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Sequences

Sequence NM_177422

ACTTCCGGACGGGACTCCCCTCTGTCCGCGCCTCACATCTCCCCTTCCTCTCGCCTAGTCCTGTGCCGTTTTCCGTCCGCGACTCTTCCGGCCCAGAGCT
TTCGGAGTGCGGTTGCTCAGGGGAAGCCGTCGCCGCCCCCGCCTCGGGGCCGAGTGAGAGTGCCCGTCGCGTCGCGCCGCGTCGCCCCCCGGGCCGCCTC
CTTGCCGCCAGTGGCGGGCTCCGTTCTCCCTCGAAGCACTCCCCCCAGCTCCATGAATGGAAATCGGCTCCGCAGGACCCGCTGGGGCCCAGCCCCTACT
CATGGTGCCCAGAAGACCTGGCTATGGCACCATGGGCAAACCCATTAAACTGCTGGCTAACTGTTTTCAAGTTGAAATCCCAAAGATTGATGTCTACCTC
TATGAGGTAGATATTAAACCAGACAAGTGTCCTAGGAGAGTGAACAGGTAGATTTAGACGTTACTTTACCTGGGGAAGGTGGAAAAGATCGACCTTTCAA
GGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCACTGGAATTAGACAAGCCAATC
AGCACTAACC
CTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAATTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTC
ATGTGTGAAGTTCTTGATATTCATAATATTGATGAGCAACCAAGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGG
TTGAAGTGACTCATTGTGGAACAATGAGACGGAAATACCGTGTTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAA
CGGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGAAAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAAGTCGGGCAGGAA
CAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTGGCAGGGCAACGATGTATCAAGAAGCTAACAGACAATCAGACTTCCACTATGATCAAGG
CAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCAGATTGGTAAGAAGTGCAAATTATGAAACAGATCCATTTGTTCAGGAGTTTCAATTTAA
AGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCCAGCACCTATGCTCCAGTATGGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGA
GTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAAATCAAAATGTGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATAT
TGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGATGCAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAG
CGTAGAGCCCATGTTCCGGCATCTCAAGAACACATATTCTGGCCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAA
CGTGTAGGAGACACACTTTTGGGTATGGCTACACAATGTGTTCAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGA
TAAATGTTAAACTCGGAGGGATCAATAATATTCTTGTACCTCATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCA
TCCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGTTGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAGAGTTCAGAGA
CCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGGGAACTTCTTATTCAATTTTATAAGTCAACTCGGTTCAAGCCTACTCGTATCATCTTTT
ATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTATATTATGAACTACTAGCAATTCGAGAAGCCTGCATCAGTTTGGAGAAAGACTATCAACC
TGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCGATTATTTTGTGCTGATAGGACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGA
ACAACAGTTGATACAGACATTACACACCCATATGAGTTCGATTTTTACCTCTGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATG
TTTTATGGGATGATAACTGCTTTACTGCAGATGAACTTCAGCTGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACC
TGCACCAGCGTATTATGCTCACCTGGTAGCATTTAGAGCCAGATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAA
AGCAATGGGCGAGATCCACAAGCTCTTGCCAAGGCTGTACAGATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGTCCAAGTATATTCTC
TGAGAGGAAGTACTGAAAGATGAATTGACATACAACGTATGTTTCCAGTGAAGTCAATTGAGTAAGGACACCTCCAGCCATACAGAAACCAACACTGTGT
GGGGGCCAAGGTCTGATCCTTATGTTAATACAAGGAAGATTGTTTACTTCATCAAGGAACACAGCATCATTATGCAATATGAAACCAGCCAACTGCTTTT
TGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTCATTTCTTGTAGTCTAACCCTTTTAATGCCTTTACCTCAAGTTGCTTGGCAGCACAACT
ATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTAAAAAATACACACCTTCATGAATAATCAAAGTGATTTTTCAGAATTATGTGTGCAAAAA
ATTAATGTGCATTCATATATTCTTGTAAAAGGTGTCTGTGTATTTTTAAAATATATACATCCATACTTCATATGCATATATATCTAGATCTGGATTGATA
ATAGATATATATGTGTCTGTTATATATTTTAGAGTTCATTCCATTGGGGAATTTTCTTTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATT
TCCCTTGCCTTCATCACCTACATTTTTTTCCCAGTCCTACCAGTGACATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTA
  • refseq_EIF2C3.F4 (forward primer)
  • refseq_EIF2C3.R4 (reverse primer)
  • Single exon skipping

