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Sequences

Sequence NM_004501

CTCGCGCCAGGCGAGTCTCCGCGTCTCCCTCGCGAACTCGGTGAAAGGAATTGGCGCCGTTCGACACCAGGCGGATCCGCTCTGCAGCACGAACCCATCT CCAGCCGCAGCCGCAGCCGCCGCCCGGGCCGAGGAGCAGCCGCAGCAGCCGCCACCAGTGGCCGAGTGAGCGGAGCCGAGTTTGAGGCAGCGCCTAGCGG TGAATCGGGGCCCTCACCATGAGTTCCTCGCCTGTTAATGTAAAAAAGCTGAAGGTGTCGGAGCTGAAAGAGGAGCTCAAGAAGCGACGCCTTTCTGACA AGGGTCTCAAGGCCGAGCTCATGGAGCGACTCCAGGCTGCGCTGGACGACGAGGAGGCCGGGGGCCGCCCCGCCATGGAGCCCGGGAACGGCAGCCTAGA CCTGGGCGGGGATTCCGCTGGGCGCTCGGGAGCAGGCCTCGAGCAGGAGGCCGCGGCCGGCGGCGATGAAGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA GGAATCTCCGCTCTGGACGGCGACCAGATGGAGCTAGGAGAGGAGAACGGGGCCGCGGGGGCGGCCGACTCGGGCCCGATGGAGGAGGAGGAGGCCGCCT CGGAAGACGAGAACGGCGACGATCAGGGTTTCCAGGAAGGGGAAGATGAGCTCGGGGACGAAGAGGAAGGCGCGGGCGACGAGAACGGGCACGGGGAGCA GCAGCCTCAACCGCCGGCGACGCAGCAGCAACAGCCCCAACAGCAGCGCGGGGCCGCCAAGGAGGCCGCGGGGAAGAGCAGCGGCCCCACCTCGCTGTTC GCGGTGACGGTGGCGCCGCCCGGGGCGAGGCAGGGCCAGCAGCAGGCGGGAGGGGACGGCAAAACAGAACAGAAAGGCGGAGATAAAAAGAGGGGTGTTA AAAGACCACGAGAAGATCATGGCCGTGGATATTTTGAGTACATTGAAGAGAACAAGTATAGCAGAGCCAAATCTCCTCAGCCACCTGTTGAAGAAGAAGA TGAACACTTCGATGACACAGTGGTTTGTCTTGATACTTATAATTGTGATCTACATTTTAAAATATCAAGAGATCGTCTCAGTGCTTCTTCCCTTACAATG GAGAGTTTTGCTTTTCTTTGGGCTGGAGGAAGAGCATCCTATGGTGTGTCAAAAGGCAAAGTGTGTTTTGAGATGAAGGTTACAGAGAAGATCCCAGTAA GGCATTTATATACAAAAGATATTGACATACATGAAGTTCGTATTGGCTGGTCACTAACTACAAGTGGAATGTTACTTGGTGAAGAAGAATTTTCTTATGG GTATTCTCTAAAAGGAATAAAAACATGCAACTGTGAGACTGAAGATTATGGAGAAAAGTTTGATGAAAATGATGTGATTACATGTTTTGCTAACTTTGAA AGTGATGAAGTAGAACTCTCGTATGCTAAGAATGGACAAGATCTTGGCGTTGCCTTCAAAATCAGTAAGGAAGTTCTTGCTGGACGGCCACTGTTCCCGC ATGTTCTCTGCCACAACTGTGCAGTTGAATTTAATTTTGGTCAGAAGGAAAAGCCATATTTTCCAATACCTGAAGAGTATACTTTCATCCAGAACGTCCC CTTAGAGGATCGAGTTAGAGGACCAAAGGGGCCTGAAGAGAAGAAAGATTGTGAAGTTGTGATGATGATTGGCTTGCCAGGAGCTGGAAAAACTACCTGG GTTACTAAACATGCAGCAGAAAATCCAGGGAAATATAACATTCTTGGCACAAATACTATTATGGATAAGATGATGGTGGCAGGTTTTAAGAAGCAAATGG CAGATACTGGAAAACTGAACACACTGTTGCAGAGAGCCCCCCAGTGTCTTGGGAAATTTATTGAGATTGCTGCCCGAAAGAAGCGAAATTTTATTCTGGA TCAGACAAATGTGTCTGCTGCTGCCCAGAGGAGAAAAATGTGCCTGTTTGCAGGCTTCCAGCGAAAAGCTGTTGTAGTTTGCCCAAAAGATGAAGACTAT AAGCAAAGAACACAGAAGAAAGCAGAAGTAGAGGGGAAAGACCTACCAGAACATGCGGTCCTCAAAATGAAAGGAAACTTTACCCTCCCAGAGGTAGCTG AGTGCTTTGATGAAATAACCTATGTTGAACTTCAGAAGGAAGAAGCCCAAAAACTCTTGGAGCAATATAAGGAAGAAAGCAAAAAGGCTCTTCCACCAGA AAAGAAACAGAACACTGGCTCAAAGAAAAGCAATAAAAATAAGAGTGGCAAGAACCAGTTTAACAGAGGTGGTGGCCATAGAGGACGTGGAGGATTCAAT ATGCGTGGTGGAAATTTCAGAGGAGGAGCCCCTGGGAATCGTGGCGGATATAATAGGAGGGGCAACATGCCACAGAGAGGTGGTGGCGGTGGAGGAAGTG GTGGAATCGGCTATCCATACCCTCGTGCCCCTGTTTTTCCTGGCCGTGGTAGTTACTCAAACAGAGGGAACTACAACAGAGGTGGAATGCCCAACAGAGG GAACTACAACCAGAACTTCAGAGGACGAGGAAACAATCGTGGCTACAAAAATCAATCTCAGGGCTACAACCAGTGGCAGCAGGGTCAATTCTGGGGTCAG AAGCCATGGAGTCAGCATTATCACCAAGGATATTATTGAATACCCAAATAAAACGAACTGATACATATTTCTCCAAAACCTTCACAAGAAGTCGACTGTT TTCTTTAGTAGGCTAACTTTTTAAACATTCCACAAGAGGAAGTGCCTGCGGGTTCCTTTTTTAGAAGCTTTGTGGGTTGATTTTTTTTCTTTTCTTTTTT GTACATTTTTAATTGCAGTTTAAAAGTGAATCGTAAGAGAACCTCAGCATTGTGCACGATAAGAGAATGTGTCAGTATTTCAGGGTTCTACATTTTATCT GTAAAATGTGACTTTTTTTTTTTTTTATCACAACAGAAGTAAAATGTTGCTTTGTACCTGGTGTCTTTTATTAAGAATTTACTCCCCCCATTTCTCACAG AGAATAACAGTCGGGAGTCATTGTCACAATATAATAGAAATGTTAGCAACCAGATTCATGTAAGGACTAAGTGGTCCTCATGAATTGCATTAAGACTCTG TACTGCTCATATTACACTCCATCCTCTCTGTAGTTTGCTGGGTAGTGGAGGGGGTAAGCTAAATCATAGTTTCTGACAATAACTGGGAAGGTTTTTTCTT AAAATAACAATGGAATTGGTATAATTGGGATTGAAAACTAAAACTTGGAACTAAGATAGAGAAGATGGAGTGTATGTAGAAGGGCTGTTAAAAATGTAAA