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Sequences

Sequence NM_175767

GAGCAGCCAAAAGGCCCGCGGAGTCGCGCTGGGCCGCCCCGGCGCAGCTGAACCGGGGGCCGCGCCTGCCAGGCCGACGGGTCTGGCCCAGCCTGGCGCC
AAGGGGTTCGTGCGCTGTGGAGACGCGGAGGGTCGAGGCGGCGCGGCCTGAGTGAAACCCAATGGAAAAAGCATGACATTTAGAAGTAGAAGACTTAGCT
TCAAATCCCTACTCCTTCACTTACTAATTTTGTGATTTGGAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTC
CTCACCACTGAATCTACAGGTGAACTTCTAGATCCATGTGGTTATATCAGTCCTGAATCTCCAGTTGTACAACTTCATTCTAATTTCACTGCAGTTTGTG
TGCTAAAGGAAAAATGTATGGATTATTTTCATGTAAATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAAGGAGCAATATACTATCAT
AAACAGAACAGCATCCAGTGTCACCTTTACAGATATAGCTTCATTAAATATTCAGCTCACTTGCAACATTCTTACATTCGGACAGCTTGAACAGAATGTT
TATGGAATCACAATAATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGTGAACGAGGGGAAGAAAATGAGGTGTGAGTGGGATGGTG
GAAGGGAAACACACTTGGAGACAAACTTCACTTTAAAATCTGAATGGGCAACACACAAGTTTGCTGATTGCAAAGCAAAACGTGACACCCCCACCTCATG
CACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGTCTGGGTAGAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGATCATATCAATTTTGAT
CCTGTATATAAAGTGAAGCCCAATCCGCCACATAATTTATCAGTGATCAACTCAGAGGAACTGTCTAGTATCTTAAAATTGACATGGACCAACCCAAGTA
TTAAGAGTGTTATAATACTAAAATATAACATTCAATATAGGACCAAAGATGCCTCAACTTGGAGCCAGATTCCTCCTGAAGACACAGCATCCACCCGATC
TTCATTCACTGTCCAAGACCTTAAACCTTTTACAGAATATGTGTTTAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAA
GAAGCAAGTGGGATCACCTATGAAGATAACATTGCCTCCTTTTGAAGCCAATGGAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACAT
TTACAAAATTACACAGTTAATGCCACAAAACTGACAGTAAATCTCACAAATGATCGCTATCTAGCAACCCTAACAGTAAGAAATCTTGTTGGCAAATCAG
ATGCAGCTGTTTTAACTATCCCTGCCTGTGACTTTCAAGCTACTCACCCTGTAATGGATCTTAAAGCATTCCCCAAAGATAACATGCTTTGGGTGGAATG
GACTACTCCAAGGGAATCTGTAAAGAAATATATACTTGAGTGGTGTGTGTTATCAGATAAAGCACCCTGTATCACAGACTGGCAACAAGAAGATGGTACC
GTGCATCGCACCTATTTAAGAGGGAACTTAGCAGAGAGCAAATGCTATTTGATAACAGTTACTCCAGTATATGCTGATGGACCAGGAAGCCCTGAATCCA
TAAAGGCATACCTTAAACAAGCTCCACCTTCCAAAGGACCTACTGTTCGGACAAAAAAAGTAGGGAAAAACGAAGCTGTCTTAGAGTGGGACCAACTTCC
TGTTGATGTTCAGAATGGATTTATCAGAAATTATACTATATTTTATAGAACCATCATTGGAAATGAAACTGCTGTGAATGTGGATTCTTCCCACACAGAA
TATACATTGTCCTCTTTGACTAGTGACACATTGTACATGGTACGAATGGCAGCATACACAGATGAAGGTGGGAAGGATGGTCCAGAATTCACTTTTACTA
CCCCAAAGTTTGCTCAAGGAGAAATTGAAGCCATAGTCGTGCCTGTTTGCTTAGCATTCCTATTGACAACTCTTCTGGGAGTGCTGTTCTGCTTTAATAA
GCGAGACCTAATTAAAAAACACATCTGGCCTAATGTTCCAGATCCTTCAAAGAGTCATATTGCCCAGTGGTCACCTCACACTCCTCCAAGGCACAATTTT
AATTCAAAAGATCAAATGTATTCAGATGGCAATTTCACTGATGTAAGTGTTGTGGAAATAGAAGCAAATGACAAAAAGCCTTTTCCAGAAGATCTGAAAT
CATTGGACCTGTTCAAAAAGGAAAAAATTAATACTGAAGGACACAGCAGTGGTATTGGGGGGTCTTCATGCATGTCATCTTCTAGGCCAAGCATTTCTAG
CAGTGATGAAAATGAATCTTCACAAAACACTTCGAGCACTGTCCAGTATTCTACCGTGGTACACAGTGGCTACAGACACCAAGTTCCGTCAGTCCAAGTC
TTCTCAAGATCCGAGTCTACCCAGCCCTTGTTAGATTCAGAGGAGCGGCCAGAAGATCTACAATTAGTAGATCATGTAGATGGCGGTGATGGTATTTTGC
CCAGGCAACAGTACTTCAAACAGAACTGCAGTCAGCATGAATCCAGTCCAGATATTTCACATTTTGAAAGGTCAAAGCAAGTTTCATCAGTCAATGAGGA
AGATTTTGTTAGACTTAAACAGCAGATTTCAGATCATATTTCACAATCCTGTGGATCTGGGCAAATGAAAATGTTTCAGGAAGTTTCTGCAGCAGATGCT
TTTGGTCCAGGTACTGAGGGACAAGTAGAAAGATTTGAAACAGTTGGCATGGAGGCTGCGACTGATGAAGGCATGCCTAAAAGTTACTTACCACAGACTG
TACGGCAAGGCGGCTACATGCCTCAGTGAAGGACTAGTAGTTCCTGCTACAACTTCAGCAGTACCTATAAAGTAAAGCTAAAATGATTTTATCTGTGAAT
TCAGATTTTAAAAAGTCTTCACTCTCTGAAGATGATCATTTGCCCTTAAGGACAAAAATGAACTGAAGTTTCACATGAGCTATTTCCATTCCAGAATATC
TGGGATTCTACTTTAAGCACTACATAAACTGACTTTATCCTCAGA
  • refseq_IL6ST.F1 (forward primer)
  • refseq_IL6ST.R1 (reverse primer)
  • Single exon skipping

