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Sequences

Sequence NM_198569

CCAAGTACCTAGGGTGGTGGCCGAGTCCCGCCTCCCGCCAGCGGGGGCGAGGACCTGCGACGCGCACCCCTGCCTGGCCCGGTCTCCTCAGCACCAGCCC CACGCACACCCTACTTCCTCAGCTTCTCGCCCTCACCCTGCCAACTTCCCTGCGAGGAGGGACCTGCCGCCAGCCTGCTTCCTCGTCCGCAGGCCCTGCG CTGAACGCTGCCGCGCCCAGGGTTCACCTTGCGCCGTCGGGAAAGCCCATGAACTCTCCAGAAACGGCGTAAAGGAGGGTCCCGCCGCGGCGCAGGGCTG GGGCGCCTGGGTTCCCCCTGGGTGGAGCAGCGGCAGCAGAGCGGGAAAGTGGTGGAGGATGATCTTGCGGCCAAAGGGGACCTCGGCGCAGTAATGTCAA CATGATGTTTCGCTCAGATCGAATGTGGAGCTGCCATTGGAAATGGAAGCCCAGTCCTCTCCTGTTCTTATTTGCTTTATATATCATGTGTGTTCCTCAC TCAGTGTGGGGATGTGCCAACTGCCGAGTGGTTTTGTCCAACCCTTCTGGGACCTTTACTTCTCCATGCTACCCTAACGACTACCCAAACAGCCAGGCTT GCATGTGGACGCTCCGAGCCCCCACCGGTTATATCATTCAGATAACATTTAACGACTTTGACATTGAAGAAGCTCCCAATTGCATTTATGACTCATTATC CCTTGATAATGGAGAGAGCCAGACTAAATTTTGTGGAGCAACTGCCAAAGGCCTATCATTTAACTCAAGTGCGAATGAGATGCATGTGTCCTTTTCAAGT GACTTTAGCATCCAGAAGAAAGGTTTCAATGCCAGCTACATCAGAGTTGCCGTGTCCTTAAGGAATCAAAAGGTCATTTTACCCCAGACATCAGATGCTT ACCAGGTATCTGTTGCAAAAAGCATCTCTATTCCAGAGCTCAGTGCTTTCACACTCTGCTTTGAAGCAACCAAAGTTGGCCATGAAGACAGTGATTGGAC AGCTTTCTCCTACTCAAATGCATCCTTCACACAATTGCTCAGTTTTGGAAAGGCCAAGAGTGGCTACTTTCTATCCATTTCTGATTCAAAATGTTTGTTG AATAATGCATTACCTGTCAAAGAAAAAGAAGACATTTTTGCAGAAAGCTTTGAACAGCTCTGCCTTGTTTGGAATAATTCTTTGGGCTCTATTGGTGTAA ATTTCAAAAGAAACTATGAAACAGTTCCATGTGATTCTACCATTAGTAAAGTTATTCCTGGGAATGGGAAATTGTTGTTGGGCTCCAATCAAAATGAAAT TGTCTCTCTAAAAGGGGACATTTATAACTTTCGACTTTGGAATTTTACCATGAATGCCAAAATCCTCTCCAACCTCAGCTGTAATGTGAAAGGGAATGTA GTCGACTGGCAAAATGACTTCTGGAATATCCCAAACCTAGCTCTGAAAGCTGAAAGCAACCTAAGCTGTGGTTCCTACCTGATCCCGCTCCCAGCAGCAG AACTGGCCAGCTGTGCAGACCTGGGGACCCTCTGTCAAGCTACTGTAAACTCTCCTAGTACTACACCACCCACTGTCACCACTAACATGCCTGTTACTAA CAGAATCGATAAACAAAGGAATGATGGAATTATCTATAGAATATCCGTAGTGATTCAGAACATCCTTCGTCACCCTGAGGTAAAAGTACAGAGCAAGGTG GCAGAATGGCTCAATTCAACCTTCCAAAATTGGAACTACACGGTTTATGTCGTTAATATCAGTTTTCACCTGAGTGCTGGAGAGGACAAGATTAAAGTCA AGAGAAGCCTTGAGGATGAGCCAAGGTTGGTGCTTTGGGCCCTTCTAGTTTACAATGCTACCAACAATACTAATTTGGAAGGAAAAATCATTCAGCAGAA GCTCCTAAAAAATAATGAGTCCTTGGATGAAGGCTTGAGGCTACATACAGTGAATGTGAGACAACTGGGTCATTGTCTTGCCATGGAGGAACCCAAAGGC TACTACTGGCCATCTATCCAACCTTCTGAATACGTTCTTCCTTGTCCAGACAAGCCTGGCTTTTCTGCTTCTCGGATATGTTTTTACAATGCTACCAACC CATTGGTAACCTACTGGGGACCTGTTGATATCTCCAACTGTTTAAAAGAAGCAAATGAAGTTGCTAACCAGATTTTAAATTTAACTGCTGATGGGCAGAA CTTAACCTCAGCCAATATTACCAACATTGTGGAACAGGTCAAAAGAATTGTGAATAAAGAAGAAAACATTGATATAACACTTGGCTCAACTCTAATGAAT ATATTTTCTAATATCTTAAGCAGTTCAGACAGTGACTTGCTTGAGTCATCTTCTGAAGCTTTAAAAACAATTGATGAATTGGCCTTCAAGATAGACCTAA ATAGCACATCACATGTGAATATTACAACTCGGAACTTGGCTCTCAGCGTATCATCCCTGTTACCAGGGACAAATGCAATTTCAAATTTTAGCATTGGTCT TCCAAGCAATAATGAATCGTATTTCCAGATGGATTTTGAGAGTGGACAAGTGGATCCACTGGCATCTGTAATTTTGCCTCCAAACTTACTTGAGAATTTA AGTCCAGAAGATTCTGTATTAGTTAGAAGAGCACAGTTTACTTTCTTCAACAAAACTGGACTTTTCCAGGATGTAGGACCCCAAAGAAAAACTTTAGTGA GTTATGTGATGGCGTGCAGTATTGGAAACATTACTATCCAGAATCTGAAGGATCCTGTTCAAATAAAAATCAAACATACAAGAACTCAGGAAGTGCATCA TCCCATCTGTGCCTTCTGGGATCTGAACAAAAACAAAAGTTTTGGAGGATGGAACACGTCAGGATGTGTTGCACACAGAGATTCAGATGCAAGTGAGACA GTCTGCCTGTGTAACCACTTCACACACTTTGGAGTTCTGATGGACCTTCCAAGAAGTGCCTCACAGTTAGATGCAAGAAACACTAAAGTCCTCACTTTCA TCAGCTATATTGGGTGTGGAATATCTGCTATTTTTTCAGCAGCAACTCTCCTGACATATGTTGCTTTTGAGAAATTGCGAAGGGATTATCCCTCCAAAAT CTTGATGAACCTGAGCACAGCCCTGCTGTTCCTGAATCTCCTCTTCCTCCTAGATGGCTGGATCACCTCCTTCAATGTGGATGGACTTTGCATTGCTGTT GCAGTCCTGTTGCATTTCTTCCTTCTGGCAACCTTTACCTGGATGGGGCTAGAAGCAATTCACATGTACATTGCTCTAGTTAAAGTATTTAACACTTACA TTCGCCGATACATTCTAAAATTCTGCATCATTGGCTGGGGTTTGCCTGCCTTAGTGGTGTCAGTTGTTCTAGCGAGCAGAAACAACAATGAAGTCTATGG AAAAGAAAGTTATGGGAAAGAAAAAGGTGATGAATTCTGTTGGATTCAAGATCCAGTCATATTTTATGTGACCTGTGCTGGGTATTTTGGAGTCATGTTT TTTCTGAACATTGCCATGTTCATTGTGGTAATGGTGCAGATCTGTGGGAGGAATGGCAAGAGAAGCAACCGGACCCTGAGAGAAGAAGTGTTAAGGAACC TGCGCAGTGTGGTTAGCTTGACCTTTCTGTTGGGCATGACATGGGGTTTTGCATTCTTTGCCTGGGGACCCTTAAATATCCCCTTCATGTACCTCTTCTC CATCTTCAATTCATTACAAGGCTTATTTATATTCATCTTCCACTGTGCTATGAAGGAGAATGTTCAGAAACAGTGGCGGCAGCATCTCTGCTGTGGTAGA TTTCGGTTAGCAGATAACTCAGATTGGAGTAAGACAGCTACCAATATCATCAAGAAAAGTTCTGATAATCTAGGAAAATCTTTGTCTTCAAGCTCCATTG GTTCCAACTCAACCTATCTTACATCCAAATCTAAATCCAGCTCTACCACCTATTTCAAAAGGAATAGCCACACAGACAGTGCTTCCATGGACAAGTCCTT GTCAAAACTGGCCCATGCTGATGGAGATCAAACATCAATCATCCCTGTCCATCAGGTCATTGATAAGGTCAAGGGTTATTGCAATGCTCATTCAGACAAC TTCTATAAAAATATTATCATGTCAGACACCTTCAGCCACAGCACAAAGTTTTAATGTCTTTAAGAAAAAGAAATCAATCTGCAGAAATGTGAAGATTTGC AAGCAGTGTAAACTGCAACTAGTGATGTAAATGTGCTATTACCTAGGTAACTGCATATATATAAGGAATGTATTTTGTTAAGAAGGCTTTTGTGAAATTC AGAATTTTTCTTTTTAATATATTTCTTCCATGGAAGAGTTGTCATCACTAAAACTTCAGTACTGAGAGTAACATGACTCAGTAGCCACAGAAGCTATGAT TTGTAAAATATATAATTGAATCAGAGTAATCATAATGCAGGGGAGACATTCAAATTAGAGACAAGGGAGAAGCAATGCTGAGGAAGACCCTAGATAGAGC TCATTTTACTCCACCTAATCGTTATATCTGGATATACCCATTTTCTGCATCTTCTTTCTCAACAATAAAAAATGTAACTATTTTGAATGCCCACAAATCC CATTCCAGTGTTACTTTCTGTGAATGCAGTACCATATTCTCATTTTCAATGACATTTCAACCACAGGCAGAAAAGACTGTTTACTCCTTGACCCAAAGAT TAAAAAGGATTTTTTATTATTTTAAATATTACACCTTCAGAACCATAACATGCTTAAGAAAACTTTCCCAAAATGTTGACCTAGTTAAATGAGGCTATAT AAATTTCTAATATTTTACTTATTCTATTCAAGGCATAGGGCCAAAGCATTAAGTATAATTTAATCCCATACATTCGAGTTAAGTTTAGTGTTGATGTTCC ATCATTCTGGACCTCCCAGGAGTTGTTTAAGAATGAATCTCTTACACCTCTACTTTTGCCCCTCTACTGTATATTAAGCCCATAGGCTTGTGGGAGGAAG GAGAATTTCCATTAGGCAAGCTGTATGCAGTGGAATTTTCCTTTTAGGAGACACACAATTAAGACTCTCTGGTTCTGTCCTTGCTTTGGAGACTTTAAGA CATTTCCTAAAGCACAAATAAAAGCCTCGTATTTCCCCATTGAGAGTTTTGTTCCAAGGAATATGAAGTGAGACATATGGGTGAGTCATAATAATCAAAA TAATTTATGAAGAGCTGGGTCTGCAATAGCTAGTCTAAAAACTACTTGTGTGTCAGTCCTCTGGTTATAGTATATAAGAGCCTGAGGAGGTCTGGCAAGA TAGATGGTGTATTATTTATGGATCAGGCTGCTGCATACAAACCTTGCATACTATTATGCAGCTTACCTAACTCTCAGACTATTCTGAGTAATGCTTGCTT GCTAATGAATGTATAGGAGACCACATTGTAATTGTTCTTAGATGATGGAGTCCATGCAGTTTCTTAGAAATCGGTCTCAGTGCATGCTGTGCTTTTTCAC ATTTGCTCTGGGTTATCTGGGAAGTATCAGGTTCTGGGAGGCAACAGCATTAAGTGATAAGAAAAGGAGACATTCTGGCAAAGCCAATCTGCTTAAAGGC AAAGTCCAGAACCTGGAACCTAGAGGCCTTTCTCTCTGCACGAAAAACAGGTAGTTTGCAGTCTGAGATATGGGAGAGCTTTTAGGCTACACAGCAACCC AAGGGACCTCTCACCTTTTGCTGAGCTTCAATCAGGAAGCTATTTGCCTGGCTCCAGCAGATGATGAGATAATGAGGTAGTGGGTTTTTTATTACTGTTC CATTTTGCAACATCCTGCAACACCATCCTGGGAGACAAGAGCATTACCCAGCTTGGCTTTCACGGGGGAGGGTTGTATTCAGTAAAAAAGAATAGTAAAT ATAAGGTCACTGAGATTCTAAGTAAGATAGTAAATCTAAGGTCACTGAGCCAAATCCTTTTCAATAGGCATATATTAACAGGCTGCTTATTTTGGCGGAG GTTACATATGGATGAAAATGAATCTTAGTCACTGAATATTCATATACATTTCCCCCAAAACCTTAGACATTCATAGTAGATTTTAATTAGTTAGCTTTCT AACTAGTCAGATTTCTGCCCAAAGTGCTTAGTCAATAGTAATTAAGATATAGCTTCAAAAATGGCTTTGCTTTTGATTTCTACTCATATTCGTATGGCTC CAGAAAAATATTTTTTTCATATTTGACAATGTCAGCTCCACTTTAGAAATTTTCAATAACCAGATGAGAAAAAAATTAAGAAATTGCTCAAGGGAAACAT TTGTAAATGGATTTGAAAGATTGAGCCAAATTCTGTTGTCAGTTCTAAGCATGCAGTTCTCACCTCCATTTAGTCCCCCATCAGAACAGAGGTCAGGAAT TTAGCTGGGGAGCCTAAATTTAGTTCAGCTTACCTTTGAGAATAGCATCAATTCAGACTCTCTTTTCATTATGTTTTCTTTTCTTTTTCCCTCTTTTTAA ACTACATTGTGTTAGAGTCATAGTCTAGGATCCTGAGAGATTTTCCATTCTTGTCACCATTCACTTGCATTGTAAAGATTTTCTTTGTCTGTTGTTGGCA TAGATTCTTTTGTACATATTTATTTATTTGTGTTTATATATGTCAATTGGTTTCCTTTCTTAGCTTGATATTGCCTAGCTTTGTTGTTTTAATTAACTTT CTATTAGAGAGACTGTATATATTTTTTCTAAATACTTTGTGAAATCATTTTTGGTAGCAATATCTTTGAATATGATGAATAAAAGTGACTGTGAGTGCAA ATAGAATTAGCAGTAAGAAGCTACTCTAGCTAATTTGCCATTTTACTTAAATGGAAAATGTTTTTCAAATAAATACTTATGTTGTTC

refseq_GPR126.F3 (forward primer)
refseq_GPR126.R3 (reverse primer)
Single exon skipping