ACTTGGTTGCATTATTTGTGGAGGCTCAAACTTGTGAAGGTTAATACCATAATTTTTCCATTTGTTCTGCATTTTGATTCTGAAAAGAAAGCTGGCTTTG CCCATTTCTTATTAAAAAAACTTGTTGTAAATCCAGTTGTCTAATGGGATCTATATGAAGTTAGCCATGTCTGTATGCCCTTCTCCCACAAAATACTGTA TAACTAGTGTGCTTGTAGTAGTTAACTCCACCATCTTTGTAAGCTAATGAAATTGTGAGTCACCCATTTATATCTTAATTTTTAATCATGTCAGTTCTTG AATGGGTATCTCCTTAGCCTGCTGATTTCTTTTTCTTTCTAAAGAAAGTGGGTGGAGAAATTAATTTAGACGTTTGTTTGCAATAAAAAGAATTCATTTT ACTCTTGTTTTGGGATTCTCGCCATCAAGGTTCAAAATCCCTTTATATAACTCCCAAGAGGAGAAATTTATTAAGTGTGTGCTTTCTGGACAGCTTATTC TTTACTCTGCATAGAACATTTAGGTTTTAAAAACTTAAATGTATACTGACAATTGATACATAATTATGAAGTAAAGTTGAATTCTTCCCTTCCCCTCCCC CCCAGACAACTTTTAACATATTTAATGAGGGGAAAAGGTACTGGCTGGGAGAAGTTAACACTGAGTTTATCATCTTTACAGAATGCTAATGCTGTCCTCA ACTGATTATTTTATATACATATATATGATACATGAAACTCTGGGATCAGATGCTTTTAGAAGCCATCATGCAAGCCAGTCATTGATGTCACTGCTACACA ACACTGCTAACTTGACTGTAGCTATGTAATAACATTAGATCCCCTAATTGTAATTATATTGGGTTTGCACAGAACACTTTAATCTTCCCCTCACCAATGT GAAGTGAGGAATCAGGAGTCAAACTGTAGAACTAAAATTTGACTTCAGTCTAGCGTTTCCTTGGTGTTTTTAGGTTGCTTTGGTAAGTTTAGGTTTGCTA TATTTCTGATTGCTTAGAATTTTGTTTTAGCCCTTTAAAATCAGATCATAAATATGAATTCATACTTCTAAGGAATTTTCTTGCTATAAGCTGGAGTTTA GGTGATGTATAGGTTCAGTTGAGACATTTTTGGAACAGGCAAATCCTTAGTTAACATAAGATATTTAACAGTTGAAGATAGTGTCATGGATTTTTATCTT TTTTAGCAAGTAATGCTAAGAACCACTGGCCTGAGCTACTACTCTTCAGTATACATTATTAGGATTGCATAGACTTACTAGAGGAACAGTTTCAGGTTTT GATGCTAATCAGTGTTGTGTCCTAAAGTTGTCCTTTGTGCCTTTAAAAAGTTTTGGATATATCTTCTAGTTTAAAATTGCTTATTAAGGAATTCATTTTA TAATTGCAGTGGGAAAGTAATGGTCAAGTAACACTAGGTAGACTATCATGCCTGTTTAGCCCAGAGAATTTGGGGGGAGAGAGAATAGATAAAAATGGCA CCCAGAAAAATGTTAAAATCTTTAGTCAAGACTAGAATTAATACAATTGTCTACACTTGTATGGCAGAAATAACCTTATAAAGTGTTTAAGGAATTCAGA GAAGGGAATGTACCAAATAAGCAACAGGGAGAAAATTAGGTAAGAAGTAAGATACGAACGAGAAACCTGATTTATTGCTCATCCTTCCCTTGCCTCCCTA ATGGCAAGCAAAACTCTGAACATCTGAAAAGGATGTAGTTCTGGACAAATCCTGACTACCCAGAGGAAACTCACTGTGAGATTGCTGTTGATTTGAAGGG TGCTTTCACTAAGGTTATATTTTAAAGTAGAATAACACATGCTGAGTGTAAACTGGCTTTGGATTGGTCAGCTGCAGTAGTACAAAAACAGCATAGAATT TGAGAAAACTAAAACTGCTATGAGATAGCTATGAGAAAACTAAAACTGCTATGAGATAGAAATGATGTAAAATTATGTGGAAAGTTTTCCCTCATATACT CACATACAGCCTTTGAAGGGCTCTGGCTCTGACCGGTTGATGGCCTTGAGCGAGATGAAATCATGAAATTGAGTCAAATCAATTTGACATTGAAATGACA AGAGGAAACTCTTAAATACATAAAAACAAGCTCTCATTTGCCTAGGATAGATACTGTCTTAAAAATAAAGACTGAACCTAGATGTTCTGAGCACTAGCAA CAAGGTATTTTAACAAGTTTAAAGGAATTCTCTGAAAAAGTTATAAAATTATTCTAGGAAACATAACCATAATAGTGTTTTAAGGGACTTTCACCTGGGG ATTTTATATTCATGAACAGAGTGTATTCTGTATTTAAAATGTCTCATTTGTGGGAATTGGATGACATGTTTTTTGATAAATTTATTCACAATATAAATTG ACTTTTTATTCTAGGACCATGTGAATAATGGGTTCCATTGCACAAATACAAATATTTTAATAGCTTCTTAGGCAGTGGTGTAGACATCTTGGATATAAAT AATTGTAGATCTTGTATATTTGATTTTTAAAAAACTAGAATAAACAGAGAGGCATAAACATATCTTAGAGTCCAAGTGGTAGTGTTTAGCATTGGATATA ATAAATGGATGTTTTACAAAGTGTTTCCATAATTCTCTTCCTATACATAAATGTCTTGTTTTCAAAAGTGGATGGAACTTGGCTGGGTGTGGTGGCTCAC GCCTGTAATCCTAGCACTTTGGGAGGCCAAGGCGGGAGGATCACTTGAGCTCAGGAGTTTGAGACCATCCTGGGCAACATAGTGAGACCTGGTCTCTTGA AAAAAAAAAAGTGGATGGAACTTGTAGCAGAGAATTTTATCTACTTCTCAACCTGCTTCAGAATACCCATTTGAGATGTTCCCCTGGAAAGATGAACACA ATACTGCATCTGAAGCCATTTCTTCCCACCTAACATTCTTAAAATGATTAGAGTCTAAACTTTGTCATTCATTCCTAATTCTGGAGCTCTGAGGTTGAGG TGTTCAGAGTTTGGTGAATAATTGGGTTTAAGTTTTAACATTTTAGTAATAATAAAAGCAAACACATACATGTTAAGGCCTGACAATAGGTTGCAATACC CATGCATTGGGACTCATACCCAGCATAAATGGTGAGGGACTGAACATTAGTGCTTTGAGCAAGAATTGGTTAACTACCTGAGATCTCTAAAACAGTAATT TGAATTACTAATACATAAACCACAAGTCTCTTCGAATTGTTAATTGCCTAAATTTACCCTAAAACTTAGTTAACGCTGCAGTGCCTTTATTAAAGCTTTT TTTTGGGGGGGGGTGTGGGCACAGCTACTCCATAACTTTAAATTTTAAAGCATGAAGGTGATCTAGCTAGTGTTAGTGCTTGAGTTGGTAGTTACATAGG CTGCTCTTGAATCGTCCTGTTTTCTTTGCCTAGTATTAGCACCACAGGTACATATTTGTAAAATAAGCATTAAAAGTACTTTGTCCAGC