Frame 0

EQPKGPRSRAGPPRRS*TGGRACQADGSGPAWR
QGVRALWRRGGSRRRGLSETQWKKHDI*K*KT*L
QIPTPSLTNFVIWKYPRKMLTLQTWLVQALFIF
LTTESTGELLDPCGYISPESPVVQLHSNFTAVC
VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII
NRTASSVTFTDIASLNIQLTCNILTFGQLEQNV
YGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG
GRETHLETNFTLKSEWATHKFADCKAKRDTPTSC
TVDYSTVYFVNIEVWVEAENALGKVTSDHINFD
PVYKVKPNPPHNLSVINSEELSSILKLTWTNPS
IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS
SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE
EASGITYEDNIASF*SQWKNLGL*SDSHKMEIT
FTKLHS*CHKTDSKSHK*SLSSNPNSKKSCWQIR
CSCFNYPCL*LSSYSPCNGS*SIPQR*HALGGM
DYSKGICKEIYT*VVCVIR*STLYHRLATRRWY
RASHLFKRELSREQMLFDNSYSSIC*WTRKP*IH
KGIP*TSSTFQRTYCSDKKSREKRSCLRVGPTS
C*CSEWIYQKLYYIL*NHHWK*NCCECGFFPHR
IYIVLFD**HIVHGTNGSIHR*RWEGWSRIHFYY
PKVCSRRN*SHSRACLLSIPIDNSSGSAVLL**
ARPN*KTHLA*CSRSFKESYCPVVTSHSSKAQF
*FKRSNVFRWQFH*CKCCGNRSK*QKAFSRRSEI
IGPVQKGKN*Y*RTQQWYWGVFMHVIF*AKHF*
Q**K*IFTKHFEHCPVFYRGTQWLQTPSSVSPS
LLKIRVYPALVRFRGAARRSTISRSCRWR*WYFA
QATVLQTELQSA*IQSRYFTF*KVKASFISQ*G
RFC*T*TADFRSYFTILWIWANENVSGSFCSRC
FWSRY*GTSRKI*NSWHGGCD**RHA*KLLTTDC
TARRLHASVKD**FLLQLQQYL*SKAKMILSVN
SDFKKSSLSEDDHLPLRTKMN*SFT*AISIPEY
LGFYFKHYIN*LYPQ

