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Sequences

Sequence NM_001004057

AGCCGTTAGCGCCGAGCCCGCCCGGGAGCGGGTCGCCGGCCGCGGCGGGCGCCCCTGCCAGTGAGCCCCTGTCCGAAGTGAGCCACGGCATTGACTCGGG
GCTGCCCGGGGGCAGGGCACTGAGGAGGGAGTTGCGCGCGCGAGGCGAGGGCGATGGGGCCAAGAAGAACCGGGGCGATAGCGCGGCAGCGGTGACAGCT
GGGACCCGCCGCGGTCGGGCTGCCCCCTCCCCTCGCCCCGACCGCTCCCCTGCTGGTGAGGGCCTGCGGAGGCGGCGGCGGCGGCGCCCTTGGTGGCAGT
GGTGGCGGCGGAGCAGCCTCCCGGGATCGTGTCCGGAGCTCGAGGAGAGGGTGGTGCCCGGCGAGCTATGCACGGGGGCGGCGGCGTCTCCTCCTGTTCC
GCCTCCTCAGTCTCCTCGGTCTCGCAGAATCCGCCGGCGGCGGCGGCGCCAGGACATGGAGCTCGAGAACATCGTGGCCAACTCGCTGCTGCTGAAAGCG
CGTCAAGGAGGATATGGCAAAAAAAGTGGTCGTAGTAAAAAATGGAAGGAGATACTGACACTGCCTCCTGTCAGCCAGTGCAGTGAGCTTAGACATTCCA
TTGAAAAGGATTATAGCAGTCTTTGTGACAAGCAACCGATAGGAAGACGTCTCTTCAGGCAGTTCTGTGATACCAAACCCACTCTAAAGAGGCACATTGA
ATTCTTGGATGCAGTGGCAGAATATGAAGTTGCCGATGATGAGGACCGAAGTGATTGTGGACTGTCAATCTTAGATAGATTCTTCAATGATAAGTTGGCA
GCCCCTTTACCAGAAATACCTCCAGATGTTGTGACAGAATGTAGATTGGGACTGAAGGAGGAGAACCCTTCCAAAAAAGCCTTTGAGGAATGTACTAGAG
TTGCCCATAACTACCTAAGAGGGGAACCATTTGAAGAATACCAAGAAAGCTCATATTTTTCTCAGTTTTTACAATGGAAATGGCTGGAAAGGCAACCCGT
AACAAAGAACACATTTAGACATTACAGAGTTCTAGGAAAAGGCGGATTTGGAGAGGTTTGCGCCTGTCAAGTGCGAGCCACAGGAAAAATGTATGCCTGC
AAAAAGCTACAAAAAAAAAGAATAAAGAAGAGGAAAGGTGAAGCTATGGCTCTAAATGAGAAAAGAATTCTGGAGAAAGTGCAAAGTAGATTCGTAGTTA
GTTTAGCCTACGCTTATGAAACCAAAGATGCCTTGTGCTTGGTGCTCACCATTATGAATGGAGGGGATTTGAAGTTTCACATTTACAACCTGGGCAATCC
CGGCTTTGATGAGCAGAGAGCCGTTTTCTATGCTGCAGAGCTGTGTTGCGGCTTGGAAGATTTACAGAGGGAAAGAATTGTATACAGAGACTTGAAGCCT
GAGAATATTCTCCTTGATGATCGTGGACACATCCGGATTTCAGACCTCGGTTTGGCCACAGAGATCCCAGAAGGACAGAGGGTTCGAGGAAGAGTTGGAA
CAGTCGGCTACATGGCACCTGAAGTTGTCAATAATGAAAAGTATACGTTTAGTCCCGATTGGTGGGGACTTGGCTGTCTGATCTATGAAATGATTCAGGG
ACATTCTCCATTCAAAAAATACAAAGAGAAAGTCAAATGGGAGGAGGTCGATCAAAGAATCAAGAATGATACCGAGGAGTATTCTGAGAAGTTTTCAGAG
GATGCCAAATCTATCTGCAGGATGTTACTCACCAAGAATCCAAGCAAGCGGCTGGGCTGCAGGGGCGAGGGAGCGGCTGGGGTGAAGCAGCACCCCGTGT
TCAAGGACATCAACTTCAGGAGGCTGGAGGCAAACATGCTGGAGCCCCCTTTCTGTCCTGATCCTCATGCCGTTTACTGTAAGGACGTCCTGGATATCGA
GCAGTTCTCGGTGGTGAAAGGGATCTACCTGGACACCGCAGATGAAGACTTCTATGCTCGGTTTGCTACCGGGTGTGTCTCCATCCCCTGGCAGAATGAG
GGCTGCCTGACCATGGTCCCCAGTGAGAAGGAAGTGGAACCCAAGCAATGCTGAGCACCCCGGTGCGGACCACAGAGCAGACCCTGGCGCCAGGAAGGAG
CATGTGTTAGCGTCTCGTCCCACCTGGAATTGTAATAAATACATCTAAATAAAACATGCCTTGGGAGTGTACAGAC
  • refseq_GRK4.F1 (forward primer)
  • refseq_GRK4.R1 (reverse primer)
  • Single exon skipping