Frame 0

PST*GGGRVPPPASGGEDLRRAPLPGPVSSAPA PRTPYFLSFSPSPCQLPCEEGPAASLLPRPQALR *TLPRPGFTLRRRESP*TLQKRRKGGSRRGAGL GRLGSPWVEQRQQSGKVVEDDLAAKGDLGAVMS T*CFAQIECGAAIGNGSPVLSCSYLLYISCVFLT QCGDVPTAEWFCPTLLGPLLLHATLTTTQTARL ACGRSEPPPVISFR*HLTTLTLKKLPIAFMTHY PLIMERARLNFVEQLPKAYHLTQVRMRCMCPFQV TLASRRKVSMPATSELPCP*GIKRSFYPRHQML TRYLLQKASLFQSSVLSHSALKQPKLAMKTVIG QLSPTQMHPSHNCSVLERPRVATFYPFLIQNVC* IMHYLSKKKKTFLQKALNSSALFGIILWALLV* ISKETMKQFHVILPLVKLFLGMGNCCWAPIKMK LSL*KGTFITFDFGILP*MPKSSPTSAVM*KGM* STGKMTSGISQT*L*KLKAT*AVVPT*SRSQQQ NWPAVQTWGPSVKLL*TLLVLHHPLSPLTCLLL TESINKGMMELSIEYP**FRTSFVTLR*KYRARW QNGSIQPSKIGTTRFMSLISVFT*VLERTRLKS REALRMSQGWCFGPF*FTMLPTILIWKEKSFSR SS*KIMSPWMKA*GYIQ*M*DNWVIVLPWRNPKA TTGHLSNLLNTFFLVQTSLAFLLLGYVFTMLPT HW*PTGDLLISPTV*KKQMKLLTRF*I*LLMGR T*PQPILPTLWNRSKEL*IKKKTLI*HLAQL**I YFLIS*AVQTVTCLSHLLKL*KQLMNWPSR*T* IAHHM*ILQLGTWLSAYHPCYQGQMQFQILALV FQAIMNRISRWILRVDKWIHWHL*FCLQTYLRI* VQKILY*LEEHSLLSSTKLDFSRM*DPKEKL** VM*WRAVLETLLSRI*RILFK*KSNIQELRKCI IPSVPSGI*TKTKVLEDGTRQDVLHTEIQMQVRQ SACVTTSHTLEF*WTFQEVPHS*MQETLKSSLS SAILGVEYLLFFQQQLS*HMLLLRNCEGIIPPK S**T*AQPCCS*ISSSS*MAGSPPSMWMDFALLL QSCCISSFWQPLPGWG*KQFTCTLL*LKYLTLT FADTF*NSASLAGVCLP*WCQLF*RAETTMKSM EKKVMGKKKVMNSVGFKIQSYFM*PVLGILESCF F*TLPCSLW*WCRSVGGMAREATGP*EKKC*GT CAVWLA*PFCWA*HGVLHSLPGDP*ISPSCTSS PSSIHYKAYLYSSSTVL*RRMFRNSGGSISAVVD FG*QITQIGVRQLPISSRKVLII*ENLCLQAPL VPTQPILHPNLNPALPPISKGIATQTVLPWTSP CQNWPMLMEIKHQSSLSIRSLIRSRVIAMLIQTT SIKILSCQTPSATAQSFNVFKKKKSICRNVKIC KQCKLQLVM*MCYYLGNCIYIRNVFC*EGFCEI QNFSF*YISSMEELSSLKLQY*E*HDSVATEAMI CKIYN*IRVIIMQGRHSN*RQGRSNAEEDPR*S SFYST*SLYLDIPIFCIFFLNNKKCNYFECPQI PFQCYFL*MQYHILIFNDISTTGRKDCLLLDPKI KKDFLLF*ILHLQNHNMLKKTFPKC*PS*MRLY KFLIFYLFYSRHRAKALSII*SHTFELSLVLMF HHSGPPRSCLRMNLLHLYFCPSTVY*AHRLVGGR RISIRQAVCSGIFLLGDTQLRLSGSVLALETLR HFLKHK*KPRISPLRVLFQGI*SETYG*VIIIK IIYEELGLQ*LV*KLLVCQSSGYSI*EPEEVWQD RWCIIYGSGCCIQTLHTIMQLT*LSDYSE*CLL ANECIGDHIVIVLR*WSPCSFLEIGLSACCAFS HLLWVIWEVSGSGRQQH*VIRKGDILAKPICLKA KSRTWNLEAFLSARKTGSLQSEIWESF*ATQQP KGPLTFC*ASIRKLFAWLQQMMR**GSGFFITV PFCNILQHHPGRQEHYPAWLSRGRVVFSKKE**I *GH*DSK*DSKSKVTEPNPFQ*AYINRLLILAE VTYG*K*ILVTEYSYTFPPKP*TFIVDFN*LAF *LVRFLPKVLSQ**LRYSFKNGFAFDFYSYSYGS RKIFFSYLTMSAPL*KFSITR*EKN*EIAQGKH L*MDLKD*AKFCCQF*ACSSHLHLVPHQNRGQE FSWGA*I*FSLPLRIASIQTLFSLCFLFFFPLFK LHCVRVIV*DPERFSILVTIHLHCKDFLCLLLA *ILLYIFIYLCLYMSIGFLS*LDIA*LCCFN*L SIRETVYIFSKYFVKSFLVAISLNMMNKSDCECK *N*Q*EATLANLPFYLNGKCFSNKYLCC

Frame 1

QVPRVVAESRLPPAGARTCDAHPCLARSPQHQP HAHPTSSASRPHPANFPARRDLPPACFLVRRPC AERCRAQGSPCAVGKAHELSRNGVKEGPAAAQGW GAWVPPGWSSGSRAGKWWRMILRPKGTSAQ*CQ HDVSLRSNVELPLEMEAQSSPVLICFIYHVCSS LSVGMCQLPSGFVQPFWDLYFSMLP*RLPKQPGL HVDAPSPHRLYHSDNI*RL*H*RSSQLHL*LII P**WREPD*ILWSNCQRPII*LKCE*DACVLFK *L*HPEERFQCQLHQSCRVLKESKGHFTPDIRCL PGICCKKHLYSRAQCFHTLL*SNQSWP*RQ*LD SFLLLKCILHTIAQFWKGQEWLLSIHF*FKMFV E*CITCQRKRRHFCRKL*TALPCLE*FFGLYWCK FQKKL*NSSM*FYH**SYSWEWEIVVGLQSK*N CLSKRGHL*LSTLEFYHECQNPLQPQL*CEREC SRLAK*LLEYPKPSSES*KQPKLWFLPDPAPSSR TGQLCRPGDPLSSYCKLS*YYTTHCHH*HACY* QNR*TKE*WNYL*NIRSDSEHPSSP*GKSTEQG GRMAQFNLPKLELHGLCR*YQFSPECWRGQD*SQ EKP*G*AKVGALGPSSLQCYQQY*FGRKNHSAE APKK**VLG*RLEATYSECETTGSLSCHGGTQR LLLAIYPTF*IRSSLSRQAWLFCFSDMFLQCYQP IGNLLGTC*YLQLFKRSK*SC*PDFKFNC*WAE LNLSQYYQHCGTGQKNCE*RRKH*YNTWLNSNE YIF*YLKQFRQ*LA*VIF*SFKNN**IGLQDRPK *HITCEYYNSELGSQRIIPVTRDKCNFKF*HWS SKQ**IVFPDGF*EWTSGSTGICNFASKLT*EF KSRRFCIS*KSTVYFLQQNWTFPGCRTPKKNFSE LCDGVQYWKHYYPESEGSCSNKNQTYKNSGSAS SHLCLLGSEQKQKFWRMEHVRMCCTQRFRCK*D SLPV*PLHTLWSSDGPSKKCLTVRCKKH*SPHFH QLYWVWNICYFFSSNSPDICCF*EIAKGLSLQN LDEPEHSPAVPESPLPPRWLDHLLQCGWTLHCC CSPVAFLPSGNLYLDGARSNSHVHCSS*SI*HLH SPIHSKILHHWLGFACLSGVSCSSEQKQQ*SLW KRKLWERKR**ILLDSRSSHILCDLCWVFWSHV FSEHCHVHCGNGADLWEEWQEKQPDPERRSVKEP AQCG*LDLSVGHDMGFCILCLGTLKYPLHVPLL HLQFITRLIYIHLPLCYEGECSETVAAASLLW* ISVSR*LRLE*DSYQYHQEKF**SRKIFVFKLHW FQLNLSYIQI*IQLYHLFQKE*PHRQCFHGQVL VKTGPC*WRSNINHPCPSGH**GQGLLQCSFRQ LL*KYYHVRHLQPQHKVLMSLRKRNQSAEM*RFA SSVNCN**CKCAIT*VTAYI*GMYFVKKAFVKF RIFLFNIFLPWKSCHH*NFSTESNMTQ*PQKL* FVKYIIESE*S*CRGDIQIRDKGEAMLRKTLDRA HFTPPNRYIWIYPFSASSFSTIKNVTILNAHKS HSSVTFCECSTIFSFSMTFQPQAEKTVYSLTQR LKRIFYYFKYYTFRTITCLRKLSQNVDLVK*GYI NF*YFTYSIQGIGPKH*V*FNPIHSS*V*C*CS IILDLPGVV*E*ISYTSTFAPLLYIKPIGLWEE GEFPLGKLYAVEFSF*ETHN*DSLVLSLLWRL*D IS*STNKSLVFPH*EFCSKEYEVRHMGES**SK *FMKSWVCNS*SKNYLCVSPLVIVYKSLRRSGK IDGVLFMDQAAAYKPCILLCSLPNSQTILSNACL LMNV*ETTL*LFLDDGVHAVS*KSVSVHAVLFH ICSGLSGKYQVLGGNSIK**EKETFWQSQSA*R QSPEPGT*RPFSLHEKQVVCSLRYGRAFRLHSNP RDLSPFAELQSGSYLPGSSR**DNEVVGFLLLF HFATSCNTILGDKSITQLGFHGGGLYSVKKNSK YKVTEILSKIVNLRSLSQILFNRHILTGCLFWRR LHMDENES*SLNIHIHFPQNLRHS**ILIS*LS N*SDFCPKCLVNSN*DIASKMALLLISTHIRMA PEKYFFHI*QCQLHFRNFQ*PDEKKIKKLLKGNI CKWI*KIEPNSVVSSKHAVLTSI*SPIRTEVRN LAGEPKFSSAYL*E*HQFRLSFHYVFFSFSLFL NYIVLES*SRILRDFPFLSPFTCIVKIFFVCCWH RFFCTYLFICVYICQLVSFLSLILPSFVVLINF LLERLYIFFLNTL*NHFW*QYL*I**IKVTVSA NRISSKKLL*LICHFT*MENVFQINTYVV

Frame 2

KYLGWWPSPASRQRGRGPATRTPAWPGLLSTSP THTLLPQLLALTLPTSLRGGTCRQPASSSAGPA LNAAAPRVHLAPSGKPMNSPETA*RRVPPRRRA GAPGFPLGGAAAAERESGGG*SCGQRGPRRSNVN MMFRSDRMWSCHWKWKPSPLLFLFALYIMCVPH SVWGCANCRVVLSNPSGTFTSPCYPNDYPNSQA CMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS LDNGESQTKFCGATAKGLSFNSSANEMHVSFSS DFSIQKKGFNASYIRVAVSLRNQKVILPQTSDA YQVSVAKSISIPELSAFTLCFEATKVGHEDSDWT AFSYSNASFTQLLSFGKAKSGYFLSISDSKCLL NNALPVKEKEDIFAESFEQLCLVWNNSLGSIGV NFKRNYETVPCDSTISKVIPGNGKLLLGSNQNEI VSLKGDIYNFRLWNFTMNAKILSNLSCNVKGNV VDWQNDFWNIPNLALKAESNLSCGSYLIPLPAA ELASCADLGTLCQATVNSPSTTPPTVTTNMPVTN RIDKQRNDGIIYRISVVIQNILRHPEVKVQSKV AEWLNSTFQNWNYTVYVVNISFHLSAGEDKIKV KRSLEDEPRLVLWALLVYNATNNTNLEGKIIQQK LLKNNESLDEGLRLHTVNVRQLGHCLAMEEPKG YYWPSIQPSEYVLPCPDKPGFSASRICFYNATN PLVTYWGPVDISNCLKEANEVANQILNLTADGQN LTSANITNIVEQVKRIVNKEENIDITLGSTLMN IFSNILSSSDSDLLESSSEALKTIDELAFKIDL NSTSHVNITTRNLALSVSSLLPGTNAISNFSIGL PSNNESYFQMDFESGQVDPLASVILPPNLLENL SPEDSVLVRRAQFTFFNKTGLFQDVGPQRKTLV SYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHH PICAFWDLNKNKSFGGWNTSGCVAHRDSDASET VCLCNHFTHFGVLMDLPRSASQLDARNTKVLTF ISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKI LMNLSTALLFLNLLFLLDGWITSFNVDGLCIAV AVLLHFFLLATFTWMGLEAIHMYIALVKVFNTY IRRYILKFCIIGWGLPALVVSVVLASRNNNEVYG KESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMF FLNIAMFIVVMVQICGRNGKRSNRTLREEVLRN LRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFS IFNSLQGLFIFIFHCAMKENVQKQWRQHLCCGR FRLADNSDWSKTATNIIKKSSDNLGKSLSSSSI GSNSTYLTSKSKSSSTTYFKRNSHTDSASMDKSL SKLAHADGDQTSIIPVHQVIDKVKGYCNAHSDN FYKNIIMSDTFSHSTKF*CL*EKEINLQKCEDL QAV*TATSDVNVLLPR*LHIYKECILLRRLL*NS EFFFLIYFFHGRVVITKTSVLRVT*LSSHRSYD L*NI*LNQSNHNAGETFKLETREKQC*GRP*IE LILLHLIVISGYTHFLHLLSQQ*KM*LF*MPTNP IPVLLSVNAVPYSHFQ*HFNHRQKRLFTP*PKD *KGFFIILNITPSEP*HA*ENFPKMLT*LNEAI *ISNILLILFKA*GQSIKYNLIPYIRVKFSVDVP SFWTSQELFKNESLTPLLLPLYCILSP*ACGRK ENFH*ASCMQWNFPFRRHTIKTLWFCPCFGDFK TFPKAQIKASYFPIESFVPRNMK*DIWVSHNNQN NL*RAGSAIASLKTTCVSVLWL*YIRA*GGLAR *MVYYLWIRLLHTNLAYYYAAYLTLRLF*VMLA C**MYRRPHCNCS*MMESMQFLRNRSQCMLCFFT FALGYLGSIRFWEATALSDKKRRHSGKANLLKG KVQNLEPRGLSLCTKNR*FAV*DMGELLGYTAT QGTSHLLLSFNQEAICLAPADDEIMR*WVFYYCS ILQHPATPSWETRALPSLAFTGEGCIQ*KRIVN IRSLRF*VR**I*GH*AKSFSIGIY*QAAYFGG GYIWMKMNLSH*IFIYISPKTLDIHSRF*LVSFL TSQISAQSA*SIVIKI*LQKWLCF*FLLIFVWL QKNIFFIFDNVSSTLEIFNNQMRKKLRNCSRET FVNGFERLSQILLSVLSMQFSPPFSPPSEQRSGI *LGSLNLVQLTFENSINSDSLFIMFSFLFPSF* TTLC*SHSLGS*EIFHSCHHSLAL*RFSLSVVG IDSFVHIYLFVFIYVNWFPFLA*YCLALLF*LTF Y*RDCIYFF*ILCEIIFGSNIFEYDE*K*L*VQ IELAVRSYSS*FAILLKWKMFFK*ILMLF