Frame 0

TSGRDSPLSAPHISPSSRLVLCRFPSATLPAQS
FRSAVAQGKPSPPPPRGRVRVPVASRRVAPRAAS
LPPVAGSVLPRSTPPSSMNGNRLRRTRWGPAPT
HGAQKTWLWHHGQTH*TAG*LFSS*NPKD*CLP
L*GRY*TRQVS*ESEQVDLDVTLPGEGGKDRPFK
VSIKFVSRVSWHLLHEVLTGRTLPEPLELDKPI
STN
PVHAVDVVLRHLPSMNFCHCLLQSTTCNSV
HV*SS*YS*Y**ATKTSD*FSSGKIHQRDKRFEG
*SDSLWNNETEIPCL*CNKEACQSSNLSFTVRK
RPNCGENSSAVFQRKVYSSAEVPAPSLSASRAG
TETHLPATRSL*YCGRATMYQEANRQSDFHYDQG
NSKICTR*TRGN*QIGKKCKL*NRSICSGVSI*
SSG*NGSCNWTRTSSTYAPVWRTESDSSNTEPW
SMGHARETIPHRS*NQNVGYRLFCHTEAVQRRNI
EGFHRPAA*DF*GCRDAHPGPAMLLQICTGGRQ
RRAHVPASQEHIFWPTAYYRHPAGEDTSVCGSE
TCRRHTFGYGYTMCSSQECNKNISSNSVKLVPKD
KC*TRRDQ*YSCTSSKTFCVPATSDLFGSRCHS
STCW*WKEAFYCCCCR*YGCTPKQILCHSKSSE
TPTGDHPGLGLHGPGTSYSIL*VNSVQAYSYHLL
SGWCFRGAV*AGIIL*TTSNSRSLHQFGERLST
WNNLHCSSEETSHSIILC**DRKGWKKWQYPSW
NNS*YRHYTPI*VRFLPL*PCWNTGYQSSFTLSC
FMG**LLYCR*TSAANLPALPHLRTLYTICFYT
CTSVLCSPGSI*SQISSCGQRT*QC*RKSRFRT
KQWARSTSSCQGCTDSPRYLTHNVLRLNSPSIFS
ERKY*KMN*HTTYVSSEVN*VRTPPAIQKPTLC
GGQGLILMLIQGRLFTSSRNTASLCNMKPANCF
LCGLL*EVSQLFCFHFL*SNPFNAFTSSCLAAQL
SLQKKVKKK*MMV*KIHTFMNNQSDFSELCVQK
INVHSYILVKGVCVFLKYIHPYFICIYI*IWID
NRYICVCYIF*SSFHWGIFFPFYSTPTTAFISLF
PLPSSPTFFSQSYQ*HSNVDVSGSFEYKIWQT

