Back to Rnomics Platform
 Open Session
×
1 warning:
  • Access restricted to public data.
    Please sign in at Rnomics Platform to access your data.
Navigation
Home
Sequences

Sequence NM_001013438

CAGCGGCCTTTGCGGTTCCAACATGGCGGAGCTGACGGTGGAGGTTCGCGGCTCTAACGGGGCTTTCTACAAGGGATTTATCAAAGATGTTCATGAAGAC
TCCCTTACAGTTGTTTTTGAAAATAATTGGCAACCAGAACGCCAGGTTCCATTTAATGAAGTTAGATTACCACCACCACCTGATATAAAAAAAGAAATTA
GTGAAGGAGATGAAGTAGAGGTATATTCAAGAGCAAATGACCAAGAGCCATGTGGGTGGTGGTTGGCTAAAGTTCGGATGATGAAAGGAGAATTTTATGT
CATTGAATATGCTGCTTGTGACGCTACTTACAATGAAATAGTCACATTTGAACGACTTCGGCCTGTCAATCAAAATAAAACTGTCAAAAAAAATACCTTC
TTTAAATGCACAGTGGATGTTCCTGAGGATTTGAGAGAGGCGTGTGCTAATGAAAATGCACATAAAGATTTTAAGAAAGCAGTAGGAGCATGCAGAATTT
TTTACCATCCAGAAACAACACAGCTAATGATACTGTCTGCCAGTGAAGCAACTGTGAAGAGAGTAAACATCTTAAGTGACATGCATTTGCGAAGTATTCG
TACGAAGTTGATGCTTATGTCCAGAAATGAAGAGGCCACTAAGCATTTAGAATGCACAAAACAACTTGCAGCAGCTTTTCATGAGGAATTTGTTGTGAGA
GAAGATTTAATGGGCCTGGCAATAGGAACACATGGTAGTAACATCCAGCAAGCTAGGAAGGTTCCTGGAGTTACCGCCATTGAGCTAGATGAAGATACTG
GAACATTCAGAATCTACGGAGAGAGTGCTGATGCTGTAAAAAAGGCTAGAGGTTTCTTGGAATTTGTGGAGGATTTTATTCAGGTTCCTAGGAATCTCGT
TGGAAAAGTAATTGGAAAAAATGGCAAAGTTATTCAAGAAATAGTGGACAAATCTGGTGTGGTTCGAGTGAGAATTGAAGGGGACAATGAAAATAAATTA
CCCAGAGAAGACGGTATGGTTCCATTTGTATTTGTTGGCACTAAAGAAAGCATTGGAAATGTGCAGGTTCTTCTAGAGTATCATATTGCCTATCTAAAGG
AAGTAGAACAGCTAAGAATGGAACGCCTACAGATTGATGAACAGCTGCGACAGATTGGTTCTAGGTCTTATAGCGGAAGAGGCAGAGGTCGTCGGGGACC
TAATTACACCTCCGGTTATGGTACAAATTCTGAGCTGTCTAACCCCTCTGAAACGGAATCTGAGCGTAAAGACGAGCTGAGTGATTGGTCATTGGCAGGA
GAAGATGATCGAGACAGCCGACATCAGCGTGACAGCAGGAGACGCCCAGGAGGAAGAGGCAGAAGTGTTTCAGGGGGTCGAGGTCGTGGTGGACCACGTG
GTGGCAAATCCTCCATCAGTTCTGTGCTCAAAGATCCAGACAGCAATCCATACAGCTTACTTGATAATACAGAATCAGATCAGACTGCAGACACTGATGC
CAGCGAATCTCATCACAGTACTAACCGTCGTAGGCGGTCTCGTAGACGAAGGACTGATGAAGATGCTGTTCTGATGGATGGAATGACTGAATCTGATACA
GCTTCAGTTAATGAAAATGGGCTAGGCAAAAGATGTGATTGAAGAGCATGGTCCTTCAGAAAAGGCAATAAACGGCCCAACTAGTGCTTCTGGCGATGAC
ATTTCTAAGCTACAGCGTACTCCAGGAGAAGAAAAGATTAATACCTTAAAAGAAGAAAACACTCAAGAAGCAGCAGTCCTGAATGGTGTTTCATAAACTG
AAGAAGTTCCTAGTTTACAGTTCTTTTACATTACATTTACAATAGTGCTTGTACAAGCTTGCCAAAGATAGAATATGGATCGCCAGTCTTTACATCGCAC
TTTCAGTTCCTCCATTTGGAATTCAAAAAGGGGAGGGATCCTGAAGAAATCATATGTTAAACATACTTTGACACCTACTGTGTTATAAAATATATCATCA
GATGTGCCTTGAGAATAGTATATGTAACATTAAAAAAAAGTTGCTGGCTATAGGAAATGTTATTTTGTTTTCAAAATATGGCAGAGATGGGGGGTGGTGG
GTGGGGTGGGATCCCTAACGTAATATTCTTTATGAAAGCATTAGCTGCTTTTGTTACATTTTTAATATGCAACCACTTCTTCACCTGAGGAAAACTAGAA
TGAAATGCAGTCTAAAATATTTTGCACTGAATTGTAATTTCTTCATTAGTTTAGTCTGGAAACTGGTCTGTTTTAATGTGTTTTTTAAATGCTGTATGTA
GAGGAAAATCTGCAGACCACTGGAATACATTTGTTAAACTCTCATCTGCAGGGACACTGGGCGATACTTGGCAGTGACTGTTCTACCTTGAGGCTTTGTT
TGGTTTATTTATTAAAGTGTACAGTATTTAAAAATCAAACATAGCTTTAGTTAAAACACTAAGCTGAATTAGTCATGTCCATTCAGACATAACCTGAACT
ACTGAAAAGATCAATTTCCAGAAGGTTTATTCTGTATAAACTACATGTTAGTCTTCAGTAGAGTATCTTTTTTTTTTCCTTTTTTTTTTTTTTATTTCGG
TTGTTTGATGTGCAATATGTTTTTGTATGCAGGTAGTAAATAAACTTTGATCTTCCATTTGCTGAA
  • refseq_FXR1.F3 (forward primer)
  • refseq_FXR1.R3 (reverse primer)
  • Single exon skipping

