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Sequences

Sequence NM_001039349

GGACTTCGCCAGATCAGACCCACGGGGCTGCCCTCCCCTGCGCACTCCCCTCGCTGCCCGGGCCCGGAGCGCAGCGCGGCCGCACAGATTCACAATGTTG
AAAGCCCTTTTCCTAACTATGCTGACTCTGGCGCTGGTCAAGTCACAGGACACCGAAGAAACCATCACGTACACGCAATGCACTGACGGATATGAGTGGG
ATCCTGTGAGACAGCAATGCAAAGATATTGATGAATGTGACATTGTCCCAGACGCTTGTAAAGGTGGAATGAAGTGTGTCAACCACTATGGAGGATACCT
CTGCCTTCCGAAAACAGCCCAGATTATTGTCAATAATGAACAGCCTCAGCAGGAAACACAACCAGCAGAAGGAACCTCAGGGGCAACCACCGGGGTTGTA
GCTGCCAGCAGCATGGCAACCAGTGGAGTGTTGCCCGGGGGTGGTTTTGTGGCCAGTGCTGCTGCAGTCGCAGGCCCTGAAATGCAGACTGGCCGAAATA
ACTTTGTCATCCGGCGGAACCCAGCTGACCCTCAGCGCATTCCCTCCAACCCTTCCCACCGTATCCAGTGTGCAGCAGGCTACGAGCAAAGTGAACACAA
CGTGTGCCAAGACATAGACGAGTGCACTGCAGGGACGCACAACTGTAGAGCAGACCAAGTGTGCATCAATTTACGGGGATCCTTTGCATGTCAGTGCCCT
CCTGGATATCAGAAGCGAGGGGAGCAGTGCGTAGACATAGATGAATGTACCATCCCTCCATATTGCCACCAAAGATGCGTGAATACACCAGGCTCATTTT
ATTGCCAGTGCAGTCCTGGGTTTCAATTGGCAGCAAACAACTATACCTGCGTAGATATAAATGAATGTGATGCCAGCAATCAATGTGCTCAGCAGTGCTA
CAACATTCTTGGTTCATTCATCTGTCAGTGCAATCAAGGATATGAGCTAAGCAGTGACAGGCTCAACTGTGAAGACATTGATGAATGCAGAACCTCAAGC
TACCTGTGTCAATATCAATGTGTCAATGAACCTGGGAAATTCTCATGTATGTGCCCCCAGGGATACCAAGTGGTGAGAAGTAGAACATGTCAAGATATAA
ATGAGTGTGAGACCACAAATGAATGCCGGGAGGATGAAATGTGTTGGAATTATCATGGCGGCTTCCGTTGTTATCCACGAAATCCTTGTCAAGATCCCTA
CATTCTAACACCAGAGAACCGATGTGTTTGCCCAGTCTCAAATGCCATGTGCCGAGAACTGCCCCAGTCAATAGTCTACAAATACATGAGCATCCGATCT
GATAGGTCTGTGCCATCAGACATCTTCCAGATACAGGCCACAACTATTTATGCCAACACCATCAATACTTTTCGGATTAAATCTGGAAATGAAAATGGAG
AGTTCTACCTACGACAAACAAGTCCTGTAAGTGCAATGCTTGTGCTCGTGAAGTCATTATCAGGACCAAGAGAACATATCGTGGACCTGGAGATGCTGAC
AGTCAGCAGTATAGGGACCTTCCGCACAAGCTCTGTGTTAAGATTGACAATAATAGTGGGGCCATTTTCATTTTAGTCTTTTCTAAGAGTCAACCACAGG
CATTTAAGTCAGCCAAAGAATATTGTTACCTTAAAGCACTATTTTATTTATAGATATATCTAGTGCATCTACATCTCTATACTGTACACTCACCCATAAT
TCAAACAATTACACCATGGTATAAAGTGGGCATTTAATATGTAAAGATTCAAAGTTTGTCTTTATTACTATATGTAAATTAGACATTAATCCACTAAACT
GGTCTTCTTCAAGAGAGCTAAGTATACACTATCTGGTGAAACTTGGATTCTTTCCTATAAAAGTGGGACCAAGCAATGATGATCTTCTGTGGTGCTTAAG
GAAACTTACTAGAGCTCCACTAACAGTCTCATAAGGAGGCAGCCATCATAACCATTGAATAGCATGCAAGGGTAAGAATGAGTTTTTAACTGCTTTGTAA
GAAAATGGAAAAGGTCAATAAAGATATATTTCTTTAGAAAATGGGGATCTGCCATATTTGTGTTGGTTTTTATTTTCATATCCAGCCTAAAGGTGGTTGT
TTATTATATAGTAATAAATCATTGCTGTACAATATGCTGGTTTCTGTAGGGTATTTTTAATTTTGTCAGAAATTTTAGATTGTGAATATTTTGTAAAAAA
CAGTAAGCAAAATTTTCCAGAATTCCCAAAATGAACCAGATATCCCCTAGAAAATTATACTATTGAGAAATCTATGGGGAGGATATGAGAAAATAAATTC
CTTCTAAACCACATTGGAACTGACCTGAAGAAGCAAACTCGGAAAATATAATAACATCCCTGAATTCAGGACTTCCACAAGATGCAGAACAAAATGGATA
AAAGGTATTTCACTGGAGAAGTTTTAATTTCTAAGTAAAATTTAAATCCTAACACTTCACTAATTTATAACTAAAATTTCTCATCTTCGTACTTGATGCT
CACAGAGGAAGAAAATGATGATGGTTTTTATTCCTGGCATCCAGAGTGACAGTGAACTTAAGCAAATTACCCTCCTACCCAATTCTATGGAATATTTTAT
ACGTCTCCTTGTTTAAAATGTCACTGCTTTACTTTGATGTATCATATTTTTAAATAAAAATAAATATTCCTTTAGAAGATCA
  • refseq_EFEMP1.F1 (forward primer)
  • refseq_EFEMP1.R1 (reverse primer)
  • Single exon skipping