Frame 1

SSQKARGVALGRPGAAEPGAAPARPTGLAQPGA
KGFVRCGDAEGRGGAA*VKPNGKSMTFRSRRLS
FKSLLLHLLIL*FGNIRARC*RCRLG*CKPCLFS
SPLNLQVNF*IHVVISVLNLQLYNFILISLQFV
C*RKNVWIIFM*MLITLSGKQTILLFLRSNILS
*TEQHPVSPLQI*LH*IFSSLATFLHSDSLNRMF
MESQ*FQACLQKNLKI*VAL*TRGRK*GVSGMV
EGKHTWRQTSL*NLNGQHTSLLIAKQNVTPPPH
ALLIILLCILSTLKSG*KQRMPLGRLHQIISILI
LYIK*SPIRHIIYQ*STQRNCLVS*N*HGPTQV
LRVL*Y*NITFNIGPKMPQLGARFLLKTQHPPD
LHSLSKTLNLLQNMCLGFAV*RKMVRDTGVTGVK
KQVGSPMKITLPPFEANGKILDYEVTLTRWKSH
LQNYTVNATKLTVNLTNDRYLATLTVRNLVGKS
DAAVLTIPACDFQATHPVMDLKAFPKDNMLWVEW
TTPRESVKKYILEWCVLSDKAPCITDWQQEDGT
VHRTYLRGNLAESKCYLITVTPVYADGPGSPES
IKAYLKQAPPSKGPTVRTKKVGKNEAVLEWDQLP
VDVQNGFIRNYTIFYRTIIGNETAVNVDSSHTE
YTLSSLTSDTLYMVRMAAYTDEGGKDGPEFTFT
TPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNK
RDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNF
NSKDQMYSDGNFTDVSVVEIEANDKKPFPEDLK
SLDLFKKEKINTEGHSSGIGGSSCMSSSRPSISS
SDENESSQNTSSTVQYSTVVHSGYRHQVPSVQV
FSRSESTQPLLDSEERPEDLQLVDHVDGGDGIL
PRQQYFKQNCSQHESSPDISHFERSKQVSSVNEE
DFVRLKQQISDHISQSCGSGQMKMFQEVSAADA
FGPGTEGQVERFETVGMEAATDEGMPKSYLPQT
VRQGGYMPQ*RTSSSCYNFSSTYKVKLK*FYL*I
QILKSLHSLKMIICP*GQK*TEVSHELFPFQNI
WDSTLSTT*TDFILR

