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Sequences

Sequence NM_181310

CTCACTTTACCACTACTCGCTATAGAGCCCTGGTCAAGTTCTCTCCACCTCTCTATCTATGTCTCAGTTTCTTCATCTGTAACATCAAATGAATAATAAT ACCAATCTCCTAGACTTCATAAGAGGATTAACAAAGACAAAATATGGGAAAAACATAACATGGCGTCCCATAATTATTAGATCTTATTATTGACACTAAA ATGGCATTAAAATTACCAAAAGGAAGACAGCATCTGTTTCCTCTTTGGTCCTGAGCTGGTTAAAAGGAACACTGGTTGCCTGAACAGTCACACTTGCAAC CATGATGCCTAAACATTGCTTTCTAGGCTTCCTCATCAGTTTCTTCCTTACTGGTGTAGCAGGAACTCAGTCAACGCATGAGTCTCTGAAGCCTCAGAGG GTACAATTTCAGTCCCGAAATTTTCACAACATTTTGCAATGGCAGCCTGGGAGGGCACTTACTGGCAACAGCAGTGTCTATTTTGTGCAGTACAAAATAT ATGGACAGAGACAATGGAAAAATAAAGAAGACTGTTGGGGTACTCAAGAACTCTCTTGTGACCTTACCAGTGAAACCTCAGACATACAGGAACCTTATTA CGGGAGGGTGAGGGCGGCCTCGGCTGGGAGCTACTCAGAATGGAGCATGACGCCGCGGTTCACTCCCTGGTGGGAAAGAGCAAAAGGTTTATGAAGGGGC TCACAGAGCGGTTGAAATTGAAGCTCTAACACCACACTCCAGCTACTGTGTAGTGGCTGAAATATATCAGCCCATGTTAGACAGAAGAAGTCAGAGAAGT GAAGAGAGATGTGTGGAAATTCCATGACTTGTGGAATTTGGCATTCAGCAATGTGGAAATTCTAAAGCTCCCTGAGAACAGGATGACTCGTGTTTGAAGG ATCTTATTTAAAATTGTTTTTGTATTTTCTTAAAGCAATATTCACTGTTACACCTTGGGGACTTCTTTGTTTATCCATTCTTTTATCCTTTATATTTCAT TTGTAAACTATATTTGAACGACATTCCCCCCGAAAAATTGAAATGTAAAGATGAGGCAGAGAATAAAGTGTTCTATGAAATTCAGAACTTTATTTCTGAA TGTAACATCCCTAATAACAACCTTCATTCTTCTAATACAGCAAAATAAAAATTTAACAACCAAGGAATAGTATTTAAGAAAATGTTGAAATAATTTTTTT AAAATAGCATTACAGACTGAGGCGGTCCTGAAGCAATGGTTTTTCACTCTCTTATTGAGCCAATTAAATTGACATTGCTTTGACAATTTAAAACTTCTAT AAAGGTGAATATTTTTCATACATTTCTATTTTATATGAATATACTTTTTATATATTTATTATTATTAAATATTTCTACTTAATGAATCAAAATTTTGTTT TAAAGTCTACTTTATGTAAATAAGAACAGGTTTTGGGGAAAAAAATCTTATGATTTCTGGATTGATATCTGAATTAAAACTATCAACAACAAGGAAGTCT GCTCTGTACAATTGTCCCTCATTTAAAAGATATATTAAGCTTTTCTTTTCTGTTTGTTTTTGTTTTGTTTAGTTTTTAATCCTGTCTTAGAAGAACTTAT CTTTATTCTCAAAATTAAATGTAATTTTTTTAGTGACAAAGAAGAAAGGAAACCTCATTACTCAATCCTTCTGGCCAAGAGTGTCTTGCTTGTGGCGCCT TCCTCATCTCTATATAGGAGGATCCCATGAATGATGGTTTATTGGGAACTGCTGGGGTCGACCCCATACAGAGAACTCAGCTTGAAGCTGGAAGCACACA GTGGGTAGCAGGAGAAGGACCGGTGTTGGTAGGTGCCTACAGAGACTATAGAGCTAGACAAAGCCCTCCAAACTGGCCCCTCCTGCTCACTGCCTCTCCT GAGTAGAAATCTGGTGACCTAAGGCTCAGTGTGGTCAACAGAAAGCTGCCTTCTTCACTTGAGGCTAAGTCTTCATATATGTTTAAGGTTGTCTTTCTAG TGAGGAGATACATATCAGAGAACATTTGTACAATTCCCCATGAAAATTGCTCCAAAGTTGATAACAATATAGTCGGTGCTTCTAGTTATATGCAAGTACT CAGTGATAAATGGATTAAAAAATATTCAGAAATGTATTGGGGGGTGGAGGAGAATAAGAGGCAGAGCAAGAGCTAGAGAATTGGTTTCCTTGCTTCCCTG TATGCTCAGAAAACATTGATTTGAGCATAGACGCAGAGACTGAAAAAAAAATTTACTTTGATCTCTGTTTTTGAATTCTTATTATTTATATTTTGCTTAC TACCTTTTTTGCCTTTTGTCCTTTTGTGGAGAGGGCGATGAATTAAGAGTAGTGGGGTGGGTGGCGAGTAAGTAAAATTTCAAATAGCATTTTAGTGAAT GCAATTCAGTAGTCCTGAAGCCTGACTTAATAAAACAAAATTCATTTATGGTTGTTTCATGAAAGTTATTAGATAGGATCAAGTTTTGTTTGTATATTGT TTGCCTTGCTCTGTTTTTGCTTTTGTGCTTAGGCAAGTGCAAAATACTCTATGGAAATCATAATTGTCATCTTCTTCATGGTGTTAGGGATATATTGTCA CATGATTTCAATAAATCCTTTTTTTGCTTTA

