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Sequences

Sequence NM_182799

GACAACTGAGACGGCTGCAGACCATGGGGCAGGGAGCATATGGAGCACGGATATGCCAGACAGAGGGATGATTCATATCCCAGGCAGGATGGAGCAGGGC AGTGTGCTATTTCATCGTGCTACTCAGAACTTATGAATTGTTTATTTCTGGAATTTCCCATTTAATATTTTTGGACTGTGGTTGATCGAGGGTAAATGAA ATTGCAGAAAGCAAAAATACAGATAAGGGGGACTGCTTGCTGTACAAAGATAGAGACAAGAGGAAGGAGCTGTCCTCAAGGGCCTTTTGTGTGAAGACAT CTGGCACACAGATACGCTGCATGCAGGTGGCTTGAGAGAACATGCATCCAGGTTTAATTGTGGAACTGGGGTTGCCATCATCGTAAGTGAGACCAAAATC AAACTAGGGGGTTGGCACACGGTTATGCTCTACAGAGATGGGCTGAACGGGCTGCTGCAGCTGAACAATGGCACCCCAGTGACAGGCCAGTCTCAGGGGA ATGCAGCAGTGGAATCTGTGATGAGGCCTCGTGCATCCATGGTGGCACCTGCACAGCAATCAAAGCCGACTCCTACATTTGCCTCTGTCCCCTTGGGTTT AAAGGTCGACACTGTGAAGATGCTTTCACCTTGACCATTCCTCAGTTCAGAGAGTCTCTGAGATCTTACGCTGCAACTCCCTGGCCACTGGAGCCCCAGC ATTACCTTTCCTTCATGGAATTTGAGATCACATTTCGGCCAGACTCAGGAGATGGTGTCCTCCTGTACAGCTATGACACAGGCAGCAAAGACTTCCTGTC CATCAACTTGGCAGGGGGCCACGTGGAGTTCCGCTTTGACTGTGGCTCTGGGACCGGTGTCCTCAGGAGTGAAGATCCCCTCACCCTGGGCAACTGGCAC GAGCTTCGTGTATCTCGCACAGCAAAGAATGGAATCTTACAGGTGGATAAGCAGAAGATAGTGGAGGGAATGGCAGAGGGAGGCTTCACACAGATTAAGT GCAACACAGACATTTTCATTGGCGGAGTCCCCAATTATGATGATGTGAAGAAGAACTCGGGTGTCCTGAAGCCTTTCAGCGGGAGCATCCAGAAGATCAT CCTGAATGACCGAACCATCCATGTGAAGCATGACTTCACCTCCGGAGTGAATGTGGAGAATGCGGCCCACCCCTGTGTGAGAGCCCCTTGTGCCCATGGG GGCAGCTGCCGGCCCAGGAAGGAGGGCTATGACTGTGACTGCCCCTTGGGCTTTGAGGGGCTTCACTGCCAGAAAGCGATCATAGAAGCCATTGAGATCC CGCAGTTTATCGGCCGCAGTTACCTGACGTATGACAACCCAGATATCTTGAAGAGGGTGTCAGGATCAAGATCAAATGTGTTCATGAGGTTTAAAACAAC TGCCAAGGATGGCCTTTTGCTGTGGAGGGGAGACAGCCCCATGAGACCCAACAGCGACTTCATTTCCTTGGGCCTTCGGGATGGAGCCCTCGTGTTCAGC TATAACCTGGGCAGTGGTGTGGCATCCATCATGGTGAATGGCTCCTTCAACGATGGTCGGTGGCACCGAGTTAAGGCCGTTAGGGATGGCCAGTCAGGAA AGATAACCGTGGATGACTATGGAGCCAGAACAGGCAAATCCCCAGGCATGATGCGGCAGCTTAACATCAATGGAGCTCTGTATGTGGGTGGAATGAAGGA AATTGCTCTGCACACTAACAGGCAATATATGAGAGGGCTCGTGGGCTGTATCTCTCACTTCACCCTGTCCACCGATTACCACATTTCCCTCGTGGAAGAT GCCGTGGATGGGAAAAACATCAACACTTGTGGAGCCAAGTAACACCAGCTGGCCTTGTCCAAGGGACAGAGCCTTCTATTCTGAGAATCCCAGGGGCCCT CAGACCCTGCCTGATGCTATATGCAGAGGCCCAGGGACCAGGTGTGTTTCCTCTCACCAAGAAGAAAGTACACACTGATGAGAAACTGAGAACCAAGACA GGCATCCCTGGGTGGCCTTTCCTGCTGACACTCCACGAGCTGACCCAGCAGAATTCTCTGTGTAGGAAGCATCGGACTTTGTCCATTGAATATGTAGCGG CTGCCAGAGATCACACATCAATGCAAATTCCAGAGCCTGTCTGCTATAGCTCAGTGACTGTGTTGTGATTCATAGTACATTAAAAAGAGAGAGAGAGAGA AAGAATCCCACAGGGCACTATTAAAATACTTCTCTCCTTCCCTGACTCATGACACTCTTCCTGACAGCAGAATGACTGTGTGACCTTGAACTTCACATTT CCCACATTGGCCCTTGGATTGTTCGGATTAACCCCTTCCACTCCTCACTGGCTGGTTCACTGTGTTCTGACTAGTCCATAAAAATAAAGATGGAAGGAGA TCAAACACAGAATCATAATCATAATGCGGCCCCCTTCCCCAGAGCTTACCTCGAATGTGAAATCCCTACTTCTTATAATGCAGAGTTAAGGAGCTGAGCC CCCATGATTTTGTAGCTGTACTTTTGTATGTGTATATTTTTATAGCTGCAGATTGTCCACACAGTATACTTTTGGAAGTTTGGGTGGATGACTCTGAATT CTTGCACACCTTTCCTAAAAATTTCTCCCAAGAGAGACTTGTTTGGGCCTTTTGTGGTGTCAGTGGAATGGATAGGTAACTTGGGTGGGCAACTTGGGGA GCTGACCATTCTCTTTTGGTAAATGTTGACGGCTCAAGAGGATGAATATGAAGCTTTCCAAGATAAGCAGATTAAAAGGAACATGTGTTACCGAGGTAGG TCACTGTCATTTTTGTTTTAAGAGTTGGGGGGAGTATCTATAGTAAACTTGAATAAAGGGGACAAAGCTAGAACTTATTCATTCATTCATTCACTTATGG AGTTGTTACTGATTTTGCGGAGGTCAGGTTCATACCAATGGACACTAATACAATCAGTGTTCCCAAGGCTGTGCAGGGGTGGGGGGACATGCTGTCAGGA TGGTCTGAGCATCTGGGTGAGAACCAGAGAAACAGGACTTCTTCCTTCTGTACCATGAGCTGTGTCCCTTTACTATGCAAGCACATGACCCCAGAGACAG CTGGTTCACTGGCAGATCCCCATGATGGACTTACTAAGGGAAAGGTGAGATGAACACTGCCCCCAAGGAGGGGGTGAAATATGATCTAACTTATGCAAGA GCCTATAATTAGTCCCAGTCTCGACTCTACATTTGTTTGTGCAGCATTCATTCAGCAAAGACTTTTGGGGTTTGTGCAAGGCACAGTTTTAAGCACATAA TGTAATTCTAAAAGATGAATAAACTAGAGAGGTTC

refseq_EGFLAM.F1 (forward primer)
refseq_EGFLAM.R1 (reverse primer)
Single exon skipping

