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Sequences

Sequence NM_203506

AGTTCTCGCGGGACACCGACGGGGAGCGGAAGCCAGGAGGTATTGCTGCTTCGGCGACCGGGCGGCGGCAGCGGCGGCGGCGGCTGTGGCAGAGTCTGTG CCTGTGGCGGTGACGGCGGCGGGAGCAAGCGCTGCCCTCGCAGAGCAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGTGGAGGGGCGGGCCGGACGCTG AGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCA GCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACG ACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGTTTTGAACGAAGAATGTGATCAGAACTGGTACAAGGCAGAGCTTAATGGAAAAGACGGCTTCAT TCCCAAGAACTACATAGAAATGAAACCACATCCGTTTGGAAACGATGTGCAGCACTTCAAGGTGCTCCGAGATGGAGCCGGGAAGTACTTCCTCTGGGTG GTGAAGTTCAATTCTTTGAATGAGCTGGTGGATTATCACAGATCTACATCTGTCTCCAGAAACCAGCAGATATTCCTGCGGGACATAGAACAGGTGCCAC AGCAGCCGACATACGTCCAGGCCCTCTTTGACTTTGATCCCCAGGAGGATGGAGAGCTGGGCTTCCGCCGGGGAGATTTTATCCATGTCATGGATAACTC AGACCCCAACTGGTGGAAAGGAGCTTGCCACGGGCAGACCGGCATGTTTCCCCGCAATTATGTCACCCCCGTGAACCGGAACGTCTAAGAGTCAAGAAGC AATTATTTAAAGAAAGTGAAAAATGTAAAACACATACAAAAGAATTAAACCCACAAGCTGCCTCTGACAGCAGCCTGTGAGGGAGTGCAGAACACCTGGC CGGGTCACCCTGTGACCCTCTCACTTTGGTTGGAACTTTAGGGGGTGGGAGGGGGCGTTGGATTTAAAAATGCCAAAACTTACCTATAAATTAAGAAGAG TTTTTATTACAAATTTTCACTGCTGCTCCTCTTTCCCCTCCTTTGTCTTTTTTTTCATCCTTTTTTCTCTTCTGTCCATCAGTGCATGACGTTTAAGGCC ACGTATAGTCCTAGCTGACGCCAATAATAAAAAACAAGAAACCAAGTGGGCTGGTATTCTCTCTATGCAAAATGTCTGTTTTAGTTGGAATGACTGAAAG AAGAACAGCTGTTCCTGTGTTCTTCGTATATACACACAAAAAGGAGCGGGCAGGGCCGCTCGATGCCTTTGCTGTTTAGCTTCCTCCAGAGGAGGGGACT TGTAGGAATCTGCCTTCCAGCCCAGACCCCCAGTGTATTTTGTCCAAGTTCACAGTAGAGTAGGGTAGAAGGAAAGCATGTCTCTGCTTCCATGGCTTCC TGAGAAAGCCCACCTGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACAAGGTCAGGAGTTCGAGACC AACCTAGCCAACATGGTGAAACCCCGTCTCTACTAAAAATAAGAAATTAGCCGGGTGTGGCACGCACCTGTAGTCCCAGCTACTTGGGAGCCTGAGGCAG GAGAATCGCTTGAACCTGGGAAGTGGAGGTTGAGTGAGCCGGGACCGTGCCATTGTACTCCAGCCTGGGTGACAGAGCGAGATTCCGTCTCAAAAAAAAA AAAAAAAAGCCCACCTGAAAGCCTGTCTCTTTCCACTTTGTTGGCCCTTCCAGTGGGATTATCGAGCATGTTGTTTTTTCATAGTGCCTTTTTCCTTATT TCAAGGGTTGCTTCTGAGTGGTGTTTTTTTTTTTTTTTTAATTTGTTTTGTTTTAAAATAAGTTAAAGGCAGTCCAGAGCTTTTCAGCCAATTTGTCTCC TACTCTGTGTAAATATTTTTCCCTCCGGGCAGGGGAGCCAGGGTAGAGCAAAGGAGACAAAGCAGGAGTGGAAGGTGAGGCGTTCTCCTGCTTGTACTAA GCCAGGAGGCTTTAAGCTCCAGCTTTAAGGGTTGTGAGCCCCTTGGGGGTTCAGGGAACTGCTTGCCCAGGGTGCAGTGTGAGTGTGATGGGCCACCGGG GCAAGAGGGAAGGTGACCGCCCAGCTCTCCCACATCCCACTGGATCTGGCTTACAGGGGGGTCGGAAGCCTGTCCTCACCGTCTCGGGGGTTGTGGCCCC CGCCCCCTCCCTATATGCACCCCTGGAACCAGCAAGTCCCAGACAAGGAGAGCGGAGGAGGAAGTCATGGGAACGCAGCCTCCAGTTGTAGCAGGTTTCA CTATTCCTATGCTGGGGTACACAGTGAGAGTACTCACTTTTCACTTGTCTTGCTCTTAGATTGGGCCATGGCTTTCATCCTGTGTCCCCTGACCTGTCCA GGTGAGTGTGAGGGCAGCACTGGGAAGCTGGAGTGCTGCTTGTGCCTCCCTTCCCAGTGGGCTGTGTTGACTGCTGCTCCCCACCCCTACCGATGGTCCC AGGAAGCAGGGAGAGTTGGGGAAGGCAAGATTGGAAAGACAGGAAGACCAAGGCCTCGGCAGAACTCTCTGTCTTCTCTCCACTTCTGGTCCCCTGTGGT GATGTGCCTGTAATCTTTTTCTCCACCCAAACCCCTTCCCACGACAAAAACAAGACTGCCTCCCTCTCTTCCGGGAGCTGGTGACAGCCTTGGGCCTTTC AGTCCCAAAGCGGCCGATGGGAGTCTCCCTCCGACTCCAGATATGAACAGGGCCCAGGCCTGGAGCGTTTGCTGTGCCAGGAGGCGGCAGCTCTTCTGGG CAGAGCCTGTCCCCGCCTTCCCTCACTCTTCCTCATCCTGCTTCTCTTTTCCTCGCAGATGATAAAAGGAATCTGGCATTCTACACCTGGACCATTTGAT TGTTTTATTTTGGAATTGGTGTATATCATGAAGCCTTGCTGAACTAAGTTTTGTGTGTATATATTTAAAAAAAAAATCAGTGTTTAAATAAAGACCTATG TACTTAATCCTTTAACTCTGCGGATAGCATTTGGTAGGTAGTGATTAACTGTGAATAATAAATACACAATGAATTCTTCA