refseq_IL22RA2.F2 (forward primer)
refseq_IL22RA2.R2 (reverse primer)
Single exon skipping

Frame 0

LTLPLLAIEPWSSSLHLSIYVSVSSSVTSNE** YQSPRLHKRINKDKIWEKHNMASHNY*ILLLTLK WH*NYQKEDSICFLFGPELVKRNTGCLNSHTCN HDA*TLLSRLPHQFLPYWCSRNSVNA*VSEASE GTISVPKFSQHFAMAAWEGTYWQQQCLFCAVQNI WTETMEK*RRLLGYSRTLL*PYQ*NLRHTGTLL REGEGGLGWELLRMEHDAAVHSLVGKSKRFMKG LTERLKLKL*HHTPATV*WLKYISPC*TEEVREV KRDVWKFHDLWNLAFSNVEILKLPENRMTRV*R ILFKIVFVFS*SNIHCYTLGTSLFIHSFILYIS FVNYI*TTFPPKN*NVKMRQRIKCSMKFRTLFLN VTSLITTFILLIQQNKNLTTKE*YLRKC*NNFF KIALQTEAVLKQWFFTLLLSQLN*HCFDNLKLL *R*IFFIHFYFI*IYFLYIYYY*IFLLNESKFCF KVYFM*IRTGFGEKNLMISGLISELKLSTTRKS ALYNCPSFKRYIKLFFSVCFCFV*FLILS*KNL SLFSKLNVIFLVTKKKGNLITQSFWPRVSCLWRL PHLYIGGSHE*WFIGNCWGRPHTENSA*SWKHT VGSRRRTGVGRCLQRL*S*TKPSKLAPPAHCLS *VEIW*PKAQCGQQKAAFFT*G*VFIYV*GCLSS EEIHIREHLYNSP*KLLQS**QYSRCF*LYAST Q**MD*KIFRNVLGGGGE*EAEQELENWFPCFP VCSENIDLSIDAETEKKIYFDLCF*ILIIYILLT TFFAFCPFVERAMN*E*WGGWRVSKISNSILVN AIQ*S*SLT**NKIHLWLFHESY*IGSSFVCIL FALLCFCFCA*ASAKYSMEIIIVIFFMVLGIYCH MISINPFFAL

Frame 1

SLYHYSL*SPGQVLSTSLSMSQFLHL*HQMNNN TNLLDFIRGLTKTKYGKNITWRPIIIRSYY*H* NGIKITKRKTASVSSLVLSWLKGTLVA*TVTLAT MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQR VQFQSRNFHNILQWQPGRALTGNSSVYFVQYKI YGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYY GRVRAASAGSYSEWSMTPRFTPWWERAKGL*RG SQSG*N*SSNTTLQLLCSG*NISAHVRQKKSEK *REMCGNSMTCGIWHSAMWKF*SSLRTG*LVFEG SYLKLFLYFLKAIFTVTPWGLLCLSILLSFIFH L*TIFERHSPRKIEM*R*GRE*SVL*NSELYF* M*HP**QPSFF*YSKIKI*QPRNSI*ENVEIIFL K*HYRLRRS*SNGFSLSY*AN*IDIALTI*NFY KGEYFSYISILYEYTFYIFIIIKYFYLMNQNFV LKSTLCK*EQVLGKKIL*FLD*YLN*NYQQQGSL LCTIVPHLKDILSFSFLFVFVLFSF*SCLRRTY LYSQN*M*FF**QRRKETSLLNPSGQECLACGA FLISI*EDPMNDGLLGTAGVDPIQRTQLEAGSTQ WVAGEGPVLVGAYRDYRARQSPPNWPLLLTASP E*KSGDLRLSVVNRKLPSSLEAKSSYMFKVVFL VRRYISENICTIPHENCSKVDNNIVGASSYMQVL SDKWIKKYSEMYWGVEENKRQSKS*RIGFLASL YAQKTLI*A*TQRLKKKFTLISVFEFLLFIFCL LPFLPFVLLWRGR*IKSSGVGGE*VKFQIAF**M QFSSPEA*LNKTKFIYGCFMKVIR*DQVLFVYC LPCSVFAFVLRQVQNTLWKS*LSSSSWC*GYIV T*FQ*ILFLL