Frame 1

LPDGTPLCPRLTSPLPLA*SCAVFRPRLFRPRA
FGVRLLRGSRRRPRLGAE*ECPSRRAASPPGPP
PCRQWRAPFSLEALPPAP*MEIGSAGPAGAQPLL
MVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYL
YEVDIKPDKCPRRVNR*I*TLLYLGKVEKIDLS
RCQSNLSLG*VGTYCMKY*QDGPCLSHWN*TSQS
ALT
LSMPLMWCYDICPP*ISATAFYKAQPVIQF
MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLK
VEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLEN
GQTVERTVAQYFREKYTLQLKYPHLPCLQVGQE
QKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIK
ATARSAPDRQEEISRLVRSANYETDPFVQEFQFK
VRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHG
VWDMRGKQFHTGVEIKMWAIACFATQRQCREEI
LKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADS
VEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVK
RVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLK
INVKLGGINNILVPHQRPSVFQQPVIFLGADVTH
PPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQR
PRQEIIQDLASMVRELLIQFYKSTRFKPTRIIF
YRDGVSEGQFRQVLYYELLAIREACISLEKDYQP
GITYIVVQKRHHTRLFCADRTERVGRSGNIPAG
TTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYH
VLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIP
APAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQ
SNGRDPQALAKAVQIHQDTLRTMYFA*IVQVYS
LRGSTER*IDIQRMFPVKSIE*GHLQPYRNQHCV
GAKV*SLC*YKEDCLLHQGTQHHYAI*NQPTAF
CAVSYRKYRNCFVFISCSLTLLMPLPQVAWQHN
YLCKKK*RKSK*WFKKYTPS*IIKVIFQNYVCKK
LMCIHIFL*KVSVYF*NIYIHTSYAYISRSGLI
IDIYVSVIYFRVHSIGEFSFPFILPPLPPLFLY
FPCLHHLHFFPSPTSDIQMLMYLVRLNIKYGKL

Frame 2

FRTGLPSVRASHLPFLSPSPVPFSVRDSSGPEL
SECGCSGEAVAAPASGPSESARRVAPRRPPGRL
LAASGGLRSPSKHSPQLHEWKSAPQDPLGPSPY
SWCPEDLAMAPWANPLNCWLTVFKLKSQRLMSTS
MR*ILNQTSVLGE*TGRFRRYFTWGRWKRSTFQ
GVNQICLSGELAPTA*STDRTDLA*ATGIRQAN
QH*P
CPCR*CGATTSALHEFLPLPSTKHNL*FSS
CVKFLIFIILMSNQDL*LILIG*NSPKR*KV*R
LK*LIVEQ*DGNTVFVM*QGGLPVIKPFLYS*K
TAKLWREQ*RSISEKSILFS*STRTFPVCKSGRN
RNTPTCH*KSVILWQGNDVSRS*QTIRLPL*SR
QQQDLHQIDKRKLADW*EVQIMKQIHLFRSFNL
KFGMKWLM*LDAYFQHLCSSMEDGIGQ*QHRAME
YGTCEGNNSTQELKSKCGLSLVLPHRGSAEKKY
*RVSQTSCVRFLRMQGCPSRASHASANMHRGQT
A*SPCSGISRTHILAYSLLSSSCRGRHQCMRK*N
V*ETHFWVWLHNVFKSRM**KHLLKLCQTCA*R
*MLNSEGSIIFLYLIKDLLCSSNQ*SFWEPMSL
IHLLVMERSLLLLLL*VVWMHTQADTVPQ*EFRD
PDRRSSRTWPPWSGNFLFNFISQLGSSLLVSSF
IGMVFQRGSLGRYYIMNY*QFEKPASVWRKTIN
LE*PTL*FRRDITLDYFVLIGQKGLEEVAISQLE
QQLIQTLHTHMSSIFTSVAMLEYRVPVVLHTIM
FYGMITALLQMNFSC*LTSSATLTYAVHDLFLY
LHQRIMLTW*HLEPDIILWTKNMTVLKEVTFQDK
AMGEIHKLLPRLYRFTKIPYAQCTSLK*SKYIL
*EEVLKDELTYNVCFQ*SQLSKDTSSHTETNTV
WGPRSDPYVNTRKIVYFIKEHSIIMQYETSQLLF
VRSPIGSIAIVLFSFLVV*PF*CLYLKLLGSTT
IFAKKSKEKVNDGLKNTHLHE*SK*FFRIMCAK
N*CAFIYSCKRCLCIFKIYTSILHMHIYLDLD**
*IYMCLLYILEFIPLGNFLSLLFYPHYRLYFSI
SLAFITYIFFPVLPVTFKC*CIWFV*I*NMAN