Frame 2

AAKRPAESRWAAPAQLNRGPRLPGRRVWPSLAP
RGSCAVETRRVEAARPE*NPMEKA*HLEVEDLA
SNPYSFTY*FCDLEISAQDVDVADLASASLVYF
PHH*IYR*TSRSMWLYQS*ISSCTTSF*FHCSLC
AKGKMYGLFSCKC*LHCLENKPFYYS*GAIYYH
KQNSIQCHLYRYSFIKYSAHLQHSYIRTA*TEC
LWNHNNFRLASRKT*KFELHCERGEENEV*VGWW
KGNTLGDKLHFKI*MGNTQVC*LQSKT*HPHLM
HC*LFYCVFCQH*SLGRSRECPWEGYIRSYQF*
SCI*SEAQSAT*FISDQLRGTV*YLKIDMDQPKY
*ECYNTKI*HSI*DQRCLNLEPDSS*RHSIHPI
FIHCPRP*TFYRICV*DSLYEGRW*GILE*LE*
RSKWDHL*R*HCLLLKPMEKSWIMK*LSQDGNHI
YKITQLMPQN*Q*ISQMIAI*QP*Q*EILLANQ
MQLF*LSLPVTFKLLTL*WILKHSPKITCFGWN
GLLQGNL*RNIYLSGVCYQIKHPVSQTGNKKMVP
CIAPI*EGT*QRANAI**QLLQYMLMDQEALNP
*RHTLNKLHLPKDLLFGQKK*GKTKLS*SGTNF
LLMFRMDLSEIILYFIEPSLEMKLL*MWILPTQN
IHCPL*LVTHCTWYEWQHTQMKVGRMVQNSLLL
PQSLLKEKLKP*SCLFA*HSY*QLFWECCSALI
SET*LKNTSGLMFQILQRVILPSGHLTLLQGTIL
IQKIKCIQMAISLM*VLWK*KQMTKSLFQKI*N
HWTCSKRKKLILKDTAVVLGGLHACHLLGQAFL
AVMKMNLHKTLRALSSILPWYTVATDTKFRQSKS
SQDPSLPSPC*IQRSGQKIYN**IM*MAVMVFC
PGNSTSNRTAVSMNPVQIFHILKGQSKFHQSMR
KILLDLNSRFQIIFHNPVDLGK*KCFRKFLQQML
LVQVLRDK*KDLKQLAWRLRLMKACLKVTYHRL
YGKAATCLSEGLVVPATTSAVPIK*S*NDFICE
FRF*KVFTL*R*SFALKDKNELKFHMSYFHSRIS
GILL*ALHKLTLSS