Frame 0

DN*DGCRPWGREHMEHGYARQRDDSYPRQDGAG QCAISSCYSELMNCLFLEFPI*YFWTVVDRG*MK LQKAKIQIRGTACCTKIETRGRSCPQGPFV*RH LAHRYAACRWLERTCIQV*LWNWGCHHRK*DQN QTRGLAHGYALQRWAERAAAAEQWHPSDRPVSGE CSSGICDEASCIHGGTCTAIKADSYICLCPLGF KGRHCEDAFTLTIPQFRESLRSYAATPWPLEPQ HYLSFMEFEITFRPDSGDGVLLYSYDTGSKDFLS INLAGGHVEFRFDCGSGTGVLRSEDPLTLGNWH ELRVSRTAKNGILQVDKQKIVEGMAEGGFTQIK CNTDIFIGGVPNYDDVKKNSGVLKPFSGSIQKII LNDRTIHVKHDFTSGVNVENAAHPCVRAPCAHG GSCRPRKEGYDCDCPLGFEGLHCQKAIIEAIEI PQFIGRSYLTYDNPDILKRVSGSRSNVFMRFKTT AKDGLLLWRGDSPMRPNSDFISLGLRDGALVFS YNLGSGVASIMVNGSFNDGRWHRVKAVRDGQSG KITVDDYGARTGKSPGMMRQLNINGALYVGGMKE IALHTNRQYMRGLVGCISHFTLSTDYHISLVED AVDGKNINTCGAK*HQLALSKGQSLLF*ESQGP SDPA*CYMQRPRDQVCFLSPRRKYTLMRN*EPRQ ASLGGLSC*HSTS*PSRILCVGSIGLCPLNM*R LPEITHQCKFQSLSAIAQ*LCCDS*YIKKRERE KESHRALLKYFSPSLTHDTLPDSRMTV*P*TSHF PHWPLDCSD*PLPLLTGWFTVF*LVHKNKDGRR SNTES*S*CGPLPQSLPRM*NPYFL*CRVKELS PHDFVAVLLYVYIFIAADCPHSILLEVWVDDSEF LHTFPKNFSQERLVWAFCGVSGMDR*LGWATWG ADHSLLVNVDGSRG*I*SFPR*AD*KEHVLPR* VTVIFVLRVGGSIYSKLE*RGQS*NLFIHSFTYG VVTDFAEVRFIPMDTNTISVPKAVQGWGDMLSG WSEHLGENQRNRTSSFCTMSCVPLLCKHMTPET AGSLADPHDGLTKGKVR*TLPPRRG*NMI*LMQE PIISPSLDSTFVCAAFIQQRLLGFVQGTVLST* CNSKR*IN*RG

Frame 1

TTETAADHGAGSIWSTDMPDRGMIHIPGRMEQG SVLFHRATQNL*IVYFWNFPFNIFGLWLIEGK* NCRKQKYR*GGLLAVQR*RQEEGAVLKGLLCEDI WHTDTLHAGGLREHASRFNCGTGVAIIVSETKI KLGGWHTVMLYRDGLNGLLQLNNGTPVTGQSQG NAAVESVMRPRASMVAPAQQSKPTPTFASVPLGL KVDTVKMLSP*PFLSSESL*DLTLQLPGHWSPS ITFPSWNLRSHFGQTQEMVSSCTAMTQAAKTSC PSTWQGATWSSALTVALGPVSSGVKIPSPWATGT SFVYLAQQRMESYRWISRR*WREWQREASHRLS ATQTFSLAESPIMMM*RRTRVS*SLSAGASRRS S*MTEPSM*SMTSPPE*MWRMRPTPV*EPLVPMG AAAGPGRRAMTVTAPWALRGFTARKRS*KPLRS RSLSAAVT*RMTTQIS*RGCQDQDQMCS*GLKQ LPRMAFCCGGETAP*DPTATSFPWAFGMEPSCSA ITWAVVWHPSW*MAPSTMVGGTELRPLGMASQE R*PWMTMEPEQANPQA*CGSLTSMELCMWVE*R KLLCTLTGNI*EGSWAVSLTSPCPPITTFPSWKM PWMGKTSTLVEPSNTSWPCPRDRAFYSENPRGP QTLPDAICRGPGTRCVSSHQEESTH**ETENQD RHPWVAFPADTPRADPAEFSV*EASDFVH*ICSG CQRSHINANSRACLL*LSDCVVIHSTLKRERER KNPTGHY*NTSLLP*LMTLFLTAE*LCDLELHI SHIGPWIVRINPFHSSLAGSLCSD*SIKIKMEGD QTQNHNHNAAPFPRAYLECEIPTSYNAELRS*A PMIL*LYFCMCIFL*LQIVHTVYFWKFGWMTLN SCTPFLKISPKRDLFGPFVVSVEWIGNLGGQLGE LTILFW*MLTAQEDEYEAFQDKQIKRNMCYRGR SLSFLF*ELGGVSIVNLNKGDKARTYSFIHSLM ELLLILRRSGSYQWTLIQSVFPRLCRGGGTCCQD GLSIWVRTRETGLLPSVP*AVSLYYAST*PQRQ LVHWQIPMMDLLRER*DEHCPQGGGEI*SNLCK SL*LVPVSTLHLFVQHSFSKDFWGLCKAQF*AHN VILKDE*TREV

Frame 2

QLRRLQTMGQGAYGARICQTEG*FISQAGWSRA VCYFIVLLRTYELFISGISHLIFLDCG*SRVNE IAESKNTDKGDCLLYKDRDKRKELSSRAFCVKT SGTQIRCMQVA*ENMHPGLIVELGLPSS*VRPKS N*GVGTRLCSTEMG*TGCCS*TMAPQ*QASLRG MQQWNL**GLVHPWWHLHSNQSRLLHLPLSPWV *RSTL*RCFHLDHSSVQRVSEILRCNSLATGAPA LPFLHGI*DHISARLRRWCPPVQL*HRQQRLPV HQLGRGPRGVPL*LWLWDRCPQE*RSPHPGQLA RASCISHSKEWNLTGG*AEDSGGNGRGRLHTD*V QHRHFHWRSPQL**CEEELGCPEAFQREHPEDH PE*PNHPCEA*LHLRSECGECGPPLCESPLCPW GQLPAQEGGL*L*LPLGL*GASLPESDHRSH*DP AVYRPQLPDV*QPRYLEEGVRIKIKCVHEV*NN CQGWPFAVEGRQPHETQQRLHFLGPSGWSPRVQ L*PGQWCGIHHGEWLLQRWSVAPS*GR*GWPVRK DNRG*LWSQNRQIPRHDAAA*HQWSSVCGWNEG NCSAH*QAIYERARGLYLSLHPVHRLPHFPRGR CRGWEKHQHLWSQVTPAGLVQGTEPSILRIPGAL RPCLMLYAEAQGPGVFPLTKKKVHTDEKLRTKT GIPGWPFLLTLHELTQQNSLCRKHRTLSIEYVA AARDHTSMQIPEPVCYSSVTVL*FIVH*KERERE RIPQGTIKILLSFPDS*HSS*QQNDCVTLNFTF PTLALGLFGLTPSTPHWLVHCVLTSP*K*RWKE IKHRIIIIMRPPSPELTSNVKSLLLIMQS*GAEP P*FCSCTFVCVYFYSCRLSTQYTFGSLGG*L*I LAHLS*KFLPRETCLGLLWCQWNG*VTWVGNLG S*PFSFGKC*RLKRMNMKLSKISRLKGTCVTEVG HCHFCFKSWGEYL**T*IKGTKLELIHSFIHLW SCY*FCGGQVHTNGH*YNQCSQGCAGVGGHAVR MV*ASG*EPEKQDFFLLYHELCPFTMQAHDPRDS WFTGRSP*WTY*GKGEMNTAPKEGVKYDLTYAR AYN*SQSRLYICLCSIHSAKTFGVCARHSFKHI M*F*KMNKLERF