Sequence NM_001032395

CCAAGTACCTAGGGTGGTGGCCGAGTCCCGCCTCCCGCCAGCGGGGGCGAGGACCTGCGACGCGCACCCCTGCCTGGCCCGGTCTCCTCAGCACCAGCCC CACGCACACCCTACTTCCTCAGCTTCTCGCCCTCACCCTGCCAACTTCCCTGCGAGGAGGGACCTGCCGCCAGCCTGCTTCCTCGTCCGCAGGCCCTGCG CTGAACGCTGCCGCGCCCAGGGTTCACCTTGCGCCGTCGGGAAAGCCCATGAACTCTCCAGAAACGGCGTAAAGGAGGGTCCCGCCGCGGCGCAGGGCTG GGGCGCCTGGGTTCCCCCTGGGTGGAGCAGCGGCAGCAGAGCGGGAAAGTGGTGGAGGATGATCTTGCGGCCAAAGGGGACCTCGGCGCAGTAATGTCAA CATGATGTTTCGCTCAGATCGAATGTGGAGCTGCCATTGGAAATGGAAGCCCAGTCCTCTCCTGTTCTTATTTGCTTTATATATCATGTGTGTTCCTCAC TCAGTGTGGGGATGTGCCAACTGCCGAGTGGTTTTGTCCAACCCTTCTGGGACCTTTACTTCTCCATGCTACCCTAACGACTACCCAAACAGCCAGGCTT GCATGTGGACGCTCCGAGCCCCCACCGGTTATATCATTCAGATAACATTTAACGACTTTGACATTGAAGAAGCTCCCAATTGCATTTATGACTCATTATC CCTTGATAATGGAGAGAGCCAGACTAAATTTTGTGGAGCAACTGCCAAAGGCCTATCATTTAACTCAAGTGCGAATGAGATGCATGTGTCCTTTTCAAGT GACTTTAGCATCCAGAAGAAAGGTTTCAATGCCAGCTACATCAGAGTTGCCGTGTCCTTAAGGAATCAAAAGGTCATTTTACCCCAGACATCAGATGCTT ACCAGGTATCTGTTGCAAAAAGCATCTCTATTCCAGAGCTCAGTGCTTTCACACTCTGCTTTGAAGCAACCAAAGTTGGCCATGAAGACAGTGATTGGAC AGCTTTCTCCTACTCAAATGCATCCTTCACACAATTGCTCAGTTTTGGAAAGGCCAAGAGTGGCTACTTTCTATCCATTTCTGATTCAAAATGTTTGTTG AATAATGCATTACCTGTCAAAGAAAAAGAAGACATTTTTGCAGAAAGCTTTGAACAGCTCTGCCTTGTTTGGAATAATTCTTTGGGCTCTATTGGTGTAA ATTTCAAAAGAAACTATGAAACAGTTCCATGTGATTCTACCATTAGTAAAGTTATTCCTGGGAATGGGAAATTGTTGTTGGGCTCCAATCAAAATGAAAT TGTCTCTCTAAAAGGGGACATTTATAACTTTCGACTTTGGAATTTTACCATGAATGCCAAAATCCTCTCCAACCTCAGCTGTAATGTGAAAGGGAATGTA GTCGACTGGCAAAATGACTTCTGGAATATCCCAAACCTAGCTCTGAAAGCTGAAAGCAACCTAAGCTGTGGTTCCTACCTGATCCCGCTCCCAGCAGCAG AACTGGCCAGCTGTGCAGACCTGGGGACCCTCTGTCAAGATGGAATTATCTATAGAATATCCGTAGTGATTCAGAACATCCTTCGTCACCCTGAGGTAAA AGTACAGAGCAAGGTGGCAGAATGGCTCAATTCAACCTTCCAAAATTGGAACTACACGGTTTATGTCGTTAATATCAGTTTTCACCTGAGTGCTGGAGAG GACAAGATTAAAGTCAAGAGAAGCCTTGAGGATGAGCCAAGGTTGGTGCTTTGGGCCCTTCTAGTTTACAATGCTACCAACAATACTAATTTGGAAGGAA AAATCATTCAGCAGAAGCTCCTAAAAAATAATGAGTCCTTGGATGAAGGCTTGAGGCTACATACAGTGAATGTGAGACAACTGGGTCATTGTCTTGCCAT GGAGGAACCCAAAGGCTACTACTGGCCATCTATCCAACCTTCTGAATACGTTCTTCCTTGTCCAGACAAGCCTGGCTTTTCTGCTTCTCGGATATGTTTT TACAATGCTACCAACCCATTGGTAACCTACTGGGGACCTGTTGATATCTCCAACTGTTTAAAAGAAGCAAATGAAGTTGCTAACCAGATTTTAAATTTAA CTGCTGATGGGCAGAACTTAACCTCAGCCAATATTACCAACATTGTGGAACAGGTCAAAAGAATTGTGAATAAAGAAGAAAACATTGATATAACACTTGG CTCAACTCTAATGAATATATTTTCTAATATCTTAAGCAGTTCAGACAGTGACTTGCTTGAGTCATCTTCTGAAGCTTTAAAAACAATTGATGAATTGGCC TTCAAGATAGACCTAAATAGCACATCACATGTGAATATTACAACTCGGAACTTGGCTCTCAGCGTATCATCCCTGTTACCAGGGACAAATGCAATTTCAA ATTTTAGCATTGGTCTTCCAAGCAATAATGAATCGTATTTCCAGATGGATTTTGAGAGTGGACAAGTGGATCCACTGGCATCTGTAATTTTGCCTCCAAA CTTACTTGAGAATTTAAGTCCAGAAGATTCTGTATTAGTTAGAAGAGCACAGTTTACTTTCTTCAACAAAACTGGACTTTTCCAGGATGTAGGACCCCAA AGAAAAACTTTAGTGAGTTATGTGATGGCGTGCAGTATTGGAAACATTACTATCCAGAATCTGAAGGATCCTGTTCAAATAAAAATCAAACATACAAGAA CTCAGGAAGTGCATCATCCCATCTGTGCCTTCTGGGATCTGAACAAAAACAAAAGTTTTGGAGGATGGAACACGTCAGGATGTGTTGCACACAGAGATTC AGATGCAAGTGAGACAGTCTGCCTGTGTAACCACTTCACACACTTTGGAGTTCTGATGGACCTTCCAAGAAGTGCCTCACAGTTAGATGCAAGAAACACT AAAGTCCTCACTTTCATCAGCTATATTGGGTGTGGAATATCTGCTATTTTTTCAGCAGCAACTCTCCTGACATATGTTGCTTTTGAGAAATTGCGAAGGG ATTATCCCTCCAAAATCTTGATGAACCTGAGCACAGCCCTGCTGTTCCTGAATCTCCTCTTCCTCCTAGATGGCTGGATCACCTCCTTCAATGTGGATGG ACTTTGCATTGCTGTTGCAGTCCTGTTGCATTTCTTCCTTCTGGCAACCTTTACCTGGATGGGGCTAGAAGCAATTCACATGTACATTGCTCTAGTTAAA GTATTTAACACTTACATTCGCCGATACATTCTAAAATTCTGCATCATTGGCTGGGGTTTGCCTGCCTTAGTGGTGTCAGTTGTTCTAGCGAGCAGAAACA ACAATGAAGTCTATGGAAAAGAAAGTTATGGGAAAGAAAAAGGTGATGAATTCTGTTGGATTCAAGATCCAGTCATATTTTATGTGACCTGTGCTGGGTA TTTTGGAGTCATGTTTTTTCTGAACATTGCCATGTTCATTGTGGTAATGGTGCAGATCTGTGGGAGGAATGGCAAGAGAAGCAACCGGACCCTGAGAGAA GAAGTGTTAAGGAACCTGCGCAGTGTGGTTAGCTTGACCTTTCTGTTGGGCATGACATGGGGTTTTGCATTCTTTGCCTGGGGACCCTTAAATATCCCCT TCATGTACCTCTTCTCCATCTTCAATTCATTACAAGGCTTATTTATATTCATCTTCCACTGTGCTATGAAGGAGAATGTTCAGAAACAGTGGCGGCAGCA TCTCTGCTGTGGTAGATTTCGGTTAGCAGATAACTCAGATTGGAGTAAGACAGCTACCAATATCATCAAGAAAAGTTCTGATAATCTAGGAAAATCTTTG TCTTCAAGCTCCATTGGTTCCAACTCAACCTATCTTACATCCAAATCTAAATCCAGCTCTACCACCTATTTCAAAAGGAATAGCCACACAGACAGTGCTT CCATGGACAAGTCCTTGTCAAAACTGGCCCATGCTGATGGAGATCAAACATCAATCATCCCTGTCCATCAGGTCATTGATAAGGTCAAGGGTTATTGCAA TGCTCATTCAGACAACTTCTATAAAAATATTATCATGTCAGACACCTTCAGCCACAGCACAAAGTTTTAATGTCTTTAAGAAAAAGAAATCAATCTGCAG AAATGTGAAGATTTGCAAGCAGTGTAAACTGCAACTAGTGATGTAAATGTGCTATTACCTAGGTAACTGCATATATATAAGGAATGTATTTTGTTAAGAA GGCTTTTGTGAAATTCAGAATTTTTCTTTTTAATATATTTCTTCCATGGAAGAGTTGTCATCACTAAAACTTCAGTACTGAGAGTAACATGACTCAGTAG CCACAGAAGCTATGATTTGTAAAATATATAATTGAATCAGAGTAATCATAATGCAGGGGAGACATTCAAATTAGAGACAAGGGAGAAGCAATGCTGAGGA AGACCCTAGATAGAGCTCATTTTACTCCACCTAATCGTTATATCTGGATATACCCATTTTCTGCATCTTCTTTCTCAACAATAAAAAATGTAACTATTTT GAATGCCCACAAATCCCATTCCAGTGTTACTTTCTGTGAATGCAGTACCATATTCTCATTTTCAATGACATTTCAACCACAGGCAGAAAAGACTGTTTAC TCCTTGACCCAAAGATTAAAAAGGATTTTTTATTATTTTAAATATTACACCTTCAGAACCATAACATGCTTAAGAAAACTTTCCCAAAATGTTGACCTAG TTAAATGAGGCTATATAAATTTCTAATATTTTACTTATTCTATTCAAGGCATAGGGCCAAAGCATTAAGTATAATTTAATCCCATACATTCGAGTTAAGT TTAGTGTTGATGTTCCATCATTCTGGACCTCCCAGGAGTTGTTTAAGAATGAATCTCTTACACCTCTACTTTTGCCCCTCTACTGTATATTAAGCCCATA GGCTTGTGGGAGGAAGGAGAATTTCCATTAGGCAAGCTGTATGCAGTGGAATTTTCCTTTTAGGAGACACACAATTAAGACTCTCTGGTTCTGTCCTTGC TTTGGAGACTTTAAGACATTTCCTAAAGCACAAATAAAAGCCTCGTATTTCCCCATTGAGAGTTTTGTTCCAAGGAATATGAAGTGAGACATATGGGTGA GTCATAATAATCAAAATAATTTATGAAGAGCTGGGTCTGCAATAGCTAGTCTAAAAACTACTTGTGTGTCAGTCCTCTGGTTATAGTATATAAGAGCCTG AGGAGGTCTGGCAAGATAGATGGTGTATTATTTATGGATCAGGCTGCTGCATACAAACCTTGCATACTATTATGCAGCTTACCTAACTCTCAGACTATTC TGAGTAATGCTTGCTTGCTAATGAATGTATAGGAGACCACATTGTAATTGTTCTTAGATGATGGAGTCCATGCAGTTTCTTAGAAATCGGTCTCAGTGCA TGCTGTGCTTTTTCACATTTGCTCTGGGTTATCTGGGAAGTATCAGGTTCTGGGAGGCAACAGCATTAAGTGATAAGAAAAGGAGACATTCTGGCAAAGC CAATCTGCTTAAAGGCAAAGTCCAGAACCTGGAACCTAGAGGCCTTTCTCTCTGCACGAAAAACAGGTAGTTTGCAGTCTGAGATATGGGAGAGCTTTTA GGCTACACAGCAACCCAAGGGACCTCTCACCTTTTGCTGAGCTTCAATCAGGAAGCTATTTGCCTGGCTCCAGCAGATGATGAGATAATGAGGTAGTGGG TTTTTTATTACTGTTCCATTTTGCAACATCCTGCAACACCATCCTGGGAGACAAGAGCATTACCCAGCTTGGCTTTCACGGGGGAGGGTTGTATTCAGTA AAAAAGAATAGTAAATATAAGGTCACTGAGATTCTAAGTAAGATAGTAAATCTAAGGTCACTGAGCCAAATCCTTTTCAATAGGCATATATTAACAGGCT GCTTATTTTGGCGGAGGTTACATATGGATGAAAATGAATCTTAGTCACTGAATATTCATATACATTTCCCCCAAAACCTTAGACATTCATAGTAGATTTT AATTAGTTAGCTTTCTAACTAGTCAGATTTCTGCCCAAAGTGCTTAGTCAATAGTAATTAAGATATAGCTTCAAAAATGGCTTTGCTTTTGATTTCTACT CATATTCGTATGGCTCCAGAAAAATATTTTTTTCATATTTGACAATGTCAGCTCCACTTTAGAAATTTTCAATAACCAGATGAGAAAAAAATTAAGAAAT TGCTCAAGGGAAACATTTGTAAATGGATTTGAAAGATTGAGCCAAATTCTGTTGTCAGTTCTAAGCATGCAGTTCTCACCTCCATTTAGTCCCCCATCAG AACAGAGGTCAGGAATTTAGCTGGGGAGCCTAAATTTAGTTCAGCTTACCTTTGAGAATAGCATCAATTCAGACTCTCTTTTCATTATGTTTTCTTTTCT TTTTCCCTCTTTTTAAACTACATTGTGTTAGAGTCATAGTCTAGGATCCTGAGAGATTTTCCATTCTTGTCACCATTCACTTGCATTGTAAAGATTTTCT TTGTCTGTTGTTGGCATAGATTCTTTTGTACATATTTATTTATTTGTGTTTATATATGTCAATTGGTTTCCTTTCTTAGCTTGATATTGCCTAGCTTTGT TGTTTTAATTAACTTTCTATTAGAGAGACTGTATATATTTTTTCTAAATACTTTGTGAAATCATTTTTGGTAGCAATATCTTTGAATATGATGAATAAAA GTGACTGTGAGTGCAAATAGAATTAGCAGTAAGAAGCTACTCTAGCTAATTTGCCATTTTACTTAAATGGAAAATGTTTTTCAAATAAATACTTATGTTG TTC

refseq_GPR126.F3 (forward primer)
refseq_GPR126.R3 (reverse primer)
Single exon skipping

