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Sequences

Sequence NM_002149

CGGCGGCGGCGGGCAGCGGACGGGCGGACTGACGGGCGCCTCCACCTTGCTCCCTCCCTGGCTGCCGGCTTCCTTTTGTCTTTCTGGGCGGCGATGAGCG CAGGGCCGGCGCAGCAGCTGCGGGCGCACGGAGGCCCGCGCTGCTAGTCACTCCTCCCGGCCTCGGCGCGCTTGTCCCGGGCAGCGGCCCGGGCCCGCTG CAGCCGCCGCCGGCGCCGAACTTGGGCTCGGGAAGCCGGCGGACCGCGTCCTGCGCCGGAGCAGGGGCATGGTCTAGTGGCCCAGTCAGGACGCGGAAAC ACTCCCTGGAGGTTCTGACCCACTCCCTCTCAGCCTCCGCCTGGTCTCTGGTGTAGTCGCCGCCGCCAGCCGCCATGGGCAAACAGAACAGCAAGCTGCG GCCCGAGGTGCTGCAGGACCTGCGGGAGAACACGGAGTTCACCGACCACGAGCTGCAGGAGTGGTACAAGGGCTTCCTCAAGGACTGCCCCACCGGCCAC CTGACCGTGGACGAGTTCAAGAAGATCTACGCCAACTTCTTCCCCTACGGCGACGCTTCCAAGTTCGCCGAGCACGTCTTCCGCACCTTCGACACCAACG GCGACGGCACCATCGACTTCCGGGAGTTCATCATTGCGCTGAGCGTGACCTCGCGGGGCAAGCTGGAGCAGAAGCTCAAGTGGGCCTTCAGCATGTACGA CCTGGACGGCAACGGCTACATCAGCCGCAGCGAGATGCTGGAGATCGTGCAGGCCATCTACAAGATGGTGTCGTCTGTGATGAAGATGCCGGAGGATGAG TCCACCCCGGAGAAGCGCACAGACAAGATCTTCAGGCAGATGGACACCAACAATGACGGCAAACTGTCCTTGGAAGAATTCATCAGAGGTGCCAAGAGCG ACCCCTCCATCGTCCGCCTGCTGCAGTGCGACCCCAGCAGTGCCAGTCAGTTCTGAGCGAGCGGCCCCTGGACAGTTGCAGAGAAACACAGGCTTGTCGT GCCGTTTAAGCTTTGCTTGCAAGAGTGGATGCCCCGCAATCGTTCCTGCTCTCCCGGGCCCCGGGCCTGGGGCATGCGTTGCACCTGCCCAGCCCGGTGG CTGCGCCTCCCTCCTCCACCTGACCAACGCGACATTCCTCCCCTCACGCCTGGCCCGGTCCCTTCCAGGGCAACTCCCAGGGATGTGGTGACATGCAGGG TTCAAGTGTTCTTGGTTCCAGGCACCTCCCGGCTCACGGGGAGCTCAGAGGTCCATGCCGAGGAGACCAGGCAGGACCTCCCGAGGCTGCGCCCCGGCCG GCCCATGCGTTTTGTGATCCCAAGTGACTCTGTGGGAAGGGTGGGGACGAGGCGTCGGGAGGGTATACAGGGAGCCCCTCCCGTGCATGGCTGCCCCCCC GTTCATTTTCTCCACCACAGCCGCTTGCACGTATAGATACTGTGGTCCCCTTTCTTTTAATATATAAATTATGTATGGTGAAGTGGAGTGTATTGTGTAG GTCCCGTATTTAATGCCTCTGACTGCCTTTGAAGCGCAGCCCTCTGTGGCCCGCAGCCCCCTGAGCCTGGCTGTTGTGTGGTATTTATGCTCTCTTTGTC TGCCTGTTTCTAAGGAAATGCATGTGTGCCCTGAGCCGTGATGATCCTCCCATCCGTGTTGTGAGCACAGGCATTTGTGTCTGGTCTGTCCTCCCTGTTG ATTGGTCTGGCATTTCCGGTATTAAAATGATAAAATAAATGGCATTTTCTGA

refseq_HPCAL1.F1 (forward primer)
refseq_HPCAL1.R1 (reverse primer)
Single exon skipping