Frame 2

HFTTTRYRALVKFSPPLYLCLSFFICNIK*III PIS*TS*ED*QRQNMGKT*HGVP*LLDLIIDTK MALKLPKGRQHLFPLWS*AG*KEHWLPEQSHLQ P*CLNIAF*ASSSVSSLLV*QELSQRMSL*SLRG YNFSPEIFTTFCNGSLGGHLLATAVSILCSTKY MDRDNGKIKKTVGVLKNSLVTLPVKPQTYRNLI TGG*GRPRLGATQNGA*RRGSLPGGKEQKVYEGA HRAVEIEALTPHSSYCVVAEIYQPMLDRRSQRS EERCVEIP*LVEFGIQQCGNSKAP*EQDDSCLK DLI*NCFCIFLKQYSLLHLGDFFVYPFFYPLYFI CKLYLNDIPPEKLKCKDEAENKVFYEIQNFISE CNIPNNNLHSSNTAK*KFNNQGIVFKKMLK*FF *NSITD*GGPEAMVFHSLIEPIKLTLL*QFKTSI KVNIFHTFLFYMNILFIYLLLLNIST**IKILF *SLLYVNKNRFWGKKSYDFWIDI*IKTINNKEV CSVQLSLI*KIY*AFLFCLFLFCLVFNPVLEELI FILKIKCNFFSDKEERKPHYSILLAKSVLLVAP SSSLYRRIP*MMVYWELLGSTPYRELSLKLEAH SG*QEKDRCW*VPTETIELDKALQTGPSCSLPLL SRNLVT*GSVWSTESCLLHLRLSLHICLRLSF* *GDTYQRTFVQFPMKIAPKLITI*SVLLVICKY SVINGLKNIQKCIGGWRRIRGRARARELVSLLPC MLRKH*FEHRRRD*KKNLL*SLFLNSYYLYFAY YLFCLLSFCGEGDELRVVGWVASK*NFK*HFSE CNSVVLKPDLIKQNSFMVVS*KLLDRIKFCLYIV CLALFLLLCLGKCKILYGNHNCHLLHGVRDILS HDFNKSFFCF