Sequence NM_002184

GAGCAGCCAAAAGGCCCGCGGAGTCGCGCTGGGCCGCCCCGGCGCAGCTGAACCGGGGGCCGCGCCTGCCAGGCCGACGGGTCTGGCCCAGCCTGGCGCC
AAGGGGTTCGTGCGCTGTGGAGACGCGGAGGGTCGAGGCGGCGCGGCCTGAGTGAAACCCAATGGAAAAAGCATGACATTTAGAAGTAGAAGACTTAGCT
TCAAATCCCTACTCCTTCACTTACTAATTTTGTGATTTGGAAATATCCGCGCAAGATGTTGACGTTGCAGACTTGGCTAGTGCAAGCCTTGTTTATTTTC
CTCACCACTGAATCTACAGGTGAACTTCTAGATCCATGTGGTTATATCAGTCCTGAATCTCCAGTTGTACAACTTCATTCTAATTTCACTGCAGTTTGTG
TGCTAAAGGAAAAATGTATGGATTATTTTCATGTAAATGCTAATTACATTGTCTGGAAAACAAACCATTTTACTATTCCTAAGGAGCAATATACTATCAT
AAACAGAACAGCATCCAGTGTCACCTTTACAGATATAGCTTCATTAAATATTCAGCTCACTTGCAACATTCTTACATTCGGACAGCTTGAACAGAATGTT
TATGGAATCACAATAATTTCAGGCTTGCCTCCAGAAAAACCTAAAAATTTGAGTTGCATTGTGAACGAGGGGAAGAAAATGAGGTGTGAGTGGGATGGTG
GAAGGGAAACACACTTGGAGACAAACTTCACTTTAAAATCTGAATGGGCAACACACAAGTTTGCTGATTGCAAAGCAAAACGTGACACCCCCACCTCATG
CACTGTTGATTATTCTACTGTGTATTTTGTCAACATTGAAGTCTGGGTAGAAGCAGAGAATGCCCTTGGGAAGGTTACATCAGATCATATCAATTTTGAT
CCTGTATATAAAGTGAAGCCCAATCCGCCACATAATTTATCAGTGATCAACTCAGAGGAACTGTCTAGTATCTTAAAATTGACATGGACCAACCCAAGTA
TTAAGAGTGTTATAATACTAAAATATAACATTCAATATAGGACCAAAGATGCCTCAACTTGGAGCCAGATTCCTCCTGAAGACACAGCATCCACCCGATC
TTCATTCACTGTCCAAGACCTTAAACCTTTTACAGAATATGTGTTTAGGATTCGCTGTATGAAGGAAGATGGTAAGGGATACTGGAGTGACTGGAGTGAA
GAAGCAAGTGGGATCACCTATGAAGATAGACCATCTAAAGCACCAAGTTTCTGGTATAAAATAGATCCATCCCATACTCAAGGCTACAGAACTGTACAAC
TCGTGTGGAAGACATTGCCTCCTTTTGAAGCCAATGGAAAAATCTTGGATTATGAAGTGACTCTCACAAGATGGAAATCACATTTACAAAATTACACAGT
TAATGCCACAAAACTGACAGTAAATCTCACAAATGATCGCTATCTAGCAACCCTAACAGTAAGAAATCTTGTTGGCAAATCAGATGCAGCTGTTTTAACT
ATCCCTGCCTGTGACTTTCAAGCTACTCACCCTGTAATGGATCTTAAAGCATTCCCCAAAGATAACATGCTTTGGGTGGAATGGACTACTCCAAGGGAAT
CTGTAAAGAAATATATACTTGAGTGGTGTGTGTTATCAGATAAAGCACCCTGTATCACAGACTGGCAACAAGAAGATGGTACCGTGCATCGCACCTATTT
AAGAGGGAACTTAGCAGAGAGCAAATGCTATTTGATAACAGTTACTCCAGTATATGCTGATGGACCAGGAAGCCCTGAATCCATAAAGGCATACCTTAAA
CAAGCTCCACCTTCCAAAGGACCTACTGTTCGGACAAAAAAAGTAGGGAAAAACGAAGCTGTCTTAGAGTGGGACCAACTTCCTGTTGATGTTCAGAATG
GATTTATCAGAAATTATACTATATTTTATAGAACCATCATTGGAAATGAAACTGCTGTGAATGTGGATTCTTCCCACACAGAATATACATTGTCCTCTTT
GACTAGTGACACATTGTACATGGTACGAATGGCAGCATACACAGATGAAGGTGGGAAGGATGGTCCAGAATTCACTTTTACTACCCCAAAGTTTGCTCAA
GGAGAAATTGAAGCCATAGTCGTGCCTGTTTGCTTAGCATTCCTATTGACAACTCTTCTGGGAGTGCTGTTCTGCTTTAATAAGCGAGACCTAATTAAAA
AACACATCTGGCCTAATGTTCCAGATCCTTCAAAGAGTCATATTGCCCAGTGGTCACCTCACACTCCTCCAAGGCACAATTTTAATTCAAAAGATCAAAT
GTATTCAGATGGCAATTTCACTGATGTAAGTGTTGTGGAAATAGAAGCAAATGACAAAAAGCCTTTTCCAGAAGATCTGAAATCATTGGACCTGTTCAAA
AAGGAAAAAATTAATACTGAAGGACACAGCAGTGGTATTGGGGGGTCTTCATGCATGTCATCTTCTAGGCCAAGCATTTCTAGCAGTGATGAAAATGAAT
CTTCACAAAACACTTCGAGCACTGTCCAGTATTCTACCGTGGTACACAGTGGCTACAGACACCAAGTTCCGTCAGTCCAAGTCTTCTCAAGATCCGAGTC
TACCCAGCCCTTGTTAGATTCAGAGGAGCGGCCAGAAGATCTACAATTAGTAGATCATGTAGATGGCGGTGATGGTATTTTGCCCAGGCAACAGTACTTC
AAACAGAACTGCAGTCAGCATGAATCCAGTCCAGATATTTCACATTTTGAAAGGTCAAAGCAAGTTTCATCAGTCAATGAGGAAGATTTTGTTAGACTTA
AACAGCAGATTTCAGATCATATTTCACAATCCTGTGGATCTGGGCAAATGAAAATGTTTCAGGAAGTTTCTGCAGCAGATGCTTTTGGTCCAGGTACTGA
GGGACAAGTAGAAAGATTTGAAACAGTTGGCATGGAGGCTGCGACTGATGAAGGCATGCCTAAAAGTTACTTACCACAGACTGTACGGCAAGGCGGCTAC
ATGCCTCAGTGAAGGACTAGTAGTTCCTGCTACAACTTCAGCAGTACCTATAAAGTAAAGCTAAAATGATTTTATCTGTGAATTCAGATTTTAAAAAGTC
TTCACTCTCTGAAGATGATCATTTGCCCTTAAGGACAAAAATGAACTGAAGTTTCACATGAGCTATTTCCATTCCAGAATATCTGGGATTCTACTTTAAG
CACTACATAAACTGACTTTATCCTCAGA
  • refseq_IL6ST.F1 (forward primer)
  • refseq_IL6ST.R1 (reverse primer)
  • Single exon skipping

