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Sequences

Sequence NM_021956

GGTTGTTCCTTGGCGCAGTGAGTGAAGAACATGCAGCGATTGCTAATGGGTTTGGGAAGCGGAGACTCCTTCCTCTCTCTATGACCATGCCGTGATCGTG
TCTGCGGTCACCACTCGACGCATCCTCATTTCTACCCGAACCCAGGAGCCGAACGCTAGATCGGGGAAGTGGGTGCCGTGCGTGTGGGCACAGAAACACC
ATGAAGATTATTTTCCCGATTCTAAGTAATCCAGTCTTCAGGCGCACCGTTAAACTCCTGCTCTGTTTACTGTGGATTGGATATTCTCAAGGAACCACAC
ATGTATTAAGATTTGGTGGTATTTTTGAATATGTGGAATCTGGCCCAATGGGAGCTGAGGAACTTGCATTCAGATTTGCTGTGAACACAATTAACAGAAA
CAGAACATTGCTACCCAATACTACCCTTACCTATGATACCCAGAAGATAAACCTTTATGATAGTTTTGAAGCATCCAAGAAAGCCTGTGATCAGCTGTCT
CTTGGGGTGGCTGCCATCTTCGGGCCTTCACACAGCTCATCAGCAAACGCAGTGCAGTCCATCTGCAATGCTCTGGGAGTTCCCCACATACAGACCCGCT
GGAAGCACCAGGTGTCAGACAACAAAGATTCCTTCTATGTCAGTCTCTACCCAGACTTCTCTTCACTCAGCCGTGCCATTTTAGACCTGGTGCAGTTTTT
CAAGTGGAAAACCGTCACGGTTGTGTATGATGACAGCACTGGTCTCATTCGTTTGCAAGAGCTCATCAAAGCTCCATCAAGGTATAATCTTCGACTCAAA
ATTCGTCAGTTACCTGCTGATACAAAGGATGCAAAACCCTTACTAAAAGAAATGAAAAGAGGCAAGGAGTTTCATGTAATCTTTGATTGTAGCCATGAAA
TGGCAGCAGGCATTTTAAAACAGGCATTAGCTATGGGAATGATGACAGAATACTATCATTATATCTTTACCACTCTGGACCTCTTTGCTCTTGATGTTGA
GCCCTACCGATACAGTGGTGTTAACATGACAGGGTTCAGAATATTAAATACAGAAAATACCCAAGTCTCCTCCATCATTGAAAAGTGGTCGATGGAACGA
TTGCAGGCACCTCCGAAACCCGATTCAGGTTTGCTGGATGGATTTATGACGACTGATGCTGCTCTAATGTATGATGCTGTGCATGTGGTGTCTGTGGCCG
TTCAACAGTTTCCCCAGATGACAGTCAGTTCCTTGCAGTGTAATCGACATAAACCCTGGCGCTTCGGGACCCGCTTTATGAGTCTAATTAAAGAGGCACA
TTGGGAAGGCCTCACAGGCAGAATAACTTTCAACAAAACCAATGGCTTGAGAACAGATTTTGATTTGGATGTGATCAGTCTGAAGGAAGAAGGTCTAGAA
AAGATTGGAACGTGGGATCCAGCCAGTGGCCTGAATATGACAGAAAGTCAAAAGGGAAAGCCAGCGAACATCACAGATTCCTTATCCAATCGTTCTTTGA
TTGTTACCACCATTTTGGAAGAGCCTTATGTCCTTTTTAAGAAGTCTGACAAACCTCTCTATGGTAATGATCGATTTGAAGGCTATTGCATTGATCTCCT
CAGAGAGTTATCTACAATCCTTGGCTTTACATATGAAATTAGACTTGTGGAAGATGGGAAATATGGAGCCCAGGATGATGCCAATGGACAATGGAATGGA
ATGGTTCGTGAACTAATTGATCATAAAGCTGACCTTGCAGTTGCTCCACTGGCTATTACCTATGTTCGAGAGAAGGTCATCGACTTTTCCAAGCCCTTTA
TGACACTTGGAATAAGTATTTTGTACCGCAAGCCCAATGGTACAAACCCAGGCGTCTTCTCCTTCCTGAATCCTCTCTCCCCTGATATCTGGATGTATAT
TCTGCTGGCTTACTTGGGTGTCAGTTGTGTGCTCTTTGTCATAGCCAGGTTTAGTCCTTATGAGTGGTATAATCCACACCCTTGCAACCCTGACTCAGAC
GTGGTGGAAAACAATTTTACCTTGCTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGTTCTGAGCTCATGCCCAAAGCACTGTCCACCA
GGATAGTGGGAGGCATTTGGTGGTTTTTCACACTTATCATCATTTCTTCGTATACTGCTAACTTAGCCGCCTTTCTGACAGTGGAACGCATGGAATCCCC
TATTGACTCTGCTGATGATTTAGCTAAACAAACCAAGATAGAATATGGAGCAGTAGAGGATGGTGCAACCATGACTTTTTTCAAGAAATCAAAAATCTCC
ACGTATGACAAAATGTGGGCCTTTATGAGTAGCAGAAGGCAGTCAGTGCTGGTCAAAAGTAATGAAGAAGGAATCCAGCGAGTCCTCACCTCTGATTATG
CTTTCCTAATGGAGTCAACAACCATCGAGTTTGTTACCCAGCGGAACTGTAACCTGACACAGATTGGCGGCCTTATAGACTCTAAAGGTTATGGCGTTGG
CACTCCCATGGGTTCTCCATATCGAGACAAAATTACCATAGCAATTCTTCAGCTGCAAGAGGAAGGCAAACTGCATATGATGAAGGAGAAATGGTGGAGG
GGCAATGGTTGCCCAGAAGAGGAGAGCAAAGAGGCCAGTGCCCTGGGGGTTCAGAATATTGGTGGCATCTTCATTGTTCTGGCAGCCGGCTTGGTGCTTT
CAGTTT
TTGTGGCAGTGGGAGAATTTTTATACAAATCCAAAAAAAACGCTCAATTGGAAAAGAGGTCCTTCTGTAGTGCCATGGTAGAAGAATTGAGGAT
GTCCCTGAAGTGCCAGCGTCGGTTAAAACATAAGCCACAGGCCCCAGTTATTGTGAAAACAGAAGAAGTTATCAACATGCACACATTTAACGACAGAAGG
TTGCCAGGTAAAGAAACCATGGCATAAAGCTGGGAGGCCAAACACCCAAGCACAAACTGTCGTCTTTTTCCAAACAATTTAGCCAGAATGTTTCCTGTGG
A
AATATGCAACCTGTGCAAAATAAAATGAGTTACCTCATGCCGCTGTGTCTATGAACTAGAGACTCTGTGATCTAAGCAGTTGCAATGATCAGACTTGAT
TTACAAGCATCATGGATCAACCAAGTTACACGGGGTTACACTGTTAATCATGGGTTCCTCCCTTCTTCTGAGTGAATGTTAACATGCGCATTTTGTGGCT
GATTTCAAATGCAGTCCAGTGAGAAATTACAGGTTCCTTTTGAAGCTCAACTGTTGCCAGGAGATGGAATATCAATGCCCAACAGGGCAACCAATAAAAG
TGTCACTAAGAATATAAATATT
  • refseq_GRIK2.F1 (forward primer)
  • refseq_GRIK2.R1 (reverse primer)
  • Single exon skipping