Frame 0

SR*RRARPGAGRRPRRAPLPVSPCPK*ATALTR
GCPGAGH*GGSCAREARAMGPRRTGAIARQR*QL
GPAAVGLPPPLAPTAPLLVRACGGGGGGALGGS
GGGGAASRDRVRSSRRGWCPASYARGRRRLLLF
RLLSLLGLAESAGGGGARTWSSRTSWPTRCC*KR
VKEDMAKKVVVVKNGRRY*HCLLSASAVSLDIP
LKRIIAVFVTSNR*EDVSSGSSVIPNPL*RGTL
NSWMQWQNMKLPMMRTEVIVDCQS*IDSSMISWQ
PLYQKYLQML*QNVDWD*RRRTLPKKPLRNVLE
LPITT*EGNHLKNTKKAHIFLSFYNGNGWKGNP
*QRTHLDITEF*EKADLERFAPVKCEPQEKCMPA
KSYKKKE*RRGKVKLWL*MRKEFWRKCKVDS*L
V*PTLMKPKMPCAWCSPL*MEGI*SFTFTTWAI
PALMSREPFSMLQSCVAAWKIYRGKELYTET*SL
RIFSLMIVDTSGFQTSVWPQRSQKDRGFEEELE
QSATWHLKLSIMKSIRLVPIGGDLAV*SMK*FR
DILHSKNTKRKSNGRRSIKESRMIPRSILRSFQR
MPNLSAGCYSPRIQASGWAAGARERLG*SSTPC
SRTSTSGGWRQTCWSPLSVLILMPFTVRTSWIS
SSSRW*KGSTWTPQMKTSMLGLLPGVSPSPGRMR
AA*PWSPVRRKWNPSNAEHPGADHRADPGARKE
HVLASRPTWNCNKYI*IKHALGVYR

Frame 1

AVSAEPARERVAGRGGRPCQ*APVRSEPRH*LG
AARGQGTEEGVARARRGRWGQEEPGR*RGSGDS
WDPPRSGCPLPSPRPLPCW*GPAEAAAAAPLVAV
VAAEQPPGIVSGARGEGGARRAMHGGGGVSSCS
ASSVSSVSQNPPAAAAPGHGAREHRGQLAAAES
ASRRIWQKKWS**KMEGDTDTASCQPVQ*A*TFH
*KGL*QSL*QATDRKTSLQAVL*YQTHSKEAH*
ILGCSGRI*SCR**GPK*LWTVNLR*ILQ**VG
SPFTRNTSRCCDRM*IGTEGGEPFQKSL*GMY*S
CP*LPKRGTI*RIPRKLIFFSVFTMEMAGKATR
NKEHI*TLQSSRKRRIWRGLRLSSASHRKNVCL
QKATKKKNKEEER*SYGSK*EKNSGESAK*IRS*
FSLRL*NQRCLVLGAHHYEWRGFEVSHLQPGQS
RL**AESRFLCCRAVLRLGRFTEGKNCIQRLEA
*EYSP**SWTHPDFRPRFGHRDPRRTEGSRKSWN
SRLHGT*SCQ**KVYV*SRLVGTWLSDL*NDSG
TFSIQKIQRESQMGGGRSKNQE*YRGVF*EVFR
GCQIYLQDVTHQESKQAAGLQGRGSGWGEAAPRV
QGHQLQEAGGKHAGAPFLS*SSCRLL*GRPGYR
AVLGGERDLPGHRR*RLLCSVCYRVCLHPLAE*
GLPDHGPQ*EGSGTQAMLSTPVRTTEQTLAPGRS
MC*RLVPPGIVINTSK*NMPWECTD

