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Sequences

Sequence NM_021872

GCAGCCAGTCGCGGAGGCGGGGAGGCTGCGCGGTCAGAGGCGCCTGGAGCGAGCGAATCCTGGCCCACCGCCTGCCCAACCGCGTGACCTTGATTGAGTT AATGAACTTCACGCCTCAGCGTCCAGGTCTGTAAAATGGGGTGTCTAACGCAGACCGTACAGCCCAGCTGGGTTTAGCAAACTTCCGGGAGCCAGTTGGA GCCTCTCCCCATCCCTAGCGGTGATCCCAGGTGACGACATGCCGCGGGGGGTCCTGCGGAGGCCACCCTAGGGCGTTGCTGCTGCCTTTGGGAGTGTGGA GCTCCAAACCATGTCGCGAGAGGCGGATTTTGGGAGGCCGGGATCCTCGCGCCAGGGGGATGTGCGAGGGTGTGGGATAAATCTTAATTCCTCCGGCCCA CCCAAAGCCTGGAAATCCAGCCTCCGCGCCTCTTGCCCTGCGGGCCCCGCCCTCAGTCCCGCCCTCATCTAACCCGCTACCCCATTGGTGGCGTCCGGCG GCGCGGCTGCTGTTATTTTTCGAATATATAAGGAGGTGGAAGTGGCAGCTGCAACTAGAGGCTTCCCTGGCTGGTGCCTGAGCCCGGCGTCCCTCGCCCC CCGCCCTCCCCGCATCCCTCTCCTCCCTCGCGCCTGGCCCTGTGGCTCTTCCTCCCTCCCTCCTTCCCCCCCCCCCCACCCCTCGCCCGCTGCCTCCCTC GGCCCAGCCAGCTGTGCCGGCGTTTGTTGGCTGCCCTGCGCCCGGCCCTCCAGCCAGCCTTCTGCCGGCCCCGCCGCGATGGAGGTGCCCCAGCCGGAGC CCGCGCCAGGCTCGGCTCTCAGTCCAGCAGGCGTGTGCGGTGGCGCCCAGCGTCCGGGCCACCTCCCGGGCCTCCTGCTGGGATCTCATGGCCTCCTGGG GTCCCCGGTGCGGGCGGCCGCTTCCTCGCCGGTCACCACCCTCACCCAGACCATGCACGACCTCGCCGGGCTCGGCAGCGAAACCCCAAAGAGTCAGGTA GGGACCCTGCTCTTCCGCAGCCGCAGCCGCCTGACGCACCTATCCCTGTCTCGACGGGCATCCGAATCCTCCCTGTCGTCTGAATCCTCCGAATCTTCTG ATGCAGGTCTCTGCATGGATTCCCCCAGCCCTATGGACCCCCACATGGCGGAGCAGACGTTTGAACAGGCCATCCAGGCAGCCAGCCGGATCATTCGAAA CGAGCAGTTTGCCATCAGACGCTTCCAGTCTATGCCGGATGGATTTGTCTTCAAGATGCCATGGAAGCCCACACATCCCAGCTCCACCCATGCTCTGGCA GAGTGGGCCAGCCGCAGGGAAGCCTTTGCCCAGAGACCCAGCTCGGCCCCCGACCTGATGTGTCTCAGTCCTGACCGGAAGATGGAAGTGGAGGAGCTCA GCCCCCTGGCCCTAGGTCGCTTCTCTCTGACCCCTGCAGAGGGGGATACTGAGGAAGATGATGGATTTGTGGACATCCTAGAGAGTGACTTAAAGGATGA TGATGCAGTTCCCCCAGGCATGGAGAGTCTCATTAGTGCCCCACTGGTCAAGACCTTGGAAAAGGAAGAGGAAAAGGACCTCGTCATGTACAGCAAGTGC CAGCGGCTCTTCCGCTCTCCGTCCATGCCCTGCAGCGTGATCCGGCCCATCCTCAAGAGGCTGGAGCGGCCCCAGGACAGGGACACGCCCGTGCAGAATA AGCGGAGGCGGAGCGTGACCCCTCCTGAGGAGCAGCAGGAGGCTGAGGAACCTAAAGCCCGCGTCCTCCGCTCAAAATCACTGTGTCACGATGAGATCGA GAACCTCCTGGACAGTGACCACCGAGAGCTGATTGGAGATTACTCTAAGGCCTTCCTCCTACAGACAGTAGACGGAAAGCACCAAGACCTCAAGTACATC TCACCAGAAACGATGGTGGCCCTATTGACGGGCAAGTTCAGCAACATCGTGGATAAGTTTGTGATTGTAGACTGCAGATACCCCTATGAATATGAAGGCG GGCACATCAAGACTGCGGTGAACTTGCCCCTGGAACGCGACGCCGAGAGCTTCCTACTGAAGAGCCCCATCGCGCCCTGTAGCCTGGACAAGAGAGTCAT CCTCATTTTCCACTGTGAATTCTCATCTGAGCGTGGGCCCCGCATGTGCCGTTTCATCAGGGAACGAGACCGTGCTGTCAACGACTACCCCAGCCTCTAC TACCCTGAGATGTATATCCTGAAAGGCGGCTACAAGGAGTTCTTCCCTCAGCACCCGAACTTCTGTGAACCCCAGGACTACCGGCCCATGAACCACGAGG CCTTCAAGGATGAGCTAAAGACCTTCCGCCTCAAGACTCGCAGCTGGGCTGGGGAGCGGAGCCGGCGGGAGCTCTGTAGCCGGCTGCAGGACCAGTGAGG GGCCTGCGCCAGTCCTGCTACCTCCCTTGCCTTTCGAGGCCTGAAGCCAGCTGCCCTATGGGCCTGCCGGGCTGAGGGCCTGCTGGAGGCCTCAGGTGCT GTCCATGGGAAAGATGGTGTGGGTGTCCTGCCTGTCTGCCCCAGCCCAGATTCCCCTGTGTCATCCCATCATTTTCCATATCCTGGTGCCCCCCACCCCT GGAAGAGCCCAGTCTGTTGAGTTAGTTAAGTTGGGTTAATACCAGCTTAAAGGCAGTATTTTGTGTCCTCCAGGAGCTTCTTGTTTCCTTGTTAGGGTTA ACCCTTCATCTTCCTGTGTCCTGAAACGCTCCTTTGTGTGTGTGTCAGCTGAGGCTGGGGGAGAGCCGTGGTCCCTGAGGATGGGTCAGAGCTAAACTCC TTCCTGGCCTGAGAGTCAGCTCTCTGCCCTGTGTACTTCCCGGGCCAGGGCTGCCCCTAATCTCTGTAGGAACCGTGGTATGTCTGCCATGTTGCCCCTT TCTCTTTTCCCCTTTCCTGTCCCACCATACGAGCACCTCCAGCCTGAACAGAAGCTCTTACTCTTTCCTATTTCAGTGTTACCTGTGTGCTTGGTCTGTT TGACTTTACGCCCATCTCAGGACACTTCCGTAGACTGTTTAGGTTCCCCTGTCAAATATCAGTTACCCACTCGGTCCCAGTTTTGTTGCCCCAGAAAGGG ATGTTATTATCCTTGGGGGCTCCCAGGGCAAGGGTTAAGGCCTGAATCATGAGCCTGCTGGAAGCCCAGCCCCTACTGCTGTGAACCCTGGGGCCTGACT GCTCAGAACTTGCTGCTGTCTTGTTGCGGATGGATGGAAGGTTGGATGGATGGGTGGATGGCCGTGGATGGCCGTGGATGCGCAGTGCCTTGCATACCCA AACCAGGTGGGAGCGTTTTGTTGAGCATGACAGCCTGCAGCAGGAATATATGTGTGCCTATTTGTGTGGACAAAAATATTTACACTTAGGGTTTGGAGCT ATTCAAGAGGAAATGTCACAGAAGCAGCTAAACCAAGGACTGAGCACCCTCTGGATTCTGAATCTCAAGATGGGGGCAGGGCTGTGCTTGAAGGCCCTGC TGAGTCATCTGTTAGGGCCTTGGTTCAATAAAGCACTGAGCAAGTTGAGAAA