Frame 0

EQPKGPRSRAGPPRRS*TGGRACQADGSGPAWR
QGVRALWRRGGSRRRGLSETQWKKHDI*K*KT*L
QIPTPSLTNFVIWKYPRKMLTLQTWLVQALFIF
LTTESTGELLDPCGYISPESPVVQLHSNFTAVC
VLKEKCMDYFHVNANYIVWKTNHFTIPKEQYTII
NRTASSVTFTDIASLNIQLTCNILTFGQLEQNV
YGITIISGLPPEKPKNLSCIVNEGKKMRCEWDG
GRETHLETNFTLKSEWATHKFADCKAKRDTPTSC
TVDYSTVYFVNIEVWVEAENALGKVTSDHINFD
PVYKVKPNPPHNLSVINSEELSSILKLTWTNPS
IKSVIILKYNIQYRTKDASTWSQIPPEDTASTRS
SFTVQDLKPFTEYVFRIRCMKEDGKGYWSDWSE
EASGITYEDRPSKAPSFWYKIDPSHTQGYRTVQ
LVWKTLPPFEANGKILDYEVTLTRWKSHLQNYTV
NATKLTVNLTNDRYLATLTVRNLVGKSDAAVLT
IPACDFQATHPVMDLKAFPKDNMLWVEWTTPRE
SVKKYILEWCVLSDKAPCITDWQQEDGTVHRTYL
RGNLAESKCYLITVTPVYADGPGSPESIKAYLK
QAPPSKGPTVRTKKVGKNEAVLEWDQLPVDVQN
GFIRNYTIFYRTIIGNETAVNVDSSHTEYTLSSL
TSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQ
GEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIK
KHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQM
YSDGNFTDVSVVEIEANDKKPFPEDLKSLDLFK
KEKINTEGHSSGIGGSSCMSSSRPSISSSDENE
SSQNTSSTVQYSTVVHSGYRHQVPSVQVFSRSES
TQPLLDSEERPEDLQLVDHVDGGDGILPRQQYF
KQNCSQHESSPDISHFERSKQVSSVNEEDFVRL
KQQISDHISQSCGSGQMKMFQEVSAADAFGPGTE
GQVERFETVGMEAATDEGMPKSYLPQTVRQGGY
MPQ*RTSSSCYNFSSTYKVKLK*FYL*IQILKS
LHSLKMIICP*GQK*TEVSHELFPFQNIWDSTLS
TT*TDFILR