Frame 0

GCSLAQ*VKNMQRLLMGLGSGDSFLSL*PCRDR
VCGHHSTHPHFYPNPGAER*IGEVGAVRVGTETP
*RLFSRF*VIQSSGAPLNSCSVYCGLDILKEPH
MY*DLVVFLNMWNLAQWELRNLHSDLL*TQLTE
TEHCYPILPLPMIPRR*TFMIVLKHPRKPVISCL
LGWLPSSGLHTAHQQTQCSPSAMLWEFPTYRPA
GSTRCQTTKIPSMSVSTQTSLHSAVPF*TWCSF
SSGKPSRLCMMTALVSFVCKSSSKLHQGIIFDSK
FVSYLLIQRMQNPY*KK*KEARSFM*SLIVAMK
WQQAF*NRH*LWE**QNTIIISLPLWTSLLLML
SPTDTVVLT*QGSEY*IQKIPKSPPSLKSGRWND
CRHLRNPIQVCWMDL*RLMLL*CMMLCMWCLWP
FNSFPR*QSVPCSVIDINPGASGPAL*V*LKRH
IGKASQAE*LSTKPMA*EQILIWM*SV*RKKV*K
RLERGIQPVA*I*QKVKRESQRTSQIPYPIVL*
LLPPFWKSLMSFLRSLTNLSMVMIDLKAIALIS
SESYLQSLALHMKLDLWKMGNMEPRMMPMDNGME
WFVN*LIIKLTLQLLHWLLPMFERRSSTFPSPL
*HLE*VFCTASPMVQTQASSPS*ILSPLISGCI
FCWLTWVSVVCSLS*PGLVLMSGIIHTLATLTQT
WWKTILPC*IVSGLELELSCSKVLSSCPKHCPP
G*WEAFGGFSHLSSFLRILLT*PPF*QWNAWNP
LLTLLMI*LNKPR*NMEQ*RMVQP*LFSRNQKSP
RMTKCGPL*VAEGSQCWSKVMKKESSESSPLIM
LS*WSQQPSSLLPSGTVT*HRLAAL*TLKVMAL
ALPWVLHIETKLP*QFFSCKRKANCI**RRNGGG
AMVAQKRRAKRPVPWGFRILVASSLFWQPAWCF
QF
LWQWENFYTNPKKTLNWKRGPSVVPW*KN*G
CP*SASVG*NISHRPQLL*KQKKLSTCTHLTTEG
CQVKKPWHKAGRPNTQAQTVVFFQTI*PECFLW
KYATCAK*NELPHAAVSMN*RLCDLSSCNDQT*
FTSIMDQPSYTGLHC*SWVPPFF*VNVNMRILWL
ISNAVQ*EITGSF*SSTVARRWNINAQQGNQ*K
CH*EYKY

Frame 1

VVPWRSE*RTCSDC*WVWEAETPSSLYDHAVIV
SAVTTRRILISTRTQEPNARSGKWVPCVWAQKH
HEDYFPDSK*SSLQAHR*TPALFTVDWIFSRNHT
CIKIWWYF*ICGIWPNGS*GTCIQICCEHN*QK
QNIATQYYPYL*YPEDKPL**F*SIQESL*SAV
SWGGCHLRAFTQLISKRSAVHLQCSGSSPHTDPL
EAPGVRQQRFLLCQSLPRLLFTQPCHFRPGAVF
QVENRHGCV**QHWSHSFARAHQSSIKV*SSTQ
NSSVTC*YKGCKTLTKRNEKRQGVSCNL*L*P*N
GSRHFKTGISYGNDDRILSLYLYHSGPLCS*C*
ALPIQWC*HDRVQNIKYRKYPSLLHH*KVVDGT
IAGTSETRFRFAGWIYDD*CCSNV*CCACGVCGR
STVSPDDSQFLAV*ST*TLALRDPLYESN*RGT
LGRPHRQNNFQQNQWLENRF*FGCDQSEGRRSR
KDWNVGSSQWPEYDRKSKGKASEHHRFLIQSFFD
CYHHFGRALCPF*EV*QTSLW**SI*RLLH*SP
QRVIYNPWLYI*N*TCGRWEIWSPG*CQWTMEW
NGS*TN*S*S*PCSCSTGYYLCSREGHRLFQALY
DTWNKYFVPQAQWYKPRRLLLPESSLP*YLDVY
SAGLLGCQLCALCHSQV*SL*VV*STPLQP*LR
RGGKQFYLAK*FLVWSWSSHAARF*AHAQSTVHQ
DSGRHLVVFHTYHHFFVYC*LSRLSDSGTHGIP
Y*LC**FS*TNQDRIWSSRGWCNHDFFQEIKNL
HV*QNVGLYE*QKAVSAGQK**RRNPASPHL*LC
FPNGVNNHRVCYPAEL*PDTDWRPYRL*RLWRW
HSHGFSISRQNYHSNSSAARGRQTAYDEGEMVE
GQWLPRRGEQRGQCPGGSEYWWHLHCSGSRLGAF
SF
CGSGRIFIQIQKKRSIGKEVLL*CHGRRIED
VPEVPASVKT*ATGPSYCENRRSYQHAHI*RQK
VAR*RNHGIKLGGQTPKHKLSSFSKQFSQNVSCG
NMQPVQNKMSYLMPLCL*TRDSVI*AVAMIRLD
LQASWINQVTRGYTVNHGFLPSSE*MLTCAFCG
*FQMQSSEKLQVPFEAQLLPGDGISMPNRATNKS
VTKNINI