Sequence NM_024852

ACTTCCGGACGGGACTCCCCTCTGTCCGCGCCTCACATCTCCCCTTCCTCTCGCCTAGTCCTGTGCCGTTTTCCGTCCGCGACTCTTCCGGCCCAGAGCT
TTCGGAGTGCGGTTGCTCAGGGGAAGCCGTCGCCGCCCCCGCCTCGGGGCCGAGTGAGAGTGCCCGTCGCGTCGCGCCGCGTCGCCCCCCGGGCCGCCTC
CTTGCCGCCAGTGGCGGGCTCCGTTCTCCCTCGAAGCACTCCCCCCAGCTCCATGAATGGAAATCGGCTCCGCAGGACCCGCTGGGGCCCAGCCCCTACT
CATGGTGCCCAGAAGACCTGGCTATGGCACCATGGGCAAACCCATTAAACTGCTGGCTAACTGTTTTCAAGTTGAAATCCCAAAGATTGATGTCTACCTC
TATGAGGTAGATATTAAACCAGACAAGTGTCCTAGGAGAGTGAACAGGGAGGTGGTTGACTCAATGGTTCAGCATTTTAAAGTAACTATATTTGGAGACC
GTAGACCAGTTTATGATGGAAAAAGAAGTCTTTACACCGCCAATCCACTTCCTGTGGCAACTACAGGG
GTAGATTTAGACGTTACTTTACCTGGGGAAGG
TGGAAAAGATCGACCTTTCAAGGTGTCAATCAAATTTGTCTCTCGGGTGAGTTGGCACCTACTGCATGAAGTACTGACAGGACGGACCTTGCCTGAGCCA
CTGGAATTAGACAAGCCAATCAGCACTAACCCTGTCCATGCCGTTGATGTGGTGCTACGACATCTGCCCTCCATGAAATACACACCTGTGGGGCGTTCAT
TTTTCTCCGCTCCAGAAGGATATGACCACCCTCTGGGAGGGGGCAGGGAAGTGTGGTTTGGATTCCATCAGTCTGTTCGGCCTGCCATGTGGAAAATGAT
GCTTAATATCGATGTTTCTGCCACTGCCTTCTACAAAGCACAACCTGTAATTCAGTTCATGTGTGAAGTTCTTGATATTCATAATATTGATGAGCAACCA
AGACCTCTGACTGATTCTCATCGGGTAAAATTCACCAAAGAGATAAAAGGTTTGAAGGTTGAAGTGACTCATTGTGGAACAATGAGACGGAAATACCGTG
TTTGTAATGTAACAAGGAGGCCTGCCAGTCATCAAACCTTTCCTTTACAGTTAGAAAACGGCCAAACTGTGGAGAGAACAGTAGCGCAGTATTTCAGAGA
AAAGTATACTCTTCAGCTGAAGTACCCGCACCTTCCCTGTCTGCAAGTCGGGCAGGAACAGAAACACACCTACCTGCCACTAGAAGTCTGTAATATTGTG
GCAGGGCAACGATGTATCAAGAAGCTAACAGACAATCAGACTTCCACTATGATCAAGGCAACAGCAAGATCTGCACCAGATAGACAAGAGGAAATTAGCA
GATTGGTAAGAAGTGCAAATTATGAAACAGATCCATTTGTTCAGGAGTTTCAATTTAAAGTTCGGGATGAAATGGCTCATGTAACTGGACGCGTACTTCC
AGCACCTATGCTCCAGTATGGAGGACGGAATCGGACAGTAGCAACACCGAGCCATGGAGTATGGGACATGCGAGGGAAACAATTCCACACAGGAGTTGAA
ATCAAAATGTGGGCTATCGCTTGTTTTGCCACACAGAGGCAGTGCAGAGAAGAAATATTGAAGGGTTTCACAGACCAGCTGCGTAAGATTTCTAAGGATG
CAGGGATGCCCATCCAGGGCCAGCCATGCTTCTGCAAATATGCACAGGGGGCAGACAGCGTAGAGCCCATGTTCCGGCATCTCAAGAACACATATTCTGG
