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Sequences

Sequence NM_021904

CGCTCCCCGCTCCCGTGGCTGCCGCCGCCCCGGGGAAGAAGAGACAGGGGTGGGGTTTGGGGGAAGCGAGAGAGGAGGGGAGAGACCCTGGCCAGGCTGG AGCCTGGATTCGAGGGGAGGAGGGACGGGAGGAGGAGAAAGGTGGAGGAGAAGGGAGGGGGGAGCGGGGAGGAGCGGCCGGGCCTGGGGCCTTGAGGCCC GGGGAGAGCCGGGGAGCCGGGCCCGCGCGCCGAGATGTTGCTGCTGCTGCTACTGGCGCCACTCTTCCTCCGCCCCCCGGGCGCGGGCGGGGCGCAGACC CCCAACGCCACCTCAGAAGGTTGCCAGATCATACACCCGCCCTGGGAAGGGGGCATCAGGTACCGGGGCCTGACTCGGGACCAGGTGAAGGCTATCAACT TCCTGCCAGTGGACTATGAGATTGAGTATGTGTGCCGGGGGGAGCGCGAGGTGGTGGGGCCCAAGGTCCGCAAGTGCCTGGCCAACGGCTCCTGGACAGA TATGGACACACCCAGCCGCTGTGTGAATCGAACGCCACACTCAGAACGGCGCGCAGTGTACATCGGGGCACTGTTTCCCATGAGCGGGGGCTGGCCAGGG GGCCAGGCCTGCCAGCCCGCGGTGGAGATGGCGCTGGAGGACGTGAATAGCCGCAGGGACATCCTGCCGGACTATGAGCTCAAGCTCATCCACCACGACA GCAAGTGTGATCCAGGCCAAGCCACCAAGTACCTATATGAGCTGCTCTACAACGACCCTATCAAGATCATCCTTATGCCTGGCTGCAGCTCTGTCTCCAC GCTGGTGGCTGAGGCTGCTAGGATGTGGAACCTCATTGTGCTTTCCTATGGCTCCAGCTCACCAGCCCTGTCAAACCGGCAGCGTTTCCCCACTTTCTTC CGAACGCACCCATCAGCCACACTCCACAACCCTACCCGCGTGAAACTCTTTGAAAAGTGGGGCTGGAAGAAGATTGCTACCATCCAGCAGACCACTGAGG TCTTCACTTCGACTCTGGACGACCTGGAGGAACGAGTGAAGGAGGCTGGAATTGAGATTACTTTCCGCCAGAGTTTCTTCTCAGATCCAGCTGTGCCCGT CAAAAACCTGAAGCGCCAGGATGCCCGAATCATCGTGGGACTTTTCTATGAGACTGAAGCCCGGAAAGTTTTTTGTGAGGTGTACAAGGAGCGTCTCTTT GGGAAGAAGTACGTCTGGTTCCTCATTGGGTGGTATGCTGACAATTGGTTCAAGATCTACGACCCTTCTATCAACTGCACAGTGGATGAGATGACTGAGG CGGTGGAGGGCCACATCACAACTGAGATTGTCATGCTGAATCCTGCCAATACCCGCAGCATTTCCAACATGACATCCCAGGAATTTGTGGAGAAACTAAC CAAGCGACTGAAAAGACACCCTGAGGAGACAGGAGGCTTCCAGGAGGCACCGCTGGCCTATGATGCCATCTGGGCCTTGGCACTGGCCCTGAACAAGACA TCTGGAGGAGGCGGCCGTTCTGGTGTGCGCCTGGAGGACTTCAACTACAACAACCAGACCATTACCGACCAAATCTACCGGGCAATGAACTCTTCGTCCT TTGAGGGTGTCTCTGGCCATGTGGTGTTTGATGCCAGCGGCTCTCGGATGGCATGGACGCTTATCGAGCAGCTTCAGGGTGGCAGCTACAAGAAGATTGG CTACTATGACAGCACCAAGGATGATCTTTCCTGGTCCAAAACAGATAAATGGATTGGAGGGTCCCCCCCAGCTGACCAGACCCTGGTCATCAAGACATTC CGCTTCCTGTCACAGAAACTCTTTATCTCCGTCTCAGTTCTCTCCAGCCTGGGCATTGTCCTAGCTGTTGTCTGTCTGTCCTTTAACATCTACAACTCAC ATGTCCGTTATATCCAGAACTCACAGCCCAACCTGAACAACCTGACTGCTGTGGGCTGCTCACTGGCTTTAGCTGCTGTCTTCCCCCTGGGGCTCGATGG TTACCACATTGGGAGGAACCAGTTTCCTTTCGTCTGCCAGGCCCGCCTCTGGCTCCTGGGCCTGGGCTTTAGTCTGGGCTACGGTTCCATGTTCACCAAG ATTTGGTGGGTCCACACGGTCTTCACAAAGAAGGAAGAAAAGAAGGAGTGGAGGAAGACTCTGGAACCCTGGAAGCTGTATGCCACAGTGGGCCTGCTGG TGGGCATGGATGTCCTCACTCTCGCCATCTGGCAGATCGTGGACCCTCTGCACCGGACCATTGAGACATTTGCCAAGGAGGAACCTAAGGAAGATATTGA CGTCTCTATTCTGCCCCAGCTGGAGCATTGCAGCTCCAGGAAGATGAATACATGGCTTGGCATTTTCTATGGTTACAAGGGGCTGCTGCTGCTGCTGGGA ATCTTCCTTGCTTATGAGACCAAGAGTGTGTCCACTGAGAAGATCAATGATCACCGGGCTGTGGGCATGGCTATCTACAATGTGGCAGTCCTGTGCCTCA TCACTGCTCCTGTCACCATGATTCTGTCCAGCCAGCAGGATGCAGCCTTTGCCTTTGCCTCTCTTGCCATAGTTTTCTCCTCCTATATCACTCTTGTTGT GCTCTTTGTGCCCAAGATGCGCAGGCTGATCACCCGAGGGGAATGGCAGTCGGAGGCGCAGGACACCATGAAGACAGGGTCATCGACCAACAACAACGAG GAGGAGAAGTCCCGGCTGTTGGAGAAGGAGAACCGTGAACTGGAAAAGATCATTGCTGAGAAAGAGGAGCGTGTCTCTGAACTGCGCCATCAACTCCAGT CTCGGCAGCAGCTCCGCTCCCGGCGCCACCCACCGACACCCCCAGAACCCTCTGGGGGCCTGCCCAGGGGACCCCCTGAGCCCCCCGACCGGCTTAGCTG TGATGGGAGTCGAGTGCATTTGCTTTATAAGTGAGGGTAGGGTGAGGGAGGACAGGCCAGTAGGGGGAGGGAAAGGGAGAGGGGAAGGGCAGGGGACTCA GGAAGCAGGGGGTCCCCATCCCCAGCTGGGAAGAACATGCTATCCAATCTCATCTCTTGTAAATACATGTCCCCCTGTGAGTTCTGGGCTGATTTGGGTC TCTCATACCTCTGGGAAACAGACCTTTTTCTCTCTTACTGCTTCATGTAATTTTGTATCACCTCTTCACAATTTAGTTCGTACCTGGCTTGAAGCTGCTC ACTGCTCACACGCTGCCTCCTCAGCAGCCTCACTGCATCTTTCTCTTCCCATGCAACACCCTCTTCTAGTTACCACGGCAACCCCTGCAGCTCCTCTGCC TTTGTGCTCTGTTCCTGTCCAGCAGGGGTCTCCCAACAAGTGCTCTTTCCACCCCAAAGGGGCCTCTCCTTTTCTCCACTGTCATAATCTCTTTCCATCT TACTTGCCCTTCTATACTTTCTCACATGTGGCTCCCCCTGAATTTTGCTTCCTTTGGGAGCTCATTCTTTTCGCCAAGGCTCACATGCTCCTTGCCTCTG CTCTGTGCACTCACGCTCAGCACACATGCATCCTCCCCTCTCCTGCGTGTGCCCACTGAACATGCTCATGTGTACACACGCTTTTCCCGTATGCTTTCTT CATGTTCAGTCACATGTGCTCTCGGGTGCCCTGCATTCACAGCTACGTGTGCCCCTCTCATGGTCATGGGTCTGCCCTTGAGCGTGTTTGGGTAGGCATG TGCAATTTGTCTAGCATGCTGAGTCATGTCTTTCCTATTTGCACACGTCCATGTTTATCCATGTACTTTCCCTGTGTACCCTCCATGTACCTTGTGTACT TTCTTCCCTTAAATCATGGTATTCTTCTGACAGAGCCATATGTACCCTACCCTGCACATTGTTATGCACTTTTCCCCAATTCATGTTTGGTGGGGCCATC CACACCCTCTCCTTGTCACAGAATCTCCATTTCTGCTCAGATTCCCCCCATCTCCATTGCATTCATGTACTACCCTCAGTCTACACTCACAATCATCTTC TCCCAAGACTGCTCCCTTTTGTTTTGTGTTTTTTTGAGGGGAATTAAGGAAAAATAAGTGGGGGCAGGTTTGGAGAGCTGCTTCCAGTGGATAGTTGATG AGAATCCTGACCAAAGGAAGGCACCCTTGACTGTTGGGATAGACAGATGGACCTATGGGGTGGGAGGTGGTGTCCCTTTCACACTGTGGTGTCTCTTGGG GAAGGATCTCCCCGAATCTCAATAAACCAGTGAACAGTGTGACTCGGCA

