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Sequences

Sequence NM_004051

CCCAGCGCGCGCTTCGCGTGTAGAAGCGTCCGGGTGGCGGAGGCCGCAGGCCGCAGGAGTGCTGGTGGAGGGGCTTCCAGAAAGACCCTGCGGCAGCGCC CCCCCTCGGCTCTCCCCGCAGGAGAGCGGGCACCTGCGCGGCGCCGGGTGAAGGCGAGAGCCTCGGCGAGCCCTCTGCAGCGGAGCCCCCTGCCCATTTG GTTTTGGAACCACCGGGAGGAACTGGGCCATTCTAACACCCGTTGCTACCATGCTGGCCACCCGCCTCTCCAGACCCCTGTCACGGCTCCCAGGAAAAAC CCTAAGTGCCTGTGATAGAGAAAATGGAGCAAGACGCCCACTATTGCTTGGTTCTACTTCCTTTATCCCGATTGGCCGTCGGACTTATGCCAGTGCGGCG GAGCCGGTTGGCAGCAAAGCTGTCCTGGTCACAGGCTGTGACTCTGGATTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTCCTTGTGTTTG CTGGCTGCTTGATGAAGGACAAAGGCCATGATGGGGTCAAGGAGCTGGACAGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAG CGAAGAGGTGGAGAAAGTGGTGGAGATTGTCCGCTCGAGCCTGAAGGACCCTGAGAAAGGCATGTGGGGCCTCGTTAACAATGCCGGCATCTCAACGTTC GGGGAGGTGGAGTTCACCAGCCTGGAGACCTACAAGCAGGTGGCAGAAGTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTCCCCCTCATCC GAAGGGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCATGGCCAACCCGGCCCGCTCCCCGTACTGCATCACCAAGTTCGGGGTAGAGGC TTTCTCGGACTGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGTCAGCGTGGTGGAGCCCGGCAACTTCATCGCTGCCACCAGCCTTTACAGCCCT GAGAGCATTCAGGCCATCGCCAAGAAGATGTGGGAGGAGCTGCCTGAGGTCGTGCGCAAGGACTACGGCAAGAAGTACTTTGATGAAAAGATCGCCAAGA TGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCGATGCTGTCACACACGCCCTGACCGCCACCACCCCCTACACCCGCTACCACCC CATGGACTACTACTGGTGGCTGCGAATGCAGATCATGACCCACTTGCCTGGAGCCATCTCCGACATGATCTACATCCGCTGAAGAGTCTCGCTGTGGCCT CTGTCAGGGATCCCTGGTGGAAGGGGAGGGGAGGGAGGAACCCATATAGTCAACTCTTGATTATCCACGTGTGGATTATCCACCATGCCAGGAAGACCCA TAACTGGTTTTAACACTAACTAGAGGGAATGACTTCTTTGCATAGTGAGTGACTTGGGCCTTCACAAACAGGGTGTGGAGTGGCAGGCAGAGGCCTCTAA ATCTCAGGGCAAACATGGTGAATCTATCTCTCCGGAGATAATTTCATACAGAGATTTTAAGAAAACATCTTTATATTAAAAACAGATCTCATTTGATCCT TAAGCCAGTCTCATGAATGAAAAGGACAGGTTTTTTTCTTTTGTAAATGAAGCATTTGCAGCTTAAAGAGGATGCATGAAATAACCCTTTTATCGCTTAT AAATAGTGCCAGTTATGTGTTCCTGCCACGGCTGTGGAAATACTTCACATTTGCATTCCAGGACTGTTTTGGATCCATTTGCCCGAGAATCTTCTGACTA ACTCTGTGTCCTCATCTGGGCAGCACACACCAAGTGCCCACTGGTACCTCTGCATGTCCATGGTGCTGTGTGACTGGCCAGCCAGCAGCCAGTGACTCAG AGCTGGCTGTATGGAGGGGGTGGGAATGTTTCTGGAGATTTTTGTTTTTCCAGACACAGTCTTGCTCAGTCCCCTAGGCTGGAGTGCAATGGCACCATCT CCGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCGGTTCTCCTGCCTCAGCCTTCCAAGTAGCTGGGGTTATAGGCACCCACCACCATGCCGGGCTAAT TTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCTAGGCTGGTCCCGAACTCCCGACTTCAAGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCT GGGATTACAGGCATGAGATTTTTACTTGAGATTTTTCCATCCTCTTTTAGGACTCAGGATAGACTTGTGTGGAGGTGCTCTCTGGCTAAGGGGATAAGTT GTTACTGGTTTGGGTCTGCTTGGTTTTGCCTTGGGTGGGGCCGGTGTCGATGGGGCAGGCTTGGCACGAGCAGTGGTGCCATGGCAGGGCACTGTGGCAT CTCCCCTAGCAGTGGATTTGGGGTCCCTGCTTGCCTCACGTGGTGCTTACACACATGTACACACACACACACACACACACACACACACACACCTTACACA CATGTACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACCCCTGTTCTGCAGGGCTTCAGCG TGGCCTTCATTCCCGCCTCGCCTCGGCCTCTTTTCAATTAAGAAGTGATGCCACTTGAGGCAGGGTCTGCATGATCACTTCTTGGGTTTCAGTTTGAAAG CTGCCATCCCTGCGACTGCCCAGGGCCTGTATGTTGGGACCGAAGCCAAACACCACTGTCCTCCAGGGGGCTTTCGGCCCGGGGCAGGGTCCCCAGTGCC CGCCTTCGAATCAGACTCCGCGTTTCCGCCTCTCCCTGGGCGGACCTGCCGCTAGAGGGCGCTCCTCCTCCGCAGCCGGCGCCGGCCTCCAGCGCCCCAG ACTCCCGCGCTGCCGCCCGAGCCTGAGGTTTCTCACGGCGTTCGGGATTCGCGCTTCGGAAACCGGGAACAAAGAAGCAAGCAGCACCCTTCAGAAACAG TGTTCTCGCTCTCCTAGCAGCTGGCCCGGGCCCGGAGGCTGGTGCCAGGAGAAGGCAGAAGAGCCCGGGCAGCCGGAGTGGGCTACGGGGTTCAGGCAGT GCCAAGGAAGAAGGGCCTCACAATGGGCAATTCAGCTGCCTCCCGGGCCGTTGTCCCCGCTGTCTTCAAACAGGGGTCCCCTGTCCCAGCTGCCCCAGGA GGAGGGGGGGAGGCAGGCAGGGCCGAAACCCTCCAGAGCCCAGAGGGGGACGCTTGGTGGCCGCTGCAGTTACATAACCATAGGATGCTTTTGTACCGTG GACCTTGTTCTAGCAGGATCCTTTCGGAATTGCACTTTTACATGTTGGGCGAATTTGTGTCCGTGCTGAAGTTTATTAAAGGAAAATAGATGGA