refseq_HNRPU.F2 (forward primer)
refseq_HNRPU.R2 (reverse primer)
Alternative donor

Frame 0

LAPGESPRLPRELGERNWRRSTPGGSALQHEPI SSRSRSRRPGRGAAAAAATSGRVSGAEFEAAPSG ESGPSP*VPRLLM*KS*RCRS*KRSSRSDAFLT RVSRPSSWSDSRLRWTTRRPGAAPPWSPGTAA* TWAGIPLGAREQASSRRPRPAAMKRRRKRKRRRK ESPLWTATRWS*ERRTGPRGRPTRARWRRRRPP RKTRTATIRVSRKGKMSSGTKRKARATRTGTGS SSLNRRRRSSNSPNSSAGPPRRPRGRAAAPPRCS R*RWRRPGRGRASSRREGTAKQNRKAEIKRGVL KDHEKIMAVDILSTLKRTSIAEPNLLSHLLKKK MNTSMTQWFVLILIIVIYILKYQEIVSVLLPLQW RVLLFFGLEEEHPMVCQKAKCVLR*RLQRRSQ* GIYIQKILTYMKFVLAGH*LQVECYLVKKNFLM GIL*KE*KHATVRLKIMEKSLMKMM*LHVLLTLK VMK*NSRMLRMDKILALPSKSVRKFLLDGHCSR MFSATTVQLNLILVRRKSHIFQYLKSILSSRTS P*RIELEDQRGLKRRKIVKL***LACQELEKLPG LLNMQQKIQGNITFLAQILLWIR*WWQVLRSKW QILEN*THCCREPPSVLGNLLRLLPERSEILFW IRQMCLLLPRGEKCACLQASSEKLL*FAQKMKTI SKEHRRKQK*RGKTYQNMRSSK*KETLPSQR*L SALMK*PMLNFRRKKPKNSWSNIRKKAKRLFHQ KRNRTLAQRKAIKIRVARTSLTEVVAIEDVEDSI CVVEISEEEPLGIVADIIGGATCHREVVAVEEV VESAIHTLVPLFFLAVVVTQTEGTTTEVECPTE GTTTRTSEDEETIVATKINLRATTSGSRVNSGVR SHGVSIITKDIIEYPNKTN*YIFLQNLHKKSTV FFSRLTF*TFHKRKCLRVPFLEALWVDFFSFLF CTFLIAV*K*IVREPQHCAR*ENVSVFQGSTFYL *NVTFFFFYHNRSKMLLCTWCLLLRIYSPHFSQ RITVGSHCHNIIEMLATRFM*GLSGPHELH*DS VLLILHSILSVVCWVVEGVS*IIVSDNNWEGFFL K*QWNWYNWD*KLKLGTKIEKMECM*KGC*KCK TWLHYLWRLKLVKVNTIIFPFVLHFDSEKKAGF AHFLLKKLVVNPVV*WDLYEVSHVCMPFSHKILY N*CACSS*LHHLCKLMKL*VTHLYLNF*SCQFL NGYLLSLLISFSF*RKWVEKLI*TFVCNKKNSF YSCFGILAIKVQNPFI*LPRGEIY*VCAFWTAYS LLCIEHLGFKNLNVY*QLIHNYEVKLNSSLPLP PRQLLTYLMRGKGTGWEKLTLSLSSLQNANAVL N*LFYIHIYDT*NSGIRCF*KPSCKPVIDVTATQ HC*LDCSYVITLDPLIVIILGLHRTL*SSPHQC EVRNQESNCRTKI*LQSSVSLVFLGCFGKFRFA IFLIA*NFVLAL*NQIINMNSYF*GIFLL*AGV* VMYRFS*DIFGTGKSLVNIRYLTVEDSVMDFYL F*QVMLRTTGLSYYSSVYIIRIA*TY*RNSFRF *C*SVLCPKVVLCAFKKFWIYLLV*NCLLRNSFY NCSGKVMVK*H*VDYHACLAQRIWGERE*IKMA PRKMLKSLVKTRINTIVYTCMAEITL*SV*GIQ RRECTK*ATGRKLGKK*DTNEKPDLLLILPLPP* WQAKL*TSEKDVVLDKS*LPRGNSL*DCC*FEG CFH*GYILK*NNTC*V*TGFGLVSCSSTKTA*N LRKLKLL*DSYEKTKTAMR*K*CKIMWKVFPHIL TYSL*RALALTG*WP*AR*NHEIESNQFDIEMT RGNS*IHKNKLSFA*DRYCLKNKD*T*MF*ALA TRYFNKFKGIL*KSYKIILGNITIIVF*GTFTWG FYIHEQSVFCI*NVSFVGIG*HVF**IYSQYKL TFYSRTM*IMGSIAQIQIF**LLRQWCRHLGYK *L*ILYI*FLKN*NKQRGINIS*SPSGSV*HWI* *MDVLQSVSIILFLYINVLFSKVDGTWLGVVAH ACNPSTLGGQGGRIT*AQEFETILGNIVRPGLL KKKKWMELVAENFIYFSTCFRIPI*DVPLER*TQ YCI*SHFFPPNILKMIRV*TLSFIPNSGALRLR CSEFGE*LGLSFNILVIIKANTYMLRPDNRLQY PCIGTHTQHKW*GTEH*CFEQELVNYLRSLKQ*F ELLIHKPQVSSNC*LPKFTLKLS*RCSAFIKAF FWGGVWAQLLHNFKF*SMKVI*LVLVLELVVT* AALESSCFLCLVLAPQVHICKISIKSTLSS

