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Sequences

Sequence NM_138971

ACAAGTCTTTCCGCCTCCCCAGCCCGCCCGGGAGCTGCGAGCCGCGAGCTGGATTATGGTGGCCTGAGCAGCCAACGCAGCCGCAGGAGCCCGGAGCCCT TGCCCCTGCCCGCGCCGCCGCCCGCCGGGGGGACCAGGGAAGCCGCCACCGGCCCGCCATGCCCGCCCCTCCCAGCCCCGCCGGGAGCCCGCGCCCGCTG CCCAGGCTGGCCGCCGCCGTGCCGATGTAGCGGGCTCCGGATCCCAGCCTCTCCCCTGCTCCCGTGCTCTGCGGATCTCCCCTGACCGCTCTCCACAGCC CGGACCCGGGGGCTGGCCCAGGGCCCTGCAGGCCCTGGCGTCCTGATGCCCCCAAGCTCCCTCTCCTGAGAAGCCACCAGCACCACCCAGACTTGGGGGC AGGCGCCAGGGACGGACGTGGGCCAGTGCGAGCCCAGAGGGCCCGAAGGCCGGGGCCCACCATGGCCCAAGCCCTGCCCTGGCTCCTGCTGTGGATGGGC GCGGGAGTGCTGCCTGCCCACGGCACCCAGCACGGCATCCGGCTGCCCCTGCGCAGCGGCCTGGGGGGCGCCCCCCTGGGGCTGCGGCTGCCCCGGGAGA CCGACGAAGAGCCCGAGGAGCCCGGCCGGAGGGGCAGCTTTGTGGAGATGGTGGACAACCTGAGGGGCAAGTCGGGGCAGGGCTACTACGTGGAGATGAC CGTGGGCAGCCCCCCGCAGACGCTCAACATCCTGGTGGATACAGGCAGCAGTAACTTTGCAGTGGGTGCTGCCCCCCACCCCTTCCTGCATCGCTACTAC CAGAGGCAGCTGTCCAGCACATACCGGGACCTCCGGAAGGGTGTGTATGTGCCCTACACCCAGGGCAAGTGGGAAGGGGAGCTGGGCACCGACCTGCCTG ACGACTCCCTGGAGCCTTTCTTTGACTCTCTGGTAAAGCAGACCCACGTTCCCAACCTCTTCTCCCTGCAGCTTTGTGGTGCTGGCTTCCCCCTCAACCA GTCTGAAGTGCTGGCCTCTGTCGGAGGGAGCATGATCATTGGAGGTATCGACCACTCGCTGTACACAGGCAGTCTCTGGTATACACCCATCCGGCGGGAG TGGTATTATGAGGTGATCATTGTGCGGGTGGAGATCAATGGACAGGATCTGAAAATGGACTGCAAGGAGTACAACTATGACAAGAGCATTGTGGACAGTG GCACCACCAACCTTCGTTTGCCCAAGAAAGTGTTTGAAGCTGCAGTCAAATCCATCAAGGCAGCCTCCTCCACGGAGAAGTTCCCTGATGGTTTCTGGCT AGGAGAGCAGCTGGTGTGCTGGCAAGCAGGCACCACCCCTTGGAACATTTTCCCAGTCATCTCACTCTACCTAATGGGTGAGGTTACCAACCAGTCCTTC CGCATCACCATCCTTCCGCAGCAATACCTGCGGCCAGTGGAAGATGTGGCCACGTCCCAAGACGACTGTTACAAGTTTGCCATCTCACAGTCATCCACGG GCACTGTTATGGGAGCTGTTATCATGGAGGGCTTCTACGTTGTCTTTGATCGGGCCCGAAAACGAATTGGCTTTGCTGTCAGCGCTTGCCATGTGCACGA TGAGTTCAGGACGGCAGCGGTGGAAGGCCCTTTTGTCACCTTGGACATGGAAGACTGTGGCTACAACATTCCACAGACAGATGAGTCAACCCTCATGACC ATAGCCTATGTCATGGCTGCCATCTGCGCCCTCTTCATGCTGCCACTCTGCCTCATGGTGTGTCAGTGGTGCTGCCTCCGCTGCCTGCGCCAGCAGCATG ATGACTTTGCTGATGACATCTCCCTGCTGAAGTGAGGAGGCCCATGGGCAGAAGATAGAGATTCCCCTGGACCACACCTCCGTGGTTCACTTTGGTCACA AGTAGGAGACACAGATGGCACCTGTGGCCAGAGCACCTCAGGACCCTCCCCACCCACCAAATGCCTCTGCCTTGATGGAGAAGGAAAAGGCTGGCAAGGT GGGTTCCAGGGACTGTACCTGTAGGAAACAGAAAAGAGAAGAAAGAAGCACTCTGCTGGCGGGAATACTCTTGGTCACCTCAAATTTAAGTCGGGAAATT CTGCTGCTTGAAACTTCAGCCCTGAACCTTTGTCCACCATTCCTTTAAATTCTCCAACCCAAAGTATTCTTCTTTTCTTAGTTTCAGAAGTACTGGCATC ACACGCAGGTTACCTTGGCGTGTGTCCCTGTGGTACCCTGGCAGAGAAGAGACCAAGCTTGTTTCCCTGCTGGCCAAAGTCAGTAGGAGAGGATGCACAG TTTGCTATTTGCTTTAGAGACAGGGACTGTATAAACAAGCCTAACATTGGTGCAAAGATTGCCTCTTGAATTAAAAAAAAAAACTAGATTGACTATTTAT ACAAATGGGGGCGGCTGGAAAGAGGAGAAGGAGAGGGAGTACAAAGACAGGGAATAGTGGGATCAAAGCTAGGAAAGGCAGAAACACAACCACTCACCAG TCCTAGTTTTAGACCTCATCTCCAAGATAGCATCCCATCTCAGAAGATGGGTGTTGTTTTCAATGTTTTCTTTTCTGTGGTTGCAGCCTGACCAAAAGTG AGATGGGAAGGGCTTATCTAGCCAAAGAGCTCTTTTTTAGCTCTCTTAAATGAAGTGCCCACTAAGAAGTTCCACTTAACACATGAATTTCTGCCATATT AATTTCATTGTCTCTATCTGAACCACCCTTTATTCTACATATGATAGGCAGCACTGAAATATCCTAACCCCCTAAGCTCCAGGTGCCCTGTGGGAGAGCA