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Sequences

Sequence NM_001002269

GGAAACGGTGTTTGGTGGAGCCCGCGATGGCCGAACCTGCGTCTGTCGCGGCTGAATCTCTCGCGGGCAGCAGGGCGCGCGCTGCACGCACAGTACTAGG
TCAGGTGGTGCTCCCGGGTGAGGAGCTGCTCCTGCCGGAACAGGAGGACGCGGAAGGCCCTGGGGGTGCAGTGGAGCGACCGTTGAGCCTGAATGCTAGA
GCGTGCTCGCGGGTGCGCGTTGTATGCGGTCCGGGCCTTCGGCGCTGTGGGGACCGCCTGCTGGTCACCAAGTGCGGCCGCCTCCGTCACAAGGAGCCCG
GCAGTGGCAGCGGCGGCGGTGTTTACTGGGTGGACTCTCAGCAGAAGCGGTATGTTCCAGTAAAAGGAGACCATGTGATTGGCATAGTGACAGCTAAATC
TGGAGATATATTCAAAGTTGATGTTGGAGGGAGTGAGCCAGCTTCTTTGTCTTACTTGTCATTTGAAGGTGCAACTAAAAGAAACAGACCAAATGTGCAG
GCTATTAGCTCCAGATTGTGAAATCATACAGGAAGTGGGAAAACTCTATCCACTGGAGATAGTATTTGGAATGAATGGAAGAATATGGGTTAAGGCAAAA
ACCATCCAGCAGACTTTAATTTTGGCAAACATTTTAGAAGCTTGTGAACACATGACGTCAGATCAAAGAAAACAGATCTTCTCCAGATTGGCAGAAAGTT
GATATAGGTGGACTTTTTTACAGGTCAGTTGAGGCAAAAAACTATGGGTTTTTTCAGGTGAACCTCCCCCATTTAAATACTCAGAAGATAAGGTGTGAAT
GTATGTATTATTAGAGTCCGAAAGTATTTTTATAAGTTACTGGTTTTCACCCACGCTTTTGTGGGAGAGAAAATCATTGCAAAATCATTTTTTTTGTTCG
GTACAATAAAGTTTACTAAAAAACAGTATTAGGGTTTATTTGGAGTTAACTCCCTTAGTAATTGCTACAGCTTCCATAATTAACTGGAGGTCAGCAGTAA
AATAATTTTGTGATTATAACAGTAAGCCAGGTTCACCAGAGGAAATGTGGAATACCTAAGTATAAAGCAG
  • refseq_EXOSC3.F1 (forward primer)
  • refseq_EXOSC3.R1 (reverse primer)
  • Single exon skipping

Frame 0

GNGVWWSPRWPNLRLSRLNLSRAAGRALHAQY*
VRWCSRVRSCSCRNRRTRKALGVQWSDR*A*MLE
RARGCALYAVRAFGAVGTACWSPSAAASVTRSP
AVAAAAVFTGWTLSRSGMFQ*KETM*LA**QLN
LEIYSKLMLEGVSQLLCLTCHLKVQLKETDQMCR
LLAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAK
TIQQTLILANILEACEHMTSDQRKQIFSRLAES
*YRWTFLQVS*GKKLWVFSGEPPPFKYSEDKV*M
YVLLESESIFISYWFSPTLLWERKSLQNHFFCS
VQ*SLLKNSIRVYLELTPLVIATASIINWRSAV
K*FCDYNSKPGSPEEMWNT*V*S

Frame 1

ETVFGGARDGRTCVCRG*ISRGQQGARCTHSTR
SGGAPG*GAAPAGTGGRGRPWGCSGATVEPEC*
SVLAGARCMRSGPSALWGPPAGHQVRPPPSQGAR
QWQRRRCLLGGLSAEAVCSSKRRPCDWHSDS*I
WRYIQS*CWRE*ASFFVLLVI*RCN*KKQTKCA
GY*LQIVKSYRKWENSIHWR*YLE*MEEYGLRQK
PSSRL*FWQTF*KLVNT*RQIKENRSSPDWQKV
DIGGLFYRSVEAKNYGFFQVNLPHLNTQKIRCE
CMYY*SPKVFL*VTGFHPRFCGRENHCKIIFFVR
YNKVY*KTVLGFIWS*LP**LLQLP*LTGGQQ*
NNFVIITVSQVHQRKCGIPKYKA

Frame 2

KRCLVEPAMAEPASVAAESLAGSRARAARTVLG
QVVLPGEELLLPEQEDAEGPGGAVERPLSLNAR
ACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEP
GSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKS
GDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQ
AISSRL*NHTGSGKTLSTGDSIWNEWKNMG*GK
NHPADFNFGKHFRSL*THDVRSKKTDLLQIGRKL
I*VDFFTGQLRQKTMGFFR*TSPI*ILRR*GVN
VCIIRVRKYFYKLLVFTHAFVGEKIIAKSFFLF
GTIKFTKKQY*GLFGVNSLSNCYSFHN*LEVSSK
IIL*L*Q*ARFTRGNVEYLSIKQ