Frame 0

PST*GGGRVPPPASGGEDLRRAPLPGPVSSAPA PRTPYFLSFSPSPCQLPCEEGPAASLLPRPQALR *TLPRPGFTLRRRESP*TLQKRRKGGSRRGAGL GRLGSPWVEQRQQSGKVVEDDLAAKGDLGAVMS T*CFAQIECGAAIGNGSPVLSCSYLLYISCVFLT QCGDVPTAEWFCPTLLGPLLLHATLTTTQTARL ACGRSEPPPVISFR*HLTTLTLKKLPIAFMTHY PLIMERARLNFVEQLPKAYHLTQVRMRCMCPFQV TLASRRKVSMPATSELPCP*GIKRSFYPRHQML TRYLLQKASLFQSSVLSHSALKQPKLAMKTVIG QLSPTQMHPSHNCSVLERPRVATFYPFLIQNVC* IMHYLSKKKKTFLQKALNSSALFGIILWALLV* ISKETMKQFHVILPLVKLFLGMGNCCWAPIKMK LSL*KGTFITFDFGILP*MPKSSPTSAVM*KGM* STGKMTSGISQT*L*KLKAT*AVVPT*SRSQQQ NWPAVQTWGPSVKMELSIEYP**FRTSFVTLR* KYRARWQNGSIQPSKIGTTRFMSLISVFT*VLER TRLKSREALRMSQGWCFGPF*FTMLPTILIWKE KSFSRSS*KIMSPWMKA*GYIQ*M*DNWVIVLP WRNPKATTGHLSNLLNTFFLVQTSLAFLLLGYVF TMLPTHW*PTGDLLISPTV*KKQMKLLTRF*I* LLMGRT*PQPILPTLWNRSKEL*IKKKTLI*HL AQL**IYFLIS*AVQTVTCLSHLLKL*KQLMNWP SR*T*IAHHM*ILQLGTWLSAYHPCYQGQMQFQ ILALVFQAIMNRISRWILRVDKWIHWHL*FCLQ TYLRI*VQKILY*LEEHSLLSSTKLDFSRM*DPK EKL**VM*WRAVLETLLSRI*RILFK*KSNIQE LRKCIIPSVPSGI*TKTKVLEDGTRQDVLHTEI QMQVRQSACVTTSHTLEF*WTFQEVPHS*MQETL KSSLSSAILGVEYLLFFQQQLS*HMLLLRNCEG IIPPKS**T*AQPCCS*ISSSS*MAGSPPSMWM DFALLLQSCCISSFWQPLPGWG*KQFTCTLL*LK YLTLTFADTF*NSASLAGVCLP*WCQLF*RAET TMKSMEKKVMGKKKVMNSVGFKIQSYFM*PVLG ILESCFF*TLPCSLW*WCRSVGGMAREATGP*EK KC*GTCAVWLA*PFCWA*HGVLHSLPGDP*ISP SCTSSPSSIHYKAYLYSSSTVL*RRMFRNSGGS ISAVVDFG*QITQIGVRQLPISSRKVLII*ENLC LQAPLVPTQPILHPNLNPALPPISKGIATQTVL PWTSPCQNWPMLMEIKHQSSLSIRSLIRSRVIA MLIQTTSIKILSCQTPSATAQSFNVFKKKKSICR NVKICKQCKLQLVM*MCYYLGNCIYIRNVFC*E GFCEIQNFSF*YISSMEELSSLKLQY*E*HDSV ATEAMICKIYN*IRVIIMQGRHSN*RQGRSNAEE DPR*SSFYST*SLYLDIPIFCIFFLNNKKCNYF ECPQIPFQCYFL*MQYHILIFNDISTTGRKDCL LLDPKIKKDFLLF*ILHLQNHNMLKKTFPKC*PS *MRLYKFLIFYLFYSRHRAKALSII*SHTFELS LVLMFHHSGPPRSCLRMNLLHLYFCPSTVY*AH RLVGGRRISIRQAVCSGIFLLGDTQLRLSGSVLA LETLRHFLKHK*KPRISPLRVLFQGI*SETYG* VIIIKIIYEELGLQ*LV*KLLVCQSSGYSI*EP EEVWQDRWCIIYGSGCCIQTLHTIMQLT*LSDYS E*CLLANECIGDHIVIVLR*WSPCSFLEIGLSA CCAFSHLLWVIWEVSGSGRQQH*VIRKGDILAK PICLKAKSRTWNLEAFLSARKTGSLQSEIWESF* ATQQPKGPLTFC*ASIRKLFAWLQQMMR**GSG FFITVPFCNILQHHPGRQEHYPAWLSRGRVVFS KKE**I*GH*DSK*DSKSKVTEPNPFQ*AYINRL LILAEVTYG*K*ILVTEYSYTFPPKP*TFIVDF N*LAF*LVRFLPKVLSQ**LRYSFKNGFAFDFY SYSYGSRKIFFSYLTMSAPL*KFSITR*EKN*EI AQGKHL*MDLKD*AKFCCQF*ACSSHLHLVPHQ NRGQEFSWGA*I*FSLPLRIASIQTLFSLCFLF FFPLFKLHCVRVIV*DPERFSILVTIHLHCKDFL CLLLA*ILLYIFIYLCLYMSIGFLS*LDIA*LC CFN*LSIRETVYIFSKYFVKSFLVAISLNMMNK SDCECK*N*Q*EATLANLPFYLNGKCFSNKYLCC

Frame 1

QVPRVVAESRLPPAGARTCDAHPCLARSPQHQP HAHPTSSASRPHPANFPARRDLPPACFLVRRPC AERCRAQGSPCAVGKAHELSRNGVKEGPAAAQGW GAWVPPGWSSGSRAGKWWRMILRPKGTSAQ*CQ HDVSLRSNVELPLEMEAQSSPVLICFIYHVCSS LSVGMCQLPSGFVQPFWDLYFSMLP*RLPKQPGL HVDAPSPHRLYHSDNI*RL*H*RSSQLHL*LII P**WREPD*ILWSNCQRPII*LKCE*DACVLFK *L*HPEERFQCQLHQSCRVLKESKGHFTPDIRCL PGICCKKHLYSRAQCFHTLL*SNQSWP*RQ*LD SFLLLKCILHTIAQFWKGQEWLLSIHF*FKMFV E*CITCQRKRRHFCRKL*TALPCLE*FFGLYWCK FQKKL*NSSM*FYH**SYSWEWEIVVGLQSK*N CLSKRGHL*LSTLEFYHECQNPLQPQL*CEREC SRLAK*LLEYPKPSSES*KQPKLWFLPDPAPSSR TGQLCRPGDPLSRWNYL*NIRSDSEHPSSP*GK STEQGGRMAQFNLPKLELHGLCR*YQFSPECWR GQD*SQEKP*G*AKVGALGPSSLQCYQQY*FGRK NHSAEAPKK**VLG*RLEATYSECETTGSLSCH GGTQRLLLAIYPTF*IRSSLSRQAWLFCFSDMF LQCYQPIGNLLGTC*YLQLFKRSK*SC*PDFKFN C*WAELNLSQYYQHCGTGQKNCE*RRKH*YNTW LNSNEYIF*YLKQFRQ*LA*VIF*SFKNN**IG LQDRPK*HITCEYYNSELGSQRIIPVTRDKCNFK F*HWSSKQ**IVFPDGF*EWTSGSTGICNFASK LT*EFKSRRFCIS*KSTVYFLQQNWTFPGCRTP KKNFSELCDGVQYWKHYYPESEGSCSNKNQTYKN SGSASSHLCLLGSEQKQKFWRMEHVRMCCTQRF RCK*DSLPV*PLHTLWSSDGPSKKCLTVRCKKH *SPHFHQLYWVWNICYFFSSNSPDICCF*EIAKG LSLQNLDEPEHSPAVPESPLPPRWLDHLLQCGW TLHCCCSPVAFLPSGNLYLDGARSNSHVHCSS* SI*HLHSPIHSKILHHWLGFACLSGVSCSSEQKQ Q*SLWKRKLWERKR**ILLDSRSSHILCDLCWV FWSHVFSEHCHVHCGNGADLWEEWQEKQPDPER RSVKEPAQCG*LDLSVGHDMGFCILCLGTLKYPL HVPLLHLQFITRLIYIHLPLCYEGECSETVAAA SLLW*ISVSR*LRLE*DSYQYHQEKF**SRKIF VFKLHWFQLNLSYIQI*IQLYHLFQKE*PHRQCF HGQVLVKTGPC*WRSNINHPCPSGH**GQGLLQ CSFRQLL*KYYHVRHLQPQHKVLMSLRKRNQSA EM*RFASSVNCN**CKCAIT*VTAYI*GMYFVKK AFVKFRIFLFNIFLPWKSCHH*NFSTESNMTQ* PQKL*FVKYIIESE*S*CRGDIQIRDKGEAMLR KTLDRAHFTPPNRYIWIYPFSASSFSTIKNVTIL NAHKSHSSVTFCECSTIFSFSMTFQPQAEKTVY SLTQRLKRIFYYFKYYTFRTITCLRKLSQNVDL VK*GYINF*YFTYSIQGIGPKH*V*FNPIHSS*V *C*CSIILDLPGVV*E*ISYTSTFAPLLYIKPI GLWEEGEFPLGKLYAVEFSF*ETHN*DSLVLSL LWRL*DIS*STNKSLVFPH*EFCSKEYEVRHMGE S**SK*FMKSWVCNS*SKNYLCVSPLVIVYKSL RRSGKIDGVLFMDQAAAYKPCILLCSLPNSQTI LSNACLLMNV*ETTL*LFLDDGVHAVS*KSVSVH AVLFHICSGLSGKYQVLGGNSIK**EKETFWQS QSA*RQSPEPGT*RPFSLHEKQVVCSLRYGRAF RLHSNPRDLSPFAELQSGSYLPGSSR**DNEVVG FLLLFHFATSCNTILGDKSITQLGFHGGGLYSV KKNSKYKVTEILSKIVNLRSLSQILFNRHILTG CLFWRRLHMDENES*SLNIHIHFPQNLRHS**IL IS*LSN*SDFCPKCLVNSN*DIASKMALLLIST HIRMAPEKYFFHI*QCQLHFRNFQ*PDEKKIKK LLKGNICKWI*KIEPNSVVSSKHAVLTSI*SPIR TEVRNLAGEPKFSSAYL*E*HQFRLSFHYVFFS FSLFLNYIVLES*SRILRDFPFLSPFTCIVKIF FVCCWHRFFCTYLFICVYICQLVSFLSLILPSFV VLINFLLERLYIFFLNTL*NHFW*QYL*I**IK VTVSANRISSKKLL*LICHFT*MENVFQINTYV V

Frame 2

KYLGWWPSPASRQRGRGPATRTPAWPGLLSTSP THTLLPQLLALTLPTSLRGGTCRQPASSSAGPA LNAAAPRVHLAPSGKPMNSPETA*RRVPPRRRA GAPGFPLGGAAAAERESGGG*SCGQRGPRRSNVN MMFRSDRMWSCHWKWKPSPLLFLFALYIMCVPH SVWGCANCRVVLSNPSGTFTSPCYPNDYPNSQA CMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS LDNGESQTKFCGATAKGLSFNSSANEMHVSFSS DFSIQKKGFNASYIRVAVSLRNQKVILPQTSDA YQVSVAKSISIPELSAFTLCFEATKVGHEDSDWT AFSYSNASFTQLLSFGKAKSGYFLSISDSKCLL NNALPVKEKEDIFAESFEQLCLVWNNSLGSIGV NFKRNYETVPCDSTISKVIPGNGKLLLGSNQNEI VSLKGDIYNFRLWNFTMNAKILSNLSCNVKGNV VDWQNDFWNIPNLALKAESNLSCGSYLIPLPAA ELASCADLGTLCQDGIIYRISVVIQNILRHPEVK VQSKVAEWLNSTFQNWNYTVYVVNISFHLSAGE DKIKVKRSLEDEPRLVLWALLVYNATNNTNLEG KIIQQKLLKNNESLDEGLRLHTVNVRQLGHCLAM EEPKGYYWPSIQPSEYVLPCPDKPGFSASRICF YNATNPLVTYWGPVDISNCLKEANEVANQILNL TADGQNLTSANITNIVEQVKRIVNKEENIDITLG STLMNIFSNILSSSDSDLLESSSEALKTIDELA FKIDLNSTSHVNITTRNLALSVSSLLPGTNAIS NFSIGLPSNNESYFQMDFESGQVDPLASVILPPN LLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQ RKTLVSYVMACSIGNITIQNLKDPVQIKIKHTR TQEVHHPICAFWDLNKNKSFGGWNTSGCVAHRDS DASETVCLCNHFTHFGVLMDLPRSASQLDARNT KVLTFISYIGCGISAIFSAATLLTYVAFEKLRR DYPSKILMNLSTALLFLNLLFLLDGWITSFNVDG LCIAVAVLLHFFLLATFTWMGLEAIHMYIALVK VFNTYIRRYILKFCIIGWGLPALVVSVVLASRN NNEVYGKESYGKEKGDEFCWIQDPVIFYVTCAGY FGVMFFLNIAMFIVVMVQICGRNGKRSNRTLRE EVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIP FMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRQH LCCGRFRLADNSDWSKTATNIIKKSSDNLGKSL SSSSIGSNSTYLTSKSKSSSTTYFKRNSHTDSA SMDKSLSKLAHADGDQTSIIPVHQVIDKVKGYCN AHSDNFYKNIIMSDTFSHSTKF*CL*EKEINLQ KCEDLQAV*TATSDVNVLLPR*LHIYKECILLR RLL*NSEFFFLIYFFHGRVVITKTSVLRVT*LSS HRSYDL*NI*LNQSNHNAGETFKLETREKQC*G RP*IELILLHLIVISGYTHFLHLLSQQ*KM*LF *MPTNPIPVLLSVNAVPYSHFQ*HFNHRQKRLFT P*PKD*KGFFIILNITPSEP*HA*ENFPKMLT* LNEAI*ISNILLILFKA*GQSIKYNLIPYIRVK FSVDVPSFWTSQELFKNESLTPLLLPLYCILSP* ACGRKENFH*ASCMQWNFPFRRHTIKTLWFCPC FGDFKTFPKAQIKASYFPIESFVPRNMK*DIWV SHNNQNNL*RAGSAIASLKTTCVSVLWL*YIRA* GGLAR*MVYYLWIRLLHTNLAYYYAAYLTLRLF *VMLAC**MYRRPHCNCS*MMESMQFLRNRSQC MLCFFTFALGYLGSIRFWEATALSDKKRRHSGKA NLLKGKVQNLEPRGLSLCTKNR*FAV*DMGELL GYTATQGTSHLLLSFNQEAICLAPADDEIMR*W VFYYCSILQHPATPSWETRALPSLAFTGEGCIQ* KRIVNIRSLRF*VR**I*GH*AKSFSIGIY*QA AYFGGGYIWMKMNLSH*IFIYISPKTLDIHSRF *LVSFLTSQISAQSA*SIVIKI*LQKWLCF*FLL IFVWLQKNIFFIFDNVSSTLEIFNNQMRKKLRN CSRETFVNGFERLSQILLSVLSMQFSPPFSPPS EQRSGI*LGSLNLVQLTFENSINSDSLFIMFSFL FPSF*TTLC*SHSLGS*EIFHSCHHSLAL*RFS LSVVGIDSFVHIYLFVFIYVNWFPFLA*YCLAL LF*LTFY*RDCIYFF*ILCEIIFGSNIFEYDE*K *L*VQIELAVRSYSS*FAILLKWKMFFK*ILML F