refseq_GABBR1.F1 (forward primer)
refseq_GABBR1.R1 (reverse primer)
Single exon skipping

Frame 0

RSPLPWLPPPRGRRDRGGVWGKRERRGETLARL EPGFEGRRDGRRRKVEEKGGGSGEERPGLGP*GP GRAGEPGPRAEMLLLLLLAPLFLRPPGAGGAQT PNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTD MDTPSRCVNRTPHSERRAVYIGALFPMSGGWPG GQACQPAVEMALEDVNSRRDILPDYELKLIHHD SKCDPGQATKYLYELLYNDPIKIILMPGCSSVST LVAEAARMWNLIVLSYGSSSPALSNRQRFPTFF RTHPSATLHNPTRVKLFEKWGWKKIATIQQTTE VFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPV KNLKRQDARIIVGLFYETEARKVFCEVYKERLF GKKYVWFLIGWYADNWFKIYDPSINCTVDEMTE AVEGHITTEIVMLNPANTRSISNMTSQEFVEKLT KRLKRHPEETGGFQEAPLAYDAIWALALALNKT SGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSS FEGVSGHVVFDASGSRMAWTLIEQLQGGSYKKIG YYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTF RFLSQKLFISVSVLSSLGIVLAVVCLSFNIYNS HVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDG YHIGRNQFPFVCQARLWLLGLGFSLGYGSMFTK IWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLL VGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDID VSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLG IFLAYETKSVSTEKINDHRAVGMAIYNVAVLCL ITAPVTMILSSQQDAAFAFASLAIVFSSYITLVV LFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNE EEKSRLLEKENRELEKIIAEKEERVSELRHQLQ SRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSC DGSRVHLLYK*G*GEGGQASRGRERERGRAGDS GSRGSPSPAGKNMLSNLISCKYMSPCEFWADLG LSYLWETDLFLSYCFM*FCITSSQFSSYLA*SCS LLTRCLLSSLTASFSSHATPSSSYHGNPCSSSA FVLCSCPAGVSQQVLFPPQRGLSFSPLS*SLSI LLALLYFLTCGSP*ILLPLGAHSFRQGSHAPCLC SVHSRSAHMHPPLSCVCPLNMLMCTHAFPVCFL HVQSHVLSGALHSQLRVPLSWSWVCP*ACLGRH VQFV*HAESCLSYLHTSMFIHVLSLCTLHVPCVL SSLKSWYSSDRAICTLPCTLLCTFPQFMFGGAI HTLSLSQNLHFCSDSPHLHCIHVLPSVYTHNHL LPRLLPFVLCFFEGN*GKISGGRFGELLPVDS** ES*PKEGTLDCWDRQMDLWGGRWCPFHTVVSLG EGSPRISINQ*TV*LG

Frame 1

APRSRGCRRPGEEETGVGFGGSERGGERPWPGW SLDSRGGGTGGGERWRRREGGAGRSGRAWGLEA RGEPGSRARAPRCCCCCYWRHSSSAPRARAGRRP PTPPQKVARSYTRPGKGASGTGA*LGTR*RLST SCQWTMRLSMCAGGSARWWGPRSASAWPTAPGQ IWTHPAAV*IERHTQNGAQCTSGHCFP*AGAGQG ARPASPRWRWRWRT*IAAGTSCRTMSSSSSTTT ASVIQAKPPSTYMSCSTTTLSRSSLCLAAALSP RWWLRLLGCGTSLCFPMAPAHQPCQTGSVSPLSS ERTHQPHSTTLPA*NSLKSGAGRRLLPSSRPLR SSLRLWTTWRNE*RRLELRLLSARVSSQIQLCP SKT*SARMPESSWDFSMRLKPGKFFVRCTRSVSL GRSTSGSSLGGMLTIGSRSTTLLSTAQWMR*LR RWRATSQLRLSC*ILPIPAAFPT*HPRNLWRN* PSD*KDTLRRQEASRRHRWPMMPSGPWHWP*TRH LEEAAVLVCAWRTSTTTTRPLPTKSTGQ*TLRP LRVSLAMWCLMPAALGWHGRLSSSFRVAATRRL ATMTAPRMIFPGPKQINGLEGPPQLTRPWSSRHS ASCHRNSLSPSQFSPAWALS*LLSVCPLTSTTH MSVISRTHSPT*TT*LLWAAHWL*LLSSPWGSM VTTLGGTSFLSSARPASGSWAWALVWATVPCSPR FGGSTRSSQRRKKRRSGGRLWNPGSCMPQWACW WAWMSSLSPSGRSWTLCTGPLRHLPRRNLRKIL TSLFCPSWSIAAPGR*IHGLAFSMVTRGCCCCWE SSLLMRPRVCPLRRSMITGLWAWLSTMWQSCAS SLLLSP*FCPASRMQPLPLPLLP*FSPPISLLL CSLCPRCAG*SPEGNGSRRRRTP*RQGHRPTTTR RRSPGCWRRRTVNWKRSLLRKRSVSLNCAINSS LGSSSAPGATHRHPQNPLGACPGDPLSPPTGLA VMGVECICFISEGRVREDRPVGGGKGRGEGQGTQ EAGGPHPQLGRTCYPISSLVNTCPPVSSGLIWV SHTSGKQTFFSLTASCNFVSPLHNLVRTWLEAA HCSHAASSAASLHLSLPMQHPLLVTTATPAAPLP LCSVPVQQGSPNKCSFHPKGASPFLHCHNLFPS YLPFYTFSHVAPPEFCFLWELILFAKAHMLLAS ALCTHAQHTCILPSPACAH*TCSCVHTLFPYAFF MFSHMCSRVPCIHSYVCPSHGHGSALERVWVGM CNLSSMLSHVFPICTRPCLSMYFPCVPSMYLVY FLPLNHGILLTEPYVPYPAHCYALFPNSCLVGPS TPSPCHRISISAQIPPISIAFMYYPQSTLTIIF SQDCSLLFCVFLRGIKEK*VGAGLESCFQWIVD ENPDQRKAPLTVGIDRWTYGVGGGVPFTLWCLLG KDLPESQ*TSEQCDSA

