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Sequences

Sequence NM_001017977

GTTGCTGATCTTTGGATGTTCTGGTTAGTCTAAGAAGGAGAGTATGAGGCGAGCTCCGGCCCGGGTGCGGCCGGGCTTCAGGGGCCCAGGCGCCGCTGCT
GCCACCGCCATCTAACGCTGCGCCCTGGAGGCCCGGCGCGCGGATGGTGCCGGTGCGGCTCGGGTGTTGAAACGGGTGTCCCCTCCCCCTCCTCCCCTCC
CCCACGCGGTGGTCTCCCCTCCCACCCGGCTCAGGCAGAGCCATGTCTCGGGGTGGCTCCTACCCACACCTGTTGTGGGACGTGAGGAAAAGGTCCCTCG
GGCTGGAGGACCCGTCCCGGCTGCGGAGTCGATACCTGGGAAGAAGAGAATTTATCCAAAGATTAAAACTTGAAGCAACCCTTAATGTGCATGATGGTTG
TGTTAATACAATCTGTTGGAATGACACTGGAGAATATATTTTATCTGGCTCAGATGACACCAAATTAGTAATTAGTAATCCTTACAGCAGAAAGGTTTTG
ACAACAATTCGTTCAGGGCACCGAGCAAACATATTTAGTGCAAAGTTCTTACCTTGTACAAATGATAAACAGATTGTATCCTGCTCTGGAGATGGAGTAA
TATTTTATACCAACGTTGAGCAAGATGCAGAAACCAACAGACAATGCCAATTTACGTGTCATTATGGAACTACTTATGAGATTATGACTGTACCCAATGA
CCCTTACACTTTTCTCTCTTGTGGTGAAGATGGAACTGTTAGGTGGTTTGATACACGCATCAAAACTAGCTGCACAAAAGAAGATTGTAAAGATGATATT
TTAATTAACTGTCGACGTGCTGCCACGTCTGTTGCTATTTGCCCACCAATACCATATTACCTTGCTGTTGGTTGTTCTGACAGCTCAGTACGAATATATG
ATCGGCGAATGCTGGGCACAAGAGCTACAGGGAATTATGCAGGTCGAGGGACTACTGGAATGGTTGCCCGTTTTATTCCTTCCCATCTTAATAATAAGTC
CTGCAGAGTGACATCTCTGTGTTACAGTGAAGATGGTCAAGAGATTCTCGTTAGTTACTCTTCAGATTACATATATCTTTTTGACCCGAAAGATGATACA
GCACGAGAACTTAAAACTCCTTCTGCGGAAGAGAGAAGAGAAGAGTTGCGACAACCACCAGTTAAGCGTTTGAGACTTCGTGGTGATTGGTCAGATACTG
GACCCAGAGCAAGGCCGGAGAGTGAACGAGAACGAGATGGAGAGCAGAGTCCCAATGTGTCATTGATGCAGAGAATGTCTGATATGTTATCAAGATGGTT
TGAAGAAGCAAGTGAGGTTGCACAAAGCAATAGAGGACGAGGAAGATCTCGACCCAGAGGTGGAACAAGTCAATCAGATATTTCAACTCTTCCTACGGTC
CCATCAAGTCCTGATTTGGAAGTGAGTGAAACTGCAATGGAAGTAGATACTCCAGCTGAACAATTTCTTCAGCCTTCTACATCCTCTACAATGTCAGCTC
AGGCTCATTCGACATCATCTCCCACAGAAAGCCCTCATTCTACTCCTTTGCTATCTTCTCCAGACAGTGAACAAAGGCAGTCTGTTGAGGCATCTGGACA
CCACACACATCATCAGTCTGATAACAATAATGAAAAGCTGAGCCCCAAACCAGGGACAGGTGAACCAGTTTTAAGTTTGCACTACAGCACAGAAGGAACA
ACTACAAGCACAATAAAACTGAACTTTACAGATGAATGGAGCAGTATAGCATCAAGTTCTAGAGGAATTGGGAGCCATTGCAAATCTGAGGGTCAGGAGG
AATCTTTCGTCCCACAGAGCTCAGTGCAACCACCAGAAGGAGACAGTGAAACAAAAGCTCCTGAAGAATCATCAGAGGATGTGACAAAATATCAGGAAGG
AGTATCTGCAGAAAACCCAGTTGAGAACCATATCAATATAACACAATCAGATAAGTTCACAGCCAAGCCATTGGATTCCAACTCAGGAGAAAGAAATGAC
CTCAATCTTGATCGCTCTTGTGGGGTTCCAGAAGAATCTGCTTCATCTGAAAAAGCCAAGGAACCAGAAACTTCAGATCAGACTAGCACTGAGAGTGCTA
CCAATGAAAATAACACCAATCCTGAGCCTCAGTTCCAAACAGAAGCCACTGGGCCTTCAGCTCATGAAGAAACATCCACCAGGGACTCTGCTCTTCAGGA
CACAGATGACAGTGATGATGACCCAGTCCTGATCCCAGGTGCAAGGTATCGAGCAGGACCTGGTGATAGACGCTCTGCTGTTGCCCGTATTCAGGAGTTC
TTCAGACGGAGAAAAGAAAGGAAAGAAATGGAAGAATTGGATACTTTGAACATTAGAAGGCCGCTAGTAAAAATGGTTTATAAAGGCCATCGCAACTCCA
GGACAATGATAAAAGAAGCCAATTTCTGGGGTGCTAACTTTGTAATGAGTGGTTCTGACTGTGGCCACATTTTCATCTGGGATCGGCACACTGCTGAGCA
TTTGATGCTTCTGGAAGCTGATAATCATGTGGTAAACTGCCTGCAGCCACATCCGTTTGACCCAATTTTAGCCTCATCTGGCATAGATTATGACATAAAG
ATCTGGTCACCATTAGAAGAGTCAAGGATTTTTAACCGAAAACTTGCTGATGAAGTTATAACTCGAAACGAACTCATGCTGGAAGAAACTAGAAACACCA
TTACAGTTCCAGCCTCTTTCATGTTGAGGATGTTGGCTTCACTTAATCATATCCGAGCTGACCGGTTGGAGGGTGACAGATCAGAAGGCTCTGGTCAAGA
GAATGAAAATGAGGATGAGGAATAATAAACTCTTTTTGGCAAGCACTTAAATGTTCTGAAATTTGTATAAGACATTTATTATATTTTTTTCTTTACAGAG
CTTTAGTGCAATTTTAAGGTTATGGTTTTTGGAGTTTTTCCCTTTTTTTGGGATAACCTAACATTGGTTTGGAATGATTGTGTGCATGAATTTGGGAGAT
TGTATAAAACAAAACTAGCAGAATGTTTTTAAAACTTTTTGCCGTGTATGAGGAGTGCTAGAAAATGCAAAGTGCAATATTTTCCCTAACCTTCAAATGT
GGGAGCTTGGATCAATGTTGAAGAATAATTTTCATCATAGTGAAAATGTTGGTTCAAATAAATTTCTACACTTGCCATTTGCATGTTTGTTGCTTTCTAA
TTAAAGAAACTGGTTGTTTTAAGATACCCTGAA
  • refseq_IQWD1.F2 (forward primer)
  • refseq_IQWD1.R2 (reverse primer)
  • Single exon skipping