Frame 0

GLRQIRPTGLPSPAHSPRCPGPERSAAAQIHNV
ESPFPNYADSGAGQVTGHRRNHHVHAMH*RI*VG
SCETAMQRY**M*HCPRRL*RWNEVCQPLWRIP
LPSENSPDYCQ**TASAGNTTSRRNLRGNHRGC
SCQQHGNQWSVARGWFCGQCCCSRRP*NADWPK*
LCHPAEPS*PSAHSLQPFPPYPVCSRLRAK*TQ
RVPRHRRVHCRDAQL*SRPSVHQFTGILCMSVP
SWISEARGAVRRHR*MYHPSILPPKMREYTRLIL
LPVQSWVSIGSKQLYLRRYK*M*CQQSMCSAVL
QHSWFIHLSVQSRI*AKQ*QAQL*RH**MQNLK
LPVSISMCQ*TWEILMYVPPGIPSGEK*NMSRYK
*V*DHK*MPGG*NVLELSWRLPLLSTKSLSRSL
HSNTREPMCLPSLKCHVPRTAPVNSLQIHEHPI
**VCAIRHLPDTGHNYLCQHHQYFSD*IWK*KWR
VLPTTNKSCKCNACAREVIIRTKRTYRGPGDAD
SQQYRDLPHKLCVKIDNNSGAIFILVFSKSQPQ
AFKSAKEYCYLKALFYL*IYLVHLHLYTVHSPII
QTITPWYKVGI*YVKIQSLSLLLYVN*TLIH*T
GLLQES*VYTIW*NLDSFL*KWDQAMMIFCGA*
GNLLELH*QSHKEAAIITIE*HARVRMSF*LLCK
KMEKVNKDIFL*KMGICHICVGFYFHIQPKGGC
LLYSNKSLLYNMLVSVGYF*FCQKF*IVNIL*K
TVSKIFQNSQNEPDIP*KIILLRNLWGGYEKINS
F*TTLELT*RSKLGKYNNIPEFRTSTRCRTKWI
KGISLEKF*FLSKI*ILTLH*FITKISHLRT*C
SQRKKMMMVFIPGIQSDSELKQITLLPNSMEYFI
RLLV*NVTALL*CIIFLNKNKYSFRRS

