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Sequences

Sequence NM_182480

CTTTCCCGGGGGCAGTCTCTTTTCTCTCCTCACCTGACGGCTCCCCTCCGCGCCTCCGGGGGCTCCCTCAGGCCTCCCCACGGTCATTTCAGCTGGACAG
AGGCAGCAGCGACAGTGACAGCGATAGTGGCAGCAGCGGTGGCAGCGAGAGCTATGCGGGGCCAGGGTCCACCCCTTTCTAGCTTTGGCGTCTGGTTGGC
TTCCAGGGCAGCCTCCGATCCATCCCGCCCGAGGAGGCAAGGATATGATATTCACTTTCATGACAAGAAAATCCTGTTGCTCGAAGCAGGTCCAAAGAAA
GTACTGGAGAAATTGTCAGAAACTTACAGCAACAGGGTCAGCTCCATTTCCCCTGGCTCTGCAACGCTTCTCAGTAGTGTGGGACGCCTGCTCAGAGGCC
CTGATAATGTTTGATAAGGATAATTTAGATGACATGGGCTATATCGTGGAGAATGATGTCATCATGCATGCTCTCACTAAGCAGTTGGAGGCTGTGTCTG
ACCGAGTGACGGTTCTCTACAGGAGCAAAGCCATTCGCTATACCTGGCCTTGTCCATTTCCTATGGCCGACTCCAGCCCTTGGGTTCATATTACCCTAGG
TGATGGCAGCACCTTCCAGACCAAATTGTTGATAGGTGCAGATGGTCACAACTCCGGAGTACGGCAGGCTGTTGGAATCCAGAATGTGAGCTGGAACTAT
GACCAGTCTGCTGTTGTGGCTACTCTGCATTTATCAGAGGCCACAGAAAACAACGTAGCCTGGCAGAGATTTCTTCCCTCTGGGCCTATTGCTCTGCTCC
CGCTCTCAGACACCTTGAGTTCCTTGGTTTGGTCCACGTCCCATGAACATGCAGCAGAGCTAGTTAGCATGGATGAGGAAAAATTTGTGGATGCCGTTAA
CTCTGCCTTTTGGAGTGATGCTGACCACACGGACTTCATCGACACAGCTGGTGCCATGCTGCAGTATGCTGTCAGCCTTCTGAAGCCCACTAAGGTCTCG
GCTCGCCAGCTGCCCCCAAGCGTAGCCAGGGTGGATGCCAAAAGCCGAGTTCTGTTTCCTCTTGGGTTGGGACATGCTGCTGAGTACGTCAGGCCTCGGG
TGGCGCTCATTGGGGATGCAGCCCACAGAGTCCATCCGCTTGCAGGACAGGGTGTCAACATGGGCTTTGGGGATATCTCCAGCTTGGCCCATCACCTCAG
TACGGCAGCCTTCAATGGGAAGGACTTAGGTTCCGTGAGCCACCTCACAGGTTATGAAACAGAAAGACAGCGTCACAACACTGCTCTTCTGGCTGCTACA
GACTTACTAAAAAGGCTCTATTCTACCAGTGCCTCCCCGCTTGTGTTGCTCAGGACGTGGGGCTTGCAGGCCACAAATGCAGTGTCTCCACTCAAAGAAC
AGATTATGGCCTTTGCAAGCAAATGAGTACTCCTCTCCTAAAGAAAGATTACGTTGATGAAAAAGAACATCCTGCCCAGGACCCATCATACATATTTTCA
AGATCTTATTTAATTTAATAAACTTACTTTACATTAAAA
  • refseq_COQ6.F1 (forward primer)
  • refseq_COQ6.R1 (reverse primer)
  • Single exon skipping

Frame 0

LSRGQSLFSPHLTAPLRASGGSLRPPHGHFSWT
EAAATVTAIVAAAVAARAMRGQGPPLSSFGVWLA
SRAASDPSRPRRQGYDIHFHDKKILLLEAGPKK
VLEKLSETYSNRVSSISPGSATLLSSVGRLLRG
PDNV**G*FR*HGLYRGE*CHHACSH*AVGGCV*
PSDGSLQEQSHSLYLALSISYGRLQPLGSYYPR
*WQHLPDQIVDRCRWSQLRSTAGCWNPECELEL
*PVCCCGYSAFIRGHRKQRSLAEISSLWAYCSAP
ALRHLEFLGLVHVP*TCSRAS*HG*GKICGCR*
LCLLE*C*PHGLHRHSWCHAAVCCQPSEAH*GL
GSPAAPKRSQGGCQKPSSVSSWVGTCC*VRQASG
GAHWGCSPQSPSACRTGCQHGLWGYLQLGPSPQ
YGSLQWEGLRFREPPHRL*NRKTASQHCSSGCY
RLTKKALFYQCLPACVAQDVGLAGHKCSVSTQRT
DYGLCKQMSTPLLKKDYVDEKEHPAQDPSYIFS
RSYLI**TYFTLK