refseq_GRB2.F2 (forward primer)
refseq_GRB2.R2 (reverse primer)
Single exon skipping

Frame 0

SSRGTPTGSGSQEVLLLRRPGGGSGGGGCGRVC ACGGDGGGSKRCPRRAALGSPAARSVVEGRAGR* AEQLRHGWHCVSQSAGASPRREARLSPERWVAS AGKTPFPLLQAAEH*AALRMEAIAKYDFKATAD DELSFKRGDILKVLNEECDQNWYKAELNGKDGFI PKNYIEMKPHPFGNDVQHFKVLRDGAGKYFLWV VKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVP QQPTYVQALFDFDPQEDGELGFRRGDFIHVMDNS DPNWWKGACHGQTGMFPRNYVTPVNRNV*ESRS NYLKKVKNVKHIQKN*THKLPLTAACEGVQNTW PGHPVTLSLWLEL*GVGGGVGFKNAKTYL*IKKS FYYKFSLLLLFPLLCLFFHPFFSSVHQCMTFKA TYSPS*RQ**KTRNQVGWYSLYAKCLF*LE*LK EEQLFLCSSYIHTKRSGQGRSMPLLFSFLQRRGL VGICLPAQTPSVFCPSSQ*SRVEGKHVSASMAS *ESPPGLGAVAHACNPSTLGGQGGRITRSGVRD QPSQHGETPSLLKIRN*PGVARTCSPSYLGA*GR RIA*TWEVEVE*AGTVPLYSSLGDRARFRLKKK KKKPT*KPVSFHFVGPSSGIIEHVVFS*CLFPY FKGCF*VVFFFFF*FVLF*NKLKAVQSFSANLSP TLCKYFSLRAGEPG*SKGDKAGVEGEAFSCLY* ARRL*APALRVVSPLGVQGTACPGCSVSVMGHR GKREGDRPALPHPTGSGLQGGRKPVLTVSGVVAP APSLYAPLEPASPRQGERRRKSWERSLQL*QVS LFLCWGTQ*EYSLFTCLALRLGHGFHPVSPDLS R*V*GQHWEAGVLLVPPFPVGCVDCCSPPLPMVP GSRESWGRQDWKDRKTKASAELSVFSPLLVPCG DVPVIFFSTQTPSHDKNKTASLSSGSW*QPWAF QSQSGRWESPSDSRYEQGPGLERLLCQEAAALLG RACPRLPSLFLILLLFSSQMIKGIWHSTPGPFD CFILELVYIMKPC*TKFCVYIFKKKISV*IKTY VLNPLTLRIAFGR**LTVNNKYTMNSS