Frame 0

VADLWMFWLV*EGEYEASSGPGAAGLQGPRRRC
CHRHLTLRPGGPARGWCRCGSGVETGVPSPSSPP
PRGGLPSHPAQAEPCLGVAPTHTCCGT*GKGPS
GWRTRPGCGVDTWEEENLSKD*NLKQPLMCMMV
VLIQSVGMTLENIFYLAQMTPN**LVILTAERF*
QQFVQGTEQTYLVQSSYLVQMINRLYPALEME*
YFIPTLSKMQKPTDNANLRVIMELLMRL*LYPM
TLTLFSLVVKMELLGGLIHASKLAAQKKIVKMIF
*LTVDVLPRLLLFAHQYHITLLLVVLTAQYEYM
IGECWAQELQGIMQVEGLLEWLPVLFLPILIIS
PAE*HLCVTVKMVKRFSLVTLQITYIFLTRKMIQ
HENLKLLLRKREEKSCDNHQLSV*DFVVIGQIL
DPEQGRRVNENEMESRVPMCH*CRECLICYQDG
LKKQVRLHKAIEDEEDLDPEVEQVNQIFQLFLRS
HQVLIWK*VKLQWK*ILQLNNFFSLLHPLQCQL
RLIRHHLPQKALILLLCYLLQTVNKGSLLRHLD
TTHIISLITIMKS*APNQGQVNQF*VCTTAQKEQ
LQAQ*N*TLQMNGAV*HQVLEELGAIANLRVRR
NLSSHRAQCNHQKETVKQKLLKNHQRM*QNIRK
EYLQKTQLRTISI*HNQISSQPSHWIPTQEKEMT
SILIALVGFQKNLLHLKKPRNQKLQIRLALRVL
PMKITPILSLSSKQKPLGLQLMKKHPPGTLLFR
TQMTVMMTQS*SQVQGIEQDLVIDALLLPVFRSS
SDGEKKGKKWKNWIL*TLEGR**KWFIKAIATP
GQ**KKPISGVLTL**VVLTVATFSSGIGTLLS
I*CFWKLIIMW*TACSHIRLTQF*PHLA*IMT*R
SGHH*KSQGFLTENLLMKL*LETNSCWKKLETP
LQFQPLSC*GCWLHLIISELTGWRVTDQKALVK
RMKMRMRNNKLFLAST*MF*NLYKTFIIFFSLQS
FSAILRLWFLEFFPFFGIT*HWFGMIVCMNLGD
CIKQN*QNVFKTFCRV*GVLENAKCNIFPNLQM
WELGSMLKNNFHHSENVGSNKFLHLPFACLLLSN
*RNWLF*DTL

