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Sequences

Sequence NM_194429

CGGCCGCGTAGCCCGCGCGCGGAGCGTACCCTGCTGCGGCCGTTGGCCGTTAGCGCGGCTTCGGCGGTTGTCTTGGAGAAGCAAGATGGCGGCGACGGCG
GCCGCAGTGGTGGCCGAGGAGGACACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGGTCCTGAACCGCATCAAGGCTGAACTCCGAG
CAGCTGTGTTTTTAGCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTAATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCG
TTTAGTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACTTTACTTTGGCTGTTTTTCAACCTGAAACTAGCACACTGCAAGGTCTCGAA
GGTCGAGAGAATTTAGCCCGAGATTTAGGTATAATTGAAGCAGAAGGTACTGTGGGTGGACCCTTATTATTAGAAGTGATCAGGCGCTGTCAACAGAAAG
AAAAAGGGCCAACCACTGGGGAAGGTGCACTTGATCTATCTGATGTACATTCTCCACCAAAGTCACCAGAGGGAAAAACAAGTGCACAGACAACACCAAG
TAAGAAGGCCAATGATGAGGCCAATCAGAGTGATACAAGTGTCTCCTTGTCAGAACCCAAGAGCAAAAGCAGCCTTCACTTACTGTCCCATGAAACAAAA
ATTGGATCTTTTCTAAGCAACAGAACTTTAGATGGCAAAGACAAAGCTGGCCTTTGTCCAGATGAAGATGATATGGAAGGAGATTCTTTCTTTGATGATC
CCATTCCTAAGCCAGAGAAAACTTACGGTTTGAGGAAGGAACCTAGGAAGCAAGCAGGAAGTCTGGCCTCGCTCTCGGATGCACCCCCCTTAAAAAGTGG
ACTCAGCTCCCTGGCGGGAGCCCCTTCTTTAAAAGACTCTGAGAGTAAAAGGGGAAATACAGTTTTGAAAGATCTGAAATTGATCAGTGATAAAATTGGA
TCACTTGGATTAGGAACTGGAGAAGATGATGACTATGTTGATGATTTTAATAGTACCAGCCATCGCTCAGAGAAAAGTGAGATAAGTATTGGTGAAGAGA
TAGAAGAAGACCTTTCTGTGGAAATAGATGACATCAATACCAGTGATAAGCTTGATGACCTCACACAAGATCTGACTGTATCCCAGCTCAGTGATGTTGC
GGATTATCTGGAAGATGTTGCATAGACACGAAGAAGGAAGTATTCTAATTAACAAGGACAGAGGACTGACCGGTTCCATTTTTTTTTTTTCCAGACAATC
ACTCAGCTGGAATGTCTGCTCTCTATTGGTGCCTTGCATTTCAAAAACACTGCAGATATTTTTTAAAAGTAATTTTCATTTTACTAAACAAAATACTTCC
TATTTGAGCCCATGTGTGGAAGATTTAATATTCTTAATTTAACTGTACATTTCTTTATGGAAATTGATTATCTACACTCAGTTTCATTACAGGGAAGGAA
CCCATGAAAACATCAGTGTTAAGAGCATGATGAAAGGTGTCAATAAAGCCGTAGGATCGCGCAACCCTTTGTGTGTGTGGCTGCTGGTACGTGTGATCTT
TGAAAACCTTGGCTTTAGCCCTCTGGAATCAGAGCTTACCCACCATAGTATATTTTGATATTAGGTGGTTCTACACATAGTTGGCAAAATGACTTGGTAA
ATTTGTAATGCTGAAGTATATTAGTATAAGTTAAATTTGATGTGTCAACTTTATTTTGTATTTCCTTCCATTTGGAAGGTTTGTTAGACCATTAAGGTTA
TATTAAAGTACTCTTGTGTGTGCTA
  • refseq_FGFR1OP.F1 (forward primer)
  • refseq_FGFR1OP.R1 (reverse primer)
  • Single exon skipping