Sequence NM_182798

GACAACTGAGACGGCTGCAGACCATGGGGCAGGGAGCATATGGAGCACGGATATGCCAGACAGAGGGATGATTCATATCCCAGGCAGGATGGAGCAGGGC AGTGTGCTATTTCATCGTGCTACTCAGAACTTATGAATTGTTTATTTCTGGAATTTCCCATTTAATATTTTTGGACTGTGGTTGATCGAGGGTAAATGAA ATTGCAGAAAGCAAAAATACAGATAAGGGGGACTGCTTGCTGTACAAAGATAGAGACAAGAGGAAGGAGCTGTCCTCAAGGGCCTTTTGTGTGAAGACAT CTGGCACACAGATACGCTGCATGCAGGTGGCTTGAGAGAACATGCATCCAGGCCCTGAGGAGGCGGGAAGTGGCCGCTATGGACCCCGTTATATCACCGA CATGGGAGCTGGTGAGGATGATGAAGGATTTGAAGACGACTTAGATTTGGATATTTCCTTTGAGGAGGTTAAACCACTTCCTGCTACCAAAGGAGGGAAT AAGAAATTTTTGGTGGAAAGCAAGAAGATGTCTATATCTAACCCAAAGACCATTTCTAGGCTCATCCCCCCTACCTCAGCATCTCTCCCTGTGACCACGG TGGCTCCCCAGCCCATTCCCATACAGAGAAAGGGGAAGAATGGTGTGGCCATAATGTCAAGGCTCTTTGACATGCCTTGTGATGAAACTCTCTGCTCTGC TGACAGCTTCTGTGTCAATGACTACACCTGGGGGGGCTCGCGATGCCAGTGCACCCTGGGCAAAGGTGGTGAGAGCTGCTCAGAAGATATTGTTATCCAG TATCCTCAGTTCTTTGGCCACTCCTATGTAACGTTTGAACCTCTGAAGAATTCTTATCAGGCATTTCAAATTACTCTTGAATTTAGGGCGGAGGCAGAGG ATGGCTTACTGCTCTACTGTGGGGAGAACGAACACGGGAGGGGGGATTTCATGTCCCTGGCTATCATCCGACGCTCCCTGCAGTTCAGGTTTAATTGTGG AACTGGGGTTGCCATCATCGTAAGTGAGACCAAAATCAAACTAGGGGGTTGGCACACGGTTATGCTCTACAGAGATGGGCTGAACGGGCTGCTGCAGCTG AACAATGGCACCCCAGTGACAGGCCAGTCTCAGGGCCAATACAGTAAAATTACTTTCCGGACACCTCTCTATCTTGGTGGCGCTCCCAGCGCTTACTGGT TGGTTAGAGCAACAGGGACAAACCGAGGCTTTCAAGGCTGTGTGCAGTCGCTCGCTGTGAATGGGAGGAGAATTGACATGAGGCCCTGGCCCCTGGGAAA AGCACTCAGTGGGGCTGATGTGGGGGAATGCAGCAGTGGAATCTGTGATGAGGCCTCGTGCATCCATGGTGGCACCTGCACAGCAATCAAAGCCGACTCC TACATTTGCCTCTGTCCCCTTGGGTTTAAAGGTCGACACTGTGAAGATGCTTTCACCTTGACCATTCCTCAGTTCAGAGAGTCTCTGAGATCTTACGCTG CAACTCCCTGGCCACTGGAGCCCCAGCATTACCTTTCCTTCATGGAATTTGAGATCACATTTCGGCCAGACTCAGGAGATGGTGTCCTCCTGTACAGCTA TGACACAGGCAGCAAAGACTTCCTGTCCATCAACTTGGCAGGGGGCCACGTGGAGTTCCGCTTTGACTGTGGCTCTGGGACCGGTGTCCTCAGGAGTGAA GATCCCCTCACCCTGGGCAACTGGCACGAGCTTCGTGTATCTCGCACAGCAAAGAATGGAATCTTACAGGTGGATAAGCAGAAGATAGTGGAGGGAATGG CAGAGGGAGGCTTCACACAGATTAAGTGCAACACAGACATTTTCATTGGCGGAGTCCCCAATTATGATGATGTGAAGAAGAACTCGGGTGTCCTGAAGCC TTTCAGCGGGAGCATCCAGAAGATCATCCTGAATGACCGAACCATCCATGTGAAGCATGACTTCACCTCCGGAGTGAATGTGGAGAATGCGGCCCACCCC TGTGTGAGAGCCCCTTGTGCCCATGGGGGCAGCTGCCGGCCCAGGAAGGAGGGCTATGACTGTGACTGCCCCTTGGGCTTTGAGGGGCTTCACTGCCAGA AAGCGATCATAGAAGCCATTGAGATCCCGCAGTTTATCGGCCGCAGTTACCTGACGTATGACAACCCAGATATCTTGAAGAGGGTGTCAGGATCAAGATC AAATGTGTTCATGAGGTTTAAAACAACTGCCAAGGATGGCCTTTTGCTGTGGAGGGGAGACAGCCCCATGAGACCCAACAGCGACTTCATTTCCTTGGGC CTTCGGGATGGAGCCCTCGTGTTCAGCTATAACCTGGGCAGTGGTGTGGCATCCATCATGGTGAATGGCTCCTTCAACGATGGTCGGTGGCACCGAGTTA AGGCCGTTAGGGATGGCCAGTCAGGAAAGATAACCGTGGATGACTATGGAGCCAGAACAGGCAAATCCCCAGGCATGATGCGGCAGCTTAACATCAATGG AGCTCTGTATGTGGGTGGAATGAAGGAAATTGCTCTGCACACTAACAGGCAATATATGAGAGGGCTCGTGGGCTGTATCTCTCACTTCACCCTGTCCACC GATTACCACATTTCCCTCGTGGAAGATGCCGTGGATGGGAAAAACATCAACACTTGTGGAGCCAAGTAACACCAGCTGGCCTTGTCCAAGGGACAGAGCC TTCTATTCTGAGAATCCCAGGGGCCCTCAGACCCTGCCTGATGCTATATGCAGAGGCCCAGGGACCAGGTGTGTTTCCTCTCACCAAGAAGAAAGTACAC ACTGATGAGAAACTGAGAACCAAGACAGGCATCCCTGGGTGGCCTTTCCTGCTGACACTCCACGAGCTGACCCAGCAGAATTCTCTGTGTAGGAAGCATC GGACTTTGTCCATTGAATATGTAGCGGCTGCCAGAGATCACACATCAATGCAAATTCCAGAGCCTGTCTGCTATAGCTCAGTGACTGTGTTGTGATTCAT AGTACATTAAAAAGAGAGAGAGAGAGAAAGAATCCCACAGGGCACTATTAAAATACTTCTCTCCTTCCCTGACTCATGACACTCTTCCTGACAGCAGAAT GACTGTGTGACCTTGAACTTCACATTTCCCACATTGGCCCTTGGATTGTTCGGATTAACCCCTTCCACTCCTCACTGGCTGGTTCACTGTGTTCTGACTA GTCCATAAAAATAAAGATGGAAGGAGATCAAACACAGAATCATAATCATAATGCGGCCCCCTTCCCCAGAGCTTACCTCGAATGTGAAATCCCTACTTCT TATAATGCAGAGTTAAGGAGCTGAGCCCCCATGATTTTGTAGCTGTACTTTTGTATGTGTATATTTTTATAGCTGCAGATTGTCCACACAGTATACTTTT GGAAGTTTGGGTGGATGACTCTGAATTCTTGCACACCTTTCCTAAAAATTTCTCCCAAGAGAGACTTGTTTGGGCCTTTTGTGGTGTCAGTGGAATGGAT AGGTAACTTGGGTGGGCAACTTGGGGAGCTGACCATTCTCTTTTGGTAAATGTTGACGGCTCAAGAGGATGAATATGAAGCTTTCCAAGATAAGCAGATT AAAAGGAACATGTGTTACCGAGGTAGGTCACTGTCATTTTTGTTTTAAGAGTTGGGGGGAGTATCTATAGTAAACTTGAATAAAGGGGACAAAGCTAGAA CTTATTCATTCATTCATTCACTTATGGAGTTGTTACTGATTTTGCGGAGGTCAGGTTCATACCAATGGACACTAATACAATCAGTGTTCCCAAGGCTGTG CAGGGGTGGGGGGACATGCTGTCAGGATGGTCTGAGCATCTGGGTGAGAACCAGAGAAACAGGACTTCTTCCTTCTGTACCATGAGCTGTGTCCCTTTAC TATGCAAGCACATGACCCCAGAGACAGCTGGTTCACTGGCAGATCCCCATGATGGACTTACTAAGGGAAAGGTGAGATGAACACTGCCCCCAAGGAGGGG GTGAAATATGATCTAACTTATGCAAGAGCCTATAATTAGTCCCAGTCTCGACTCTACATTTGTTTGTGCAGCATTCATTCAGCAAAGACTTTTGGGGTTT GTGCAAGGCACAGTTTTAAGCACATAATGTAATTCTAAAAGATGAATAAACTAGAGAGGTTC