Frame 0

QRPLRFQHGGADGGGSRL*RGFLQGIYQRCS*R
LPYSCF*K*LATRTPGSI**S*ITTTT*YKKRN*
*RR*SRGIFKSK*PRAMWVVVG*SSDDERRILC
H*ICCL*RYLQ*NSHI*TTSACQSK*NCQKKYL
L*MHSGCS*GFERGVC**KCT*RF*ESSRSMQNF
LPSRNNTANDTVCQ*SNCEESKHLK*HAFAKYS
YEVDAYVQK*RGH*AFRMHKTTCSSFS*GICCE
RRFNGPGNRNTW**HPAS*EGSWSYRH*AR*RYW
NIQNLRREC*CCKKG*RFLGICGGFYSGS*ESR
WKSNWKKWQSYSRNSGQIWCGSSEN*RGQ*K*I
TQRRRYGSICICWH*RKHWKCAGSSRVSYCLSKG
SRTAKNGTPTD**TAATDWF*VL*RKRQRSSGT
*LHLRLWYKF*AV*PL*NGI*A*RRAE*LVIGR
RR*SRQPTSA*QQETPRRKRQKCFRGSRSWWTTW
WQILHQFCAQRSRQQSIQLT**YRIRSDCRH*C
QRISSQY*PS*AVS*TKD**RCCSDGWND*I*Y
SFS**KWARQKM*LKSMVLQKRQ*TAQLVLLAMT
FLSYSVLQEKKRLIP*KKKTLKKQQS*MVFHKL
KKFLVYSSFTLHLQ*CLYKLAKDRIWIASLYIA
LSVPPFGIQKGEGS*RNHMLNIL*HLLCYKIYHQ
MCLENSICNIKKKLLAIGNVILFSKYGRDGGWW
VGWDP*RNILYESISCFCYIFNMQPLLHLRKTR
MKCSLKYFALNCNFFISLVWKLVCFNVFFKCCM*
RKICRPLEYIC*TLICRDTGRYLAVTVLP*GFV
WFIY*SVQYLKIKHSFS*NTKLN*SCPFRHNLN
Y*KDQFPEGLFCINYMLVFSRVSFFFPFFFFYFG
CLMCNMFLYAGSK*TLIFHLL

Frame 1

SGLCGSNMAELTVEVRGSNGAFYKGFIKDVHED
SLTVVFENNWQPERQVPFNEVRLPPPPDIKKEI
SEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYV
IEYAACDATYNEIVTFERLRPVNQNKTVKKNTF
FKCTVDVPEDLREACANENAHKDFKKAVGACRI
FYHPETTQLMILSASEATVKRVNILSDMHLRSIR
TKLMLMSRNEEATKHLECTKQLAAAFHEEFVVR
EDLMGLAIGTHGSNIQQARKVPGVTAIELDEDT
GTFRIYGESADAVKKARGFLEFVEDFIQVPRNLV
GKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL
PREDGMVPFVFVGTKESIGNVQVLLEYHIAYLK
EVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGP
NYTSGYGTNSELSNPSETESERKDELSDWSLAG
EDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPR
GGKSSISSVLKDPDSNPYSLLDNTESDQTADTDA
SESHHSTNRRRRSRRRRTDEDAVLMDGMTESDT
ASVNENGLGKRCD*RAWSFRKGNKRPN*CFWR*
HF*ATAYSRRRKD*YLKRRKHSRSSSPEWCFIN*
RSS*FTVLLHYIYNSACTSLPKIEYGSPVFTSH
FQFLHLEFKKGRDPEEIIC*TYFDTYCVIKYII
RCALRIVYVTLKKSCWL*EMLFCFQNMAEMGGGG
WGGIPNVIFFMKALAAFVTFLICNHFFT*GKLE
*NAV*NILH*IVISSLV*SGNWSVLMCFLNAVC
RGKSADHWNTFVKLSSAGTLGDTWQ*LFYLEALF
GLFIKVYSI*KSNIALVKTLS*ISHVHSDIT*T
TEKINFQKVYSV*TTC*SSVEYLFFFLFFFFIS
VV*CAICFCMQVVNKL*SSIC*