Frame 0

RRRRAADGRTDGRLHLAPSLAAGFLLSFWAAMS AGPAQQLRAHGGPRC*SLLPASARLSRAAARARC SRRRRRTWAREAGGPRPAPEQGHGLVAQSGRGN TPWRF*PTPSQPPPGLWCSRRRQPPWANRTASC GPRCCRTCGRTRSSPTTSCRSGTRASSRTAPPAT *PWTSSRRSTPTSSPTATLPSSPSTSSAPSTPT ATAPSTSGSSSLR*A*PRGASWSRSSSGPSACT TWTATATSAAARCWRSCRPSTRWCRL**RCRRMS PPRRSAQTRSSGRWTPTMTANCPWKNSSEVPRA TPPSSACCSATPAVPVSSERAAPGQLQRNTGLS CRLSFACKSGCPAIVPALPGPGPGACVAPAQPGG CASLLHLTNATFLPSRLARSLPGQLPGMW*HAG FKCSWFQAPPGSRGAQRSMPRRPGRTSRGCAPA GPCVL*SQVTLWEGWGRGVGRVYREPLPCMAAPP FIFSTTAACTYRYCGPLSFNI*IMYGEVECIV* VPYLMPLTAFEAQPSVARSPLSLAVVWYLCSLC LPVSKEMHVCPEP**SSHPCCEHRHLCLVCPPC* LVWHFRY*NDKINGIF*

Frame 1

GGGGQRTGGLTGASTLLPPWLPASFCLSGRR*A QGRRSSCGRTEARAASHSSRPRRACPGQRPGPA AAAAGAELGLGKPADRVLRRSRGMV*WPSQDAET LPGGSDPLPLSLRLVSGVVAAASRHGQTEQQAA ARGAAGPAGEHGVHRPRAAGVVQGLPQGLPHRP PDRGRVQEDLRQLLPLRRRFQVRRARLPHLRHQR RRHHRLPGVHHCAERDLAGQAGAEAQVGLQHVR PGRQRLHQPQRDAGDRAGHLQDGVVCDEDAGG* VHPGEAHRQDLQADGHQQ*RQTVLGRIHQRCQER PLHRPPAAVRPQQCQSVLSERPLDSCRETQACR AV*ALLARVDAPQSFLLSRAPGLGHALHLPSPV AAPPSST*PTRHSSPHAWPGPFQGNSQGCGDMQG SSVLGSRHLPAHGELRGPCRGDQAGPPEAAPRP AHAFCDPK*LCGKGGDEASGGYTGSPSRAWLPP RSFSPPQPLARIDTVVPFLLIYKLCMVKWSVLCR SRI*CL*LPLKRSPLWPAAP*AWLLCGIYALFV CLFLRKCMCALSRDDPPIRVVSTGICVWSVLPV DWSGISGIKMIK*MAFS

Frame 2

AAAGSGRAD*RAPPPCSLPGCRLPFVFLGGDER RAGAAAAGARRPALLVTPPGLGALVPGSGPGPL QPPPAPNLGSGSRRTASCAGAGAWSSGPVRTRK HSLEVLTHSLSASAWSLV*SPPPAAMGKQNSKLR PEVLQDLRENTEFTDHELQEWYKGFLKDCPTGH LTVDEFKKIYANFFPYGDASKFAEHVFRTFDTN GDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYD LDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDE STPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKS DPSIVRLLQCDPSSASQF*ASGPWTVAEKHRLVV PFKLCLQEWMPRNRSCSPGPRAWGMRCTCPARW LRLPPPPDQRDIPPLTPGPVPSRATPRDVVTCR VQVFLVPGTSRLTGSSEVHAEETRQDLPRLRPGR PMRFVIPSDSVGRVGTRRREGIQGAPPVHGCPP VHFLHHSRLHV*ILWSPFF*YINYVW*SGVYCV GPVFNASDCL*SAALCGPQPPEPGCCVVFMLSLS ACF*GNACVP*AVMILPSVL*AQAFVSGLSSLL IGLAFPVLK**NKWHFL

