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Sequences

Sequence NM_001017408

GGGAGGTGGGACTGACTGAGTCTTCCGTGTGTCGCCGCCGTTGCCGCCTCAGCTTCAGCCTCGTTACTCCTGCGGTTCTGTGACTGTGCTGCTGGCGTTA ACGGCGCGAGGTGAAGGGAGGTGACGGAGTGTGCCCGCGCGCGCGGGGGTCCCCTCAGTCCCAGCAGTTCCCTTCGTGCGCGGGGGGCGGCGAGGGTCTT CAGCAGTCGGGAGAGGCCCTTGACGGCGCCATGTCGGCGGGCGGTCCATGCCCAGCAGCAGCCGGAGGGGGCCCAGGGGGCGCCTCCTGCTCCGTGGGGG CCCCTGGCGGGGTATCCATGTTCCGGTGGCTGGAGGTGCTGGAGAAGGAGTTCGACAAAGCTTTTGTGGATGTGGATCTGCTCCTGGGAGAGATCGATCC AGACCAAGCGGACATCACTTATGAGGGGCGACAGAAGATGACCAGCCTGAGCTCCTGCTTTGCACAGCTTTGCCACAAAGCCCAGTCTGTGTCTCAAATC AACCACAAGCTGGAGGCACAGTTGGTGGATCTGAAATCTGAACTGACAGAAACCCAAGCAGAGAAAGTTGTTTTGGAGAAAGAAGTACATGATCAGCTTT TACAGCTGCACTCTATTCAGCTGCAGCTTCATGCTAAAACTGGTCAAAGTGCTGACTCTGGTACCATTAAGGCAAAATTGGAAAGAGAGCTTGAGGCAAA CAAAAAAGAAAAAATGAAAGAAGCACAACTTGAAGCTGAAGTGAAATTGTTGAGAAAAGAGAATGAAGCCCTTCGTAGACATATAGCTGTTCTCCAGGCT GAAGTATATGGGGCGAGACTAGCTGCCAAGTACTTGGATAAGGAACTGGCAGGAAGGGTCCAACAGATACAATTGCTAGGACGAGATATGAAGGGACCTG CTCATGATAAGCTTTGGAACCAATTAGAAGCTGAAATACATTTGCATCGTCACAAAACTGTGATCCGAGCCTGCAGAGGACGTAATGACTTGAAACGACC AATGCAAGCACCACCAGGCCATGATCAAGATTCCCTAAAGAAAAGCCAAGGTGTTGGTCCAATTAGAAAAGTTCTCCTCCTTAAGGAAGATCATGAAGGC CTTGGCATTTCAATTACAGGTGGGAAAGAACATGGTGTTCCAATCCTCATCTCTGAGATCCATCCGGGGCAACCTGCTGATAGATGCGGAGGGCTGCACG TTGGGGATGCTATTTTGGCAGTCAACGGAGTTAACCTAAGGGACACAAAGCATAAAGAAGCTGTAACTATTCTTTCTCAGCAGAGAGGAGAGATTGAATT TGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGTTACCGTTTGTACCTTGATGAGTTA GAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGGATTTAATAAGAAGGCAGTAACTGACACACATGAAA ATGGAGACCTGGGCACTGCAAGTGAAACTCCGCTAGATGACGGTGCTTCAAAATTAGATGATCTGCACACTCTGTATCATAAAAAATCTTATTAAATTGA CCATATCTCCAGACAAGATTGTTAATCAGACTATTCTGAATTTGGGGCACTGGGGAAGATGGTGACAAAGACTACAAAATCAGGGGAGGCTGTTTGTTGC CTAAATGAAAGGCGGGTACCTCAGGGCTTCATGTGAACAATTCTCAATGCATAAAACACCCTGTTTTCTGTGGTAGACCATAATTAGCTATTGCATGTAA AGCAATTTTGATTTTCTTGAACTTGTAAGCACCAAAGCATGTGTTTCCCAAAGGGGTATTACTGGGCTCTTAAGTACCAAATGAAACCCTACTGTTTTAC TTGGTTCCTTTTCCCTTTAGTAGGAGGACAGTGCTAACTGGAATTTTATAAGGAGTACCCTTTAAAATACAGAGAGTAAGTGAATTCATATTTTATATTC TAGAATGTTAACTGTGGTATTTCAGAAGACAGAGCTTGACTCAATGAATTGTAGAAATATAGGCTTGACTTAATTTTTGTAACTGAAAGGCTTTAGACTT AAAAAAATTTATTGTGCATCCTAAAATCTAAACCAATTATTAATGATCATTTATTGTAATGAGTTTGCATTTCAGCTTTATTCAATGCAGTACAAAATAG TTTTCTTTAAGCAGTCTTTTATCAATCAATGCTGCACTAGAAATAGATTCTCAAAAGTTACTAAACATTTTACTTTTTTTGTTTTTTAAAAGAAATGCAG