Frame 2

AAFAVPTWRS*RWRFAALTGLSTRDLSKMFMKT
PLQLFLKIIGNQNARFHLMKLDYHHHLI*KKKL
VKEMK*RYIQEQMTKSHVGGGWLKFG**KENFM
SLNMLLVTLLTMK*SHLNDFGLSIKIKLSKKIPS
LNAQWMFLRI*ERRVLMKMHIKILRKQ*EHAEF
FTIQKQHS**YCLPVKQL*RE*TS*VTCICEVF
VRS*CLCPEMKRPLSI*NAQNNLQQLFMRNLL*E
KI*WAWQ*EHMVVTSSKLGRFLELPPLS*MKIL
EHSESTERVLML*KRLEVSWNLWRILFRFLGIS
LEK*LEKMAKLFKK*WTNLVWFE*ELKGTMKINY
PEKTVWFHLYLLALKKALEMCRFF*SIILPI*R
K*NS*EWNAYRLMNSCDRLVLGLIAEEAEVVGD
LITPPVMVQILSCLTPLKRNLSVKTS*VIGHWQE
KMIETADISVTAGDAQEEEAEVFQGVEVVVDHV
VANPPSVLCSKIQTAIHTAYLIIQNQIRLQTLM
PANLITVLTVVGGLVDEGLMKMLF*WME*LNLIQ
LQLMKMG*AKDVIEEHGPSEKAINGPTSASGDD
ISKLQRTPGEEKINTLKEENTQEAAVLNGVS*T
EEVPSLQFFYITFTIVLVQACQR*NMDRQSLHRT
FSSSIWNSKRGGILKKSYVKHTLTPTVL*NISS
DVP*E*YM*H*KKVAGYRKCYFVFKIWQRWGVV
GGVGSLT*YSL*KH*LLLLHF*YATTSSPEEN*N
EMQSKIFCTEL*FLH*FSLETGLF*CVF*MLYV
EENLQTTGIHLLNSHLQGHWAILGSDCSTLRLC
LVYLLKCTVFKNQT*L*LKH*AELVMSIQT*PEL
LKRSISRRFILYKLHVSLQ*SIFFFSFFFFLFR
LFDVQYVFVCR**INFDLPFAE