ACTGGACTATAGCAGGGCTGGGCTCTGTCTTCCTGGTCATAGGCTCACTCTTTCCCCCAAATCTTCCTCTGGAGCTTTGCAGCCAAGGTGCTAAAAGGAA TAGGTAGGAGACCTCTTCTATCTAATCCTTAAAAGCATAATGTTGAACATTCATTCAACAGCTGATGCCCTATAACCCCTGCCTGGATTTCTTCCTATTA GGCTATAAGAAGTAGCAAGATCTTTACATAATTCAGAGTGGTTTCATTGCCTTCCTACCCTCTCTAATGGCCCCTCCATTTATTTGACTAAAGCATCACA CAGTGGCACTAGCATTATACCAAGAGTATGAGAAATACAGTGCTTTATGGCTCTAACATTACTGCCTTCAGTATCAAGGCTGCCTGGAGAAAGGATGGCA GCCTCAGGGCTTCCTTATGTCCTCCACCACAAGAGCTCCTTGATGAAGGTCATCTTTTTCCCCTATCCTGTTCTTCCCCTCCCCGCTCCTAATGGTACGT GGGTACCCAGGCTGGTTCTTGGGCTAGGTAGTGGGGACCAAGTTCATTACCTCCCTATCAGTTCTAGCATAGTAAACTACGGTACCAGTGTTAGTGGGAA GAGCTGGGTTTTCCTAGTATACCCACTGCATCCTACTCCTACCTGGTCAACCCGCTGCTTCCAGGTATGGGACCTGCTAAGTGTGGAATTACCTGATAAG GGAGAGGGAAATACAAGGAGGGCCTCTGGTGTTCCTGGCCTCAGCCAGCTGCCCACAAGCCATAAACCAATAAAACAAGAATACTGAGTCAGTTTTTTAT CTGGGTTCTCTTCATTCCCACTGCACTTGGTGCTGCTTTGGCTGACTGGGAACACCCCATAACTACAGAGTCTGACAGGAAGACTGGAGACTGTCCACTT CTAGCTCGGAACTTACTGTGTAAATAAACTTTCAGAACTGCTACCATGAAGTGAAAATGCCACATTTTGCTTTATAATTTCTACCCATGTTGGGAAAAAC TGGCTTTTTCCCAGCCCTTTCCAGGGCATAAAACTCAACCCCTTCGATAGCAAGTCCCATCAGCCTATTATTTTTTTAAAGAAAACTTGCACTTGTTTTT CTTTTTACAGTTACTTCCTTCCTGCCCCAAAATTATAAACTCTAAGTGTAAAAAAAAGTCTTAACAACAGCTTCTTGCTTGTAAAAATATGTATTATACA TCTGTATTTTTAAATTCTGCTCCTGAAAAATGACTGTCCCATTCTCCACTCACTGCATTTGGGGCCTTTCCCATTGGTCTGCATGTCTTTTATCATTGCA GGCCAGTGGACAGAGGGAGAAGGGAGAACAGGGGTCGCCAACACTTGTGTTGCTTTCTGACTGATCCTGAACAAGAAAGAGTAACACTGAGGCGCTCGCT CCCATGCACAACTCTCCAAAACACTTATCCTCCTGCAAGAGTGGGCTTTCCAGGGTCTTTACTGGGAAGCAGTTAAGCCCCCTCCTCACCCCTTCCTTTT TTCTTTCTTTACTCCTTTGGCTTCAAAGGATTTTGGAAAAGAAACAATATGCTTTACACTCATTTTCAATTTCTAAATTTGCAGGGGATACTGAAAAATA CGGCAGGTGGCCTAAGGCTGCTGTAAAGTTGAGGGGAGAGGAAATCTTAAGATTACAAGATAAAAAACGAATCCCCTAAACAAAAAGAACAATAGAACTG GTCTTCCATTTTGCCACCTTTCCTGTTCATGACAGCTACTAACCTGGAGACAGTAACATTTCATTAACCAAAGAAAGTGGGTCACCTGACCTCTGAAGAG CTGAGTACTCAGGCCACTCCAATCACCCTACAAGATGCCAAGGAGGTCCCAGGAAGTCCAGCTCCTTAAACTGACGCTAGTCAATAAACCTGGGCAAGTG AGGCAAGAGAAATGAGGAAGAATCCATCTGTGAGGTGATAGGCAAGGATGAAAGACAAAGAAGGAAAAGAGTATCAAAGGCAGAAAGGAGATCATTTAGT TGGGTCTGAAAGGAAAAGTCTTTGCTATCCGACATGTACTGCTAGTACCTGTAAGCATTTTAGGTCCCAGAATGGAAAAAAAAATCAGCTATTGGTAATA TAATAATGTCCTTTCCCTGGAGTCAGTTTTTTTAAAAAGTTAACTCTTAGTTTTTACTTGTTTAATTCTAAAAGAGAAGGGAGCTGAGGCCATTCCCTGT AGGAGTAAAGATAAAAGGATAGGAAAAGATTCAAAGCTCTAATAGAGTCACAGCTTTCCCAGGTATAAAACCTAAAATTAAGAAGTACAATAAGCAGAGG TGGAAAATGATCTAGTTCCTGATAGCTACCCACAGAGCAAGTGATTTATAAATTTGAAATCCAAACTACTTTCTTAATATCACTTTGGTCTCCATTTTTC CCAGGACAGGAAATATGTCCCCCCCTAACTTTCTTGCTTCAAAAATTAAAATCCAGCATCCCAAGATCATTCTACAAGTAATTTTGCACAGACATCTCCT CACCCCAGTGCCTGTCTGGAGCTCACCCAAGGTCACCAAACAACTTGGTTGTGAACCAACTGCCTTAACCTTCTGGGGGAGGGGGATTAGCTAGACTAGG AGACCAGAAGTGAATGGGAAAGGGTGAGGACTTCACAATGTTGGCCTGTCAGAGCTTGATTAGAAGCCAAGACAGTGGCAGCAAAGGAAGACTTGGCCCA GGAAAAACCTGTGGGTTGTGCTAATTTCTGTCCAGAAAATAGGGTGGACAGAAGCTTGTGGGGTACATGGAGGAATTGGGACCTGGTTATGTTGTTATTC TCGGACTGTGAATTTTGGTGATGTAAAACAGAATATTCTGTAAACCTAATGTCTGTATAAATAATGAGCGTTAACACAGTAAAATATTCAATAAGAAGTC AAA