refseq_CDC25B.F3 (forward primer)
refseq_CDC25B.R3 (reverse primer)
Single exon skipping

Frame 0

AASRGGGEAARSEAPGASESWPTACPTA*P*LS **TSRLSVQVCKMGCLTQTVQPSWV*QTSGSQLE PLPIPSGDPR*RHAAGGPAEATLGRCCCLWECG APNHVARGGFWEAGILAPGGCARVWDKS*FLRP TQSLEIQPPRLLPCGPRPQSRPHLTRYPIGGVRR RGCCYFSNI*GGGSGSCN*RLPWLVPEPGVPRP PPSPHPSPPSRLALWLFLPPSFPPPPPLARCLP RPSQLCRRLLAALRPALQPAFCRPRRDGGAPAGA RARLGSQSSRRVRWRPASGPPPGPPAGISWPPG VPGAGGRFLAGHHPHPDHARPRRARQRNPKESG RDPALPQPQPPDAPIPVSTGIRILPVV*ILRIF* CRSLHGFPQPYGPPHGGADV*TGHPGSQPDHSK RAVCHQTLPVYAGWICLQDAMEAHTSQLHPCSG RVGQPQGSLCPETQLGPRPDVSQS*PEDGSGGAQ PPGPRSLLSDPCRGGY*GR*WICGHPRE*LKG* *CSSPRHGESH*CPTGQDLGKGRGKGPRHVQQV PAALPLSVHALQRDPAHPQEAGAAPGQGHARAE* AEAERDPS*GAAGG*GT*SPRPPLKITVSR*DR EPPGQ*PPRADWRLL*GLPPTDSRRKAPRPQVH LTRNDGGPIDGQVQQHRG*VCDCRLQIPL*I*RR AHQDCGELAPGTRRRELPTEEPHRAL*PGQESH PHFPL*ILI*AWAPHVPFHQGTRPCCQRLPQPL LP*DVYPERRLQGVLPSAPELL*TPGLPAHEPRG LQG*AKDLPPQDSQLGWGAEPAGAL*PAAGPVR GLRQSCYLPCLSRPEASCPMGLPG*GPAGGLRC CPWERWCGCPACLPQPRFPCVIPSFSISWCPPPL EEPSLLS*LSWVNTSLKAVFCVLQELLVSLLGL TLHLPVS*NAPLCVCQLRLGESRGP*GWVRAKL LPGLRVSSLPCVLPGPGLPLISVGTVVCLPCCPF LFSPFLSHHTSTSSLNRSSYSFLFQCYLCAWSV *LYAHLRTLP*TV*VPLSNISYPLGPSFVAPER DVIILGGSQGKG*GLNHEPAGSPAPTAVNPGA*L LRTCCCLVADGWKVGWMGGWPWMAVDAQCLAYP NQVGAFC*A*QPAAGIYVCLFVWTKIFTLRVWS YSRGNVTEAAKPRTEHPLDSESQDGGRAVLEGPA ESSVRALVQ*STEQVEK

Frame 1

QPVAEAGRLRGQRRLERANPGPPPAQPRDLD*V NELHASASRSVKWGV*RRPYSPAGFSKLPGASW SLSPSLAVIPGDDMPRGVLRRPP*GVAAAFGSVE LQTMSREADFGRPGSSRQGDVRGCGINLNSSGP PKAWKSSLRASCPAGPALSPALI*PATPLVASG GAAAVIFRIYKEVEVAAATRGFPGWCLSPASLAP RPPRIPLLPRAWPCGSSSLPPSPPPHPSPAASL GPASCAGVCWLPCARPSSQPSAGPAAMEVPQPE PAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLG SPVRAAASSPVTTLTQTMHDLAGLGSETPKSQV GTLLFRSRSRLTHLSLSRRASESSLSSESSESS DAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRN EQFAIRRFQSMPDGFVFKMPWKPTHPSSTHALA EWASRREAFAQRPSSAPDLMCLSPDRKMEVEEL SPLALGRFSLTPAEGDTEEDDGFVDILESDLKDD DAVPPGMESLISAPLVKTLEKEEEKDLVMYSKC QRLFRSPSMPCSVIRPILKRLERPQDRDTPVQN KRRRSVTPPEEQQEAEEPKARVLRSKSLCHDEIE NLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYI SPETMVALLTGKFSNIVDKFVIVDCRYPYEYEG GHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVI LIFHCEFSSERGPRMCRFIRERDRAVNDYPSLY YPEMYILKGGYKEFFPQHPNFCEPQDYRPMNHE AFKDELKTFRLKTRSWAGERSRRELCSRLQDQ*G ACASPATSLAFRGLKPAALWACRAEGLLEASGA VHGKDGVGVLPVCPSPDSPVSSHHFPYPGAPHP WKSPVC*VS*VGLIPA*RQYFVSSRSFLFPC*G* PFIFLCPETLLCVCVS*GWGRAVVPEDGSELNS FLA*ESALCPVYFPGQGCP*SL*EPWYVCHVAP FSFPLSCPTIRAPPA*TEALTLSYFSVTCVLGLF DFTPISGHFRRLFRFPCQISVTHSVPVLLPQKG MLLSLGAPRARVKA*IMSLLEAQPLLL*TLGPD CSELAAVLLRMDGRLDGWVDGRGWPWMRSALHTQ TRWERFVEHDSLQQEYMCAYLCGQKYLHLGFGA IQEEMSQKQLNQGLSTLWILNLKMGAGLCLKAL LSHLLGPWFNKALSKLR