Sequence NM_001013439

CAGCGGCCTTTGCGGTTCCAACATGGCGGAGCTGACGGTGGAGGTTCGCGGCTCTAACGGGGCTTTCTACAAGTCAATTCACAATGAATCAAATGTCCCC
ATTTTGGAACTCTGAAGTATTTATAATTGATCTCTATACATATCTACAATCTACTGCTTGTTTCTACTTAGACTTTGACTCCATTACTCATTTTGCCTCA
CAAAGTGAGTTGGTACTTTGACAAAGGTTGGAAAGGACACTAGCCACCTGTGTGTGCACTGAAATCATGTACGCTTGAACATTTGGAATTTTATGTCCAG
CCATAATCCACTTGCATATGCACTTTGTGGAAACTGTGGTCTTCAGAACTCTGGAAGAATGAGAATGGCGGAGTGGAAAAGAGTCCTGGATTTGAAGTAA
ACAGATGAGAATTCTAGGGATTTATCAAAGATGTTCATGAAGACTCCCTTACAGTTGTTTTTGAAAATAATTGGCAACCAGAACGCCAGGTTCCATTTAA
TGAAGTTAGATTACCACCACCACCTGATATAAAAAAAGAAATTAGTGAAGGAGATGAAGTAGAGGTATATTCAAGAGCAAATGACCAAGAGCCATGTGGG
TGGTGGTTGGCTAAAGTTCGGATGATGAAAGGAGAATTTTATGTCATTGAATATGCTGCTTGTGACGCTACTTACAATGAAATAGTCACATTTGAACGAC
TTCGGCCTGTCAATCAAAATAAAACTGTCAAAAAAAATACCTTCTTTAAATGCACAGTGGATGTTCCTGAGGATTTGAGAGAGGCGTGTGCTAATGAAAA
TGCACATAAAGATTTTAAGAAAGCAGTAGGAGCATGCAGAATTTTTTACCATCCAGAAACAACACAGCTAATGATACTGTCTGCCAGTGAAGCAACTGTG
AAGAGAGTAAACATCTTAAGTGACATGCATTTGCGAAGTATTCGTACGAAGTTGATGCTTATGTCCAGAAATGAAGAGGCCACTAAGCATTTAGAATGCA
CAAAACAACTTGCAGCAGCTTTTCATGAGGAATTTGTTGTGAGAGAAGATTTAATGGGCCTGGCAATAGGAACACATGGTAGTAACATCCAGCAAGCTAG
GAAGGTTCCTGGAGTTACCGCCATTGAGCTAGATGAAGATACTGGAACATTCAGAATCTACGGAGAGAGTGCTGATGCTGTAAAAAAGGCTAGAGGTTTC
TTGGAATTTGTGGAGGATTTTATTCAGGTTCCTAGGAATCTCGTTGGAAAAGTAATTGGAAAAAATGGCAAAGTTATTCAAGAAATAGTGGACAAATCTG
GTGTGGTTCGAGTGAGAATTGAAGGGGACAATGAAAATAAATTACCCAGAGAAGACGGTATGGTTCCATTTGTATTTGTTGGCACTAAAGAAAGCATTGG
AAATGTGCAGGTTCTTCTAGAGTATCATATTGCCTATCTAAAGGAAGTAGAACAGCTAAGAATGGAACGCCTACAGATTGATGAACAGCTGCGACAGATT
GGTTCTAGGTCTTATAGCGGAAGAGGCAGAGGTCGTCGGGGACCTAATTACACCTCCGGTTATGGTACAAATTCTGAGCTGTCTAACCCCTCTGAAACGG
AATCTGAGCGTAAAGACGAGCTGAGTGATTGGTCATTGGCAGGAGAAGATGATCGAGACAGCCGACATCAGCGTGACAGCAGGAGACGCCCAGGAGGAAG
AGGCAGAAGTGTTTCAGGGGGTCGAGGTCGTGGTGGACCACGTGGTGGCAAATCCTCCATCAGTTCTGTGCTCAAAGATCCAGACAGCAATCCATACAGC
TTACTTGATAATACAGAATCAGATCAGACTGCAGACACTGATGCCAGCGAATCTCATCACAGTACTAACCGTCGTAGGCGGTCTCGTAGACGAAGGACTG
ATGAAGATGCTGTTCTGATGGATGGAATGACTGAATCTGATACAGCTTCAGTTAATGAAAATGGGCTAGTCACAGTTGCAGATTATATTTCTAGAGCTGA
GTCTCAGAGCAGACAAAGAAACCTCCCAAGGGAAACTTTGGCTAAAAACAAGAAAGAAATGGCAAAAGATGTGATTGAAGAGCATGGTCCTTCAGAAAAG
GCAATAAACGGCCCAACTAGTGCTTCTGGCGATGACATTTCTAAGCTACAGCGTACTCCAGGAGAAGAAAAGATTAATACCTTAAAAGAAGAAAACACTC
AAGAAGCAGCAGTCCTGAATGGTGTTTCATAAACTGAAGAAGTTCCTAGTTTACAGTTCTTTTACATTACATTTACAATAGTGCTTGTACAAGCTTGCCA
AAGATAGAATATGGATCGCCAGTCTTTACATCGCACTTTCAGTTCCTCCATTTGGAATTCAAAAAGGGGAGGGATCCTGAAGAAATCATATGTTAAACAT
ACTTTGACACCTACTGTGTTATAAAATATATCATCAGATGTGCCTTGAGAATAGTATATGTAACATTAAAAAAAAGTTGCTGGCTATAGGAAATGTTATT
TTGTTTTCAAAATATGGCAGAGATGGGGGGTGGTGGGTGGGGTGGGATCCCTAACGTAATATTCTTTATGAAAGCATTAGCTGCTTTTGTTACATTTTTA
ATATGCAACCACTTCTTCACCTGAGGAAAACTAGAATGAAATGCAGTCTAAAATATTTTGCACTGAATTGTAATTTCTTCATTAGTTTAGTCTGGAAACT
GGTCTGTTTTAATGTGTTTTTTAAATGCTGTATGTAGAGGAAAATCTGCAGACCACTGGAATACATTTGTTAAACTCTCATCTGCAGGGACACTGGGCGA
TACTTGGCAGTGACTGTTCTACCTTGAGGCTTTGTTTGGTTTATTTATTAAAGTGTACAGTATTTAAAAATCAAACATAGCTTTAGTTAAAACACTAAGC
TGAATTAGTCATGTCCATTCAGACATAACCTGAACTACTGAAAAGATCAATTTCCAGAAGGTTTATTCTGTATAAACTACATGTTAGTCTTCAGTAGAGT
ATCTTTTTTTTTTCCTTTTTTTTTTTTTTATTTCGGTTGTTTGATGTGCAATATGTTTTTGTATGCAGGTAGTAAATAAACTTTGATCTTCCATTTGCTG
AA
  • refseq_FXR1.F3 (forward primer)
  • refseq_FXR1.R3 (reverse primer)
  • Single exon skipping