Frame 1

LLIFGCSG*SKKESMRRAPARVRPGFRGPGAAA
ATAI*RCALEARRADGAGAARVLKRVSPPPPPL
PHAVVSPPTRLRQSHVSGWLLPTPVVGREEKVPR
AGGPVPAAESIPGKKRIYPKIKT*SNP*CA*WL
C*YNLLE*HWRIYFIWLR*HQISN**SLQQKGF
DNNSFRAPSKHI*CKVLTLYK**TDCILLWRWSN
ILYQR*ARCRNQQTMPIYVSLWNYL*DYDCTQ*
PLHFSLLW*RWNC*VV*YTHQN*LHKRRL*R*Y
FN*LSTCCHVCCYLPTNTILPCCWLF*QLSTNI*
SANAGHKSYRELCRSRDYWNGCPFYSFPS***V
LQSDISVLQ*RWSRDSR*LLFRLHISF*PER*Y
STRT*NSFCGREKRRVATTTS*AFETSW*LVRYW
TQSKAGE*TRTRWRAESQCVIDAENV*YVIKMV
*RSK*GCTKQ*RTRKISTQRWNKSIRYFNSSYG
PIKS*FGSE*NCNGSRYSS*TISSAFYILYNVSS
GSFDIISHRKPSFYSFAIFSRQ*TKAVC*GIWT
PHTSSV**Q**KAEPQTRDR*TSFKFALQHRRN
NYKHNKTELYR*MEQYSIKF*RNWEPLQI*GSGG
IFRPTELSATTRRRQ*NKSS*RIIRGCDKISGR
SICRKPS*EPYQYNTIR*VHSQAIGFQLRRKK*
PQS*SLLWGSRRICFI*KSQGTRNFRSD*H*ECY
Q*K*HQS*ASVPNRSHWAFSS*RNIHQGLCSSG
HR*Q***PSPDPRCKVSSRTW**TLCCCPYSGV
LQTEKRKERNGRIGYFEH*KAASKNGL*RPSQLQ
DNDKRSQFLGC*LCNEWF*LWPHFHLGSAHC*A
FDASGS**SCGKLPAATSV*PNFSLIWHRL*HK
DLVTIRRVKDF*PKTC**SYNSKRTHAGRN*KHH
YSSSLFHVEDVGFT*SYPS*PVGG*QIRRLWSR
E*K*G*GIINSFWQALKCSEICIRHLLYFFLYR
ALVQF*GYGFWSFSLFLG*PNIGLE*LCA*IWEI
V*NKTSRMFLKLFAVYEEC*KMQSAIFSLTFKC
GSLDQC*RIIFIIVKMLVQINFYTCHLHVCCFL
IKETGCFKIP*