Frame 2

LFLGAVSEEHAAIANGFGKRRLLPLSMTMP*SC
LRSPLDASSFLPEPRSRTLDRGSGCRACGHRNT
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTT
HVLRFGGIFEYVESGPMGAEELAFRFAVNTINRN
RTLLPNTTLTYDTQKINLYDSFEASKKACDQLS
LGVAAIFGPSHSSSANAVQSICNALGVPHIQTR
WKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFF
KWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLK
IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHE
MAAGILKQALAMGMMTEYYHYIFTTLDLFALDVE
PYRYSGVNMTGFRILNTENTQVSSIIEKWSMER
LQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVA
VQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAH
WEGLTGRITFNKTNGLRTDFDLDVISLKEEGLE
KIGTWDPASGLNMTESQKGKPANITDSLSNRSL
IVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLL
RELSTILGFTYEIRLVEDGKYGAQDDANGQWNG
MVRELIDHKADLAVAPLAITYVREKVIDFSKPF
MTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYI
LLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSD
VVENNFTLLNSFWFGVGALMQQGSELMPKALST
RIVGGIWWFFTLIIISSYTANLAAFLTVERMESP
IDSADDLAKQTKIEYGAVEDGATMTFFKKSKIS
TYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDY
AFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVG
TPMGSPYRDKITIAILQLQEEGKLHMMKEKWWR
GNGCPEEESKEASALGVQNIGGIFIVLAAGLVL
SV
FVAVGEFLYKSKKNAQLEKRSFCSAMVEELRM
SLKCQRRLKHKPQAPVIVKTEEVINMHTFNDRR
LPGKETMA*SWEAKHPSTNCRLFPNNLARMFPV
E
ICNLCKIK*VTSCRCVYELETL*SKQLQ*SDLI
YKHHGSTKLHGVTLLIMGSSLLLSEC*HAHFVA
DFKCSPVRNYRFLLKLNCCQEMEYQCPTGQPIK
VSLRI*I