refseq_EGFLAM.F1 (forward primer)
refseq_EGFLAM.R1 (reverse primer)
Single exon skipping

Frame 0

DN*DGCRPWGREHMEHGYARQRDDSYPRQDGAG QCAISSCYSELMNCLFLEFPI*YFWTVVDRG*MK LQKAKIQIRGTACCTKIETRGRSCPQGPFV*RH LAHRYAACRWLERTCIQALRRREVAAMDPVISP TWELVRMMKDLKTT*IWIFPLRRLNHFLLPKEGI RNFWWKARRCLYLTQRPFLGSSPLPQHLSL*PR WLPSPFPYRERGRMVWP*CQGSLTCLVMKLSAL LTASVSMTTPGGARDASAPWAKVVRAAQKILLSS ILSSLATPM*RLNL*RILIRHFKLLLNLGRRQR MAYCSTVGRTNTGGGISCPWLSSDAPCSSGLIV ELGLPSS*VRPKSN*GVGTRLCSTEMG*TGCCS* TMAPQ*QASLRANTVKLLSGHLSILVALPALTG WLEQQGQTEAFKAVCSRSL*MGGELT*GPGPWE KHSVGLMWGNAAVESVMRPRASMVAPAQQSKPTP TFASVPLGLKVDTVKMLSP*PFLSSESL*DLTL QLPGHWSPSITFPSWNLRSHFGQTQEMVSSCTA MTQAAKTSCPSTWQGATWSSALTVALGPVSSGVK IPSPWATGTSFVYLAQQRMESYRWISRR*WREW QREASHRLSATQTFSLAESPIMMM*RRTRVS*S LSAGASRRSS*MTEPSM*SMTSPPE*MWRMRPTP V*EPLVPMGAAAGPGRRAMTVTAPWALRGFTAR KRS*KPLRSRSLSAAVT*RMTTQIS*RGCQDQD QMCS*GLKQLPRMAFCCGGETAP*DPTATSFPWA FGMEPSCSAITWAVVWHPSW*MAPSTMVGGTEL RPLGMASQER*PWMTMEPEQANPQA*CGSLTSM ELCMWVE*RKLLCTLTGNI*EGSWAVSLTSPCPP ITTFPSWKMPWMGKTSTLVEPSNTSWPCPRDRA FYSENPRGPQTLPDAICRGPGTRCVSSHQEEST H**ETENQDRHPWVAFPADTPRADPAEFSV*EAS DFVH*ICSGCQRSHINANSRACLL*LSDCVVIH STLKRERERKNPTGHY*NTSLLP*LMTLFLTAE *LCDLELHISHIGPWIVRINPFHSSLAGSLCSD* SIKIKMEGDQTQNHNHNAAPFPRAYLECEIPTS YNAELRS*APMIL*LYFCMCIFL*LQIVHTVYF WKFGWMTLNSCTPFLKISPKRDLFGPFVVSVEWI GNLGGQLGELTILFW*MLTAQEDEYEAFQDKQI KRNMCYRGRSLSFLF*ELGGVSIVNLNKGDKAR TYSFIHSLMELLLILRRSGSYQWTLIQSVFPRLC RGGGTCCQDGLSIWVRTRETGLLPSVP*AVSLY YAST*PQRQLVHWQIPMMDLLRER*DEHCPQGG GEI*SNLCKSL*LVPVSTLHLFVQHSFSKDFWGL CKAQF*AHNVILKDE*TREV