Frame 2

C*SLDVLVSLRRRV*GELRPGCGRASGAQAPLL
PPPSNAAPWRPGARMVPVRLGC*NGCPLPLLPS
PTRWSPLPPGSGRAMSRGGSYPHLLWDVRKRSL
GLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGC
VNTICWNDTGEYILSGSDDTKLVISNPYSRKVL
TTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGV
IFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPND
PYTFLSCGEDGTVRWFDTRIKTSCTKEDCKDDI
LINCRRAATSVAICPPIPYYLAVGCSDSSVRIY
DRRMLGTRATGNYAGRGTTGMVARFIPSHLNNKS
CRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDT
ARELKTPSAEERREELRQPPVKRLRLRGDWSDT
GPRARPESERERDGEQSPNVSLMQRMSDMLSRWF
EEASEVAQSNRGRGRSRPRGGTSQSDISTLPTV
PSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSA
QAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGH
HTHHQSDNNNEKLSPKPGTGEPVLSLHYSTEGT
TTSTIKLNFTDEWSSIASSSRGIGSHCKSEGQE
ESFVPQSSVQPPEGDSETKAPEESSEDVTKYQEG
VSAENPVENHINITQSDKFTAKPLDSNSGERND
LNLDRSCGVPEESASSEKAKEPETSDQTSTESA
TNENNTNPEPQFQTEATGPSAHEETSTRDSALQD
TDDSDDDPVLIPGARYRAGPGDRRSAVARIQEF
FRRRKERKEMEELDTLNIRRPLVKMVYKGHRNS
RTMIKEANFWGANFVMSGSDCGHIFIWDRHTAEH
LMLLEADNHVVNCLQPHPFDPILASSGIDYDIK
IWSPLEESRIFNRKLADEVITRNELMLEETRNT
ITVPASFMLRMLASLNHIRADRLEGDRSEGSGQE
NENEDEE**TLFGKHLNVLKFV*DIYYIFFFTE
L*CNFKVMVFGVFPFFWDNLTLVWNDCVHEFGR
LYKTKLAECF*NFLPCMRSARKCKVQYFP*PSNV
GAWINVEE*FSS**KCWFK*ISTLAICMFVAF*
LKKLVVLRYPE