Frame 1

FPGGSLFSLLT*RLPSAPPGAPSGLPTVISAGQ
RQQRQ*QR*WQQRWQRELCGARVHPFLALASGW
LPGQPPIHPARGGKDMIFTFMTRKSCCSKQVQRK
YWRNCQKLTATGSAPFPLALQRFSVVWDACSEA
LIMFDKDNLDDMGYIVENDVIMHALTKQLEAVS
DRVTVLYRSKAIRYTWPCPFPMADSSPWVHITLG
DGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNY
DQSAVVATLHLSEATENNVAWQRFLPSGPIALL
PLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVN
SAFWSDADHTDFIDTAGAMLQYAVSLLKPTKVS
ARQLPPSVARVDAKSRVLFPLGLGHAAEYVRPR
VALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLS
TAAFNGKDLGSVSHLTGYETERQRHNTALLAAT
DLLKRLYSTSASPLVLLRTWGLQATNAVSPLKE
QIMAFASK*VLLS*RKITLMKKNILPRTHHTYFQ
DLI*FNKLTLH*

Frame 2

FPGAVSFLSSPDGSPPRLRGLPQASPRSFQLDR
GSSDSDSDSGSSGGSESYAGPGSTPF*LWRLVG
FQGSLRSIPPEEARI*YSLS*QENPVARSRSKE
STGEIVRNLQQQGQLHFPWLCNASQ*CGTPAQRP
**CLIRII*MTWAISWRMMSSCMLSLSSWRLCL
TE*RFSTGAKPFAIPGLVHFLWPTPALGFILP*
VMAAPSRPNC**VQMVTTPEYGRLLESRM*AGTM
TSLLLWLLCIYQRPQKTT*PGRDFFPLGLLLCS
RSQTP*VPWFGPRPMNMQQS*LAWMRKNLWMPL
TLPFGVMLTTRTSSTQLVPCCSMLSAF*SPLRSR
LASCPQA*PGWMPKAEFCFLLGWDMLLSTSGLG
WRSLGMQPTESIRLQDRVSTWALGISPAWPITS
VRQPSMGRT*VP*ATSQVMKQKDSVTTLLFWLLQ
TY*KGSILPVPPRLCCSGRGACRPQMQCLHSKN
RLWPLQANEYSSPKERLR**KRTSCPGPIIHIF
KILFNLINLLYIK

Sequence NM_182476

GGGATTGGAGTGCTCTGCTCCGGACGCACTACGTAGGTGGGCCTGCGGGAGTTCTGAGTGCGACGGCGCAGGTCTGCACCATGGCGGCCCGGCTTGTCAG
CCGATGCGGGGCTGTGCGTGCAGCTCCCCACAGCGGCCCGCTGGTGTCCTGGCGCAGGTGGTCCGGCGCCTCAACAGACACCGTGTATGACGTGGTGGTG
TCGGGTGGAGGCCTGGTGGGCGCTGCCATGGCCTGTGCCTTGGGATATGATATTCACTTTCATGACAAGAAAATCCTGTTGCTCGAAGCAGGTCCAAAGA
AAGTACTGGAGAAATTGTCAGAAACTTACAGCAACAGGGTCAGCTCCATTTCCCCTGGCTCTGCAACGCTTCTCAGTAGTTTTGGTGCCTGGGACCATAT
CTGCAACATGAGATACAGAGCCTTTCGGCGAATGCAGGTGTGGGACGCCTGCTCAGAGGCCCTGATAATGTTTGATAAGGATAATTTAGATGACATGGGC
TATATCGTGGAGAATGATGTCATCATGCATGCTCTCACTAAGCAGTTGGAGGCTGTGTCTGACCGAGTGACGGTTCTCTACAGGAGCAAAGCCATTCGCT
ATACCTGGCCTTGTCCATTTCCTATGGCCGACTCCAGCCCTTGGGTTCATATTACCCTAGGTGATGGCAGCACCTTCCAGACCAAATTGTTGATAGGTGC
AGATGGTCACAACTCCGGAGTACGGCAGGCTGTTGGAATCCAGAATGTGAGCTGGAACTATGACCAGTCTGCTGTTGTGGCTACTCTGCATTTATCAGAG
GCCACAGAAAACAACGTAGCCTGGCAGAGATTTCTTCCCTCTGGGCCTATTGCTCTGCTCCCGCTCTCAGACACCTTGAGTTCCTTGGTTTGGTCCACGT
CCCATGAACATGCAGCAGAGCTAGTTAGCATGGATGAGGAAAAATTTGTGGATGCCGTTAACTCTGCCTTTTGGAGTGATGCTGACCACACGGACTTCAT
CGACACAGCTGGTGCCATGCTGCAGTATGCTGTCAGCCTTCTGAAGCCCACTAAGGTCTCGGCTCGCCAGCTGCCCCCAAGCGTAGCCAGGGTGGATGCC
AAAAGCCGAGTTCTGTTTCCTCTTGGGTTGGGACATGCTGCTGAGTACGTCAGGCCTCGGGTGGCGCTCATTGGGGATGCAGCCCACAGAGTCCATCCGC
TTGCAGGACAGGGTGTCAACATGGGCTTTGGGGATATCTCCAGCTTGGCCCATCACCTCAGTACGGCAGCCTTCAATGGGAAGGACTTAGGTTCCGTGAG
CCACCTCACAGGTTATGAAACAGAAAGACAGCGTCACAACACTGCTCTTCTGGCTGCTACAGACTTACTAAAAAGGCTCTATTCTACCAGTGCCTCCCCG
CTTGTGTTGCTCAGGACGTGGGGCTTGCAGGCCACAAATGCAGTGTCTCCACTCAAAGAACAGATTATGGCCTTTGCAAGCAAATGAGTACTCCTCTCCT
AAAGAAAGATTACGTTGATGAAAAAGAACATCCTGCCCAGGACCCATCATACATATTTTCAAGATCTTATTTAATTTAATAAACTTACTTTACATTAAAA
  • refseq_COQ6.F1 (forward primer)
  • refseq_COQ6.R1 (reverse primer)
  • Single exon skipping