Frame 1

TTETAADHGAGSIWSTDMPDRGMIHIPGRMEQG SVLFHRATQNL*IVYFWNFPFNIFGLWLIEGK* NCRKQKYR*GGLLAVQR*RQEEGAVLKGLLCEDI WHTDTLHAGGLREHASRP*GGGKWPLWTPLYHR HGSW*G**RI*RRLRFGYFL*GG*TTSCYQRRE *EIFGGKQEDVYI*PKDHF*AHPPYLSISPCDHG GSPAHSHTEKGEEWCGHNVKAL*HAL**NSLLC *QLLCQ*LHLGGLAMPVHPGQRW*ELLRRYCYP VSSVLWPLLCNV*TSEEFLSGISNYS*I*GGGRG WLTALLWGERTREGGFHVPGYHPTLPAVQV*LW NWGCHHRK*DQNQTRGLAHGYALQRWAERAAAA EQWHPSDRPVSGPIQ*NYFPDTSLSWWRSQRLLV G*SNRDKPRLSRLCAVARCEWEEN*HEALAPGK STQWG*CGGMQQWNL**GLVHPWWHLHSNQSRL LHLPLSPWV*RSTL*RCFHLDHSSVQRVSEILRC NSLATGAPALPFLHGI*DHISARLRRWCPPVQL *HRQQRLPVHQLGRGPRGVPL*LWLWDRCPQE* RSPHPGQLARASCISHSKEWNLTGG*AEDSGGNG RGRLHTD*VQHRHFHWRSPQL**CEEELGCPEA FQREHPEDHPE*PNHPCEA*LHLRSECGECGPP LCESPLCPWGQLPAQEGGL*L*LPLGL*GASLPE SDHRSH*DPAVYRPQLPDV*QPRYLEEGVRIKI KCVHEV*NNCQGWPFAVEGRQPHETQQRLHFLG PSGWSPRVQL*PGQWCGIHHGEWLLQRWSVAPS* GR*GWPVRKDNRG*LWSQNRQIPRHDAAA*HQW SSVCGWNEGNCSAH*QAIYERARGLYLSLHPVH RLPHFPRGRCRGWEKHQHLWSQVTPAGLVQGTEP SILRIPGALRPCLMLYAEAQGPGVFPLTKKKVH TDEKLRTKTGIPGWPFLLTLHELTQQNSLCRKH RTLSIEYVAAARDHTSMQIPEPVCYSSVTVL*FI VH*KERERERIPQGTIKILLSFPDS*HSS*QQN DCVTLNFTFPTLALGLFGLTPSTPHWLVHCVLT SP*K*RWKEIKHRIIIIMRPPSPELTSNVKSLLL IMQS*GAEPP*FCSCTFVCVYFYSCRLSTQYTF GSLGG*L*ILAHLS*KFLPRETCLGLLWCQWNG *VTWVGNLGS*PFSFGKC*RLKRMNMKLSKISRL KGTCVTEVGHCHFCFKSWGEYL**T*IKGTKLE LIHSFIHLWSCY*FCGGQVHTNGH*YNQCSQGC AGVGGHAVRMV*ASG*EPEKQDFFLLYHELCPFT MQAHDPRDSWFTGRSP*WTY*GKGEMNTAPKEG VKYDLTYARAYN*SQSRLYICLCSIHSAKTFGV CARHSFKHIM*F*KMNKLERF

Frame 2

QLRRLQTMGQGAYGARICQTEG*FISQAGWSRA VCYFIVLLRTYELFISGISHLIFLDCG*SRVNE IAESKNTDKGDCLLYKDRDKRKELSSRAFCVKT SGTQIRCMQVA*ENMHPGPEEAGSGRYGPRYITD MGAGEDDEGFEDDLDLDISFEEVKPLPATKGGN KKFLVESKKMSISNPKTISRLIPPTSASLPVTT VAPQPIPIQRKGKNGVAIMSRLFDMPCDETLCSA DSFCVNDYTWGGSRCQCTLGKGGESCSEDIVIQ YPQFFGHSYVTFEPLKNSYQAFQITLEFRAEAE DGLLLYCGENEHGRGDFMSLAIIRRSLQFRFNCG TGVAIIVSETKIKLGGWHTVMLYRDGLNGLLQL NNGTPVTGQSQGQYSKITFRTPLYLGGAPSAYW LVRATGTNRGFQGCVQSLAVNGRRIDMRPWPLGK ALSGADVGECSSGICDEASCIHGGTCTAIKADS YICLCPLGFKGRHCEDAFTLTIPQFRESLRSYA ATPWPLEPQHYLSFMEFEITFRPDSGDGVLLYSY DTGSKDFLSINLAGGHVEFRFDCGSGTGVLRSE DPLTLGNWHELRVSRTAKNGILQVDKQKIVEGM AEGGFTQIKCNTDIFIGGVPNYDDVKKNSGVLKP FSGSIQKIILNDRTIHVKHDFTSGVNVENAAHP CVRAPCAHGGSCRPRKEGYDCDCPLGFEGLHCQ KAIIEAIEIPQFIGRSYLTYDNPDILKRVSGSRS NVFMRFKTTAKDGLLLWRGDSPMRPNSDFISLG LRDGALVFSYNLGSGVASIMVNGSFNDGRWHRV KAVRDGQSGKITVDDYGARTGKSPGMMRQLNING ALYVGGMKEIALHTNRQYMRGLVGCISHFTLST DYHISLVEDAVDGKNINTCGAK*HQLALSKGQS LLF*ESQGPSDPA*CYMQRPRDQVCFLSPRRKYT LMRN*EPRQASLGGLSC*HSTS*PSRILCVGSI GLCPLNM*RLPEITHQCKFQSLSAIAQ*LCCDS *YIKKREREKESHRALLKYFSPSLTHDTLPDSRM TV*P*TSHFPHWPLDCSD*PLPLLTGWFTVF*L VHKNKDGRRSNTES*S*CGPLPQSLPRM*NPYF L*CRVKELSPHDFVAVLLYVYIFIAADCPHSILL EVWVDDSEFLHTFPKNFSQERLVWAFCGVSGMD R*LGWATWGADHSLLVNVDGSRG*I*SFPR*AD *KEHVLPR*VTVIFVLRVGGSIYSKLE*RGQS*N LFIHSFTYGVVTDFAEVRFIPMDTNTISVPKAV QGWGDMLSGWSEHLGENQRNRTSSFCTMSCVPL LCKHMTPETAGSLADPHDGLTKGKVR*TLPPRRG *NMI*LMQEPIISPSLDSTFVCAAFIQQRLLGF VQGTVLST*CNSKR*IN*RG