Frame 1

DFARSDPRGCPPLRTPLAARARSAARPHRFTML
KALFLTMLTLALVKSQDTEETITYTQCTDGYEW
DPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYL
CLPKTAQIIVNNEQPQQETQPAEGTSGATTGVV
AASSMATSGVLPGGGFVASAAAVAGPEMQTGRN
NFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHN
VCQDIDECTAGTHNCRADQVCINLRGSFACQCP
PGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSF
YCQCSPGFQLAANNYTCVDINECDASNQCAQQCY
NILGSFICQCNQGYELSSDRLNCEDIDECRTSS
YLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDI
NECETTNECREDEMCWNYHGGFRCYPRNPCQDPY
ILTPENRCVCPVSNAMCRELPQSIVYKYMSIRS
DRSVPSDIFQIQATTIYANTINTFRIKSGNENG
EFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLT
VSSIGTFRTSSVLRLTIIVGPFSF*SFLRVNHR
HLSQPKNIVTLKHYFIYRYI*CIYISILYTHP*
FKQLHHGIKWAFNM*RFKVCLYYYM*IRH*STKL
VFFKRAKYTLSGETWILSYKSGTKQ**SSVVLK
ETY*SSTNSLIRRQPS*PLNSMQG*E*VFNCFV
RKWKRSIKIYFFRKWGSAIFVLVFIFISSLKVVV
YYIVINHCCTICWFL*GIFNFVRNFRL*IFCKK
Q*AKFSRIPKMNQISPRKLYY*EIYGEDMRK*I
PSKPHWN*PEEANSENIITSLNSGLPQDAEQNG*
KVFHWRSFNF*VKFKS*HFTNL*LKFLIFVLDA
HRGRK**WFLFLASRVTVNLSKLPSYPILWNIL
YVSLFKMSLLYFDVSYF*IKINIPLED

Frame 2

TSPDQTHGAALPCALPSLPGPGAQRGRTDSQC*
KPFS*LC*LWRWSSHRTPKKPSRTRNALTDMSG
IL*DSNAKILMNVTLSQTLVKVE*SVSTTMEDT
SAFRKQPRLLSIMNSLSRKHNQQKEPQGQPPGL*
LPAAWQPVECCPGVVLWPVLLQSQALKCRLAEI
TLSSGGTQLTLSAFPPTLPTVSSVQQATSKVNT
TCAKT*TSALQGRTTVEQTKCASIYGDPLHVSAL
LDIRSEGSSA*T*MNVPSLHIATKDA*IHQAHF
IASAVLGFNWQQTTIPA*I*MNVMPAINVLSSA
TTFLVHSSVSAIKDMS*AVTGSTVKTLMNAEPQA
TCVNINVSMNLGNSHVCAPRDTKW*EVEHVKI*
MSVRPQMNAGRMKCVGIIMAASVVIHEILVKIP
TF*HQRTDVFAQSQMPCAENCPSQ*STNT*ASDL
IGLCHQTSSRYRPQLFMPTPSILFGLNLEMKME
SSTYDKQVL*VQCLCS*SHYQDQENISWTWRC*
QSAV*GPSAQALC*D*Q**WGHFHFSLF*ESTTG
I*VSQRILLP*STILFIDISSASTSLYCTLTHN
SNNYTMV*SGHLICKDSKFVFITICKLDINPLN
WSSSRELSIHYLVKLGFFPIKVGPSNDDLLWCLR
KLTRAPLTVS*GGSHHNH*IACKGKNEFLTAL*
ENGKGQ*RYISLENGDLPYLCWFLFSYPA*RWL
FII***IIAVQYAGFCRVFLILSEILDCEYFVKN
SKQNFPEFPK*TRYPLENYTIEKSMGRI*ENKF
LLNHIGTDLKKQTRKI**HP*IQDFHKMQNKMD
KRYFTGEVLISK*NLNPNTSLIYN*NFSSSYLML
TEEENDDGFYSWHPE*Q*T*ANYPPTQFYGIFY
TSPCLKCHCFTLMYHIFK*K*IFL*KI