CCTACAGCTTATTATCGTCATCCTGCCGGGGAAGACACCAGTGTATGCGGAAGTGAAACGTGTAGGAGACACACTTTTGGGTATGGCTACACAATGTGTT
CAAGTCAAGAATGTAATAAAAACATCTCCTCAAACTCTGTCAAACTTGTGCCTAAAGATAAATGTTAAACTCGGAGGGATCAATAATATTCTTGTACCTC
ATCAAAGACCTTCTGTGTTCCAGCAACCAGTGATCTTTTTGGGAGCCGATGTCACTCATCCACCTGCTGGTGATGGAAAGAAGCCTTCTATTGCTGCTGT
TGTAGGTAGTATGGATGCACACCCAAGCAGATACTGTGCCACAGTAAGAGTTCAGAGACCCCGACAGGAGATCATCCAGGACTTGGCCTCCATGGTCCGG
GAACTTCTTATTCAATTTTATAAGTCAACTCGGTTCAAGCCTACTCGTATCATCTTTTATCGGGATGGTGTTTCAGAGGGGCAGTTTAGGCAGGTATTAT
ATTATGAACTACTAGCAATTCGAGAAGCCTGCATCAGTTTGGAGAAAGACTATCAACCTGGAATAACCTACATTGTAGTTCAGAAGAGACATCACACTCG
ATTATTTTGTGCTGATAGGACAGAAAGGGTTGGAAGAAGTGGCAATATCCCAGCTGGAACAACAGTTGATACAGACATTACACACCCATATGAGTTCGAT
TTTTACCTCTGTAGCCATGCTGGAATACAGGGTACCAGTCGTCCTTCACACTATCATGTTTTATGGGATGATAACTGCTTTACTGCAGATGAACTTCAGC
TGCTAACTTACCAGCTCTGCCACACTTACGTACGCTGTACACGATCTGTTTCTATACCTGCACCAGCGTATTATGCTCACCTGGTAGCATTTAGAGCCAG
ATATCATCTTGTGGACAAAGAACATGACAGTGCTGAAGGAAGTCACGTTTCAGGACAAAGCAATGGGCGAGATCCACAAGCTCTTGCCAAGGCTGTACAG
ATTCACCAAGATACCTTACGCACAATGTACTTCGCTTAAATAGTCCAAGTATATTCTCTGAGAGGAAGTACTGAAAGATGAATTGACATACAACGTATGT
TTCCAGTGAAGTCAATTGAGTAAGGACACCTCCAGCCATACAGAAACCAACACTGTGTGGGGGCCAAGGTCTGATCCTTATGTTAATACAAGGAAGATTG
TTTACTTCATCAAGGAACACAGCATCATTATGCAATATGAAACCAGCCAACTGCTTTTTGTGCGGTCTCCTATAGGAAGTATCGCAATTGTTTTGTTTTC
ATTTCTTGTAGTCTAACCCTTTTAATGCCTTTACCTCAAGTTGCTTGGCAGCACAACTATCTTTGCAAAAAAAAGTAAAGAAAAAGTAAATGATGGTTTA
AAAAATACACACCTTCATGAATAATCAAAGTGATTTTTCAGAATTATGTGTGCAAAAAATTAATGTGCATTCATATATTCTTGTAAAAGGTGTCTGTGTA
TTTTTAAAATATATACATCCATACTTCATATGCATATATATCTAGATCTGGATTGATAATAGATATATATGTGTCTGTTATATATTTTAGAGTTCATTCC
ATTGGGGAATTTTCTTTCCCTTTTATTCTACCCCCACTACCGCCTTTATTTCTCTATTTCCCTTGCCTTCATCACCTACATTTTTTTCCCAGTCCTACCA
GTGACATTCAAATGTTGATGTATCTGGTTCGTTTGAATATAAAATATGGCAAACTA
  • refseq_EIF2C3.F4 (forward primer)
  • refseq_EIF2C3.R4 (reverse primer)
  • Single exon skipping