Frame 0

QRPLRFQHGGADGGGSRL*RGFLQVNSQ*IKCP
HFGTLKYL*LISIHIYNLLLVST*TLTPLLILPH
KVSWYFDKGWKGH*PPVCALKSCTLEHLEFYVQ
P*STCICTLWKLWSSELWKNENGGVEKSPGFEV
NR*EF*GFIKDVHEDSLTVVFENNWQPERQVPFN
EVRLPPPPDIKKEISEGDEVEVYSRANDQEPCG
WWLAKVRMMKGEFYVIEYAACDATYNEIVTFER
LRPVNQNKTVKKNTFFKCTVDVPEDLREACANEN
AHKDFKKAVGACRIFYHPETTQLMILSASEATV
KRVNILSDMHLRSIRTKLMLMSRNEEATKHLEC
TKQLAAAFHEEFVVREDLMGLAIGTHGSNIQQAR
KVPGVTAIELDEDTGTFRIYGESADAVKKARGF
LEFVEDFIQVPRNLVGKVIGKNGKVIQEIVDKS
GVVRVRIEGDNENKLPREDGMVPFVFVGTKESIG
NVQVLLEYHIAYLKEVEQLRMERLQIDEQLRQI
GSRSYSGRGRGRRGPNYTSGYGTNSELSNPSET
ESERKDELSDWSLAGEDDRDSRHQRDSRRRPGGR
GRSVSGGRGRGGPRGGKSSISSVLKDPDSNPYS
LLDNTESDQTADTDASESHHSTNRRRRSRRRRT
DEDAVLMDGMTESDTASVNENGLVTVADYISRAE
SQSRQRNLPRETLAKNKKEMAKDVIEEHGPSEK
AINGPTSASGDDISKLQRTPGEEKINTLKEENT
QEAAVLNGVS*TEEVPSLQFFYITFTIVLVQACQ
R*NMDRQSLHRTFSSSIWNSKRGGILKKSYVKH
TLTPTVL*NISSDVP*E*YM*H*KKVAGYRKCY
FVFKIWQRWGVVGGVGSLT*YSL*KH*LLLLHF*
YATTSSPEEN*NEMQSKIFCTEL*FLH*FSLET
GLF*CVF*MLYVEENLQTTGIHLLNSHLQGHWA
ILGSDCSTLRLCLVYLLKCTVFKNQT*L*LKH*A
ELVMSIQT*PELLKRSISRRFILYKLHVSLQ*S
IFFFSFFFFLFRLFDVQYVFVCR**INFDLPFA
E

Frame 1

SGLCGSNMAELTVEVRGSNGAFYKSIHNESNVP
ILEL*SIYN*SLYISTIYCLFLLRL*LHYSFCL
TK*VGTLTKVGKDTSHLCVH*NHVRLNIWNFMSS
HNPLAYALCGNCGLQNSGRMRMAEWKRVLDLK*
TDENSRDLSKMFMKTPLQLFLKIIGNQNARFHL
MKLDYHHHLI*KKKLVKEMK*RYIQEQMTKSHVG
GGWLKFG**KENFMSLNMLLVTLLTMK*SHLND
FGLSIKIKLSKKIPSLNAQWMFLRI*ERRVLMK
MHIKILRKQ*EHAEFFTIQKQHS**YCLPVKQL*
RE*TS*VTCICEVFVRS*CLCPEMKRPLSI*NA
QNNLQQLFMRNLL*EKI*WAWQ*EHMVVTSSKL
GRFLELPPLS*MKILEHSESTERVLML*KRLEVS
WNLWRILFRFLGISLEK*LEKMAKLFKK*WTNL
VWFE*ELKGTMKINYPEKTVWFHLYLLALKKAL
EMCRFF*SIILPI*RK*NS*EWNAYRLMNSCDRL
VLGLIAEEAEVVGDLITPPVMVQILSCLTPLKR
NLSVKTS*VIGHWQEKMIETADISVTAGDAQEE
EAEVFQGVEVVVDHVVANPPSVLCSKIQTAIHTA
YLIIQNQIRLQTLMPANLITVLTVVGGLVDEGL
MKMLF*WME*LNLIQLQLMKMG*SQLQIIFLEL
SLRADKETSQGKLWLKTRKKWQKM*LKSMVLQKR
Q*TAQLVLLAMTFLSYSVLQEKKRLIP*KKKTL
KKQQS*MVFHKLKKFLVYSSFTLHLQ*CLYKLA
KDRIWIASLYIALSVPPFGIQKGEGS*RNHMLNI
L*HLLCYKIYHQMCLENSICNIKKKLLAIGNVI
LFSKYGRDGGWWVGWDP*RNILYESISCFCYIF
NMQPLLHLRKTRMKCSLKYFALNCNFFISLVWKL
VCFNVFFKCCM*RKICRPLEYIC*TLICRDTGR
YLAVTVLP*GFVWFIY*SVQYLKIKHSFS*NTK
LN*SCPFRHNLNY*KDQFPEGLFCINYMLVFSRV
SFFFPFFFFYFGCLMCNMFLYAGSK*TLIFHLL