Frame 2

SQSRRRGGCAVRGAWSERILAHRLPNRVTLIEL MNFTPQRPGL*NGVSNADRTAQLGLANFREPVG ASPHP*R*SQVTTCRGGSCGGHPRALLLPLGVW SSKPCRERRILGGRDPRARGMCEGVG*ILIPPAH PKPGNPASAPLALRAPPSVPPSSNPLPHWWRPA ARLLLFFEYIRRWKWQLQLEASLAGA*ARRPSP PALPASLSSLAPGPVALPPSLLPPPPTPRPLPPS AQPAVPAFVGCPAPGPPASLLPAPPRWRCPSRS PRQARLSVQQACAVAPSVRATSRASCWDLMASW GPRCGRPLPRRSPPSPRPCTTSPGSAAKPQRVR* GPCSSAAAAA*RTYPCLDGHPNPPCRLNPPNLL MQVSAWIPPALWTPTWRSRRLNRPSRQPAGSFE TSSLPSDASSLCRMDLSSRCHGSPHIPAPPMLWQ SGPAAGKPLPRDPARPPT*CVSVLTGRWKWRSS APWP*VASL*PLQRGILRKMMDLWTS*RVT*RM MMQFPQAWRVSLVPHWSRPWKRKRKRTSSCTASA SGSSALRPCPAA*SGPSSRGWSGPRTGTRPCRI SGGGA*PLLRSSRRLRNLKPASSAQNHCVTMRS RTSWTVTTES*LEITLRPSSYRQ*TESTKTSSTS HQKRWWPY*RASSATSWISL*L*TADTPMNMKA GTSRLR*TCPWNATPRASY*RAPSRPVAWTRES SSFSTVNSHLSVGPACAVSSGNETVLSTTTPAST TLRCIS*KAATRSSSLSTRTSVNPRTTGP*TTR PSRMS*RPSASRLAAGLGSGAGGSSVAGCRTSE GPAPVLLPPLPFEA*SQLPYGPAGLRACWRPQVL SMGKMVWVSCLSAPAQIPLCHPIIFHILVPPTP GRAQSVELVKLG*YQLKGSILCPPGASCFLVRV NPSSSCVLKRSFVCVSAEAGGEPWSLRMGQS*TP SWPESQLSALCTSRARAAPNLCRNRGMSAMLPL SLFPFPVPPYEHLQPEQKLLLFPISVLPVCLVC LTLRPSQDTSVDCLGSPVKYQLPTRSQFCCPRKG CYYPWGLPGQGLRPES*ACWKPSPYCCEPWGLT AQNLLLSCCGWMEGWMDGWMAVDGRGCAVPCIP KPGGSVLLSMTACSRNICVPICVDKNIYT*GLEL FKRKCHRSS*TKD*APSGF*ISRWGQGCA*RPC *VIC*GLGSIKH*AS*E