Sequence NM_001039348

GGACTTCGCCAGATCAGACCCACGGGGCTGCCCTCCCCTGCGCACTCCCCTCGCTGCCCGGGCCCGGAGCGCAGCGCGGCCGCACAGGTATTTTTGCTGT
GCTGTGCAAGGAACTCTGCTAGCTCAAG
ATTCACAATGTTGAAAGCCCTTTTCCTAACTATGCTGACTCTGGCGCTGGTCAAGTCACAGGACACCGAAGA
AACCATCA
CGTACACGCAATGCACTGACGGATATGAGTGGGATCCTGTGAGACAGCAATGCAAAGATATTGATGAATGTGACATTGTCCCAGACGCTTGT
AAAGGTGGAATGAAGTGTGTCAACCACTATGGAGGATACCTCTGCCTTCCGAAAACAGCCCAGATTATTGTCAATAATGAACAGCCTCAGCAGGAAACAC
AACCAGCAGAAGGAACCTCAGGGGCAACCACCGGGGTTGTAGCTGCCAGCAGCATGGCAACCAGTGGAGTGTTGCCCGGGGGTGGTTTTGTGGCCAGTGC
TGCTGCAGTCGCAGGCCCTGAAATGCAGACTGGCCGAAATAACTTTGTCATCCGGCGGAACCCAGCTGACCCTCAGCGCATTCCCTCCAACCCTTCCCAC
CGTATCCAGTGTGCAGCAGGCTACGAGCAAAGTGAACACAACGTGTGCCAAGACATAGACGAGTGCACTGCAGGGACGCACAACTGTAGAGCAGACCAAG
TGTGCATCAATTTACGGGGATCCTTTGCATGTCAGTGCCCTCCTGGATATCAGAAGCGAGGGGAGCAGTGCGTAGACATAGATGAATGTACCATCCCTCC
ATATTGCCACCAAAGATGCGTGAATACACCAGGCTCATTTTATTGCCAGTGCAGTCCTGGGTTTCAATTGGCAGCAAACAACTATACCTGCGTAGATATA
AATGAATGTGATGCCAGCAATCAATGTGCTCAGCAGTGCTACAACATTCTTGGTTCATTCATCTGTCAGTGCAATCAAGGATATGAGCTAAGCAGTGACA
GGCTCAACTGTGAAGACATTGATGAATGCAGAACCTCAAGCTACCTGTGTCAATATCAATGTGTCAATGAACCTGGGAAATTCTCATGTATGTGCCCCCA
GGGATACCAAGTGGTGAGAAGTAGAACATGTCAAGATATAAATGAGTGTGAGACCACAAATGAATGCCGGGAGGATGAAATGTGTTGGAATTATCATGGC
GGCTTCCGTTGTTATCCACGAAATCCTTGTCAAGATCCCTACATTCTAACACCAGAGAACCGATGTGTTTGCCCAGTCTCAAATGCCATGTGCCGAGAAC
TGCCCCAGTCAATAGTCTACAAATACATGAGCATCCGATCTGATAGGTCTGTGCCATCAGACATCTTCCAGATACAGGCCACAACTATTTATGCCAACAC
CATCAATACTTTTCGGATTAAATCTGGAAATGAAAATGGAGAGTTCTACCTACGACAAACAAGTCCTGTAAGTGCAATGCTTGTGCTCGTGAAGTCATTA
TCAGGACCAAGAGAACATATCGTGGACCTGGAGATGCTGACAGTCAGCAGTATAGGGACCTTCCGCACAAGCTCTGTGTTAAGATTGACAATAATAGTGG
GGCCATTTTCATTTTAGTCTTTTCTAAGAGTCAACCACAGGCATTTAAGTCAGCCAAAGAATATTGTTACCTTAAAGCACTATTTTATTTATAGATATAT
CTAGTGCATCTACATCTCTATACTGTACACTCACCCATAATTCAAACAATTACACCATGGTATAAAGTGGGCATTTAATATGTAAAGATTCAAAGTTTGT
CTTTATTACTATATGTAAATTAGACATTAATCCACTAAACTGGTCTTCTTCAAGAGAGCTAAGTATACACTATCTGGTGAAACTTGGATTCTTTCCTATA
AAAGTGGGACCAAGCAATGATGATCTTCTGTGGTGCTTAAGGAAACTTACTAGAGCTCCACTAACAGTCTCATAAGGAGGCAGCCATCATAACCATTGAA
TAGCATGCAAGGGTAAGAATGAGTTTTTAACTGCTTTGTAAGAAAATGGAAAAGGTCAATAAAGATATATTTCTTTAGAAAATGGGGATCTGCCATATTT
GTGTTGGTTTTTATTTTCATATCCAGCCTAAAGGTGGTTGTTTATTATATAGTAATAAATCATTGCTGTACAATATGCTGGTTTCTGTAGGGTATTTTTA
ATTTTGTCAGAAATTTTAGATTGTGAATATTTTGTAAAAAACAGTAAGCAAAATTTTCCAGAATTCCCAAAATGAACCAGATATCCCCTAGAAAATTATA
CTATTGAGAAATCTATGGGGAGGATATGAGAAAATAAATTCCTTCTAAACCACATTGGAACTGACCTGAAGAAGCAAACTCGGAAAATATAATAACATCC
CTGAATTCAGGACTTCCACAAGATGCAGAACAAAATGGATAAAAGGTATTTCACTGGAGAAGTTTTAATTTCTAAGTAAAATTTAAATCCTAACACTTCA
CTAATTTATAACTAAAATTTCTCATCTTCGTACTTGATGCTCACAGAGGAAGAAAATGATGATGGTTTTTATTCCTGGCATCCAGAGTGACAGTGAACTT
AAGCAAATTACCCTCCTACCCAATTCTATGGAATATTTTATACGTCTCCTTGTTTAAAATGTCACTGCTTTACTTTGATGTATCATATTTTTAAATAAAA
ATAAATATTCCTTTAGAAGATCA
  • refseq_EFEMP1.F1 (forward primer)
  • refseq_EFEMP1.R1 (reverse primer)
  • Single exon skipping