Frame 2

AAFAVPTWRS*RWRFAALTGLSTSQFTMNQMSP
FWNSEVFIIDLYTYLQSTACFYLDFDSITHFAS
QSELVL*QRLERTLATCVCTEIMYA*TFGILCP
AIIHLHMHFVETVVFRTLEE*EWRSGKESWI*SK
QMRILGIYQRCS*RLPYSCF*K*LATRTPGSI*
*S*ITTTT*YKKRN**RR*SRGIFKSK*PRAMW
VVVG*SSDDERRILCH*ICCL*RYLQ*NSHI*TT
SACQSK*NCQKKYLL*MHSGCS*GFERGVC**K
CT*RF*ESSRSMQNFLPSRNNTANDTVCQ*SNC
EESKHLK*HAFAKYSYEVDAYVQK*RGH*AFRMH
KTTCSSFS*GICCERRFNGPGNRNTW**HPAS*
EGSWSYRH*AR*RYWNIQNLRREC*CCKKG*RF
LGICGGFYSGS*ESRWKSNWKKWQSYSRNSGQIW
CGSSEN*RGQ*K*ITQRRRYGSICICWH*RKHW
KCAGSSRVSYCLSKGSRTAKNGTPTD**TAATD
WF*VL*RKRQRSSGT*LHLRLWYKF*AV*PL*NG
I*A*RRAE*LVIGRRR*SRQPTSA*QQETPRRK
RQKCFRGSRSWWTTWWQILHQFCAQRSRQQSIQ
LT**YRIRSDCRH*CQRISSQY*PS*AVS*TKD*
*RCCSDGWND*I*YSFS**KWASHSCRLYF*S*
VSEQTKKPPKGNFG*KQERNGKRCD*RAWSFRK
GNKRPN*CFWR*HF*ATAYSRRRKD*YLKRRKHS
RSSSPEWCFIN*RSS*FTVLLHYIYNSACTSLP
KIEYGSPVFTSHFQFLHLEFKKGRDPEEIIC*T
YFDTYCVIKYIIRCALRIVYVTLKKSCWL*EMLF
CFQNMAEMGGGGWGGIPNVIFFMKALAAFVTFL
ICNHFFT*GKLE*NAV*NILH*IVISSLV*SGN
WSVLMCFLNAVCRGKSADHWNTFVKLSSAGTLGD
TWQ*LFYLEALFGLFIKVYSI*KSNIALVKTLS
*ISHVHSDIT*TTEKINFQKVYSV*TTC*SSVE
YLFFFLFFFFISVV*CAICFCMQVVNKL*SSIC*