refseq_BACE1.F1 (forward primer)
refseq_BACE1.R1 (reverse primer)
Alternative donor

Frame 0

TSLSASPARPGAASRELDYGGLSSQRSRRSPEP LPLPAPPPAGGTREAATGPPCPPLPAPPGARARC PGWPPPCRCSGLRIPASPLLPCSADLP*PLSTA RTRGLAQGPAGPGVLMPPSSLS*EATSTTQTWG QAPGTDVGQCEPRGPEGRGPPWPKPCPGSCCGWA RECCLPTAPSTASGCPCAAAWGAPPWGCGCPGR PTKSPRSPAGGAALWRWWTT*GASRGRATTWR* PWAAPRRRSTSWWIQAAVTLQWVLPPTPSCIATT RGSCPAHTGTSGRVCMCPTPRASGKGSWAPTCL TTPWSLSLTLW*SRPTFPTSSPCSFVVLASPST SLKCWPLSEGA*SLEVSTTRCTQAVSGIHPSGGS GIMR*SLCGWRSMDRI*KWTARSTTMTRALWTV APPTFVCPRKCLKLQSNPSRQPPPRRSSLMVSG *ESSWCAGKQAPPLGTFSQSSHST*WVRLPTSPS ASPSFRSNTCGQWKMWPRPKTTVTSLPSHSHPR ALLWELLSWRASTLSLIGPENELALLSALAMCT MSSGRQRWKALLSPWTWKTVATTFHRQMSQPS*P *PMSWLPSAPSSCCHSASWCVSGAASAACASSM MTLLMTSPC*SEEAHGQKIEIPLDHTSVVHFGH K*ETQMAPVARAPQDPPHPPNASALMEKEKAGKV GSRDCTCRKQKREERSTLLAGILLVTSNLSREI LLLETSALNLCPPFL*ILQPKVFFFS*FQKYWH HTQVTLACVPVVPWQRRDQACFPAGQSQ*ERMHS LLFALETGTV*TSLTLVQRLPLELKKKTRLTIY TNGGGWKEEKEREYKDRE*WDQS*ERQKHNHSP VLVLDLISKIASHLRRWVLFSMFSFLWLQPDQK* DGKGLSSQRALF*LS*MKCPLRSST*HMNFCHI NFIVSI*TTLYSTYDRQH*NILTP*APGALWES NWTIAGLGSVFLVIGSLFPPNLPLELCSQGAKRN R*ETSSI*SLKA*C*TFIQQLMPYNPCLDFFLL GYKK*QDLYIIQSGFIAFLPSLMAPPFI*LKHH TVALALYQEYEKYSALWL*HYCLQYQGCLEKGWQ PQGFLMSSTTRAP**RSSFSPILFFPSPLLMVR GYPGWFLG*VVGTKFITSLSVLA**TTVPVLVG RAGFS*YTHCILLLPGQPAASRYGTC*VWNYLIR EREIQGGPLVFLASASCPQAINQ*NKNTESVFY LGSLHSHCTWCCFG*LGTPHNYRV*QEDWRLST SSSELTV*INFQNCYHEVKMPHFAL*FLPMLGKT GFFPALSRA*NSTPSIASPISLLFF*RKLALVF LFTVTSFLPQNYKL*V*KKVLTTASCL*KYVLY ICIFKFCS*KMTVPFSTHCIWGLSHWSACLLSLQ ASGQREKGEQGSPTLVLLSD*S*TRKSNTEALA PMHNSPKHLSSCKSGLSRVFTGKQLSPLLTPSF FLSLLLWLQRILEKKQYALHSFSISKFAGDTEKY GRWPKAAVKLRGEEILRLQDKKRIP*TKRTIEL VFHFATFPVHDSY*PGDSNISLTKESGSPDL*R AEYSGHSNHPTRCQGGPRKSSSLN*R*SINLGK* GKRNEEESICEVIGKDERQRRKRVSKAERRSFS WV*KEKSLLSDMYC*YL*AF*VPEWKKKSAIGN IIMSFPWSQFF*KVNS*FLLV*F*KRRELRPFPV GVKIKG*EKIQSSNRVTAFPGIKPKIKKYNKQR WKMI*FLIATHRASDL*I*NPNYFLNITLVSIF PRTGNMSPPNFLASKIKIQHPKIILQVILHRHLL TPVPVWSSPKVTKQLGCEPTALTFWGRGIS*TR RPEVNGKG*GLHNVGLSELD*KPRQWQQRKTWP RKNLWVVLISVQKIGWTEACGVHGGIGTWLCCYS RTVNFGDVKQNIL*T*CLYK**ALTQ*NIQ*EV K