Sequence NM_004358

GCAGCCAGTCGCGGAGGCGGGGAGGCTGCGCGGTCAGAGGCGCCTGGAGCGAGCGAATCCTGGCCCACCGCCTGCCCAACCGCGTGACCTTGATTGAGTT AATGAACTTCACGCCTCAGCGTCCAGGTCTGTAAAATGGGGTGTCTAACGCAGACCGTACAGCCCAGCTGGGTTTAGCAAACTTCCGGGAGCCAGTTGGA GCCTCTCCCCATCCCTAGCGGTGATCCCAGGTGACGACATGCCGCGGGGGGTCCTGCGGAGGCCACCCTAGGGCGTTGCTGCTGCCTTTGGGAGTGTGGA GCTCCAAACCATGTCGCGAGAGGCGGATTTTGGGAGGCCGGGATCCTCGCGCCAGGGGGATGTGCGAGGGTGTGGGATAAATCTTAATTCCTCCGGCCCA CCCAAAGCCTGGAAATCCAGCCTCCGCGCCTCTTGCCCTGCGGGCCCCGCCCTCAGTCCCGCCCTCATCTAACCCGCTACCCCATTGGTGGCGTCCGGCG GCGCGGCTGCTGTTATTTTTCGAATATATAAGGAGGTGGAAGTGGCAGCTGCAACTAGAGGCTTCCCTGGCTGGTGCCTGAGCCCGGCGTCCCTCGCCCC CCGCCCTCCCCGCATCCCTCTCCTCCCTCGCGCCTGGCCCTGTGGCTCTTCCTCCCTCCCTCCTTCCCCCCCCCCCCACCCCTCGCCCGCTGCCTCCCTC GGCCCAGCCAGCTGTGCCGGCGTTTGTTGGCTGCCCTGCGCCCGGCCCTCCAGCCAGCCTTCTGCCGGCCCCGCCGCGATGGAGGTGCCCCAGCCGGAGC CCGCGCCAGGCTCGGCTCTCAGTCCAGCAGGCGTGTGCGGTGGCGCCCAGCGTCCGGGCCACCTCCCGGGCCTCCTGCTGGGATCTCATGGCCTCCTGGG GTCCCCGGTGCGGGCGGCCGCTTCCTCGCCGGTCACCACCCTCACCCAGACCATGCACGACCTCGCCGGGCTCGGCAGCCGCAGCCGCCTGACGCACCTA TCCCTGTCTCGACGGGCATCCGAATCCTCCCTGTCGTCTGAATCCTCCGAATCTTCTGATGCAGGTCTCTGCATGGATTCCCCCAGCCCTATGGACCCCC ACATGGCGGAGCAGACGTTTGAACAGGCCATCCAGGCAGCCAGCCGGATCATTCGAAACGAGCAGTTTGCCATCAGACGCTTCCAGTCTATGCCGGTGAG GCTGCTGGGCCACAGCCCCGTGCTTCGGAACATCACCAACTCCCAGGCGCCCGACGGCCGGAGGAAGAGCGAGGCGGGCAGTGGAGCTGCCAGCAGCTCT GGGGAAGACAAGGAGAATGATGGATTTGTCTTCAAGATGCCATGGAAGCCCACACATCCCAGCTCCACCCATGCTCTGGCAGAGTGGGCCAGCCGCAGGG AAGCCTTTGCCCAGAGACCCAGCTCGGCCCCCGACCTGATGTGTCTCAGTCCTGACCGGAAGATGGAAGTGGAGGAGCTCAGCCCCCTGGCCCTAGGTCG CTTCTCTCTGACCCCTGCAGAGGGGGATACTGAGGAAGATGATGGATTTGTGGACATCCTAGAGAGTGACTTAAAGGATGATGATGCAGTTCCCCCAGGC ATGGAGAGTCTCATTAGTGCCCCACTGGTCAAGACCTTGGAAAAGGAAGAGGAAAAGGACCTCGTCATGTACAGCAAGTGCCAGCGGCTCTTCCGCTCTC CGTCCATGCCCTGCAGCGTGATCCGGCCCATCCTCAAGAGGCTGGAGCGGCCCCAGGACAGGGACACGCCCGTGCAGAATAAGCGGAGGCGGAGCGTGAC CCCTCCTGAGGAGCAGCAGGAGGCTGAGGAACCTAAAGCCCGCGTCCTCCGCTCAAAATCACTGTGTCACGATGAGATCGAGAACCTCCTGGACAGTGAC CACCGAGAGCTGATTGGAGATTACTCTAAGGCCTTCCTCCTACAGACAGTAGACGGAAAGCACCAAGACCTCAAGTACATCTCACCAGAAACGATGGTGG CCCTATTGACGGGCAAGTTCAGCAACATCGTGGATAAGTTTGTGATTGTAGACTGCAGATACCCCTATGAATATGAAGGCGGGCACATCAAGACTGCGGT GAACTTGCCCCTGGAACGCGACGCCGAGAGCTTCCTACTGAAGAGCCCCATCGCGCCCTGTAGCCTGGACAAGAGAGTCATCCTCATTTTCCACTGTGAA TTCTCATCTGAGCGTGGGCCCCGCATGTGCCGTTTCATCAGGGAACGAGACCGTGCTGTCAACGACTACCCCAGCCTCTACTACCCTGAGATGTATATCC TGAAAGGCGGCTACAAGGAGTTCTTCCCTCAGCACCCGAACTTCTGTGAACCCCAGGACTACCGGCCCATGAACCACGAGGCCTTCAAGGATGAGCTAAA GACCTTCCGCCTCAAGACTCGCAGCTGGGCTGGGGAGCGGAGCCGGCGGGAGCTCTGTAGCCGGCTGCAGGACCAGTGAGGGGCCTGCGCCAGTCCTGCT ACCTCCCTTGCCTTTCGAGGCCTGAAGCCAGCTGCCCTATGGGCCTGCCGGGCTGAGGGCCTGCTGGAGGCCTCAGGTGCTGTCCATGGGAAAGATGGTG TGGGTGTCCTGCCTGTCTGCCCCAGCCCAGATTCCCCTGTGTCATCCCATCATTTTCCATATCCTGGTGCCCCCCACCCCTGGAAGAGCCCAGTCTGTTG AGTTAGTTAAGTTGGGTTAATACCAGCTTAAAGGCAGTATTTTGTGTCCTCCAGGAGCTTCTTGTTTCCTTGTTAGGGTTAACCCTTCATCTTCCTGTGT CCTGAAACGCTCCTTTGTGTGTGTGTCAGCTGAGGCTGGGGGAGAGCCGTGGTCCCTGAGGATGGGTCAGAGCTAAACTCCTTCCTGGCCTGAGAGTCAG CTCTCTGCCCTGTGTACTTCCCGGGCCAGGGCTGCCCCTAATCTCTGTAGGAACCGTGGTATGTCTGCCATGTTGCCCCTTTCTCTTTTCCCCTTTCCTG TCCCACCATACGAGCACCTCCAGCCTGAACAGAAGCTCTTACTCTTTCCTATTTCAGTGTTACCTGTGTGCTTGGTCTGTTTGACTTTACGCCCATCTCA GGACACTTCCGTAGACTGTTTAGGTTCCCCTGTCAAATATCAGTTACCCACTCGGTCCCAGTTTTGTTGCCCCAGAAAGGGATGTTATTATCCTTGGGGG CTCCCAGGGCAAGGGTTAAGGCCTGAATCATGAGCCTGCTGGAAGCCCAGCCCCTACTGCTGTGAACCCTGGGGCCTGACTGCTCAGAACTTGCTGCTGT CTTGTTGCGGATGGATGGAAGGTTGGATGGATGGGTGGATGGCCGTGGATGGCCGTGGATGCGCAGTGCCTTGCATACCCAAACCAGGTGGGAGCGTTTT GTTGAGCATGACAGCCTGCAGCAGGAATATATGTGTGCCTATTTGTGTGGACAAAAATATTTACACTTAGGGTTTGGAGCTATTCAAGAGGAAATGTCAC AGAAGCAGCTAAACCAAGGACTGAGCACCCTCTGGATTCTGAATCTCAAGATGGGGGCAGGGCTGTGCTTGAAGGCCCTGCTGAGTCATCTGTTAGGGCC TTGGTTCAATAAAGCACTGAGCAAGTTGAGAAA

refseq_CDC25B.F3 (forward primer)
refseq_CDC25B.R3 (reverse primer)
Single exon skipping