ATGAGTGTAAAACATCTGTTCTCAATTATGTTGATCTGTGTGCGCAGTACTGGAGCATTTACCCATTCATGTTGAGCCTCAAATGCTTGTTTTCTGGGGT CCACAAAAGACAGTTTTATACATTTTGAGTTGTTCATAAAGTTTGTCTTGTGATAGTCCTGGCACTTAAAGACAAATTTTTCTGGTAGTAAAAGTTCAGA TTTATTACTATGTCATGAAACACAGTACATTCAAATCAAACGGCAGTTTTCTTTCTAAGTAAATGATTTCCAGTCATCTAAAAGGTGGGCAAGATGAGAT AAAGACATTTTGATACAGTAATTGTTTTGGTTGGGTTTTCATGTCAGTTTATGTTTGACTAAAGCTCTCTTCATATGCAGGTTTATAAATTTGTTAGGTC TGTTGTCCCATGATTAAACATGGAGTGCCTCCTCTCTGATTTAATATTCTGCAGGTCATTGTAACCTGCTAGGCAAAGTCACAACATTGCATTAAAGAGG TGATAGCTTTGCTAATATCACTGTTTTAAAGGACGTACAGTTAAAGGAATATTAAGTGGGAGAAAGCCTACAAGGCTTTTAGAATATTATCAGTATCTTC ATTTCTGGTATTCAGATGTTATGTGATAAAACACATTTTTTTTGGCTTTCCCAGATACACTATATATTTGTTCAAGGGTAAATCTATAAAATGTATATAC TTTATTTTGTGGTTTTGCTATTTATAAATTTAATGTTTTAACTGTTGCTCATTTATGGTTTGTTTTGGGTGGTGGTGTTCATCTGTATATCACCATGTTA ATTTGTAATGGAAGTGCACTTCGTAGTGTATATTGTTACTGACATTAAAATACTTTATAGCATTGTCTCTGAGCAAAAGCTAGTATTTAATTGTACAAAT GAATAAGCAAGTTACATGTTATTGTTTGCTCTTGACAGGGTAGGCCTCTTAAAAGAAAAAAAACAACTTGTTTTTTCTTTATGAATCCCCTATGCCAAAC ACATACCTTCCATGCATGACATGAGATCTGCAAACTGGATTTTAGCCACCGTATTTATTTAGTCAAAAAAATTGTCCATTGTAGCAGACCCGAAAACCTT TTTGCTGTGACATGAAACCATGTTATTCTTATCTTCTTAAAACACAGCCTGGGATGGAATGGCCATGGCATTTTTTTCAGAGAACATCCTTTATCTGCTA TGACTGAATCCTTAGGAAATGTAAGCTATAACCCTTTGATTTTCAAGAACTACCGAATAAGTGTATGAAGAGGTGGTTTTTTAAAACTTCAAGTTGGAAT TTTTATGAGGTCACTGTGTAATTTGAAGAATTGTGTGAGATTGTCATGATATAAATTCCTTTTAAGGACTGATAAATAGAATGAAAAGTTTCCAGGTAGT TTAAAACTCCACAGGTCAGTTTCCTTTTCATTCCTGCTTCACTGTGGTTTATAAGCCTACGGGAGAGCACCGTTGCTCAGATGCTACTGTGAGCTTCCTG TCCGGTGTTAGAAAGTAACTAGTTAAAAGTTCATTTTAGAATGTATGGTTTTTGGGGATGAACTAAGAATTAGTTATTAGTTCCAAAGGACTGAGAACCA ATTTTAATATTTTCACATTTATAGGAAAGAAATTCATATGTCCCTGAAACTTCTAGGACAAAACCAAACAAGTAAGGAGGGAACTGTTGCAAAGCCATTT CATCGAGAAGGGGACAGAAGGAGAAATACACACATGTATACACAAACAGAATGGTTGAGAAAACGTTTTAATAAAATGTGAGGGTTGTATGTGTGCGTGT ATATATTTACACTTAACCTCTAAAATTCTCTTCTACAGTATCTCTGTTATGAATATGATGGAAAAGCAACATTTTGGTGGTGAGACTATTGTTAAAATAA ATTTGAGAAAGACGAAAATTTTGTGAGTCTTGATAATTACAAGTCAACAGCTATCGAAAGTTAGCACAGCTTGTCTGTGGTGCTGTTTTTTTCCCCACTG CAGTGGACTTATGCTGTTTTCATGTTTAGAAACAAAAAGGTTTCATGTGATTCATGTGTAAGATGCACAGTATTTGACATCCTGATTATGTAATCCCTAT TCCATCTATCCAGTCTTACACTTATGGTTGGCCTCAAATCTATTGCATTTATGATAATGTATTATATCTAGTTGAGTTTAATATTTTTTTATTAGCCTGT AAATAAAGATGGCATCTTCTACATTAAAATGATATTGATCTCATTTTTTTAAATAAACATTTTGTTTCCTTGACGTTAAA