Frame 1

VLAGHRRGAEARRYCCFGDRAAAAAAAAVAESV PVAVTAAGASAALAEQPWGRRPLAALWRGGPDA ERSSCATGGIVCPRVPERVPEERRG*AQSAGLLQ QGRLPSPCFRLLSTEQRSEWKPSPNMTSKLLQT TS*ASKGGTSSRF*TKNVIRTGTRQSLMEKTAS FPRTT*K*NHIRLETMCSTSRCSEMEPGSTSSGW *SSIL*MSWWIITDLHLSPETSRYSCGT*NRCH SSRHTSRPSLTLIPRRMESWASAGEILSMSWIT QTPTGGKELATGRPACFPAIMSPP*TGTSKSQEA II*RK*KM*NTYKRIKPTSCL*QQPVRECRTPG RVTL*PSHFGWNFRGWEGALDLKMPKLTYKLRR VFITNFHCCSSFPSFVFFFILFSLLSISA*RLRP RIVLADANNKKQETKWAGILSMQNVCFSWND*K KNSCSCVLRIYTQKGAGRAARCLCCLASSRGGD L*ESAFQPRPPVYFVQVHSRVG*KESMSLLPWLP EKAHLGWARWLTPVIPALWEAKVGGSQGQEFET NLANMVKPRLY*K*EISRVWHAPVVPATWEPEA GESLEPGKWRLSEPGPCHCTPAWVTERDSVSKKK KKSPPESLSLSTLLALPVGLSSMLFFHSAFFLI SRVASEWCFFFFFNLFCFKIS*RQSRAFQPICL LLCVNIFPSGQGSQGRAKETKQEWKVRRSPACTK PGGFKLQL*GL*APWGFRELLAQGAV*V*WATG ARGKVTAQLSHIPLDLAYRGVGSLSSPSRGLWP PPPPYMHPWNQQVPDKESGGGSHGNAASSCSRFH YSYAGVHSESTHFSLVLLLDWAMAFILCPLTCP GECEGSTGKLECCLCLPSQWAVLTAAPHPYRWS QEAGRVGEGKIGKTGRPRPRQNSLSSLHFWSPVV MCL*SFSPPKPLPTTKTRLPPSLPGAGDSLGPF SPKAADGSLPPTPDMNRAQAWSVCCARRRQLFW AEPVPAFPHSSSSCFSFPRR**KESGILHLDHLI VLFWNWCIS*SLAELSFVCIYLKKKSVFK*RPM YLIL*LCG*HLVGSD*L*IINTQ*IL