Frame 1

QVFPPPQPARELRAASWIMVA*AANAAAGARSP CPCPRRRPPGGPGKPPPARHARPSQPRREPAPA AQAGRRRADVAGSGSQPLPCSRALRISPDRSPQP GPGGWPRALQALAS*CPQAPSPEKPPAPPRLGG RRQGRTWASASPEGPKAGAHHGPSPALAPAVDG RGSAACPRHPARHPAAPAQRPGGRPPGAAAAPGD RRRARGARPEGQLCGDGGQPEGQVGAGLLRGDD RGQPPADAQHPGGYRQQ*LCSGCCPPPLPASLL PEAAVQHIPGPPEGCVCALHPGQVGRGAGHRPA* RLPGAFL*LSGKADPRSQPLLPAALWCWLPPQP V*SAGLCRREHDHWRYRPLAVHRQSLVYTHPAG VVL*GDHCAGGDQWTGSENGLQGVQL*QEHCGQW HHQPSFAQESV*SCSQIHQGSLLHGEVP*WFLA RRAAGVLASRHHPLEHFPSHLTLPNG*GYQPVL PHHHPSAAIPAASGRCGHVPRRLLQVCHLTVIHG HCYGSCYHGGLLRCL*SGPKTNWLCCQRLPCAR *VQDGSGGRPFCHLGHGRLWLQHSTDR*VNPHD HSLCHGCHLRPLHAATLPHGVSVVLPPLPAPAA* *LC**HLPAEVRRPMGRR*RFPWTTPPWFTLVT SRRHRWHLWPEHLRTLPTHQMPLP*WRRKRLAR WVPGTVPVGNRKEKKEALCWREYSWSPQI*VGKF CCLKLQP*TFVHHSFKFSNPKYSSFLSFRSTGI TRRLPWRVSLWYPGREETKLVSLLAKVSRRGCT VCYLL*RQGLYKQA*HWCKDCLLN*KKKLD*LFI QMGAAGKRRRRGSTKTGNSGIKARKGRNTTTHQ S*F*TSSPR*HPISEDGCCFQCFLFCGCSLTKS EMGRAYLAKELFFSSLK*SAH*EVPLNT*ISAIL ISLSLSEPPFILHMIGSTEIS*PPKLQVPCGRA TGL*QGWALSSWS*AHSFPQIFLWSFAAKVLKG IGRRPLLSNP*KHNVEHSFNS*CPITPAWISSY* AIRSSKIFT*FRVVSLPSYPL*WPLHLFD*SIT QWH*HYTKSMRNTVLYGSNITAFSIKAAWRKDG SLRASLCPPPQELLDEGHLFPLSCSSPPRS*WYV GTQAGSWAR*WGPSSLPPYQF*HSKLRYQC*WE ELGFPSIPTASYSYLVNPLLPGMGPAKCGIT** GRGKYKEGLWCSWPQPAAHKP*TNKTRILSQFFI WVLFIPTALGAALADWEHPITTESDRKTGDCPL LARNLLCK*TFRTATMK*KCHILLYNFYPCWEK LAFSQPFPGHKTQPLR*QVPSAYYFFKENLHLFF FLQLLPSCPKIINSKCKKKS*QQLLACKNMYYT SVFLNSAPEK*LSHSPLTAFGAFPIGLHVFYHC RPVDRGRRENRGRQHLCCFLTDPEQERVTLRRSL PCTTLQNTYPPARVGFPGSLLGSS*APSSPLPF FFLYSFGFKGFWKRNNMLYTHFQFLNLQGILKN TAGGLRLL*S*GERKS*DYKIKNESPKQKEQ*NW SSILPPFLFMTATNLETVTFH*PKKVGHLTSEE LSTQATPITLQDAKEVPGSPAP*TDASQ*TWAS EAREMRKNPSVR**ARMKDKEGKEYQRQKGDHLV GSERKSLCYPTCTASTCKHFRSQNGKKNQLLVI **CPFPGVSFFKKLTLSFYLFNSKREGS*GHSL *E*R*KDRKRFKALIESQLSQV*NLKLRSTISRG GK*SSS**LPTEQVIYKFEIQTTFLISLWSPFF PGQEICPPLTFLLQKLKSSIPRSFYK*FCTDIS SPQCLSGAHPRSPNNLVVNQLP*PSGGGGLARLG DQK*MGKGEDFTMLACQSLIRSQDSGSKGRLGP GKTCGLC*FLSRK*GGQKLVGYMEELGPGYVVI LGL*ILVM*NRIFCKPNVCINNER*HSKIFNKKS

Frame 2

KSFRLPSPPGSCEPRAGLWWPEQPTQPQEPGAL APARAAARRGDQGSRHRPAMPAPPSPAGSPRPL PRLAAAVPM*RAPDPSLSPAPVLCGSPLTALHS PDPGAGPGPCRPWRPDAPKLPLLRSHQHHPDLGA GARDGRGPVRAQRARRPGPTMAQALPWLLLWMG AGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRE TDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMT VGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLP DDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQ SEVLASVGGSMIIGGIDHSLYTGSLWYTPIRRE WYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDS GTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWL GEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSF RITILPQQYLRPVEDVATSQDDCYKFAISQSST GTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHD EFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMT IAYVMAAICALFMLPLCLMVCQWCCLRCLRQQH DDFADDISLLK*GGPWAEDRDSPGPHLRGSLWSQ VGDTDGTCGQSTSGPSPPTKCLCLDGEGKGWQG GFQGLYL*ETEKRRKKHSAGGNTLGHLKFKSGN SAA*NFSPEPLSTIPLNSPTQSILLFLVSEVLAS HAGYLGVCPCGTLAEKRPSLFPCWPKSVGEDAQ FAICFRDRDCINKPNIGAKIAS*IKKKN*IDYL YKWGRLERGEGEGVQRQGIVGSKLGKAETQPLTS PSFRPHLQDSIPSQKMGVVFNVFFSVVAA*PKV RWEGLI*PKSSFLALLNEVPTKKFHLTHEFLPY *FHCLYLNHPLFYI**AALKYPNPLSSRCPVGEQ LDYSRAGLCLPGHRLTLSPKSSSGALQPRC*KE *VGDLFYLILKSIMLNIHSTADAL*PLPGFLPI RL*EVARSLHNSEWFHCLPTLSNGPSIYLTKASH SGTSIIPRV*EIQCFMALTLLPSVSRLPGERMA ASGLPYVLHHKSSLMKVIFFPYPVLPLPAPNGT WVPRLVLGLGSGDQVHYLPISSSIVNYGTSVSGK SWVFLVYPLHPTPTWSTRCFQVWDLLSVELPDK GEGNTRRASGVPGLSQLPTSHKPIKQEY*VSFL SGFSSFPLHLVLLWLTGNTP*LQSLTGRLETVHF *LGTYCVNKLSELLP*SENATFCFIISTHVGKN WLFPSPFQGIKLNPFDSKSHQPIIFLKKTCTCF SFYSYFLPAPKL*TLSVKKSLNNSFLLVKICIIH LYF*ILLLKNDCPILHSLHLGPFPLVCMSFIIA GQWTEGEGRTGVANTCVAF*LILNKKE*H*GAR SHAQLSKTLILLQEWAFQGLYWEAVKPPPHPFLF SFFTPLASKDFGKETICFTLIFNF*ICRGY*KI RQVA*GCCKVEGRGNLKITR*KTNPLNKKNNRT GLPFCHLSCS*QLLTWRQ*HFINQRKWVT*PLKS *VLRPLQSPYKMPRRSQEVQLLKLTLVNKPGQV RQEK*GRIHL*GDRQG*KTKKEKSIKGRKEII* LGLKGKVFAIRHVLLVPVSILGPRMEKKISYW*Y NNVLSLESVFLKS*LLVFTCLILKEKGAEAIPC RSKDKRIGKDSKL**SHSFPRYKT*N*EVQ*AE VENDLVPDSYPQSK*FINLKSKLLS*YHFGLHFS QDRKYVPP*LSCFKN*NPASQDHSTSNFAQTSP HPSACLELTQGHQTTWL*TNCLNLLGEGD*LD* ETRSEWERVRTSQCWPVRA*LEAKTVAAKEDLAQ EKPVGCANFCPENRVDRSLWGTWRNWDLVMLLF SDCEFW*CKTEYSVNLMSV*IMSVNTVKYSIRS Q