refseq_GOPC.F1 (forward primer)
refseq_GOPC.R1 (reverse primer)
Single exon skipping

Frame 0

GRWD*LSLPCVAAVAASASASLLLRFCDCAAGV NGAR*REVTECARARGGPLSPSSSLRARGAARVF SSRERPLTAPCRRAVHAQQQPEGAQGAPPAPWG PLAGYPCSGGWRCWRRSSTKLLWMWICSWERSI QTKRTSLMRGDRR*PA*APALHSFATKPSLCLKS TTSWRHSWWI*NLN*QKPKQRKLFWRKKYMISF YSCTLFSCSFMLKLVKVLTLVPLRQNWKESLRQ TKKKK*KKHNLKLK*NC*EKRMKPFVDI*LFSRL KYMGRD*LPSTWIRNWQEGSNRYNC*DEI*RDL LMISFGTN*KLKYICIVTKL*SEPAEDVMT*ND QCKHHQAMIKIP*RKAKVLVQLEKFSSLRKIMKA LAFQLQVGKNMVFQSSSLRSIRGNLLIDAEGCT LGMLFWQSTELT*GTQSIKKL*LFFLSREERLN LK*FMWLLKWILMMKT*SMKMRVDIVTVCTLMS* KEVVTLVLVAKTQVGKSKYYKDLIRRQ*LTHMK METWALQVKLR*MTVLQN*MICTLCIIKNLIKL TISPDKIVNQTILNLGHWGRW*QRLQNQGRLFVA *MKGGYLRASCEQFSMHKTPCFLW*TIISYCM* SNFDFLELVSTKACVSQRGITGLLSTK*NPTVL LGSFSL**EDSANWNFIRSTL*NTESK*IHILYS RMLTVVFQKTELDSMNCRNIGLT*FL*LKGFRL KKIYCAS*NLNQLLMIIYCNEFAFQLYSMQYKI VFFKQSFINQCCTRNRFSKVTKHFTFFVF*KKCR *V*NICSQLC*SVCAVLEHLPIHVEPQMLVFWG PQKTVLYILSCS*SLSCDSPGT*RQIFLVVKVQ IYYYVMKHSTFKSNGSFLSK*MISSHLKGGQDEI KTF*YSNCFGWVFMSVYV*LKLSSYAGL*IC*V CCPMIKHGVPPL*FNILQVIVTC*AKSQHCIKE VIALLISLF*RTYS*RNIKWEKAYKAFRILSVSS FLVFRCYVIKHIFFGFPRYTIYLFKGKSIKCIY FILWFCYL*I*CFNCCSFMVCFGWWCSSVYHHV NL*WKCTS*CILLLTLKYFIALSLSKS*YLIVQM NKQVTCYCLLLTG*AS*KKKNNLFFLYESPMPN TYLPCMT*DLQTGF*PPYLFSQKNCPL*QTRKP FCCDMKPCYSYLLKTQPGMEWPWHFFQRTSFICY D*ILRKCKL*PFDFQELPNKCMKRWFFKTSSWN FYEVTV*FEELCEIVMI*IPFKD**IE*KVSR* FKTPQVSFLFIPASLWFISLRESTVAQMLL*ASC PVLESN*LKVHFRMYGFWG*TKN*LLVPKD*EP ILIFSHL*ERNSYVPETSRTKPNK*GGNCCKAI SSRRGQKEKYTHVYTNRMVEKTF**NVRVVCVRV YIYT*PLKFSSTVSLL*I*WKSNILVVRLLLK* I*ERRKFCES**LQVNSYRKLAQLVCGAVFFPT AVDLCCFHV*KQKGFM*FMCKMHSI*HPDYVIPI PSIQSYTYGWPQIYCIYDNVLYLVEFNIFLLAC K*RWHLLH*NDIDLIFLNKHFVSLTL

Frame 1

GGGTD*VFRVSPPLPPQLQPRYSCGSVTVLLAL TARGEGR*RSVPARAGVPSVPAVPFVRGGRRGS SAVGRGP*RRHVGGRSMPSSSRRGPRGRLLLRGG PWRGIHVPVAGGAGEGVRQSFCGCGSAPGRDRS RPSGHHL*GATEDDQPELLLCTALPQSPVCVSN QPQAGGTVGGSEI*TDRNPSRESCFGERST*SAF TAALYSAAASC*NWSKC*LWYH*GKIGKRA*GK QKRKNERSTT*S*SEIVEKRE*SPS*TYSCSPG *SIWGETSCQVLG*GTGRKGPTDTIARTRYEGTC S**ALEPIRS*NTFASSQNCDPSLQRT**LETT NASTTRP*SRFPKEKPRCWSN*KSSPP*GRS*R PWHFNYRWERTWCSNPHL*DPSGATC**MRRAAR WGCYFGSQRS*PKGHKA*RSCNYSFSAERRD*I *SSLCGS*SGF***KRRV*R*EWTSLPFVP**V RRRW*PWC*LQRHKWGNQSITRI**EGSN*HT*K WRPGHCK*NSAR*RCFKIR*SAHSVS*KILLN* PYLQTRLLIRLF*IWGTGEDGDKDYKIRGGCLL PK*KAGTSGLHVNNSQCIKHPVFCGRP*LAIACK AILIFLNL*APKHVFPKGVLLGS*VPNETLLFY LVPFPFSRRTVLTGIL*GVPFKIQRVSEFIFYI LEC*LWYFRRQSLTQ*IVEI*A*LNFCN*KALDL KKFIVHPKI*TNY**SFIVMSLHFSFIQCSTK* FSLSSLLSINAALEIDSQKLLNILLFLFFKRNA DECKTSVLNYVDLCAQYWSIYPFMLSLKCLFSGV HKRQFYTF*VVHKVCLVIVLALKDKFFW**KFR FITMS*NTVHSNQTAVFFLSK*FPVI*KVGKMR *RHFDTVIVLVGFSCQFMFD*SSLHMQVYKFVRS VVP*LNMECLLSDLIFCRSL*PARQSHNIALKR **LC*YHCFKGRTVKGILSGRKPTRLLEYYQYL HFWYSDVM**NTFFLAFPDTLYICSRVNL*NVYT LFCGFAIYKFNVLTVAHLWFVLGGGVHLYITML ICNGSALRSVYCY*H*NTL*HCL*AKASI*LYK *ISKLHVIVCS*QGRPLKRKKTTCFFFMNPLCQT HTFHA*HEICKLDFSHRIYLVKKIVHCSRPENL FAVT*NHVILIFLKHSLGWNGHGIFFREHPLSA MTESLGNVSYNPLIFKNYRISV*RGGFLKLQVGI FMRSLCNLKNCVRLS*YKFLLRTDK*NEKFPGS LKLHRSVSFSFLLHCGL*AYGRAPLLRCYCELP VRC*KVTS*KFILECMVFGDELRISY*FQRTENQ F*YFHIYRKEIHMSLKLLGQNQTSKEGTVAKPF HREGDRRRNTHMYTQTEWLRKRFNKM*GLYVCV YIFTLNL*NSLLQYLCYEYDGKATFWW*DYC*NK FEKDENFVSLDNYKSTAIES*HSLSVVLFFSPL QWTYAVFMFRNKKVSCDSCVRCTVFDILIM*SL FHLSSLTLMVGLKSIAFMIMYYI*LSLIFFY*PV NKDGIFYIKMILISFF*INILFP*R*