Frame 1

SRQASLRVSLANSVKGIGAVRHQADPLCSTNPS PAAAAAAARAEEQPQQPPPVAE*AEPSLRQRLA VNRGPHHEFLAC*CKKAEGVGAERGAQEATPF*Q GSQGRAHGATPGCAGRRGGRGPPRHGARERQPR PGRGFRWALGSRPRAGGRGRRR*RGGGRGRGGG RNLRSGRRPDGARRGERGRGGGRLGPDGGGGGRL GRRERRRSGFPGRGR*ARGRRGRRGRRERARGA AASTAGDAAATAPTAARGRQGGRGEEQRPHLAV RGDGGAARGEAGPAAGGRGRQNRTERRR*KEGC* KTTRRSWPWIF*VH*REQV*QSQISSATC*RRR *TLR*HSGLS*YL*L*STF*NIKRSSQCFFPYN GEFCFSLGWRKSILWCVKRQSVF*DEGYREDPSK AFIYKRY*HT*SSYWLVTNYKWNVTW*RRIFLW VFSKRNKNMQL*D*RLWRKV**K*CDYMFC*L* K**SRTLVC*EWTRSWRCLQNQ*GSSCWTATVPA CSLPQLCS*I*FWSEGKAIFSNT*RVYFHPERP LRGSS*RTKGA*REERL*SCDDDWLARSWKNYL GY*TCSRKSREI*HSWHKYYYG*DDGGRF*EANG RYWKTEHTVAESPPVSWEIY*DCCPKEAKFYSG SDKCVCCCPEEKNVPVCRLPAKSCCSLPKR*RL *AKNTEESRSRGERPTRTCGPQNERKLYPPRGS* VL**NNLC*TSEGRSPKTLGAI*GRKQKGSSTR KETEHWLKEKQ*K*EWQEPV*QRWWP*RTWRIQ YAWWKFQRRSPWESWRI**EGQHATERWWRWRKW WNRLSIPSCPCFSWPW*LLKQRELQQRWNAQQR ELQPELQRTRKQSWLQKSISGLQPVAAGSILGS EAMESALSPRILLNTQIKRTDTYFSKTFTRSRLF SLVG*LFKHSTRGSACGFLF*KLCGLIFFLFFF VHF*LQFKSES*ENLSIVHDKRMCQYFRVLHFI CKM*LFFFFITTEVKCCFVPGVFY*EFTPPISHR E*QSGVIVTI**KC*QPDSCKD*VVLMNCIKTL YCSYYTPSSL*FAG*WRG*AKS*FLTITGKVFS *NNNGIGIIGIEN*NLELR*RRWSVCRRAVKNVK LGCIICGGSNL*RLIP*FFHLFCILILKRKLAL PISY*KNLL*IQLSNGIYMKLAMSVCPSPTKYC ITSVLVVVNSTIFVS**NCESPIYILIFNHVSS* MGISLAC*FLFLSKESGWRN*FRRLFAIKRIHF TLVLGFSPSRFKIPLYNSQEEKFIKCVLSGQLI LYSA*NI*VLKT*MYTDN*YIIMK*S*ILPFPSP PDNF*HI**GEKVLAGRS*H*VYHLYRMLMLSS TDYFIYIYMIHETLGSDAFRSHHASQSLMSLLH NTANLTVAM**H*IP*L*LYWVCTEHFNLPLTNV K*GIRSQTVELKFDFSLAFPWCF*VALVSLGLL YF*LLRILF*PFKIRS*I*IHTSKEFSCYKLEF R*CIGSVETFLEQANP*LT*DI*QLKIVSWIFIF FSK*C*EPLA*ATTLQYTLLGLHRLTRGTVSGF DANQCCVLKLSFVPLKSFGYIF*FKIAY*GIHF IIAVGK*WSSNTR*TIMPV*PREFGGRENR*KWH PEKC*NL*SRLELIQLSTLVWQK*PYKVFKEFR EGNVPNKQQGEN*VRSKIRTRNLIYCSSFPCLP NGKQNSEHLKRM*FWTNPDYPEETHCEIAVDLKG AFTKVIF*SRITHAECKLALDWSAAVVQKQHRI *EN*NCYEIAMRKLKLL*DRNDVKLCGKFSLIY SHTAFEGLWL*PVDGLERDEIMKLSQINLTLK*Q EETLKYIKTSSHLPRIDTVLKIKTEPRCSEH*Q QGILTSLKEFSEKVIKLF*ET*P**CFKGLSPG DFIFMNRVYSVFKMSHLWELDDMFFDKFIHNIN* LFILGPCE*WVPLHKYKYFNSFLGSGVDILDIN NCRSCIFDF*KTRINREA*TYLRVQVVVFSIGY NKWMFYKVFP*FSSYT*MSCFQKWMELGWVWWLT PVILALWEAKAGGSLELRSLRPSWAT**DLVS* KKKSGWNL*QRILSTSQPASEYPFEMFPWKDEH NTASEAISSHLTFLK*LESKLCHSFLILEL*G*G VQSLVNNWV*VLTF****KQTHTC*GLTIGCNT HALGLIPSINGEGLNISALSKNWLTT*DL*NSN LNY*YINHKSLRIVNCLNLP*NLVNAAVPLLKLF FGGGCGHSYSITLNFKA*R*SS*C*CLSW*LHR LLLNRPVFFA*Y*HHRYIFVK*ALKVLCP