Sequence NM_012104

ACAAGTCTTTCCGCCTCCCCAGCCCGCCCGGGAGCTGCGAGCCGCGAGCTGGATTATGGTGGCCTGAGCAGCCAACGCAGCCGCAGGAGCCCGGAGCCCT TGCCCCTGCCCGCGCCGCCGCCCGCCGGGGGGACCAGGGAAGCCGCCACCGGCCCGCCATGCCCGCCCCTCCCAGCCCCGCCGGGAGCCCGCGCCCGCTG CCCAGGCTGGCCGCCGCCGTGCCGATGTAGCGGGCTCCGGATCCCAGCCTCTCCCCTGCTCCCGTGCTCTGCGGATCTCCCCTGACCGCTCTCCACAGCC CGGACCCGGGGGCTGGCCCAGGGCCCTGCAGGCCCTGGCGTCCTGATGCCCCCAAGCTCCCTCTCCTGAGAAGCCACCAGCACCACCCAGACTTGGGGGC AGGCGCCAGGGACGGACGTGGGCCAGTGCGAGCCCAGAGGGCCCGAAGGCCGGGGCCCACCATGGCCCAAGCCCTGCCCTGGCTCCTGCTGTGGATGGGC GCGGGAGTGCTGCCTGCCCACGGCACCCAGCACGGCATCCGGCTGCCCCTGCGCAGCGGCCTGGGGGGCGCCCCCCTGGGGCTGCGGCTGCCCCGGGAGA CCGACGAAGAGCCCGAGGAGCCCGGCCGGAGGGGCAGCTTTGTGGAGATGGTGGACAACCTGAGGGGCAAGTCGGGGCAGGGCTACTACGTGGAGATGAC CGTGGGCAGCCCCCCGCAGACGCTCAACATCCTGGTGGATACAGGCAGCAGTAACTTTGCAGTGGGTGCTGCCCCCCACCCCTTCCTGCATCGCTACTAC CAGAGGCAGCTGTCCAGCACATACCGGGACCTCCGGAAGGGTGTGTATGTGCCCTACACCCAGGGCAAGTGGGAAGGGGAGCTGGGCACCGACCTGGTAA GCATCCCCCATGGCCCCAACGTCACTGTGCGTGCCAACATTGCTGCCATCACTGAATCAGACAAGTTCTTCATCAACGGCTCCAACTGGGAAGGCATCCT GGGGCTGGCCTATGCTGAGATTGCCAGGCCTGACGACTCCCTGGAGCCTTTCTTTGACTCTCTGGTAAAGCAGACCCACGTTCCCAACCTCTTCTCCCTG CAGCTTTGTGGTGCTGGCTTCCCCCTCAACCAGTCTGAAGTGCTGGCCTCTGTCGGAGGGAGCATGATCATTGGAGGTATCGACCACTCGCTGTACACAG GCAGTCTCTGGTATACACCCATCCGGCGGGAGTGGTATTATGAGGTGATCATTGTGCGGGTGGAGATCAATGGACAGGATCTGAAAATGGACTGCAAGGA GTACAACTATGACAAGAGCATTGTGGACAGTGGCACCACCAACCTTCGTTTGCCCAAGAAAGTGTTTGAAGCTGCAGTCAAATCCATCAAGGCAGCCTCC TCCACGGAGAAGTTCCCTGATGGTTTCTGGCTAGGAGAGCAGCTGGTGTGCTGGCAAGCAGGCACCACCCCTTGGAACATTTTCCCAGTCATCTCACTCT ACCTAATGGGTGAGGTTACCAACCAGTCCTTCCGCATCACCATCCTTCCGCAGCAATACCTGCGGCCAGTGGAAGATGTGGCCACGTCCCAAGACGACTG TTACAAGTTTGCCATCTCACAGTCATCCACGGGCACTGTTATGGGAGCTGTTATCATGGAGGGCTTCTACGTTGTCTTTGATCGGGCCCGAAAACGAATT GGCTTTGCTGTCAGCGCTTGCCATGTGCACGATGAGTTCAGGACGGCAGCGGTGGAAGGCCCTTTTGTCACCTTGGACATGGAAGACTGTGGCTACAACA TTCCACAGACAGATGAGTCAACCCTCATGACCATAGCCTATGTCATGGCTGCCATCTGCGCCCTCTTCATGCTGCCACTCTGCCTCATGGTGTGTCAGTG GTGCTGCCTCCGCTGCCTGCGCCAGCAGCATGATGACTTTGCTGATGACATCTCCCTGCTGAAGTGAGGAGGCCCATGGGCAGAAGATAGAGATTCCCCT GGACCACACCTCCGTGGTTCACTTTGGTCACAAGTAGGAGACACAGATGGCACCTGTGGCCAGAGCACCTCAGGACCCTCCCCACCCACCAAATGCCTCT GCCTTGATGGAGAAGGAAAAGGCTGGCAAGGTGGGTTCCAGGGACTGTACCTGTAGGAAACAGAAAAGAGAAGAAAGAAGCACTCTGCTGGCGGGAATAC TCTTGGTCACCTCAAATTTAAGTCGGGAAATTCTGCTGCTTGAAACTTCAGCCCTGAACCTTTGTCCACCATTCCTTTAAATTCTCCAACCCAAAGTATT CTTCTTTTCTTAGTTTCAGAAGTACTGGCATCACACGCAGGTTACCTTGGCGTGTGTCCCTGTGGTACCCTGGCAGAGAAGAGACCAAGCTTGTTTCCCT GCTGGCCAAAGTCAGTAGGAGAGGATGCACAGTTTGCTATTTGCTTTAGAGACAGGGACTGTATAAACAAGCCTAACATTGGTGCAAAGATTGCCTCTTG AATTAAAAAAAAAAACTAGATTGACTATTTATACAAATGGGGGCGGCTGGAAAGAGGAGAAGGAGAGGGAGTACAAAGACAGGGAATAGTGGGATCAAAG CTAGGAAAGGCAGAAACACAACCACTCACCAGTCCTAGTTTTAGACCTCATCTCCAAGATAGCATCCCATCTCAGAAGATGGGTGTTGTTTTCAATGTTT TCTTTTCTGTGGTTGCAGCCTGACCAAAAGTGAGATGGGAAGGGCTTATCTAGCCAAAGAGCTCTTTTTTAGCTCTCTTAAATGAAGTGCCCACTAAGAA GTTCCACTTAACACATGAATTTCTGCCATATTAATTTCATTGTCTCTATCTGAACCACCCTTTATTCTACATATGATAGGCAGCACTGAAATATCCTAAC