Sequence NM_181309

CTCACTTTACCACTACTCGCTATAGAGCCCTGGTCAAGTTCTCTCCACCTCTCTATCTATGTCTCAGTTTCTTCATCTGTAACATCAAATGAATAATAAT ACCAATCTCCTAGACTTCATAAGAGGATTAACAAAGACAAAATATGGGAAAAACATAACATGGCGTCCCATAATTATTAGATCTTATTATTGACACTAAA ATGGCATTAAAATTACCAAAAGGAAGACAGCATCTGTTTCCTCTTTGGTCCTGAGCTGGTTAAAAGGAACACTGGTTGCCTGAACAGTCACACTTGCAAC CATGATGCCTAAACATTGCTTTCTAGGCTTCCTCATCAGTTTCTTCCTTACTGGTGTAGCAGGAACTCAGTCAACGCATGAGTCTCTGAAGCCTCAGAGG GTACAATTTCAGTCCCGAAATTTTCACAACATTTTGCAATGGCAGCCTGGGAGGGCACTTACTGGCAACAGCAGTGTCTATTTTGTGCAGTACAAAATAT ATGGACAGAGACAATGGAAAAATAAAGAAGACTGTTGGGGTACTCAAGAACTCTCTTGTGACCTTACCAGTGAAACCTCAGACATACAGGAACCTTATTA CGGGAGGGTGAGGGCGGCCTCGGCTGGGAGCTACTCAGAATGGAGCATGACGCCGCGGTTCACTCCCTGGTGGGAAACAAAAATAGATCCTCCAGTCATG AATATAACCCAAGTCAATGGCTCTTTGTTGGTAATTCTCCATGCTCCAAATTTACCATATAGATACCAAAAGGAAAAAAATGTATCTATAGAAGATTACT ATGAACTACTATACCGAGTTTTTATAATTAACAATTCACTAGAAAAGGAGCAAAAGGTTTATGAAGGGGCTCACAGAGCGGTTGAAATTGAAGCTCTAAC ACCACACTCCAGCTACTGTGTAGTGGCTGAAATATATCAGCCCATGTTAGACAGAAGAAGTCAGAGAAGTGAAGAGAGATGTGTGGAAATTCCATGACTT GTGGAATTTGGCATTCAGCAATGTGGAAATTCTAAAGCTCCCTGAGAACAGGATGACTCGTGTTTGAAGGATCTTATTTAAAATTGTTTTTGTATTTTCT TAAAGCAATATTCACTGTTACACCTTGGGGACTTCTTTGTTTATCCATTCTTTTATCCTTTATATTTCATTTGTAAACTATATTTGAACGACATTCCCCC CGAAAAATTGAAATGTAAAGATGAGGCAGAGAATAAAGTGTTCTATGAAATTCAGAACTTTATTTCTGAATGTAACATCCCTAATAACAACCTTCATTCT TCTAATACAGCAAAATAAAAATTTAACAACCAAGGAATAGTATTTAAGAAAATGTTGAAATAATTTTTTTAAAATAGCATTACAGACTGAGGCGGTCCTG AAGCAATGGTTTTTCACTCTCTTATTGAGCCAATTAAATTGACATTGCTTTGACAATTTAAAACTTCTATAAAGGTGAATATTTTTCATACATTTCTATT TTATATGAATATACTTTTTATATATTTATTATTATTAAATATTTCTACTTAATGAATCAAAATTTTGTTTTAAAGTCTACTTTATGTAAATAAGAACAGG TTTTGGGGAAAAAAATCTTATGATTTCTGGATTGATATCTGAATTAAAACTATCAACAACAAGGAAGTCTGCTCTGTACAATTGTCCCTCATTTAAAAGA TATATTAAGCTTTTCTTTTCTGTTTGTTTTTGTTTTGTTTAGTTTTTAATCCTGTCTTAGAAGAACTTATCTTTATTCTCAAAATTAAATGTAATTTTTT TAGTGACAAAGAAGAAAGGAAACCTCATTACTCAATCCTTCTGGCCAAGAGTGTCTTGCTTGTGGCGCCTTCCTCATCTCTATATAGGAGGATCCCATGA ATGATGGTTTATTGGGAACTGCTGGGGTCGACCCCATACAGAGAACTCAGCTTGAAGCTGGAAGCACACAGTGGGTAGCAGGAGAAGGACCGGTGTTGGT AGGTGCCTACAGAGACTATAGAGCTAGACAAAGCCCTCCAAACTGGCCCCTCCTGCTCACTGCCTCTCCTGAGTAGAAATCTGGTGACCTAAGGCTCAGT GTGGTCAACAGAAAGCTGCCTTCTTCACTTGAGGCTAAGTCTTCATATATGTTTAAGGTTGTCTTTCTAGTGAGGAGATACATATCAGAGAACATTTGTA CAATTCCCCATGAAAATTGCTCCAAAGTTGATAACAATATAGTCGGTGCTTCTAGTTATATGCAAGTACTCAGTGATAAATGGATTAAAAAATATTCAGA AATGTATTGGGGGGTGGAGGAGAATAAGAGGCAGAGCAAGAGCTAGAGAATTGGTTTCCTTGCTTCCCTGTATGCTCAGAAAACATTGATTTGAGCATAG ACGCAGAGACTGAAAAAAAAATTTACTTTGATCTCTGTTTTTGAATTCTTATTATTTATATTTTGCTTACTACCTTTTTTGCCTTTTGTCCTTTTGTGGA GAGGGCGATGAATTAAGAGTAGTGGGGTGGGTGGCGAGTAAGTAAAATTTCAAATAGCATTTTAGTGAATGCAATTCAGTAGTCCTGAAGCCTGACTTAA TAAAACAAAATTCATTTATGGTTGTTTCATGAAAGTTATTAGATAGGATCAAGTTTTGTTTGTATATTGTTTGCCTTGCTCTGTTTTTGCTTTTGTGCTT AGGCAAGTGCAAAATACTCTATGGAAATCATAATTGTCATCTTCTTCATGGTGTTAGGGATATATTGTCACATGATTTCAATAAATCCTTTTTTTGCTTT A

refseq_IL22RA2.F2 (forward primer)
refseq_IL22RA2.R2 (reverse primer)
Single exon skipping