Frame 0

AASRGGGEAARSEAPGASESWPTACPTA*P*LS **TSRLSVQVCKMGCLTQTVQPSWV*QTSGSQLE PLPIPSGDPR*RHAAGGPAEATLGRCCCLWECG APNHVARGGFWEAGILAPGGCARVWDKS*FLRP TQSLEIQPPRLLPCGPRPQSRPHLTRYPIGGVRR RGCCYFSNI*GGGSGSCN*RLPWLVPEPGVPRP PPSPHPSPPSRLALWLFLPPSFPPPPPLARCLP RPSQLCRRLLAALRPALQPAFCRPRRDGGAPAGA RARLGSQSSRRVRWRPASGPPPGPPAGISWPPG VPGAGGRFLAGHHPHPDHARPRRARQPQPPDAP IPVSTGIRILPVV*ILRIF*CRSLHGFPQPYGPP HGGADV*TGHPGSQPDHSKRAVCHQTLPVYAGE AAGPQPRASEHHQLPGARRPEEERGGQWSCQQL WGRQGE*WICLQDAMEAHTSQLHPCSGRVGQPQG SLCPETQLGPRPDVSQS*PEDGSGGAQPPGPRS LLSDPCRGGY*GR*WICGHPRE*LKG**CSSPR HGESH*CPTGQDLGKGRGKGPRHVQQVPAALPLS VHALQRDPAHPQEAGAAPGQGHARAE*AEAERD PS*GAAGG*GT*SPRPPLKITVSR*DREPPGQ* PPRADWRLL*GLPPTDSRRKAPRPQVHLTRNDGG PIDGQVQQHRG*VCDCRLQIPL*I*RRAHQDCG ELAPGTRRRELPTEEPHRAL*PGQESHPHFPL* ILI*AWAPHVPFHQGTRPCCQRLPQPLLP*DVYP ERRLQGVLPSAPELL*TPGLPAHEPRGLQG*AK DLPPQDSQLGWGAEPAGAL*PAAGPVRGLRQSC YLPCLSRPEASCPMGLPG*GPAGGLRCCPWERWC GCPACLPQPRFPCVIPSFSISWCPPPLEEPSLL S*LSWVNTSLKAVFCVLQELLVSLLGLTLHLPV S*NAPLCVCQLRLGESRGP*GWVRAKLLPGLRVS SLPCVLPGPGLPLISVGTVVCLPCCPFLFSPFL SHHTSTSSLNRSSYSFLFQCYLCAWSV*LYAHL RTLP*TV*VPLSNISYPLGPSFVAPERDVIILGG SQGKG*GLNHEPAGSPAPTAVNPGA*LLRTCCC LVADGWKVGWMGGWPWMAVDAQCLAYPNQVGAF C*A*QPAAGIYVCLFVWTKIFTLRVWSYSRGNVT EAAKPRTEHPLDSESQDGGRAVLEGPAESSVRA LVQ*STEQVEK

Frame 1

QPVAEAGRLRGQRRLERANPGPPPAQPRDLD*V NELHASASRSVKWGV*RRPYSPAGFSKLPGASW SLSPSLAVIPGDDMPRGVLRRPP*GVAAAFGSVE LQTMSREADFGRPGSSRQGDVRGCGINLNSSGP PKAWKSSLRASCPAGPALSPALI*PATPLVASG GAAAVIFRIYKEVEVAAATRGFPGWCLSPASLAP RPPRIPLLPRAWPCGSSSLPPSPPPHPSPAASL GPASCAGVCWLPCARPSSQPSAGPAAMEVPQPE PAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLG SPVRAAASSPVTTLTQTMHDLAGLGSRSRLTHL SLSRRASESSLSSESSESSDAGLCMDSPSPMDP HMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVR LLGHSPVLRNITNSQAPDGRRKSEAGSGAASSS GEDKENDGFVFKMPWKPTHPSSTHALAEWASRR EAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGR FSLTPAEGDTEEDDGFVDILESDLKDDDAVPPG MESLISAPLVKTLEKEEEKDLVMYSKCQRLFRS PSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVT PPEEQQEAEEPKARVLRSKSLCHDEIENLLDSD HRELIGDYSKAFLLQTVDGKHQDLKYISPETMV ALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAV NLPLERDAESFLLKSPIAPCSLDKRVILIFHCE FSSERGPRMCRFIRERDRAVNDYPSLYYPEMYI LKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELK TFRLKTRSWAGERSRRELCSRLQDQ*GACASPA TSLAFRGLKPAALWACRAEGLLEASGAVHGKDG VGVLPVCPSPDSPVSSHHFPYPGAPHPWKSPVC* VS*VGLIPA*RQYFVSSRSFLFPC*G*PFIFLC PETLLCVCVS*GWGRAVVPEDGSELNSFLA*ES ALCPVYFPGQGCP*SL*EPWYVCHVAPFSFPLSC PTIRAPPA*TEALTLSYFSVTCVLGLFDFTPIS GHFRRLFRFPCQISVTHSVPVLLPQKGMLLSLG APRARVKA*IMSLLEAQPLLL*TLGPDCSELAAV LLRMDGRLDGWVDGRGWPWMRSALHTQTRWERF VEHDSLQQEYMCAYLCGQKYLHLGFGAIQEEMS QKQLNQGLSTLWILNLKMGAGLCLKALLSHLLGP WFNKALSKLR