refseq_BDH1.F1 (forward primer)
refseq_BDH1.R1 (reverse primer)
Single exon skipping

Frame 0

PSARFACRSVRVAEAAGRRSAGGGASRKTLRQR PPSALPAGERAPARRRVKARASASPLQRSPLPIW FWNHREELGHSNTRCYHAGHPPLQTPVTAPRKN PKCL**RKWSKTPTIAWFYFLYPDWPSDLCQCG GAGWQQSCPGHRL*LWIWVLIGQASAFKRLPCVC WLLDEGQRP*WGQGAGQPKQ*PIENRPAQCLQQ RRGGESGGDCPLEPEGP*ERHVGPR*QCRHLNV RGGGVHQPGDLQAGGRSEPLGHSADDEILSPPHP KGQRPRRQYQQHAGPHGQPGPLPVLHHQVRGRG FLGLPAL*DVPPGREGQRGGARQLHRCHQPLQP *EHSGHRQEDVGGAA*GRAQGLRQEVL**KDRQD GDLLQQWLHRHVPCHRCCHTRPDRHHPLHPLPP HGLLLVAANADHDPLAWSHLRHDLHPLKSLAVA SVRDPWWKGRGGRNPYSQLLIIHVWIIHHARKTH NWF*H*LEGMTSLHSE*LGPSQTGCGVAGRGL* ISGQTW*IYLSGDNFIQRF*ENIFILKTDLI*S LSQSHE*KGQVFFFCK*SICSLKRMHEITLLSLI NSASYVFLPRLWKYFTFAFQDCFGSICPRIF*L TLCPHLGSTHQVPTGTSACPWCCVTGQPAASDS ELAVWRGWECFWRFLFFQTQSCSVP*AGVQWHHL RSLQPPPPWFKRFSCLSLPSSWGYRHPPPCRAN FCIFSRDGVSPCWLGWSRTPDFK*SACLGLPKC WDYRHEIFT*DFSILF*DSG*TCVEVLSG*GDKL LLVWVCLVLPWVGPVSMGQAWHEQWCHGRALWH LP*QWIWGPCLPHVVLTHMYTHTHTHTHTHTLH TCTHTHTHTHTHTHTHTHTHTHTHTHPCSAGLQR GLHSRLASASFQLRSDAT*GRVCMITSWVSV*K LPSLRLPRACMLGPKPNTTVLQGAFGPGQGPQC PPSNQTPRFRLSLGGPAARGRSSSAAGAGLQRPR LPRCRPSLRFLTAFGIRASETGNKEASSTLQKQ CSRSPSSWPGPGGWCQEKAEEPGQPEWATGFRQ CQGRRASQWAIQLPPGPLSPLSSNRGPLSQLPQE EGGRQAGPKPSRAQRGTLGGRCSYITIGCFCTV DLVLAGSFRNCTFTCWANLCPC*SLLKENRW