Frame 2

LPAPVAAAAPGKKRQGWGLGEAREEGRDPGQAG AWIRGEEGREEEKGGGEGRGERGGAAGPGALRP GESRGAGPARRDVAAAATGATLPPPPGRGRGAD PQRHLRRLPDHTPALGRGHQVPGPDSGPGEGYQL PASGL*D*VCVPGGARGGGAQGPQVPGQRLLDR YGHTQPLCESNATLRTARSVHRGTVSHERGLAR GPGLPARGGDGAGGRE*PQGHPAGL*AQAHPPRQ QV*SRPSHQVPI*AALQRPYQDHPYAWLQLCLH AGG*GC*DVEPHCAFLWLQLTSPVKPAAFPHFL PNAPISHTPQPYPRETL*KVGLEEDCYHPADH*G LHFDSGRPGGTSEGGWN*DYFPPEFLLRSSCAR QKPEAPGCPNHRGTFL*D*SPESFL*GVQGASL WEEVRLVPHWVVC*QLVQDLRPFYQLHSG*DD*G GGGPHHN*DCHAESCQYPQHFQHDIPGICGETN QATEKTP*GDRRLPGGTAGL*CHLGLGTGPEQD IWRRRPFWCAPGGLQLQQPDHYRPNLPGNELFVL *GCLWPCGV*CQRLSDGMDAYRAASGWQLQEDW LL*QHQG*SFLVQNR*MDWRVPPS*PDPGHQDI PLPVTETLYLRLSSLQPGHCPSCCLSVL*HLQLT CPLYPELTAQPEQPDCCGLLTGFSCCLPPGARW LPHWEEPVSFRLPGPPLAPGPGL*SGLRFHVHQ DLVGPHGLHKEGRKEGVEEDSGTLEAVCHSGPAG GHGCPHSRHLADRGPSAPDH*DICQGGT*GRY* RLYSAPAGALQLQEDEYMAWHFLWLQGAAAAAG NLPCL*DQECVH*EDQ*SPGCGHGYLQCGSPVPH HCSCHHDSVQPAGCSLCLCLSCHSFLLLYHSCC ALCAQDAQADHPRGMAVGGAGHHEDRVIDQQQR GGEVPAVGEGEP*TGKDHC*ERGACL*TAPSTPV SAAAPLPAPPTDTPRTLWGPAQGTP*APRPA*L *WESSAFAL*VRVG*GRTGQ*GEGKGEGKGRGL RKQGVPIPSWEEHAIQSHLL*IHVPL*VLG*FGS LIPLGNRPFSLLLLHVILYHLFTI*FVPGLKLL TAHTLPPQQPHCIFLFPCNTLF*LPRQPLQLLC LCALFLSSRGLPTSALSTPKGPLLFSTVIISFHL TCPSILSHMWLPLNFASFGSSFFSPRLTCSLPL LCALTLSTHASSPLLRVPTEHAHVYTRFSRMLS SCSVTCALGCPAFTATCAPLMVMGLPLSVFG*AC AICLAC*VMSFLFAHVHVYPCTFPVYPPCTLCT FFP*IMVFF*QSHMYPTLHIVMHFSPIHVWWGH PHPLLVTESPFLLRFPPSPLHSCTTLSLHSQSSS PKTAPFCFVFF*GELRKNKWGQVWRAASSG*LM RILTKGRHP*LLG*TDGPMGWEVVSLSHCGVSW GRISPNLNKPVNSVTR

