHPSKCLGKKKFITEKM
KREKKNVGIIAIQQKGGSMLE*KKESTNVGNDI
EKNRIKLAGNGKDRREGKWQGSIPGEKGTAWSS
*KGSGSGSARCGSSRRSSGSRRSASGGRRSGARS
GRPAGKCLHITER*ERTTATK*KPATGVAARLG
RRGSGSSWETAGSQ*KKRKWKKGTCCPTYRTSA
TARGRPARPSPRQRNQAQVLRKKRRRRKRRRRKG
APVKNQRRRRRKRKRRRRRPAATLRRHQSSLPK
K*VRKK*VKMKNEKMKTTSWLFQSHGSTEIPGR
VKKQRKKWGCRSVEEFQCLNRIEEGTYGVVYRAK
DKKTDEIVALKRLKMEKEKEGFPITSLREINTI
LKAQHPNIVTVREIVVGSNMDKIYIVMNYVEHD
LKSLMETMKQPFLPGEVKTLMIQLLRGVKHLHDN
WILHRDLKTSNLLLSHAGILKVGDFGLAREYGS
PLKAYTPVVVTQWYRAPELLLGAKEYSTAVDMW
SVGCIFGELLTQKPLFPGNSEIDQINKVFKELGT
PSEKIWPGYSELPVVKKMTFSEHPYNNLRKRFG
ALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEY
FRETPLPIDPSMFPTWPAKSEQQRVKRGTSPRPP
EGGLGYSQLGDDDLKETGFHLTTTNQGASAAGP
GFSLKF*RSEWTPSW