CCCCTAAGCTCCAGGTGCCCTGTGGGAGAGCAACTGGACTATAGCAGGGCTGGGCTCTGTCTTCCTGGTCATAGGCTCACTCTTTCCCCCAAATCTTCCT CTGGAGCTTTGCAGCCAAGGTGCTAAAAGGAATAGGTAGGAGACCTCTTCTATCTAATCCTTAAAAGCATAATGTTGAACATTCATTCAACAGCTGATGC CCTATAACCCCTGCCTGGATTTCTTCCTATTAGGCTATAAGAAGTAGCAAGATCTTTACATAATTCAGAGTGGTTTCATTGCCTTCCTACCCTCTCTAAT GGCCCCTCCATTTATTTGACTAAAGCATCACACAGTGGCACTAGCATTATACCAAGAGTATGAGAAATACAGTGCTTTATGGCTCTAACATTACTGCCTT CAGTATCAAGGCTGCCTGGAGAAAGGATGGCAGCCTCAGGGCTTCCTTATGTCCTCCACCACAAGAGCTCCTTGATGAAGGTCATCTTTTTCCCCTATCC TGTTCTTCCCCTCCCCGCTCCTAATGGTACGTGGGTACCCAGGCTGGTTCTTGGGCTAGGTAGTGGGGACCAAGTTCATTACCTCCCTATCAGTTCTAGC ATAGTAAACTACGGTACCAGTGTTAGTGGGAAGAGCTGGGTTTTCCTAGTATACCCACTGCATCCTACTCCTACCTGGTCAACCCGCTGCTTCCAGGTAT GGGACCTGCTAAGTGTGGAATTACCTGATAAGGGAGAGGGAAATACAAGGAGGGCCTCTGGTGTTCCTGGCCTCAGCCAGCTGCCCACAAGCCATAAACC AATAAAACAAGAATACTGAGTCAGTTTTTTATCTGGGTTCTCTTCATTCCCACTGCACTTGGTGCTGCTTTGGCTGACTGGGAACACCCCATAACTACAG AGTCTGACAGGAAGACTGGAGACTGTCCACTTCTAGCTCGGAACTTACTGTGTAAATAAACTTTCAGAACTGCTACCATGAAGTGAAAATGCCACATTTT GCTTTATAATTTCTACCCATGTTGGGAAAAACTGGCTTTTTCCCAGCCCTTTCCAGGGCATAAAACTCAACCCCTTCGATAGCAAGTCCCATCAGCCTAT TATTTTTTTAAAGAAAACTTGCACTTGTTTTTCTTTTTACAGTTACTTCCTTCCTGCCCCAAAATTATAAACTCTAAGTGTAAAAAAAAGTCTTAACAAC AGCTTCTTGCTTGTAAAAATATGTATTATACATCTGTATTTTTAAATTCTGCTCCTGAAAAATGACTGTCCCATTCTCCACTCACTGCATTTGGGGCCTT TCCCATTGGTCTGCATGTCTTTTATCATTGCAGGCCAGTGGACAGAGGGAGAAGGGAGAACAGGGGTCGCCAACACTTGTGTTGCTTTCTGACTGATCCT GAACAAGAAAGAGTAACACTGAGGCGCTCGCTCCCATGCACAACTCTCCAAAACACTTATCCTCCTGCAAGAGTGGGCTTTCCAGGGTCTTTACTGGGAA GCAGTTAAGCCCCCTCCTCACCCCTTCCTTTTTTCTTTCTTTACTCCTTTGGCTTCAAAGGATTTTGGAAAAGAAACAATATGCTTTACACTCATTTTCA ATTTCTAAATTTGCAGGGGATACTGAAAAATACGGCAGGTGGCCTAAGGCTGCTGTAAAGTTGAGGGGAGAGGAAATCTTAAGATTACAAGATAAAAAAC GAATCCCCTAAACAAAAAGAACAATAGAACTGGTCTTCCATTTTGCCACCTTTCCTGTTCATGACAGCTACTAACCTGGAGACAGTAACATTTCATTAAC CAAAGAAAGTGGGTCACCTGACCTCTGAAGAGCTGAGTACTCAGGCCACTCCAATCACCCTACAAGATGCCAAGGAGGTCCCAGGAAGTCCAGCTCCTTA AACTGACGCTAGTCAATAAACCTGGGCAAGTGAGGCAAGAGAAATGAGGAAGAATCCATCTGTGAGGTGATAGGCAAGGATGAAAGACAAAGAAGGAAAA GAGTATCAAAGGCAGAAAGGAGATCATTTAGTTGGGTCTGAAAGGAAAAGTCTTTGCTATCCGACATGTACTGCTAGTACCTGTAAGCATTTTAGGTCCC AGAATGGAAAAAAAAATCAGCTATTGGTAATATAATAATGTCCTTTCCCTGGAGTCAGTTTTTTTAAAAAGTTAACTCTTAGTTTTTACTTGTTTAATTC TAAAAGAGAAGGGAGCTGAGGCCATTCCCTGTAGGAGTAAAGATAAAAGGATAGGAAAAGATTCAAAGCTCTAATAGAGTCACAGCTTTCCCAGGTATAA AACCTAAAATTAAGAAGTACAATAAGCAGAGGTGGAAAATGATCTAGTTCCTGATAGCTACCCACAGAGCAAGTGATTTATAAATTTGAAATCCAAACTA CTTTCTTAATATCACTTTGGTCTCCATTTTTCCCAGGACAGGAAATATGTCCCCCCCTAACTTTCTTGCTTCAAAAATTAAAATCCAGCATCCCAAGATC ATTCTACAAGTAATTTTGCACAGACATCTCCTCACCCCAGTGCCTGTCTGGAGCTCACCCAAGGTCACCAAACAACTTGGTTGTGAACCAACTGCCTTAA CCTTCTGGGGGAGGGGGATTAGCTAGACTAGGAGACCAGAAGTGAATGGGAAAGGGTGAGGACTTCACAATGTTGGCCTGTCAGAGCTTGATTAGAAGCC AAGACAGTGGCAGCAAAGGAAGACTTGGCCCAGGAAAAACCTGTGGGTTGTGCTAATTTCTGTCCAGAAAATAGGGTGGACAGAAGCTTGTGGGGTACAT GGAGGAATTGGGACCTGGTTATGTTGTTATTCTCGGACTGTGAATTTTGGTGATGTAAAACAGAATATTCTGTAAACCTAATGTCTGTATAAATAATGAG CGTTAACACAGTAAAATATTCAATAAGAAGTCAAA