Sequence NM_001470

CGCTCCCCGCTCCCGTGGCTGCCGCCGCCCCGGGGAAGAAGAGACAGGGGTGGGGTTTGGGGGAAGCGAGAGAGGAGGGGAGAGACCCTGGCCAGGCTGG AGCCTGGATTCGAGGGGAGGAGGGACGGGAGGAGGAGAAAGGTGGAGGAGAAGGGAGGGGGGAGCGGGGAGGAGCGGCCGGGCCTGGGGCCTTGAGGCCC GGGGAGAGCCGGGGAGCCGGGCCCGCGCGCCGAGATGTTGCTGCTGCTGCTACTGGCGCCACTCTTCCTCCGCCCCCCGGGCGCGGGCGGGGCGCAGACC CCCAACGCCACCTCAGAAGGTTGCCAGATCATACACCCGCCCTGGGAAGGGGGCATCAGGTACCGGGGCCTGACTCGGGACCAGGTGAAGGCTATCAACT TCCTGCCAGTGGACTATGAGATTGAGTATGTGTGCCGGGGGGAGCGCGAGGTGGTGGGGCCCAAGGTCCGCAAGTGCCTGGCCAACGGCTCCTGGACAGA TATGGACACACCCAGCCGCTGTGTCCGAATCTGCTCCAAGTCTTATTTGACCCTGGAAAATGGGAAGGTTTTCCTGACGGGTGGGGACCTCCCAGCTCTG GACGGAGCCCGGGTGGATTTCCGGTGTGACCCCGACTTCCATCTGGTGGGCAGCTCCCGGAGCATCTGTAGTCAGGGCCAGTGGAGCACCCCCAAGCCCC ACTGCCAGGTGAATCGAACGCCACACTCAGAACGGCGCGCAGTGTACATCGGGGCACTGTTTCCCATGAGCGGGGGCTGGCCAGGGGGCCAGGCCTGCCA GCCCGCGGTGGAGATGGCGCTGGAGGACGTGAATAGCCGCAGGGACATCCTGCCGGACTATGAGCTCAAGCTCATCCACCACGACAGCAAGTGTGATCCA GGCCAAGCCACCAAGTACCTATATGAGCTGCTCTACAACGACCCTATCAAGATCATCCTTATGCCTGGCTGCAGCTCTGTCTCCACGCTGGTGGCTGAGG CTGCTAGGATGTGGAACCTCATTGTGCTTTCCTATGGCTCCAGCTCACCAGCCCTGTCAAACCGGCAGCGTTTCCCCACTTTCTTCCGAACGCACCCATC AGCCACACTCCACAACCCTACCCGCGTGAAACTCTTTGAAAAGTGGGGCTGGAAGAAGATTGCTACCATCCAGCAGACCACTGAGGTCTTCACTTCGACT CTGGACGACCTGGAGGAACGAGTGAAGGAGGCTGGAATTGAGATTACTTTCCGCCAGAGTTTCTTCTCAGATCCAGCTGTGCCCGTCAAAAACCTGAAGC GCCAGGATGCCCGAATCATCGTGGGACTTTTCTATGAGACTGAAGCCCGGAAAGTTTTTTGTGAGGTGTACAAGGAGCGTCTCTTTGGGAAGAAGTACGT CTGGTTCCTCATTGGGTGGTATGCTGACAATTGGTTCAAGATCTACGACCCTTCTATCAACTGCACAGTGGATGAGATGACTGAGGCGGTGGAGGGCCAC ATCACAACTGAGATTGTCATGCTGAATCCTGCCAATACCCGCAGCATTTCCAACATGACATCCCAGGAATTTGTGGAGAAACTAACCAAGCGACTGAAAA GACACCCTGAGGAGACAGGAGGCTTCCAGGAGGCACCGCTGGCCTATGATGCCATCTGGGCCTTGGCACTGGCCCTGAACAAGACATCTGGAGGAGGCGG CCGTTCTGGTGTGCGCCTGGAGGACTTCAACTACAACAACCAGACCATTACCGACCAAATCTACCGGGCAATGAACTCTTCGTCCTTTGAGGGTGTCTCT GGCCATGTGGTGTTTGATGCCAGCGGCTCTCGGATGGCATGGACGCTTATCGAGCAGCTTCAGGGTGGCAGCTACAAGAAGATTGGCTACTATGACAGCA CCAAGGATGATCTTTCCTGGTCCAAAACAGATAAATGGATTGGAGGGTCCCCCCCAGCTGACCAGACCCTGGTCATCAAGACATTCCGCTTCCTGTCACA GAAACTCTTTATCTCCGTCTCAGTTCTCTCCAGCCTGGGCATTGTCCTAGCTGTTGTCTGTCTGTCCTTTAACATCTACAACTCACATGTCCGTTATATC CAGAACTCACAGCCCAACCTGAACAACCTGACTGCTGTGGGCTGCTCACTGGCTTTAGCTGCTGTCTTCCCCCTGGGGCTCGATGGTTACCACATTGGGA GGAACCAGTTTCCTTTCGTCTGCCAGGCCCGCCTCTGGCTCCTGGGCCTGGGCTTTAGTCTGGGCTACGGTTCCATGTTCACCAAGATTTGGTGGGTCCA CACGGTCTTCACAAAGAAGGAAGAAAAGAAGGAGTGGAGGAAGACTCTGGAACCCTGGAAGCTGTATGCCACAGTGGGCCTGCTGGTGGGCATGGATGTC CTCACTCTCGCCATCTGGCAGATCGTGGACCCTCTGCACCGGACCATTGAGACATTTGCCAAGGAGGAACCTAAGGAAGATATTGACGTCTCTATTCTGC CCCAGCTGGAGCATTGCAGCTCCAGGAAGATGAATACATGGCTTGGCATTTTCTATGGTTACAAGGGGCTGCTGCTGCTGCTGGGAATCTTCCTTGCTTA TGAGACCAAGAGTGTGTCCACTGAGAAGATCAATGATCACCGGGCTGTGGGCATGGCTATCTACAATGTGGCAGTCCTGTGCCTCATCACTGCTCCTGTC ACCATGATTCTGTCCAGCCAGCAGGATGCAGCCTTTGCCTTTGCCTCTCTTGCCATAGTTTTCTCCTCCTATATCACTCTTGTTGTGCTCTTTGTGCCCA AGATGCGCAGGCTGATCACCCGAGGGGAATGGCAGTCGGAGGCGCAGGACACCATGAAGACAGGGTCATCGACCAACAACAACGAGGAGGAGAAGTCCCG GCTGTTGGAGAAGGAGAACCGTGAACTGGAAAAGATCATTGCTGAGAAAGAGGAGCGTGTCTCTGAACTGCGCCATCAACTCCAGTCTCGGCAGCAGCTC CGCTCCCGGCGCCACCCACCGACACCCCCAGAACCCTCTGGGGGCCTGCCCAGGGGACCCCCTGAGCCCCCCGACCGGCTTAGCTGTGATGGGAGTCGAG TGCATTTGCTTTATAAGTGAGGGTAGGGTGAGGGAGGACAGGCCAGTAGGGGGAGGGAAAGGGAGAGGGGAAGGGCAGGGGACTCAGGAAGCAGGGGGTC CCCATCCCCAGCTGGGAAGAACATGCTATCCAATCTCATCTCTTGTAAATACATGTCCCCCTGTGAGTTCTGGGCTGATTTGGGTCTCTCATACCTCTGG GAAACAGACCTTTTTCTCTCTTACTGCTTCATGTAATTTTGTATCACCTCTTCACAATTTAGTTCGTACCTGGCTTGAAGCTGCTCACTGCTCACACGCT GCCTCCTCAGCAGCCTCACTGCATCTTTCTCTTCCCATGCAACACCCTCTTCTAGTTACCACGGCAACCCCTGCAGCTCCTCTGCCTTTGTGCTCTGTTC CTGTCCAGCAGGGGTCTCCCAACAAGTGCTCTTTCCACCCCAAAGGGGCCTCTCCTTTTCTCCACTGTCATAATCTCTTTCCATCTTACTTGCCCTTCTA TACTTTCTCACATGTGGCTCCCCCTGAATTTTGCTTCCTTTGGGAGCTCATTCTTTTCGCCAAGGCTCACATGCTCCTTGCCTCTGCTCTGTGCACTCAC GCTCAGCACACATGCATCCTCCCCTCTCCTGCGTGTGCCCACTGAACATGCTCATGTGTACACACGCTTTTCCCGTATGCTTTCTTCATGTTCAGTCACA TGTGCTCTCGGGTGCCCTGCATTCACAGCTACGTGTGCCCCTCTCATGGTCATGGGTCTGCCCTTGAGCGTGTTTGGGTAGGCATGTGCAATTTGTCTAG CATGCTGAGTCATGTCTTTCCTATTTGCACACGTCCATGTTTATCCATGTACTTTCCCTGTGTACCCTCCATGTACCTTGTGTACTTTCTTCCCTTAAAT CATGGTATTCTTCTGACAGAGCCATATGTACCCTACCCTGCACATTGTTATGCACTTTTCCCCAATTCATGTTTGGTGGGGCCATCCACACCCTCTCCTT GTCACAGAATCTCCATTTCTGCTCAGATTCCCCCCATCTCCATTGCATTCATGTACTACCCTCAGTCTACACTCACAATCATCTTCTCCCAAGACTGCTC CCTTTTGTTTTGTGTTTTTTTGAGGGGAATTAAGGAAAAATAAGTGGGGGCAGGTTTGGAGAGCTGCTTCCAGTGGATAGTTGATGAGAATCCTGACCAA AGGAAGGCACCCTTGACTGTTGGGATAGACAGATGGACCTATGGGGTGGGAGGTGGTGTCCCTTTCACACTGTGGTGTCTCTTGGGGAAGGATCTCCCCG AATCTCAATAAACCAGTGAACAGTGTGACTCGGCA

refseq_GABBR1.F1 (forward primer)
refseq_GABBR1.R1 (reverse primer)
Single exon skipping