Sequence NM_001032394

CCAAGTACCTAGGGTGGTGGCCGAGTCCCGCCTCCCGCCAGCGGGGGCGAGGACCTGCGACGCGCACCCCTGCCTGGCCCGGTCTCCTCAGCACCAGCCC CACGCACACCCTACTTCCTCAGCTTCTCGCCCTCACCCTGCCAACTTCCCTGCGAGGAGGGACCTGCCGCCAGCCTGCTTCCTCGTCCGCAGGCCCTGCG CTGAACGCTGCCGCGCCCAGGGTTCACCTTGCGCCGTCGGGAAAGCCCATGAACTCTCCAGAAACGGCGTAAAGGAGGGTCCCGCCGCGGCGCAGGGCTG GGGCGCCTGGGTTCCCCCTGGGTGGAGCAGCGGCAGCAGAGCGGGAAAGTGGTGGAGGATGATCTTGCGGCCAAAGGGGACCTCGGCGCAGTAATGTCAA CATGATGTTTCGCTCAGATCGAATGTGGAGCTGCCATTGGAAATGGAAGCCCAGTCCTCTCCTGTTCTTATTTGCTTTATATATCATGTGTGTTCCTCAC TCAGTGTGGGGATGTGCCAACTGCCGAGTGGTTTTGTCCAACCCTTCTGGGACCTTTACTTCTCCATGCTACCCTAACGACTACCCAAACAGCCAGGCTT GCATGTGGACGCTCCGAGCCCCCACCGGTTATATCATTCAGATAACATTTAACGACTTTGACATTGAAGAAGCTCCCAATTGCATTTATGACTCATTATC CCTTGATAATGGAGAGAGCCAGACTAAATTTTGTGGAGCAACTGCCAAAGGCCTATCATTTAACTCAAGTGCGAATGAGATGCATGTGTCCTTTTCAAGT GACTTTAGCATCCAGAAGAAAGGTTTCAATGCCAGCTACATCAGAGTTGCCGTGTCCTTAAGGAATCAAAAGGTCATTTTACCCCAGACATCAGATGCTT ACCAGGTATCTGTTGCAAAAAGCATCTCTATTCCAGAGCTCAGTGCTTTCACACTCTGCTTTGAAGCAACCAAAGTTGGCCATGAAGACAGTGATTGGAC AGCTTTCTCCTACTCAAATGCATCCTTCACACAATTGCTCAGTTTTGGAAAGGCCAAGAGTGGCTACTTTCTATCCATTTCTGATTCAAAATGTTTGTTG AATAATGCATTACCTGTCAAAGAAAAAGAAGACATTTTTGCAGAAAGCTTTGAACAGCTCTGCCTTGTTTGGAATAATTCTTTGGGCTCTATTGGTGTAA ATTTCAAAAGAAACTATGAAACAGTTCCATGTGATTCTACCATTAGTAAAGTTATTCCTGGGAATGGGAAATTGTTGTTGGGCTCCAATCAAAATGAAAT TGTCTCTCTAAAAGGGGACATTTATAACTTTCGACTTTGGAATTTTACCATGAATGCCAAAATCCTCTCCAACCTCAGCTGTAATGTGAAAGGGAATGTA GTCGACTGGCAAAATGACTTCTGGAATATCCCAAACCTAGCTCTGAAAGCTGAAAGCAACCTAAGCTGTGGTTCCTACCTGATCCCGCTCCCAGCAGCAG AACTGGCCAGCTGTGCAGACCTGGGGACCCTCTGTCAAGATGGAATTATCTATAGAATATCCGTAGTGATTCAGAACATCCTTCGTCACCCTGAGGTAAA AGTACAGAGCAAGGTGGCAGAATGGCTCAATTCAACCTTCCAAAATTGGAACTACACGGTTTATGTCGTTAATATCAGTTTTCACCTGAGTGCTGGAGAG GACAAGATTAAAGTCAAGAGAAGCCTTGAGGATGAGCCAAGGTTGGTGCTTTGGGCCCTTCTAGTTTACAATGCTACCAACAATACTAATTTGGAAGGAA AAATCATTCAGCAGAAGCTCCTAAAAAATAATGAGTCCTTGGATGAAGGCTTGAGGCTACATACAGTGAATGTGAGACAACTGGGTCATTGTCTTGCCAT GGAGGAACCCAAAGGCTACTACTGGCCATCTATCCAACCTTCTGAATACGTTCTTCCTTGTCCAGACAAGCCTGGCTTTTCTGCTTCTCGGATATGTTTT TACAATGCTACCAACCCATTGGTAACCTACTGGGGACCTGTTGATATCTCCAACTGTTTAAAAGAAGCAAATGAAGTTGCTAACCAGATTTTAAATTTAA CTGCTGATGGGCAGAACTTAACCTCAGCCAATATTACCAACATTGTGGAACAGGTCAAAAGAATTGTGAATAAAGAAGAAAACATTGATATAACACTTGG CTCAACTCTAATGAATATATTTTCTAATATCTTAAGCAGTTCAGACAGTGACTTGCTTGAGTCATCTTCTGAAGCTTTAAAAACAATTGATGAATTGGCC TTCAAGATAGACCTAAATAGCACATCACATGTGAATATTACAACTCGGAACTTGGCTCTCAGCGTATCATCCCTGTTACCAGGGACAAATGCAATTTCAA ATTTTAGCATTGGTCTTCCAAGCAATAATGAATCGTATTTCCAGATGGATTTTGAGAGTGGACAAGTGGATCCACTGGCATCTGTAATTTTGCCTCCAAA CTTACTTGAGAATTTAAGTCCAGAAGATTCTGTATTAGTTAGAAGAGCACAGTTTACTTTCTTCAACAAAACTGGACTTTTCCAGGATGTAGGACCCCAA AGAAAAACTTTAGTGAGTTATGTGATGGCGTGCAGTATTGGAAACATTACTATCCAGAATCTGAAGGATCCTGTTCAAATAAAAATCAAACATACAAGAA CTCAGGAAGTGCATCATCCCATCTGTGCCTTCTGGGATCTGAACAAAAACAAAAGTTTTGGAGGATGGAACACGTCAGGATGTGTTGCACACAGAGATTC AGATGCAAGTGAGACAGTCTGCCTGTGTAACCACTTCACACACTTTGGAGTTCTGATGGACCTTCCAAGAAGTGCCTCACAGTTAGATGCAAGAAACACT AAAGTCCTCACTTTCATCAGCTATATTGGGTGTGGAATATCTGCTATTTTTTCAGCAGCAACTCTCCTGACATATGTTGCTTTTGAGAAATTGCGAAGGG ATTATCCCTCCAAAATCTTGATGAACCTGAGCACAGCCCTGCTGTTCCTGAATCTCCTCTTCCTCCTAGATGGCTGGATCACCTCCTTCAATGTGGATGG ACTTTGCATTGCTGTTGCAGTCCTGTTGCATTTCTTCCTTCTGGCAACCTTTACCTGGATGGGGCTAGAAGCAATTCACATGTACATTGCTCTAGTTAAA GTATTTAACACTTACATTCGCCGATACATTCTAAAATTCTGCATCATTGGCTGGGGTTTGCCTGCCTTAGTGGTGTCAGTTGTTCTAGCGAGCAGAAACA ACAATGAAGTCTATGGAAAAGAAAGTTATGGGAAAGAAAAAGGTGATGAATTCTGTTGGATTCAAGATCCAGTCATATTTTATGTGACCTGTGCTGGGTA TTTTGGAGTCATGTTTTTTCTGAACATTGCCATGTTCATTGTGGTAATGGTGCAGATCTGTGGGAGGAATGGCAAGAGAAGCAACCGGACCCTGAGAGAA GAAGTGTTAAGGAACCTGCGCAGTGTGGTTAGCTTGACCTTTCTGTTGGGCATGACATGGGGTTTTGCATTCTTTGCCTGGGGACCCTTAAATATCCCCT TCATGTACCTCTTCTCCATCTTCAATTCATTACAAGGCTTATTTATATTCATCTTCCACTGTGCTATGAAGGAGAATGTTCAGAAACAGTGGCGGCAGCA TCTCTGCTGTGGTAGATTTCGGTTAGCAGATAACTCAGATTGGAGTAAGACAGCTACCAATATCATCAAGAAAAGTTCTGATAATCTAGGAAAATCTTTG TCTTCAAGCTCCATTGGTTCCAACTCAACCTATCTTACATCCAAATCTAAATCCAGCTCTACCACCTATTTCAAAAGGAATAGCCACACAGATAATGTCT CCTATGAGCATTCCTTCAACAAAAGTGGATCACTCAGACAGTGCTTCCATGGACAAGTCCTTGTCAAAACTGGCCCATGCTGATGGAGATCAAACATCAA TCATCCCTGTCCATCAGGTCATTGATAAGGTCAAGGGTTATTGCAATGCTCATTCAGACAACTTCTATAAAAATATTATCATGTCAGACACCTTCAGCCA CAGCACAAAGTTTTAATGTCTTTAAGAAAAAGAAATCAATCTGCAGAAATGTGAAGATTTGCAAGCAGTGTAAACTGCAACTAGTGATGTAAATGTGCTA TTACCTAGGTAACTGCATATATATAAGGAATGTATTTTGTTAAGAAGGCTTTTGTGAAATTCAGAATTTTTCTTTTTAATATATTTCTTCCATGGAAGAG TTGTCATCACTAAAACTTCAGTACTGAGAGTAACATGACTCAGTAGCCACAGAAGCTATGATTTGTAAAATATATAATTGAATCAGAGTAATCATAATGC AGGGGAGACATTCAAATTAGAGACAAGGGAGAAGCAATGCTGAGGAAGACCCTAGATAGAGCTCATTTTACTCCACCTAATCGTTATATCTGGATATACC CATTTTCTGCATCTTCTTTCTCAACAATAAAAAATGTAACTATTTTGAATGCCCACAAATCCCATTCCAGTGTTACTTTCTGTGAATGCAGTACCATATT CTCATTTTCAATGACATTTCAACCACAGGCAGAAAAGACTGTTTACTCCTTGACCCAAAGATTAAAAAGGATTTTTTATTATTTTAAATATTACACCTTC AGAACCATAACATGCTTAAGAAAACTTTCCCAAAATGTTGACCTAGTTAAATGAGGCTATATAAATTTCTAATATTTTACTTATTCTATTCAAGGCATAG GGCCAAAGCATTAAGTATAATTTAATCCCATACATTCGAGTTAAGTTTAGTGTTGATGTTCCATCATTCTGGACCTCCCAGGAGTTGTTTAAGAATGAAT CTCTTACACCTCTACTTTTGCCCCTCTACTGTATATTAAGCCCATAGGCTTGTGGGAGGAAGGAGAATTTCCATTAGGCAAGCTGTATGCAGTGGAATTT TCCTTTTAGGAGACACACAATTAAGACTCTCTGGTTCTGTCCTTGCTTTGGAGACTTTAAGACATTTCCTAAAGCACAAATAAAAGCCTCGTATTTCCCC ATTGAGAGTTTTGTTCCAAGGAATATGAAGTGAGACATATGGGTGAGTCATAATAATCAAAATAATTTATGAAGAGCTGGGTCTGCAATAGCTAGTCTAA AAACTACTTGTGTGTCAGTCCTCTGGTTATAGTATATAAGAGCCTGAGGAGGTCTGGCAAGATAGATGGTGTATTATTTATGGATCAGGCTGCTGCATAC AAACCTTGCATACTATTATGCAGCTTACCTAACTCTCAGACTATTCTGAGTAATGCTTGCTTGCTAATGAATGTATAGGAGACCACATTGTAATTGTTCT TAGATGATGGAGTCCATGCAGTTTCTTAGAAATCGGTCTCAGTGCATGCTGTGCTTTTTCACATTTGCTCTGGGTTATCTGGGAAGTATCAGGTTCTGGG AGGCAACAGCATTAAGTGATAAGAAAAGGAGACATTCTGGCAAAGCCAATCTGCTTAAAGGCAAAGTCCAGAACCTGGAACCTAGAGGCCTTTCTCTCTG CACGAAAAACAGGTAGTTTGCAGTCTGAGATATGGGAGAGCTTTTAGGCTACACAGCAACCCAAGGGACCTCTCACCTTTTGCTGAGCTTCAATCAGGAA GCTATTTGCCTGGCTCCAGCAGATGATGAGATAATGAGGTAGTGGGTTTTTTATTACTGTTCCATTTTGCAACATCCTGCAACACCATCCTGGGAGACAA GAGCATTACCCAGCTTGGCTTTCACGGGGGAGGGTTGTATTCAGTAAAAAAGAATAGTAAATATAAGGTCACTGAGATTCTAAGTAAGATAGTAAATCTA AGGTCACTGAGCCAAATCCTTTTCAATAGGCATATATTAACAGGCTGCTTATTTTGGCGGAGGTTACATATGGATGAAAATGAATCTTAGTCACTGAATA TTCATATACATTTCCCCCAAAACCTTAGACATTCATAGTAGATTTTAATTAGTTAGCTTTCTAACTAGTCAGATTTCTGCCCAAAGTGCTTAGTCAATAG TAATTAAGATATAGCTTCAAAAATGGCTTTGCTTTTGATTTCTACTCATATTCGTATGGCTCCAGAAAAATATTTTTTTCATATTTGACAATGTCAGCTC CACTTTAGAAATTTTCAATAACCAGATGAGAAAAAAATTAAGAAATTGCTCAAGGGAAACATTTGTAAATGGATTTGAAAGATTGAGCCAAATTCTGTTG TCAGTTCTAAGCATGCAGTTCTCACCTCCATTTAGTCCCCCATCAGAACAGAGGTCAGGAATTTAGCTGGGGAGCCTAAATTTAGTTCAGCTTACCTTTG AGAATAGCATCAATTCAGACTCTCTTTTCATTATGTTTTCTTTTCTTTTTCCCTCTTTTTAAACTACATTGTGTTAGAGTCATAGTCTAGGATCCTGAGA GATTTTCCATTCTTGTCACCATTCACTTGCATTGTAAAGATTTTCTTTGTCTGTTGTTGGCATAGATTCTTTTGTACATATTTATTTATTTGTGTTTATA TATGTCAATTGGTTTCCTTTCTTAGCTTGATATTGCCTAGCTTTGTTGTTTTAATTAACTTTCTATTAGAGAGACTGTATATATTTTTTCTAAATACTTT GTGAAATCATTTTTGGTAGCAATATCTTTGAATATGATGAATAAAAGTGACTGTGAGTGCAAATAGAATTAGCAGTAAGAAGCTACTCTAGCTAATTTGC CATTTTACTTAAATGGAAAATGTTTTTCAAATAAATACTTATGTTGTTC

refseq_GPR126.F3 (forward primer)
refseq_GPR126.R3 (reverse primer)
Single exon skipping