Frame 2

EVGLTESSVCRRRCRLSFSLVTPAVL*LCCWR* RREVKGGDGVCPRARGSPQSQQFPSCAGGGEGL QQSGEALDGAMSAGGPCPAAAGGGPGGASCSVG APGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDP DQADITYEGRQKMTSLSSCFAQLCHKAQSVSQI NHKLEAQLVDLKSELTETQAEKVVLEKEVHDQL LQLHSIQLQLHAKTGQSADSGTIKAKLERELEAN KKEKMKEAQLEAEVKLLRKENEALRRHIAVLQA EVYGARLAAKYLDKELAGRVQQIQLLGRDMKGP AHDKLWNQLEAEIHLHRHKTVIRACRGRNDLKRP MQAPPGHDQDSLKKSQGVGPIRKVLLLKEDHEG LGISITGGKEHGVPILISEIHPGQPADRCGGLH VGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEF EVVYVAPEVDSDDENVEYEDESGHRYRLYLDEL EGGGNPGASCKDTSGEIKVLQGFNKKAVTDTHE NGDLGTASETPLDDGASKLDDLHTLYHKKSY*ID HISRQDC*SDYSEFGALGKMVTKTTKSGEAVCC LNERRVPQGFM*TILNA*NTLFSVVDHN*LLHV KQF*FS*TCKHQSMCFPKGYYWALKYQMKPYCFT WFLFPLVGGQC*LEFYKEYPLKYRE*VNSYFIF *NVNCGISEDRA*LNEL*KYRLDLIFVTERL*T *KNLLCILKSKPIINDHLL**VCISALFNAVQNS FL*AVFYQSMLH*K*ILKSY*TFYFFCFLKEMQ MSVKHLFSIMLICVRSTGAFTHSC*ASNACFLG STKDSFIHFELFIKFVL**SWHLKTNFSGSKSSD LLLCHETQYIQIKRQFSF*VNDFQSSKRWAR*D KDILIQ*LFWLGFHVSLCLTKALFICRFINLLG LLSHD*TWSASSLI*YSAGHCNLLGKVTTLH*RG DSFANITVLKDVQLKEY*VGESLQGF*NIISIF ISGIQMLCDKTHFFWLSQIHYIFVQG*IYKMYI LYFVVLLFINLMF*LLLIYGLFWVVVFICISPC* FVMEVHFVVYIVTDIKILYSIVSEQKLVFNCTN E*ASYMLLFALDRVGLLKEKKQLVFSL*IPYAK HIPSMHDMRSANWILATVFI*SKKLSIVADPKTF LL*HETMLFLSS*NTAWDGMAMAFFSENILYLL *LNP*EM*AITL*FSRTTE*VYEEVVF*NFKLE FL*GHCVI*RIV*DCHDINSF*GLINRMKSFQVV *NSTGQFPFHSCFTVVYKPTGEHRCSDATVSFL SGVRK*LVKSSF*NVWFLGMN*ELVISSKGLRT NFNIFTFIGKKFICP*NF*DKTKQVRRELLQSHF IEKGTEGEIHTCIHKQNG*ENVLIKCEGCMCAC IYLHLTSKILFYSISVMNMMEKQHFGGETIVKI NLRKTKIL*VLIITSQQLSKVSTACLWCCFFPHC SGLMLFSCLETKRFHVIHV*DAQYLTS*LCNPY SIYPVLHLWLASNLLHL**CIISS*V*YFFISL *IKMASSTLK*Y*SHFFK*TFCFLDVK