Frame 2

PLAPSPPGSGSPAAAGAPASEPLSEVSHGIDSG
LPGGRALRRELRARGEGDGAKKNRGDSAAAVTA
GTRRGRAAPSPRPDRSPAGEGLRRRRRRRPWWQ
WWRRSSLPGSCPELEERVVPGELCTGAAASPPVP
PPQSPRSRRIRRRRRRQDMELENIVANSLLLKA
RQGGYGKKSGRSKKWKEILTLPPVSQCSELRHS
IEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIE
FLDAVAEYEVADDEDRSDCGLSILDRFFNDKLA
APLPEIPPDVVTECRLGLKEENPSKKAFEECTR
VAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPV
TKNTFRHYRVLGKGGFGEVCACQVRATGKMYAC
KKLQKKRIKKRKGEAMALNEKRILEKVQSRFVV
SLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNP
GFDEQRAVFYAAELCCGLEDLQRERIVYRDLKP
ENILLDDRGHIRISDLGLATEIPEGQRVRGRVG
TVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQG
HSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSE
DAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPV
FKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIE
QFSVVKGIYLDTADEDFYARFATGCVSIPWQNE
GCLTMVPSEKEVEPKQC*APRCGPQSRPWRQEG
ACVSVSSHLEL**IHLNKTCLGSVQ