Frame 0

LTLPLLAIEPWSSSLHLSIYVSVSSSVTSNE** YQSPRLHKRINKDKIWEKHNMASHNY*ILLLTLK WH*NYQKEDSICFLFGPELVKRNTGCLNSHTCN HDA*TLLSRLPHQFLPYWCSRNSVNA*VSEASE GTISVPKFSQHFAMAAWEGTYWQQQCLFCAVQNI WTETMEK*RRLLGYSRTLL*PYQ*NLRHTGTLL REGEGGLGWELLRMEHDAAVHSLVGNKNRSSSH EYNPSQWLFVGNSPCSKFTI*IPKGKKCIYRRLL *TTIPSFYN*QFTRKGAKGL*RGSQSG*N*SSN TTLQLLCSG*NISAHVRQKKSEK*REMCGNSMT CGIWHSAMWKF*SSLRTG*LVFEGSYLKLFLYFL KAIFTVTPWGLLCLSILLSFIFHL*TIFERHSP RKIEM*R*GRE*SVL*NSELYF*M*HP**QPSF F*YSKIKI*QPRNSI*ENVEIIFLK*HYRLRRS* SNGFSLSY*AN*IDIALTI*NFYKGEYFSYISI LYEYTFYIFIIIKYFYLMNQNFVLKSTLCK*EQ VLGKKIL*FLD*YLN*NYQQQGSLLCTIVPHLKD ILSFSFLFVFVLFSF*SCLRRTYLYSQN*M*FF **QRRKETSLLNPSGQECLACGAFLISI*EDPM NDGLLGTAGVDPIQRTQLEAGSTQWVAGEGPVLV GAYRDYRARQSPPNWPLLLTASPE*KSGDLRLS VVNRKLPSSLEAKSSYMFKVVFLVRRYISENIC TIPHENCSKVDNNIVGASSYMQVLSDKWIKKYSE MYWGVEENKRQSKS*RIGFLASLYAQKTLI*A* TQRLKKKFTLISVFEFLLFIFCLLPFLPFVLLW RGR*IKSSGVGGE*VKFQIAF**MQFSSPEA*LN KTKFIYGCFMKVIR*DQVLFVYCLPCSVFAFVL RQVQNTLWKS*LSSSSWC*GYIVT*FQ*ILFLL

Frame 1

SLYHYSL*SPGQVLSTSLSMSQFLHL*HQMNNN TNLLDFIRGLTKTKYGKNITWRPIIIRSYY*H* NGIKITKRKTASVSSLVLSWLKGTLVA*TVTLAT MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQR VQFQSRNFHNILQWQPGRALTGNSSVYFVQYKI YGQRQWKNKEDCWGTQELSCDLTSETSDIQEPYY GRVRAASAGSYSEWSMTPRFTPWWETKIDPPVM NITQVNGSLLVILHAPNLPYRYQKEKNVSIEDY YELLYRVFIINNSLEKEQKVYEGAHRAVEIEALT PHSSYCVVAEIYQPMLDRRSQRSEERCVEIP*L VEFGIQQCGNSKAP*EQDDSCLKDLI*NCFCIF LKQYSLLHLGDFFVYPFFYPLYFICKLYLNDIPP EKLKCKDEAENKVFYEIQNFISECNIPNNNLHS SNTAK*KFNNQGIVFKKMLK*FF*NSITD*GGP EAMVFHSLIEPIKLTLL*QFKTSIKVNIFHTFLF YMNILFIYLLLLNIST**IKILF*SLLYVNKNR FWGKKSYDFWIDI*IKTINNKEVCSVQLSLI*K IY*AFLFCLFLFCLVFNPVLEELIFILKIKCNFF SDKEERKPHYSILLAKSVLLVAPSSSLYRRIP* MMVYWELLGSTPYRELSLKLEAHSG*QEKDRCW *VPTETIELDKALQTGPSCSLPLLSRNLVT*GSV WSTESCLLHLRLSLHICLRLSF**GDTYQRTFV QFPMKIAPKLITI*SVLLVICKYSVINGLKNIQ KCIGGWRRIRGRARARELVSLLPCMLRKH*FEHR RRD*KKNLL*SLFLNSYYLYFAYYLFCLLSFCG EGDELRVVGWVASK*NFK*HFSECNSVVLKPDL IKQNSFMVVS*KLLDRIKFCLYIVCLALFLLLCL GKCKILYGNHNCHLLHGVRDILSHDFNKSFFCF

Frame 2

HFTTTRYRALVKFSPPLYLCLSFFICNIK*III PIS*TS*ED*QRQNMGKT*HGVP*LLDLIIDTK MALKLPKGRQHLFPLWS*AG*KEHWLPEQSHLQ P*CLNIAF*ASSSVSSLLV*QELSQRMSL*SLRG YNFSPEIFTTFCNGSLGGHLLATAVSILCSTKY MDRDNGKIKKTVGVLKNSLVTLPVKPQTYRNLI TGG*GRPRLGATQNGA*RRGSLPGGKQK*ILQS* I*PKSMALCW*FSMLQIYHIDTKRKKMYL*KIT MNYYTEFL*LTIH*KRSKRFMKGLTERLKLKL* HHTPATV*WLKYISPC*TEEVREVKRDVWKFHDL WNLAFSNVEILKLPENRMTRV*RILFKIVFVFS *SNIHCYTLGTSLFIHSFILYISFVNYI*TTFP PKN*NVKMRQRIKCSMKFRTLFLNVTSLITTFIL LIQQNKNLTTKE*YLRKC*NNFFKIALQTEAVL KQWFFTLLLSQLN*HCFDNLKLL*R*IFFIHFY FI*IYFLYIYYY*IFLLNESKFCFKVYFM*IRTG FGEKNLMISGLISELKLSTTRKSALYNCPSFKR YIKLFFSVCFCFV*FLILS*KNLSLFSKLNVIF LVTKKKGNLITQSFWPRVSCLWRLPHLYIGGSHE *WFIGNCWGRPHTENSA*SWKHTVGSRRRTGVG RCLQRL*S*TKPSKLAPPAHCLS*VEIW*PKAQ CGQQKAAFFT*G*VFIYV*GCLSSEEIHIREHLY NSP*KLLQS**QYSRCF*LYASTQ**MD*KIFR NVLGGGGE*EAEQELENWFPCFPVCSENIDLSI DAETEKKIYFDLCF*ILIIYILLTTFFAFCPFVE RAMN*E*WGGWRVSKISNSILVNAIQ*S*SLT* *NKIHLWLFHESY*IGSSFVCILFALLCFCFCA *ASAKYSMEIIIVIFFMVLGIYCHMISINPFFAL