Frame 2

SQSRRRGGCAVRGAWSERILAHRLPNRVTLIEL MNFTPQRPGL*NGVSNADRTAQLGLANFREPVG ASPHP*R*SQVTTCRGGSCGGHPRALLLPLGVW SSKPCRERRILGGRDPRARGMCEGVG*ILIPPAH PKPGNPASAPLALRAPPSVPPSSNPLPHWWRPA ARLLLFFEYIRRWKWQLQLEASLAGA*ARRPSP PALPASLSSLAPGPVALPPSLLPPPPTPRPLPPS AQPAVPAFVGCPAPGPPASLLPAPPRWRCPSRS PRQARLSVQQACAVAPSVRATSRASCWDLMASW GPRCGRPLPRRSPPSPRPCTTSPGSAAAAA*RTY PCLDGHPNPPCRLNPPNLLMQVSAWIPPALWTP TWRSRRLNRPSRQPAGSFETSSLPSDASSLCR* GCWATAPCFGTSPTPRRPTAGGRARRAVELPAAL GKTRRMMDLSSRCHGSPHIPAPPMLWQSGPAAG KPLPRDPARPPT*CVSVLTGRWKWRSSAPWP*V ASL*PLQRGILRKMMDLWTS*RVT*RMMMQFPQA WRVSLVPHWSRPWKRKRKRTSSCTASASGSSAL RPCPAA*SGPSSRGWSGPRTGTRPCRISGGGA* PLLRSSRRLRNLKPASSAQNHCVTMRSRTSWTVT TES*LEITLRPSSYRQ*TESTKTSSTSHQKRWW PY*RASSATSWISL*L*TADTPMNMKAGTSRLR *TCPWNATPRASY*RAPSRPVAWTRESSSFSTVN SHLSVGPACAVSSGNETVLSTTTPASTTLRCIS *KAATRSSSLSTRTSVNPRTTGP*TTRPSRMS* RPSASRLAAGLGSGAGGSSVAGCRTSEGPAPVLL PPLPFEA*SQLPYGPAGLRACWRPQVLSMGKMV WVSCLSAPAQIPLCHPIIFHILVPPTPGRAQSV ELVKLG*YQLKGSILCPPGASCFLVRVNPSSSCV LKRSFVCVSAEAGGEPWSLRMGQS*TPSWPESQ LSALCTSRARAAPNLCRNRGMSAMLPLSLFPFP VPPYEHLQPEQKLLLFPISVLPVCLVCLTLRPSQ DTSVDCLGSPVKYQLPTRSQFCCPRKGCYYPWG LPGQGLRPES*ACWKPSPYCCEPWGLTAQNLLL SCCGWMEGWMDGWMAVDGRGCAVPCIPKPGGSVL LSMTACSRNICVPICVDKNIYT*GLELFKRKCH RSS*TKD*APSGF*ISRWGQGCA*RPC*VIC*G LGSIKH*AS*E

Sequence NM_021873

GCAGCCAGTCGCGGAGGCGGGGAGGCTGCGCGGTCAGAGGCGCCTGGAGCGAGCGAATCCTGGCCCACCGCCTGCCCAACCGCGTGACCTTGATTGAGTT AATGAACTTCACGCCTCAGCGTCCAGGTCTGTAAAATGGGGTGTCTAACGCAGACCGTACAGCCCAGCTGGGTTTAGCAAACTTCCGGGAGCCAGTTGGA GCCTCTCCCCATCCCTAGCGGTGATCCCAGGTGACGACATGCCGCGGGGGGTCCTGCGGAGGCCACCCTAGGGCGTTGCTGCTGCCTTTGGGAGTGTGGA GCTCCAAACCATGTCGCGAGAGGCGGATTTTGGGAGGCCGGGATCCTCGCGCCAGGGGGATGTGCGAGGGTGTGGGATAAATCTTAATTCCTCCGGCCCA CCCAAAGCCTGGAAATCCAGCCTCCGCGCCTCTTGCCCTGCGGGCCCCGCCCTCAGTCCCGCCCTCATCTAACCCGCTACCCCATTGGTGGCGTCCGGCG GCGCGGCTGCTGTTATTTTTCGAATATATAAGGAGGTGGAAGTGGCAGCTGCAACTAGAGGCTTCCCTGGCTGGTGCCTGAGCCCGGCGTCCCTCGCCCC CCGCCCTCCCCGCATCCCTCTCCTCCCTCGCGCCTGGCCCTGTGGCTCTTCCTCCCTCCCTCCTTCCCCCCCCCCCCACCCCTCGCCCGCTGCCTCCCTC GGCCCAGCCAGCTGTGCCGGCGTTTGTTGGCTGCCCTGCGCCCGGCCCTCCAGCCAGCCTTCTGCCGGCCCCGCCGCGATGGAGGTGCCCCAGCCGGAGC CCGCGCCAGGCTCGGCTCTCAGTCCAGCAGGCGTGTGCGGTGGCGCCCAGCGTCCGGGCCACCTCCCGGGCCTCCTGCTGGGATCTCATGGCCTCCTGGG GTCCCCGGTGCGGGCGGCCGCTTCCTCGCCGGTCACCACCCTCACCCAGACCATGCACGACCTCGCCGGGCTCGGCAGCGAAACCCCAAAGAGTCAGGTA GGGACCCTGCTCTTCCGCAGCCGCAGCCGCCTGACGCACCTATCCCTGTCTCGACGGGCATCCGAATCCTCCCTGTCGTCTGAATCCTCCGAATCTTCTG ATGCAGGTCTCTGCATGGATTCCCCCAGCCCTATGGACCCCCACATGGCGGAGCAGACGTTTGAACAGGCCATCCAGGCAGCCAGCCGGATCATTCGAAA CGAGCAGTTTGCCATCAGACGCTTCCAGTCTATGCCGGTGAGGCTGCTGGGCCACAGCCCCGTGCTTCGGAACATCACCAACTCCCAGGCGCCCGACGGC CGGAGGAAGAGCGAGGCGGGCAGTGGAGCTGCCAGCAGCTCTGGGGAAGACAAGGAGAATGATGGATTTGTCTTCAAGATGCCATGGAAGCCCACACATC CCAGCTCCACCCATGCTCTGGCAGAGTGGGCCAGCCGCAGGGAAGCCTTTGCCCAGAGACCCAGCTCGGCCCCCGACCTGATGTGTCTCAGTCCTGACCG GAAGATGGAAGTGGAGGAGCTCAGCCCCCTGGCCCTAGGTCGCTTCTCTCTGACCCCTGCAGAGGGGGATACTGAGGAAGATGATGGATTTGTGGACATC CTAGAGAGTGACTTAAAGGATGATGATGCAGTTCCCCCAGGCATGGAGAGTCTCATTAGTGCCCCACTGGTCAAGACCTTGGAAAAGGAAGAGGAAAAGG ACCTCGTCATGTACAGCAAGTGCCAGCGGCTCTTCCGCTCTCCGTCCATGCCCTGCAGCGTGATCCGGCCCATCCTCAAGAGGCTGGAGCGGCCCCAGGA CAGGGACACGCCCGTGCAGAATAAGCGGAGGCGGAGCGTGACCCCTCCTGAGGAGCAGCAGGAGGCTGAGGAACCTAAAGCCCGCGTCCTCCGCTCAAAA TCACTGTGTCACGATGAGATCGAGAACCTCCTGGACAGTGACCACCGAGAGCTGATTGGAGATTACTCTAAGGCCTTCCTCCTACAGACAGTAGACGGAA AGCACCAAGACCTCAAGTACATCTCACCAGAAACGATGGTGGCCCTATTGACGGGCAAGTTCAGCAACATCGTGGATAAGTTTGTGATTGTAGACTGCAG ATACCCCTATGAATATGAAGGCGGGCACATCAAGACTGCGGTGAACTTGCCCCTGGAACGCGACGCCGAGAGCTTCCTACTGAAGAGCCCCATCGCGCCC TGTAGCCTGGACAAGAGAGTCATCCTCATTTTCCACTGTGAATTCTCATCTGAGCGTGGGCCCCGCATGTGCCGTTTCATCAGGGAACGAGACCGTGCTG TCAACGACTACCCCAGCCTCTACTACCCTGAGATGTATATCCTGAAAGGCGGCTACAAGGAGTTCTTCCCTCAGCACCCGAACTTCTGTGAACCCCAGGA CTACCGGCCCATGAACCACGAGGCCTTCAAGGATGAGCTAAAGACCTTCCGCCTCAAGACTCGCAGCTGGGCTGGGGAGCGGAGCCGGCGGGAGCTCTGT AGCCGGCTGCAGGACCAGTGAGGGGCCTGCGCCAGTCCTGCTACCTCCCTTGCCTTTCGAGGCCTGAAGCCAGCTGCCCTATGGGCCTGCCGGGCTGAGG GCCTGCTGGAGGCCTCAGGTGCTGTCCATGGGAAAGATGGTGTGGGTGTCCTGCCTGTCTGCCCCAGCCCAGATTCCCCTGTGTCATCCCATCATTTTCC ATATCCTGGTGCCCCCCACCCCTGGAAGAGCCCAGTCTGTTGAGTTAGTTAAGTTGGGTTAATACCAGCTTAAAGGCAGTATTTTGTGTCCTCCAGGAGC TTCTTGTTTCCTTGTTAGGGTTAACCCTTCATCTTCCTGTGTCCTGAAACGCTCCTTTGTGTGTGTGTCAGCTGAGGCTGGGGGAGAGCCGTGGTCCCTG AGGATGGGTCAGAGCTAAACTCCTTCCTGGCCTGAGAGTCAGCTCTCTGCCCTGTGTACTTCCCGGGCCAGGGCTGCCCCTAATCTCTGTAGGAACCGTG GTATGTCTGCCATGTTGCCCCTTTCTCTTTTCCCCTTTCCTGTCCCACCATACGAGCACCTCCAGCCTGAACAGAAGCTCTTACTCTTTCCTATTTCAGT GTTACCTGTGTGCTTGGTCTGTTTGACTTTACGCCCATCTCAGGACACTTCCGTAGACTGTTTAGGTTCCCCTGTCAAATATCAGTTACCCACTCGGTCC CAGTTTTGTTGCCCCAGAAAGGGATGTTATTATCCTTGGGGGCTCCCAGGGCAAGGGTTAAGGCCTGAATCATGAGCCTGCTGGAAGCCCAGCCCCTACT GCTGTGAACCCTGGGGCCTGACTGCTCAGAACTTGCTGCTGTCTTGTTGCGGATGGATGGAAGGTTGGATGGATGGGTGGATGGCCGTGGATGGCCGTGG ATGCGCAGTGCCTTGCATACCCAAACCAGGTGGGAGCGTTTTGTTGAGCATGACAGCCTGCAGCAGGAATATATGTGTGCCTATTTGTGTGGACAAAAAT ATTTACACTTAGGGTTTGGAGCTATTCAAGAGGAAATGTCACAGAAGCAGCTAAACCAAGGACTGAGCACCCTCTGGATTCTGAATCTCAAGATGGGGGC AGGGCTGTGCTTGAAGGCCCTGCTGAGTCATCTGTTAGGGCCTTGGTTCAATAAAGCACTGAGCAAGTTGAGAAA