Sequence NM_018442

GTTGCTGATCTTTGGATGTTCTGGTTAGTCTAAGAAGGAGAGTATGAGGCGAGCTCCGGCCCGGGTGCGGCCGGGCTTCAGGGGCCCAGGCGCCGCTGCT
GCCACCGCCATCTAACGCTGCGCCCTGGAGGCCCGGCGCGCGGATGGTGCCGGTGCGGCTCGGGTGTTGAAACGGGTGTCCCCTCCCCCTCCTCCCCTCC
CCCACGCGGTGGTCTCCCCTCCCACCCGGCTCAGGCAGAGCCATGTCTCGGGGTGGCTCCTACCCACACCTGTTGTGGGACGTGAGGAAAAGGTCCCTCG
GGCTGGAGGACCCGTCCCGGCTGCGGAGTCGATACCTGGGAAGAAGAGAATTTATCCAAAGATTAAAACTTGAAGCAACCCTTAATGTGCATGATGGTTG
TGTTAATACAATCTGTTGGAATGACACTGGAGAATATATTTTATCTGGCTCAGATGACACCAAATTAGTAATTAGTAATCCTTACAGCAGAAAGGTTTTG
ACAACAATTCGTTCAGGGCACCGAGCAAACATATTTAGTGCAAAGTTCTTACCTTGTACAAATGATAAACAGATTGTATCCTGCTCTGGAGATGGAGTAA
TATTTTATACCAACGTTGAGCAAGATGCAGAAACCAACAGACAATGCCAATTTACGTGTCATTATGGAACTACTTATGAGATTATGACTGTACCCAATGA
CCCTTACACTTTTCTCTCTTGTGGTGAAGATGGAACTGTTAGGTGGTTTGATACACGCATCAAAACTAGCTGCACAAAAGAAGATTGTAAAGATGATATT
TTAATTAACTGTCGACGTGCTGCCACGTCTGTTGCTATTTGCCCACCAATACCATATTACCTTGCTGTTGGTTGTTCTGACAGCTCAGTACGAATATATG
ATCGGCGAATGCTGGGCACAAGAGCTACAGGGAATTATGCAGGTCGAGGGACTACTGGAATGGTTGCCCGTTTTATTCCTTCCCATCTTAATAATAAGTC
CTGCAGAGTGACATCTCTGTGTTACAGTGAAGATGGTCAAGAGATTCTCGTTAGTTACTCTTCAGATTACATATATCTTTTTGACCCGAAAGATGATACA
GCACGAGAACTTAAAACTCCTTCTGCGGAAGAGAGAAGAGAAGAGTTGCGACAACCACCAGTTAAGCGTTTGAGACTTCGTGGTGATTGGTCAGATACTG
GACCCAGAGCAAGGCCGGAGAGTGAACGAGAACGAGATGGAGAGCAGAGTCCCAATGTGTCATTGATGCAGAGAATGTCTGATATGTTATCAAGATGGTT
TGAAGAAGCAAGTGAGGTTGCACAAAGCAATAGAGGACGAGGAAGATCTCGACCCAGAGGTGGAACAAGTCAATCAGATATTTCAACTCTTCCTACGGTC
CCATCAAGTCCTGATTTGGAAGTGAGTGAAACTGCAATGGAAGTAGATACTCCAGCTGAACAATTTCTTCAGCCTTCTACATCCTCTACAATGTCAGCTC
AGGCTCATTCGACATCATCTCCCACAGAAAGCCCTCATTCTACTCCTTTGCTATCTTCTCCAGACAGTGAACAAAGGCAGTCTGTTGAGGCATCTGGACA
CCACACACATCATCAGTCTGATTCTCCTTCTTCTGTGGTTAACAAACAGCTCGGATCCATGTCACTTGACGAGCAACAGGATAACAATAATGAAAAGCTG
AGCCCCAAACCAGGGACAGGTGAACCAGTTTTAAGTTTGCACTACAGCACAGAAGGAACAACTACAAGCACAATAAAACTGAACTTTACAGATGAATGGA
GCAGTATAGCATCAAGTTCTAGAGGAATTGGGAGCCATTGCAAATCTGAGGGTCAGGAGGAATCTTTCGTCCCACAGAGCTCAGTGCAACCACCAGAAGG
AGACAGTGAAACAAAAGCTCCTGAAGAATCATCAGAGGATGTGACAAAATATCAGGAAGGAGTATCTGCAGAAAACCCAGTTGAGAACCATATCAATATA
ACACAATCAGATAAGTTCACAGCCAAGCCATTGGATTCCAACTCAGGAGAAAGAAATGACCTCAATCTTGATCGCTCTTGTGGGGTTCCAGAAGAATCTG
CTTCATCTGAAAAAGCCAAGGAACCAGAAACTTCAGATCAGACTAGCACTGAGAGTGCTACCAATGAAAATAACACCAATCCTGAGCCTCAGTTCCAAAC
AGAAGCCACTGGGCCTTCAGCTCATGAAGAAACATCCACCAGGGACTCTGCTCTTCAGGACACAGATGACAGTGATGATGACCCAGTCCTGATCCCAGGT
GCAAGGTATCGAGCAGGACCTGGTGATAGACGCTCTGCTGTTGCCCGTATTCAGGAGTTCTTCAGACGGAGAAAAGAAAGGAAAGAAATGGAAGAATTGG
ATACTTTGAACATTAGAAGGCCGCTAGTAAAAATGGTTTATAAAGGCCATCGCAACTCCAGGACAATGATAAAAGAAGCCAATTTCTGGGGTGCTAACTT
TGTAATGAGTGGTTCTGACTGTGGCCACATTTTCATCTGGGATCGGCACACTGCTGAGCATTTGATGCTTCTGGAAGCTGATAATCATGTGGTAAACTGC
CTGCAGCCACATCCGTTTGACCCAATTTTAGCCTCATCTGGCATAGATTATGACATAAAGATCTGGTCACCATTAGAAGAGTCAAGGATTTTTAACCGAA
AACTTGCTGATGAAGTTATAACTCGAAACGAACTCATGCTGGAAGAAACTAGAAACACCATTACAGTTCCAGCCTCTTTCATGTTGAGGATGTTGGCTTC
ACTTAATCATATCCGAGCTGACCGGTTGGAGGGTGACAGATCAGAAGGCTCTGGTCAAGAGAATGAAAATGAGGATGAGGAATAATAAACTCTTTTTGGC
AAGCACTTAAATGTTCTGAAATTTGTATAAGACATTTATTATATTTTTTTCTTTACAGAGCTTTAGTGCAATTTTAAGGTTATGGTTTTTGGAGTTTTTC
CCTTTTTTTGGGATAACCTAACATTGGTTTGGAATGATTGTGTGCATGAATTTGGGAGATTGTATAAAACAAAACTAGCAGAATGTTTTTAAAACTTTTT
GCCGTGTATGAGGAGTGCTAGAAAATGCAAAGTGCAATATTTTCCCTAACCTTCAAATGTGGGAGCTTGGATCAATGTTGAAGAATAATTTTCATCATAG
TGAAAATGTTGGTTCAAATAAATTTCTACACTTGCCATTTGCATGTTTGTTGCTTTCTAATTAAAGAAACTGGTTGTTTTAAGATACCCTGAA
  • refseq_IQWD1.F2 (forward primer)
  • refseq_IQWD1.R2 (reverse primer)
  • Single exon skipping