Frame 0

PST*GGGRVPPPASGGEDLRRAPLPGPVSSAPA PRTPYFLSFSPSPCQLPCEEGPAASLLPRPQALR *TLPRPGFTLRRRESP*TLQKRRKGGSRRGAGL GRLGSPWVEQRQQSGKVVEDDLAAKGDLGAVMS T*CFAQIECGAAIGNGSPVLSCSYLLYISCVFLT QCGDVPTAEWFCPTLLGPLLLHATLTTTQTARL ACGRSEPPPVISFR*HLTTLTLKKLPIAFMTHY PLIMERARLNFVEQLPKAYHLTQVRMRCMCPFQV TLASRRKVSMPATSELPCP*GIKRSFYPRHQML TRYLLQKASLFQSSVLSHSALKQPKLAMKTVIG QLSPTQMHPSHNCSVLERPRVATFYPFLIQNVC* IMHYLSKKKKTFLQKALNSSALFGIILWALLV* ISKETMKQFHVILPLVKLFLGMGNCCWAPIKMK LSL*KGTFITFDFGILP*MPKSSPTSAVM*KGM* STGKMTSGISQT*L*KLKAT*AVVPT*SRSQQQ NWPAVQTWGPSVKMELSIEYP**FRTSFVTLR* KYRARWQNGSIQPSKIGTTRFMSLISVFT*VLER TRLKSREALRMSQGWCFGPF*FTMLPTILIWKE KSFSRSS*KIMSPWMKA*GYIQ*M*DNWVIVLP WRNPKATTGHLSNLLNTFFLVQTSLAFLLLGYVF TMLPTHW*PTGDLLISPTV*KKQMKLLTRF*I* LLMGRT*PQPILPTLWNRSKEL*IKKKTLI*HL AQL**IYFLIS*AVQTVTCLSHLLKL*KQLMNWP SR*T*IAHHM*ILQLGTWLSAYHPCYQGQMQFQ ILALVFQAIMNRISRWILRVDKWIHWHL*FCLQ TYLRI*VQKILY*LEEHSLLSSTKLDFSRM*DPK EKL**VM*WRAVLETLLSRI*RILFK*KSNIQE LRKCIIPSVPSGI*TKTKVLEDGTRQDVLHTEI QMQVRQSACVTTSHTLEF*WTFQEVPHS*MQETL KSSLSSAILGVEYLLFFQQQLS*HMLLLRNCEG IIPPKS**T*AQPCCS*ISSSS*MAGSPPSMWM DFALLLQSCCISSFWQPLPGWG*KQFTCTLL*LK YLTLTFADTF*NSASLAGVCLP*WCQLF*RAET TMKSMEKKVMGKKKVMNSVGFKIQSYFM*PVLG ILESCFF*TLPCSLW*WCRSVGGMAREATGP*EK KC*GTCAVWLA*PFCWA*HGVLHSLPGDP*ISP SCTSSPSSIHYKAYLYSSSTVL*RRMFRNSGGS ISAVVDFG*QITQIGVRQLPISSRKVLII*ENLC LQAPLVPTQPILHPNLNPALPPISKGIATQIMS PMSIPSTKVDHSDSASMDKSLSKLAHADGDQTS IIPVHQVIDKVKGYCNAHSDNFYKNIIMSDTFSH STKF*CL*EKEINLQKCEDLQAV*TATSDVNVL LPR*LHIYKECILLRRLL*NSEFFFLIYFFHGR VVITKTSVLRVT*LSSHRSYDL*NI*LNQSNHNA GETFKLETREKQC*GRP*IELILLHLIVISGYT HFLHLLSQQ*KM*LF*MPTNPIPVLLSVNAVPY SHFQ*HFNHRQKRLFTP*PKD*KGFFIILNITPS EP*HA*ENFPKMLT*LNEAI*ISNILLILFKA* GQSIKYNLIPYIRVKFSVDVPSFWTSQELFKNE SLTPLLLPLYCILSP*ACGRKENFH*ASCMQWNF PFRRHTIKTLWFCPCFGDFKTFPKAQIKASYFP IESFVPRNMK*DIWVSHNNQNNL*RAGSAIASL KTTCVSVLWL*YIRA*GGLAR*MVYYLWIRLLHT NLAYYYAAYLTLRLF*VMLAC**MYRRPHCNCS *MMESMQFLRNRSQCMLCFFTFALGYLGSIRFW EATALSDKKRRHSGKANLLKGKVQNLEPRGLSLC TKNR*FAV*DMGELLGYTATQGTSHLLLSFNQE AICLAPADDEIMR*WVFYYCSILQHPATPSWET RALPSLAFTGEGCIQ*KRIVNIRSLRF*VR**I* GH*AKSFSIGIY*QAAYFGGGYIWMKMNLSH*I FIYISPKTLDIHSRF*LVSFLTSQISAQSA*SI VIKI*LQKWLCF*FLLIFVWLQKNIFFIFDNVSS TLEIFNNQMRKKLRNCSRETFVNGFERLSQILL SVLSMQFSPPFSPPSEQRSGI*LGSLNLVQLTF ENSINSDSLFIMFSFLFPSF*TTLC*SHSLGS*E IFHSCHHSLAL*RFSLSVVGIDSFVHIYLFVFI YVNWFPFLA*YCLALLF*LTFY*RDCIYFF*IL CEIIFGSNIFEYDE*K*L*VQIELAVRSYSS*FA ILLKWKMFFK*ILMLF

Frame 1

QVPRVVAESRLPPAGARTCDAHPCLARSPQHQP HAHPTSSASRPHPANFPARRDLPPACFLVRRPC AERCRAQGSPCAVGKAHELSRNGVKEGPAAAQGW GAWVPPGWSSGSRAGKWWRMILRPKGTSAQ*CQ HDVSLRSNVELPLEMEAQSSPVLICFIYHVCSS LSVGMCQLPSGFVQPFWDLYFSMLP*RLPKQPGL HVDAPSPHRLYHSDNI*RL*H*RSSQLHL*LII P**WREPD*ILWSNCQRPII*LKCE*DACVLFK *L*HPEERFQCQLHQSCRVLKESKGHFTPDIRCL PGICCKKHLYSRAQCFHTLL*SNQSWP*RQ*LD SFLLLKCILHTIAQFWKGQEWLLSIHF*FKMFV E*CITCQRKRRHFCRKL*TALPCLE*FFGLYWCK FQKKL*NSSM*FYH**SYSWEWEIVVGLQSK*N CLSKRGHL*LSTLEFYHECQNPLQPQL*CEREC SRLAK*LLEYPKPSSES*KQPKLWFLPDPAPSSR TGQLCRPGDPLSRWNYL*NIRSDSEHPSSP*GK STEQGGRMAQFNLPKLELHGLCR*YQFSPECWR GQD*SQEKP*G*AKVGALGPSSLQCYQQY*FGRK NHSAEAPKK**VLG*RLEATYSECETTGSLSCH GGTQRLLLAIYPTF*IRSSLSRQAWLFCFSDMF LQCYQPIGNLLGTC*YLQLFKRSK*SC*PDFKFN C*WAELNLSQYYQHCGTGQKNCE*RRKH*YNTW LNSNEYIF*YLKQFRQ*LA*VIF*SFKNN**IG LQDRPK*HITCEYYNSELGSQRIIPVTRDKCNFK F*HWSSKQ**IVFPDGF*EWTSGSTGICNFASK LT*EFKSRRFCIS*KSTVYFLQQNWTFPGCRTP KKNFSELCDGVQYWKHYYPESEGSCSNKNQTYKN SGSASSHLCLLGSEQKQKFWRMEHVRMCCTQRF RCK*DSLPV*PLHTLWSSDGPSKKCLTVRCKKH *SPHFHQLYWVWNICYFFSSNSPDICCF*EIAKG LSLQNLDEPEHSPAVPESPLPPRWLDHLLQCGW TLHCCCSPVAFLPSGNLYLDGARSNSHVHCSS* SI*HLHSPIHSKILHHWLGFACLSGVSCSSEQKQ Q*SLWKRKLWERKR**ILLDSRSSHILCDLCWV FWSHVFSEHCHVHCGNGADLWEEWQEKQPDPER RSVKEPAQCG*LDLSVGHDMGFCILCLGTLKYPL HVPLLHLQFITRLIYIHLPLCYEGECSETVAAA SLLW*ISVSR*LRLE*DSYQYHQEKF**SRKIF VFKLHWFQLNLSYIQI*IQLYHLFQKE*PHR*CL L*AFLQQKWITQTVLPWTSPCQNWPMLMEIKHQ SSLSIRSLIRSRVIAMLIQTTSIKILSCQTPSA TAQSFNVFKKKKSICRNVKICKQCKLQLVM*MCY YLGNCIYIRNVFC*EGFCEIQNFSF*YISSMEE LSSLKLQY*E*HDSVATEAMICKIYN*IRVIIM QGRHSN*RQGRSNAEEDPR*SSFYST*SLYLDIP IFCIFFLNNKKCNYFECPQIPFQCYFL*MQYHI LIFNDISTTGRKDCLLLDPKIKKDFLLF*ILHL QNHNMLKKTFPKC*PS*MRLYKFLIFYLFYSRHR AKALSII*SHTFELSLVLMFHHSGPPRSCLRMN LLHLYFCPSTVY*AHRLVGGRRISIRQAVCSGI FLLGDTQLRLSGSVLALETLRHFLKHK*KPRISP LRVLFQGI*SETYG*VIIIKIIYEELGLQ*LV* KLLVCQSSGYSI*EPEEVWQDRWCIIYGSGCCI QTLHTIMQLT*LSDYSE*CLLANECIGDHIVIVL R*WSPCSFLEIGLSACCAFSHLLWVIWEVSGSG RQQH*VIRKGDILAKPICLKAKSRTWNLEAFLS ARKTGSLQSEIWESF*ATQQPKGPLTFC*ASIRK LFAWLQQMMR**GSGFFITVPFCNILQHHPGRQ EHYPAWLSRGRVVFSKKE**I*GH*DSK*DSKS KVTEPNPFQ*AYINRLLILAEVTYG*K*ILVTEY SYTFPPKP*TFIVDFN*LAF*LVRFLPKVLSQ* *LRYSFKNGFAFDFYSYSYGSRKIFFSYLTMSA PL*KFSITR*EKN*EIAQGKHL*MDLKD*AKFCC QF*ACSSHLHLVPHQNRGQEFSWGA*I*FSLPL RIASIQTLFSLCFLFFFPLFKLHCVRVIV*DPE RFSILVTIHLHCKDFLCLLLA*ILLYIFIYLCLY MSIGFLS*LDIA*LCCFN*LSIRETVYIFSKYF VKSFLVAISLNMMNKSDCECK*N*Q*EATLANL PFYLNGKCFSNKYLCC

Frame 2

KYLGWWPSPASRQRGRGPATRTPAWPGLLSTSP THTLLPQLLALTLPTSLRGGTCRQPASSSAGPA LNAAAPRVHLAPSGKPMNSPETA*RRVPPRRRA GAPGFPLGGAAAAERESGGG*SCGQRGPRRSNVN MMFRSDRMWSCHWKWKPSPLLFLFALYIMCVPH SVWGCANCRVVLSNPSGTFTSPCYPNDYPNSQA CMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS LDNGESQTKFCGATAKGLSFNSSANEMHVSFSS DFSIQKKGFNASYIRVAVSLRNQKVILPQTSDA YQVSVAKSISIPELSAFTLCFEATKVGHEDSDWT AFSYSNASFTQLLSFGKAKSGYFLSISDSKCLL NNALPVKEKEDIFAESFEQLCLVWNNSLGSIGV NFKRNYETVPCDSTISKVIPGNGKLLLGSNQNEI VSLKGDIYNFRLWNFTMNAKILSNLSCNVKGNV VDWQNDFWNIPNLALKAESNLSCGSYLIPLPAA ELASCADLGTLCQDGIIYRISVVIQNILRHPEVK VQSKVAEWLNSTFQNWNYTVYVVNISFHLSAGE DKIKVKRSLEDEPRLVLWALLVYNATNNTNLEG KIIQQKLLKNNESLDEGLRLHTVNVRQLGHCLAM EEPKGYYWPSIQPSEYVLPCPDKPGFSASRICF YNATNPLVTYWGPVDISNCLKEANEVANQILNL TADGQNLTSANITNIVEQVKRIVNKEENIDITLG STLMNIFSNILSSSDSDLLESSSEALKTIDELA FKIDLNSTSHVNITTRNLALSVSSLLPGTNAIS NFSIGLPSNNESYFQMDFESGQVDPLASVILPPN LLENLSPEDSVLVRRAQFTFFNKTGLFQDVGPQ RKTLVSYVMACSIGNITIQNLKDPVQIKIKHTR TQEVHHPICAFWDLNKNKSFGGWNTSGCVAHRDS DASETVCLCNHFTHFGVLMDLPRSASQLDARNT KVLTFISYIGCGISAIFSAATLLTYVAFEKLRR DYPSKILMNLSTALLFLNLLFLLDGWITSFNVDG LCIAVAVLLHFFLLATFTWMGLEAIHMYIALVK VFNTYIRRYILKFCIIGWGLPALVVSVVLASRN NNEVYGKESYGKEKGDEFCWIQDPVIFYVTCAGY FGVMFFLNIAMFIVVMVQICGRNGKRSNRTLRE EVLRNLRSVVSLTFLLGMTWGFAFFAWGPLNIP FMYLFSIFNSLQGLFIFIFHCAMKENVQKQWRQH LCCGRFRLADNSDWSKTATNIIKKSSDNLGKSL SSSSIGSNSTYLTSKSKSSSTTYFKRNSHTDNV SYEHSFNKSGSLRQCFHGQVLVKTGPC*WRSNIN HPCPSGH**GQGLLQCSFRQLL*KYYHVRHLQP QHKVLMSLRKRNQSAEM*RFASSVNCN**CKCA IT*VTAYI*GMYFVKKAFVKFRIFLFNIFLPWKS CHH*NFSTESNMTQ*PQKL*FVKYIIESE*S*C RGDIQIRDKGEAMLRKTLDRAHFTPPNRYIWIY PFSASSFSTIKNVTILNAHKSHSSVTFCECSTIF SFSMTFQPQAEKTVYSLTQRLKRIFYYFKYYTF RTITCLRKLSQNVDLVK*GYINF*YFTYSIQGI GPKH*V*FNPIHSS*V*C*CSIILDLPGVV*E*I SYTSTFAPLLYIKPIGLWEEGEFPLGKLYAVEF SF*ETHN*DSLVLSLLWRL*DIS*STNKSLVFP H*EFCSKEYEVRHMGES**SK*FMKSWVCNS*SK NYLCVSPLVIVYKSLRRSGKIDGVLFMDQAAAY KPCILLCSLPNSQTILSNACLLMNV*ETTL*LF LDDGVHAVS*KSVSVHAVLFHICSGLSGKYQVLG GNSIK**EKETFWQSQSA*RQSPEPGT*RPFSL HEKQVVCSLRYGRAFRLHSNPRDLSPFAELQSG SYLPGSSR**DNEVVGFLLLFHFATSCNTILGDK SITQLGFHGGGLYSVKKNSKYKVTEILSKIVNL RSLSQILFNRHILTGCLFWRRLHMDENES*SLN IHIHFPQNLRHS**ILIS*LSN*SDFCPKCLVNS N*DIASKMALLLISTHIRMAPEKYFFHI*QCQL HFRNFQ*PDEKKIKKLLKGNICKWI*KIEPNSV VSSKHAVLTSI*SPIRTEVRNLAGEPKFSSAYL* E*HQFRLSFHYVFFSFSLFLNYIVLES*SRILR DFPFLSPFTCIVKIFFVCCWHRFFCTYLFICVY ICQLVSFLSLILPSFVVLINFLLERLYIFFLNTL *NHFW*QYL*I**IKVTVSANRISSKKLL*LIC HFT*MENVFQINTYVV