Frame 1

PARASRVEASGWRRPQAAGVLVEGLPERPCGSA PPRLSPQESGHLRGAG*RREPRRALCSGAPCPF GFGTTGRNWAILTPVATMLATRLSRPLSRLPGKT LSACDRENGARRPLLLGSTSFIPIGRRTYASAA EPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVF AGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSS EEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTF GEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLI RRAKGRVVNISSMLGRMANPARSPYCITKFGVEA FSDCLRYEMYPLGVKVSVVEPGNFIAATSLYSP ESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAK METYCSSGSTDTSPVIDAVTHALTATTPYTRYHP MDYYWWLRMQIMTHLPGAISDMIYIR*RVSLWP LSGIPGGRGGEGGTHIVNS*LSTCGLSTMPGRP ITGFNTN*RE*LLCIVSDLGLHKQGVEWQAEASK SQGKHGESISPEIISYRDFKKTSLY*KQISFDP *ASLMNEKDRFFSFVNEAFAA*RGCMK*PFYRL *IVPVMCSCHGCGNTSHLHSRTVLDPFARESSD* LCVLIWAAHTKCPLVPLHVHGAV*LASQQPVTQ SWLYGGGGNVSGDFCFSRHSLAQSPRLECNGTI SAHCNLRLPGSSGSPASAFQVAGVIGTHHHAGLI FVFLVEMGFHHVG*AGPELPTSSDPPALASQSA GITGMRFLLEIFPSSFRTQDRLVWRCSLAKGIS CYWFGSAWFCLGWGRCRWGRLGTSSGAMAGHCGI SPSSGFGVPACLTWCLHTCTHTHTHTHTHTPYT HVHTHTHTHTHTHTHTHTHTHTHTHTPVLQGFS VAFIPASPRPLFN*EVMPLEAGSA*SLLGFQFES CHPCDCPGPVCWDRSQTPLSSRGLSARGRVPSA RLRIRLRVSASPWADLPLEGAPPPQPAPASSAP DSRAAARA*GFSRRSGFALRKPGTKKQAAPFRNS VLALLAAGPGPEAGARRRQKSPGSRSGLRGSGS AKEEGPHNGQFSCLPGRCPRCLQTGVPCPSCPR RRGGGRQGRNPPEPRGGRLVAAAVT*P*DAFVPW TLF*QDPFGIALLHVGRICVRAEVY*RKIDG