Sequence NM_005087

CAGCGGCCTTTGCGGTTCCAACATGGCGGAGCTGACGGTGGAGGTTCGCGGCTCTAACGGGGCTTTCTACAAGGGATTTATCAAAGATGTTCATGAAGAC
TCCCTTACAGTTGTTTTTGAAAATAATTGGCAACCAGAACGCCAGGTTCCATTTAATGAAGTTAGATTACCACCACCACCTGATATAAAAAAAGAAATTA
GTGAAGGAGATGAAGTAGAGGTATATTCAAGAGCAAATGACCAAGAGCCATGTGGGTGGTGGTTGGCTAAAGTTCGGATGATGAAAGGAGAATTTTATGT
CATTGAATATGCTGCTTGTGACGCTACTTACAATGAAATAGTCACATTTGAACGACTTCGGCCTGTCAATCAAAATAAAACTGTCAAAAAAAATACCTTC
TTTAAATGCACAGTGGATGTTCCTGAGGATTTGAGAGAGGCGTGTGCTAATGAAAATGCACATAAAGATTTTAAGAAAGCAGTAGGAGCATGCAGAATTT
TTTACCATCCAGAAACAACACAGCTAATGATACTGTCTGCCAGTGAAGCAACTGTGAAGAGAGTAAACATCTTAAGTGACATGCATTTGCGAAGTATTCG
TACGAAGTTGATGCTTATGTCCAGAAATGAAGAGGCCACTAAGCATTTAGAATGCACAAAACAACTTGCAGCAGCTTTTCATGAGGAATTTGTTGTGAGA
GAAGATTTAATGGGCCTGGCAATAGGAACACATGGTAGTAACATCCAGCAAGCTAGGAAGGTTCCTGGAGTTACCGCCATTGAGCTAGATGAAGATACTG
GAACATTCAGAATCTACGGAGAGAGTGCTGATGCTGTAAAAAAGGCTAGAGGTTTCTTGGAATTTGTGGAGGATTTTATTCAGGTTCCTAGGAATCTCGT
TGGAAAAGTAATTGGAAAAAATGGCAAAGTTATTCAAGAAATAGTGGACAAATCTGGTGTGGTTCGAGTGAGAATTGAAGGGGACAATGAAAATAAATTA
CCCAGAGAAGACGGTATGGTTCCATTTGTATTTGTTGGCACTAAAGAAAGCATTGGAAATGTGCAGGTTCTTCTAGAGTATCATATTGCCTATCTAAAGG
AAGTAGAACAGCTAAGAATGGAACGCCTACAGATTGATGAACAGCTGCGACAGATTGGTTCTAGGTCTTATAGCGGAAGAGGCAGAGGTCGTCGGGGACC
TAATTACACCTCCGGTTATGGTACAAATTCTGAGCTGTCTAACCCCTCTGAAACGGAATCTGAGCGTAAAGACGAGCTGAGTGATTGGTCATTGGCAGGA
GAAGATGATCGAGACAGCCGACATCAGCGTGACAGCAGGAGACGCCCAGGAGGAAGAGGCAGAAGTGTTTCAGGGGGTCGAGGTCGTGGTGGACCACGTG
GTGGCAAATCCTCCATCAGTTCTGTGCTCAAAGATCCAGACAGCAATCCATACAGCTTACTTGATAATACAGAATCAGATCAGACTGCAGACACTGATGC
CAGCGAATCTCATCACAGTACTAACCGTCGTAGGCGGTCTCGTAGACGAAGGACTGATGAAGATGCTGTTCTGATGGATGGAATGACTGAATCTGATACA
GCTTCAGTTAATGAAAATGGGCTAGTCACAGTTGCAGATTATATTTCTAGAGCTGAGTCTCAGAGCAGACAAAGAAACCTCCCAAGGGAAACTTTGGCTA
AAAACAAGAAAGAAATGGCAAAAGATGTGATTGAAGAGCATGGTCCTTCAGAAAAGGCAATAAACGGCCCAACTAGTGCTTCTGGCGATGACATTTCTAA
GCTACAGCGTACTCCAGGAGAAGAAAAGATTAATACCTTAAAAGAAGAAAACACTCAAGAAGCAGCAGTCCTGAATGGTGTTTCATAAACTGAAGAAGTT
CCTAGTTTACAGTTCTTTTACATTACATTTACAATAGTGCTTGTACAAGCTTGCCAAAGATAGAATATGGATCGCCAGTCTTTACATCGCACTTTCAGTT
CCTCCATTTGGAATTCAAAAAGGGGAGGGATCCTGAAGAAATCATATGTTAAACATACTTTGACACCTACTGTGTTATAAAATATATCATCAGATGTGCC
TTGAGAATAGTATATGTAACATTAAAAAAAAGTTGCTGGCTATAGGAAATGTTATTTTGTTTTCAAAATATGGCAGAGATGGGGGGTGGTGGGTGGGGTG
GGATCCCTAACGTAATATTCTTTATGAAAGCATTAGCTGCTTTTGTTACATTTTTAATATGCAACCACTTCTTCACCTGAGGAAAACTAGAATGAAATGC
AGTCTAAAATATTTTGCACTGAATTGTAATTTCTTCATTAGTTTAGTCTGGAAACTGGTCTGTTTTAATGTGTTTTTTAAATGCTGTATGTAGAGGAAAA
TCTGCAGACCACTGGAATACATTTGTTAAACTCTCATCTGCAGGGACACTGGGCGATACTTGGCAGTGACTGTTCTACCTTGAGGCTTTGTTTGGTTTAT
TTATTAAAGTGTACAGTATTTAAAAATCAAACATAGCTTTAGTTAAAACACTAAGCTGAATTAGTCATGTCCATTCAGACATAACCTGAACTACTGAAAA
GATCAATTTCCAGAAGGTTTATTCTGTATAAACTACATGTTAGTCTTCAGTAGAGTATCTTTTTTTTTTCCTTTTTTTTTTTTTTATTTCGGTTGTTTGA
TGTGCAATATGTTTTTGTATGCAGGTAGTAAATAAACTTTGATCTTCCATTTGCTGAA
  • refseq_FXR1.F3 (forward primer)
  • refseq_FXR1.R3 (reverse primer)
  • Single exon skipping

Frame 0

QRPLRFQHGGADGGGSRL*RGFLQGIYQRCS*R
LPYSCF*K*LATRTPGSI**S*ITTTT*YKKRN*
*RR*SRGIFKSK*PRAMWVVVG*SSDDERRILC
H*ICCL*RYLQ*NSHI*TTSACQSK*NCQKKYL
L*MHSGCS*GFERGVC**KCT*RF*ESSRSMQNF
LPSRNNTANDTVCQ*SNCEESKHLK*HAFAKYS
YEVDAYVQK*RGH*AFRMHKTTCSSFS*GICCE
RRFNGPGNRNTW**HPAS*EGSWSYRH*AR*RYW
NIQNLRREC*CCKKG*RFLGICGGFYSGS*ESR
WKSNWKKWQSYSRNSGQIWCGSSEN*RGQ*K*I
TQRRRYGSICICWH*RKHWKCAGSSRVSYCLSKG
SRTAKNGTPTD**TAATDWF*VL*RKRQRSSGT
*LHLRLWYKF*AV*PL*NGI*A*RRAE*LVIGR
RR*SRQPTSA*QQETPRRKRQKCFRGSRSWWTTW
WQILHQFCAQRSRQQSIQLT**YRIRSDCRH*C
QRISSQY*PS*AVS*TKD**RCCSDGWND*I*Y
SFS**KWASHSCRLYF*S*VSEQTKKPPKGNFG*
KQERNGKRCD*RAWSFRKGNKRPN*CFWR*HF*
ATAYSRRRKD*YLKRRKHSRSSSPEWCFIN*RS
S*FTVLLHYIYNSACTSLPKIEYGSPVFTSHFQF
LHLEFKKGRDPEEIIC*TYFDTYCVIKYIIRCA
LRIVYVTLKKSCWL*EMLFCFQNMAEMGGGGWG
GIPNVIFFMKALAAFVTFLICNHFFT*GKLE*NA
V*NILH*IVISSLV*SGNWSVLMCFLNAVCRGK
SADHWNTFVKLSSAGTLGDTWQ*LFYLEALFGL
FIKVYSI*KSNIALVKTLS*ISHVHSDIT*TTEK
INFQKVYSV*TTC*SSVEYLFFFLFFFFISVV*
CAICFCMQVVNKL*SSIC*