Frame 2

FSRDTDGERKPGGIAASATGRRQRRRRLWQSLC LWR*RRREQALPSQSSLGVAGRSQRCGGAGRTL SGAAAPRVALCVPECRSESQKRGEAKPRALGCF SREDSLPPASGC*ALSSAQNGSHRQI*LQSYCRR RAELQKGGHPQGFERRM*SELVQGRA*WKRRLH SQELHRNETTSVWKRCAALQGAPRWSREVLPLG GEVQFFE*AGGLSQIYICLQKPADIPAGHRTGAT AADIRPGPL*L*SPGGWRAGLPPGRFYPCHG*L RPQLVERSLPRADRHVSPQLCHPREPERLRVKK QLFKESEKCKTHTKELNPQAASDSSL*GSAEHLA GSPCDPLTLVGTLGGGRGRWI*KCQNLPIN*EE FLLQIFTAAPLSPPLSFFSSFFLFCPSVHDV*G HV*S*LTPIIKNKKPSGLVFSLCKMSVLVGMTER RTAVPVFFVYTHKKERAGPLDAFAV*LPPEEGT CRNLPSSPDPQCILSKFTVE*GRRKACLCFHGF LRKPTWAGRGGSRL*SQHFGRPRWADHKVRSSRP T*PTW*NPVSTKNKKLAGCGTHL*SQLLGSLRQ ENRLNLGSGG*VSRDRAIVLQPG*QSEIPSQKK KKKAHLKACLFPLCWPFQWDYRACCFFIVPFSLF QGLLLSGVFFFFLICFVLK*VKGSPELFSQFVS YSV*IFFPPGRGARVEQRRQSRSGR*GVLLLVL SQEALSSSFKGCEPLGGSGNCLPRVQCECDGPPG QEGR*PPSSPTSHWIWLTGGSEACPHRLGGCGP RPLPICTPGTSKSQTRRAEEEVMGTQPPVVAGF TIPMLGYTVRVLTFHLSCS*IGPWLSSCVP*PVQ VSVRAALGSWSAACASLPSGLC*LLLPTPTDGP RKQGELGKARLERQEDQGLGRTLCLLSTSGPLW *CACNLFLHPNPFPRQKQDCLPLFRELVTALGLS VPKRPMGVSLRLQI*TGPRPGAFAVPGGGSSSG QSLSPPSLTLPHPASLFLADDKRNLAFYTWTI* LFYFGIGVYHEALLN*VLCVYI*KKNQCLNKDLC T*SFNSADSIW*VVINCE**IHNEFF