Sequence NM_175768

GGTTGTTCCTTGGCGCAGTGAGTGAAGAACATGCAGCGATTGCTAATGGGTTTGGGAAGCGGAGACTCCTTCCTCTCTCTATGACCATGCCGTGATCGTG
TCTGCGGTCACCACTCGACGCATCCTCATTTCTACCCGAACCCAGGAGCCGAACGCTAGATCGGGGAAGTGGGTGCCGTGCGTGTGGGCACAGAAACACC
ATGAAGATTATTTTCCCGATTCTAAGTAATCCAGTCTTCAGGCGCACCGTTAAACTCCTGCTCTGTTTACTGTGGATTGGATATTCTCAAGGAACCACAC
ATGTATTAAGATTTGGTGGTATTTTTGAATATGTGGAATCTGGCCCAATGGGAGCTGAGGAACTTGCATTCAGATTTGCTGTGAACACAATTAACAGAAA
CAGAACATTGCTACCCAATACTACCCTTACCTATGATACCCAGAAGATAAACCTTTATGATAGTTTTGAAGCATCCAAGAAAGCCTGTGATCAGCTGTCT
CTTGGGGTGGCTGCCATCTTCGGGCCTTCACACAGCTCATCAGCAAACGCAGTGCAGTCCATCTGCAATGCTCTGGGAGTTCCCCACATACAGACCCGCT
GGAAGCACCAGGTGTCAGACAACAAAGATTCCTTCTATGTCAGTCTCTACCCAGACTTCTCTTCACTCAGCCGTGCCATTTTAGACCTGGTGCAGTTTTT
CAAGTGGAAAACCGTCACGGTTGTGTATGATGACAGCACTGGTCTCATTCGTTTGCAAGAGCTCATCAAAGCTCCATCAAGGTATAATCTTCGACTCAAA
ATTCGTCAGTTACCTGCTGATACAAAGGATGCAAAACCCTTACTAAAAGAAATGAAAAGAGGCAAGGAGTTTCATGTAATCTTTGATTGTAGCCATGAAA
TGGCAGCAGGCATTTTAAAACAGGCATTAGCTATGGGAATGATGACAGAATACTATCATTATATCTTTACCACTCTGGACCTCTTTGCTCTTGATGTTGA
GCCCTACCGATACAGTGGTGTTAACATGACAGGGTTCAGAATATTAAATACAGAAAATACCCAAGTCTCCTCCATCATTGAAAAGTGGTCGATGGAACGA
TTGCAGGCACCTCCGAAACCCGATTCAGGTTTGCTGGATGGATTTATGACGACTGATGCTGCTCTAATGTATGATGCTGTGCATGTGGTGTCTGTGGCCG
TTCAACAGTTTCCCCAGATGACAGTCAGTTCCTTGCAGTGTAATCGACATAAACCCTGGCGCTTCGGGACCCGCTTTATGAGTCTAATTAAAGAGGCACA
TTGGGAAGGCCTCACAGGCAGAATAACTTTCAACAAAACCAATGGCTTGAGAACAGATTTTGATTTGGATGTGATCAGTCTGAAGGAAGAAGGTCTAGAA
AAGATTGGAACGTGGGATCCAGCCAGTGGCCTGAATATGACAGAAAGTCAAAAGGGAAAGCCAGCGAACATCACAGATTCCTTATCCAATCGTTCTTTGA
TTGTTACCACCATTTTGGAAGAGCCTTATGTCCTTTTTAAGAAGTCTGACAAACCTCTCTATGGTAATGATCGATTTGAAGGCTATTGCATTGATCTCCT
CAGAGAGTTATCTACAATCCTTGGCTTTACATATGAAATTAGACTTGTGGAAGATGGGAAATATGGAGCCCAGGATGATGCCAATGGACAATGGAATGGA
