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Sequences

Sequence NM_005033

GATGACGTAATTTTCCTGCGCCTCGGGGCGAGCAGCGGCGCGCAAGGAAAGATCGGGTTCCGTTTTTCCCGCGGATTCTGGTGCCTGTGGGGCCGGTGAC
CCAACACCATGAAGGAAACGCCACTCTCAAACTGCGAACGCCGCTTCCTACTCCGTGCCATCGAAGAGAAGAAGCGGCTGGATGGCAGACAAACCTATGA
TTATAGGAACATCAGGATCTCATTTGGAACAGATTACGGATGCTGCATTGTGGAACTTGGAAAAACAAGAGTTCTTGGACAGGTTTCCTGTGAACTTGTG
TCTCCAAAACTCAATCGGGCAACAGAAGGTATTCTTTTTTTTAACCTTGAACTCTCTCAGATGGCCGCTCCAGCTTTCGAACCTGGCAGGCAGTCAGATC
TCTTGGTGAAGTTGAATCGACTCATGGAAAGATGTCTAAGAAATTCGAAGTGTATAGACACTGAGTCTCTCTGTGTTGTTGCTGGTGAAAAGGTTTGGCA
AATACGTGTAGACCTACATTTATTAAATCATGATGGAAATATTATTGATGCTGCCAGCATTGCTGCAATCGTGGCCTTATGTCATTTCCGAAGACCTGAT
GTCTCTGTCCAAGGAGATGAAGTAACACTGTATACACCTGAAGAGCGTGATCCTGTACCATTAAGTATCCACCACATGCCCATTTGTGTCAGTTTTGCCT
TTTTCCAGCAAGGAACATATTTATTGGTGGATCCCAATGAACGAGAAGAACGTGTGATGGATGGCTTGCTGGTGATTGCCATGAACAAACATCGAGAGAT
TTGTACTATCCAGTCCAGTGGTGGGATAATGCTACTAAAAGATCAAGTTCTGAGATGCAGTAAAATCGCTGGTGTGAAAGTAGCAGAAATTACAGAGCTA
ATATTGAAAGCTTTGGAGAATGACCAAAAAGTAAGGAAAGAAGGTGGAAAGTTTGGTTTTGCAGAGTCTATAGCAAATCAAAGGATCACAGCATTTAAAA
TGGAAAAGGCCCCTATTGATACCTCGGATGTAGAAGAAAAAGCAGAAGAAATCATTGCTGAAGCAGAACCTCCTTCAGAAGTTGTTTCTACACCTGTGCT
ATGGACTCCTGGAACTGCCCAAATTGGAGAGGGAGTAGAAAACTCCTGGGGTGATCTTGAAGACTCTGAGAAGGAAGATGATGAAGGCGGTGGTGATCAA
GCTATCAT
TCTTGATGGTATAAAAATGGACACTGGAGTAGAAGTCTCTGATATTGGAAGCCAAGATGCTCCCATAATACTCTCAGATAGTGAAGAAGAAG
AAATGATCATTTTGGAACCAGACAAGAATCCAAAGAAAATAAGAACACAGACCACCAGTGCAAAACAAGAAAAAGCACCAAGTAAAAAGCCAGTGAAAAG
AAGAAAAAAGAAGAGAGCTGCCAATTAAAGCTAACAGTTGTATATCTGTATATATAACTATTAAAAGGGATATTTATTCCATTCTGAGAACCCTGGGTAT
TTTTTATTCACAAATCCATTATAAAATCTAGCAGGATTTTAAAAATAGTTTTTTGTTTTTAATGTGCTTTAAAATAATAAACCTTCTGGAGCA
  • refseq_EXOSC9.F1 (forward primer)
  • refseq_EXOSC9.R1 (reverse primer)
  • Single exon skipping