Frame 0

VADLWMFWLV*EGEYEASSGPGAAGLQGPRRRC
CHRHLTLRPGGPARGWCRCGSGVETGVPSPSSPP
PRGGLPSHPAQAEPCLGVAPTHTCCGT*GKGPS
GWRTRPGCGVDTWEEENLSKD*NLKQPLMCMMV
VLIQSVGMTLENIFYLAQMTPN**LVILTAERF*
QQFVQGTEQTYLVQSSYLVQMINRLYPALEME*
YFIPTLSKMQKPTDNANLRVIMELLMRL*LYPM
TLTLFSLVVKMELLGGLIHASKLAAQKKIVKMIF
*LTVDVLPRLLLFAHQYHITLLLVVLTAQYEYM
IGECWAQELQGIMQVEGLLEWLPVLFLPILIIS
PAE*HLCVTVKMVKRFSLVTLQITYIFLTRKMIQ
HENLKLLLRKREEKSCDNHQLSV*DFVVIGQIL
DPEQGRRVNENEMESRVPMCH*CRECLICYQDG
LKKQVRLHKAIEDEEDLDPEVEQVNQIFQLFLRS
HQVLIWK*VKLQWK*ILQLNNFFSLLHPLQCQL
RLIRHHLPQKALILLLCYLLQTVNKGSLLRHLD
TTHIISLILLLLWLTNSSDPCHLTSNRITIMKS*
APNQGQVNQF*VCTTAQKEQLQAQ*N*TLQMNG
AV*HQVLEELGAIANLRVRRNLSSHRAQCNHQK
ETVKQKLLKNHQRM*QNIRKEYLQKTQLRTISI*
HNQISSQPSHWIPTQEKEMTSILIALVGFQKNL
LHLKKPRNQKLQIRLALRVLPMKITPILSLSSK
QKPLGLQLMKKHPPGTLLFRTQMTVMMTQS*SQV
QGIEQDLVIDALLLPVFRSSSDGEKKGKKWKNW
IL*TLEGR**KWFIKAIATPGQ**KKPISGVLT
L**VVLTVATFSSGIGTLLSI*CFWKLIIMW*TA
CSHIRLTQF*PHLA*IMT*RSGHH*KSQGFLTE
NLLMKL*LETNSCWKKLETPLQFQPLSC*GCWL
HLIISELTGWRVTDQKALVKRMKMRMRNNKLFLA
ST*MF*NLYKTFIIFFSLQSFSAILRLWFLEFF
PFFGIT*HWFGMIVCMNLGDCIKQN*QNVFKTF
CRV*GVLENAKCNIFPNLQMWELGSMLKNNFHHS
ENVGSNKFLHLPFACLLLSN*RNWLF*DTL