ATGGTTCGTGAACTAATTGATCATAAAGCTGACCTTGCAGTTGCTCCACTGGCTATTACCTATGTTCGAGAGAAGGTCATCGACTTTTCCAAGCCCTTTA
TGACACTTGGAATAAGTATTTTGTACCGCAAGCCCAATGGTACAAACCCAGGCGTCTTCTCCTTCCTGAATCCTCTCTCCCCTGATATCTGGATGTATAT
TCTGCTGGCTTACTTGGGTGTCAGTTGTGTGCTCTTTGTCATAGCCAGGTTTAGTCCTTATGAGTGGTATAATCCACACCCTTGCAACCCTGACTCAGAC
GTGGTGGAAAACAATTTTACCTTGCTAAATAGTTTCTGGTTTGGAGTTGGAGCTCTCATGCAGCAAGGTTCTGAGCTCATGCCCAAAGCACTGTCCACCA
GGATAGTGGGAGGCATTTGGTGGTTTTTCACACTTATCATCATTTCTTCGTATACTGCTAACTTAGCCGCCTTTCTGACAGTGGAACGCATGGAATCCCC
TATTGACTCTGCTGATGATTTAGCTAAACAAACCAAGATAGAATATGGAGCAGTAGAGGATGGTGCAACCATGACTTTTTTCAAGAAATCAAAAATCTCC
ACGTATGACAAAATGTGGGCCTTTATGAGTAGCAGAAGGCAGTCAGTGCTGGTCAAAAGTAATGAAGAAGGAATCCAGCGAGTCCTCACCTCTGATTATG
CTTTCCTAATGGAGTCAACAACCATCGAGTTTGTTACCCAGCGGAACTGTAACCTGACACAGATTGGCGGCCTTATAGACTCTAAAGGTTATGGCGTTGG
CACTCCCATGGGTTCTCCATATCGAGACAAAATTACCATAGCAATTCTTCAGCTGCAAGAGGAAGGCAAACTGCATATGATGAAGGAGAAATGGTGGAGG
GGCAATGGTTGCCCAGAAGAGGAGAGCAAAGAGGCCAGTGCCCTGGGGGTTCAGAATATTGGTGGCATCTTCATTGTTCTGGCAGCCGGCTTGGTGCTTT
CAGTTT
TTGTGGCAGTGGGAGAATTTTTATACAAATCCAAAAAAAACGCTCAATTGGAAAAGGAATCTTCTATTTGGTTAGTGCCACCATACCATCCAGA
CACTGTTTAGTAATCTTTTGAAACTTACTAAAAGAGGTTTTTAATAATG
AGGTCCTTCTGTAGTGCCATGGTAGAAGAATTGAGGATGTCCCTGAAGTGC
CAGCGTCGGTTAAAACATAAGCCACAGGCCCCAGTTATTGTGAAAACAGAAGAAGTTATCAACATGCACACATTTAACGACAGAAGGTTGCCAGGTAAAG
AAACCATGGCATAAAGCTGGGAGGCCAAACACCCAAGCACAAACTGTCGTCTTTTTCCAAACAATTTAGCCAGAATGTTTCCTGTGGAAATATGCAACCT
GTGCAAAATAAAATGAGTTACCTCATGCCGCTGTGTCTATGAACTAGAGACTCTGTGATCTAAGCAGTTGCAATGATCAGACTTGATTTACAAGCATCAT
GGATCAACCAAGTTACACGGGGTTACACTGTTAATCATGGGTTCCTCCCTTCTTCTGAGTGAATGTTAACATGCGCATTTTGTGGCTGATTTCAAATGCA
GTCCAGTGAGAAATTACAGGTTCCTTTTGAAGCTCAACTGTTGCCAGGAGATGGAATATCAATGCCCAACAGGGCAACCAATAAAAGTGTCACTAAGAAT
ATAAATATT
  • refseq_GRIK2.F1 (forward primer)
  • refseq_GRIK2.R1 (reverse primer)
  • Single exon skipping

