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Sequence NM_016527
TTCTTTAGCCTGAACTGTGGGTAGTGATGTGGTGTGTTTCCTAACACCTCCGGCAGTGAGCCAGGCTTTGAGTGGCTGCGTCTAAACACTTCTTTCCCTGAGGACTGGAAGACATTAGAATAAGGTCCAGAAATGTCCTTGGTGTGTTTGACAGACTTTCAGGCCCATGCGCGAGAGCAGCTGTCTAAGTCAACTCGGGA
TTTTATTGAAGGTGGAGCAGATGACAGCATCACGCGGGATGACAACATTGCAGCATTTAAAAGAATTCGCCTCCGTCCGCGGTACCTGAGAGATGTGTCT
GAGGTGGACACCAGAACCACAATCCAAGGGGAGGAGATCAGTGCCCCTATTTGTATCGCACCCACAGGGTTCCACTGCCTTGTCTGGCCTGATGGGGAAA
TGAGCACAGCAAGAGCTGCCCAAGCGGCTGGTATCTGCTACATCACCAGCACATTTGCCAGCTGTAGCCTTGAAGACATTGTCATTGCAGCTCCCGAAGG
CCTCCGATGGTTCCAACTCTATGTGCATCCAGACCTGCAGCTGAACAAACAGTTGATCCAGAGGGTAGAATCCCTAGGTTTCAAAGCTTTGGTAATAACT
TTGGATACACCTGTATGTGGCAACAGGCGACATGACATTCGAAACCAGTTGAGGAGGAACTTAACACTAACAGATCTTCAATCACCTAAAAAGGGAAATG
CAATACCTTATTTCCAGATGACTCCTATCAGCACTTCTCTCTGCTGGAATGATCTCTCCTGGTTTCAGAGCATAACTCGATTGCCCATCATCCTGAAAGG
GATTTTGACAAAAGAGGATGCAGAGTTAGCTGTGAAGCACAATGTCCAGGGTATCATTGTTTCCAACCATGGTGGGAGGCAGCTTGATGAGGTTCTTGCT
TCAATTGATGCTTTGACAGAAGTGGTGGCTGCTGTAAAGGGGAAAATTGAAGTCTACCTGGATGGCGGGGTCCGAACTGGCAATGATGTGCTGAAGGCTC
TGGCCCTTGGAGCTAAGTGCATTTTTCTTGGGAGACCAATCCTATGGGGCCTTGCCTGCAAGGGTGAACATGGTGTTAAGGAAGTTTTGAACATTTTAAC
AAATGAGTTCCACACTTCCATGGCCCTTACAGGCTGCCGGTCGGTCGCTGAGATCAATCGAAACTTGGTCCAGTTTTCCAGGCTGTAAGAAAAAAGGGCC
AATAACCAGACTGCTGAGGTTGCCCACAGGAGGATCACAAACTCACAGCACAGTGTGTGATGCTGTCCTTCCTGGACCCCATTCTGTCCGGAGGCTCATG
GCCCATATTTCCCACATTTCTAATACCACCACCCCTGTGCTTCAGGCCCTCCAAACCCCTGTGTTCCCCAAATGTTCCATGCCCTTCTTTGTATCACTGA
CTATTATATGTTGCTCTCTTGCCTAAATCTTCCTCTGAAGTAAAAGATCTCAAAAGGACAGATCATTAATGACTGG
- refseq_HAO2.F1 (forward primer)
- refseq_HAO2.R1 (reverse primer)
- Single exon skipping
Frame 0
FFSLNCG**CGVFPNTSGSEPGFEWLRLNTSFPEDWKTLE*GPEMSLVCLTDFQAHAREQLSKSTRD
FIEGGADDSITRDDNIAAFKRIRLRPRYLRDVS
EVDTRTTIQGEEISAPICIAPTGFHCLVWPDGE
MSTARAAQAAGICYITSTFASCSLEDIVIAAPEG
LRWFQLYVHPDLQLNKQLIQRVESLGFKALVIT
LDTPVCGNRRHDIRNQLRRNLTLTDLQSPKKGN
AIPYFQMTPISTSLCWNDLSWFQSITRLPIILKG
ILTKEDAELAVKHNVQGIIVSNHGGRQLDEVLA
SIDALTEVVAAVKGKIEVYLDGGVRTGNDVLKA
LALGAKCIFLGRPILWGLACKGEHGVKEVLNILT
NEFHTSMALTGCRSVAEINRNLVQFSRL*EKRA
NNQTAEVAHRRITNSQHSV*CCPSWTPFCPEAH
GPYFPHF*YHHPCASGPPNPCVPQMFHALLCITD
YYMLLSCLNLPLK*KISKGQIINDW
Frame 1
SLA*TVGSDVVCFLTPPAVSQALSGCV*TLLSLRTGRH*NKVQKCPWCV*QTFRPMRESSCLSQLG
ILLKVEQMTASRGMTTLQHLKEFASVRGT*EMCL