Frame 2

RARRVSASPSRTR*KELAPFDTRRIRSAARTHL QPQPQPPPGPRSSRSSRHQWPSERSRV*GSA*R *IGALTMSSSPVNVKKLKVSELKEELKKRRLSD KGLKAELMERLQAALDDEEAGGRPAMEPGNGSLD LGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEE GISALDGDQMELGEENGAAGAADSGPMEEEEAA SEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQ QPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLF AVTVAPPGARQGQQQAGGDGKTEQKGGDKKRGV KRPREDHGRGYFEYIEENKYSRAKSPQPPVEEED EHFDDTVVCLDTYNCDLHFKISRDRLSASSLTM ESFAFLWAGGRASYGVSKGKVCFEMKVTEKIPV RHLYTKDIDIHEVRIGWSLTTSGMLLGEEEFSYG YSLKGIKTCNCETEDYGEKFDENDVITCFANFE SDEVELSYAKNGQDLGVAFKISKEVLAGRPLFP HVLCHNCAVEFNFGQKEKPYFPIPEEYTFIQNVP LEDRVRGPKGPEEKKDCEVVMMIGLPGAGKTTW VTKHAAENPGKYNILGTNTIMDKMMVAGFKKQM ADTGKLNTLLQRAPQCLGKFIEIAARKKRNFILD QTNVSAAAQRRKMCLFAGFQRKAVVVCPKDEDY KQRTQKKAEVEGKDLPEHAVLKMKGNFTLPEVA ECFDEITYVELQKEEAQKLLEQYKEESKKALPPE KKQNTGSKKSNKNKSGKNQFNRGGGHRGRGGFN MRGGNFRGGAPGNRGGYNRRGNMPQRGGGGGGS GGIGYPYPRAPVFPGRGSYSNRGNYNRGGMPNRG NYNQNFRGRGNNRGYKNQSQGYNQWQQGQFWGQ KPWSQHYHQGYY*IPK*NELIHISPKPSQEVDC FL**ANFLNIPQEEVPAGSFFRSFVG*FFFFSFL YIFNCSLKVNRKRTSALCTIRECVSISGFYILS VKCDFFFFLSQQK*NVALYLVSFIKNLLPPFLT ENNSRESLSQYNRNVSNQIHVRTKWSS*IALRLC TAHITLHPLCSLLGSGGGKLNHSF*Q*LGRFFL KITMELV*LGLKTKTWN*DREDGVYVEGLLKM* NLVALFVEAQTCEG*YHNFSICSAF*F*KESWLC PFLIKKTCCKSSCLMGSI*S*PCLYALLPQNTV *LVCL**LTPPSL*ANEIVSHPFIS*FLIMSVL EWVSP*PADFFFFLKKVGGEINLDVCLQ*KEFIL LLFWDSRHQGSKSLYITPKRRNLLSVCFLDSLF FTLHRTFRF*KLKCILTIDT*L*SKVEFFPSPP PQTTFNIFNEGKRYWLGEVNTEFIIFTEC*CCPQ LIILYTYI*YMKLWDQMLLEAIMQASH*CHCYT TLLT*L*LCNNIRSPNCNYIGFAQNTLIFPSPM *SEESGVKL*N*NLTSV*RFLGVFRLLW*V*VCY ISDCLEFCFSPLKSDHKYEFILLRNFLAISWSL GDV*VQLRHFWNRQILS*HKIFNS*R*CHGFLS FLASNAKNHWPELLLFSIHY*DCIDLLEEQFQVL MLISVVS*SCPLCL*KVLDISSSLKLLIKEFIL *LQWESNGQVTLGRLSCLFSPENLGGERIDKNG TQKNVKIFSQD*N*YNCLHLYGRNNLIKCLRNSE KGMYQISNREKIR*EVRYERET*FIAHPSLASL MASKTLNI*KGCSSGQILTTQRKLTVRLLLI*R VLSLRLYFKVE*HMLSVNWLWIGQLQ*YKNSIEF EKTKTAMR*L*EN*NCYEIEMM*NYVESFPSYT HIQPLKGSGSDRLMALSEMKS*N*VKSI*H*ND KRKLLNT*KQALICLG*ILS*K*RLNLDVLSTSN KVF*QV*RNSLKKL*NYSRKHNHNSVLRDFHLG ILYS*TECILYLKCLICGNWMTCFLINLFTI*I DFLF*DHVNNGFHCTNTNILIAS*AVV*TSWI*I IVDLVYLIFKKLE*TERHKHILESKW*CLALDI INGCFTKCFHNSLPIHKCLVFKSGWNLAGCGGS RL*S*HFGRPRREDHLSSGV*DHPGQHSETWSLE KKKVDGTCSREFYLLLNLLQNTHLRCSPGKMNT ILHLKPFLPT*HS*ND*SLNFVIHS*FWSSEVE VFRVW*IIGFKF*HFSNNKSKHIHVKA*Q*VAIP MHWDSYPA*MVRD*TLVL*ARIG*LPEISKTVI *ITNT*TTSLFELLIA*IYPKT*LTLQCLY*SF FLGGGVGTATP*L*ILKHEGDLASVSA*VGSYIG CS*IVLFSLPSISTTGTYL*NKH*KYFVQ