Frame 0

TSGRDSPLSAPHISPSSRLVLCRFPSATLPAQS
FRSAVAQGKPSPPPPRGRVRVPVASRRVAPRAAS
LPPVAGSVLPRSTPPSSMNGNRLRRTRWGPAPT
HGAQKTWLWHHGQTH*TAG*LFSS*NPKD*CLP
L*GRY*TRQVS*ESEQGGG*LNGSAF*SNYIWRP
*TSL*WKKKSLHRQSTSCGNYR
GRFRRYFTWGR
WKRSTFQGVNQICLSGELAPTA*STDRTDLA*A
TGIRQANQH*PCPCR*CGATTSALHEIHTCGAFI
FLRSRRI*PPSGRGQGSVVWIPSVCSACHVEND
A*YRCFCHCLLQSTTCNSVHV*SS*YS*Y**AT
KTSD*FSSGKIHQRDKRFEG*SDSLWNNETEIPC
L*CNKEACQSSNLSFTVRKRPNCGENSSAVFQR
KVYSSAEVPAPSLSASRAGTETHLPATRSL*YC
GRATMYQEANRQSDFHYDQGNSKICTR*TRGN*Q
IGKKCKL*NRSICSGVSI*SSG*NGSCNWTRTS
STYAPVWRTESDSSNTEPWSMGHARETIPHRS*
NQNVGYRLFCHTEAVQRRNIEGFHRPAA*DF*GC
RDAHPGPAMLLQICTGGRQRRAHVPASQEHIFW
PTAYYRHPAGEDTSVCGSETCRRHTFGYGYTMC
SSQECNKNISSNSVKLVPKDKC*TRRDQ*YSCTS
SKTFCVPATSDLFGSRCHSSTCW*WKEAFYCCC
CR*YGCTPKQILCHSKSSETPTGDHPGLGLHGP
GTSYSIL*VNSVQAYSYHLLSGWCFRGAV*AGII
L*TTSNSRSLHQFGERLSTWNNLHCSSEETSHS
IILC**DRKGWKKWQYPSWNNS*YRHYTPI*VR
FLPL*PCWNTGYQSSFTLSCFMG**LLYCR*TSA
ANLPALPHLRTLYTICFYTCTSVLCSPGSI*SQ
ISSCGQRT*QC*RKSRFRTKQWARSTSSCQGCT
DSPRYLTHNVLRLNSPSIFSERKY*KMN*HTTYV
SSEVN*VRTPPAIQKPTLCGGQGLILMLIQGRL
FTSSRNTASLCNMKPANCFLCGLL*EVSQLFCF
HFL*SNPFNAFTSSCLAAQLSLQKKVKKK*MMV*
KIHTFMNNQSDFSELCVQKINVHSYILVKGVCV
FLKYIHPYFICIYI*IWIDNRYICVCYIF*SSF
HWGIFFPFYSTPTTAFISLFPLPSSPTFFSQSYQ
*HSNVDVSGSFEYKIWQT

Frame 1

LPDGTPLCPRLTSPLPLA*SCAVFRPRLFRPRA
FGVRLLRGSRRRPRLGAE*ECPSRRAASPPGPP
PCRQWRAPFSLEALPPAP*MEIGSAGPAGAQPLL
MVPRRPGYGTMGKPIKLLANCFQVEIPKIDVYL
YEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGD
RRPVYDGKRSLYTANPLPVATTG
VDLDVTLPGEG
GKDRPFKVSIKFVSRVSWHLLHEVLTGRTLPEP
LELDKPISTNPVHAVDVVLRHLPSMKYTPVGRS
FFSAPEGYDHPLGGGREVWFGFHQSVRPAMWKMM
LNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQP
RPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYR
VCNVTRRPASHQTFPLQLENGQTVERTVAQYFRE
KYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIV
AGQRCIKKLTDNQTSTMIKATARSAPDRQEEIS
RLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLP
APMLQYGGRNRTVATPSHGVWDMRGKQFHTGVE
IKMWAIACFATQRQCREEILKGFTDQLRKISKD
AGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSG
LQLIIVILPGKTPVYAEVKRVGDTLLGMATQCV
QVKNVIKTSPQTLSNLCLKINVKLGGINNILVP
HQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAV
VGSMDAHPSRYCATVRVQRPRQEIIQDLASMVR
ELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVL
YYELLAIREACISLEKDYQPGITYIVVQKRHHTR
LFCADRTERVGRSGNIPAGTTVDTDITHPYEFD
FYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQ
LLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRAR
YHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQ
IHQDTLRTMYFA*IVQVYSLRGSTER*IDIQRM
FPVKSIE*GHLQPYRNQHCVGAKV*SLC*YKEDC
LLHQGTQHHYAI*NQPTAFCAVSYRKYRNCFVF
ISCSLTLLMPLPQVAWQHNYLCKKK*RKSK*WF
KKYTPS*IIKVIFQNYVCKKLMCIHIFL*KVSVY
F*NIYIHTSYAYISRSGLIIDIYVSVIYFRVHS
IGEFSFPFILPPLPPLFLYFPCLHHLHFFPSPT
SDIQMLMYLVRLNIKYGKL