RWTPEPQSKGRRSVPLFVSHPQGSTALSGLMGK
*AQQELPKRLVSATSPAHLPAVALKTLSLQLPK
ASDGSNSMCIQTCS*TNS*SRG*NP*VSKLW**L
WIHLYVATGDMTFETS*GGT*H*QIFNHLKREM
QYLISR*LLSALLSAGMISPGFRA*LDCPSS*K
GF*QKRMQS*L*STMSRVSLFPTMVGGSLMRFLL
QLML*QKWWLL*RGKLKSTWMAGSELAMMC*RL
WPLELSAFFLGDQSYGALPARVNMVLRKF*TF*
QMSSTLPWPLQAAGRSLRSIETWSSFPGCKKKGP
ITRLLRLPTGGSQTHSTVCDAVLPGPHSVRRLM
AHISHISNTTTPVLQALQTPVFPKCSMPFFVSL
TIICCSLA*IFL*SKRSQKDRSLMT
Frame 2
L*PELWVVMWCVS*HLRQ*ARL*VAASKHFFP*GLEDIRIRSRNVLGVFDRLSGPCARAAV*VNSG
FY*RWSR*QHHAG*QHCSI*KNSPPSAVPERCV
*GGHQNHNPRGGDQCPYLYRTHRVPLPCLA*WGN
EHSKSCPSGWYLLHHQHICQL*P*RHCHCSSRR
PPMVPTLCASRPAAEQTVDPEGRIPRFQSFGNN
FGYTCMWQQAT*HSKPVEEELNTNRSSIT*KGKC
NTLFPDDSYQHFSLLE*SLLVSEHNSIAHHPER
DFDKRGCRVSCEAQCPGYHCFQPWWEAA**GSC
FN*CFDRSGGCCKGEN*SLPGWRGPNWQ*CAEGS
GPWS*VHFSWETNPMGPCLQG*TWC*GSFEHFN
K*VPHFHGPYRLPVGR*DQSKLGPVFQAVRKKG
Q*PDC*GCPQEDHKLTAQCVMLSFLDPILSGGSW
PIFPTFLIPPPLCFRPSKPLCSPNVPCPSLYH*
LLYVALLPKSSSEVKDLKRTDH**L
Sequence NM_001005783
TTCTTTAGCCTGAACTGTGGGTAGTGATGTGGTGTGTTTCCTAACACCTCCGGCAGTGAGCCAGGCTTTGAGTGGCTGCGTCTAAACACTTCTTTCCCTGAGGACTGGAAGACATTAGAATAAGCTCCAGACAATTCAAACATTGAGATTCCTGGGAACTACCAGATAGTAGCATCAGTTCACCAAGAAATGAAGCTGGT
GAGGCAGTGAAAATCCAGGGCCTAGAAAGCTGGGAATGCCATGACGTGGGCACATTGAAAGACAAGAGGCAGGCATGATCAGCCTTGAACTTTAGGAAGA
TCCCAGGAAGCTGATGGAAGACAAGATGTGGAGTGAATGTGAAGGTCCAGAAATGTCCTTGGTGTGTTTGACAGACTTTCAGGCCCATGCGCGAGAGCAG
CTGTCTAAGTCAACTCGGGATTTTATTGAAGGTGGAGCAGATGACAGCATCACGCGGGATGACAACATTGCAGCATTTAAAAGAATTCGCCTCCGTCCGC
GGTACCTGAGAGATGTGTCTGAGGTGGACACCAGAACCACAATCCAAGGGGAGGAGATCAGTGCCCCTATTTGTATCGCACCCACAGGGTTCCACTGCCT
TGTCTGGCCTGATGGGGAAATGAGCACAGCAAGAGCTGCCCAAGCGGCTGGTATCTGCTACATCACCAGCACATTTGCCAGCTGTAGCCTTGAAGACATT
GTCATTGCAGCTCCCGAAGGCCTCCGATGGTTCCAACTCTATGTGCATCCAGACCTGCAGCTGAACAAACAGTTGATCCAGAGGGTAGAATCCCTAGGTT
TCAAAGCTTTGGTAATAACTTTGGATACACCTGTATGTGGCAACAGGCGACATGACATTCGAAACCAGTTGAGGAGGAACTTAACACTAACAGATCTTCA
ATCACCTAAAAAGGGAAATGCAATACCTTATTTCCAGATGACTCCTATCAGCACTTCTCTCTGCTGGAATGATCTCTCCTGGTTTCAGAGCATAACTCGA
TTGCCCATCATCCTGAAAGGGATTTTGACAAAAGAGGATGCAGAGTTAGCTGTGAAGCACAATGTCCAGGGTATCATTGTTTCCAACCATGGTGGGAGGC
AGCTTGATGAGGTTCTTGCTTCAATTGATGCTTTGACAGAAGTGGTGGCTGCTGTAAAGGGGAAAATTGAAGTCTACCTGGATGGCGGGGTCCGAACTGG
CAATGATGTGCTGAAGGCTCTGGCCCTTGGAGCTAAGTGCATTTTTCTTGGGAGACCAATCCTATGGGGCCTTGCCTGCAAGGGTGAACATGGTGTTAAG