Sequence NM_033532

ACACAGGAAGTGAGGATACTTCTGGCGAGCGCCGGTTGCTGTTTCTTCTCAGGCTCAGGGACCGGCCGCGGCCCCGTAGGGTGTTTTAACTCAAATGGGT
GATGAAAAGGACTCTTGGAAAGTGAAAACTTTAGATGAAATTCTTCAGGAAAAGAAACGAAGGAAGGAACAAGAGGAGAAAGCAGAGATAAAACGCTTAA
AAAATTCTGATGACCGGGATTCCAAGCGGGATTCCCTTGAGGAGGGGGAGCTGAGAGATCACTGCATGGAGATCACAATAAGGAACTCCCCGTATAGAAG
AGAAGACTCAATGGAAGACAGAGGAGAAGAAGATGATTCTTTGGCCATCAAACCACCCCAGCAAATGTCTCGGAAAGAAAAAGTTCATCACAGAAAAGAT
GAAAAGAGAAAAGAAAAATGTAGGCATCATAGCCATTCAGCAGAAGGGGGGAAGCATGCTAGAGTGAAAGAAAGAGAGCACGAACGTCGGAAACGACATC
GAGAAGAACAGGATAAAGCTCGCCGGGAATGGGAAAGACAGAAGAGAAGGGAAATGGCAAGGGAGCATTCCAGGAGAGAAAGGGACCGCTTGGAGCAGTT
AGAAAGGAAGCGGGAGCGGGAGCGCAAGATGCGGGAGCAGCAGAAGGAGCAGCGGGAGCAGAAGGAGCGCGAGCGGCGGGCGGAGGAGCGGCGCAAGGAG
CGGGAGGCCCGCAGGGAAGTGTCTGCACATCACCGAACGATGAGAGAGGACTACAGCGACAAAGTGAAAGCCAGCCACTGGAGTCGCAGCCCGCCTCGGC
CGCCGCGGGAGCGGTTCGAGTTGGGAGACGGCCGGAAGCCAGGTGAGGCCAGGCCGGCGCCTGCGCAGAAGCCAGCACAGTTAAAAGAAGAGAAAATGGA
AGAAAGGGACCTGCTGTCCGACTTACAGGACATCAGCGACAGCGAGAGGAAGACCAGCTCGGCCGAGTCCTCGTCAGCGGAATCAGGCTCAGGTTCTGAG
GAAGAAGAGGAGGAGGAGGAAGAGGAGGAGGAGGAAGGGAGCACCAGTGAAGAATCAGAGGAGGAGGAGGAGGAAGAGGAAGAGGAGGAGGAGGAGACCG
GCAGCAACTCTGAGGAGGCATCAGAGCAGTCTGCCGAAGAAGTAAGTGAGGAAGAAATGAGTGAAGATGAAGAACGAGAAAATGAAAACCACCTCTTGGT
TGTTCCAGAGTCACGGTTCGACCGAGATTCCGGGGAGAGTGAAGAAGCAGAGGAAGAAGTGGGGCTGCCGGAGCGTCGAGGAGTTCCAGTGCCTGAACAG
GATCGAGGAGGGCACCTATGGAGTGGTCTACAGAGCAAAAGACAAGAAAACAGATGAAATTGTGGCTCTAAAGCGGCTGAAGATGGAGAAGGAGAAGGAG
GGCTTCCCGATCACGTCCCTGAGGGAGATCAACACCATCCTCAAGGCCCAGCATCCCAACATTGTCACCGTTAGAGAGATTGTGGTGGGCAGCAACATGG
ACAAGATCTACATCGTGATGAACTACGTGGAGCACGACCTCAAGAGCCTGATGGAGACCATGAAACAGCCCTTCCTGCCAGGGGAGGTGAAGACCCTGAT
GATCCAGCTGCTGCGGGGGGTGAAACACCTGCACGACAACTGGATCCTGCACCGTGACCTCAAGACGTCCAACCTGCTGCTGAGCCACGCCGGCATCCTC
AAGGTGGGTGATTTTGGGCTGGCGCGGGAGTACGGATCCCCTCTGAAGGCCTACACCCCGGTCGTGGTGACCCAGTGGTACCGCGCCCCAGAGCTGCTGC
TTGGTGCCAAGGAATACTCCACGGCCGTGGACATGTGGTCAGTGGGCTGCATCTTCGGGGAGCTGCTGACTCAGAAGCCTCTGTTCCCCGGGAATTCGGA
AATCGATCAGATCAACAAAGTGTTCAAGGAGCTGGGGACCCCCAGTGAGAAAATCTGGCCCGGCTACAGTGAGCTCCCAGTAGTCAAAAAGATGACCTTC
AGCGAGCACCCCTACAACAACCTCCGCAAGCGCTTCGGGGCTCTGCTCTCAGACCAGGGCTTCGACCTCATGAACAAGTTCCTGACCTACTTCCCCGGGA
GGAGGATCAGCGCTGAGGACGGCCTCAAGCATGAGTATTTCCGCGAGACCCCCCTCCCCATCGACCCCTCCATGTTCCCCACGTGGCCCGCCAAGAGCGA
GCAGCAGCGTGTGAAGCGGGGCACCAGCCCGAGGCCCCCTGAGGGAGGCCTGGGCTACAGCCAGCTGGGTGACGACGACCTGAAGGAGACGGGCTTCCAC
CTTACCACCACGAACCAGGGGGCCTCTGCCGCGGGCCCCGGCTTCAGCCTCAAGTTCTGAAGGTCAGAGTGGACCCCGTCATGGGG
  • CDC2L1.u.f.9 (forward primer)
  • refseq_CDC2L1.R1 (reverse primer)
  • Single exon skipping

Frame 0

TQEVRILLASAGCCFFSGSGTGRGPVGCFNSNG
**KGLLESENFR*NSSGKETKEGTRGESRDKTLK
KF**PGFQAGFP*GGGAERSLHGDHNKELPV*K
RRLNGRQRRRR*FFGHQTTPANVSERKSSSQKR
*KEKRKM*AS*PFSRRGEAC*SERKRARTSETTS
RRTG*SSPGMGKTEEKGNGKGAFQERKGPLGAV
RKEAGAGAQDAGAAEGAAGAEGARAAGGGAAQG
AGGPQGSVCTSPNDERGLQRQSESQPLESQPASA
AAGAVRVGRRPEAR*GQAGACAEASTVKRRENG
RKGPAVRLTGHQRQREEDQLGRVLVSGIRLRF*
GRRGGGGRGGGGREHQ*RIRGGGGGRGRGGGGDR
QQL*GGIRAVCRRSK*GRNE*R*RTRK*KPPLG
CSRVTVRPRFRGE*RSRGRSGAAGASRSSSA*T
GSRRAPMEWSTEQKTRKQMKLWL*SG*RWRRRRR
ASRSRP*GRSTPSSRPSIPTLSPLERLWWAATW
TRSTS**TTWSTTSRA*WRP*NSPSCQGR*RP*
*SSCCGG*NTCTTTGSCTVTSRRPTCC*ATPASS
RWVILGWRGSTDPL*RPTPRSW*PSGTAPQSCC
LVPRNTPRPWTCGQWAASSGSC*LRSLCSPGIR
KSIRSTKCSRSWGPPVRKSGPATVSSQ*SKR*PS
ASTPTTTSASASGLCSQTRASTS*TSS*PTSPG
GGSALRTASSMSISARPPSPSTPPCSPRGPPRA
SSSV*SGAPARGPLREAWATASWVTTT*RRRAST
LPPRTRGPLPRAPASASSSEGQSGPRHG