Sequence NM_182982

AGCCGTTAGCGCCGAGCCCGCCCGGGAGCGGGTCGCCGGCCGCGGCGGGCGCCCCTGCCAGTGAGCCCCTGTCCGAAGTGAGCCACGGCATTGACTCGGG
GCTGCCCGGGGGCAGGGCACTGAGGAGGGAGTTGCGCGCGCGAGGCGAGGGCGATGGGGCCAAGAAGAACCGGGGCGATAGCGCGGCAGCGGTGACAGCT
GGGACCCGCCGCGGTCGGGCTGCCCCCTCCCCTCGCCCCGACCGCTCCCCTGCTGGTGAGGGCCTGCGGAGGCGGCGGCGGCGGCGCCCTTGGTGGCAGT
GGTGGCGGCGGAGCAGCCTCCCGGGATCGTGTCCGGAGCTCGAGGAGAGGGTGGTGCCCGGCGAGCTATGCACGGGGGCGGCGGCGTCTCCTCCTGTTCC
GCCTCCTCAGTCTCCTCGGTCTCGCAGAATCCGCCGGCGGCGGCGGCGCCAGGACATGGAGCTCGAGAACATCGTGGCCAACTCGCTGCTGCTGAAAGCG
CGTCAAGGAGGATATGGCAAAAAAAGTGGTCGTAGTAAAAAATGGAAGGAGATACTGACACTGCCTCCTGTCAGCCAGTGCAGTGAGCTTAGACATTCCA
TTGAAAAGGATTATAGCAGTCTTTGTGACAAGCAACCGATAGGAAGACGTCTCTTCAGGCAGTTCTGTGATACCAAACCCACTCTAAAGAGGCACATTGA
ATTCTTGGATGCAGTGGCAGAATATGAAGTTGCCGATGATGAGGACCGAAGTGATTGTGGACTGTCAATCTTAGATAGATTCTTCAATGATAAGTTGGCA
GCCCCTTTACCAGAAATACCTCCAGATGTTGTGACAGAATGTAGATTGGGACTGAAGGAGGAGAACCCTTCCAAAAAAGCCTTTGAGGAATGTACTAGAG
TTGCCCATAACTACCTAAGAGGGGAACCATTTGAAGAATACCAAGAAAGCTCATATTTTTCTCAGTTTTTACAATGGAAATGGCTGGAAAGGCAACCCGT
AACAAAGAACACATTTAGACATTACAGAGTTCTAGGAAAAGGCGGATTTGGAGAGGTTTGCGCCTGTCAAGTGCGAGCCACAGGAAAAATGTATGCCTGC
AAAAAGCTACAAAAAAAAAGAATAAAGAAGAGGAAAGGTGAAGCTATGGCTCTAAATGAGAAAAGAATTCTGGAGAAAGTGCAAAGTAGATTCGTAGTTA
GTTTAGCCTACGCTTATGAAACCAAAGATGCCTTGTGCTTGGTGCTCACCATTATGAATGGAGGGGATTTGAAGTTTCACATTTACAACCTGGGCAATCC
CGGCTTTGATGAGCAGAGAGCCGTTTTCTATGCTGCAGAGCTGTGTTGCGGCTTGGAAGATTTACAGAGGGAAAGAATTGTATACAGAGACTTGAAGCCT
GAGAATATTCTCCTTGATGATCGTGGACACATCCGGATTTCAGACCTCGGTTTGGCCACAGAGATCCCAGAAGGACAGAGGGTTCGAGGAAGAGTTGGAA
CAGTCGGCTACATGGCACCTGAAGTTGTCAATAATGAAAAGTATACGTTTAGTCCCGATTGGTGGGGACTTGGCTGTCTGATCTATGAAATGATTCAGGG
ACATTCTCCATTCAAAAAATACAAAGAGAAAGTCAAATGGGAGGAGGTCGATCAAAGAATCAAGAATGATACCGAGGAGTATTCTGAGAAGTTTTCAGAG
GATGCCAAATCTATCTGCAGGATGTTACTCACCAAGAATCCAAGCAAGCGGCTGGGCTGCAGGGGCGAGGGAGCGGCTGGGGTGAAGCAGCACCCCGTGT
TCAAGGACATCAACTTCAGGAGGCTGGAGGCAAACATGCTGGAGCCCCCTTTCTGTCCTGATCCTCATGCCGTTTACTGTAAGGACGTCCTGGATATCGA
GCAGTTCTCGGTGGTGAAAGGGATCTACCTGGACACCGCAGATGAAGACTTCTATGCTCGGTTTGCTACCGGGTGTGTCTCCATCCCCTGGCAGAATGAG
ATGATCGAATCTGGGTGTTTCAAAGACATCAACAAAAGTGAAAGTGAGGAAGCTTTGCCATTAGATCTAGACAAGAACATACATACCCCGGTTTCCAGAC
CAAACAGAGGCTTCTTCTATAGACTCTTCAGAAGAGGGGGCTGCCTGACCATGGTCCCCAGTGAGAAGGAAGTGGAACCCAAGCAATGCTGAGCACCCCG
GTGCGGACCACAGAGCAGACCCTGGCGCCAGGAAGGAGCATGTGTTAGCGTCTCGTCCCACCTGGAATTGTAATAAATACATCTAAATAAAACATGCCTT
GGGAGTGTACAGAC
  • refseq_GRK4.F1 (forward primer)
  • refseq_GRK4.R1 (reverse primer)
  • Single exon skipping