Frame 1

SSQKARGVALGRPGAAEPGAAPARPTGLAQPGA
KGFVRCGDAEGRGGAA*VKPNGKSMTFRSRRLS
FKSLLLHLLIL*FGNIRARC*RCRLG*CKPCLFS
SPLNLQVNF*IHVVISVLNLQLYNFILISLQFV
C*RKNVWIIFM*MLITLSGKQTILLFLRSNILS
*TEQHPVSPLQI*LH*IFSSLATFLHSDSLNRMF
MESQ*FQACLQKNLKI*VAL*TRGRK*GVSGMV
EGKHTWRQTSL*NLNGQHTSLLIAKQNVTPPPH
ALLIILLCILSTLKSG*KQRMPLGRLHQIISILI
LYIK*SPIRHIIYQ*STQRNCLVS*N*HGPTQV
LRVL*Y*NITFNIGPKMPQLGARFLLKTQHPPD
LHSLSKTLNLLQNMCLGFAV*RKMVRDTGVTGVK
KQVGSPMKIDHLKHQVSGIK*IHPILKATELYN
SCGRHCLLLKPMEKSWIMK*LSQDGNHIYKITQ
LMPQN*Q*ISQMIAI*QP*Q*EILLANQMQLF*L
SLPVTFKLLTL*WILKHSPKITCFGWNGLLQGN
L*RNIYLSGVCYQIKHPVSQTGNKKMVPCIAPI
*EGT*QRANAI**QLLQYMLMDQEALNP*RHTLN
KLHLPKDLLFGQKK*GKTKLS*SGTNFLLMFRM
DLSEIILYFIEPSLEMKLL*MWILPTQNIHCPL
*LVTHCTWYEWQHTQMKVGRMVQNSLLLPQSLLK
EKLKP*SCLFA*HSY*QLFWECCSALISET*LK
NTSGLMFQILQRVILPSGHLTLLQGTILIQKIK
CIQMAISLM*VLWK*KQMTKSLFQKI*NHWTCSK
RKKLILKDTAVVLGGLHACHLLGQAFLAVMKMN
LHKTLRALSSILPWYTVATDTKFRQSKSSQDPS
LPSPC*IQRSGQKIYN**IM*MAVMVFCPGNSTS
NRTAVSMNPVQIFHILKGQSKFHQSMRKILLDL
NSRFQIIFHNPVDLGK*KCFRKFLQQMLLVQVL
RDK*KDLKQLAWRLRLMKACLKVTYHRLYGKAAT
CLSEGLVVPATTSAVPIK*S*NDFICEFRF*KV
FTL*R*SFALKDKNELKFHMSYFHSRISGILL*
ALHKLTLSS

Frame 2

AAKRPAESRWAAPAQLNRGPRLPGRRVWPSLAP
RGSCAVETRRVEAARPE*NPMEKA*HLEVEDLA
SNPYSFTY*FCDLEISAQDVDVADLASASLVYF
PHH*IYR*TSRSMWLYQS*ISSCTTSF*FHCSLC
AKGKMYGLFSCKC*LHCLENKPFYYS*GAIYYH
KQNSIQCHLYRYSFIKYSAHLQHSYIRTA*TEC
LWNHNNFRLASRKT*KFELHCERGEENEV*VGWW
KGNTLGDKLHFKI*MGNTQVC*LQSKT*HPHLM
HC*LFYCVFCQH*SLGRSRECPWEGYIRSYQF*
SCI*SEAQSAT*FISDQLRGTV*YLKIDMDQPKY
*ECYNTKI*HSI*DQRCLNLEPDSS*RHSIHPI
FIHCPRP*TFYRICV*DSLYEGRW*GILE*LE*
RSKWDHL*R*TI*STKFLV*NRSIPYSRLQNCTT
RVEDIASF*SQWKNLGL*SDSHKMEITFTKLHS
*CHKTDSKSHK*SLSSNPNSKKSCWQIRCSCFN
YPCL*LSSYSPCNGS*SIPQR*HALGGMDYSKGI
CKEIYT*VVCVIR*STLYHRLATRRWYRASHLF
KRELSREQMLFDNSYSSIC*WTRKP*IHKGIP*
TSSTFQRTYCSDKKSREKRSCLRVGPTSC*CSEW
IYQKLYYIL*NHHWK*NCCECGFFPHRIYIVLF
D**HIVHGTNGSIHR*RWEGWSRIHFYYPKVCS
RRN*SHSRACLLSIPIDNSSGSAVLL**ARPN*K
THLA*CSRSFKESYCPVVTSHSSKAQF*FKRSN
VFRWQFH*CKCCGNRSK*QKAFSRRSEIIGPVQ
KGKN*Y*RTQQWYWGVFMHVIF*AKHF*Q**K*I
FTKHFEHCPVFYRGTQWLQTPSSVSPSLLKIRV
YPALVRFRGAARRSTISRSCRWR*WYFAQATVL
QTELQSA*IQSRYFTF*KVKASFISQ*GRFC*T*
TADFRSYFTILWIWANENVSGSFCSRCFWSRY*
GTSRKI*NSWHGGCD**RHA*KLLTTDCTARRL
HASVKD**FLLQLQQYL*SKAKMILSVNSDFKKS
SLSEDDHLPLRTKMN*SFT*AISIPEYLGFYFK
HYIN*LYPQ

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