refseq_CDC25B.F3 (forward primer)
refseq_CDC25B.R3 (reverse primer)
Single exon skipping

Frame 0

AASRGGGEAARSEAPGASESWPTACPTA*P*LS **TSRLSVQVCKMGCLTQTVQPSWV*QTSGSQLE PLPIPSGDPR*RHAAGGPAEATLGRCCCLWECG APNHVARGGFWEAGILAPGGCARVWDKS*FLRP TQSLEIQPPRLLPCGPRPQSRPHLTRYPIGGVRR RGCCYFSNI*GGGSGSCN*RLPWLVPEPGVPRP PPSPHPSPPSRLALWLFLPPSFPPPPPLARCLP RPSQLCRRLLAALRPALQPAFCRPRRDGGAPAGA RARLGSQSSRRVRWRPASGPPPGPPAGISWPPG VPGAGGRFLAGHHPHPDHARPRRARQRNPKESG RDPALPQPQPPDAPIPVSTGIRILPVV*ILRIF* CRSLHGFPQPYGPPHGGADV*TGHPGSQPDHSK RAVCHQTLPVYAGEAAGPQPRASEHHQLPGARR PEEERGGQWSCQQLWGRQGE*WICLQDAMEAHTS QLHPCSGRVGQPQGSLCPETQLGPRPDVSQS*P EDGSGGAQPPGPRSLLSDPCRGGY*GR*WICGH PRE*LKG**CSSPRHGESH*CPTGQDLGKGRGKG PRHVQQVPAALPLSVHALQRDPAHPQEAGAAPG QGHARAE*AEAERDPS*GAAGG*GT*SPRPPLK ITVSR*DREPPGQ*PPRADWRLL*GLPPTDSRRK APRPQVHLTRNDGGPIDGQVQQHRG*VCDCRLQ IPL*I*RRAHQDCGELAPGTRRRELPTEEPHRA L*PGQESHPHFPL*ILI*AWAPHVPFHQGTRPCC QRLPQPLLP*DVYPERRLQGVLPSAPELL*TPG LPAHEPRGLQG*AKDLPPQDSQLGWGAEPAGAL *PAAGPVRGLRQSCYLPCLSRPEASCPMGLPG*G PAGGLRCCPWERWCGCPACLPQPRFPCVIPSFS ISWCPPPLEEPSLLS*LSWVNTSLKAVFCVLQE LLVSLLGLTLHLPVS*NAPLCVCQLRLGESRGP* GWVRAKLLPGLRVSSLPCVLPGPGLPLISVGTV VCLPCCPFLFSPFLSHHTSTSSLNRSSYSFLFQ CYLCAWSV*LYAHLRTLP*TV*VPLSNISYPLGP SFVAPERDVIILGGSQGKG*GLNHEPAGSPAPT AVNPGA*LLRTCCCLVADGWKVGWMGGWPWMAV DAQCLAYPNQVGAFC*A*QPAAGIYVCLFVWTKI FTLRVWSYSRGNVTEAAKPRTEHPLDSESQDGG RAVLEGPAESSVRALVQ*STEQVEK