GAAGTTTTGAACATTTTAACAAATGAGTTCCACACTTCCATGGCCCTTACAGGCTGCCGGTCGGTCGCTGAGATCAATCGAAACTTGGTCCAGTTTTCCA
GGCTGTAAGAAAAAAGGGCCAATAACCAGACTGCTGAGGTTGCCCACAGGAGGATCACAAACTCACAGCACAGTGTGTGATGCTGTCCTTCCTGGACCCC
ATTCTGTCCGGAGGCTCATGGCCCATATTTCCCACATTTCTAATACCACCACCCCTGTGCTTCAGGCCCTCCAAACCCCTGTGTTCCCCAAATGTTCCAT
GCCCTTCTTTGTATCACTGACTATTATATGTTGCTCTCTTGCCTAAATCTTCCTCTGAAGTAAAAGATCTCAAAAGGACAGATCATTAATGACTGG
- refseq_HAO2.F1 (forward primer)
- refseq_HAO2.R1 (reverse primer)
- Single exon skipping
Frame 0
FFSLNCG**CGVFPNTSGSEPGFEWLRLNTSFPEDWKTLE*APDNSNIEIPGNYQIVASVHQEMKLV
RQ*KSRA*KAGNAMTWAH*KTRGRHDQP*TLGR
SQEADGRQDVE*M*RSRNVLGVFDRLSGPCARA
AV*VNSGFY*RWSR*QHHAG*QHCSI*KNSPPSA
VPERCV*GGHQNHNPRGGDQCPYLYRTHRVPLP
CLA*WGNEHSKSCPSGWYLLHHQHICQL*P*RH
CHCSSRRPPMVPTLCASRPAAEQTVDPEGRIPRF
QSFGNNFGYTCMWQQAT*HSKPVEEELNTNRSS
IT*KGKCNTLFPDDSYQHFSLLE*SLLVSEHNS
IAHHPERDFDKRGCRVSCEAQCPGYHCFQPWWEA
A**GSCFN*CFDRSGGCCKGEN*SLPGWRGPNW
Q*CAEGSGPWS*VHFSWETNPMGPCLQG*TWC*
GSFEHFNK*VPHFHGPYRLPVGR*DQSKLGPVFQ
AVRKKGQ*PDC*GCPQEDHKLTAQCVMLSFLDP
ILSGGSWPIFPTFLIPPPLCFRPSKPLCSPNVP
CPSLYH*LLYVALLPKSSSEVKDLKRTDH**L
Frame 1
SLA*TVGSDVVCFLTPPAVSQALSGCV*TLLSLRTGRH*NKLQTIQTLRFLGTTR**HQFTKK*SW
*GSENPGPRKLGMP*RGHIERQEAGMISLEL*ED
PRKLMEDKMWSECEGPEMSLVCLTDFQAHAREQ
LSKSTRDFIEGGADDSITRDDNIAAFKRIRLRP
RYLRDVSEVDTRTTIQGEEISAPICIAPTGFHCL
VWPDGEMSTARAAQAAGICYITSTFASCSLEDI
VIAAPEGLRWFQLYVHPDLQLNKQLIQRVESLG
FKALVITLDTPVCGNRRHDIRNQLRRNLTLTDLQ
SPKKGNAIPYFQMTPISTSLCWNDLSWFQSITR
LPIILKGILTKEDAELAVKHNVQGIIVSNHGGR
QLDEVLASIDALTEVVAAVKGKIEVYLDGGVRTG
NDVLKALALGAKCIFLGRPILWGLACKGEHGVK
EVLNILTNEFHTSMALTGCRSVAEINRNLVQFS
RL*EKRANNQTAEVAHRRITNSQHSV*CCPSWTP
FCPEAHGPYFPHF*YHHPCASGPPNPCVPQMFH
ALLCITDYYMLLSCLNLPLK*KISKGQIINDW
Frame 2
L*PELWVVMWCVS*HLRQ*ARL*VAASKHFFP*GLEDIRISSRQFKH*DSWELPDSSISSPRNEAG
EAVKIQGLESWECHDVGTLKDKRQA*SALNFRK
IPGS*WKTRCGVNVKVQKCPWCV*QTFRPMRESS
CLSQLGILLKVEQMTASRGMTTLQHLKEFASVR
GT*EMCLRWTPEPQSKGRRSVPLFVSHPQGSTA
LSGLMGK*AQQELPKRLVSATSPAHLPAVALKTL
SLQLPKASDGSNSMCIQTCS*TNS*SRG*NP*V
SKLW**LWIHLYVATGDMTFETS*GGT*H*QIF
NHLKREMQYLISR*LLSALLSAGMISPGFRA*LD
CPSS*KGF*QKRMQS*L*STMSRVSLFPTMVGG
SLMRFLLQLML*QKWWLL*RGKLKSTWMAGSEL
AMMC*RLWPLELSAFFLGDQSYGALPARVNMVLR
KF*TF*QMSSTLPWPLQAAGRSLRSIETWSSFP
GCKKKGPITRLLRLPTGGSQTHSTVCDAVLPGP
HSVRRLMAHISHISNTTTPVLQALQTPVFPKCSM
PFFVSLTIICCSLA*IFL*SKRSQKDRSLMT
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