Frame 0

DDVIFLRLGASSGAQGKIGFRFSRGFWCLWGR*
PNTMKETPLSNCERRFLLRAIEEKKRLDGRQTYD
YRNIRISFGTDYGCCIVELGKTRVLGQVSCELV
SPKLNRATEGILFFNLELSQMAAPAFEPGRQSD
LLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQ
IRVDLHLLNHDGNIIDAASIAAIVALCHFRRPD
VSVQGDEVTLYTPEERDPVPLSIHHMPICVSFA
FFQQGTYLLVDPNEREERVMDGLLVIAMNKHREI
CTIQSSGGIMLLKDQVLRCSKIAGVKVAEITEL
ILKALENDQKVRKEGGKFGFAESIANQRITAFK
MEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVL
WTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQ
AII
LDGIKMDTGVEVSDIGSQDAPIILSDSEEE
EMIILEPDKNPKKIRTQTTSAKQEKAPSKKPVKR
RKKKRAAN*S*QLYICIYNY*KGYLFHSENPGY
FLFTNPL*NLAGF*K*FFVFNVL*NNKPSGA

Frame 1

MT*FSCASGRAAARKERSGSVFPADSGACGAGD
PTP*RKRHSQTANAASYSVPSKRRSGWMADKPM
IIGTSGSHLEQITDAALWNLEKQEFLDRFPVNLC
LQNSIGQQKVFFFLTLNSLRWPLQLSNLAGSQI
SW*S*IDSWKDV*EIRSV*TLSLSVLLLVKRFG
KYV*TYIY*IMMEILLMLPALLQSWPYVISEDLM
SLSKEMK*HCIHLKSVILYH*VSTTCPFVSVLP
FSSKEHIYWWIPMNEKNV*WMACW*LP*TNIER
FVLSSPVVG*CY*KIKF*DAVKSLV*K*QKLQS*
Y*KLWRMTKK*GKKVESLVLQSL*QIKGSQHLK
WKRPLLIPRM*KKKQKKSLLKQNLLQKLFLHLC
YGLLELPKLERE*KTPGVILKTLRRKMMKAVVIK
LS
FLMV*KWTLE*KSLILEAKMLP*YSQIVKKK
K*SFWNQTRIQRK*EHRPPVQNKKKHQVKSQ*K
EEKRRELPIKANSCISVYITIKRDIYSILRTLGI
FYSQIHYKI*QDFKNSFLFLMCFKIINLLE

Frame 2

*RNFPAPRGEQRRARKDRVPFFPRILVPVGPVT
QHHEGNATLKLRTPLPTPCHRREEAAGWQTNL*
L*EHQDLIWNRLRMLHCGTWKNKSSWTGFL*TC
VSKTQSGNRRYSFF*P*TLSDGRSSFRTWQAVRS
LGEVESTHGKMSKKFEVYRH*VSLCCCW*KGLA
NTCRPTFIKS*WKYY*CCQHCCNRGLMSFPKT*
CLCPRR*SNTVYT*RA*SCTIKYPPHAHLCQFCL
FPARNIFIGGSQ*TRRTCDGWLAGDCHEQTSRD
LYYPVQWWDNATKRSSSEMQ*NRWCESSRNYRA
NIESFGE*PKSKERRWKVWFCRVYSKSKDHSI*N
GKGPY*YLGCRRKSRRNHC*SRTSFRSCFYTCA
MDSWNCPNWRGSRKLLG*S*RL*EGR**RRW*S
SYH
S*WYKNGHWSRSL*YWKPRCSHNTLR**RRR
NDHFGTRQESKENKNTDHQCKTRKSTK*KASEK
KKKEESCQLKLTVVYLYI*LLKGIFIPF*EPWV
FFIHKSIIKSSRILKIVFCF*CALK**TFWS