Frame 0

GLRQIRPTGLPSPAHSPRCPGPERSAAAQVFLL
CCARNSASSR
FTMLKALFLTMLTLALVKSQDTEE
TI
TYTQCTDGYEWDPVRQQCKDIDECDIVPDAC
KGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQET
QPAEGTSGATTGVVAASSMATSGVLPGGGFVASA
AAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSH
RIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQ
VCINLRGSFACQCPPGYQKRGEQCVDIDECTIPP
YCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDI
NECDASNQCAQQCYNILGSFICQCNQGYELSSD
RLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQ
GYQVVRSRTCQDINECETTNECREDEMCWNYHG
GFRCYPRNPCQDPYILTPENRCVCPVSNAMCRE
LPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANT
INTFRIKSGNENGEFYLRQTSPVSAMLVLVKSL
SGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIV
GPFSF*SFLRVNHRHLSQPKNIVTLKHYFIYRYI
*CIYISILYTHP*FKQLHHGIKWAFNM*RFKVC
LYYYM*IRH*STKLVFFKRAKYTLSGETWILSY
KSGTKQ**SSVVLKETY*SSTNSLIRRQPS*PLN
SMQG*E*VFNCFVRKWKRSIKIYFFRKWGSAIF
VLVFIFISSLKVVVYYIVINHCCTICWFL*GIF
NFVRNFRL*IFCKKQ*AKFSRIPKMNQISPRKLY
Y*EIYGEDMRK*IPSKPHWN*PEEANSENIITS
LNSGLPQDAEQNG*KVFHWRSFNF*VKFKS*HF
TNL*LKFLIFVLDAHRGRK**WFLFLASRVTVNL
SKLPSYPILWNILYVSLFKMSLLYFDVSYF*IK
INIPLED