Sequence NM_002086

AGTTCTCGCGGGACACCGACGGGGAGCGGAAGCCAGGAGGTATTGCTGCTTCGGCGACCGGGCGGCGGCAGCGGCGGCGGCGGCTGTGGCAGAGTCTGTG CCTGTGGCGGTGACGGCGGCGGGAGCAAGCGCTGCCCTCGCAGAGCAGCCTTGGGGTCGCCGGCCGCTCGCAGCGTTGTGGAGGGGCGGGCCGGACGCTG AGCGGAGCAGCTGCGCCACGGGTGGCATTGTGTGTCCCAGAGTGCCGGAGCGAGTCCCAGAAGAGAGGCGAGGCTAAGCCCAGAGCGCTGGGTTGCTTCA GCAGGGAAGACTCCCTTCCCCCTGCTTCAGGCTGCTGAGCACTGAGCAGCGCTCAGAATGGAAGCCATCGCCAAATATGACTTCAAAGCTACTGCAGACG ACGAGCTGAGCTTCAAAAGGGGGGACATCCTCAAGGTTTTGAACGAAGAATGTGATCAGAACTGGTACAAGGCAGAGCTTAATGGAAAAGACGGCTTCAT TCCCAAGAACTACATAGAAATGAAACCACATCCGTGGTTTTTTGGCAAAATCCCCAGAGCCAAGGCAGAAGAAATGCTTAGCAAACAGCGGCACGATGGG GCCTTTCTTATCCGAGAGAGTGAGAGCGCTCCTGGGGACTTCTCCCTCTCTGTCAAGTTTGGAAACGATGTGCAGCACTTCAAGGTGCTCCGAGATGGAG CCGGGAAGTACTTCCTCTGGGTGGTGAAGTTCAATTCTTTGAATGAGCTGGTGGATTATCACAGATCTACATCTGTCTCCAGAAACCAGCAGATATTCCT GCGGGACATAGAACAGGTGCCACAGCAGCCGACATACGTCCAGGCCCTCTTTGACTTTGATCCCCAGGAGGATGGAGAGCTGGGCTTCCGCCGGGGAGAT TTTATCCATGTCATGGATAACTCAGACCCCAACTGGTGGAAAGGAGCTTGCCACGGGCAGACCGGCATGTTTCCCCGCAATTATGTCACCCCCGTGAACC GGAACGTCTAAGAGTCAAGAAGCAATTATTTAAAGAAAGTGAAAAATGTAAAACACATACAAAAGAATTAAACCCACAAGCTGCCTCTGACAGCAGCCTG TGAGGGAGTGCAGAACACCTGGCCGGGTCACCCTGTGACCCTCTCACTTTGGTTGGAACTTTAGGGGGTGGGAGGGGGCGTTGGATTTAAAAATGCCAAA ACTTACCTATAAATTAAGAAGAGTTTTTATTACAAATTTTCACTGCTGCTCCTCTTTCCCCTCCTTTGTCTTTTTTTTCATCCTTTTTTCTCTTCTGTCC ATCAGTGCATGACGTTTAAGGCCACGTATAGTCCTAGCTGACGCCAATAATAAAAAACAAGAAACCAAGTGGGCTGGTATTCTCTCTATGCAAAATGTCT GTTTTAGTTGGAATGACTGAAAGAAGAACAGCTGTTCCTGTGTTCTTCGTATATACACACAAAAAGGAGCGGGCAGGGCCGCTCGATGCCTTTGCTGTTT AGCTTCCTCCAGAGGAGGGGACTTGTAGGAATCTGCCTTCCAGCCCAGACCCCCAGTGTATTTTGTCCAAGTTCACAGTAGAGTAGGGTAGAAGGAAAGC ATGTCTCTGCTTCCATGGCTTCCTGAGAAAGCCCACCTGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGGAT CACAAGGTCAGGAGTTCGAGACCAACCTAGCCAACATGGTGAAACCCCGTCTCTACTAAAAATAAGAAATTAGCCGGGTGTGGCACGCACCTGTAGTCCC AGCTACTTGGGAGCCTGAGGCAGGAGAATCGCTTGAACCTGGGAAGTGGAGGTTGAGTGAGCCGGGACCGTGCCATTGTACTCCAGCCTGGGTGACAGAG CGAGATTCCGTCTCAAAAAAAAAAAAAAAAAGCCCACCTGAAAGCCTGTCTCTTTCCACTTTGTTGGCCCTTCCAGTGGGATTATCGAGCATGTTGTTTT TTCATAGTGCCTTTTTCCTTATTTCAAGGGTTGCTTCTGAGTGGTGTTTTTTTTTTTTTTTTAATTTGTTTTGTTTTAAAATAAGTTAAAGGCAGTCCAG AGCTTTTCAGCCAATTTGTCTCCTACTCTGTGTAAATATTTTTCCCTCCGGGCAGGGGAGCCAGGGTAGAGCAAAGGAGACAAAGCAGGAGTGGAAGGTG AGGCGTTCTCCTGCTTGTACTAAGCCAGGAGGCTTTAAGCTCCAGCTTTAAGGGTTGTGAGCCCCTTGGGGGTTCAGGGAACTGCTTGCCCAGGGTGCAG TGTGAGTGTGATGGGCCACCGGGGCAAGAGGGAAGGTGACCGCCCAGCTCTCCCACATCCCACTGGATCTGGCTTACAGGGGGGTCGGAAGCCTGTCCTC ACCGTCTCGGGGGTTGTGGCCCCCGCCCCCTCCCTATATGCACCCCTGGAACCAGCAAGTCCCAGACAAGGAGAGCGGAGGAGGAAGTCATGGGAACGCA GCCTCCAGTTGTAGCAGGTTTCACTATTCCTATGCTGGGGTACACAGTGAGAGTACTCACTTTTCACTTGTCTTGCTCTTAGATTGGGCCATGGCTTTCA TCCTGTGTCCCCTGACCTGTCCAGGTGAGTGTGAGGGCAGCACTGGGAAGCTGGAGTGCTGCTTGTGCCTCCCTTCCCAGTGGGCTGTGTTGACTGCTGC TCCCCACCCCTACCGATGGTCCCAGGAAGCAGGGAGAGTTGGGGAAGGCAAGATTGGAAAGACAGGAAGACCAAGGCCTCGGCAGAACTCTCTGTCTTCT CTCCACTTCTGGTCCCCTGTGGTGATGTGCCTGTAATCTTTTTCTCCACCCAAACCCCTTCCCACGACAAAAACAAGACTGCCTCCCTCTCTTCCGGGAG CTGGTGACAGCCTTGGGCCTTTCAGTCCCAAAGCGGCCGATGGGAGTCTCCCTCCGACTCCAGATATGAACAGGGCCCAGGCCTGGAGCGTTTGCTGTGC CAGGAGGCGGCAGCTCTTCTGGGCAGAGCCTGTCCCCGCCTTCCCTCACTCTTCCTCATCCTGCTTCTCTTTTCCTCGCAGATGATAAAAGGAATCTGGC ATTCTACACCTGGACCATTTGATTGTTTTATTTTGGAATTGGTGTATATCATGAAGCCTTGCTGAACTAAGTTTTGTGTGTATATATTTAAAAAAAAAAT CAGTGTTTAAATAAAGACCTATGTACTTAATCCTTTAACTCTGCGGATAGCATTTGGTAGGTAGTGATTAACTGTGAATAATAAATACACAATGAATTCT TCA