Sequence NM_134421

AGCTTCTGCCAAGGGTGGGGGCCCACGCGGAGGCGATCCGCTCGTTCCTCCCAGGGCCATGGGGCGACGAGGAGAGCCCTGGCCTCCCCGCGACCCGCAC TGCGACCTGGGCCAGACGCGCCACCTTCCCCGGTCGCGGTTTGCTTCTCTTTAAAATGAGGACAGCTCCTCCCTTGGGGGCTGTGGTGACAGGTGAAATG AGAACGCACTGAAGACAGCTCTTGGTCCAAAGCCCCGCACACAGGGCATGGTCTAGTGGCCCAGTCAGGACGCGGAAACACTCCCTGGAGGTTCTGACCC ACTCCCTCTCAGCCTCCGCCTGGTCTCTGGGTTGGCTGTTCCAGCTCCAAAGAGAAGGAGGAACCTTTTCCTTCTGCAGCCCCTCCCCACCAGCCTCATT CCTTAGCTGGGGTCAGACCTGGGGTCCTCACTGCAGCTGGCCTCTGGCAGCGTTCTCAGGCTAGCCCTCCCTGCTGAAAAGAGAACCGTGTGGGACTCAC AGGTGTAGTCGCCGCCGCCAGCCGCCATGGGCAAACAGAACAGCAAGCTGCGGCCCGAGGTGCTGCAGGACCTGCGGGAGAACACGGAGTTCACCGACCA CGAGCTGCAGGAGTGGTACAAGGGCTTCCTCAAGGACTGCCCCACCGGCCACCTGACCGTGGACGAGTTCAAGAAGATCTACGCCAACTTCTTCCCCTAC GGCGACGCTTCCAAGTTCGCCGAGCACGTCTTCCGCACCTTCGACACCAACGGCGACGGCACCATCGACTTCCGGGAGTTCATCATTGCGCTGAGCGTGA CCTCGCGGGGCAAGCTGGAGCAGAAGCTCAAGTGGGCCTTCAGCATGTACGACCTGGACGGCAACGGCTACATCAGCCGCAGCGAGATGCTGGAGATCGT GCAGGCCATCTACAAGATGGTGTCGTCTGTGATGAAGATGCCGGAGGATGAGTCCACCCCGGAGAAGCGCACAGACAAGATCTTCAGGCAGATGGACACC AACAATGACGGCAAACTGTCCTTGGAAGAATTCATCAGAGGTGCCAAGAGCGACCCCTCCATCGTCCGCCTGCTGCAGTGCGACCCCAGCAGTGCCAGTC AGTTCTGAGCGAGCGGCCCCTGGACAGTTGCAGAGAAACACAGGCTTGTCGTGCCGTTTAAGCTTTGCTTGCAAGAGTGGATGCCCCGCAATCGTTCCTG CTCTCCCGGGCCCCGGGCCTGGGGCATGCGTTGCACCTGCCCAGCCCGGTGGCTGCGCCTCCCTCCTCCACCTGACCAACGCGACATTCCTCCCCTCACG CCTGGCCCGGTCCCTTCCAGGGCAACTCCCAGGGATGTGGTGACATGCAGGGTTCAAGTGTTCTTGGTTCCAGGCACCTCCCGGCTCACGGGGAGCTCAG AGGTCCATGCCGAGGAGACCAGGCAGGACCTCCCGAGGCTGCGCCCCGGCCGGCCCATGCGTTTTGTGATCCCAAGTGACTCTGTGGGAAGGGTGGGGAC GAGGCGTCGGGAGGGTATACAGGGAGCCCCTCCCGTGCATGGCTGCCCCCCCGTTCATTTTCTCCACCACAGCCGCTTGCACGTATAGATACTGTGGTCC CCTTTCTTTTAATATATAAATTATGTATGGTGAAGTGGAGTGTATTGTGTAGGTCCCGTATTTAATGCCTCTGACTGCCTTTGAAGCGCAGCCCTCTGTG GCCCGCAGCCCCCTGAGCCTGGCTGTTGTGTGGTATTTATGCTCTCTTTGTCTGCCTGTTTCTAAGGAAATGCATGTGTGCCCTGAGCCGTGATGATCCT CCCATCCGTGTTGTGAGCACAGGCATTTGTGTCTGGTCTGTCCTCCCTGTTGATTGGTCTGGCATTTCCGGTATTAAAATGATAAAATAAATGGCATTTT CTGA

refseq_HPCAL1.F1 (forward primer)
refseq_HPCAL1.R1 (reverse primer)
Single exon skipping