Frame 0

RSPLPWLPPPRGRRDRGGVWGKRERRGETLARL EPGFEGRRDGRRRKVEEKGGGSGEERPGLGP*GP GRAGEPGPRAEMLLLLLLAPLFLRPPGAGGAQT PNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTD MDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL DGARVDFRCDPDFHLVGSSRSICSQGQWSTPKP HCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQ PAVEMALEDVNSRRDILPDYELKLIHHDSKCDP GQATKYLYELLYNDPIKIILMPGCSSVSTLVAE AARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPS ATLHNPTRVKLFEKWGWKKIATIQQTTEVFTST LDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK RQDARIIVGLFYETEARKVFCEVYKERLFGKKYV WFLIGWYADNWFKIYDPSINCTVDEMTEAVEGH ITTEIVMLNPANTRSISNMTSQEFVEKLTKRLK RHPEETGGFQEAPLAYDAIWALALALNKTSGGGG RSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVS GHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDS TKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQ KLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYI QNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIG RNQFPFVCQARLWLLGLGFSLGYGSMFTKIWWVH TVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDV LTLAIWQIVDPLHRTIETFAKEEPKEDIDVSIL PQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAY ETKSVSTEKINDHRAVGMAIYNVAVLCLITAPV TMILSSQQDAAFAFASLAIVFSSYITLVVLFVP KMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSR LLEKENRELEKIIAEKEERVSELRHQLQSRQQL RSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSR VHLLYK*G*GEGGQASRGRERERGRAGDSGSRGS PSPAGKNMLSNLISCKYMSPCEFWADLGLSYLW ETDLFLSYCFM*FCITSSQFSSYLA*SCSLLTR CLLSSLTASFSSHATPSSSYHGNPCSSSAFVLCS CPAGVSQQVLFPPQRGLSFSPLS*SLSILLALL YFLTCGSP*ILLPLGAHSFRQGSHAPCLCSVHS RSAHMHPPLSCVCPLNMLMCTHAFPVCFLHVQSH VLSGALHSQLRVPLSWSWVCP*ACLGRHVQFV* HAESCLSYLHTSMFIHVLSLCTLHVPCVLSSLK SWYSSDRAICTLPCTLLCTFPQFMFGGAIHTLSL SQNLHFCSDSPHLHCIHVLPSVYTHNHLLPRLL PFVLCFFEGN*GKISGGRFGELLPVDS**ES*P KEGTLDCWDRQMDLWGGRWCPFHTVVSLGEGSPR ISINQ*TV*LG

Frame 1

APRSRGCRRPGEEETGVGFGGSERGGERPWPGW SLDSRGGGTGGGERWRRREGGAGRSGRAWGLEA RGEPGSRARAPRCCCCCYWRHSSSAPRARAGRRP PTPPQKVARSYTRPGKGASGTGA*LGTR*RLST SCQWTMRLSMCAGGSARWWGPRSASAWPTAPGQ IWTHPAAVSESAPSLI*PWKMGRFS*RVGTSQLW TEPGWISGVTPTSIWWAAPGASVVRASGAPPSP TAR*IERHTQNGAQCTSGHCFP*AGAGQGARPA SPRWRWRWRT*IAAGTSCRTMSSSSSTTTASVIQ AKPPSTYMSCSTTTLSRSSLCLAAALSPRWWLR LLGCGTSLCFPMAPAHQPCQTGSVSPLSSERTH QPHSTTLPA*NSLKSGAGRRLLPSSRPLRSSLRL WTTWRNE*RRLELRLLSARVSSQIQLCPSKT*S ARMPESSWDFSMRLKPGKFFVRCTRSVSLGRST SGSSLGGMLTIGSRSTTLLSTAQWMR*LRRWRAT SQLRLSC*ILPIPAAFPT*HPRNLWRN*PSD*K DTLRRQEASRRHRWPMMPSGPWHWP*TRHLEEA AVLVCAWRTSTTTTRPLPTKSTGQ*TLRPLRVSL AMWCLMPAALGWHGRLSSSFRVAATRRLATMTA PRMIFPGPKQINGLEGPPQLTRPWSSRHSASCH RNSLSPSQFSPAWALS*LLSVCPLTSTTHMSVIS RTHSPT*TT*LLWAAHWL*LLSSPWGSMVTTLG GTSFLSSARPASGSWAWALVWATVPCSPRFGGS TRSSQRRKKRRSGGRLWNPGSCMPQWACWWAWMS SLSPSGRSWTLCTGPLRHLPRRNLRKILTSLFC PSWSIAAPGR*IHGLAFSMVTRGCCCCWESSLL MRPRVCPLRRSMITGLWAWLSTMWQSCASSLLLS P*FCPASRMQPLPLPLLP*FSPPISLLLCSLCP RCAG*SPEGNGSRRRRTP*RQGHRPTTTRRRSP GCWRRRTVNWKRSLLRKRSVSLNCAINSSLGSSS APGATHRHPQNPLGACPGDPLSPPTGLAVMGVE CICFISEGRVREDRPVGGGKGRGEGQGTQEAGG PHPQLGRTCYPISSLVNTCPPVSSGLIWVSHTSG KQTFFSLTASCNFVSPLHNLVRTWLEAAHCSHA ASSAASLHLSLPMQHPLLVTTATPAAPLPLCSV PVQQGSPNKCSFHPKGASPFLHCHNLFPSYLPFY TFSHVAPPEFCFLWELILFAKAHMLLASALCTH AQHTCILPSPACAH*TCSCVHTLFPYAFFMFSH MCSRVPCIHSYVCPSHGHGSALERVWVGMCNLSS MLSHVFPICTRPCLSMYFPCVPSMYLVYFLPLN HGILLTEPYVPYPAHCYALFPNSCLVGPSTPSP CHRISISAQIPPISIAFMYYPQSTLTIIFSQDCS LLFCVFLRGIKEK*VGAGLESCFQWIVDENPDQ RKAPLTVGIDRWTYGVGGGVPFTLWCLLGKDLP ESQ*TSEQCDSA