Frame 0

RPRSPRAERTLLRPLAVSAASAVVLEKQDGGDG
GRSGGRGGHGAAGPAGADAGEQRGPEPHQG*TPS
SCVFSTRGARKSREQNSFS**EPEKVFKYQRRS
FSG*SCCRISSVF*P*LYFGCFST*N*HTARSR
RSREFSPRFRYN*SRRYCGWTLIIRSDQALSTER
KRANHWGRCT*SI*CTFSTKVTRGKNKCTDNTK
*EGQ**GQSE*YKCLLVRTQEQKQPSLTVP*NK
NWIFSKQQNFRWQRQSWPLSR*R*YGRRFFL**S
HS*ARENLRFEEGT*EASRKSGLALGCTPLKKW
TQLPGGSPFFKRL*E*KGKYSFERSEIDQ**NW
ITWIRNWRR**LC**F**YQPSLREK*DKYW*RD
RRRPFCGNR*HQYQ**A**PHTRSDCIPAQ*CC
GLSGRCCIDTKKEVF*LTRTED*PVPFFFFPDN
HSAGMSALYWCLAFQKHCRYFLKVIFILLNKILP
I*AHVWKI*YS*FNCTFLYGN*LSTLSFITGKE
PMKTSVLRA**KVSIKP*DRATLCVCGCWYV*S
LKTLALALWNQSLPTIVYFDIRWFYT*LAK*LGK
FVMLKYISIS*I*CVNFILYFLPFGRFVRPLRL
Y*STLVCA

Frame 1

GRVARARSVPCCGRWPLARLRRLSWRSKMAATA
AAVVAEEDTELRDLLVQTLENSGVLNRIKAELR
AAVFLALEEQEKVENKTPLVNESLKKFLNTKDGR
LVASLVAEFLQFFNLDFTLAVFQPETSTLQGLE
GRENLARDLGIIEAEGTVGGPLLLEVIRRCQQK
EKGPTTGEGALDLSDVHSPPKSPEGKTSAQTTPS
KKANDEANQSDTSVSLSEPKSKSSLHLLSHETK
IGSFLSNRTLDGKDKAGLCPDEDDMEGDSFFDD
PIPKPEKTYGLRKEPRKQAGSLASLSDAPPLKSG
LSSLAGAPSLKDSESKRGNTVLKDLKLISDKIG
SLGLGTGEDDDYVDDFNSTSHRSEKSEISIGEE
IEEDLSVEIDDINTSDKLDDLTQDLTVSQLSDVA
DYLEDVA*TRRRKYSN*QGQRTDRFHFFFFQTI
TQLECLLSIGALHFKNTADIF*K*FSFY*TKYF
LFEPMCGRFNILNLTVHFFMEIDYLHSVSLQGRN
P*KHQC*EHDERCQ*SRRIAQPFVCVAAGTCDL
*KPWL*PSGIRAYPP*YILILGGSTHSWQNDLV
NL*C*SILV*VKFDVSTLFCISFHLEGLLDH*GY
IKVLLCVL

Frame 2

AA*PARGAYPAAAVGR*RGFGGCLGEARWRRRR
PQWWPRRTRSCGTCWCRRWRTAGS*TASRLNSE
QLCF*H*RSKKK*RTKLL*LMRA*KSF*IPKTV
V*WLVLLQNFFSFLTLTLLWLFFNLKLAHCKVSK
VERI*PEI*V*LKQKVLWVDPYY*K*SGAVNRK
KKGQPLGKVHLIYLMYILHQSHQREKQVHRQHQ
VRRPMMRPIRVIQVSPCQNPRAKAAFTYCPMKQK
LDLF*ATEL*MAKTKLAFVQMKMIWKEILSLMI
PFLSQRKLTV*GRNLGSKQEVWPRSRMHPP*KV
DSAPWREPLL*KTLRVKGEIQF*KI*N*SVIKLD
HLD*ELEKMMTMLMILIVPAIAQRKVR*VLVKR
*KKTFLWK*MTSIPVISLMTSHKI*LYPSSVML
RIIWKMLHRHEEGSILINKDRGLTGSIFFFSRQS
LSWNVCSLLVPCISKTLQIFFKSNFHFTKQNTS
YLSPCVEDLIFLI*LYISLWKLIIYTQFHYREG
THENISVKSMMKGVNKAVGSRNPLCVWLLVRVIF
ENLGFSPLESELTHHSIF*Y*VVLHIVGKMTW*
ICNAEVY*YKLNLMCQLYFVFPSIWKVC*TIKV
ILKYSCVC