refseq_GRB2.F2 (forward primer)
refseq_GRB2.R2 (reverse primer)
Single exon skipping

Frame 0

SSRGTPTGSGSQEVLLLRRPGGGSGGGGCGRVC ACGGDGGGSKRCPRRAALGSPAARSVVEGRAGR* AEQLRHGWHCVSQSAGASPRREARLSPERWVAS AGKTPFPLLQAAEH*AALRMEAIAKYDFKATAD DELSFKRGDILKVLNEECDQNWYKAELNGKDGFI PKNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDG AFLIRESESAPGDFSLSVKFGNDVQHFKVLRDG AGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFL RDIEQVPQQPTYVQALFDFDPQEDGELGFRRGD FIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVN RNV*ESRSNYLKKVKNVKHIQKN*THKLPLTAAC EGVQNTWPGHPVTLSLWLEL*GVGGGVGFKNAK TYL*IKKSFYYKFSLLLLFPLLCLFFHPFFSSV HQCMTFKATYSPS*RQ**KTRNQVGWYSLYAKCL F*LE*LKEEQLFLCSSYIHTKRSGQGRSMPLLF SFLQRRGLVGICLPAQTPSVFCPSSQ*SRVEGK HVSASMAS*ESPPGLGAVAHACNPSTLGGQGGRI TRSGVRDQPSQHGETPSLLKIRN*PGVARTCSP SYLGA*GRRIA*TWEVEVE*AGTVPLYSSLGDR ARFRLKKKKKKPT*KPVSFHFVGPSSGIIEHVVF S*CLFPYFKGCF*VVFFFFF*FVLF*NKLKAVQ SFSANLSPTLCKYFSLRAGEPG*SKGDKAGVEG EAFSCLY*ARRL*APALRVVSPLGVQGTACPGCS VSVMGHRGKREGDRPALPHPTGSGLQGGRKPVL TVSGVVAPAPSLYAPLEPASPRQGERRRKSWER SLQL*QVSLFLCWGTQ*EYSLFTCLALRLGHGFH PVSPDLSR*V*GQHWEAGVLLVPPFPVGCVDCC SPPLPMVPGSRESWGRQDWKDRKTKASAELSVF SPLLVPCGDVPVIFFSTQTPSHDKNKTASLSSGS W*QPWAFQSQSGRWESPSDSRYEQGPGLERLLC QEAAALLGRACPRLPSLFLILLLFSSQMIKGIW HSTPGPFDCFILELVYIMKPC*TKFCVYIFKKKI SV*IKTYVLNPLTLRIAFGR**LTVNNKYTMNS S