Frame 2

LPAPVAAAAPGKKRQGWGLGEAREEGRDPGQAG AWIRGEEGREEEKGGGEGRGERGGAAGPGALRP GESRGAGPARRDVAAAATGATLPPPPGRGRGAD PQRHLRRLPDHTPALGRGHQVPGPDSGPGEGYQL PASGL*D*VCVPGGARGGGAQGPQVPGQRLLDR YGHTQPLCPNLLQVLFDPGKWEGFPDGWGPPSS GRSPGGFPV*PRLPSGGQLPEHL*SGPVEHPQAP LPGESNATLRTARSVHRGTVSHERGLARGPGLP ARGGDGAGGRE*PQGHPAGL*AQAHPPRQQV*S RPSHQVPI*AALQRPYQDHPYAWLQLCLHAGG*G C*DVEPHCAFLWLQLTSPVKPAAFPHFLPNAPI SHTPQPYPRETL*KVGLEEDCYHPADH*GLHFD SGRPGGTSEGGWN*DYFPPEFLLRSSCARQKPEA PGCPNHRGTFL*D*SPESFL*GVQGASLWEEVR LVPHWVVC*QLVQDLRPFYQLHSG*DD*GGGGP HHN*DCHAESCQYPQHFQHDIPGICGETNQATEK TP*GDRRLPGGTAGL*CHLGLGTGPEQDIWRRR PFWCAPGGLQLQQPDHYRPNLPGNELFVL*GCL WPCGV*CQRLSDGMDAYRAASGWQLQEDWLL*QH QG*SFLVQNR*MDWRVPPS*PDPGHQDIPLPVT ETLYLRLSSLQPGHCPSCCLSVL*HLQLTCPLY PELTAQPEQPDCCGLLTGFSCCLPPGARWLPHWE EPVSFRLPGPPLAPGPGL*SGLRFHVHQDLVGP HGLHKEGRKEGVEEDSGTLEAVCHSGPAGGHGC PHSRHLADRGPSAPDH*DICQGGT*GRY*RLYSA PAGALQLQEDEYMAWHFLWLQGAAAAAGNLPCL *DQECVH*EDQ*SPGCGHGYLQCGSPVPHHCSC HHDSVQPAGCSLCLCLSCHSFLLLYHSCCALCAQ DAQADHPRGMAVGGAGHHEDRVIDQQQRGGEVP AVGEGEP*TGKDHC*ERGACL*TAPSTPVSAAA PLPAPPTDTPRTLWGPAQGTP*APRPA*L*WESS AFAL*VRVG*GRTGQ*GEGKGEGKGRGLRKQGV PIPSWEEHAIQSHLL*IHVPL*VLG*FGSLIPL GNRPFSLLLLHVILYHLFTI*FVPGLKLLTAHTL PPQQPHCIFLFPCNTLF*LPRQPLQLLCLCALF LSSRGLPTSALSTPKGPLLFSTVIISFHLTCPS ILSHMWLPLNFASFGSSFFSPRLTCSLPLLCALT LSTHASSPLLRVPTEHAHVYTRFSRMLSSCSVT CALGCPAFTATCAPLMVMGLPLSVFG*ACAICL AC*VMSFLFAHVHVYPCTFPVYPPCTLCTFFP*I MVFF*QSHMYPTLHIVMHFSPIHVWWGHPHPLL VTESPFLLRFPPSPLHSCTTLSLHSQSSSPKTA PFCFVFF*GELRKNKWGQVWRAASSG*LMRILTK GRHP*LLG*TDGPMGWEVVSLSHCGVSWGRISP NLNKPVNSVTR

Sequence NM_021905

CGCTCCCCGCTCCCGTGGCTGCCGCCGCCCCGGGGAAGAAGAGACAGGGGTGGGGTTTGGGGGAAGCGAGAGAGGAGGGGAGAGACCCTGGCCAGGCTGG AGCCTGGATTCGAGGGGAGGAGGGACGGGAGGAGGAGAAAGGTGGAGGAGAAGGGAGGGGGGAGCGGGGAGGAGCGGCCGGGCCTGGGGCCTTGAGGCCC GGGGAGAGCCGGGGAGCCGGGCCCGCGCGCCGAGATGTTGCTGCTGCTGCTACTGGCGCCACTCTTCCTCCGCCCCCCGGGCGCGGGCGGGGCGCAGACC CCCAACGCCACCTCAGAAGGTTGCCAGATCATACACCCGCCCTGGGAAGGGGGCATCAGGTACCGGGGCCTGACTCGGGACCAGGTGAAGGCTATCAACT TCCTGCCAGTGGACTATGAGATTGAGTATGTGTGCCGGGGGGAGCGCGAGGTGGTGGGGCCCAAGGTCCGCAAGTGCCTGGCCAACGGCTCCTGGACAGA TATGGACACACCCAGCCGCTGTGTCCGAATCTGCTCCAAGTCTTATTTGACCCTGGAAAATGGGAAGGTTTTCCTGACGGGTGGGGACCTCCCAGCTCTG GACGGAGCCCGGGTGGATTTCCGGTGTGACCCCGACTTCCATCTGGTGGGCAGCTCCCGGAGCATCTGTAGTCAGGGCCAGTGGAGCACCCCCAAGCCCC ACTGCCAGGTGAATCGAACGCCACACTCAGAACGGCGCGCAGTGTACATCGGGGCACTGTTTCCCATGAGCGGGGGCTGGCCAGGGGGCCAGGCCTGCCA GCCCGCGGTGGAGATGGCGCTGGAGGACGTGAATAGCCGCAGGGACATCCTGCCGGACTATGAGCTCAAGCTCATCCACCACGACAGCAAGTGTGATCCA GGCCAAGCCACCAAGTACCTATATGAGCTGCTCTACAACGACCCTATCAAGATCATCCTTATGCCTGGCTGCAGCTCTGTCTCCACGCTGGTGGCTGAGG CTGCTAGGATGTGGAACCTCATTGTGCTTTCCTATGGCTCCAGCTCACCAGCCCTGTCAAACCGGCAGCGTTTCCCCACTTTCTTCCGAACGCACCCATC AGCCACACTCCACAACCCTACCCGCGTGAAACTCTTTGAAAAGTGGGGCTGGAAGAAGATTGCTACCATCCAGCAGACCACTGAGGTCTTCACTTCGACT CTGGACGACCTGGAGGAACGAGTGAAGGAGGCTGGAATTGAGATTACTTTCCGCCAGAGTTTCTTCTCAGATCCAGCTGTGCCCGTCAAAAACCTGAAGC GCCAGGATGCCCGAATCATCGTGGGACTTTTCTATGAGACTGAAGCCCGGAAAGTTTTTTGTGAGGTGTACAAGGAGCGTCTCTTTGGGAAGAAGTACGT CTGGTTCCTCATTGGGTGGTATGCTGACAATTGGTTCAAGATCTACGACCCTTCTATCAACTGCACAGTGGATGAGATGACTGAGGCGGTGGAGGGCCAC ATCACAACTGAGATTGTCATGCTGAATCCTGCCAATACCCGCAGCATTTCCAACATGACATCCCAGGAATTTGTGGAGAAACTAACCAAGCGACTGAAAA GACACCCTGAGGAGACAGGAGGCTTCCAGGAGGCACCGCTGGCCTATGATGCCATCTGGGCCTTGGCACTGGCCCTGAACAAGACATCTGGAGGAGGCGG CCGTTCTGGTGTGCGCCTGGAGGACTTCAACTACAACAACCAGACCATTACCGACCAAATCTACCGGGCAATGAACTCTTCGTCCTTTGAGGGTGTCTCT GGCCATGTGGTGTTTGATGCCAGCGGCTCTCGGATGGCATGGACGCTTATCGAGCAGCTTCAGGGTGGCAGCTACAAGAAGATTGGCTACTATGACAGCA CCAAGGATGATCTTTCCTGGTCCAAAACAGATAAATGGATTGTTATATCCAGAACTCACAGCCCAACCTGAACAACCTGACTGCTGTGGGCTGCTCACTG GCTTTAGCTGCTGTCTTCCCCCTGGGGCTCGATGGTTACCACATTGGGAGGAACCAGTTTCCTTTCGTCTGCCAGGCCCGCCTCTGGCTCCTGGGCCTGG GCTTTAGTCTGGGCTACGGTTCCATGTTCACCAAGATTTGGTGGGTCCACACGGTCTTCACAAAGAAGGAAGAAAAGAAGGAGTGGAGGAAGACTCTGGA ACCCTGGAAGCTGTATGCCACAGTGGGCCTGCTGGTGGGCATGGATGTCCTCACTCTCGCCATCTGGCAGATCGTGGACCCTCTGCACCGGACCATTGAG ACATTTGCCAAGGAGGAACCTAAGGAAGATATTGACGTCTCTATTCTGCCCCAGCTGGAGCATTGCAGCTCCAGGAAGATGAATACATGGCTTGGCATTT TCTATGGTTACAAGGGGCTGCTGCTGCTGCTGGGAATCTTCCTTGCTTATGAGACCAAGAGTGTGTCCACTGAGAAGATCAATGATCACCGGGCTGTGGG CATGGCTATCTACAATGTGGCAGTCCTGTGCCTCATCACTGCTCCTGTCACCATGATTCTGTCCAGCCAGCAGGATGCAGCCTTTGCCTTTGCCTCTCTT GCCATAGTTTTCTCCTCCTATATCACTCTTGTTGTGCTCTTTGTGCCCAAGATGCGCAGGCTGATCACCCGAGGGGAATGGCAGTCGGAGGCGCAGGACA CCATGAAGACAGGGTCATCGACCAACAACAACGAGGAGGAGAAGTCCCGGCTGTTGGAGAAGGAGAACCGTGAACTGGAAAAGATCATTGCTGAGAAAGA GGAGCGTGTCTCTGAACTGCGCCATCAACTCCAGTCTCGGCAGCAGCTCCGCTCCCGGCGCCACCCACCGACACCCCCAGAACCCTCTGGGGGCCTGCCC AGGGGACCCCCTGAGCCCCCCGACCGGCTTAGCTGTGATGGGAGTCGAGTGCATTTGCTTTATAAGTGAGGGTAGGGTGAGGGAGGACAGGCCAGTAGGG GGAGGGAAAGGGAGAGGGGAAGGGCAGGGGACTCAGGAAGCAGGGGGTCCCCATCCCCAGCTGGGAAGAACATGCTATCCAATCTCATCTCTTGTAAATA CATGTCCCCCTGTGAGTTCTGGGCTGATTTGGGTCTCTCATACCTCTGGGAAACAGACCTTTTTCTCTCTTACTGCTTCATGTAATTTTGTATCACCTCT TCACAATTTAGTTCGTACCTGGCTTGAAGCTGCTCACTGCTCACACGCTGCCTCCTCAGCAGCCTCACTGCATCTTTCTCTTCCCATGCAACACCCTCTT CTAGTTACCACGGCAACCCCTGCAGCTCCTCTGCCTTTGTGCTCTGTTCCTGTCCAGCAGGGGTCTCCCAACAAGTGCTCTTTCCACCCCAAAGGGGCCT CTCCTTTTCTCCACTGTCATAATCTCTTTCCATCTTACTTGCCCTTCTATACTTTCTCACATGTGGCTCCCCCTGAATTTTGCTTCCTTTGGGAGCTCAT TCTTTTCGCCAAGGCTCACATGCTCCTTGCCTCTGCTCTGTGCACTCACGCTCAGCACACATGCATCCTCCCCTCTCCTGCGTGTGCCCACTGAACATGC TCATGTGTACACACGCTTTTCCCGTATGCTTTCTTCATGTTCAGTCACATGTGCTCTCGGGTGCCCTGCATTCACAGCTACGTGTGCCCCTCTCATGGTC ATGGGTCTGCCCTTGAGCGTGTTTGGGTAGGCATGTGCAATTTGTCTAGCATGCTGAGTCATGTCTTTCCTATTTGCACACGTCCATGTTTATCCATGTA CTTTCCCTGTGTACCCTCCATGTACCTTGTGTACTTTCTTCCCTTAAATCATGGTATTCTTCTGACAGAGCCATATGTACCCTACCCTGCACATTGTTAT GCACTTTTCCCCAATTCATGTTTGGTGGGGCCATCCACACCCTCTCCTTGTCACAGAATCTCCATTTCTGCTCAGATTCCCCCCATCTCCATTGCATTCA TGTACTACCCTCAGTCTACACTCACAATCATCTTCTCCCAAGACTGCTCCCTTTTGTTTTGTGTTTTTTTGAGGGGAATTAAGGAAAAATAAGTGGGGGC AGGTTTGGAGAGCTGCTTCCAGTGGATAGTTGATGAGAATCCTGACCAAAGGAAGGCACCCTTGACTGTTGGGATAGACAGATGGACCTATGGGGTGGGA GGTGGTGTCCCTTTCACACTGTGGTGTCTCTTGGGGAAGGATCTCCCCGAATCTCAATAAACCAGTGAACAGTGTGACTCGGCA