Frame 0

SR*RRARPGAGRRPRRAPLPVSPCPK*ATALTR
GCPGAGH*GGSCAREARAMGPRRTGAIARQR*QL
GPAAVGLPPPLAPTAPLLVRACGGGGGGALGGS
GGGGAASRDRVRSSRRGWCPASYARGRRRLLLF
RLLSLLGLAESAGGGGARTWSSRTSWPTRCC*KR
VKEDMAKKVVVVKNGRRY*HCLLSASAVSLDIP
LKRIIAVFVTSNR*EDVSSGSSVIPNPL*RGTL
NSWMQWQNMKLPMMRTEVIVDCQS*IDSSMISWQ
PLYQKYLQML*QNVDWD*RRRTLPKKPLRNVLE
LPITT*EGNHLKNTKKAHIFLSFYNGNGWKGNP
*QRTHLDITEF*EKADLERFAPVKCEPQEKCMPA
KSYKKKE*RRGKVKLWL*MRKEFWRKCKVDS*L
V*PTLMKPKMPCAWCSPL*MEGI*SFTFTTWAI
PALMSREPFSMLQSCVAAWKIYRGKELYTET*SL
RIFSLMIVDTSGFQTSVWPQRSQKDRGFEEELE
QSATWHLKLSIMKSIRLVPIGGDLAV*SMK*FR
DILHSKNTKRKSNGRRSIKESRMIPRSILRSFQR
MPNLSAGCYSPRIQASGWAAGARERLG*SSTPC
SRTSTSGGWRQTCWSPLSVLILMPFTVRTSWIS
SSSRW*KGSTWTPQMKTSMLGLLPGVSPSPGRMR
*SNLGVSKTSTKVKVRKLCH*I*TRTYIPRFPD
QTEASSIDSSEEGAA*PWSPVRRKWNPSNAEHP
GADHRADPGARKEHVLASRPTWNCNKYI*IKHAL
GVYR

Frame 1

AVSAEPARERVAGRGGRPCQ*APVRSEPRH*LG
AARGQGTEEGVARARRGRWGQEEPGR*RGSGDS
WDPPRSGCPLPSPRPLPCW*GPAEAAAAAPLVAV
VAAEQPPGIVSGARGEGGARRAMHGGGGVSSCS
ASSVSSVSQNPPAAAAPGHGAREHRGQLAAAES
ASRRIWQKKWS**KMEGDTDTASCQPVQ*A*TFH
*KGL*QSL*QATDRKTSLQAVL*YQTHSKEAH*
ILGCSGRI*SCR**GPK*LWTVNLR*ILQ**VG
SPFTRNTSRCCDRM*IGTEGGEPFQKSL*GMY*S
CP*LPKRGTI*RIPRKLIFFSVFTMEMAGKATR
NKEHI*TLQSSRKRRIWRGLRLSSASHRKNVCL
QKATKKKNKEEER*SYGSK*EKNSGESAK*IRS*
FSLRL*NQRCLVLGAHHYEWRGFEVSHLQPGQS
RL**AESRFLCCRAVLRLGRFTEGKNCIQRLEA
*EYSP**SWTHPDFRPRFGHRDPRRTEGSRKSWN
SRLHGT*SCQ**KVYV*SRLVGTWLSDL*NDSG
TFSIQKIQRESQMGGGRSKNQE*YRGVF*EVFR
GCQIYLQDVTHQESKQAAGLQGRGSGWGEAAPRV
QGHQLQEAGGKHAGAPFLS*SSCRLL*GRPGYR
AVLGGERDLPGHRR*RLLCSVCYRVCLHPLAE*
DDRIWVFQRHQQK*K*GSFAIRSRQEHTYPGFQT
KQRLLL*TLQKRGLPDHGPQ*EGSGTQAMLSTP
VRTTEQTLAPGRSMC*RLVPPGIVINTSK*NMP
WECTD