Sequence NM_052962

CTCACTTTACCACTACTCGCTATAGAGCCCTGGTCAAGTTCTCTCCACCTCTCTATCTATGTCTCAGTTTCTTCATCTGTAACATCAAATGAATAATAAT ACCAATCTCCTAGACTTCATAAGAGGATTAACAAAGACAAAATATGGGAAAAACATAACATGGCGTCCCATAATTATTAGATCTTATTATTGACACTAAA ATGGCATTAAAATTACCAAAAGGAAGACAGCATCTGTTTCCTCTTTGGTCCTGAGCTGGTTAAAAGGAACACTGGTTGCCTGAACAGTCACACTTGCAAC CATGATGCCTAAACATTGCTTTCTAGGCTTCCTCATCAGTTTCTTCCTTACTGGTGTAGCAGGAACTCAGTCAACGCATGAGTCTCTGAAGCCTCAGAGG GTACAATTTCAGTCCCGAAATTTTCACAACATTTTGCAATGGCAGCCTGGGAGGGCACTTACTGGCAACAGCAGTGTCTATTTTGTGCAGTACAAAATCA TGTTCTCATGCAGCATGAAAAGCTCTCACCAGAAGCCAAGTGGATGCTGGCAGCACATTTCTTGTAACTTCCCAGGCTGCAGAACATTGGCTAAATATGG ACAGAGACAATGGAAAAATAAAGAAGACTGTTGGGGTACTCAAGAACTCTCTTGTGACCTTACCAGTGAAACCTCAGACATACAGGAACCTTATTACGGG AGGGTGAGGGCGGCCTCGGCTGGGAGCTACTCAGAATGGAGCATGACGCCGCGGTTCACTCCCTGGTGGGAAACAAAAATAGATCCTCCAGTCATGAATA TAACCCAAGTCAATGGCTCTTTGTTGGTAATTCTCCATGCTCCAAATTTACCATATAGATACCAAAAGGAAAAAAATGTATCTATAGAAGATTACTATGA ACTACTATACCGAGTTTTTATAATTAACAATTCACTAGAAAAGGAGCAAAAGGTTTATGAAGGGGCTCACAGAGCGGTTGAAATTGAAGCTCTAACACCA CACTCCAGCTACTGTGTAGTGGCTGAAATATATCAGCCCATGTTAGACAGAAGAAGTCAGAGAAGTGAAGAGAGATGTGTGGAAATTCCATGACTTGTGG AATTTGGCATTCAGCAATGTGGAAATTCTAAAGCTCCCTGAGAACAGGATGACTCGTGTTTGAAGGATCTTATTTAAAATTGTTTTTGTATTTTCTTAAA GCAATATTCACTGTTACACCTTGGGGACTTCTTTGTTTATCCATTCTTTTATCCTTTATATTTCATTTGTAAACTATATTTGAACGACATTCCCCCCGAA AAATTGAAATGTAAAGATGAGGCAGAGAATAAAGTGTTCTATGAAATTCAGAACTTTATTTCTGAATGTAACATCCCTAATAACAACCTTCATTCTTCTA ATACAGCAAAATAAAAATTTAACAACCAAGGAATAGTATTTAAGAAAATGTTGAAATAATTTTTTTAAAATAGCATTACAGACTGAGGCGGTCCTGAAGC AATGGTTTTTCACTCTCTTATTGAGCCAATTAAATTGACATTGCTTTGACAATTTAAAACTTCTATAAAGGTGAATATTTTTCATACATTTCTATTTTAT ATGAATATACTTTTTATATATTTATTATTATTAAATATTTCTACTTAATGAATCAAAATTTTGTTTTAAAGTCTACTTTATGTAAATAAGAACAGGTTTT GGGGAAAAAAATCTTATGATTTCTGGATTGATATCTGAATTAAAACTATCAACAACAAGGAAGTCTGCTCTGTACAATTGTCCCTCATTTAAAAGATATA TTAAGCTTTTCTTTTCTGTTTGTTTTTGTTTTGTTTAGTTTTTAATCCTGTCTTAGAAGAACTTATCTTTATTCTCAAAATTAAATGTAATTTTTTTAGT GACAAAGAAGAAAGGAAACCTCATTACTCAATCCTTCTGGCCAAGAGTGTCTTGCTTGTGGCGCCTTCCTCATCTCTATATAGGAGGATCCCATGAATGA TGGTTTATTGGGAACTGCTGGGGTCGACCCCATACAGAGAACTCAGCTTGAAGCTGGAAGCACACAGTGGGTAGCAGGAGAAGGACCGGTGTTGGTAGGT GCCTACAGAGACTATAGAGCTAGACAAAGCCCTCCAAACTGGCCCCTCCTGCTCACTGCCTCTCCTGAGTAGAAATCTGGTGACCTAAGGCTCAGTGTGG TCAACAGAAAGCTGCCTTCTTCACTTGAGGCTAAGTCTTCATATATGTTTAAGGTTGTCTTTCTAGTGAGGAGATACATATCAGAGAACATTTGTACAAT TCCCCATGAAAATTGCTCCAAAGTTGATAACAATATAGTCGGTGCTTCTAGTTATATGCAAGTACTCAGTGATAAATGGATTAAAAAATATTCAGAAATG TATTGGGGGGTGGAGGAGAATAAGAGGCAGAGCAAGAGCTAGAGAATTGGTTTCCTTGCTTCCCTGTATGCTCAGAAAACATTGATTTGAGCATAGACGC AGAGACTGAAAAAAAAATTTACTTTGATCTCTGTTTTTGAATTCTTATTATTTATATTTTGCTTACTACCTTTTTTGCCTTTTGTCCTTTTGTGGAGAGG GCGATGAATTAAGAGTAGTGGGGTGGGTGGCGAGTAAGTAAAATTTCAAATAGCATTTTAGTGAATGCAATTCAGTAGTCCTGAAGCCTGACTTAATAAA ACAAAATTCATTTATGGTTGTTTCATGAAAGTTATTAGATAGGATCAAGTTTTGTTTGTATATTGTTTGCCTTGCTCTGTTTTTGCTTTTGTGCTTAGGC AAGTGCAAAATACTCTATGGAAATCATAATTGTCATCTTCTTCATGGTGTTAGGGATATATTGTCACATGATTTCAATAAATCCTTTTTTTGCTTTA