Frame 1

HRK*GYFWRAPVAVSSQAQGPAAAP*GVLTQMG
DEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRL
KNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRR
EDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKD
EKRKEKCRHHSHSAEGGKHARVKEREHERRKRH
REEQDKARREWERQKRREMAREHSRRERDRLEQL
ERKRERERKMREQQKEQREQKERERRAEERRKE
REARREVSAHHRTMREDYSDKVKASHWSRSPPR
PPRERFELGDGRKPGEARPAPAQKPAQLKEEKME
ERDLLSDLQDISDSERKTSSAESSSAESGSGSE
EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEET
GSNSEEASEQSAEEVSEEEMSEDEERENENHLLV
VPESRFDRDSGESEEAEEEVGLPERRGVPVPEQ
DRGGHLWSGLQSKRQENR*NCGSKAAEDGEGEG
GLPDHVPEGDQHHPQGPASQHCHR*RDCGGQQHG
QDLHRDELRGARPQEPDGDHETALPARGGEDPD
DPAAAGGETPARQLDPAP*PQDVQPAAEPRRHP
QGG*FWAGAGVRIPSEGLHPGRGDPVVPRPRAAA
WCQGILHGRGHVVSGLHLRGAADSEASVPREFG
NRSDQQSVQGAGDPQ*ENLARLQ*APSSQKDDL
QRAPLQQPPQALRGSALRPGLRPHEQVPDLLPRE
EDQR*GRPQA*VFPRDPPPHRPLHVPHVARQER
AAACEAGHQPEAP*GRPGLQPAG*RRPEGDGLP
PYHHEPGGLCRGPRLQPQVLKVRVDPVMG

Frame 2

TGSEDTSGERRLLFLLRLRDRPRPRRVF*LKWV
MKRTLGK*KL*MKFFRKRNEGRNKRRKQR*NA*
KILMTGIPSGIPLRRGS*EITAWRSQ*GTPRIE
EKTQWKTEEKKMILWPSNHPSKCLGKKKFITEKM
KREKKNVGIIAIQQKGGSMLE*KKESTNVGNDI
EKNRIKLAGNGKDRREGKWQGSIPGEKGTAWSS
*KGSGSGSARCGSSRRSSGSRRSASGGRRSGARS
GRPAGKCLHITER*ERTTATK*KPATGVAARLG
RRGSGSSWETAGSQVRPGRRLRRSQHS*KKRKW
KKGTCCPTYRTSATARGRPARPSPRQRNQAQVLR
KKRRRRKRRRRKGAPVKNQRRRRRKRKRRRRRP
AATLRRHQSSLPKK*VRKK*VKMKNEKMKTTSW
LFQSHGSTEIPGRVKKQRKKWGCRSVEEFQCLNR
IEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKE
GFPITSLREINTILKAQHPNIVTVREIVVGSNM
DKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLM
IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGIL
KVGDFGLAREYGSPLKAYTPVVVTQWYRAPELL
LGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSE
IDQINKVFKELGTPSEKIWPGYSELPVVKKMTF
SEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPG
RRISAEDGLKHEYFRETPLPIDPSMFPTWPAKSE
QQRVKRGTSPRPPEGGLGYSQLGDDDLKETGFH
LTTTNQGASAAGPGFSLKF*RSEWTPSW

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