Sequence NM_020399

GGGAGGTGGGACTGACTGAGTCTTCCGTGTGTCGCCGCCGTTGCCGCCTCAGCTTCAGCCTCGTTACTCCTGCGGTTCTGTGACTGTGCTGCTGGCGTTA ACGGCGCGAGGTGAAGGGAGGTGACGGAGTGTGCCCGCGCGCGCGGGGGTCCCCTCAGTCCCAGCAGTTCCCTTCGTGCGCGGGGGGCGGCGAGGGTCTT CAGCAGTCGGGAGAGGCCCTTGACGGCGCCATGTCGGCGGGCGGTCCATGCCCAGCAGCAGCCGGAGGGGGCCCAGGGGGCGCCTCCTGCTCCGTGGGGG CCCCTGGCGGGGTATCCATGTTCCGGTGGCTGGAGGTGCTGGAGAAGGAGTTCGACAAAGCTTTTGTGGATGTGGATCTGCTCCTGGGAGAGATCGATCC AGACCAAGCGGACATCACTTATGAGGGGCGACAGAAGATGACCAGCCTGAGCTCCTGCTTTGCACAGCTTTGCCACAAAGCCCAGTCTGTGTCTCAAATC AACCACAAGCTGGAGGCACAGTTGGTGGATCTGAAATCTGAACTGACAGAAACCCAAGCAGAGAAAGTTGTTTTGGAGAAAGAAGTACATGATCAGCTTT TACAGCTGCACTCTATTCAGCTGCAGCTTCATGCTAAAACTGGTCAAAGTGCTGACTCTGGTACCATTAAGGCAAAATTGTCTGGCCCCTCTGTGGAGGA GCTGGAAAGAGAGCTTGAGGCAAACAAAAAAGAAAAAATGAAAGAAGCACAACTTGAAGCTGAAGTGAAATTGTTGAGAAAAGAGAATGAAGCCCTTCGT AGACATATAGCTGTTCTCCAGGCTGAAGTATATGGGGCGAGACTAGCTGCCAAGTACTTGGATAAGGAACTGGCAGGAAGGGTCCAACAGATACAATTGC TAGGACGAGATATGAAGGGACCTGCTCATGATAAGCTTTGGAACCAATTAGAAGCTGAAATACATTTGCATCGTCACAAAACTGTGATCCGAGCCTGCAG AGGACGTAATGACTTGAAACGACCAATGCAAGCACCACCAGGCCATGATCAAGATTCCCTAAAGAAAAGCCAAGGTGTTGGTCCAATTAGAAAAGTTCTC CTCCTTAAGGAAGATCATGAAGGCCTTGGCATTTCAATTACAGGTGGGAAAGAACATGGTGTTCCAATCCTCATCTCTGAGATCCATCCGGGGCAACCTG CTGATAGATGCGGAGGGCTGCACGTTGGGGATGCTATTTTGGCAGTCAACGGAGTTAACCTAAGGGACACAAAGCATAAAGAAGCTGTAACTATTCTTTC TCAGCAGAGAGGAGAGATTGAATTTGAAGTAGTTTATGTGGCTCCTGAAGTGGATTCTGATGATGAAAACGTAGAGTATGAAGATGAGAGTGGACATCGT TACCGTTTGTACCTTGATGAGTTAGAAGGAGGTGGTAACCCTGGTGCTAGTTGCAAAGACACAAGTGGGGAAATCAAAGTATTACAAGGATTTAATAAGA AGGCAGTAACTGACACACATGAAAATGGAGACCTGGGCACTGCAAGTGAAACTCCGCTAGATGACGGTGCTTCAAAATTAGATGATCTGCACACTCTGTA TCATAAAAAATCTTATTAAATTGACCATATCTCCAGACAAGATTGTTAATCAGACTATTCTGAATTTGGGGCACTGGGGAAGATGGTGACAAAGACTACA AAATCAGGGGAGGCTGTTTGTTGCCTAAATGAAAGGCGGGTACCTCAGGGCTTCATGTGAACAATTCTCAATGCATAAAACACCCTGTTTTCTGTGGTAG ACCATAATTAGCTATTGCATGTAAAGCAATTTTGATTTTCTTGAACTTGTAAGCACCAAAGCATGTGTTTCCCAAAGGGGTATTACTGGGCTCTTAAGTA CCAAATGAAACCCTACTGTTTTACTTGGTTCCTTTTCCCTTTAGTAGGAGGACAGTGCTAACTGGAATTTTATAAGGAGTACCCTTTAAAATACAGAGAG TAAGTGAATTCATATTTTATATTCTAGAATGTTAACTGTGGTATTTCAGAAGACAGAGCTTGACTCAATGAATTGTAGAAATATAGGCTTGACTTAATTT TTGTAACTGAAAGGCTTTAGACTTAAAAAAATTTATTGTGCATCCTAAAATCTAAACCAATTATTAATGATCATTTATTGTAATGAGTTTGCATTTCAGC TTTATTCAATGCAGTACAAAATAGTTTTCTTTAAGCAGTCTTTTATCAATCAATGCTGCACTAGAAATAGATTCTCAAAAGTTACTAAACATTTTACTTT