Frame 1

QPVAEAGRLRGQRRLERANPGPPPAQPRDLD*V NELHASASRSVKWGV*RRPYSPAGFSKLPGASW SLSPSLAVIPGDDMPRGVLRRPP*GVAAAFGSVE LQTMSREADFGRPGSSRQGDVRGCGINLNSSGP PKAWKSSLRASCPAGPALSPALI*PATPLVASG GAAAVIFRIYKEVEVAAATRGFPGWCLSPASLAP RPPRIPLLPRAWPCGSSSLPPSPPPHPSPAASL GPASCAGVCWLPCARPSSQPSAGPAAMEVPQPE PAPGSALSPAGVCGGAQRPGHLPGLLLGSHGLLG SPVRAAASSPVTTLTQTMHDLAGLGSETPKSQV GTLLFRSRSRLTHLSLSRRASESSLSSESSESS DAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRN EQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDG RRKSEAGSGAASSSGEDKENDGFVFKMPWKPTH PSSTHALAEWASRREAFAQRPSSAPDLMCLSPDR KMEVEELSPLALGRFSLTPAEGDTEEDDGFVDI LESDLKDDDAVPPGMESLISAPLVKTLEKEEEK DLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQD RDTPVQNKRRRSVTPPEEQQEAEEPKARVLRSK SLCHDEIENLLDSDHRELIGDYSKAFLLQTVDG KHQDLKYISPETMVALLTGKFSNIVDKFVIVDCR YPYEYEGGHIKTAVNLPLERDAESFLLKSPIAP CSLDKRVILIFHCEFSSERGPRMCRFIRERDRA VNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQD YRPMNHEAFKDELKTFRLKTRSWAGERSRRELC SRLQDQ*GACASPATSLAFRGLKPAALWACRAE GLLEASGAVHGKDGVGVLPVCPSPDSPVSSHHFP YPGAPHPWKSPVC*VS*VGLIPA*RQYFVSSRS FLFPC*G*PFIFLCPETLLCVCVS*GWGRAVVP EDGSELNSFLA*ESALCPVYFPGQGCP*SL*EPW YVCHVAPFSFPLSCPTIRAPPA*TEALTLSYFS VTCVLGLFDFTPISGHFRRLFRFPCQISVTHSV PVLLPQKGMLLSLGAPRARVKA*IMSLLEAQPLL L*TLGPDCSELAAVLLRMDGRLDGWVDGRGWPW MRSALHTQTRWERFVEHDSLQQEYMCAYLCGQK YLHLGFGAIQEEMSQKQLNQGLSTLWILNLKMGA GLCLKALLSHLLGPWFNKALSKLR

Frame 2

SQSRRRGGCAVRGAWSERILAHRLPNRVTLIEL MNFTPQRPGL*NGVSNADRTAQLGLANFREPVG ASPHP*R*SQVTTCRGGSCGGHPRALLLPLGVW SSKPCRERRILGGRDPRARGMCEGVG*ILIPPAH PKPGNPASAPLALRAPPSVPPSSNPLPHWWRPA ARLLLFFEYIRRWKWQLQLEASLAGA*ARRPSP PALPASLSSLAPGPVALPPSLLPPPPTPRPLPPS AQPAVPAFVGCPAPGPPASLLPAPPRWRCPSRS PRQARLSVQQACAVAPSVRATSRASCWDLMASW GPRCGRPLPRRSPPSPRPCTTSPGSAAKPQRVR* GPCSSAAAAA*RTYPCLDGHPNPPCRLNPPNLL MQVSAWIPPALWTPTWRSRRLNRPSRQPAGSFE TSSLPSDASSLCR*GCWATAPCFGTSPTPRRPTA GGRARRAVELPAALGKTRRMMDLSSRCHGSPHI PAPPMLWQSGPAAGKPLPRDPARPPT*CVSVLT GRWKWRSSAPWP*VASL*PLQRGILRKMMDLWTS *RVT*RMMMQFPQAWRVSLVPHWSRPWKRKRKR TSSCTASASGSSALRPCPAA*SGPSSRGWSGPR TGTRPCRISGGGA*PLLRSSRRLRNLKPASSAQN HCVTMRSRTSWTVTTES*LEITLRPSSYRQ*TE STKTSSTSHQKRWWPY*RASSATSWISL*L*TA DTPMNMKAGTSRLR*TCPWNATPRASY*RAPSRP VAWTRESSSFSTVNSHLSVGPACAVSSGNETVL STTTPASTTLRCIS*KAATRSSSLSTRTSVNPR TTGP*TTRPSRMS*RPSASRLAAGLGSGAGGSSV AGCRTSEGPAPVLLPPLPFEA*SQLPYGPAGLR ACWRPQVLSMGKMVWVSCLSAPAQIPLCHPIIF HILVPPTPGRAQSVELVKLG*YQLKGSILCPPGA SCFLVRVNPSSSCVLKRSFVCVSAEAGGEPWSL RMGQS*TPSWPESQLSALCTSRARAAPNLCRNR GMSAMLPLSLFPFPVPPYEHLQPEQKLLLFPISV LPVCLVCLTLRPSQDTSVDCLGSPVKYQLPTRS QFCCPRKGCYYPWGLPGQGLRPES*ACWKPSPY CCEPWGLTAQNLLLSCCGWMEGWMDGWMAVDGRG CAVPCIPKPGGSVLLSMTACSRNICVPICVDKN IYT*GLELFKRKCHRSS*TKD*APSGF*ISRWG QGCA*RPC*VIC*GLGSIKH*AS*E