Frame 1

VLAGHRRGAEARRYCCFGDRAAAAAAAAVAESV PVAVTAAGASAALAEQPWGRRPLAALWRGGPDA ERSSCATGGIVCPRVPERVPEERRG*AQSAGLLQ QGRLPSPCFRLLSTEQRSEWKPSPNMTSKLLQT TS*ASKGGTSSRF*TKNVIRTGTRQSLMEKTAS FPRTT*K*NHIRGFLAKSPEPRQKKCLANSGTMG PFLSERVRALLGTSPSLSSLETMCSTSRCSEME PGSTSSGW*SSIL*MSWWIITDLHLSPETSRYS CGT*NRCHSSRHTSRPSLTLIPRRMESWASAGEI LSMSWITQTPTGGKELATGRPACFPAIMSPP*T GTSKSQEAII*RK*KM*NTYKRIKPTSCL*QQP VRECRTPGRVTL*PSHFGWNFRGWEGALDLKMPK LTYKLRRVFITNFHCCSSFPSFVFFFILFSLLS ISA*RLRPRIVLADANNKKQETKWAGILSMQNV CFSWND*KKNSCSCVLRIYTQKGAGRAARCLCCL ASSRGGDL*ESAFQPRPPVYFVQVHSRVG*KES MSLLPWLPEKAHLGWARWLTPVIPALWEAKVGG SQGQEFETNLANMVKPRLY*K*EISRVWHAPVVP ATWEPEAGESLEPGKWRLSEPGPCHCTPAWVTE RDSVSKKKKKSPPESLSLSTLLALPVGLSSMLF FHSAFFLISRVASEWCFFFFFNLFCFKIS*RQSR AFQPICLLLCVNIFPSGQGSQGRAKETKQEWKV RRSPACTKPGGFKLQL*GL*APWGFRELLAQGA V*V*WATGARGKVTAQLSHIPLDLAYRGVGSLSS PSRGLWPPPPPYMHPWNQQVPDKESGGGSHGNA ASSCSRFHYSYAGVHSESTHFSLVLLLDWAMAF ILCPLTCPGECEGSTGKLECCLCLPSQWAVLTAA PHPYRWSQEAGRVGEGKIGKTGRPRPRQNSLSS LHFWSPVVMCL*SFSPPKPLPTTKTRLPPSLPG AGDSLGPFSPKAADGSLPPTPDMNRAQAWSVCCA RRRQLFWAEPVPAFPHSSSSCFSFPRR**KESG ILHLDHLIVLFWNWCIS*SLAELSFVCIYLKKK SVFK*RPMYLIL*LCG*HLVGSD*L*IINTQ*IL

Frame 2

FSRDTDGERKPGGIAASATGRRQRRRRLWQSLC LWR*RRREQALPSQSSLGVAGRSQRCGGAGRTL SGAAAPRVALCVPECRSESQKRGEAKPRALGCF SREDSLPPASGC*ALSSAQNGSHRQI*LQSYCRR RAELQKGGHPQGFERRM*SELVQGRA*WKRRLH SQELHRNETTSVVFWQNPQSQGRRNA*QTAARW GLSYPRE*ERSWGLLPLCQVWKRCAALQGAPRWS REVLPLGGEVQFFE*AGGLSQIYICLQKPADIP AGHRTGATAADIRPGPL*L*SPGGWRAGLPPGR FYPCHG*LRPQLVERSLPRADRHVSPQLCHPREP ERLRVKKQLFKESEKCKTHTKELNPQAASDSSL *GSAEHLAGSPCDPLTLVGTLGGGRGRWI*KCQ NLPIN*EEFLLQIFTAAPLSPPLSFFSSFFLFCP SVHDV*GHV*S*LTPIIKNKKPSGLVFSLCKMS VLVGMTERRTAVPVFFVYTHKKERAGPLDAFAV *LPPEEGTCRNLPSSPDPQCILSKFTVE*GRRKA CLCFHGFLRKPTWAGRGGSRL*SQHFGRPRWAD HKVRSSRPT*PTW*NPVSTKNKKLAGCGTHL*S QLLGSLRQENRLNLGSGG*VSRDRAIVLQPG*QS EIPSQKKKKKAHLKACLFPLCWPFQWDYRACCF FIVPFSLFQGLLLSGVFFFFLICFVLK*VKGSP ELFSQFVSYSV*IFFPPGRGARVEQRRQSRSGR* GVLLLVLSQEALSSSFKGCEPLGGSGNCLPRVQ CECDGPPGQEGR*PPSSPTSHWIWLTGGSEACP HRLGGCGPRPLPICTPGTSKSQTRRAEEEVMGTQ PPVVAGFTIPMLGYTVRVLTFHLSCS*IGPWLS SCVP*PVQVSVRAALGSWSAACASLPSGLC*LL LPTPTDGPRKQGELGKARLERQEDQGLGRTLCLL STSGPLW*CACNLFLHPNPFPRQKQDCLPLFRE LVTALGLSVPKRPMGVSLRLQI*TGPRPGAFAV PGGGSSSGQSLSPPSLTLPHPASLFLADDKRNLA FYTWTI*LFYFGIGVYHEALLN*VLCVYI*KKN QCLNKDLCT*SFNSADSIW*VVINCE**IHNEF F