refseq_GABBR1.F1 (forward primer)
refseq_GABBR1.R1 (reverse primer)
Single exon skipping

Frame 0

RSPLPWLPPPRGRRDRGGVWGKRERRGETLARL EPGFEGRRDGRRRKVEEKGGGSGEERPGLGP*GP GRAGEPGPRAEMLLLLLLAPLFLRPPGAGGAQT PNATSEGCQIIHPPWEGGIRYRGLTRDQVKAIN FLPVDYEIEYVCRGEREVVGPKVRKCLANGSWTD MDTPSRCVRICSKSYLTLENGKVFLTGGDLPAL DGARVDFRCDPDFHLVGSSRSICSQGQWSTPKP HCQVNRTPHSERRAVYIGALFPMSGGWPGGQACQ PAVEMALEDVNSRRDILPDYELKLIHHDSKCDP GQATKYLYELLYNDPIKIILMPGCSSVSTLVAE AARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPS ATLHNPTRVKLFEKWGWKKIATIQQTTEVFTST LDDLEERVKEAGIEITFRQSFFSDPAVPVKNLK RQDARIIVGLFYETEARKVFCEVYKERLFGKKYV WFLIGWYADNWFKIYDPSINCTVDEMTEAVEGH ITTEIVMLNPANTRSISNMTSQEFVEKLTKRLK RHPEETGGFQEAPLAYDAIWALALALNKTSGGGG RSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVS GHVVFDASGSRMAWTLIEQLQGGSYKKIGYYDS TKDDLSWSKTDKWIVISRTHSPT*TT*LLWAAHW L*LLSSPWGSMVTTLGGTSFLSSARPASGSWAW ALVWATVPCSPRFGGSTRSSQRRKKRRSGGRLW NPGSCMPQWACWWAWMSSLSPSGRSWTLCTGPLR HLPRRNLRKILTSLFCPSWSIAAPGR*IHGLAF SMVTRGCCCCWESSLLMRPRVCPLRRSMITGLW AWLSTMWQSCASSLLLSP*FCPASRMQPLPLPLL P*FSPPISLLLCSLCPRCAG*SPEGNGSRRRRT P*RQGHRPTTTRRRSPGCWRRRTVNWKRSLLRK RSVSLNCAINSSLGSSSAPGATHRHPQNPLGACP GDPLSPPTGLAVMGVECICFISEGRVREDRPVG GGKGRGEGQGTQEAGGPHPQLGRTCYPISSLVN TCPPVSSGLIWVSHTSGKQTFFSLTASCNFVSPL HNLVRTWLEAAHCSHAASSAASLHLSLPMQHPL LVTTATPAAPLPLCSVPVQQGSPNKCSFHPKGA SPFLHCHNLFPSYLPFYTFSHVAPPEFCFLWELI LFAKAHMLLASALCTHAQHTCILPSPACAH*TC SCVHTLFPYAFFMFSHMCSRVPCIHSYVCPSHG HGSALERVWVGMCNLSSMLSHVFPICTRPCLSMY FPCVPSMYLVYFLPLNHGILLTEPYVPYPAHCY ALFPNSCLVGPSTPSPCHRISISAQIPPISIAF MYYPQSTLTIIFSQDCSLLFCVFLRGIKEK*VGA GLESCFQWIVDENPDQRKAPLTVGIDRWTYGVG GGVPFTLWCLLGKDLPESQ*TSEQCDSA