Sequence NM_031844

CTCGCGCCAGGCGAGTCTCCGCGTCTCCCTCGCGAACTCGGTGAAAGGAATTGGCGCCGTTCGACACCAGGCGGATCCGCTCTGCAGCACGAACCCATCT CCAGCCGCAGCCGCAGCCGCCGCCCGGGCCGAGGAGCAGCCGCAGCAGCCGCCACCAGTGGCCGAGTGAGCGGAGCCGAGTTTGAGGCAGCGCCTAGCGG TGAATCGGGGCCCTCACCATGAGTTCCTCGCCTGTTAATGTAAAAAAGCTGAAGGTGTCGGAGCTGAAAGAGGAGCTCAAGAAGCGACGCCTTTCTGACA AGGGTCTCAAGGCCGAGCTCATGGAGCGACTCCAGGCTGCGCTGGACGACGAGGAGGCCGGGGGCCGCCCCGCCATGGAGCCCGGGAACGGCAGCCTAGA CCTGGGCGGGGATTCCGCTGGGCGCTCGGGAGCAGGCCTCGAGCAGGAGGCCGCGGCCGGCGGCGATGAAGAGGAGGAGGAAGAGGAAGAGGAGGAGGAA GGAATCTCCGCTCTGGACGGCGACCAGATGGAGCTAGGAGAGGAGAACGGGGCCGCGGGGGCGGCCGACTCGGGCCCGATGGAGGAGGAGGAGGCCGCCT CGGAAGACGAGAACGGCGACGATCAGGGTTTCCAGGAAGGGGAAGATGAGCTCGGGGACGAAGAGGAAGGCGCGGGCGACGAGAACGGGCACGGGGAGCA GCAGCCTCAACCGCCGGCGACGCAGCAGCAACAGCCCCAACAGCAGCGCGGGGCCGCCAAGGAGGCCGCGGGGAAGAGCAGCGGCCCCACCTCGCTGTTC GCGGTGACGGTGGCGCCGCCCGGGGCGAGGCAGGGCCAGCAGCAGGCGGGAGGTAAGAAGAAGGCGGAAGGCGGCGGAGGCGGCGGTCGCCCCGGGGCTC CGGCGGCGGGGGACGGCAAAACAGAACAGAAAGGCGGAGATAAAAAGAGGGGTGTTAAAAGACCACGAGAAGATCATGGCCGTGGATATTTTGAGTACAT TGAAGAGAACAAGTATAGCAGAGCCAAATCTCCTCAGCCACCTGTTGAAGAAGAAGATGAACACTTCGATGACACAGTGGTTTGTCTTGATACTTATAAT TGTGATCTACATTTTAAAATATCAAGAGATCGTCTCAGTGCTTCTTCCCTTACAATGGAGAGTTTTGCTTTTCTTTGGGCTGGAGGAAGAGCATCCTATG GTGTGTCAAAAGGCAAAGTGTGTTTTGAGATGAAGGTTACAGAGAAGATCCCAGTAAGGCATTTATATACAAAAGATATTGACATACATGAAGTTCGTAT TGGCTGGTCACTAACTACAAGTGGAATGTTACTTGGTGAAGAAGAATTTTCTTATGGGTATTCTCTAAAAGGAATAAAAACATGCAACTGTGAGACTGAA GATTATGGAGAAAAGTTTGATGAAAATGATGTGATTACATGTTTTGCTAACTTTGAAAGTGATGAAGTAGAACTCTCGTATGCTAAGAATGGACAAGATC TTGGCGTTGCCTTCAAAATCAGTAAGGAAGTTCTTGCTGGACGGCCACTGTTCCCGCATGTTCTCTGCCACAACTGTGCAGTTGAATTTAATTTTGGTCA GAAGGAAAAGCCATATTTTCCAATACCTGAAGAGTATACTTTCATCCAGAACGTCCCCTTAGAGGATCGAGTTAGAGGACCAAAGGGGCCTGAAGAGAAG AAAGATTGTGAAGTTGTGATGATGATTGGCTTGCCAGGAGCTGGAAAAACTACCTGGGTTACTAAACATGCAGCAGAAAATCCAGGGAAATATAACATTC TTGGCACAAATACTATTATGGATAAGATGATGGTGGCAGGTTTTAAGAAGCAAATGGCAGATACTGGAAAACTGAACACACTGTTGCAGAGAGCCCCCCA GTGTCTTGGGAAATTTATTGAGATTGCTGCCCGAAAGAAGCGAAATTTTATTCTGGATCAGACAAATGTGTCTGCTGCTGCCCAGAGGAGAAAAATGTGC CTGTTTGCAGGCTTCCAGCGAAAAGCTGTTGTAGTTTGCCCAAAAGATGAAGACTATAAGCAAAGAACACAGAAGAAAGCAGAAGTAGAGGGGAAAGACC TACCAGAACATGCGGTCCTCAAAATGAAAGGAAACTTTACCCTCCCAGAGGTAGCTGAGTGCTTTGATGAAATAACCTATGTTGAACTTCAGAAGGAAGA AGCCCAAAAACTCTTGGAGCAATATAAGGAAGAAAGCAAAAAGGCTCTTCCACCAGAAAAGAAACAGAACACTGGCTCAAAGAAAAGCAATAAAAATAAG AGTGGCAAGAACCAGTTTAACAGAGGTGGTGGCCATAGAGGACGTGGAGGATTCAATATGCGTGGTGGAAATTTCAGAGGAGGAGCCCCTGGGAATCGTG GCGGATATAATAGGAGGGGCAACATGCCACAGAGAGGTGGTGGCGGTGGAGGAAGTGGTGGAATCGGCTATCCATACCCTCGTGCCCCTGTTTTTCCTGG CCGTGGTAGTTACTCAAACAGAGGGAACTACAACAGAGGTGGAATGCCCAACAGAGGGAACTACAACCAGAACTTCAGAGGACGAGGAAACAATCGTGGC TACAAAAATCAATCTCAGGGCTACAACCAGTGGCAGCAGGGTCAATTCTGGGGTCAGAAGCCATGGAGTCAGCATTATCACCAAGGATATTATTGAATAC CCAAATAAAACGAACTGATACATATTTCTCCAAAACCTTCACAAGAAGTCGACTGTTTTCTTTAGTAGGCTAACTTTTTAAACATTCCACAAGAGGAAGT GCCTGCGGGTTCCTTTTTTAGAAGCTTTGTGGGTTGATTTTTTTTCTTTTCTTTTTTGTACATTTTTAATTGCAGTTTAAAAGTGAATCGTAAGAGAACC TCAGCATTGTGCACGATAAGAGAATGTGTCAGTATTTCAGGGTTCTACATTTTATCTGTAAAATGTGACTTTTTTTTTTTTTTATCACAACAGAAGTAAA ATGTTGCTTTGTACCTGGTGTCTTTTATTAAGAATTTACTCCCCCCATTTCTCACAGAGAATAACAGTCGGGAGTCATTGTCACAATATAATAGAAATGT TAGCAACCAGATTCATGTAAGGACTAAGTGGTCCTCATGAATTGCATTAAGACTCTGTACTGCTCATATTACACTCCATCCTCTCTGTAGTTTGCTGGGT AGTGGAGGGGGTAAGCTAAATCATAGTTTCTGACAATAACTGGGAAGGTTTTTTCTTAAAATAACAATGGAATTGGTATAATTGGGATTGAAAACTAAAA CTTGGAACTAAGATAGAGAAGATGGAGTGTATGTAGAAGGGCTGTTAAAAATGTAAAACTTGGTTGCATTATTTGTGGAGGCTCAAACTTGTGAAGGTTA