refseq_BACE1.F1 (forward primer)
refseq_BACE1.R1 (reverse primer)
Alternative donor

Frame 0

TSLSASPARPGAASRELDYGGLSSQRSRRSPEP LPLPAPPPAGGTREAATGPPCPPLPAPPGARARC PGWPPPCRCSGLRIPASPLLPCSADLP*PLSTA RTRGLAQGPAGPGVLMPPSSLS*EATSTTQTWG QAPGTDVGQCEPRGPEGRGPPWPKPCPGSCCGWA RECCLPTAPSTASGCPCAAAWGAPPWGCGCPGR PTKSPRSPAGGAALWRWWTT*GASRGRATTWR* PWAAPRRRSTSWWIQAAVTLQWVLPPTPSCIATT RGSCPAHTGTSGRVCMCPTPRASGKGSWAPTW* ASPMAPTSLCVPTLLPSLNQTSSSSTAPTGKAS WGWPMLRLPGLTTPWSLSLTLW*SRPTFPTSSPC SFVVLASPSTSLKCWPLSEGA*SLEVSTTRCTQ AVSGIHPSGGSGIMR*SLCGWRSMDRI*KWTAR STTMTRALWTVAPPTFVCPRKCLKLQSNPSRQPP PRRSSLMVSG*ESSWCAGKQAPPLGTFSQSSHS T*WVRLPTSPSASPSFRSNTCGQWKMWPRPKTT VTSLPSHSHPRALLWELLSWRASTLSLIGPENEL ALLSALAMCTMSSGRQRWKALLSPWTWKTVATT FHRQMSQPS*P*PMSWLPSAPSSCCHSASWCVS GAASAACASSMMTLLMTSPC*SEEAHGQKIEIPL DHTSVVHFGHK*ETQMAPVARAPQDPPHPPNAS ALMEKEKAGKVGSRDCTCRKQKREERSTLLAGI LLVTSNLSREILLLETSALNLCPPFL*ILQPKVF FFS*FQKYWHHTQVTLACVPVVPWQRRDQACFP AGQSQ*ERMHSLLFALETGTV*TSLTLVQRLPL ELKKKTRLTIYTNGGGWKEEKEREYKDRE*WDQS *ERQKHNHSPVLVLDLISKIASHLRRWVLFSMF SFLWLQPDQK*DGKGLSSQRALF*LS*MKCPLR SST*HMNFCHINFIVSI*TTLYSTYDRQH*NILT P*APGALWESNWTIAGLGSVFLVIGSLFPPNLP LELCSQGAKRNR*ETSSI*SLKA*C*TFIQQLM PYNPCLDFFLLGYKK*QDLYIIQSGFIAFLPSLM APPFI*LKHHTVALALYQEYEKYSALWL*HYCL QYQGCLEKGWQPQGFLMSSTTRAP**RSSFSPI LFFPSPLLMVRGYPGWFLG*VVGTKFITSLSVLA **TTVPVLVGRAGFS*YTHCILLLPGQPAASRY GTC*VWNYLIREREIQGGPLVFLASASCPQAIN Q*NKNTESVFYLGSLHSHCTWCCFG*LGTPHNYR V*QEDWRLSTSSSELTV*INFQNCYHEVKMPHF AL*FLPMLGKTGFFPALSRA*NSTPSIASPISL LFF*RKLALVFLFTVTSFLPQNYKL*V*KKVLTT ASCL*KYVLYICIFKFCS*KMTVPFSTHCIWGL SHWSACLLSLQASGQREKGEQGSPTLVLLSD*S *TRKSNTEALAPMHNSPKHLSSCKSGLSRVFTGK QLSPLLTPSFFLSLLLWLQRILEKKQYALHSFS ISKFAGDTEKYGRWPKAAVKLRGEEILRLQDKK RIP*TKRTIELVFHFATFPVHDSY*PGDSNISLT KESGSPDL*RAEYSGHSNHPTRCQGGPRKSSSL N*R*SINLGK*GKRNEEESICEVIGKDERQRRK RVSKAERRSFSWV*KEKSLLSDMYC*YL*AF*VP EWKKKSAIGNIIMSFPWSQFF*KVNS*FLLV*F *KRRELRPFPVGVKIKG*EKIQSSNRVTAFPGI KPKIKKYNKQRWKMI*FLIATHRASDL*I*NPNY FLNITLVSIFPRTGNMSPPNFLASKIKIQHPKI ILQVILHRHLLTPVPVWSSPKVTKQLGCEPTAL TFWGRGIS*TRRPEVNGKG*GLHNVGLSELD*KP RQWQQRKTWPRKNLWVVLISVQKIGWTEACGVH GGIGTWLCCYSRTVNFGDVKQNIL*T*CLYK** ALTQ*NIQ*EVK