TTTTGTTTTTTAAAAGAAATGCAGATGAGTGTAAAACATCTGTTCTCAATTATGTTGATCTGTGTGCGCAGTACTGGAGCATTTACCCATTCATGTTGAG CCTCAAATGCTTGTTTTCTGGGGTCCACAAAAGACAGTTTTATACATTTTGAGTTGTTCATAAAGTTTGTCTTGTGATAGTCCTGGCACTTAAAGACAAA TTTTTCTGGTAGTAAAAGTTCAGATTTATTACTATGTCATGAAACACAGTACATTCAAATCAAACGGCAGTTTTCTTTCTAAGTAAATGATTTCCAGTCA TCTAAAAGGTGGGCAAGATGAGATAAAGACATTTTGATACAGTAATTGTTTTGGTTGGGTTTTCATGTCAGTTTATGTTTGACTAAAGCTCTCTTCATAT GCAGGTTTATAAATTTGTTAGGTCTGTTGTCCCATGATTAAACATGGAGTGCCTCCTCTCTGATTTAATATTCTGCAGGTCATTGTAACCTGCTAGGCAA AGTCACAACATTGCATTAAAGAGGTGATAGCTTTGCTAATATCACTGTTTTAAAGGACGTACAGTTAAAGGAATATTAAGTGGGAGAAAGCCTACAAGGC TTTTAGAATATTATCAGTATCTTCATTTCTGGTATTCAGATGTTATGTGATAAAACACATTTTTTTTGGCTTTCCCAGATACACTATATATTTGTTCAAG GGTAAATCTATAAAATGTATATACTTTATTTTGTGGTTTTGCTATTTATAAATTTAATGTTTTAACTGTTGCTCATTTATGGTTTGTTTTGGGTGGTGGT GTTCATCTGTATATCACCATGTTAATTTGTAATGGAAGTGCACTTCGTAGTGTATATTGTTACTGACATTAAAATACTTTATAGCATTGTCTCTGAGCAA AAGCTAGTATTTAATTGTACAAATGAATAAGCAAGTTACATGTTATTGTTTGCTCTTGACAGGGTAGGCCTCTTAAAAGAAAAAAAACAACTTGTTTTTT CTTTATGAATCCCCTATGCCAAACACATACCTTCCATGCATGACATGAGATCTGCAAACTGGATTTTAGCCACCGTATTTATTTAGTCAAAAAAATTGTC CATTGTAGCAGACCCGAAAACCTTTTTGCTGTGACATGAAACCATGTTATTCTTATCTTCTTAAAACACAGCCTGGGATGGAATGGCCATGGCATTTTTT TCAGAGAACATCCTTTATCTGCTATGACTGAATCCTTAGGAAATGTAAGCTATAACCCTTTGATTTTCAAGAACTACCGAATAAGTGTATGAAGAGGTGG TTTTTTAAAACTTCAAGTTGGAATTTTTATGAGGTCACTGTGTAATTTGAAGAATTGTGTGAGATTGTCATGATATAAATTCCTTTTAAGGACTGATAAA TAGAATGAAAAGTTTCCAGGTAGTTTAAAACTCCACAGGTCAGTTTCCTTTTCATTCCTGCTTCACTGTGGTTTATAAGCCTACGGGAGAGCACCGTTGC TCAGATGCTACTGTGAGCTTCCTGTCCGGTGTTAGAAAGTAACTAGTTAAAAGTTCATTTTAGAATGTATGGTTTTTGGGGATGAACTAAGAATTAGTTA TTAGTTCCAAAGGACTGAGAACCAATTTTAATATTTTCACATTTATAGGAAAGAAATTCATATGTCCCTGAAACTTCTAGGACAAAACCAAACAAGTAAG GAGGGAACTGTTGCAAAGCCATTTCATCGAGAAGGGGACAGAAGGAGAAATACACACATGTATACACAAACAGAATGGTTGAGAAAACGTTTTAATAAAA TGTGAGGGTTGTATGTGTGCGTGTATATATTTACACTTAACCTCTAAAATTCTCTTCTACAGTATCTCTGTTATGAATATGATGGAAAAGCAACATTTTG GTGGTGAGACTATTGTTAAAATAAATTTGAGAAAGACGAAAATTTTGTGAGTCTTGATAATTACAAGTCAACAGCTATCGAAAGTTAGCACAGCTTGTCT GTGGTGCTGTTTTTTTCCCCACTGCAGTGGACTTATGCTGTTTTCATGTTTAGAAACAAAAAGGTTTCATGTGATTCATGTGTAAGATGCACAGTATTTG ACATCCTGATTATGTAATCCCTATTCCATCTATCCAGTCTTACACTTATGGTTGGCCTCAAATCTATTGCATTTATGATAATGTATTATATCTAGTTGAG TTTAATATTTTTTTATTAGCCTGTAAATAAAGATGGCATCTTCTACATTAAAATGATATTGATCTCATTTTTTTAAATAAACATTTTGTTTCCTTGACGT TAAA