ATACCATAATTTTTCCATTTGTTCTGCATTTTGATTCTGAAAAGAAAGCTGGCTTTGCCCATTTCTTATTAAAAAAACTTGTTGTAAATCCAGTTGTCTA ATGGGATCTATATGAAGTTAGCCATGTCTGTATGCCCTTCTCCCACAAAATACTGTATAACTAGTGTGCTTGTAGTAGTTAACTCCACCATCTTTGTAAG CTAATGAAATTGTGAGTCACCCATTTATATCTTAATTTTTAATCATGTCAGTTCTTGAATGGGTATCTCCTTAGCCTGCTGATTTCTTTTTCTTTCTAAA GAAAGTGGGTGGAGAAATTAATTTAGACGTTTGTTTGCAATAAAAAGAATTCATTTTACTCTTGTTTTGGGATTCTCGCCATCAAGGTTCAAAATCCCTT TATATAACTCCCAAGAGGAGAAATTTATTAAGTGTGTGCTTTCTGGACAGCTTATTCTTTACTCTGCATAGAACATTTAGGTTTTAAAAACTTAAATGTA TACTGACAATTGATACATAATTATGAAGTAAAGTTGAATTCTTCCCTTCCCCTCCCCCCCAGACAACTTTTAACATATTTAATGAGGGGAAAAGGTACTG GCTGGGAGAAGTTAACACTGAGTTTATCATCTTTACAGAATGCTAATGCTGTCCTCAACTGATTATTTTATATACATATATATGATACATGAAACTCTGG GATCAGATGCTTTTAGAAGCCATCATGCAAGCCAGTCATTGATGTCACTGCTACACAACACTGCTAACTTGACTGTAGCTATGTAATAACATTAGATCCC CTAATTGTAATTATATTGGGTTTGCACAGAACACTTTAATCTTCCCCTCACCAATGTGAAGTGAGGAATCAGGAGTCAAACTGTAGAACTAAAATTTGAC TTCAGTCTAGCGTTTCCTTGGTGTTTTTAGGTTGCTTTGGTAAGTTTAGGTTTGCTATATTTCTGATTGCTTAGAATTTTGTTTTAGCCCTTTAAAATCA GATCATAAATATGAATTCATACTTCTAAGGAATTTTCTTGCTATAAGCTGGAGTTTAGGTGATGTATAGGTTCAGTTGAGACATTTTTGGAACAGGCAAA TCCTTAGTTAACATAAGATATTTAACAGTTGAAGATAGTGTCATGGATTTTTATCTTTTTTAGCAAGTAATGCTAAGAACCACTGGCCTGAGCTACTACT CTTCAGTATACATTATTAGGATTGCATAGACTTACTAGAGGAACAGTTTCAGGTTTTGATGCTAATCAGTGTTGTGTCCTAAAGTTGTCCTTTGTGCCTT TAAAAAGTTTTGGATATATCTTCTAGTTTAAAATTGCTTATTAAGGAATTCATTTTATAATTGCAGTGGGAAAGTAATGGTCAAGTAACACTAGGTAGAC TATCATGCCTGTTTAGCCCAGAGAATTTGGGGGGAGAGAGAATAGATAAAAATGGCACCCAGAAAAATGTTAAAATCTTTAGTCAAGACTAGAATTAATA CAATTGTCTACACTTGTATGGCAGAAATAACCTTATAAAGTGTTTAAGGAATTCAGAGAAGGGAATGTACCAAATAAGCAACAGGGAGAAAATTAGGTAA GAAGTAAGATACGAACGAGAAACCTGATTTATTGCTCATCCTTCCCTTGCCTCCCTAATGGCAAGCAAAACTCTGAACATCTGAAAAGGATGTAGTTCTG GACAAATCCTGACTACCCAGAGGAAACTCACTGTGAGATTGCTGTTGATTTGAAGGGTGCTTTCACTAAGGTTATATTTTAAAGTAGAATAACACATGCT GAGTGTAAACTGGCTTTGGATTGGTCAGCTGCAGTAGTACAAAAACAGCATAGAATTTGAGAAAACTAAAACTGCTATGAGATAGCTATGAGAAAACTAA AACTGCTATGAGATAGAAATGATGTAAAATTATGTGGAAAGTTTTCCCTCATATACTCACATACAGCCTTTGAAGGGCTCTGGCTCTGACCGGTTGATGG CCTTGAGCGAGATGAAATCATGAAATTGAGTCAAATCAATTTGACATTGAAATGACAAGAGGAAACTCTTAAATACATAAAAACAAGCTCTCATTTGCCT AGGATAGATACTGTCTTAAAAATAAAGACTGAACCTAGATGTTCTGAGCACTAGCAACAAGGTATTTTAACAAGTTTAAAGGAATTCTCTGAAAAAGTTA TAAAATTATTCTAGGAAACATAACCATAATAGTGTTTTAAGGGACTTTCACCTGGGGATTTTATATTCATGAACAGAGTGTATTCTGTATTTAAAATGTC TCATTTGTGGGAATTGGATGACATGTTTTTTGATAAATTTATTCACAATATAAATTGACTTTTTATTCTAGGACCATGTGAATAATGGGTTCCATTGCAC AAATACAAATATTTTAATAGCTTCTTAGGCAGTGGTGTAGACATCTTGGATATAAATAATTGTAGATCTTGTATATTTGATTTTTAAAAAACTAGAATAA ACAGAGAGGCATAAACATATCTTAGAGTCCAAGTGGTAGTGTTTAGCATTGGATATAATAAATGGATGTTTTACAAAGTGTTTCCATAATTCTCTTCCTA TACATAAATGTCTTGTTTTCAAAAGTGGATGGAACTTGGCTGGGTGTGGTGGCTCACGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGCGGGAGGATCA CTTGAGCTCAGGAGTTTGAGACCATCCTGGGCAACATAGTGAGACCTGGTCTCTTGAAAAAAAAAAAGTGGATGGAACTTGTAGCAGAGAATTTTATCTA CTTCTCAACCTGCTTCAGAATACCCATTTGAGATGTTCCCCTGGAAAGATGAACACAATACTGCATCTGAAGCCATTTCTTCCCACCTAACATTCTTAAA ATGATTAGAGTCTAAACTTTGTCATTCATTCCTAATTCTGGAGCTCTGAGGTTGAGGTGTTCAGAGTTTGGTGAATAATTGGGTTTAAGTTTTAACATTT TAGTAATAATAAAAGCAAACACATACATGTTAAGGCCTGACAATAGGTTGCAATACCCATGCATTGGGACTCATACCCAGCATAAATGGTGAGGGACTGA ACATTAGTGCTTTGAGCAAGAATTGGTTAACTACCTGAGATCTCTAAAACAGTAATTTGAATTACTAATACATAAACCACAAGTCTCTTCGAATTGTTAA TTGCCTAAATTTACCCTAAAACTTAGTTAACGCTGCAGTGCCTTTATTAAAGCTTTTTTTTGGGGGGGGGTGTGGGCACAGCTACTCCATAACTTTAAAT TTTAAAGCATGAAGGTGATCTAGCTAGTGTTAGTGCTTGAGTTGGTAGTTACATAGGCTGCTCTTGAATCGTCCTGTTTTCTTTGCCTAGTATTAGCACC ACAGGTACATATTTGTAAAATAAGCATTAAAAGTACTTTGTCCAGC