Sequence NM_020455

CCAAGTACCTAGGGTGGTGGCCGAGTCCCGCCTCCCGCCAGCGGGGGCGAGGACCTGCGACGCGCACCCCTGCCTGGCCCGGTCTCCTCAGCACCAGCCC CACGCACACCCTACTTCCTCAGCTTCTCGCCCTCACCCTGCCAACTTCCCTGCGAGGAGGGACCTGCCGCCAGCCTGCTTCCTCGTCCGCAGGCCCTGCG CTGAACGCTGCCGCGCCCAGGGTTCACCTTGCGCCGTCGGGAAAGCCCATGAACTCTCCAGAAACGGCGTAAAGGAGGGTCCCGCCGCGGCGCAGGGCTG GGGCGCCTGGGTTCCCCCTGGGTGGAGCAGCGGCAGCAGAGCGGGAAAGTGGTGGAGGATGATCTTGCGGCCAAAGGGGACCTCGGCGCAGTAATGTCAA CATGATGTTTCGCTCAGATCGAATGTGGAGCTGCCATTGGAAATGGAAGCCCAGTCCTCTCCTGTTCTTATTTGCTTTATATATCATGTGTGTTCCTCAC TCAGTGTGGGGATGTGCCAACTGCCGAGTGGTTTTGTCCAACCCTTCTGGGACCTTTACTTCTCCATGCTACCCTAACGACTACCCAAACAGCCAGGCTT GCATGTGGACGCTCCGAGCCCCCACCGGTTATATCATTCAGATAACATTTAACGACTTTGACATTGAAGAAGCTCCCAATTGCATTTATGACTCATTATC CCTTGATAATGGAGAGAGCCAGACTAAATTTTGTGGAGCAACTGCCAAAGGCCTATCATTTAACTCAAGTGCGAATGAGATGCATGTGTCCTTTTCAAGT GACTTTAGCATCCAGAAGAAAGGTTTCAATGCCAGCTACATCAGAGTTGCCGTGTCCTTAAGGAATCAAAAGGTCATTTTACCCCAGACATCAGATGCTT ACCAGGTATCTGTTGCAAAAAGCATCTCTATTCCAGAGCTCAGTGCTTTCACACTCTGCTTTGAAGCAACCAAAGTTGGCCATGAAGACAGTGATTGGAC AGCTTTCTCCTACTCAAATGCATCCTTCACACAATTGCTCAGTTTTGGAAAGGCCAAGAGTGGCTACTTTCTATCCATTTCTGATTCAAAATGTTTGTTG AATAATGCATTACCTGTCAAAGAAAAAGAAGACATTTTTGCAGAAAGCTTTGAACAGCTCTGCCTTGTTTGGAATAATTCTTTGGGCTCTATTGGTGTAA ATTTCAAAAGAAACTATGAAACAGTTCCATGTGATTCTACCATTAGTAAAGTTATTCCTGGGAATGGGAAATTGTTGTTGGGCTCCAATCAAAATGAAAT TGTCTCTCTAAAAGGGGACATTTATAACTTTCGACTTTGGAATTTTACCATGAATGCCAAAATCCTCTCCAACCTCAGCTGTAATGTGAAAGGGAATGTA GTCGACTGGCAAAATGACTTCTGGAATATCCCAAACCTAGCTCTGAAAGCTGAAAGCAACCTAAGCTGTGGTTCCTACCTGATCCCGCTCCCAGCAGCAG AACTGGCCAGCTGTGCAGACCTGGGGACCCTCTGTCAAGCTACTGTAAACTCTCCTAGTACTACACCACCCACTGTCACCACTAACATGCCTGTTACTAA CAGAATCGATAAACAAAGGAATGATGGAATTATCTATAGAATATCCGTAGTGATTCAGAACATCCTTCGTCACCCTGAGGTAAAAGTACAGAGCAAGGTG GCAGAATGGCTCAATTCAACCTTCCAAAATTGGAACTACACGGTTTATGTCGTTAATATCAGTTTTCACCTGAGTGCTGGAGAGGACAAGATTAAAGTCA AGAGAAGCCTTGAGGATGAGCCAAGGTTGGTGCTTTGGGCCCTTCTAGTTTACAATGCTACCAACAATACTAATTTGGAAGGAAAAATCATTCAGCAGAA GCTCCTAAAAAATAATGAGTCCTTGGATGAAGGCTTGAGGCTACATACAGTGAATGTGAGACAACTGGGTCATTGTCTTGCCATGGAGGAACCCAAAGGC TACTACTGGCCATCTATCCAACCTTCTGAATACGTTCTTCCTTGTCCAGACAAGCCTGGCTTTTCTGCTTCTCGGATATGTTTTTACAATGCTACCAACC CATTGGTAACCTACTGGGGACCTGTTGATATCTCCAACTGTTTAAAAGAAGCAAATGAAGTTGCTAACCAGATTTTAAATTTAACTGCTGATGGGCAGAA CTTAACCTCAGCCAATATTACCAACATTGTGGAACAGGTCAAAAGAATTGTGAATAAAGAAGAAAACATTGATATAACACTTGGCTCAACTCTAATGAAT ATATTTTCTAATATCTTAAGCAGTTCAGACAGTGACTTGCTTGAGTCATCTTCTGAAGCTTTAAAAACAATTGATGAATTGGCCTTCAAGATAGACCTAA ATAGCACATCACATGTGAATATTACAACTCGGAACTTGGCTCTCAGCGTATCATCCCTGTTACCAGGGACAAATGCAATTTCAAATTTTAGCATTGGTCT TCCAAGCAATAATGAATCGTATTTCCAGATGGATTTTGAGAGTGGACAAGTGGATCCACTGGCATCTGTAATTTTGCCTCCAAACTTACTTGAGAATTTA AGTCCAGAAGATTCTGTATTAGTTAGAAGAGCACAGTTTACTTTCTTCAACAAAACTGGACTTTTCCAGGATGTAGGACCCCAAAGAAAAACTTTAGTGA GTTATGTGATGGCGTGCAGTATTGGAAACATTACTATCCAGAATCTGAAGGATCCTGTTCAAATAAAAATCAAACATACAAGAACTCAGGAAGTGCATCA TCCCATCTGTGCCTTCTGGGATCTGAACAAAAACAAAAGTTTTGGAGGATGGAACACGTCAGGATGTGTTGCACACAGAGATTCAGATGCAAGTGAGACA GTCTGCCTGTGTAACCACTTCACACACTTTGGAGTTCTGATGGACCTTCCAAGAAGTGCCTCACAGTTAGATGCAAGAAACACTAAAGTCCTCACTTTCA TCAGCTATATTGGGTGTGGAATATCTGCTATTTTTTCAGCAGCAACTCTCCTGACATATGTTGCTTTTGAGAAATTGCGAAGGGATTATCCCTCCAAAAT CTTGATGAACCTGAGCACAGCCCTGCTGTTCCTGAATCTCCTCTTCCTCCTAGATGGCTGGATCACCTCCTTCAATGTGGATGGACTTTGCATTGCTGTT GCAGTCCTGTTGCATTTCTTCCTTCTGGCAACCTTTACCTGGATGGGGCTAGAAGCAATTCACATGTACATTGCTCTAGTTAAAGTATTTAACACTTACA TTCGCCGATACATTCTAAAATTCTGCATCATTGGCTGGGGTTTGCCTGCCTTAGTGGTGTCAGTTGTTCTAGCGAGCAGAAACAACAATGAAGTCTATGG AAAAGAAAGTTATGGGAAAGAAAAAGGTGATGAATTCTGTTGGATTCAAGATCCAGTCATATTTTATGTGACCTGTGCTGGGTATTTTGGAGTCATGTTT TTTCTGAACATTGCCATGTTCATTGTGGTAATGGTGCAGATCTGTGGGAGGAATGGCAAGAGAAGCAACCGGACCCTGAGAGAAGAAGTGTTAAGGAACC TGCGCAGTGTGGTTAGCTTGACCTTTCTGTTGGGCATGACATGGGGTTTTGCATTCTTTGCCTGGGGACCCTTAAATATCCCCTTCATGTACCTCTTCTC CATCTTCAATTCATTACAAGGCTTATTTATATTCATCTTCCACTGTGCTATGAAGGAGAATGTTCAGAAACAGTGGCGGCAGCATCTCTGCTGTGGTAGA TTTCGGTTAGCAGATAACTCAGATTGGAGTAAGACAGCTACCAATATCATCAAGAAAAGTTCTGATAATCTAGGAAAATCTTTGTCTTCAAGCTCCATTG GTTCCAACTCAACCTATCTTACATCCAAATCTAAATCCAGCTCTACCACCTATTTCAAAAGGAATAGCCACACAGATAATGTCTCCTATGAGCATTCCTT CAACAAAAGTGGATCACTCAGACAGTGCTTCCATGGACAAGTCCTTGTCAAAACTGGCCCATGCTGATGGAGATCAAACATCAATCATCCCTGTCCATCA GGTCATTGATAAGGTCAAGGGTTATTGCAATGCTCATTCAGACAACTTCTATAAAAATATTATCATGTCAGACACCTTCAGCCACAGCACAAAGTTTTAA TGTCTTTAAGAAAAAGAAATCAATCTGCAGAAATGTGAAGATTTGCAAGCAGTGTAAACTGCAACTAGTGATGTAAATGTGCTATTACCTAGGTAACTGC ATATATATAAGGAATGTATTTTGTTAAGAAGGCTTTTGTGAAATTCAGAATTTTTCTTTTTAATATATTTCTTCCATGGAAGAGTTGTCATCACTAAAAC TTCAGTACTGAGAGTAACATGACTCAGTAGCCACAGAAGCTATGATTTGTAAAATATATAATTGAATCAGAGTAATCATAATGCAGGGGAGACATTCAAA TTAGAGACAAGGGAGAAGCAATGCTGAGGAAGACCCTAGATAGAGCTCATTTTACTCCACCTAATCGTTATATCTGGATATACCCATTTTCTGCATCTTC TTTCTCAACAATAAAAAATGTAACTATTTTGAATGCCCACAAATCCCATTCCAGTGTTACTTTCTGTGAATGCAGTACCATATTCTCATTTTCAATGACA TTTCAACCACAGGCAGAAAAGACTGTTTACTCCTTGACCCAAAGATTAAAAAGGATTTTTTATTATTTTAAATATTACACCTTCAGAACCATAACATGCT TAAGAAAACTTTCCCAAAATGTTGACCTAGTTAAATGAGGCTATATAAATTTCTAATATTTTACTTATTCTATTCAAGGCATAGGGCCAAAGCATTAAGT ATAATTTAATCCCATACATTCGAGTTAAGTTTAGTGTTGATGTTCCATCATTCTGGACCTCCCAGGAGTTGTTTAAGAATGAATCTCTTACACCTCTACT TTTGCCCCTCTACTGTATATTAAGCCCATAGGCTTGTGGGAGGAAGGAGAATTTCCATTAGGCAAGCTGTATGCAGTGGAATTTTCCTTTTAGGAGACAC ACAATTAAGACTCTCTGGTTCTGTCCTTGCTTTGGAGACTTTAAGACATTTCCTAAAGCACAAATAAAAGCCTCGTATTTCCCCATTGAGAGTTTTGTTC CAAGGAATATGAAGTGAGACATATGGGTGAGTCATAATAATCAAAATAATTTATGAAGAGCTGGGTCTGCAATAGCTAGTCTAAAAACTACTTGTGTGTC AGTCCTCTGGTTATAGTATATAAGAGCCTGAGGAGGTCTGGCAAGATAGATGGTGTATTATTTATGGATCAGGCTGCTGCATACAAACCTTGCATACTAT TATGCAGCTTACCTAACTCTCAGACTATTCTGAGTAATGCTTGCTTGCTAATGAATGTATAGGAGACCACATTGTAATTGTTCTTAGATGATGGAGTCCA TGCAGTTTCTTAGAAATCGGTCTCAGTGCATGCTGTGCTTTTTCACATTTGCTCTGGGTTATCTGGGAAGTATCAGGTTCTGGGAGGCAACAGCATTAAG TGATAAGAAAAGGAGACATTCTGGCAAAGCCAATCTGCTTAAAGGCAAAGTCCAGAACCTGGAACCTAGAGGCCTTTCTCTCTGCACGAAAAACAGGTAG TTTGCAGTCTGAGATATGGGAGAGCTTTTAGGCTACACAGCAACCCAAGGGACCTCTCACCTTTTGCTGAGCTTCAATCAGGAAGCTATTTGCCTGGCTC CAGCAGATGATGAGATAATGAGGTAGTGGGTTTTTTATTACTGTTCCATTTTGCAACATCCTGCAACACCATCCTGGGAGACAAGAGCATTACCCAGCTT GGCTTTCACGGGGGAGGGTTGTATTCAGTAAAAAAGAATAGTAAATATAAGGTCACTGAGATTCTAAGTAAGATAGTAAATCTAAGGTCACTGAGCCAAA TCCTTTTCAATAGGCATATATTAACAGGCTGCTTATTTTGGCGGAGGTTACATATGGATGAAAATGAATCTTAGTCACTGAATATTCATATACATTTCCC CCAAAACCTTAGACATTCATAGTAGATTTTAATTAGTTAGCTTTCTAACTAGTCAGATTTCTGCCCAAAGTGCTTAGTCAATAGTAATTAAGATATAGCT TCAAAAATGGCTTTGCTTTTGATTTCTACTCATATTCGTATGGCTCCAGAAAAATATTTTTTTCATATTTGACAATGTCAGCTCCACTTTAGAAATTTTC AATAACCAGATGAGAAAAAAATTAAGAAATTGCTCAAGGGAAACATTTGTAAATGGATTTGAAAGATTGAGCCAAATTCTGTTGTCAGTTCTAAGCATGC AGTTCTCACCTCCATTTAGTCCCCCATCAGAACAGAGGTCAGGAATTTAGCTGGGGAGCCTAAATTTAGTTCAGCTTACCTTTGAGAATAGCATCAATTC AGACTCTCTTTTCATTATGTTTTCTTTTCTTTTTCCCTCTTTTTAAACTACATTGTGTTAGAGTCATAGTCTAGGATCCTGAGAGATTTTCCATTCTTGT CACCATTCACTTGCATTGTAAAGATTTTCTTTGTCTGTTGTTGGCATAGATTCTTTTGTACATATTTATTTATTTGTGTTTATATATGTCAATTGGTTTC CTTTCTTAGCTTGATATTGCCTAGCTTTGTTGTTTTAATTAACTTTCTATTAGAGAGACTGTATATATTTTTTCTAAATACTTTGTGAAATCATTTTTGG TAGCAATATCTTTGAATATGATGAATAAAAGTGACTGTGAGTGCAAATAGAATTAGCAGTAAGAAGCTACTCTAGCTAATTTGCCATTTTACTTAAATGG AAAATGTTTTTCAAATAAATACTTATGTTGTTC

refseq_GPR126.F3 (forward primer)
refseq_GPR126.R3 (reverse primer)
Single exon skipping