Sequence NM_007045

CGGCCGCGTAGCCCGCGCGCGGAGCGTACCCTGCTGCGGCCGTTGGCCGTTAGCGCGGCTTCGGCGGTTGTCTTGGAGAAGCAAGATGGCGGCGACGGCG
GCCGCAGTGGTGGCCGAGGAGGACACGGAGCTGCGGGACCTGCTGGTGCAGACGCTGGAGAACAGCGGGGTCCTGAACCGCATCAAGGCTGAACTCCGAG
CAGCTGTGTTTTTAGCACTAGAGGAGCAAGAAAAAGTAGAGAACAAAACTCCTTTAGTTAATGAGAGCCTGAAAAAGTTTTTAAATACCAAAGACGGTCG
TTTAGTGGCTAGTCTTGTTGCAGAATTTCTTCAGTTTTTTAACCTTGACTTTACTTTGGCTGTTTTTCAACCTGAAACTAGCACACTGCAAGGTCTCGAA
GGTCGAGAGAATTTAGCCCGAGATTTAGGTATAATTGAAGCAGAAGGTACTGTGGGTGGACCCTTATTATTAGAAGTGATCAGGCGCTGTCAACAGAAAG
AAAAAGGGCCAACCACTGGGGAAGGTGCACTTGATCTATCTGATGTACATTCTCCACCAAAGTCACCAGAGGGAAAAACAAGTGCACAGACAACACCAAG
TAAGATACCAAGGTATAAAGGACAAGGTAAGAAGAAGACAAGCGGGCAGAAGGCTGGTGACAAGAAGGCCAATGATGAGGCCAATCAGAGTGATACAAGT
GTC
TCCTTGTCAGAACCCAAGAGCAAAAGCAGCCTTCACTTACTGTCCCATGAAACAAAAATTGGATCTTTTCTAAGCAACAGAACTTTAGATGGCAAAG
ACAAAGCTGGCCTTTGTCCAGATGAAGATGATATGGAAGGAGATTCTTTCTTTGATGATCCCATTCCTAAGCCAGAGAAAACTTACGGTTTGAGGAAGGA
ACCTAGGAAGCAAGCAGGAAGTCTGGCCTCGCTCTCGGATGCACCCCCCTTAAAAAGTGGACTCAGCTCCCTGGCGGGAGCCCCTTCTTTAAAAGACTCT
GAGAGTAAAAGGGGAAATACAGTTTTGAAAGATCTGAAATTGATCAGTGATAAAATTGGATCACTTGGATTAGGAACTGGAGAAGATGATGACTATGTTG
ATGATTTTAATAGTACCAGCCATCGCTCAGAGAAAAGTGAGATAAGTATTGGTGAAGAGATAGAAGAAGACCTTTCTGTGGAAATAGATGACATCAATAC
CAGTGATAAGCTTGATGACCTCACACAAGATCTGACTGTATCCCAGCTCAGTGATGTTGCGGATTATCTGGAAGATGTTGCATAGACACGAAGAAGGAAG
TATTCTAATTAACAAGGACAGAGGACTGACCGGTTCCATTTTTTTTTTTTCCAGACAATCACTCAGCTGGAATGTCTGCTCTCTATTGGTGCCTTGCATT
TCAAAAACACTGCAGATATTTTTTAAAAGTAATTTTCATTTTACTAAACAAAATACTTCCTATTTGAGCCCATGTGTGGAAGATTTAATATTCTTAATTT
AACTGTACATTTCTTTATGGAAATTGATTATCTACACTCAGTTTCATTACAGGGAAGGAACCCATGAAAACATCAGTGTTAAGAGCATGATGAAAGGTGT
CAATAAAGCCGTAGGATCGCGCAACCCTTTGTGTGTGTGGCTGCTGGTACGTGTGATCTTTGAAAACCTTGGCTTTAGCCCTCTGGAATCAGAGCTTACC
CACCATAGTATATTTTGATATTAGGTGGTTCTACACATAGTTGGCAAAATGACTTGGTAAATTTGTAATGCTGAAGTATATTAGTATAAGTTAAATTTGA
TGTGTCAACTTTATTTTGTATTTCCTTCCATTTGGAAGGTTTGTTAGACCATTAAGGTTATATTAAAGTACTCTTGTGTGTGCTA
  • refseq_FGFR1OP.F1 (forward primer)
  • refseq_FGFR1OP.R1 (reverse primer)
  • Single exon skipping