Frame 1

LLIFGCSG*SKKESMRRAPARVRPGFRGPGAAA
ATAI*RCALEARRADGAGAARVLKRVSPPPPPL
PHAVVSPPTRLRQSHVSGWLLPTPVVGREEKVPR
AGGPVPAAESIPGKKRIYPKIKT*SNP*CA*WL
C*YNLLE*HWRIYFIWLR*HQISN**SLQQKGF
DNNSFRAPSKHI*CKVLTLYK**TDCILLWRWSN
ILYQR*ARCRNQQTMPIYVSLWNYL*DYDCTQ*
PLHFSLLW*RWNC*VV*YTHQN*LHKRRL*R*Y
FN*LSTCCHVCCYLPTNTILPCCWLF*QLSTNI*
SANAGHKSYRELCRSRDYWNGCPFYSFPS***V
LQSDISVLQ*RWSRDSR*LLFRLHISF*PER*Y
STRT*NSFCGREKRRVATTTS*AFETSW*LVRYW
TQSKAGE*TRTRWRAESQCVIDAENV*YVIKMV
*RSK*GCTKQ*RTRKISTQRWNKSIRYFNSSYG
PIKS*FGSE*NCNGSRYSS*TISSAFYILYNVSS
GSFDIISHRKPSFYSFAIFSRQ*TKAVC*GIWT
PHTSSV*FSFFCG*QTARIHVT*RATG*Q**KA
EPQTRDR*TSFKFALQHRRNNYKHNKTELYR*ME
QYSIKF*RNWEPLQI*GSGGIFRPTELSATTRR
RQ*NKSS*RIIRGCDKISGRSICRKPS*EPYQY
NTIR*VHSQAIGFQLRRKK*PQS*SLLWGSRRIC
FI*KSQGTRNFRSD*H*ECYQ*K*HQS*ASVPN
RSHWAFSS*RNIHQGLCSSGHR*Q***PSPDPR
CKVSSRTW**TLCCCPYSGVLQTEKRKERNGRIG
YFEH*KAASKNGL*RPSQLQDNDKRSQFLGC*L
CNEWF*LWPHFHLGSAHC*AFDASGS**SCGKL
PAATSV*PNFSLIWHRL*HKDLVTIRRVKDF*PK
TC**SYNSKRTHAGRN*KHHYSSSLFHVEDVGF
T*SYPS*PVGG*QIRRLWSRE*K*G*GIINSFW
QALKCSEICIRHLLYFFLYRALVQF*GYGFWSFS
LFLG*PNIGLE*LCA*IWEIV*NKTSRMFLKLF
AVYEEC*KMQSAIFSLTFKCGSLDQC*RIIFII
VKMLVQINFYTCHLHVCCFLIKETGCFKIP*

Frame 2

C*SLDVLVSLRRRV*GELRPGCGRASGAQAPLL
PPPSNAAPWRPGARMVPVRLGC*NGCPLPLLPS
PTRWSPLPPGSGRAMSRGGSYPHLLWDVRKRSL
GLEDPSRLRSRYLGRREFIQRLKLEATLNVHDGC
VNTICWNDTGEYILSGSDDTKLVISNPYSRKVL
TTIRSGHRANIFSAKFLPCTNDKQIVSCSGDGV
IFYTNVEQDAETNRQCQFTCHYGTTYEIMTVPND
PYTFLSCGEDGTVRWFDTRIKTSCTKEDCKDDI
LINCRRAATSVAICPPIPYYLAVGCSDSSVRIY
DRRMLGTRATGNYAGRGTTGMVARFIPSHLNNKS
CRVTSLCYSEDGQEILVSYSSDYIYLFDPKDDT
ARELKTPSAEERREELRQPPVKRLRLRGDWSDT
GPRARPESERERDGEQSPNVSLMQRMSDMLSRWF
EEASEVAQSNRGRGRSRPRGGTSQSDISTLPTV
PSSPDLEVSETAMEVDTPAEQFLQPSTSSTMSA
QAHSTSSPTESPHSTPLLSSPDSEQRQSVEASGH
HTHHQSDSPSSVVNKQLGSMSLDEQQDNNNEKL
SPKPGTGEPVLSLHYSTEGTTTSTIKLNFTDEW
SSIASSSRGIGSHCKSEGQEESFVPQSSVQPPEG
DSETKAPEESSEDVTKYQEGVSAENPVENHINI
TQSDKFTAKPLDSNSGERNDLNLDRSCGVPEES
ASSEKAKEPETSDQTSTESATNENNTNPEPQFQT
EATGPSAHEETSTRDSALQDTDDSDDDPVLIPG
ARYRAGPGDRRSAVARIQEFFRRRKERKEMEEL
DTLNIRRPLVKMVYKGHRNSRTMIKEANFWGANF
VMSGSDCGHIFIWDRHTAEHLMLLEADNHVVNC
LQPHPFDPILASSGIDYDIKIWSPLEESRIFNR
KLADEVITRNELMLEETRNTITVPASFMLRMLAS
LNHIRADRLEGDRSEGSGQENENEDEE**TLFG
KHLNVLKFV*DIYYIFFFTEL*CNFKVMVFGVF
PFFWDNLTLVWNDCVHEFGRLYKTKLAECF*NFL
PCMRSARKCKVQYFP*PSNVGAWINVEE*FSS*
*KCWFK*ISTLAICMFVAF*LKKLVVLRYPE

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