Frame 2

QRALRV*KRPGGGGRRPQECWWRGFQKDPAAAP PLGSPRRRAGTCAAPGEGESLGEPSAAEPPAHL VLEPPGGTGPF*HPLLPCWPPASPDPCHGSQEK P*VPVIEKMEQDAHYCLVLLPLSRLAVGLMPVRR SRLAAKLSWSQAVTLDLGSHWPSICIQKASLCL LAA**RTKAMMGSRSWTA*TVTD*EPSSSMSAA AKRWRKWWRLSARA*RTLRKACGASLTMPASQRS GRWSSPAWRPTSRWQK*TFGAQCG*RNPFSPSS EGPKAASSISAACWAAWPTRPAPRTASPSSG*R LSRTACAMRCTPWA*RSAWWSPATSSLPPAFTAL RAFRPSPRRCGRSCLRSCARTTARSTLMKRSPR WRPTAAVAPQTRPLSSMLSHTP*PPPPPTPATT PWTTTGGCECRS*PTCLEPSPT*STSAEESRCGL CQGSLVEGEGREEPI*STLDYPRVDYPPCQEDP *LVLTLTRGNDFFA**VTWAFTNRVWSGRQRPL NLRANMVNLSLRR*FHTEILRKHLYIKNRSHLIL KPVS*MKRTGFFLL*MKHLQLKEDA*NNPFIAY K*CQLCVPATAVEILHICIPGLFWIHLPENLLT NSVSSSGQHTPSAHWYLCMSMVLCDWPASSQ*LR AGCMEGVGMFLEIFVFPDTVLLSPLGWSAMAPS PLTATSASLVQAVLLPQPSK*LGL*APTTMPG* FLYF**RWGFTMLARLVPNSRLQVIRLPWPPKVL GLQA*DFYLRFFHPLLGLRIDLCGGALWLRG*V VTGLGLLGFALGGAGVDGAGLARAVVPWQGTVA SPLAVDLGSLLASRGAYTHVHTHTHTHTHTHLTH MYTHTHTHTHTHTHTHTHTHTHTHTPLFCRASA WPSFPPRLGLFSIKK*CHLRQGLHDHFLGFSLK AAIPATAQGLYVGTEAKHHCPPGGFRPGAGSPVP AFESDSAFPPLPGRTCR*RALLLRSRRRPPAPQ TPALPPEPEVSHGVRDSRFGNREQRSKQHPSET VFSLS*QLARARRLVPGEGRRARAAGVGYGVQAV PRKKGLTMGNSAASRAVVPAVFKQGSPVPAAPG GGGEAGRAETLQSPEGDAWWPLQLHNHRMLLYR GPCSSRILSELHFYMLGEFVSVLKFIKGK*M