Sequence NM_016042

GGAAACGGTGTTTGGTGGAGCCCGCGATGGCCGAACCTGCGTCTGTCGCGGCTGAATCTCTCGCGGGCAGCAGGGCGCGCGCTGCACGCACAGTACTAGG
TCAGGTGGTGCTCCCGGGTGAGGAGCTGCTCCTGCCGGAACAGGAGGACGCGGAAGGCCCTGGGGGTGCAGTGGAGCGACCGTTGAGCCTGAATGCTAGA
GCGTGCTCGCGGGTGCGCGTTGTATGCGGTCCGGGCCTTCGGCGCTGTGGGGACCGCCTGCTGGTCACCAAGTGCGGCCGCCTCCGTCACAAGGAGCCCG
GCAGTGGCAGCGGCGGCGGTGTTTACTGGGTGGACTCTCAGCAGAAGCGGTATGTTCCAGTAAAAGGAGACCATGTGATTGGCATAGTGACAGCTAAATC
TGGAGATATATTCAAAGTTGATGTTGGAGGGAGTGAGCCAGCTTCTTTGTCTTACTTGTCATTTGAAGGTGCAACTAAAAGAAACAGACCAAATGTGCAG
GTTGGAGATCTCATCTATGGCCAGTTTGTGGTTGCTAATAAAGACATGGAACCAGAGATGGTCTGTATTGACAGCTGTGGACGAGCCAATGGAATGGGTG
TCATTGGACAGGATGGTCTGCTTTTTAAAGTGACTCTGGGCTTAATTAGAAAGCTATTAGCTCCAGATTGTGAAATCATACAGGAAGTGGGAAAACTCTA
TCCACTGGAGATAGTATTTGGAATGAATGGAAGAATATGGGTTAAGGCAAAAACCATCCAGCAGACTTTAATTTTGGCAAACATTTTAGAAGCTTGTGAA
CACATGACGTCAGATCAAAGAAAACAGATCTTCTCCAGATTGGCAGAAAGTTGATATAGGTGGACTTTTTTACAGGTCAGTTGAGGCAAAAAACTATGGG
TTTTTTCAGGTGAACCTCCCCCATTTAAATACTCAGAAGATAAGGTGTGAATGTATGTATTATTAGAGTCCGAAAGTATTTTTATAAGTTACTGGTTTTC
ACCCACGCTTTTGTGGGAGAGAAAATCATTGCAAAATCATTTTTTTTGTTCGGTACAATAAAGTTTACTAAAAAACAGTATTAGGGTTTATTTGGAGTTA
ACTCCCTTAGTAATTGCTACAGCTTCCATAATTAACTGGAGGTCAGCAGTAAAATAATTTTGTGATTATAACAGTAAGCCAGGTTCACCAGAGGAAATGT
GGAATACCTAAGTATAAAGCAG
  • refseq_EXOSC3.F1 (forward primer)
  • refseq_EXOSC3.R1 (reverse primer)
  • Single exon skipping

Frame 0

GNGVWWSPRWPNLRLSRLNLSRAAGRALHAQY*
VRWCSRVRSCSCRNRRTRKALGVQWSDR*A*MLE
RARGCALYAVRAFGAVGTACWSPSAAASVTRSP
AVAAAAVFTGWTLSRSGMFQ*KETM*LA**QLN
LEIYSKLMLEGVSQLLCLTCHLKVQLKETDQMCR
LEISSMASLWLLIKTWNQRWSVLTAVDEPMEWV
SLDRMVCFLK*LWA*LESY*LQIVKSYRKWENS
IHWR*YLE*MEEYGLRQKPSSRL*FWQTF*KLVN
T*RQIKENRSSPDWQKVDIGGLFYRSVEAKNYG
FFQVNLPHLNTQKIRCECMYY*SPKVFL*VTGF
HPRFCGRENHCKIIFFVRYNKVY*KTVLGFIWS*
LP**LLQLP*LTGGQQ*NNFVIITVSQVHQRKC
GIPKYKA

Frame 1

ETVFGGARDGRTCVCRG*ISRGQQGARCTHSTR
SGGAPG*GAAPAGTGGRGRPWGCSGATVEPEC*
SVLAGARCMRSGPSALWGPPAGHQVRPPPSQGAR
QWQRRRCLLGGLSAEAVCSSKRRPCDWHSDS*I
WRYIQS*CWRE*ASFFVLLVI*RCN*KKQTKCA
GWRSHLWPVCGC**RHGTRDGLY*QLWTSQWNGC
HWTGWSAF*SDSGLN*KAISSRL*NHTGSGKTL
STGDSIWNEWKNMG*GKNHPADFNFGKHFRSL*
THDVRSKKTDLLQIGRKLI*VDFFTGQLRQKTMG
FFR*TSPI*ILRR*GVNVCIIRVRKYFYKLLVF
THAFVGEKIIAKSFFLFGTIKFTKKQY*GLFGV
NSLSNCYSFHN*LEVSSKIIL*L*Q*ARFTRGNV
EYLSIKQ

Frame 2

KRCLVEPAMAEPASVAAESLAGSRARAARTVLG
QVVLPGEELLLPEQEDAEGPGGAVERPLSLNAR
ACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEP
GSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKS
GDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQ
VGDLIYGQFVVANKDMEPEMVCIDSCGRANGMG
VIGQDGLLFKVTLGLIRKLLAPDCEIIQEVGKLY
PLEIVFGMNGRIWVKAKTIQQTLILANILEACE
HMTSDQRKQIFSRLAES*YRWTFLQVS*GKKLW
VFSGEPPPFKYSEDKV*MYVLLESESIFISYWFS
PTLLWERKSLQNHFFCSVQ*SLLKNSIRVYLEL
TPLVIATASIINWRSAVK*FCDYNSKPGSPEEM
WNT*V*S

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