Sequence NM_152403

ACTCGATTGTAATTTCATCCCCGGGCCGGTCGAGCCTCCCTCCCTCCCGCGGCCAGCCCTTCCCTCCCAGTCGGCCTCCTTCGTCGCCCCCGCCCCCGCG AAAAGCCCTGCAGCTTGCAGCCGGCTTCACTCGCGCACGCCGACCTCCCGGCTGCAGTCCTACCTCTTGGAACTACCCGTGTTTCCGGGCCCAGCCCTCG CAGCCCCCCACCTCCTCGCCCCGGCCCGGGGATCCGTTGGGGCCGCGTCCCCCACGCGCCCCCGGAGACGCCCTTTCCGTGTGCGCCCGGGACTTGGTGA AACTTTGCAGGCGCCGGCTGCGAAATGGATTTAATCCGAGGCGTCTTGCTCCGGCTCCTGCTCCTGGCTTCCAGCCTCGGACCCGGCGCGGTGTCGCTCC GAGCGGCCATCCGAAAACCAGGCAAGGTAGGGCCTCCTCTTGACATCAAGCTGGGCGCATTGAACTGTACGGCTTTCAGCATCCAGTGGAAAATGCCAAG GCATCCTGGAAGTCCCATCCTTGGGTACACTGTCTTTTACTCTGAGGTTGGCGCAGATAAATCCCTGCAGGAGCAGTTGCACAGCGTGCCTCTCAGCCGG GACATCCCGACCACGGAGGAAGTGATTGGAGATTTGAAACCAGGCACTGAATATCGTGTGAGCATAGCAGCTTACAGCCAGGCTGGCAAAGGGCGGCTGA GCTCTCCTCGGCATGTCACCACTTTGTCCCAAGATTCCTGCCTGCCTCCTGCAGCTCCCCAGCAGCCACATGTCATTGTGGTTTCGGATTCTGAGGTGGC CCTGTCTTGGAAACCTGGAGCGAGTGAAGGAAGCGCCCCTATTCAGTACTATTCTGTGGAATTCATCAGGCCAGATTTCGACAAGAAGTGGACCTCAATC CATGAGCGGATCCAGATGGACTCCATGGTTATCAAGGGCCTCGATCCAGATACCAACTACCAGTTTGCCGTGAGGGCAATGAATTCCCATGGCCCCAGCC CCCGCAGCTGGCCCAGTGACATCATCCGGACCCTCTGCCCTGAGGAGGCGGGAAGTGGCCGCTATGGACCCCGTTATATCACCGACATGGGAGCTGGTGA GGATGATGAAGGATTTGAAGACGACTTAGATTTGGATATTTCCTTTGAGGAGGTTAAACCACTTCCTGCTACCAAAGGAGGGAATAAGAAATTTTTGGTG GAAAGCAAGAAGATGTCTATATCTAACCCAAAGACCATTTCTAGGCTCATCCCCCCTACCTCAGCATCTCTCCCTGTGACCACGGTGGCTCCCCAGCCCA TTCCCATACAGAGAAAGGGGAAGAATGGTGTGGCCATAATGTCAAGGCTCTTTGACATGCCTTGTGATGAAACTCTCTGCTCTGCTGACAGCTTCTGTGT CAATGACTACACCTGGGGGGGCTCGCGATGCCAGTGCACCCTGGGCAAAGGTGGTGAGAGCTGCTCAGAAGATATTGTTATCCAGTATCCTCAGTTCTTT GGCCACTCCTATGTAACGTTTGAACCTCTGAAGAATTCTTATCAGGCATTTCAAATTACTCTTGAATTTAGGGCGGAGGCAGAGGATGGCTTACTGCTCT ACTGTGGGGAGAACGAACACGGGAGGGGGGATTTCATGTCCCTGGCTATCATCCGACGCTCCCTGCAGTTCAGGTTTAATTGTGGAACTGGGGTTGCCAT CATCGTAAGTGAGACCAAAATCAAACTAGGGGGTTGGCACACGGTTATGCTCTACAGAGATGGGCTGAACGGGCTGCTGCAGCTGAACAATGGCACCCCA GTGACAGGCCAGTCTCAGGGCCAATACAGTAAAATTACTTTCCGGACACCTCTCTATCTTGGTGGCGCTCCCAGCGCTTACTGGTTGGTTAGAGCAACAG GGACAAACCGAGGCTTTCAAGGCTGTGTGCAGTCGCTCGCTGTGAATGGGAGGAGAATTGACATGAGGCCCTGGCCCCTGGGAAAAGCACTCAGTGGGGC TGATGTGGGGGAATGCAGCAGTGGAATCTGTGATGAGGCCTCGTGCATCCATGGTGGCACCTGCACAGCAATCAAAGCCGACTCCTACATTTGCCTCTGT CCCCTTGGGTTTAAAGGTCGACACTGTGAAGATGCTTTCACCTTGACCATTCCTCAGTTCAGAGAGTCTCTGAGATCTTACGCTGCAACTCCCTGGCCAC TGGAGCCCCAGCATTACCTTTCCTTCATGGAATTTGAGATCACATTTCGGCCAGACTCAGGAGATGGTGTCCTCCTGTACAGCTATGACACAGGCAGCAA AGACTTCCTGTCCATCAACTTGGCAGGGGGCCACGTGGAGTTCCGCTTTGACTGTGGCTCTGGGACCGGTGTCCTCAGGAGTGAAGATCCCCTCACCCTG GGCAACTGGCACGAGCTTCGTGTATCTCGCACAGCAAAGAATGGAATCTTACAGGTGGATAAGCAGAAGATAGTGGAGGGAATGGCAGAGGGAGGCTTCA CACAGATTAAGTGCAACACAGACATTTTCATTGGCGGAGTCCCCAATTATGATGATGTGAAGAAGAACTCGGGTGTCCTGAAGCCTTTCAGCGGGAGCAT CCAGAAGATCATCCTGAATGACCGAACCATCCATGTGAAGCATGACTTCACCTCCGGAGTGAATGTGGAGAATGCGGCCCACCCCTGTGTGAGAGCCCCT TGTGCCCATGGGGGCAGCTGCCGGCCCAGGAAGGAGGGCTATGACTGTGACTGCCCCTTGGGCTTTGAGGGGCTTCACTGCCAGAAAGCGATCATAGAAG CCATTGAGATCCCGCAGTTTATCGGCCGCAGTTACCTGACGTATGACAACCCAGATATCTTGAAGAGGGTGTCAGGATCAAGATCAAATGTGTTCATGAG GTTTAAAACAACTGCCAAGGATGGCCTTTTGCTGTGGAGGGGAGACAGCCCCATGAGACCCAACAGCGACTTCATTTCCTTGGGCCTTCGGGATGGAGCC CTCGTGTTCAGCTATAACCTGGGCAGTGGTGTGGCATCCATCATGGTGAATGGCTCCTTCAACGATGGTCGGTGGCACCGAGTTAAGGCCGTTAGGGATG GCCAGTCAGGAAAGATAACCGTGGATGACTATGGAGCCAGAACAGGCAAATCCCCAGGCATGATGCGGCAGCTTAACATCAATGGAGCTCTGTATGTGGG TGGAATGAAGGAAATTGCTCTGCACACTAACAGGCAATATATGAGAGGGCTCGTGGGCTGTATCTCTCACTTCACCCTGTCCACCGATTACCACATTTCC CTCGTGGAAGATGCCGTGGATGGGAAAAACATCAACACTTGTGGAGCCAAGTAACACCAGCTGGCCTTGTCCAAGGGACAGAGCCTTCTATTCTGAGAAT CCCAGGGGCCCTCAGACCCTGCCTGATGCTATATGCAGAGGCCCAGGGACCAGGTGTGTTTCCTCTCACCAAGAAGAAAGTACACACTGATGAGAAACTG AGAACCAAGACAGGCATCCCTGGGTGGCCTTTCCTGCTGACACTCCACGAGCTGACCCAGCAGAATTCTCTGTGTAGGAAGCATCGGACTTTGTCCATTG AATATGTAGCGGCTGCCAGAGATCACACATCAATGCAAATTCCAGAGCCTGTCTGCTATAGCTCAGTGACTGTGTTGTGATTCATAGTACATTAAAAAGA GAGAGAGAGAGAAAGAATCCCACAGGGCACTATTAAAATACTTCTCTCCTTCCCTGACTCATGACACTCTTCCTGACAGCAGAATGACTGTGTGACCTTG AACTTCACATTTCCCACATTGGCCCTTGGATTGTTCGGATTAACCCCTTCCACTCCTCACTGGCTGGTTCACTGTGTTCTGACTAGTCCATAAAAATAAA GATGGAAGGAGATCAAACACAGAATCATAATCATAATGCGGCCCCCTTCCCCAGAGCTTACCTCGAATGTGAAATCCCTACTTCTTATAATGCAGAGTTA AGGAGCTGAGCCCCCATGATTTTGTAGCTGTACTTTTGTATGTGTATATTTTTATAGCTGCAGATTGTCCACACAGTATACTTTTGGAAGTTTGGGTGGA TGACTCTGAATTCTTGCACACCTTTCCTAAAAATTTCTCCCAAGAGAGACTTGTTTGGGCCTTTTGTGGTGTCAGTGGAATGGATAGGTAACTTGGGTGG GCAACTTGGGGAGCTGACCATTCTCTTTTGGTAAATGTTGACGGCTCAAGAGGATGAATATGAAGCTTTCCAAGATAAGCAGATTAAAAGGAACATGTGT TACCGAGGTAGGTCACTGTCATTTTTGTTTTAAGAGTTGGGGGGAGTATCTATAGTAAACTTGAATAAAGGGGACAAAGCTAGAACTTATTCATTCATTC ATTCACTTATGGAGTTGTTACTGATTTTGCGGAGGTCAGGTTCATACCAATGGACACTAATACAATCAGTGTTCCCAAGGCTGTGCAGGGGTGGGGGGAC ATGCTGTCAGGATGGTCTGAGCATCTGGGTGAGAACCAGAGAAACAGGACTTCTTCCTTCTGTACCATGAGCTGTGTCCCTTTACTATGCAAGCACATGA CCCCAGAGACAGCTGGTTCACTGGCAGATCCCCATGATGGACTTACTAAGGGAAAGGTGAGATGAACACTGCCCCCAAGGAGGGGGTGAAATATGATCTA ACTTATGCAAGAGCCTATAATTAGTCCCAGTCTCGACTCTACATTTGTTTGTGCAGCATTCATTCAGCAAAGACTTTTGGGGTTTGTGCAAGGCACAGTT TTAAGCACATAATGTAATTCTAAAAGATGAATAAACTAGAGAGGTTC