Frame 1

SGLCGSNMAELTVEVRGSNGAFYKGFIKDVHED
SLTVVFENNWQPERQVPFNEVRLPPPPDIKKEI
SEGDEVEVYSRANDQEPCGWWLAKVRMMKGEFYV
IEYAACDATYNEIVTFERLRPVNQNKTVKKNTF
FKCTVDVPEDLREACANENAHKDFKKAVGACRI
FYHPETTQLMILSASEATVKRVNILSDMHLRSIR
TKLMLMSRNEEATKHLECTKQLAAAFHEEFVVR
EDLMGLAIGTHGSNIQQARKVPGVTAIELDEDT
GTFRIYGESADAVKKARGFLEFVEDFIQVPRNLV
GKVIGKNGKVIQEIVDKSGVVRVRIEGDNENKL
PREDGMVPFVFVGTKESIGNVQVLLEYHIAYLK
EVEQLRMERLQIDEQLRQIGSRSYSGRGRGRRGP
NYTSGYGTNSELSNPSETESERKDELSDWSLAG
EDDRDSRHQRDSRRRPGGRGRSVSGGRGRGGPR
GGKSSISSVLKDPDSNPYSLLDNTESDQTADTDA
SESHHSTNRRRRSRRRRTDEDAVLMDGMTESDT
ASVNENGLVTVADYISRAESQSRQRNLPRETLA
KNKKEMAKDVIEEHGPSEKAINGPTSASGDDISK
LQRTPGEEKINTLKEENTQEAAVLNGVS*TEEV
PSLQFFYITFTIVLVQACQR*NMDRQSLHRTFS
SSIWNSKRGGILKKSYVKHTLTPTVL*NISSDVP
*E*YM*H*KKVAGYRKCYFVFKIWQRWGVVGGV
GSLT*YSL*KH*LLLLHF*YATTSSPEEN*NEM
QSKIFCTEL*FLH*FSLETGLF*CVF*MLYVEEN
LQTTGIHLLNSHLQGHWAILGSDCSTLRLCLVY
LLKCTVFKNQT*L*LKH*AELVMSIQT*PELLK
RSISRRFILYKLHVSLQ*SIFFFSFFFFLFRLFD
VQYVFVCR**INFDLPFAE

Frame 2

AAFAVPTWRS*RWRFAALTGLSTRDLSKMFMKT
PLQLFLKIIGNQNARFHLMKLDYHHHLI*KKKL
VKEMK*RYIQEQMTKSHVGGGWLKFG**KENFM
SLNMLLVTLLTMK*SHLNDFGLSIKIKLSKKIPS
LNAQWMFLRI*ERRVLMKMHIKILRKQ*EHAEF
FTIQKQHS**YCLPVKQL*RE*TS*VTCICEVF
VRS*CLCPEMKRPLSI*NAQNNLQQLFMRNLL*E
KI*WAWQ*EHMVVTSSKLGRFLELPPLS*MKIL
EHSESTERVLML*KRLEVSWNLWRILFRFLGIS
LEK*LEKMAKLFKK*WTNLVWFE*ELKGTMKINY
PEKTVWFHLYLLALKKALEMCRFF*SIILPI*R
K*NS*EWNAYRLMNSCDRLVLGLIAEEAEVVGD
LITPPVMVQILSCLTPLKRNLSVKTS*VIGHWQE
KMIETADISVTAGDAQEEEAEVFQGVEVVVDHV
VANPPSVLCSKIQTAIHTAYLIIQNQIRLQTLM
PANLITVLTVVGGLVDEGLMKMLF*WME*LNLIQ
LQLMKMG*SQLQIIFLELSLRADKETSQGKLWL
KTRKKWQKM*LKSMVLQKRQ*TAQLVLLAMTFL
SYSVLQEKKRLIP*KKKTLKKQQS*MVFHKLKKF
LVYSSFTLHLQ*CLYKLAKDRIWIASLYIALSV
PPFGIQKGEGS*RNHMLNIL*HLLCYKIYHQMC
LENSICNIKKKLLAIGNVILFSKYGRDGGWWVGW
DP*RNILYESISCFCYIFNMQPLLHLRKTRMKC
SLKYFALNCNFFISLVWKLVCFNVFFKCCM*RK
ICRPLEYIC*TLICRDTGRYLAVTVLP*GFVWFI
Y*SVQYLKIKHSFS*NTKLN*SCPFRHNLNY*K
DQFPEGLFCINYMLVFSRVSFFFPFFFFYFGCL
MCNMFLYAGSK*TLIFHLL

Copyright ©2008,2017, all rights reserved.