Frame 1

APRSRGCRRPGEEETGVGFGGSERGGERPWPGW SLDSRGGGTGGGERWRRREGGAGRSGRAWGLEA RGEPGSRARAPRCCCCCYWRHSSSAPRARAGRRP PTPPQKVARSYTRPGKGASGTGA*LGTR*RLST SCQWTMRLSMCAGGSARWWGPRSASAWPTAPGQ IWTHPAAVSESAPSLI*PWKMGRFS*RVGTSQLW TEPGWISGVTPTSIWWAAPGASVVRASGAPPSP TAR*IERHTQNGAQCTSGHCFP*AGAGQGARPA SPRWRWRWRT*IAAGTSCRTMSSSSSTTTASVIQ AKPPSTYMSCSTTTLSRSSLCLAAALSPRWWLR LLGCGTSLCFPMAPAHQPCQTGSVSPLSSERTH QPHSTTLPA*NSLKSGAGRRLLPSSRPLRSSLRL WTTWRNE*RRLELRLLSARVSSQIQLCPSKT*S ARMPESSWDFSMRLKPGKFFVRCTRSVSLGRST SGSSLGGMLTIGSRSTTLLSTAQWMR*LRRWRAT SQLRLSC*ILPIPAAFPT*HPRNLWRN*PSD*K DTLRRQEASRRHRWPMMPSGPWHWP*TRHLEEA AVLVCAWRTSTTTTRPLPTKSTGQ*TLRPLRVSL AMWCLMPAALGWHGRLSSSFRVAATRRLATMTA PRMIFPGPKQINGLLYPELTAQPEQPDCCGLLT GFSCCLPPGARWLPHWEEPVSFRLPGPPLAPGPG L*SGLRFHVHQDLVGPHGLHKEGRKEGVEEDSG TLEAVCHSGPAGGHGCPHSRHLADRGPSAPDH* DICQGGT*GRY*RLYSAPAGALQLQEDEYMAWHF LWLQGAAAAAGNLPCL*DQECVH*EDQ*SPGCG HGYLQCGSPVPHHCSCHHDSVQPAGCSLCLCLS CHSFLLLYHSCCALCAQDAQADHPRGMAVGGAGH HEDRVIDQQQRGGEVPAVGEGEP*TGKDHC*ER GACL*TAPSTPVSAAAPLPAPPTDTPRTLWGPA QGTP*APRPA*L*WESSAFAL*VRVG*GRTGQ*G EGKGEGKGRGLRKQGVPIPSWEEHAIQSHLL*I HVPL*VLG*FGSLIPLGNRPFSLLLLHVILYHL FTI*FVPGLKLLTAHTLPPQQPHCIFLFPCNTLF *LPRQPLQLLCLCALFLSSRGLPTSALSTPKGP LLFSTVIISFHLTCPSILSHMWLPLNFASFGSS FFSPRLTCSLPLLCALTLSTHASSPLLRVPTEHA HVYTRFSRMLSSCSVTCALGCPAFTATCAPLMV MGLPLSVFG*ACAICLAC*VMSFLFAHVHVYPC TFPVYPPCTLCTFFP*IMVFF*QSHMYPTLHIVM HFSPIHVWWGHPHPLLVTESPFLLRFPPSPLHS CTTLSLHSQSSSPKTAPFCFVFF*GELRKNKWG QVWRAASSG*LMRILTKGRHP*LLG*TDGPMGWE VVSLSHCGVSWGRISPNLNKPVNSVTR

Frame 2

LPAPVAAAAPGKKRQGWGLGEAREEGRDPGQAG AWIRGEEGREEEKGGGEGRGERGGAAGPGALRP GESRGAGPARRDVAAAATGATLPPPPGRGRGAD PQRHLRRLPDHTPALGRGHQVPGPDSGPGEGYQL PASGL*D*VCVPGGARGGGAQGPQVPGQRLLDR YGHTQPLCPNLLQVLFDPGKWEGFPDGWGPPSS GRSPGGFPV*PRLPSGGQLPEHL*SGPVEHPQAP LPGESNATLRTARSVHRGTVSHERGLARGPGLP ARGGDGAGGRE*PQGHPAGL*AQAHPPRQQV*S RPSHQVPI*AALQRPYQDHPYAWLQLCLHAGG*G C*DVEPHCAFLWLQLTSPVKPAAFPHFLPNAPI SHTPQPYPRETL*KVGLEEDCYHPADH*GLHFD SGRPGGTSEGGWN*DYFPPEFLLRSSCARQKPEA PGCPNHRGTFL*D*SPESFL*GVQGASLWEEVR LVPHWVVC*QLVQDLRPFYQLHSG*DD*GGGGP HHN*DCHAESCQYPQHFQHDIPGICGETNQATEK TP*GDRRLPGGTAGL*CHLGLGTGPEQDIWRRR PFWCAPGGLQLQQPDHYRPNLPGNELFVL*GCL WPCGV*CQRLSDGMDAYRAASGWQLQEDWLL*QH QG*SFLVQNR*MDCYIQNSQPNLNNLTAVGCSL ALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGL GFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLE PWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIE TFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGI FYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVG MAIYNVAVLCLITAPVTMILSSQQDAAFAFASL AIVFSSYITLVVLFVPKMRRLITRGEWQSEAQD TMKTGSSTNNNEEEKSRLLEKENRELEKIIAEKE ERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLP RGPPEPPDRLSCDGSRVHLLYK*G*GEGGQASR GRERERGRAGDSGSRGSPSPAGKNMLSNLISCKY MSPCEFWADLGLSYLWETDLFLSYCFM*FCITS SQFSSYLA*SCSLLTRCLLSSLTASFSSHATPS SSYHGNPCSSSAFVLCSCPAGVSQQVLFPPQRGL SFSPLS*SLSILLALLYFLTCGSP*ILLPLGAH SFRQGSHAPCLCSVHSRSAHMHPPLSCVCPLNM LMCTHAFPVCFLHVQSHVLSGALHSQLRVPLSWS WVCP*ACLGRHVQFV*HAESCLSYLHTSMFIHV LSLCTLHVPCVLSSLKSWYSSDRAICTLPCTLL CTFPQFMFGGAIHTLSLSQNLHFCSDSPHLHCIH VLPSVYTHNHLLPRLLPFVLCFFEGN*GKISGG RFGELLPVDS**ES*PKEGTLDCWDRQMDLWGG RWCPFHTVVSLGEGSPRISINQ*TV*LG