Frame 0

SFCQGWGPTRRRSARSSQGHGATRRALASPRPA LRPGPDAPPSPVAVCFSLK*GQLLPWGLW*QVK* ERTEDSSWSKAPHTGHGLVAQSGRGNTPWRF*P TPSQPPPGLWVGCSSSKEKEEPFPSAAPPHQPH SLAGVRPGVLTAAGLWQRSQASPPC*KENRVGLT GVVAAASRHGQTEQQAAARGAAGPAGEHGVHRP RAAGVVQGLPQGLPHRPPDRGRVQEDLRQLLPL RRRFQVRRARLPHLRHQRRRHHRLPGVHHCAERD LAGQAGAEAQVGLQHVRPGRQRLHQPQRDAGDR AGHLQDGVVCDEDAGG*VHPGEAHRQDLQADGH QQ*RQTVLGRIHQRCQERPLHRPPAAVRPQQCQS VLSERPLDSCRETQACRAV*ALLARVDAPQSFL LSRAPGLGHALHLPSPVAAPPSST*PTRHSSPH AWPGPFQGNSQGCGDMQGSSVLGSRHLPAHGELR GPCRGDQAGPPEAAPRPAHAFCDPK*LCGKGGD EASGGYTGSPSRAWLPPRSFSPPQPLARIDTVV PFLLIYKLCMVKWSVLCRSRI*CL*LPLKRSPLW PAAP*AWLLCGIYALFVCLFLRKCMCALSRDDP PIRVVSTGICVWSVLPVDWSGISGIKMIK*MAF S

Frame 1

ASAKGGGPRGGDPLVPPRAMGRRGEPWPPRDPH CDLGQTRHLPRSRFASL*NEDSSSLGGCGDR*N ENALKTALGPKPRTQGMV*WPSQDAETLPGGSDP LPLSLRLVSGLAVPAPKRRRNLFLLQPLPTSLI P*LGSDLGSSLQLASGSVLRLALPAEKRTVWDS QV*SPPPAAMGKQNSKLRPEVLQDLRENTEFTDH ELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPY GDASKFAEHVFRTFDTNGDGTIDFREFIIALSV TSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIV QAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDT NNDGKLSLEEFIRGAKSDPSIVRLLQCDPSSAS QF*ASGPWTVAEKHRLVVPFKLCLQEWMPRNRSC SPGPRAWGMRCTCPARWLRLPPPPDQRDIPPLT PGPVPSRATPRDVVTCRVQVFLVPGTSRLTGSS EVHAEETRQDLPRLRPGRPMRFVIPSDSVGRVGT RRREGIQGAPPVHGCPPVHFLHHSRLHV*ILWS PFF*YINYVW*SGVYCVGPVFNASDCL*SAALC GPQPPEPGCCVVFMLSLSACF*GNACVP*AVMIL PSVL*AQAFVSGLSSLLIGLAFPVLK**NKWHF L

Frame 2

LLPRVGAHAEAIRSFLPGPWGDEESPGLPATRT ATWARRATFPGRGLLLFKMRTAPPLGAVVTGEM RTH*RQLLVQSPAHRAWSSGPVRTRKHSLEVLT HSLSASAWSLGWLFQLQREGGTFSFCSPSPPASF LSWGQTWGPHCSWPLAAFSG*PSLLKREPCGTH RCSRRRQPPWANRTASCGPRCCRTCGRTRSSPT TSCRSGTRASSRTAPPAT*PWTSSRRSTPTSSPT ATLPSSPSTSSAPSTPTATAPSTSGSSSLR*A* PRGASWSRSSSGPSACTTWTATATSAAARCWRS CRPSTRWCRL**RCRRMSPPRRSAQTRSSGRWTP TMTANCPWKNSSEVPRATPPSSACCSATPAVPV SSERAAPGQLQRNTGLSCRLSFACKSGCPAIVP ALPGPGPGACVAPAQPGGCASLLHLTNATFLPSR LARSLPGQLPGMW*HAGFKCSWFQAPPGSRGAQ RSMPRRPGRTSRGCAPAGPCVL*SQVTLWEGWG RGVGRVYREPLPCMAAPPFIFSTTAACTYRYCGP LSFNI*IMYGEVECIV*VPYLMPLTAFEAQPSV ARSPLSLAVVWYLCSLCLPVSKEMHVCPEP**S SHPCCEHRHLCLVCPPC*LVWHFRY*NDKINGIF *