Sequence NM_203314

CCCAGCGCGCGCTTCGCGTGTAGAAGCGTCCGGGTGGCGGAGGCCGCAGGCCGCAGGAGTGCTGGTGGAGGGGCTTCCAGAAAGACCCTGCGGCAGCGCC CCCCCTCGGCTCTCCCCGCAGGAGAGCGGGCACCTGCGCGGCGCCGGGTGAAGGCGAGAGCCTCGGCGAGCCCTCTGCAGCGGAGCCCCCTGCCCATTTG GTTTTGGCCAGTCAGCCTGGAAATCTGCCTGTAGTCAGCTGATGCAGAGTCACCCTGCAGTTCCTACTTTGAGGGGTTGCAGAAGCACATATTTCACTAT GGAGGGCCGCCTGCAGGCCTCGCGCTGACAGGATCTTTTGTGACGCTGCAAATGTCCTGAACCACCGGGAGGAACTGGGCCATTCTAACACCCGTTGCTA CCATGCTGGCCACCCGCCTCTCCAGACCCCTGTCACGGCTCCCAGGAAAAACCCTAAGTGCCTGTGATAGAGAAAATGGAGCAAGACGCCCACTATTGCT TGGTTCTACTTCCTTTATCCCGATTGGCCGTCGGACTTATGCCAGTGCGGCGGAGCCGGTTGGCAGCAAAGCTGTCCTGGTCACAGGCTGTGACTCTGGA TTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTCCTTGTGTTTGCTGGCTGCTTGATGAAGGACAAAGGCCATGATGGGGTCAAGGAGCTGG ACAGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAGCGAAGAGGTGGAGAAAGTGGTGGAGATTGTCCGCTCGAGCCTGAAGGA CCCTGAGAAAGGCATGTGGGGCCTCGTTAACAATGCCGGCATCTCAACGTTCGGGGAGGTGGAGTTCACCAGCCTGGAGACCTACAAGCAGGTGGCAGAA GTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTCCCCCTCATCCGAAGGGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCA TGGCCAACCCGGCCCGCTCCCCGTACTGCATCACCAAGTTCGGGGTAGAGGCTTTCTCGGACTGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGT CAGCGTGGTGGAGCCCGGCAACTTCATCGCTGCCACCAGCCTTTACAGCCCTGAGAGCATTCAGGCCATCGCCAAGAAGATGTGGGAGGAGCTGCCTGAG GTCGTGCGCAAGGACTACGGCAAGAAGTACTTTGATGAAAAGATCGCCAAGATGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCG ATGCTGTCACACACGCCCTGACCGCCACCACCCCCTACACCCGCTACCACCCCATGGACTACTACTGGTGGCTGCGAATGCAGATCATGACCCACTTGCC TGGAGCCATCTCCGACATGATCTACATCCGCTGAAGAGTCTCGCTGTGGCCTCTGTCAGGGATCCCTGGTGGAAGGGGAGGGGAGGGAGGAACCCATATA GTCAACTCTTGATTATCCACGTGTGGATTATCCACCATGCCAGGAAGACCCATAACTGGTTTTAACACTAACTAGAGGGAATGACTTCTTTGCATAGTGA GTGACTTGGGCCTTCACAAACAGGGTGTGGAGTGGCAGGCAGAGGCCTCTAAATCTCAGGGCAAACATGGTGAATCTATCTCTCCGGAGATAATTTCATA CAGAGATTTTAAGAAAACATCTTTATATTAAAAACAGATCTCATTTGATCCTTAAGCCAGTCTCATGAATGAAAAGGACAGGTTTTTTTCTTTTGTAAAT GAAGCATTTGCAGCTTAAAGAGGATGCATGAAATAACCCTTTTATCGCTTATAAATAGTGCCAGTTATGTGTTCCTGCCACGGCTGTGGAAATACTTCAC ATTTGCATTCCAGGACTGTTTTGGATCCATTTGCCCGAGAATCTTCTGACTAACTCTGTGTCCTCATCTGGGCAGCACACACCAAGTGCCCACTGGTACC TCTGCATGTCCATGGTGCTGTGTGACTGGCCAGCCAGCAGCCAGTGACTCAGAGCTGGCTGTATGGAGGGGGTGGGAATGTTTCTGGAGATTTTTGTTTT TCCAGACACAGTCTTGCTCAGTCCCCTAGGCTGGAGTGCAATGGCACCATCTCCGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCGGTTCTCCTGCCT CAGCCTTCCAAGTAGCTGGGGTTATAGGCACCCACCACCATGCCGGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCTAGGCTGG TCCCGAACTCCCGACTTCAAGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGATTTTTACTTGAGATTTTTCCATCCTCTTTT AGGACTCAGGATAGACTTGTGTGGAGGTGCTCTCTGGCTAAGGGGATAAGTTGTTACTGGTTTGGGTCTGCTTGGTTTTGCCTTGGGTGGGGCCGGTGTC GATGGGGCAGGCTTGGCACGAGCAGTGGTGCCATGGCAGGGCACTGTGGCATCTCCCCTAGCAGTGGATTTGGGGTCCCTGCTTGCCTCACGTGGTGCTT ACACACATGTACACACACACACACACACACACACACACACACACCTTACACACATGTACACACACACACACACACACACACACACACACACACACACACA CACACACACACACACACACACACACACACCCCTGTTCTGCAGGGCTTCAGCGTGGCCTTCATTCCCGCCTCGCCTCGGCCTCTTTTCAATTAAGAAGTGA TGCCACTTGAGGCAGGGTCTGCATGATCACTTCTTGGGTTTCAGTTTGAAAGCTGCCATCCCTGCGACTGCCCAGGGCCTGTATGTTGGGACCGAAGCCA AACACCACTGTCCTCCAGGGGGCTTTCGGCCCGGGGCAGGGTCCCCAGTGCCCGCCTTCGAATCAGACTCCGCGTTTCCGCCTCTCCCTGGGCGGACCTG CCGCTAGAGGGCGCTCCTCCTCCGCAGCCGGCGCCGGCCTCCAGCGCCCCAGACTCCCGCGCTGCCGCCCGAGCCTGAGGTTTCTCACGGCGTTCGGGAT TCGCGCTTCGGAAACCGGGAACAAAGAAGCAAGCAGCACCCTTCAGAAACAGTGTTCTCGCTCTCCTAGCAGCTGGCCCGGGCCCGGAGGCTGGTGCCAG GAGAAGGCAGAAGAGCCCGGGCAGCCGGAGTGGGCTACGGGGTTCAGGCAGTGCCAAGGAAGAAGGGCCTCACAATGGGCAATTCAGCTGCCTCCCGGGC CGTTGTCCCCGCTGTCTTCAAACAGGGGTCCCCTGTCCCAGCTGCCCCAGGAGGAGGGGGGGAGGCAGGCAGGGCCGAAACCCTCCAGAGCCCAGAGGGG GACGCTTGGTGGCCGCTGCAGTTACATAACCATAGGATGCTTTTGTACCGTGGACCTTGTTCTAGCAGGATCCTTTCGGAATTGCACTTTTACATGTTGG GCGAATTTGTGTCCGTGCTGAAGTTTATTAAAGGAAAATAGATGGA

refseq_BDH1.F1 (forward primer)
refseq_BDH1.R1 (reverse primer)
Single exon skipping