Frame 0

RPRSPRAERTLLRPLAVSAASAVVLEKQDGGDG
GRSGGRGGHGAAGPAGADAGEQRGPEPHQG*TPS
SCVFSTRGARKSREQNSFS**EPEKVFKYQRRS
FSG*SCCRISSVF*P*LYFGCFST*N*HTARSR
RSREFSPRFRYN*SRRYCGWTLIIRSDQALSTER
KRANHWGRCT*SI*CTFSTKVTRGKNKCTDNTK
*DTKV*RTR*EEDKRAEGW*QEGQ**GQSE*YK
C
LLVRTQEQKQPSLTVP*NKNWIFSKQQNFRWQR
QSWPLSR*R*YGRRFFL**SHS*ARENLRFEEG
T*EASRKSGLALGCTPLKKWTQLPGGSPFFKRL
*E*KGKYSFERSEIDQ**NWITWIRNWRR**LC*
*F**YQPSLREK*DKYW*RDRRRPFCGNR*HQY
Q**A**PHTRSDCIPAQ*CCGLSGRCCIDTKKE
VF*LTRTED*PVPFFFFPDNHSAGMSALYWCLAF
QKHCRYFLKVIFILLNKILPI*AHVWKI*YS*F
NCTFLYGN*LSTLSFITGKEPMKTSVLRA**KV
SIKP*DRATLCVCGCWYV*SLKTLALALWNQSLP
TIVYFDIRWFYT*LAK*LGKFVMLKYISIS*I*
CVNFILYFLPFGRFVRPLRLY*STLVCA

Frame 1

GRVARARSVPCCGRWPLARLRRLSWRSKMAATA
AAVVAEEDTELRDLLVQTLENSGVLNRIKAELR
AAVFLALEEQEKVENKTPLVNESLKKFLNTKDGR
LVASLVAEFLQFFNLDFTLAVFQPETSTLQGLE
GRENLARDLGIIEAEGTVGGPLLLEVIRRCQQK
EKGPTTGEGALDLSDVHSPPKSPEGKTSAQTTPS
KIPRYKGQGKKKTSGQKAGDKKANDEANQSDTS
V
SLSEPKSKSSLHLLSHETKIGSFLSNRTLDGK
DKAGLCPDEDDMEGDSFFDDPIPKPEKTYGLRKE
PRKQAGSLASLSDAPPLKSGLSSLAGAPSLKDS
ESKRGNTVLKDLKLISDKIGSLGLGTGEDDDYV
DDFNSTSHRSEKSEISIGEEIEEDLSVEIDDINT
SDKLDDLTQDLTVSQLSDVADYLEDVA*TRRRK
YSN*QGQRTDRFHFFFFQTITQLECLLSIGALH
FKNTADIF*K*FSFY*TKYFLFEPMCGRFNILNL
TVHFFMEIDYLHSVSLQGRNP*KHQC*EHDERC
Q*SRRIAQPFVCVAAGTCDL*KPWL*PSGIRAY
PP*YILILGGSTHSWQNDLVNL*C*SILV*VKFD
VSTLFCISFHLEGLLDH*GYIKVLLCVL

Frame 2

AA*PARGAYPAAAVGR*RGFGGCLGEARWRRRR
PQWWPRRTRSCGTCWCRRWRTAGS*TASRLNSE
QLCF*H*RSKKK*RTKLL*LMRA*KSF*IPKTV
V*WLVLLQNFFSFLTLTLLWLFFNLKLAHCKVSK
VERI*PEI*V*LKQKVLWVDPYY*K*SGAVNRK
KKGQPLGKVHLIYLMYILHQSHQREKQVHRQHQ
VRYQGIKDKVRRRQAGRRLVTRRPMMRPIRVIQV
S
PCQNPRAKAAFTYCPMKQKLDLF*ATEL*MAK
TKLAFVQMKMIWKEILSLMIPFLSQRKLTV*GR
NLGSKQEVWPRSRMHPP*KVDSAPWREPLL*KTL
RVKGEIQF*KI*N*SVIKLDHLD*ELEKMMTML
MILIVPAIAQRKVR*VLVKR*KKTFLWK*MTSI
PVISLMTSHKI*LYPSSVMLRIIWKMLHRHEEGS
ILINKDRGLTGSIFFFSRQSLSWNVCSLLVPCI
SKTLQIFFKSNFHFTKQNTSYLSPCVEDLIFLI
*LYISLWKLIIYTQFHYREGTHENISVKSMMKGV
NKAVGSRNPLCVWLLVRVIFENLGFSPLESELT
HHSIF*Y*VVLHIVGKMTW*ICNAEVY*YKLNL
MCQLYFVFPSIWKVC*TIKVILKYSCVC

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