Frame 0

GIGVLCSGRTT*VGLREF*VRRRRSAPWRPGLS
ADAGLCVQLPTAARWCPGAGGPAPQQTPCMTWWC
RVEAWWALPWPVPWDMIFTFMTRKSCCSKQVQR
KYWRNCQKLTATGSAPFPLALQRFSVVLVPGTI
SAT*DTEPFGECRCGTPAQRP**CLIRII*MTWA
ISWRMMSSCMLSLSSWRLCLTE*RFSTGAKPFA
IPGLVHFLWPTPALGFILP*VMAAPSRPNC**V
QMVTTPEYGRLLESRM*AGTMTSLLLWLLCIYQR
PQKTT*PGRDFFPLGLLLCSRSQTP*VPWFGPR
PMNMQQS*LAWMRKNLWMPLTLPFGVMLTTRTS
STQLVPCCSMLSAF*SPLRSRLASCPQA*PGWMP
KAEFCFLLGWDMLLSTSGLGWRSLGMQPTESIR
LQDRVSTWALGISPAWPITSVRQPSMGRT*VP*
ATSQVMKQKDSVTTLLFWLLQTY*KGSILPVPPR
LCCSGRGACRPQMQCLHSKNRLWPLQANEYSSP
KERLR**KRTSCPGPIIHIFKILFNLINLLYIK

Frame 1

GLECSAPDALRRWACGSSECDGAGLHHGGPACQ
PMRGCACSSPQRPAGVLAQVVRRLNRHRV*RGG
VGWRPGGRCHGLCLGI*YSLS*QENPVARSRSKE
STGEIVRNLQQQGQLHFPWLCNASQ*FWCLGPY
LQHEIQSLSANAGVGRLLRGPDNV**G*FR*HG
LYRGE*CHHACSH*AVGGCV*PSDGSLQEQSHSL
YLALSISYGRLQPLGSYYPR*WQHLPDQIVDRC
RWSQLRSTAGCWNPECELEL*PVCCCGYSAFIR
GHRKQRSLAEISSLWAYCSAPALRHLEFLGLVHV
P*TCSRAS*HG*GKICGCR*LCLLE*C*PHGLH
RHSWCHAAVCCQPSEAH*GLGSPAAPKRSQGGC
QKPSSVSSWVGTCC*VRQASGGAHWGCSPQSPSA
CRTGCQHGLWGYLQLGPSPQYGSLQWEGLRFRE
PPHRL*NRKTASQHCSSGCYRLTKKALFYQCLP
ACVAQDVGLAGHKCSVSTQRTDYGLCKQMSTPLL
KKDYVDEKEHPAQDPSYIFSRSYLI**TYFTLK

Frame 2

DWSALLRTHYVGGPAGVLSATAQVCTMAARLVS
RCGAVRAAPHSGPLVSWRRWSGASTDTVYDVVV
SGGGLVGAAMACALGYDIHFHDKKILLLEAGPK
KVLEKLSETYSNRVSSISPGSATLLSSFGAWDHI
CNMRYRAFRRMQVWDACSEALIMFDKDNLDDMG
YIVENDVIMHALTKQLEAVSDRVTVLYRSKAIR
YTWPCPFPMADSSPWVHITLGDGSTFQTKLLIGA
DGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSE
ATENNVAWQRFLPSGPIALLPLSDTLSSLVWST
SHEHAAELVSMDEEKFVDAVNSAFWSDADHTDFI
DTAGAMLQYAVSLLKPTKVSARQLPPSVARVDA
KSRVLFPLGLGHAAEYVRPRVALIGDAAHRVHP
LAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVS
HLTGYETERQRHNTALLAATDLLKRLYSTSASP
LVLLRTWGLQATNAVSPLKEQIMAFASK*VLLS
*RKITLMKKNILPRTHHTYFQDLI*FNKLTLH*

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