Sequence NM_001034194

GATGACGTAATTTTCCTGCGCCTCGGGGCGAGCAGCGGCGCGCAAGGAAAGATCGGGTTCCGTTTTTCCCGCGGATTCTGGTGCCTGTGGGGCCGGTGAC
CCAACACCATGAAGGAAACGCCACTCTCAAACTGCGAACGCCGCTTCCTACTCCGTGCCATCGAAGAGAAGAAGCGGCTGGATGGCAGACAAACCTATGA
TTATAGGAACATCAGGATCTCATTTGGAACAGATTACGGATGCTGCATTGTGGAACTTGGAAAAACAAGAGTTCTTGGACAGGTTTCCTGTGAACTTGTG
TCTCCAAAACTCAATCGGGCAACAGAAGGTATTCTTTTTTTTAACCTTGAACTCTCTCAGATGGCCGCTCCAGCTTTCGAACCTGGCAGGCAGTCAGATC
TCTTGGTGAAGTTGAATCGACTCATGGAAAGATGTCTAAGAAATTCGAAGTGTATAGACACTGAGTCTCTCTGTGTTGTTGCTGGTGAAAAGGTTTGGCA
AATACGTGTAGACCTACATTTATTAAATCATGATGGAAATATTATTGATGCTGCCAGCATTGCTGCAATCGTGGCCTTATGTCATTTCCGAAGACCTGAT
GTCTCTGTCCAAGGAGATGAAGTAACACTGTATACACCTGAAGAGCGTGATCCTGTACCATTAAGTATCCACCACATGCCCATTTGTGTCAGTTTTGCCT
TTTTCCAGCAAGGAACATATTTATTGGTGGATCCCAATGAACGAGAAGAACGTGTGATGGATGGCTTGCTGGTGATTGCCATGAACAAACATCGAGAGAT
TTGTACTATCCAGTCCAGTGGTGGGATAATGCTACTAAAAGATCAAGTTCTGAGATGCAGTAAAATCGCTGGTGTGAAAGTAGCAGAAATTACAGAGCTA
ATATTGAAAGCTTTGGAGAATGACCAAAAAGTAAGGAAAGAAGGTGGAAAGTTTGGTTTTGCAGAGTCTATAGCAAATCAAAGGATCACAGCATTTAAAA
TGGAAAAGGCCCCTATTGATACCTCGGATGTAGAAGAAAAAGCAGAAGAAATCATTGCTGAAGCAGAACCTCCTTCAGAAGTTGTTTCTACACCTGTGCT
ATGGACTCCTGGAACTGCCCAAATTGGAGAGGGAGTAGAAAACTCCTGGGGTGATCTTGAAGACTCTGAGAAGGAAGATGATGAAGGCGGTGGTGATCAA
GCTATCAT
TCTTGATGGTATAAAAATGGACACTGGAGTAGAAGTCTCTGATATTGGAAGCCAAGAGCTGGGGTTTCACCATGTTGGCCAGACTGGACTCG
AGTTCCTGACCTCAG
ATGCTCCCATAATACTCTCAGATAGTGAAGAAGAAGAAATGATCATTTTGGAACCAGACAAGAATCCAAAGAAAATAAGAACACA
GACCACCAGTGCAAAACAAGAAAAAGCACCAAGTAAAAAGCCAGTGAAAAGAAGAAAAAAGAAGAGAGCTGCCAATTAAAGCTAACAGTTGTATATCTGT
ATATATAACTATTAAAAGGGATATTTATTCCATTCTGAGAACCCTGGGTATTTTTTATTCACAAATCCATTATAAAATCTAGCAGGATTTTAAAAATAGT
TTTTTGTTTTTAATGTGCTTTAAAATAATAAACCTTCTGGAGCA
  • refseq_EXOSC9.F1 (forward primer)
  • refseq_EXOSC9.R1 (reverse primer)
  • Single exon skipping