Frame 2

PLAPSPPGSGSPAAAGAPASEPLSEVSHGIDSG
LPGGRALRRELRARGEGDGAKKNRGDSAAAVTA
GTRRGRAAPSPRPDRSPAGEGLRRRRRRRPWWQ
WWRRSSLPGSCPELEERVVPGELCTGAAASPPVP
PPQSPRSRRIRRRRRRQDMELENIVANSLLLKA
RQGGYGKKSGRSKKWKEILTLPPVSQCSELRHS
IEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRHIE
FLDAVAEYEVADDEDRSDCGLSILDRFFNDKLA
APLPEIPPDVVTECRLGLKEENPSKKAFEECTR
VAHNYLRGEPFEEYQESSYFSQFLQWKWLERQPV
TKNTFRHYRVLGKGGFGEVCACQVRATGKMYAC
KKLQKKRIKKRKGEAMALNEKRILEKVQSRFVV
SLAYAYETKDALCLVLTIMNGGDLKFHIYNLGNP
GFDEQRAVFYAAELCCGLEDLQRERIVYRDLKP
ENILLDDRGHIRISDLGLATEIPEGQRVRGRVG
TVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMIQG
HSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFSE
DAKSICRMLLTKNPSKRLGCRGEGAAGVKQHPV
FKDINFRRLEANMLEPPFCPDPHAVYCKDVLDIE
QFSVVKGIYLDTADEDFYARFATGCVSIPWQNE
MIESGCFKDINKSESEEALPLDLDKNIHTPVSR
PNRGFFYRLFRRGGCLTMVPSEKEVEPKQC*APR
CGPQSRPWRQEGACVSVSSHLEL**IHLNKTCL
GSVQ

Sequence NM_001004056

AGCCGTTAGCGCCGAGCCCGCCCGGGAGCGGGTCGCCGGCCGCGGCGGGCGCCCCTGCCAGTGAGCCCCTGTCCGAAGTGAGCCACGGCATTGACTCGGG
GCTGCCCGGGGGCAGGGCACTGAGGAGGGAGTTGCGCGCGCGAGGCGAGGGCGATGGGGCCAAGAAGAACCGGGGCGATAGCGCGGCAGCGGTGACAGCT
GGGACCCGCCGCGGTCGGGCTGCCCCCTCCCCTCGCCCCGACCGCTCCCCTGCTGGTGAGGGCCTGCGGAGGCGGCGGCGGCGGCGCCCTTGGTGGCAGT
GGTGGCGGCGGAGCAGCCTCCCGGGATCGTGTCCGGAGCTCGAGGAGAGGGTGGTGCCCGGCGAGCTATGCACGGGGGCGGCGGCGTCTCCTCCTGTTCC
GCCTCCTCAGTCTCCTCGGTCTCGCAGAATCCGCCGGCGGCGGCGGCGCCAGGACATGGAGCTCGAGAACATCGTGGCCAACTCGCTGCTGCTGAAAGCG
CGTCAAGAAAAGGATTATAGCAGTCTTTGTGACAAGCAACCGATAGGAAGACGTCTCTTCAGGCAGTTCTGTGATACCAAACCCACTCTAAAGAGGCACA
TTGAATTCTTGGATGCAGTGGCAGAATATGAAGTTGCCGATGATGAGGACCGAAGTGATTGTGGACTGTCAATCTTAGATAGATTCTTCAATGATAAGTT
GGCAGCCCCTTTACCAGAAATACCTCCAGATGTTGTGACAGAATGTAGATTGGGACTGAAGGAGGAGAACCCTTCCAAAAAAGCCTTTGAGGAATGTACT
AGAGTTGCCCATAACTACCTAAGAGGGGAACCATTTGAAGAATACCAAGAAAGCTCATATTTTTCTCAGTTTTTACAATGGAAATGGCTGGAAAGGCAAC
CCGTAACAAAGAACACATTTAGACATTACAGAGTTCTAGGAAAAGGCGGATTTGGAGAGGTTTGCGCCTGTCAAGTGCGAGCCACAGGAAAAATGTATGC
CTGCAAAAAGCTACAAAAAAAAAGAATAAAGAAGAGGAAAGGTGAAGCTATGGCTCTAAATGAGAAAAGAATTCTGGAGAAAGTGCAAAGTAGATTCGTA
GTTAGTTTAGCCTACGCTTATGAAACCAAAGATGCCTTGTGCTTGGTGCTCACCATTATGAATGGAGGGGATTTGAAGTTTCACATTTACAACCTGGGCA
ATCCCGGCTTTGATGAGCAGAGAGCCGTTTTCTATGCTGCAGAGCTGTGTTGCGGCTTGGAAGATTTACAGAGGGAAAGAATTGTATACAGAGACTTGAA
GCCTGAGAATATTCTCCTTGATGATCGTGGACACATCCGGATTTCAGACCTCGGTTTGGCCACAGAGATCCCAGAAGGACAGAGGGTTCGAGGAAGAGTT
GGAACAGTCGGCTACATGGCACCTGAAGTTGTCAATAATGAAAAGTATACGTTTAGTCCCGATTGGTGGGGACTTGGCTGTCTGATCTATGAAATGATTC
AGGGACATTCTCCATTCAAAAAATACAAAGAGAAAGTCAAATGGGAGGAGGTCGATCAAAGAATCAAGAATGATACCGAGGAGTATTCTGAGAAGTTTTC
AGAGGATGCCAAATCTATCTGCAGGATGTTACTCACCAAGAATCCAAGCAAGCGGCTGGGCTGCAGGGGCGAGGGAGCGGCTGGGGTGAAGCAGCACCCC
GTGTTCAAGGACATCAACTTCAGGAGGCTGGAGGCAAACATGCTGGAGCCCCCTTTCTGTCCTGATCCTCATGCCGTTTACTGTAAGGACGTCCTGGATA
TCGAGCAGTTCTCGGTGGTGAAAGGGATCTACCTGGACACCGCAGATGAAGACTTCTATGCTCGGTTTGCTACCGGGTGTGTCTCCATCCCCTGGCAGAA
TGAGATGATCGAATCTGGGTGTTTCAAAGACATCAACAAAAGTGAAAGTGAGGAAGCTTTGCCATTAGATCTAGACAAGAACATACATACCCCGGTTTCC
AGACCAAACAGAGGCTTCTTCTATAGACTCTTCAGAAGAGGGGGCTGCCTGACCATGGTCCCCAGTGAGAAGGAAGTGGAACCCAAGCAATGCTGAGCAC
CCCGGTGCGGACCACAGAGCAGACCCTGGCGCCAGGAAGGAGCATGTGTTAGCGTCTCGTCCCACCTGGAATTGTAATAAATACATCTAAATAAAACATG
CCTTGGGAGTGTACAGAC
  • refseq_GRK4.F1 (forward primer)
  • refseq_GRK4.R1 (reverse primer)
  • Single exon skipping