Frame 0

PST*GGGRVPPPASGGEDLRRAPLPGPVSSAPA PRTPYFLSFSPSPCQLPCEEGPAASLLPRPQALR *TLPRPGFTLRRRESP*TLQKRRKGGSRRGAGL GRLGSPWVEQRQQSGKVVEDDLAAKGDLGAVMS T*CFAQIECGAAIGNGSPVLSCSYLLYISCVFLT QCGDVPTAEWFCPTLLGPLLLHATLTTTQTARL ACGRSEPPPVISFR*HLTTLTLKKLPIAFMTHY PLIMERARLNFVEQLPKAYHLTQVRMRCMCPFQV TLASRRKVSMPATSELPCP*GIKRSFYPRHQML TRYLLQKASLFQSSVLSHSALKQPKLAMKTVIG QLSPTQMHPSHNCSVLERPRVATFYPFLIQNVC* IMHYLSKKKKTFLQKALNSSALFGIILWALLV* ISKETMKQFHVILPLVKLFLGMGNCCWAPIKMK LSL*KGTFITFDFGILP*MPKSSPTSAVM*KGM* STGKMTSGISQT*L*KLKAT*AVVPT*SRSQQQ NWPAVQTWGPSVKLL*TLLVLHHPLSPLTCLLL TESINKGMMELSIEYP**FRTSFVTLR*KYRARW QNGSIQPSKIGTTRFMSLISVFT*VLERTRLKS REALRMSQGWCFGPF*FTMLPTILIWKEKSFSR SS*KIMSPWMKA*GYIQ*M*DNWVIVLPWRNPKA TTGHLSNLLNTFFLVQTSLAFLLLGYVFTMLPT HW*PTGDLLISPTV*KKQMKLLTRF*I*LLMGR T*PQPILPTLWNRSKEL*IKKKTLI*HLAQL**I YFLIS*AVQTVTCLSHLLKL*KQLMNWPSR*T* IAHHM*ILQLGTWLSAYHPCYQGQMQFQILALV FQAIMNRISRWILRVDKWIHWHL*FCLQTYLRI* VQKILY*LEEHSLLSSTKLDFSRM*DPKEKL** VM*WRAVLETLLSRI*RILFK*KSNIQELRKCI IPSVPSGI*TKTKVLEDGTRQDVLHTEIQMQVRQ SACVTTSHTLEF*WTFQEVPHS*MQETLKSSLS SAILGVEYLLFFQQQLS*HMLLLRNCEGIIPPK S**T*AQPCCS*ISSSS*MAGSPPSMWMDFALLL QSCCISSFWQPLPGWG*KQFTCTLL*LKYLTLT FADTF*NSASLAGVCLP*WCQLF*RAETTMKSM EKKVMGKKKVMNSVGFKIQSYFM*PVLGILESCF F*TLPCSLW*WCRSVGGMAREATGP*EKKC*GT CAVWLA*PFCWA*HGVLHSLPGDP*ISPSCTSS PSSIHYKAYLYSSSTVL*RRMFRNSGGSISAVVD FG*QITQIGVRQLPISSRKVLII*ENLCLQAPL VPTQPILHPNLNPALPPISKGIATQIMSPMSIP STKVDHSDSASMDKSLSKLAHADGDQTSIIPVHQ VIDKVKGYCNAHSDNFYKNIIMSDTFSHSTKF* CL*EKEINLQKCEDLQAV*TATSDVNVLLPR*L HIYKECILLRRLL*NSEFFFLIYFFHGRVVITKT SVLRVT*LSSHRSYDL*NI*LNQSNHNAGETFK LETREKQC*GRP*IELILLHLIVISGYTHFLHL LSQQ*KM*LF*MPTNPIPVLLSVNAVPYSHFQ*H FNHRQKRLFTP*PKD*KGFFIILNITPSEP*HA *ENFPKMLT*LNEAI*ISNILLILFKA*GQSIK YNLIPYIRVKFSVDVPSFWTSQELFKNESLTPLL LPLYCILSP*ACGRKENFH*ASCMQWNFPFRRH TIKTLWFCPCFGDFKTFPKAQIKASYFPIESFV PRNMK*DIWVSHNNQNNL*RAGSAIASLKTTCVS VLWL*YIRA*GGLAR*MVYYLWIRLLHTNLAYY YAAYLTLRLF*VMLAC**MYRRPHCNCS*MMES MQFLRNRSQCMLCFFTFALGYLGSIRFWEATALS DKKRRHSGKANLLKGKVQNLEPRGLSLCTKNR* FAV*DMGELLGYTATQGTSHLLLSFNQEAICLA PADDEIMR*WVFYYCSILQHPATPSWETRALPSL AFTGEGCIQ*KRIVNIRSLRF*VR**I*GH*AK SFSIGIY*QAAYFGGGYIWMKMNLSH*IFIYIS PKTLDIHSRF*LVSFLTSQISAQSA*SIVIKI*L QKWLCF*FLLIFVWLQKNIFFIFDNVSSTLEIF NNQMRKKLRNCSRETFVNGFERLSQILLSVLSM QFSPPFSPPSEQRSGI*LGSLNLVQLTFENSINS DSLFIMFSFLFPSF*TTLC*SHSLGS*EIFHSC HHSLAL*RFSLSVVGIDSFVHIYLFVFIYVNWF PFLA*YCLALLF*LTFY*RDCIYFF*ILCEIIFG SNIFEYDE*K*L*VQIELAVRSYSS*FAILLKW KMFFK*ILMLF

Frame 1

QVPRVVAESRLPPAGARTCDAHPCLARSPQHQP HAHPTSSASRPHPANFPARRDLPPACFLVRRPC AERCRAQGSPCAVGKAHELSRNGVKEGPAAAQGW GAWVPPGWSSGSRAGKWWRMILRPKGTSAQ*CQ HDVSLRSNVELPLEMEAQSSPVLICFIYHVCSS LSVGMCQLPSGFVQPFWDLYFSMLP*RLPKQPGL HVDAPSPHRLYHSDNI*RL*H*RSSQLHL*LII P**WREPD*ILWSNCQRPII*LKCE*DACVLFK *L*HPEERFQCQLHQSCRVLKESKGHFTPDIRCL PGICCKKHLYSRAQCFHTLL*SNQSWP*RQ*LD SFLLLKCILHTIAQFWKGQEWLLSIHF*FKMFV E*CITCQRKRRHFCRKL*TALPCLE*FFGLYWCK FQKKL*NSSM*FYH**SYSWEWEIVVGLQSK*N CLSKRGHL*LSTLEFYHECQNPLQPQL*CEREC SRLAK*LLEYPKPSSES*KQPKLWFLPDPAPSSR TGQLCRPGDPLSSYCKLS*YYTTHCHH*HACY* QNR*TKE*WNYL*NIRSDSEHPSSP*GKSTEQG GRMAQFNLPKLELHGLCR*YQFSPECWRGQD*SQ EKP*G*AKVGALGPSSLQCYQQY*FGRKNHSAE APKK**VLG*RLEATYSECETTGSLSCHGGTQR LLLAIYPTF*IRSSLSRQAWLFCFSDMFLQCYQP IGNLLGTC*YLQLFKRSK*SC*PDFKFNC*WAE LNLSQYYQHCGTGQKNCE*RRKH*YNTWLNSNE YIF*YLKQFRQ*LA*VIF*SFKNN**IGLQDRPK *HITCEYYNSELGSQRIIPVTRDKCNFKF*HWS SKQ**IVFPDGF*EWTSGSTGICNFASKLT*EF KSRRFCIS*KSTVYFLQQNWTFPGCRTPKKNFSE LCDGVQYWKHYYPESEGSCSNKNQTYKNSGSAS SHLCLLGSEQKQKFWRMEHVRMCCTQRFRCK*D SLPV*PLHTLWSSDGPSKKCLTVRCKKH*SPHFH QLYWVWNICYFFSSNSPDICCF*EIAKGLSLQN LDEPEHSPAVPESPLPPRWLDHLLQCGWTLHCC CSPVAFLPSGNLYLDGARSNSHVHCSS*SI*HLH SPIHSKILHHWLGFACLSGVSCSSEQKQQ*SLW KRKLWERKR**ILLDSRSSHILCDLCWVFWSHV FSEHCHVHCGNGADLWEEWQEKQPDPERRSVKEP AQCG*LDLSVGHDMGFCILCLGTLKYPLHVPLL HLQFITRLIYIHLPLCYEGECSETVAAASLLW* ISVSR*LRLE*DSYQYHQEKF**SRKIFVFKLHW FQLNLSYIQI*IQLYHLFQKE*PHR*CLL*AFL QQKWITQTVLPWTSPCQNWPMLMEIKHQSSLSI RSLIRSRVIAMLIQTTSIKILSCQTPSATAQSFN VFKKKKSICRNVKICKQCKLQLVM*MCYYLGNC IYIRNVFC*EGFCEIQNFSF*YISSMEELSSLK LQY*E*HDSVATEAMICKIYN*IRVIIMQGRHSN *RQGRSNAEEDPR*SSFYST*SLYLDIPIFCIF FLNNKKCNYFECPQIPFQCYFL*MQYHILIFND ISTTGRKDCLLLDPKIKKDFLLF*ILHLQNHNML KKTFPKC*PS*MRLYKFLIFYLFYSRHRAKALS II*SHTFELSLVLMFHHSGPPRSCLRMNLLHLY FCPSTVY*AHRLVGGRRISIRQAVCSGIFLLGDT QLRLSGSVLALETLRHFLKHK*KPRISPLRVLF QGI*SETYG*VIIIKIIYEELGLQ*LV*KLLVC QSSGYSI*EPEEVWQDRWCIIYGSGCCIQTLHTI MQLT*LSDYSE*CLLANECIGDHIVIVLR*WSP CSFLEIGLSACCAFSHLLWVIWEVSGSGRQQH* VIRKGDILAKPICLKAKSRTWNLEAFLSARKTGS LQSEIWESF*ATQQPKGPLTFC*ASIRKLFAWL QQMMR**GSGFFITVPFCNILQHHPGRQEHYPA WLSRGRVVFSKKE**I*GH*DSK*DSKSKVTEPN PFQ*AYINRLLILAEVTYG*K*ILVTEYSYTFP PKP*TFIVDFN*LAF*LVRFLPKVLSQ**LRYS FKNGFAFDFYSYSYGSRKIFFSYLTMSAPL*KFS ITR*EKN*EIAQGKHL*MDLKD*AKFCCQF*AC SSHLHLVPHQNRGQEFSWGA*I*FSLPLRIASI QTLFSLCFLFFFPLFKLHCVRVIV*DPERFSILV TIHLHCKDFLCLLLA*ILLYIFIYLCLYMSIGF LS*LDIA*LCCFN*LSIRETVYIFSKYFVKSFL VAISLNMMNKSDCECK*N*Q*EATLANLPFYLNG KCFSNKYLCC

Frame 2

KYLGWWPSPASRQRGRGPATRTPAWPGLLSTSP THTLLPQLLALTLPTSLRGGTCRQPASSSAGPA LNAAAPRVHLAPSGKPMNSPETA*RRVPPRRRA GAPGFPLGGAAAAERESGGG*SCGQRGPRRSNVN MMFRSDRMWSCHWKWKPSPLLFLFALYIMCVPH SVWGCANCRVVLSNPSGTFTSPCYPNDYPNSQA CMWTLRAPTGYIIQITFNDFDIEEAPNCIYDSLS LDNGESQTKFCGATAKGLSFNSSANEMHVSFSS DFSIQKKGFNASYIRVAVSLRNQKVILPQTSDA YQVSVAKSISIPELSAFTLCFEATKVGHEDSDWT AFSYSNASFTQLLSFGKAKSGYFLSISDSKCLL NNALPVKEKEDIFAESFEQLCLVWNNSLGSIGV NFKRNYETVPCDSTISKVIPGNGKLLLGSNQNEI VSLKGDIYNFRLWNFTMNAKILSNLSCNVKGNV VDWQNDFWNIPNLALKAESNLSCGSYLIPLPAA ELASCADLGTLCQATVNSPSTTPPTVTTNMPVTN RIDKQRNDGIIYRISVVIQNILRHPEVKVQSKV AEWLNSTFQNWNYTVYVVNISFHLSAGEDKIKV KRSLEDEPRLVLWALLVYNATNNTNLEGKIIQQK LLKNNESLDEGLRLHTVNVRQLGHCLAMEEPKG YYWPSIQPSEYVLPCPDKPGFSASRICFYNATN PLVTYWGPVDISNCLKEANEVANQILNLTADGQN LTSANITNIVEQVKRIVNKEENIDITLGSTLMN IFSNILSSSDSDLLESSSEALKTIDELAFKIDL NSTSHVNITTRNLALSVSSLLPGTNAISNFSIGL PSNNESYFQMDFESGQVDPLASVILPPNLLENL SPEDSVLVRRAQFTFFNKTGLFQDVGPQRKTLV SYVMACSIGNITIQNLKDPVQIKIKHTRTQEVHH PICAFWDLNKNKSFGGWNTSGCVAHRDSDASET VCLCNHFTHFGVLMDLPRSASQLDARNTKVLTF ISYIGCGISAIFSAATLLTYVAFEKLRRDYPSKI LMNLSTALLFLNLLFLLDGWITSFNVDGLCIAV AVLLHFFLLATFTWMGLEAIHMYIALVKVFNTY IRRYILKFCIIGWGLPALVVSVVLASRNNNEVYG KESYGKEKGDEFCWIQDPVIFYVTCAGYFGVMF FLNIAMFIVVMVQICGRNGKRSNRTLREEVLRN LRSVVSLTFLLGMTWGFAFFAWGPLNIPFMYLFS IFNSLQGLFIFIFHCAMKENVQKQWRQHLCCGR FRLADNSDWSKTATNIIKKSSDNLGKSLSSSSI GSNSTYLTSKSKSSSTTYFKRNSHTDNVSYEHSF NKSGSLRQCFHGQVLVKTGPC*WRSNINHPCPS GH**GQGLLQCSFRQLL*KYYHVRHLQPQHKVL MSLRKRNQSAEM*RFASSVNCN**CKCAIT*VTA YI*GMYFVKKAFVKFRIFLFNIFLPWKSCHH*N FSTESNMTQ*PQKL*FVKYIIESE*S*CRGDIQ IRDKGEAMLRKTLDRAHFTPPNRYIWIYPFSASS FSTIKNVTILNAHKSHSSVTFCECSTIFSFSMT FQPQAEKTVYSLTQRLKRIFYYFKYYTFRTITC LRKLSQNVDLVK*GYINF*YFTYSIQGIGPKH*V *FNPIHSS*V*C*CSIILDLPGVV*E*ISYTST FAPLLYIKPIGLWEEGEFPLGKLYAVEFSF*ET HN*DSLVLSLLWRL*DIS*STNKSLVFPH*EFCS KEYEVRHMGES**SK*FMKSWVCNS*SKNYLCV SPLVIVYKSLRRSGKIDGVLFMDQAAAYKPCIL LCSLPNSQTILSNACLLMNV*ETTL*LFLDDGVH AVS*KSVSVHAVLFHICSGLSGKYQVLGGNSIK **EKETFWQSQSA*RQSPEPGT*RPFSLHEKQV VCSLRYGRAFRLHSNPRDLSPFAELQSGSYLPGS SR**DNEVVGFLLLFHFATSCNTILGDKSITQL GFHGGGLYSVKKNSKYKVTEILSKIVNLRSLSQ ILFNRHILTGCLFWRRLHMDENES*SLNIHIHFP QNLRHS**ILIS*LSN*SDFCPKCLVNSN*DIA SKMALLLISTHIRMAPEKYFFHI*QCQLHFRNF Q*PDEKKIKKLLKGNICKWI*KIEPNSVVSSKHA VLTSI*SPIRTEVRNLAGEPKFSSAYL*E*HQF RLSFHYVFFSFSLFLNYIVLES*SRILRDFPFL SPFTCIVKIFFVCCWHRFFCTYLFICVYICQLVS FLSLILPSFVVLINFLLERLYIFFLNTL*NHFW *QYL*I**IKVTVSANRISSKKLL*LICHFT*M ENVFQINTYVV