refseq_GOPC.F1 (forward primer)
refseq_GOPC.R1 (reverse primer)
Single exon skipping

Frame 0

GRWD*LSLPCVAAVAASASASLLLRFCDCAAGV NGAR*REVTECARARGGPLSPSSSLRARGAARVF SSRERPLTAPCRRAVHAQQQPEGAQGAPPAPWG PLAGYPCSGGWRCWRRSSTKLLWMWICSWERSI QTKRTSLMRGDRR*PA*APALHSFATKPSLCLKS TTSWRHSWWI*NLN*QKPKQRKLFWRKKYMISF YSCTLFSCSFMLKLVKVLTLVPLRQNCLAPLWR SWKESLRQTKKKK*KKHNLKLK*NC*EKRMKPFV DI*LFSRLKYMGRD*LPSTWIRNWQEGSNRYNC *DEI*RDLLMISFGTN*KLKYICIVTKL*SEPA EDVMT*NDQCKHHQAMIKIP*RKAKVLVQLEKFS SLRKIMKALAFQLQVGKNMVFQSSSLRSIRGNL LIDAEGCTLGMLFWQSTELT*GTQSIKKL*LFF LSREERLNLK*FMWLLKWILMMKT*SMKMRVDIV TVCTLMS*KEVVTLVLVAKTQVGKSKYYKDLIR RQ*LTHMKMETWALQVKLR*MTVLQN*MICTLC IIKNLIKLTISPDKIVNQTILNLGHWGRW*QRLQ NQGRLFVA*MKGGYLRASCEQFSMHKTPCFLW* TIISYCM*SNFDFLELVSTKACVSQRGITGLLS TK*NPTVLLGSFSL**EDSANWNFIRSTL*NTES K*IHILYSRMLTVVFQKTELDSMNCRNIGLT*F L*LKGFRLKKIYCAS*NLNQLLMIIYCNEFAFQ LYSMQYKIVFFKQSFINQCCTRNRFSKVTKHFTF FVF*KKCR*V*NICSQLC*SVCAVLEHLPIHVE PQMLVFWGPQKTVLYILSCS*SLSCDSPGT*RQ IFLVVKVQIYYYVMKHSTFKSNGSFLSK*MISSH LKGGQDEIKTF*YSNCFGWVFMSVYV*LKLSSY AGL*IC*VCCPMIKHGVPPL*FNILQVIVTC*A KSQHCIKEVIALLISLF*RTYS*RNIKWEKAYKA FRILSVSSFLVFRCYVIKHIFFGFPRYTIYLFK GKSIKCIYFILWFCYL*I*CFNCCSFMVCFGWW CSSVYHHVNL*WKCTS*CILLLTLKYFIALSLSK S*YLIVQMNKQVTCYCLLLTG*AS*KKKNNLFF LYESPMPNTYLPCMT*DLQTGF*PPYLFSQKNC PL*QTRKPFCCDMKPCYSYLLKTQPGMEWPWHFF QRTSFICYD*ILRKCKL*PFDFQELPNKCMKRW FFKTSSWNFYEVTV*FEELCEIVMI*IPFKD** IE*KVSR*FKTPQVSFLFIPASLWFISLRESTVA QMLL*ASCPVLESN*LKVHFRMYGFWG*TKN*L LVPKD*EPILIFSHL*ERNSYVPETSRTKPNK* GGNCCKAISSRRGQKEKYTHVYTNRMVEKTF**N VRVVCVRVYIYT*PLKFSSTVSLL*I*WKSNIL VVRLLLK*I*ERRKFCES**LQVNSYRKLAQLV CGAVFFPTAVDLCCFHV*KQKGFM*FMCKMHSI* HPDYVIPIPSIQSYTYGWPQIYCIYDNVLYLVE FNIFLLACK*RWHLLH*NDIDLIFLNKHFVSLT L

Frame 1

GGGTD*VFRVSPPLPPQLQPRYSCGSVTVLLAL TARGEGR*RSVPARAGVPSVPAVPFVRGGRRGS SAVGRGP*RRHVGGRSMPSSSRRGPRGRLLLRGG PWRGIHVPVAGGAGEGVRQSFCGCGSAPGRDRS RPSGHHL*GATEDDQPELLLCTALPQSPVCVSN QPQAGGTVGGSEI*TDRNPSRESCFGERST*SAF TAALYSAAASC*NWSKC*LWYH*GKIVWPLCGG AGKRA*GKQKRKNERSTT*S*SEIVEKRE*SPS *TYSCSPG*SIWGETSCQVLG*GTGRKGPTDTIA RTRYEGTCS**ALEPIRS*NTFASSQNCDPSLQ RT**LETTNASTTRP*SRFPKEKPRCWSN*KSS PP*GRS*RPWHFNYRWERTWCSNPHL*DPSGATC **MRRAARWGCYFGSQRS*PKGHKA*RSCNYSF SAERRD*I*SSLCGS*SGF***KRRV*R*EWTS LPFVP**VRRRW*PWC*LQRHKWGNQSITRI**E GSN*HT*KWRPGHCK*NSAR*RCFKIR*SAHSV S*KILLN*PYLQTRLLIRLF*IWGTGEDGDKDY KIRGGCLLPK*KAGTSGLHVNNSQCIKHPVFCGR P*LAIACKAILIFLNL*APKHVFPKGVLLGS*V PNETLLFYLVPFPFSRRTVLTGIL*GVPFKIQR VSEFIFYILEC*LWYFRRQSLTQ*IVEI*A*LNF CN*KALDLKKFIVHPKI*TNY**SFIVMSLHFS FIQCSTK*FSLSSLLSINAALEIDSQKLLNILL FLFFKRNADECKTSVLNYVDLCAQYWSIYPFMLS LKCLFSGVHKRQFYTF*VVHKVCLVIVLALKDK FFW**KFRFITMS*NTVHSNQTAVFFLSK*FPV I*KVGKMR*RHFDTVIVLVGFSCQFMFD*SSLHM QVYKFVRSVVP*LNMECLLSDLIFCRSL*PARQ SHNIALKR**LC*YHCFKGRTVKGILSGRKPTR LLEYYQYLHFWYSDVM**NTFFLAFPDTLYICSR VNL*NVYTLFCGFAIYKFNVLTVAHLWFVLGGG VHLYITMLICNGSALRSVYCY*H*NTL*HCL*A KASI*LYK*ISKLHVIVCS*QGRPLKRKKTTCFF FMNPLCQTHTFHA*HEICKLDFSHRIYLVKKIV HCSRPENLFAVT*NHVILIFLKHSLGWNGHGIF FREHPLSAMTESLGNVSYNPLIFKNYRISV*RGG FLKLQVGIFMRSLCNLKNCVRLS*YKFLLRTDK *NEKFPGSLKLHRSVSFSFLLHCGL*AYGRAPL LRCYCELPVRC*KVTS*KFILECMVFGDELRISY *FQRTENQF*YFHIYRKEIHMSLKLLGQNQTSK EGTVAKPFHREGDRRRNTHMYTQTEWLRKRFNK M*GLYVCVYIFTLNL*NSLLQYLCYEYDGKATFW W*DYC*NKFEKDENFVSLDNYKSTAIES*HSLS VVLFFSPLQWTYAVFMFRNKKVSCDSCVRCTVF DILIM*SLFHLSSLTLMVGLKSIAFMIMYYI*LS LIFFY*PVNKDGIFYIKMILISFF*INILFP*R *