Frame 0

DDVIFLRLGASSGAQGKIGFRFSRGFWCLWGR*
PNTMKETPLSNCERRFLLRAIEEKKRLDGRQTYD
YRNIRISFGTDYGCCIVELGKTRVLGQVSCELV
SPKLNRATEGILFFNLELSQMAAPAFEPGRQSD
LLVKLNRLMERCLRNSKCIDTESLCVVAGEKVWQ
IRVDLHLLNHDGNIIDAASIAAIVALCHFRRPD
VSVQGDEVTLYTPEERDPVPLSIHHMPICVSFA
FFQQGTYLLVDPNEREERVMDGLLVIAMNKHREI
CTIQSSGGIMLLKDQVLRCSKIAGVKVAEITEL
ILKALENDQKVRKEGGKFGFAESIANQRITAFK
MEKAPIDTSDVEEKAEEIIAEAEPPSEVVSTPVL
WTPGTAQIGEGVENSWGDLEDSEKEDDEGGGDQ
AII
LDGIKMDTGVEVSDIGSQELGFHHVGQTGL
EFLTS
DAPIILSDSEEEEMIILEPDKNPKKIRTQ
TTSAKQEKAPSKKPVKRRKKKRAAN*S*QLYIC
IYNY*KGYLFHSENPGYFLFTNPL*NLAGF*K*
FFVFNVL*NNKPSGA

Frame 1

MT*FSCASGRAAARKERSGSVFPADSGACGAGD
PTP*RKRHSQTANAASYSVPSKRRSGWMADKPM
IIGTSGSHLEQITDAALWNLEKQEFLDRFPVNLC
LQNSIGQQKVFFFLTLNSLRWPLQLSNLAGSQI
SW*S*IDSWKDV*EIRSV*TLSLSVLLLVKRFG
KYV*TYIY*IMMEILLMLPALLQSWPYVISEDLM
SLSKEMK*HCIHLKSVILYH*VSTTCPFVSVLP
FSSKEHIYWWIPMNEKNV*WMACW*LP*TNIER
FVLSSPVVG*CY*KIKF*DAVKSLV*K*QKLQS*
Y*KLWRMTKK*GKKVESLVLQSL*QIKGSQHLK
WKRPLLIPRM*KKKQKKSLLKQNLLQKLFLHLC
YGLLELPKLERE*KTPGVILKTLRRKMMKAVVIK
LS
FLMV*KWTLE*KSLILEAKSWGFTMLARLDS
SS*PQ
MLP*YSQIVKKKK*SFWNQTRIQRK*EH
RPPVQNKKKHQVKSQ*KEEKRRELPIKANSCISV
YITIKRDIYSILRTLGIFYSQIHYKI*QDFKNS
FLFLMCFKIINLLE

Frame 2

*RNFPAPRGEQRRARKDRVPFFPRILVPVGPVT
QHHEGNATLKLRTPLPTPCHRREEAAGWQTNL*
L*EHQDLIWNRLRMLHCGTWKNKSSWTGFL*TC
VSKTQSGNRRYSFF*P*TLSDGRSSFRTWQAVRS
LGEVESTHGKMSKKFEVYRH*VSLCCCW*KGLA
NTCRPTFIKS*WKYY*CCQHCCNRGLMSFPKT*
CLCPRR*SNTVYT*RA*SCTIKYPPHAHLCQFCL
FPARNIFIGGSQ*TRRTCDGWLAGDCHEQTSRD
LYYPVQWWDNATKRSSSEMQ*NRWCESSRNYRA
NIESFGE*PKSKERRWKVWFCRVYSKSKDHSI*N
GKGPY*YLGCRRKSRRNHC*SRTSFRSCFYTCA
MDSWNCPNWRGSRKLLG*S*RL*EGR**RRW*S
SYH
S*WYKNGHWSRSL*YWKPRAGVSPCWPDWTR
VPDLR
CSHNTLR**RRRNDHFGTRQESKENKNT
DHQCKTRKSTK*KASEKKKKEESCQLKLTVVYL
YI*LLKGIFIPF*EPWVFFIHKSIIKSSRILKIV
FCF*CALK**TFWS

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