Frame 0

PSARFACRSVRVAEAAGRRSAGGGASRKTLRQR PPSALPAGERAPARRRVKARASASPLQRSPLPIW FWPVSLEICL*SADAESPCSSYFEGLQKHIFHY GGPPAGLALTGSFVTLQMS*TTGRNWAILTPVA TMLATRLSRPLSRLPGKTLSACDRENGARRPLLL GSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSG FGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKEL DSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKD PEKGMWGLVNNAGISTFGEVEFTSLETYKQVAE VNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGR MANPARSPYCITKFGVEAFSDCLRYEMYPLGVKV SVVEPGNFIAATSLYSPESIQAIAKKMWEELPE VVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVI DAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLP GAISDMIYIR*RVSLWPLSGIPGGRGGEGGTHI VNS*LSTCGLSTMPGRPITGFNTN*RE*LLCIV SDLGLHKQGVEWQAEASKSQGKHGESISPEIISY RDFKKTSLY*KQISFDP*ASLMNEKDRFFSFVN EAFAA*RGCMK*PFYRL*IVPVMCSCHGCGNTS HLHSRTVLDPFARESSD*LCVLIWAAHTKCPLVP LHVHGAV*LASQQPVTQSWLYGGGGNVSGDFCF SRHSLAQSPRLECNGTISAHCNLRLPGSSGSPA SAFQVAGVIGTHHHAGLIFVFLVEMGFHHVG*AG PELPTSSDPPALASQSAGITGMRFLLEIFPSSF RTQDRLVWRCSLAKGISCYWFGSAWFCLGWGRC RWGRLGTSSGAMAGHCGISPSSGFGVPACLTWCL HTCTHTHTHTHTHTPYTHVHTHTHTHTHTHTHT HTHTHTHTHTPVLQGFSVAFIPASPRPLFN*EV MPLEAGSA*SLLGFQFESCHPCDCPGPVCWDRSQ TPLSSRGLSARGRVPSARLRIRLRVSASPWADL PLEGAPPPQPAPASSAPDSRAAARA*GFSRRSG FALRKPGTKKQAAPFRNSVLALLAAGPGPEAGAR RRQKSPGSRSGLRGSGSAKEEGPHNGQFSCLPG RCPRCLQTGVPCPSCPRRRGGGRQGRNPPEPRG GRLVAAAVT*P*DAFVPWTLF*QDPFGIALLHVG RICVRAEVY*RKIDG