Frame 2

EVGLTESSVCRRRCRLSFSLVTPAVL*LCCWR* RREVKGGDGVCPRARGSPQSQQFPSCAGGGEGL QQSGEALDGAMSAGGPCPAAAGGGPGGASCSVG APGGVSMFRWLEVLEKEFDKAFVDVDLLLGEIDP DQADITYEGRQKMTSLSSCFAQLCHKAQSVSQI NHKLEAQLVDLKSELTETQAEKVVLEKEVHDQL LQLHSIQLQLHAKTGQSADSGTIKAKLSGPSVEE LERELEANKKEKMKEAQLEAEVKLLRKENEALR RHIAVLQAEVYGARLAAKYLDKELAGRVQQIQL LGRDMKGPAHDKLWNQLEAEIHLHRHKTVIRACR GRNDLKRPMQAPPGHDQDSLKKSQGVGPIRKVL LLKEDHEGLGISITGGKEHGVPILISEIHPGQP ADRCGGLHVGDAILAVNGVNLRDTKHKEAVTILS QQRGEIEFEVVYVAPEVDSDDENVEYEDESGHR YRLYLDELEGGGNPGASCKDTSGEIKVLQGFNK KAVTDTHENGDLGTASETPLDDGASKLDDLHTLY HKKSY*IDHISRQDC*SDYSEFGALGKMVTKTT KSGEAVCCLNERRVPQGFM*TILNA*NTLFSVV DHN*LLHVKQF*FS*TCKHQSMCFPKGYYWALKY QMKPYCFTWFLFPLVGGQC*LEFYKEYPLKYRE *VNSYFIF*NVNCGISEDRA*LNEL*KYRLDLI FVTERL*T*KNLLCILKSKPIINDHLL**VCISA LFNAVQNSFL*AVFYQSMLH*K*ILKSY*TFYF FCFLKEMQMSVKHLFSIMLICVRSTGAFTHSC* ASNACFLGSTKDSFIHFELFIKFVL**SWHLKTN FSGSKSSDLLLCHETQYIQIKRQFSF*VNDFQS SKRWAR*DKDILIQ*LFWLGFHVSLCLTKALFI CRFINLLGLLSHD*TWSASSLI*YSAGHCNLLGK VTTLH*RGDSFANITVLKDVQLKEY*VGESLQG F*NIISIFISGIQMLCDKTHFFWLSQIHYIFVQ G*IYKMYILYFVVLLFINLMF*LLLIYGLFWVVV FICISPC*FVMEVHFVVYIVTDIKILYSIVSEQ KLVFNCTNE*ASYMLLFALDRVGLLKEKKQLVF SL*IPYAKHIPSMHDMRSANWILATVFI*SKKLS IVADPKTFLL*HETMLFLSS*NTAWDGMAMAFF SENILYLL*LNP*EM*AITL*FSRTTE*VYEEV VF*NFKLEFL*GHCVI*RIV*DCHDINSF*GLIN RMKSFQVV*NSTGQFPFHSCFTVVYKPTGEHRC SDATVSFLSGVRK*LVKSSF*NVWFLGMN*ELV ISSKGLRTNFNIFTFIGKKFICP*NF*DKTKQVR RELLQSHFIEKGTEGEIHTCIHKQNG*ENVLIK CEGCMCACIYLHLTSKILFYSISVMNMMEKQHF GGETIVKINLRKTKIL*VLIITSQQLSKVSTACL WCCFFPHCSGLMLFSCLETKRFHVIHV*DAQYL TS*LCNPYSIYPVLHLWLASNLLHL**CIISS* V*YFFISL*IKMASSTLK*Y*SHFFK*TFCFLDV K