Frame 1

QVFPPPQPARELRAASWIMVA*AANAAAGARSP CPCPRRRPPGGPGKPPPARHARPSQPRREPAPA AQAGRRRADVAGSGSQPLPCSRALRISPDRSPQP GPGGWPRALQALAS*CPQAPSPEKPPAPPRLGG RRQGRTWASASPEGPKAGAHHGPSPALAPAVDG RGSAACPRHPARHPAAPAQRPGGRPPGAAAAPGD RRRARGARPEGQLCGDGGQPEGQVGAGLLRGDD RGQPPADAQHPGGYRQQ*LCSGCCPPPLPASLL PEAAVQHIPGPPEGCVCALHPGQVGRGAGHRPGK HPPWPQRHCACQHCCHH*IRQVLHQRLQLGRHP GAGLC*DCQA*RLPGAFL*LSGKADPRSQPLLP AALWCWLPPQPV*SAGLCRREHDHWRYRPLAVHR QSLVYTHPAGVVL*GDHCAGGDQWTGSENGLQG VQL*QEHCGQWHHQPSFAQESV*SCSQIHQGSL LHGEVP*WFLARRAAGVLASRHHPLEHFPSHLTL PNG*GYQPVLPHHHPSAAIPAASGRCGHVPRRL LQVCHLTVIHGHCYGSCYHGGLLRCL*SGPKTN WLCCQRLPCAR*VQDGSGGRPFCHLGHGRLWLQH STDR*VNPHDHSLCHGCHLRPLHAATLPHGVSV VLPPLPAPAA**LC**HLPAEVRRPMGRR*RFP WTTPPWFTLVTSRRHRWHLWPEHLRTLPTHQMPL P*WRRKRLARWVPGTVPVGNRKEKKEALCWREY SWSPQI*VGKFCCLKLQP*TFVHHSFKFSNPKY SSFLSFRSTGITRRLPWRVSLWYPGREETKLVSL LAKVSRRGCTVCYLL*RQGLYKQA*HWCKDCLL N*KKKLD*LFIQMGAAGKRRRRGSTKTGNSGIK ARKGRNTTTHQS*F*TSSPR*HPISEDGCCFQCF LFCGCSLTKSEMGRAYLAKELFFSSLK*SAH*E VPLNT*ISAILISLSLSEPPFILHMIGSTEIS* PPKLQVPCGRATGL*QGWALSSWS*AHSFPQIFL WSFAAKVLKGIGRRPLLSNP*KHNVEHSFNS*C PITPAWISSY*AIRSSKIFT*FRVVSLPSYPL* WPLHLFD*SITQWH*HYTKSMRNTVLYGSNITAF SIKAAWRKDGSLRASLCPPPQELLDEGHLFPLS CSSPPRS*WYVGTQAGSWAR*WGPSSLPPYQF* HSKLRYQC*WEELGFPSIPTASYSYLVNPLLPGM GPAKCGIT**GRGKYKEGLWCSWPQPAAHKP*T NKTRILSQFFIWVLFIPTALGAALADWEHPITT ESDRKTGDCPLLARNLLCK*TFRTATMK*KCHIL LYNFYPCWEKLAFSQPFPGHKTQPLR*QVPSAY YFFKENLHLFFFLQLLPSCPKIINSKCKKKS*Q QLLACKNMYYTSVFLNSAPEK*LSHSPLTAFGAF PIGLHVFYHCRPVDRGRRENRGRQHLCCFLTDP EQERVTLRRSLPCTTLQNTYPPARVGFPGSLLG SS*APSSPLPFFFLYSFGFKGFWKRNNMLYTHFQ FLNLQGILKNTAGGLRLL*S*GERKS*DYKIKN ESPKQKEQ*NWSSILPPFLFMTATNLETVTFH* PKKVGHLTSEELSTQATPITLQDAKEVPGSPAP* TDASQ*TWASEAREMRKNPSVR**ARMKDKEGK EYQRQKGDHLVGSERKSLCYPTCTASTCKHFRS QNGKKNQLLVI**CPFPGVSFFKKLTLSFYLFNS KREGS*GHSL*E*R*KDRKRFKALIESQLSQV* NLKLRSTISRGGK*SSS**LPTEQVIYKFEIQT TFLISLWSPFFPGQEICPPLTFLLQKLKSSIPRS FYK*FCTDISSPQCLSGAHPRSPNNLVVNQLP* PSGGGGLARLGDQK*MGKGEDFTMLACQSLIRS QDSGSKGRLGPGKTCGLC*FLSRK*GGQKLVGYM EELGPGYVVILGL*ILVM*NRIFCKPNVCINNE R*HSKIFNKKS

Frame 2

KSFRLPSPPGSCEPRAGLWWPEQPTQPQEPGAL APARAAARRGDQGSRHRPAMPAPPSPAGSPRPL PRLAAAVPM*RAPDPSLSPAPVLCGSPLTALHS PDPGAGPGPCRPWRPDAPKLPLLRSHQHHPDLGA GARDGRGPVRAQRARRPGPTMAQALPWLLLWMG AGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRE TDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMT VGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYY QRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLV SIPHGPNVTVRANIAAITESDKFFINGSNWEGIL GLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSL QLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYT GSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKE YNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAAS STEKFPDGFWLGEQLVCWQAGTTPWNIFPVISL YLMGEVTNQSFRITILPQQYLRPVEDVATSQDDC YKFAISQSSTGTVMGAVIMEGFYVVFDRARKRI GFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN IPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW CCLRCLRQQHDDFADDISLLK*GGPWAEDRDSP GPHLRGSLWSQVGDTDGTCGQSTSGPSPPTKCL CLDGEGKGWQGGFQGLYL*ETEKRRKKHSAGGNT LGHLKFKSGNSAA*NFSPEPLSTIPLNSPTQSI LLFLVSEVLASHAGYLGVCPCGTLAEKRPSLFP CWPKSVGEDAQFAICFRDRDCINKPNIGAKIAS* IKKKN*IDYLYKWGRLERGEGEGVQRQGIVGSK LGKAETQPLTSPSFRPHLQDSIPSQKMGVVFNV FFSVVAA*PKVRWEGLI*PKSSFLALLNEVPTKK FHLTHEFLPY*FHCLYLNHPLFYI**AALKYPN PLSSRCPVGEQLDYSRAGLCLPGHRLTLSPKSS SGALQPRC*KE*VGDLFYLILKSIMLNIHSTADA L*PLPGFLPIRL*EVARSLHNSEWFHCLPTLSN GPSIYLTKASHSGTSIIPRV*EIQCFMALTLLP SVSRLPGERMAASGLPYVLHHKSSLMKVIFFPYP VLPLPAPNGTWVPRLVLGLGSGDQVHYLPISSS IVNYGTSVSGKSWVFLVYPLHPTPTWSTRCFQV WDLLSVELPDKGEGNTRRASGVPGLSQLPTSHKP IKQEY*VSFLSGFSSFPLHLVLLWLTGNTP*LQ SLTGRLETVHF*LGTYCVNKLSELLP*SENATF CFIISTHVGKNWLFPSPFQGIKLNPFDSKSHQPI IFLKKTCTCFSFYSYFLPAPKL*TLSVKKSLNN SFLLVKICIIHLYF*ILLLKNDCPILHSLHLGP FPLVCMSFIIAGQWTEGEGRTGVANTCVAF*LIL NKKE*H*GARSHAQLSKTLILLQEWAFQGLYWE AVKPPPHPFLFSFFTPLASKDFGKETICFTLIF NF*ICRGY*KIRQVA*GCCKVEGRGNLKITR*KT NPLNKKNNRTGLPFCHLSCS*QLLTWRQ*HFIN QRKWVT*PLKS*VLRPLQSPYKMPRRSQEVQLL KLTLVNKPGQVRQEK*GRIHL*GDRQG*KTKKEK SIKGRKEII*LGLKGKVFAIRHVLLVPVSILGP RMEKKISYW*YNNVLSLESVFLKS*LLVFTCLI LKEKGAEAIPCRSKDKRIGKDSKL**SHSFPRYK T*N*EVQ*AEVENDLVPDSYPQSK*FINLKSKL LS*YHFGLHFSQDRKYVPP*LSCFKN*NPASQD HSTSNFAQTSPHPSACLELTQGHQTTWL*TNCLN LLGEGD*LD*ETRSEWERVRTSQCWPVRA*LEA KTVAAKEDLAQEKPVGCANFCPENRVDRSLWGT WRNWDLVMLLFSDCEFW*CKTEYSVNLMSV*IMS VNTVKYSIRSQ