refseq_EGFLAM.F1 (forward primer)
refseq_EGFLAM.R1 (reverse primer)
Single exon skipping

Frame 0

TRL*FHPRAGRASLPPAASPSLPVGLLRRPRPR EKPCSLQPASLAHADLPAAVLPLGTTRVSGPSPR SPPPPRPGPGIRWGRVPHAPPETPFPCAPGTW* NFAGAGCEMDLIRGVLLRLLLLASSLGPGAVSL RAAIRKPGKVGPPLDIKLGALNCTAFSIQWKMPR HPGSPILGYTVFYSEVGADKSLQEQLHSVPLSR DIPTTEEVIGDLKPGTEYRVSIAAYSQAGKGRL SSPRHVTTLSQDSCLPPAAPQQPHVIVVSDSEVA LSWKPGASEGSAPIQYYSVEFIRPDFDKKWTSI HERIQMDSMVIKGLDPDTNYQFAVRAMNSHGPS PRSWPSDIIRTLCPEEAGSGRYGPRYITDMGAGE DDEGFEDDLDLDISFEEVKPLPATKGGNKKFLV ESKKMSISNPKTISRLIPPTSASLPVTTVAPQP IPIQRKGKNGVAIMSRLFDMPCDETLCSADSFCV NDYTWGGSRCQCTLGKGGESCSEDIVIQYPQFF GHSYVTFEPLKNSYQAFQITLEFRAEAEDGLLL YCGENEHGRGDFMSLAIIRRSLQFRFNCGTGVAI IVSETKIKLGGWHTVMLYRDGLNGLLQLNNGTP VTGQSQGQYSKITFRTPLYLGGAPSAYWLVRAT GTNRGFQGCVQSLAVNGRRIDMRPWPLGKALSGA DVGECSSGICDEASCIHGGTCTAIKADSYICLC PLGFKGRHCEDAFTLTIPQFRESLRSYAATPWP LEPQHYLSFMEFEITFRPDSGDGVLLYSYDTGSK DFLSINLAGGHVEFRFDCGSGTGVLRSEDPLTL GNWHELRVSRTAKNGILQVDKQKIVEGMAEGGF TQIKCNTDIFIGGVPNYDDVKKNSGVLKPFSGSI QKIILNDRTIHVKHDFTSGVNVENAAHPCVRAP CAHGGSCRPRKEGYDCDCPLGFEGLHCQKAIIE AIEIPQFIGRSYLTYDNPDILKRVSGSRSNVFMR FKTTAKDGLLLWRGDSPMRPNSDFISLGLRDGA LVFSYNLGSGVASIMVNGSFNDGRWHRVKAVRD GQSGKITVDDYGARTGKSPGMMRQLNINGALYVG GMKEIALHTNRQYMRGLVGCISHFTLSTDYHIS LVEDAVDGKNINTCGAK*HQLALSKGQSLLF*E SQGPSDPA*CYMQRPRDQVCFLSPRRKYTLMRN* EPRQASLGGLSC*HSTS*PSRILCVGSIGLCPL NM*RLPEITHQCKFQSLSAIAQ*LCCDS*YIKK REREKESHRALLKYFSPSLTHDTLPDSRMTV*P* TSHFPHWPLDCSD*PLPLLTGWFTVF*LVHKNK DGRRSNTES*S*CGPLPQSLPRM*NPYFL*CRV KELSPHDFVAVLLYVYIFIAADCPHSILLEVWVD DSEFLHTFPKNFSQERLVWAFCGVSGMDR*LGW ATWGADHSLLVNVDGSRG*I*SFPR*AD*KEHV LPR*VTVIFVLRVGGSIYSKLE*RGQS*NLFIHS FTYGVVTDFAEVRFIPMDTNTISVPKAVQGWGD MLSGWSEHLGENQRNRTSSFCTMSCVPLLCKHM TPETAGSLADPHDGLTKGKVR*TLPPRRG*NMI* LMQEPIISPSLDSTFVCAAFIQQRLLGFVQGTV LST*CNSKR*IN*RG