Frame 0

GCSLAQ*VKNMQRLLMGLGSGDSFLSL*PCRDR
VCGHHSTHPHFYPNPGAER*IGEVGAVRVGTETP
*RLFSRF*VIQSSGAPLNSCSVYCGLDILKEPH
MY*DLVVFLNMWNLAQWELRNLHSDLL*TQLTE
TEHCYPILPLPMIPRR*TFMIVLKHPRKPVISCL
LGWLPSSGLHTAHQQTQCSPSAMLWEFPTYRPA
GSTRCQTTKIPSMSVSTQTSLHSAVPF*TWCSF
SSGKPSRLCMMTALVSFVCKSSSKLHQGIIFDSK
FVSYLLIQRMQNPY*KK*KEARSFM*SLIVAMK
WQQAF*NRH*LWE**QNTIIISLPLWTSLLLML
SPTDTVVLT*QGSEY*IQKIPKSPPSLKSGRWND
CRHLRNPIQVCWMDL*RLMLL*CMMLCMWCLWP
FNSFPR*QSVPCSVIDINPGASGPAL*V*LKRH
IGKASQAE*LSTKPMA*EQILIWM*SV*RKKV*K
RLERGIQPVA*I*QKVKRESQRTSQIPYPIVL*
LLPPFWKSLMSFLRSLTNLSMVMIDLKAIALIS
SESYLQSLALHMKLDLWKMGNMEPRMMPMDNGME
WFVN*LIIKLTLQLLHWLLPMFERRSSTFPSPL
*HLE*VFCTASPMVQTQASSPS*ILSPLISGCI
FCWLTWVSVVCSLS*PGLVLMSGIIHTLATLTQT
WWKTILPC*IVSGLELELSCSKVLSSCPKHCPP
G*WEAFGGFSHLSSFLRILLT*PPF*QWNAWNP
LLTLLMI*LNKPR*NMEQ*RMVQP*LFSRNQKSP
RMTKCGPL*VAEGSQCWSKVMKKESSESSPLIM
LS*WSQQPSSLLPSGTVT*HRLAAL*TLKVMAL
ALPWVLHIETKLP*QFFSCKRKANCI**RRNGGG
AMVAQKRRAKRPVPWGFRILVASSLFWQPAWCF
QF
LWQWENFYTNPKKTLNWKRNLLFG*CHHTIQ
TLFSNLLKLTKRGF***
GPSVVPW*KN*GCP*SA
SVG*NISHRPQLL*KQKKLSTCTHLTTEGCQVK
KPWHKAGRPNTQAQTVVFFQTI*PECFLWKYAT
CAK*NELPHAAVSMN*RLCDLSSCNDQT*FTSIM
DQPSYTGLHC*SWVPPFF*VNVNMRILWLISNA
VQ*EITGSF*SSTVARRWNINAQQGNQ*KCH*E
YKY