refseq_IL22RA2.F2 (forward primer)
refseq_IL22RA2.R2 (reverse primer)
Single exon skipping

Frame 0

LTLPLLAIEPWSSSLHLSIYVSVSSSVTSNE** YQSPRLHKRINKDKIWEKHNMASHNY*ILLLTLK WH*NYQKEDSICFLFGPELVKRNTGCLNSHTCN HDA*TLLSRLPHQFLPYWCSRNSVNA*VSEASE GTISVPKFSQHFAMAAWEGTYWQQQCLFCAVQNH VLMQHEKLSPEAKWMLAAHFL*LPRLQNIG*IW TETMEK*RRLLGYSRTLL*PYQ*NLRHTGTLLR EGEGGLGWELLRMEHDAAVHSLVGNKNRSSSHEY NPSQWLFVGNSPCSKFTI*IPKGKKCIYRRLL* TTIPSFYN*QFTRKGAKGL*RGSQSG*N*SSNT TLQLLCSG*NISAHVRQKKSEK*REMCGNSMTCG IWHSAMWKF*SSLRTG*LVFEGSYLKLFLYFLK AIFTVTPWGLLCLSILLSFIFHL*TIFERHSPR KIEM*R*GRE*SVL*NSELYF*M*HP**QPSFF* YSKIKI*QPRNSI*ENVEIIFLK*HYRLRRS*S NGFSLSY*AN*IDIALTI*NFYKGEYFSYISIL YEYTFYIFIIIKYFYLMNQNFVLKSTLCK*EQVL GKKIL*FLD*YLN*NYQQQGSLLCTIVPHLKDI LSFSFLFVFVLFSF*SCLRRTYLYSQN*M*FF* *QRRKETSLLNPSGQECLACGAFLISI*EDPMND GLLGTAGVDPIQRTQLEAGSTQWVAGEGPVLVG AYRDYRARQSPPNWPLLLTASPE*KSGDLRLSV VNRKLPSSLEAKSSYMFKVVFLVRRYISENICTI PHENCSKVDNNIVGASSYMQVLSDKWIKKYSEM YWGVEENKRQSKS*RIGFLASLYAQKTLI*A*T QRLKKKFTLISVFEFLLFIFCLLPFLPFVLLWRG R*IKSSGVGGE*VKFQIAF**MQFSSPEA*LNK TKFIYGCFMKVIR*DQVLFVYCLPCSVFAFVLR QVQNTLWKS*LSSSSWC*GYIVT*FQ*ILFLL