Frame 1

LDCNFIPGPVEPPSLPRPALPSQSASFVAPAPA KSPAACSRLHSRTPTSRLQSYLLELPVFPGPAL AAPHLLAPARGSVGAASPTRPRRRPFRVRPGLGE TLQAPAAKWI*SEASCSGSCSWLPASDPARCRS ERPSENQAR*GLLLTSSWAH*TVRLSASSGKCQ GILEVPSLGTLSFTLRLAQINPCRSSCTACLSAG TSRPRRK*LEI*NQALNIV*A*QLTARLAKGG* ALLGMSPLCPKIPACLLQLPSSHMSLWFRILRW PCLGNLERVKEAPLFSTILWNSSGQISTRSGPQS MSGSRWTPWLSRASIQIPTTSLP*GQ*IPMAPA PAAGPVTSSGPSALRRREVAAMDPVISPTWELV RMMKDLKTT*IWIFPLRRLNHFLLPKEGIRNFWW KARRCLYLTQRPFLGSSPLPQHLSL*PRWLPSP FPYRERGRMVWP*CQGSLTCLVMKLSALLTASV SMTTPGGARDASAPWAKVVRAAQKILLSSILSSL ATPM*RLNL*RILIRHFKLLLNLGRRQRMAYCS TVGRTNTGGGISCPWLSSDAPCSSGLIVELGLP SS*VRPKSN*GVGTRLCSTEMG*TGCCS*TMAPQ *QASLRANTVKLLSGHLSILVALPALTGWLEQQ GQTEAFKAVCSRSL*MGGELT*GPGPWEKHSVG LMWGNAAVESVMRPRASMVAPAQQSKPTPTFASV PLGLKVDTVKMLSP*PFLSSESL*DLTLQLPGH WSPSITFPSWNLRSHFGQTQEMVSSCTAMTQAA KTSCPSTWQGATWSSALTVALGPVSSGVKIPSPW ATGTSFVYLAQQRMESYRWISRR*WREWQREAS HRLSATQTFSLAESPIMMM*RRTRVS*SLSAGA SRRSS*MTEPSM*SMTSPPE*MWRMRPTPV*EPL VPMGAAAGPGRRAMTVTAPWALRGFTARKRS*K PLRSRSLSAAVT*RMTTQIS*RGCQDQDQMCS* GLKQLPRMAFCCGGETAP*DPTATSFPWAFGMEP SCSAITWAVVWHPSW*MAPSTMVGGTELRPLGM ASQER*PWMTMEPEQANPQA*CGSLTSMELCMW VE*RKLLCTLTGNI*EGSWAVSLTSPCPPITTFP SWKMPWMGKTSTLVEPSNTSWPCPRDRAFYSEN PRGPQTLPDAICRGPGTRCVSSHQEESTH**ET ENQDRHPWVAFPADTPRADPAEFSV*EASDFVH* ICSGCQRSHINANSRACLL*LSDCVVIHSTLKR ERERKNPTGHY*NTSLLP*LMTLFLTAE*LCDL ELHISHIGPWIVRINPFHSSLAGSLCSD*SIKIK MEGDQTQNHNHNAAPFPRAYLECEIPTSYNAEL RS*APMIL*LYFCMCIFL*LQIVHTVYFWKFGW MTLNSCTPFLKISPKRDLFGPFVVSVEWIGNLGG QLGELTILFW*MLTAQEDEYEAFQDKQIKRNMC YRGRSLSFLF*ELGGVSIVNLNKGDKARTYSFI HSLMELLLILRRSGSYQWTLIQSVFPRLCRGGGT CCQDGLSIWVRTRETGLLPSVP*AVSLYYAST* PQRQLVHWQIPMMDLLRER*DEHCPQGGGEI*S NLCKSL*LVPVSTLHLFVQHSFSKDFWGLCKAQF *AHNVILKDE*TREV

Frame 2

SIVISSPGRSSLPPSRGQPFPPSRPPSSPPPPR KALQLAAGFTRARRPPGCSPTSWNYPCFRAQPS QPPTSSPRPGDPLGPRPPRAPGDALSVCARDLV KLCRRRLRNGFNPRRLAPAPAPGFQPRTRRGVAP SGHPKTRQGRASS*HQAGRIELYGFQHPVENAK ASWKSHPWVHCLLL*GWRR*IPAGAVAQRASQP GHPDHGGSDWRFETRH*ISCEHSSLQPGWQRAAE LSSACHHFVPRFLPASCSSPAATCHCGFGF*GG PVLETWSE*RKRPYSVLFCGIHQARFRQEVDLN P*ADPDGLHGYQGPRSRYQLPVCREGNEFPWPQP PQLAQ*HHPDPLP*GGGKWPLWTPLYHRHGSW* G**RI*RRLRFGYFL*GG*TTSCYQRRE*EIFG GKQEDVYI*PKDHF*AHPPYLSISPCDHGGSPAH SHTEKGEEWCGHNVKAL*HAL**NSLLC*QLLC Q*LHLGGLAMPVHPGQRW*ELLRRYCYPVSSVL WPLLCNV*TSEEFLSGISNYS*I*GGGRGWLTAL LWGERTREGGFHVPGYHPTLPAVQV*LWNWGCH HRK*DQNQTRGLAHGYALQRWAERAAAAEQWHP SDRPVSGPIQ*NYFPDTSLSWWRSQRLLVG*SNR DKPRLSRLCAVARCEWEEN*HEALAPGKSTQWG *CGGMQQWNL**GLVHPWWHLHSNQSRLLHLPL SPWV*RSTL*RCFHLDHSSVQRVSEILRCNSLAT GAPALPFLHGI*DHISARLRRWCPPVQL*HRQQ RLPVHQLGRGPRGVPL*LWLWDRCPQE*RSPHP GQLARASCISHSKEWNLTGG*AEDSGGNGRGRLH TD*VQHRHFHWRSPQL**CEEELGCPEAFQREH PEDHPE*PNHPCEA*LHLRSECGECGPPLCESP LCPWGQLPAQEGGL*L*LPLGL*GASLPESDHRS H*DPAVYRPQLPDV*QPRYLEEGVRIKIKCVHE V*NNCQGWPFAVEGRQPHETQQRLHFLGPSGWS PRVQL*PGQWCGIHHGEWLLQRWSVAPS*GR*GW PVRKDNRG*LWSQNRQIPRHDAAA*HQWSSVCG WNEGNCSAH*QAIYERARGLYLSLHPVHRLPHF PRGRCRGWEKHQHLWSQVTPAGLVQGTEPSILRI PGALRPCLMLYAEAQGPGVFPLTKKKVHTDEKL RTKTGIPGWPFLLTLHELTQQNSLCRKHRTLSI EYVAAARDHTSMQIPEPVCYSSVTVL*FIVH*KE RERERIPQGTIKILLSFPDS*HSS*QQNDCVTL NFTFPTLALGLFGLTPSTPHWLVHCVLTSP*K* RWKEIKHRIIIIMRPPSPELTSNVKSLLLIMQS* GAEPP*FCSCTFVCVYFYSCRLSTQYTFGSLGG *L*ILAHLS*KFLPRETCLGLLWCQWNG*VTWV GNLGS*PFSFGKC*RLKRMNMKLSKISRLKGTCV TEVGHCHFCFKSWGEYL**T*IKGTKLELIHSF IHLWSCY*FCGGQVHTNGH*YNQCSQGCAGVGG HAVRMV*ASG*EPEKQDFFLLYHELCPFTMQAHD PRDSWFTGRSP*WTY*GKGEMNTAPKEGVKYDL TYARAYN*SQSRLYICLCSIHSAKTFGVCARHS FKHIM*F*KMNKLERF