Frame 0

SR*RRARPGAGRRPRRAPLPVSPCPK*ATALTR
GCPGAGH*GGSCAREARAMGPRRTGAIARQR*QL
GPAAVGLPPPLAPTAPLLVRACGGGGGGALGGS
GGGGAASRDRVRSSRRGWCPASYARGRRRLLLF
RLLSLLGLAESAGGGGARTWSSRTSWPTRCC*KR
VKKRIIAVFVTSNR*EDVSSGSSVIPNPL*RGT
LNSWMQWQNMKLPMMRTEVIVDCQS*IDSSMIS
WQPLYQKYLQML*QNVDWD*RRRTLPKKPLRNVL
ELPITT*EGNHLKNTKKAHIFLSFYNGNGWKGN
P*QRTHLDITEF*EKADLERFAPVKCEPQEKCM
PAKSYKKKE*RRGKVKLWL*MRKEFWRKCKVDS*
LV*PTLMKPKMPCAWCSPL*MEGI*SFTFTTWA
IPALMSREPFSMLQSCVAAWKIYRGKELYTET*
SLRIFSLMIVDTSGFQTSVWPQRSQKDRGFEEEL
EQSATWHLKLSIMKSIRLVPIGGDLAV*SMK*F
RDILHSKNTKRKSNGRRSIKESRMIPRSILRSF
QRMPNLSAGCYSPRIQASGWAAGARERLG*SSTP
CSRTSTSGGWRQTCWSPLSVLILMPFTVRTSWI
SSSSRW*KGSTWTPQMKTSMLGLLPGVSPSPGR
MR*SNLGVSKTSTKVKVRKLCH*I*TRTYIPRFP
DQTEASSIDSSEEGAA*PWSPVRRKWNPSNAEH
PGADHRADPGARKEHVLASRPTWNCNKYI*IKH
ALGVYR