Frame 1

DFARSDPRGCPPLRTPLAARARSAARPHRYFCC
AVQGTLLAQ
DSQC*KPFS*LC*LWRWSSHRTPK
KPS
RTRNALTDMSGIL*DSNAKILMNVTLSQTLV
KVE*SVSTTMEDTSAFRKQPRLLSIMNSLSRKH
NQQKEPQGQPPGL*LPAAWQPVECCPGVVLWPV
LLQSQALKCRLAEITLSSGGTQLTLSAFPPTLPT
VSSVQQATSKVNTTCAKT*TSALQGRTTVEQTK
CASIYGDPLHVSALLDIRSEGSSA*T*MNVPSL
HIATKDA*IHQAHFIASAVLGFNWQQTTIPA*I*
MNVMPAINVLSSATTFLVHSSVSAIKDMS*AVT
GSTVKTLMNAEPQATCVNINVSMNLGNSHVCAP
RDTKW*EVEHVKI*MSVRPQMNAGRMKCVGIIMA
ASVVIHEILVKIPTF*HQRTDVFAQSQMPCAEN
CPSQ*STNT*ASDLIGLCHQTSSRYRPQLFMPT
PSILFGLNLEMKMESSTYDKQVL*VQCLCS*SHY
QDQENISWTWRC*QSAV*GPSAQALC*D*Q**W
GHFHFSLF*ESTTGI*VSQRILLP*STILFIDI
SSASTSLYCTLTHNSNNYTMV*SGHLICKDSKFV
FITICKLDINPLNWSSSRELSIHYLVKLGFFPI
KVGPSNDDLLWCLRKLTRAPLTVS*GGSHHNH*
IACKGKNEFLTAL*ENGKGQ*RYISLENGDLPYL
CWFLFSYPA*RWLFII***IIAVQYAGFCRVFL
ILSEILDCEYFVKNSKQNFPEFPK*TRYPLENY
TIEKSMGRI*ENKFLLNHIGTDLKKQTRKI**HP
*IQDFHKMQNKMDKRYFTGEVLISK*NLNPNTS
LIYN*NFSSSYLMLTEEENDDGFYSWHPE*Q*T
*ANYPPTQFYGIFYTSPCLKCHCFTLMYHIFK*K
*IFL*KI

Frame 2

TSPDQTHGAALPCALPSLPGPGAQRGRTGIFAV
LCKELC*LK
IHNVESPFPNYADSGAGQVTGHRR
NHH
VHAMH*RI*VGSCETAMQRY**M*HCPRRL
*RWNEVCQPLWRIPLPSENSPDYCQ**TASAGNT
TSRRNLRGNHRGCSCQQHGNQWSVARGWFCGQC
CCSRRP*NADWPK*LCHPAEPS*PSAHSLQPFP
PYPVCSRLRAK*TQRVPRHRRVHCRDAQL*SRPS
VHQFTGILCMSVPSWISEARGAVRRHR*MYHPS
ILPPKMREYTRLILLPVQSWVSIGSKQLYLRRY
K*M*CQQSMCSAVLQHSWFIHLSVQSRI*AKQ*Q
AQL*RH**MQNLKLPVSISMCQ*TWEILMYVPP
GIPSGEK*NMSRYK*V*DHK*MPGG*NVLELSW
RLPLLSTKSLSRSLHSNTREPMCLPSLKCHVPRT
APVNSLQIHEHPI**VCAIRHLPDTGHNYLCQH
HQYFSD*IWK*KWRVLPTTNKSCKCNACAREVI
IRTKRTYRGPGDADSQQYRDLPHKLCVKIDNNSG
AIFILVFSKSQPQAFKSAKEYCYLKALFYL*IY
LVHLHLYTVHSPIIQTITPWYKVGI*YVKIQSL
SLLLYVN*TLIH*TGLLQES*VYTIW*NLDSFL*
KWDQAMMIFCGA*GNLLELH*QSHKEAAIITIE
*HARVRMSF*LLCKKMEKVNKDIFL*KMGICHI
CVGFYFHIQPKGGCLLYSNKSLLYNMLVSVGYF*
FCQKF*IVNIL*KTVSKIFQNSQNEPDIP*KII
LLRNLWGGYEKINSF*TTLELT*RSKLGKYNNI
PEFRTSTRCRTKWIKGISLEKF*FLSKI*ILTLH
*FITKISHLRT*CSQRKKMMMVFIPGIQSDSEL
KQITLLPNSMEYFIRLLV*NVTALL*CIIFLNK
NKYSFRRS

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