Frame 1

PARASRVEASGWRRPQAAGVLVEGLPERPCGSA PPRLSPQESGHLRGAG*RREPRRALCSGAPCPF GFGQSAWKSACSQLMQSHPAVPTLRGCRSTYFTM EGRLQASR*QDLL*RCKCPEPPGGTGPF*HPLL PCWPPASPDPCHGSQEKP*VPVIEKMEQDAHYC LVLLPLSRLAVGLMPVRRSRLAAKLSWSQAVTLD LGSHWPSICIQKASLCLLAA**RTKAMMGSRSW TA*TVTD*EPSSSMSAAAKRWRKWWRLSARA*R TLRKACGASLTMPASQRSGRWSSPAWRPTSRWQK *TFGAQCG*RNPFSPSSEGPKAASSISAACWAA WPTRPAPRTASPSSG*RLSRTACAMRCTPWA*R SAWWSPATSSLPPAFTALRAFRPSPRRCGRSCLR SCARTTARSTLMKRSPRWRPTAAVAPQTRPLSS MLSHTP*PPPPPTPATTPWTTTGGCECRS*PTC LEPSPT*STSAEESRCGLCQGSLVEGEGREEPI* STLDYPRVDYPPCQEDP*LVLTLTRGNDFFA** VTWAFTNRVWSGRQRPLNLRANMVNLSLRR*FH TEILRKHLYIKNRSHLILKPVS*MKRTGFFLL*M KHLQLKEDA*NNPFIAYK*CQLCVPATAVEILH ICIPGLFWIHLPENLLTNSVSSSGQHTPSAHWY LCMSMVLCDWPASSQ*LRAGCMEGVGMFLEIFVF PDTVLLSPLGWSAMAPSPLTATSASLVQAVLLP QPSK*LGL*APTTMPG*FLYF**RWGFTMLARL VPNSRLQVIRLPWPPKVLGLQA*DFYLRFFHPLL GLRIDLCGGALWLRG*VVTGLGLLGFALGGAGV DGAGLARAVVPWQGTVASPLAVDLGSLLASRGA YTHVHTHTHTHTHTHLTHMYTHTHTHTHTHTHTH THTHTHTHTPLFCRASAWPSFPPRLGLFSIKK* CHLRQGLHDHFLGFSLKAAIPATAQGLYVGTEA KHHCPPGGFRPGAGSPVPAFESDSAFPPLPGRTC R*RALLLRSRRRPPAPQTPALPPEPEVSHGVRD SRFGNREQRSKQHPSETVFSLS*QLARARRLVP GEGRRARAAGVGYGVQAVPRKKGLTMGNSAASRA VVPAVFKQGSPVPAAPGGGGEAGRAETLQSPEG DAWWPLQLHNHRMLLYRGPCSSRILSELHFYML GEFVSVLKFIKGK*M

Frame 2

QRALRV*KRPGGGGRRPQECWWRGFQKDPAAAP PLGSPRRRAGTCAAPGEGESLGEPSAAEPPAHL VLASQPGNLPVVS*CRVTLQFLL*GVAEAHISL WRAACRPRADRIFCDAANVLNHREELGHSNTRCY HAGHPPLQTPVTAPRKNPKCL**RKWSKTPTIA WFYFLYPDWPSDLCQCGGAGWQQSCPGHRL*LW IWVLIGQASAFKRLPCVCWLLDEGQRP*WGQGAG QPKQ*PIENRPAQCLQQRRGGESGGDCPLEPEG P*ERHVGPR*QCRHLNVRGGGVHQPGDLQAGGR SEPLGHSADDEILSPPHPKGQRPRRQYQQHAGPH GQPGPLPVLHHQVRGRGFLGLPAL*DVPPGREG QRGGARQLHRCHQPLQP*EHSGHRQEDVGGAA* GRAQGLRQEVL**KDRQDGDLLQQWLHRHVPCHR CCHTRPDRHHPLHPLPPHGLLLVAANADHDPLA WSHLRHDLHPLKSLAVASVRDPWWKGRGGRNPY SQLLIIHVWIIHHARKTHNWF*H*LEGMTSLHSE *LGPSQTGCGVAGRGL*ISGQTW*IYLSGDNFI QRF*ENIFILKTDLI*SLSQSHE*KGQVFFFCK *SICSLKRMHEITLLSLINSASYVFLPRLWKYFT FAFQDCFGSICPRIF*LTLCPHLGSTHQVPTGT SACPWCCVTGQPAASDSELAVWRGWECFWRFLF FQTQSCSVP*AGVQWHHLRSLQPPPPWFKRFSCL SLPSSWGYRHPPPCRANFCIFSRDGVSPCWLGW SRTPDFK*SACLGLPKCWDYRHEIFT*DFSILF *DSG*TCVEVLSG*GDKLLLVWVCLVLPWVGPVS MGQAWHEQWCHGRALWHLP*QWIWGPCLPHVVL THMYTHTHTHTHTHTLHTCTHTHTHTHTHTHTH THTHTHTHTHPCSAGLQRGLHSRLASASFQLRSD AT*GRVCMITSWVSV*KLPSLRLPRACMLGPKP NTTVLQGAFGPGQGPQCPPSNQTPRFRLSLGGP AARGRSSSAAGAGLQRPRLPRCRPSLRFLTAFGI RASETGNKEASSTLQKQCSRSPSSWPGPGGWCQ EKAEEPGQPEWATGFRQCQGRRASQWAIQLPPG PLSPLSSNRGPLSQLPQEEGGRQAGPKPSRAQRG TLGGRCSYITIGCFCTVDLVLAGSFRNCTFTCW ANLCPC*SLLKENRW