Frame 1

AVSAEPARERVAGRGGRPCQ*APVRSEPRH*LG
AARGQGTEEGVARARRGRWGQEEPGR*RGSGDS
WDPPRSGCPLPSPRPLPCW*GPAEAAAAAPLVAV
VAAEQPPGIVSGARGEGGARRAMHGGGGVSSCS
ASSVSSVSQNPPAAAAPGHGAREHRGQLAAAES
ASRKGL*QSL*QATDRKTSLQAVL*YQTHSKEAH
*ILGCSGRI*SCR**GPK*LWTVNLR*ILQ**V
GSPFTRNTSRCCDRM*IGTEGGEPFQKSL*GMY
*SCP*LPKRGTI*RIPRKLIFFSVFTMEMAGKAT
RNKEHI*TLQSSRKRRIWRGLRLSSASHRKNVC
LQKATKKKNKEEER*SYGSK*EKNSGESAK*IR
S*FSLRL*NQRCLVLGAHHYEWRGFEVSHLQPGQ
SRL**AESRFLCCRAVLRLGRFTEGKNCIQRLE
A*EYSP**SWTHPDFRPRFGHRDPRRTEGSRKS
WNSRLHGT*SCQ**KVYV*SRLVGTWLSDL*NDS
GTFSIQKIQRESQMGGGRSKNQE*YRGVF*EVF
RGCQIYLQDVTHQESKQAAGLQGRGSGWGEAAP
RVQGHQLQEAGGKHAGAPFLS*SSCRLL*GRPGY
RAVLGGERDLPGHRR*RLLCSVCYRVCLHPLAE
*DDRIWVFQRHQQK*K*GSFAIRSRQEHTYPGF
QTKQRLLL*TLQKRGLPDHGPQ*EGSGTQAMLST
PVRTTEQTLAPGRSMC*RLVPPGIVINTSK*NM
PWECTD

Frame 2

PLAPSPPGSGSPAAAGAPASEPLSEVSHGIDSG
LPGGRALRRELRARGEGDGAKKNRGDSAAAVTA
GTRRGRAAPSPRPDRSPAGEGLRRRRRRRPWWQ
WWRRSSLPGSCPELEERVVPGELCTGAAASPPVP
PPQSPRSRRIRRRRRRQDMELENIVANSLLLKA
RQEKDYSSLCDKQPIGRRLFRQFCDTKPTLKRH
IEFLDAVAEYEVADDEDRSDCGLSILDRFFNDKL
AAPLPEIPPDVVTECRLGLKEENPSKKAFEECT
RVAHNYLRGEPFEEYQESSYFSQFLQWKWLERQ
PVTKNTFRHYRVLGKGGFGEVCACQVRATGKMYA
CKKLQKKRIKKRKGEAMALNEKRILEKVQSRFV
VSLAYAYETKDALCLVLTIMNGGDLKFHIYNLG
NPGFDEQRAVFYAAELCCGLEDLQRERIVYRDLK
PENILLDDRGHIRISDLGLATEIPEGQRVRGRV
GTVGYMAPEVVNNEKYTFSPDWWGLGCLIYEMI
QGHSPFKKYKEKVKWEEVDQRIKNDTEEYSEKFS
EDAKSICRMLLTKNPSKRLGCRGEGAAGVKQHP
VFKDINFRRLEANMLEPPFCPDPHAVYCKDVLD
IEQFSVVKGIYLDTADEDFYARFATGCVSIPWQN
EMIESGCFKDINKSESEEALPLDLDKNIHTPVS
RPNRGFFYRLFRRGGCLTMVPSEKEVEPKQC*A
PRCGPQSRPWRQEGACVSVSSHLEL**IHLNKTC
LGSVQ

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