Frame 1

SLYHYSL*SPGQVLSTSLSMSQFLHL*HQMNNN TNLLDFIRGLTKTKYGKNITWRPIIIRSYY*H* NGIKITKRKTASVSSLVLSWLKGTLVA*TVTLAT MMPKHCFLGFLISFFLTGVAGTQSTHESLKPQR VQFQSRNFHNILQWQPGRALTGNSSVYFVQYKI MFSCSMKSSHQKPSGCWQHISCNFPGCRTLAKYG QRQWKNKEDCWGTQELSCDLTSETSDIQEPYYG RVRAASAGSYSEWSMTPRFTPWWETKIDPPVMN ITQVNGSLLVILHAPNLPYRYQKEKNVSIEDYYE LLYRVFIINNSLEKEQKVYEGAHRAVEIEALTP HSSYCVVAEIYQPMLDRRSQRSEERCVEIP*LV EFGIQQCGNSKAP*EQDDSCLKDLI*NCFCIFLK QYSLLHLGDFFVYPFFYPLYFICKLYLNDIPPE KLKCKDEAENKVFYEIQNFISECNIPNNNLHSS NTAK*KFNNQGIVFKKMLK*FF*NSITD*GGPEA MVFHSLIEPIKLTLL*QFKTSIKVNIFHTFLFY MNILFIYLLLLNIST**IKILF*SLLYVNKNRF WGKKSYDFWIDI*IKTINNKEVCSVQLSLI*KIY *AFLFCLFLFCLVFNPVLEELIFILKIKCNFFS DKEERKPHYSILLAKSVLLVAPSSSLYRRIP*M MVYWELLGSTPYRELSLKLEAHSG*QEKDRCW*V PTETIELDKALQTGPSCSLPLLSRNLVT*GSVW STESCLLHLRLSLHICLRLSF**GDTYQRTFVQ FPMKIAPKLITI*SVLLVICKYSVINGLKNIQKC IGGWRRIRGRARARELVSLLPCMLRKH*FEHRR RD*KKNLL*SLFLNSYYLYFAYYLFCLLSFCGE GDELRVVGWVASK*NFK*HFSECNSVVLKPDLIK QNSFMVVS*KLLDRIKFCLYIVCLALFLLLCLG KCKILYGNHNCHLLHGVRDILSHDFNKSFFCF

Frame 2

HFTTTRYRALVKFSPPLYLCLSFFICNIK*III PIS*TS*ED*QRQNMGKT*HGVP*LLDLIIDTK MALKLPKGRQHLFPLWS*AG*KEHWLPEQSHLQ P*CLNIAF*ASSSVSSLLV*QELSQRMSL*SLRG YNFSPEIFTTFCNGSLGGHLLATAVSILCSTKS CSHAA*KALTRSQVDAGSTFLVTSQAAEHWLNM DRDNGKIKKTVGVLKNSLVTLPVKPQTYRNLITG G*GRPRLGATQNGA*RRGSLPGGKQK*ILQS*I *PKSMALCW*FSMLQIYHIDTKRKKMYL*KITM NYYTEFL*LTIH*KRSKRFMKGLTERLKLKL*HH TPATV*WLKYISPC*TEEVREVKRDVWKFHDLW NLAFSNVEILKLPENRMTRV*RILFKIVFVFS* SNIHCYTLGTSLFIHSFILYISFVNYI*TTFPPK N*NVKMRQRIKCSMKFRTLFLNVTSLITTFILL IQQNKNLTTKE*YLRKC*NNFFKIALQTEAVLK QWFFTLLLSQLN*HCFDNLKLL*R*IFFIHFYFI *IYFLYIYYY*IFLLNESKFCFKVYFM*IRTGF GEKNLMISGLISELKLSTTRKSALYNCPSFKRY IKLFFSVCFCFV*FLILS*KNLSLFSKLNVIFLV TKKKGNLITQSFWPRVSCLWRLPHLYIGGSHE* WFIGNCWGRPHTENSA*SWKHTVGSRRRTGVGR CLQRL*S*TKPSKLAPPAHCLS*VEIW*PKAQCG QQKAAFFT*G*VFIYV*GCLSSEEIHIREHLYN SP*KLLQS**QYSRCF*LYASTQ**MD*KIFRN VLGGGGE*EAEQELENWFPCFPVCSENIDLSIDA ETEKKIYFDLCF*ILIIYILLTTFFAFCPFVER AMN*E*WGGWRVSKISNSILVNAIQ*S*SLT** NKIHLWLFHESY*IGSSFVCILFALLCFCFCA*A SAKYSMEIIIVIFFMVLGIYCHMISINPFFAL