Frame 2

FRTGLPSVRASHLPFLSPSPVPFSVRDSSGPEL
SECGCSGEAVAAPASGPSESARRVAPRRPPGRL
LAASGGLRSPSKHSPQLHEWKSAPQDPLGPSPY
SWCPEDLAMAPWANPLNCWLTVFKLKSQRLMSTS
MR*ILNQTSVLGE*TGRWLTQWFSILK*LYLET
VDQFMMEKEVFTPPIHFLWQLQG
*I*TLLYLGK
VEKIDLSRCQSNLSLG*VGTYCMKY*QDGPCLSH
WN*TSQSALTLSMPLMWCYDICPP*NTHLWGVH
FSPLQKDMTTLWEGAGKCGLDSISLFGLPCGK*
CLISMFLPLPSTKHNL*FSSCVKFLIFIILMSNQ
DL*LILIG*NSPKR*KV*RLK*LIVEQ*DGNTV
FVM*QGGLPVIKPFLYS*KTAKLWREQ*RSISE
KSILFS*STRTFPVCKSGRNRNTPTCH*KSVILW
QGNDVSRS*QTIRLPL*SRQQQDLHQIDKRKLA
DW*EVQIMKQIHLFRSFNLKFGMKWLM*LDAYF
QHLCSSMEDGIGQ*QHRAMEYGTCEGNNSTQELK
SKCGLSLVLPHRGSAEKKY*RVSQTSCVRFLRM
QGCPSRASHASANMHRGQTA*SPCSGISRTHIL
AYSLLSSSCRGRHQCMRK*NV*ETHFWVWLHNVF
KSRM**KHLLKLCQTCA*R*MLNSEGSIIFLYL
IKDLLCSSNQ*SFWEPMSLIHLLVMERSLLLLL
L*VVWMHTQADTVPQ*EFRDPDRRSSRTWPPWSG
NFLFNFISQLGSSLLVSSFIGMVFQRGSLGRYY
IMNY*QFEKPASVWRKTINLE*PTL*FRRDITL
DYFVLIGQKGLEEVAISQLEQQLIQTLHTHMSSI
FTSVAMLEYRVPVVLHTIMFYGMITALLQMNFS
C*LTSSATLTYAVHDLFLYLHQRIMLTW*HLEP
DIILWTKNMTVLKEVTFQDKAMGEIHKLLPRLYR
FTKIPYAQCTSLK*SKYIL*EEVLKDELTYNVC
FQ*SQLSKDTSSHTETNTVWGPRSDPYVNTRKI
VYFIKEHSIIMQYETSQLLFVRSPIGSIAIVLFS
FLVV*PF*CLYLKLLGSTTIFAKKSKEKVNDGL
KNTHLHE*SK*FFRIMCAKN*CAFIYSCKRCLC
IFKIYTSILHMHIYLDLD***IYMCLLYILEFIP
LGNFLSLLFYPHYRLYFSISLAFITYIFFPVLP
VTFKC*CIWFV*I*NMAN

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