Frame 1

VVPWRSE*RTCSDC*WVWEAETPSSLYDHAVIV
SAVTTRRILISTRTQEPNARSGKWVPCVWAQKH
HEDYFPDSK*SSLQAHR*TPALFTVDWIFSRNHT
CIKIWWYF*ICGIWPNGS*GTCIQICCEHN*QK
QNIATQYYPYL*YPEDKPL**F*SIQESL*SAV
SWGGCHLRAFTQLISKRSAVHLQCSGSSPHTDPL
EAPGVRQQRFLLCQSLPRLLFTQPCHFRPGAVF
QVENRHGCV**QHWSHSFARAHQSSIKV*SSTQ
NSSVTC*YKGCKTLTKRNEKRQGVSCNL*L*P*N
GSRHFKTGISYGNDDRILSLYLYHSGPLCS*C*
ALPIQWC*HDRVQNIKYRKYPSLLHH*KVVDGT
IAGTSETRFRFAGWIYDD*CCSNV*CCACGVCGR
STVSPDDSQFLAV*ST*TLALRDPLYESN*RGT
LGRPHRQNNFQQNQWLENRF*FGCDQSEGRRSR
KDWNVGSSQWPEYDRKSKGKASEHHRFLIQSFFD
CYHHFGRALCPF*EV*QTSLW**SI*RLLH*SP
QRVIYNPWLYI*N*TCGRWEIWSPG*CQWTMEW
NGS*TN*S*S*PCSCSTGYYLCSREGHRLFQALY
DTWNKYFVPQAQWYKPRRLLLPESSLP*YLDVY
SAGLLGCQLCALCHSQV*SL*VV*STPLQP*LR
RGGKQFYLAK*FLVWSWSSHAARF*AHAQSTVHQ
DSGRHLVVFHTYHHFFVYC*LSRLSDSGTHGIP
Y*LC**FS*TNQDRIWSSRGWCNHDFFQEIKNL
HV*QNVGLYE*QKAVSAGQK**RRNPASPHL*LC
FPNGVNNHRVCYPAEL*PDTDWRPYRL*RLWRW
HSHGFSISRQNYHSNSSAARGRQTAYDEGEMVE
GQWLPRRGEQRGQCPGGSEYWWHLHCSGSRLGAF
SF
CGSGRIFIQIQKKRSIGKGIFYLVSATIPSR
HCLVIF*NLLKEVFNN
EVLL*CHGRRIEDVPEV
PASVKT*ATGPSYCENRRSYQHAHI*RQKVAR*R
NHGIKLGGQTPKHKLSSFSKQFSQNVSCGNMQP
VQNKMSYLMPLCL*TRDSVI*AVAMIRLDLQAS
WINQVTRGYTVNHGFLPSSE*MLTCAFCG*FQMQ
SSEKLQVPFEAQLLPGDGISMPNRATNKSVTKN
INI

Frame 2

LFLGAVSEEHAAIANGFGKRRLLPLSMTMP*SC
LRSPLDASSFLPEPRSRTLDRGSGCRACGHRNT
MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTT
HVLRFGGIFEYVESGPMGAEELAFRFAVNTINRN
RTLLPNTTLTYDTQKINLYDSFEASKKACDQLS
LGVAAIFGPSHSSSANAVQSICNALGVPHIQTR
WKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFF
KWKTVTVVYDDSTGLIRLQELIKAPSRYNLRLK
IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHE
MAAGILKQALAMGMMTEYYHYIFTTLDLFALDVE
PYRYSGVNMTGFRILNTENTQVSSIIEKWSMER
LQAPPKPDSGLLDGFMTTDAALMYDAVHVVSVA
VQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAH
WEGLTGRITFNKTNGLRTDFDLDVISLKEEGLE
KIGTWDPASGLNMTESQKGKPANITDSLSNRSL
IVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLL
RELSTILGFTYEIRLVEDGKYGAQDDANGQWNG
MVRELIDHKADLAVAPLAITYVREKVIDFSKPF
MTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYI
LLAYLGVSCVLFVIARFSPYEWYNPHPCNPDSD
VVENNFTLLNSFWFGVGALMQQGSELMPKALST
RIVGGIWWFFTLIIISSYTANLAAFLTVERMESP
IDSADDLAKQTKIEYGAVEDGATMTFFKKSKIS
TYDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDY
AFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVG
TPMGSPYRDKITIAILQLQEEGKLHMMKEKWWR
GNGCPEEESKEASALGVQNIGGIFIVLAAGLVL
SV
FVAVGEFLYKSKKNAQLEKESSIWLVPPYHPD
TV**SFETY*KRFLIM
RSFCSAMVEELRMSLKC
QRRLKHKPQAPVIVKTEEVINMHTFNDRRLPGK
ETMA*SWEAKHPSTNCRLFPNNLARMFPVEICNL
CKIK*VTSCRCVYELETL*SKQLQ*SDLIYKHH
GSTKLHGVTLLIMGSSLLLSEC*HAHFVADFKC
SPVRNYRFLLKLNCCQEMEYQCPTGQPIKVSLRI
*I

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