refseq_HNRPU.F2 (forward primer)
refseq_HNRPU.R2 (reverse primer)
Alternative donor

Frame 0

LAPGESPRLPRELGERNWRRSTPGGSALQHEPI SSRSRSRRPGRGAAAAAATSGRVSGAEFEAAPSG ESGPSP*VPRLLM*KS*RCRS*KRSSRSDAFLT RVSRPSSWSDSRLRWTTRRPGAAPPWSPGTAA* TWAGIPLGAREQASSRRPRPAAMKRRRKRKRRRK ESPLWTATRWS*ERRTGPRGRPTRARWRRRRPP RKTRTATIRVSRKGKMSSGTKRKARATRTGTGS SSLNRRRRSSNSPNSSAGPPRRPRGRAAAPPRCS R*RWRRPGRGRASSRREVRRRRKAAEAAVAPGL RRRGTAKQNRKAEIKRGVLKDHEKIMAVDILST LKRTSIAEPNLLSHLLKKKMNTSMTQWFVLILII VIYILKYQEIVSVLLPLQWRVLLFFGLEEEHPM VCQKAKCVLR*RLQRRSQ*GIYIQKILTYMKFV LAGH*LQVECYLVKKNFLMGIL*KE*KHATVRLK IMEKSLMKMM*LHVLLTLKVMK*NSRMLRMDKI LALPSKSVRKFLLDGHCSRMFSATTVQLNLILV RRKSHIFQYLKSILSSRTSP*RIELEDQRGLKRR KIVKL***LACQELEKLPGLLNMQQKIQGNITF LAQILLWIR*WWQVLRSKWQILEN*THCCREPP SVLGNLLRLLPERSEILFWIRQMCLLLPRGEKCA CLQASSEKLL*FAQKMKTISKEHRRKQK*RGKT YQNMRSSK*KETLPSQR*LSALMK*PMLNFRRK KPKNSWSNIRKKAKRLFHQKRNRTLAQRKAIKIR VARTSLTEVVAIEDVEDSICVVEISEEEPLGIV ADIIGGATCHREVVAVEEVVESAIHTLVPLFFL AVVVTQTEGTTTEVECPTEGTTTRTSEDEETIVA TKINLRATTSGSRVNSGVRSHGVSIITKDIIEY PNKTN*YIFLQNLHKKSTVFFSRLTF*TFHKRK CLRVPFLEALWVDFFSFLFCTFLIAV*K*IVREP QHCAR*ENVSVFQGSTFYL*NVTFFFFYHNRSK MLLCTWCLLLRIYSPHFSQRITVGSHCHNIIEM LATRFM*GLSGPHELH*DSVLLILHSILSVVCWV VEGVS*IIVSDNNWEGFFLK*QWNWYNWD*KLK LGTKIEKMECM*KGC*KCKTWLHYLWRLKLVKV NTIIFPFVLHFDSEKKAGFAHFLLKKLVVNPVV* WDLYEVSHVCMPFSHKILYN*CACSS*LHHLCK LMKL*VTHLYLNF*SCQFLNGYLLSLLISFSF* RKWVEKLI*TFVCNKKNSFYSCFGILAIKVQNPF I*LPRGEIY*VCAFWTAYSLLCIEHLGFKNLNV Y*QLIHNYEVKLNSSLPLPPRQLLTYLMRGKGT GWEKLTLSLSSLQNANAVLN*LFYIHIYDT*NSG IRCF*KPSCKPVIDVTATQHC*LDCSYVITLDP LIVIILGLHRTL*SSPHQCEVRNQESNCRTKI* LQSSVSLVFLGCFGKFRFAIFLIA*NFVLAL*NQ IINMNSYF*GIFLL*AGV*VMYRFS*DIFGTGK SLVNIRYLTVEDSVMDFYLF*QVMLRTTGLSYY SSVYIIRIA*TY*RNSFRF*C*SVLCPKVVLCAF KKFWIYLLV*NCLLRNSFYNCSGKVMVK*H*VD YHACLAQRIWGERE*IKMAPRKMLKSLVKTRIN TIVYTCMAEITL*SV*GIQRRECTK*ATGRKLGK K*DTNEKPDLLLILPLPP*WQAKL*TSEKDVVL DKS*LPRGNSL*DCC*FEGCFH*GYILK*NNTC *V*TGFGLVSCSSTKTA*NLRKLKLL*DSYEKTK TAMR*K*CKIMWKVFPHILTYSL*RALALTG*W P*AR*NHEIESNQFDIEMTRGNS*IHKNKLSFA *DRYCLKNKD*T*MF*ALATRYFNKFKGIL*KSY KIILGNITIIVF*GTFTWGFYIHEQSVFCI*NV SFVGIG*HVF**IYSQYKLTFYSRTM*IMGSIA QIQIF**LLRQWCRHLGYK*L*ILYI*FLKN*NK QRGINIS*SPSGSV*HWI**MDVLQSVSIILFL YINVLFSKVDGTWLGVVAHACNPSTLGGQGGRI T*AQEFETILGNIVRPGLLKKKKWMELVAENFIY FSTCFRIPI*DVPLER*TQYCI*SHFFPPNILK MIRV*TLSFIPNSGALRLRCSEFGE*LGLSFNI LVIIKANTYMLRPDNRLQYPCIGTHTQHKW*GTE H*CFEQELVNYLRSLKQ*FELLIHKPQVSSNC* LPKFTLKLS*RCSAFIKAFFWGGVWAQLLHNFK F*SMKVI*LVLVLELVVT*AALESSCFLCLVLAP QVHICKISIKSTLSS

Frame 1

SRQASLRVSLANSVKGIGAVRHQADPLCSTNPS PAAAAAAARAEEQPQQPPPVAE*AEPSLRQRLA VNRGPHHEFLAC*CKKAEGVGAERGAQEATPF*Q GSQGRAHGATPGCAGRRGGRGPPRHGARERQPR PGRGFRWALGSRPRAGGRGRRR*RGGGRGRGGG RNLRSGRRPDGARRGERGRGGGRLGPDGGGGGRL GRRERRRSGFPGRGR*ARGRRGRRGRRERARGA AASTAGDAAATAPTAARGRQGGRGEEQRPHLAV RGDGGAARGEAGPAAGGR*EEGGRRRRRRSPRGS GGGGRQNRTERRR*KEGC*KTTRRSWPWIF*VH *REQV*QSQISSATC*RRR*TLR*HSGLS*YL* L*STF*NIKRSSQCFFPYNGEFCFSLGWRKSILW CVKRQSVF*DEGYREDPSKAFIYKRY*HT*SSY WLVTNYKWNVTW*RRIFLWVFSKRNKNMQL*D* RLWRKV**K*CDYMFC*L*K**SRTLVC*EWTRS WRCLQNQ*GSSCWTATVPACSLPQLCS*I*FWS EGKAIFSNT*RVYFHPERPLRGSS*RTKGA*RE ERL*SCDDDWLARSWKNYLGY*TCSRKSREI*HS WHKYYYG*DDGGRF*EANGRYWKTEHTVAESPP VSWEIY*DCCPKEAKFYSGSDKCVCCCPEEKNV PVCRLPAKSCCSLPKR*RL*AKNTEESRSRGERP TRTCGPQNERKLYPPRGS*VL**NNLC*TSEGR SPKTLGAI*GRKQKGSSTRKETEHWLKEKQ*K* EWQEPV*QRWWP*RTWRIQYAWWKFQRRSPWESW RI**EGQHATERWWRWRKWWNRLSIPSCPCFSW PW*LLKQRELQQRWNAQQRELQPELQRTRKQSW LQKSISGLQPVAAGSILGSEAMESALSPRILLNT QIKRTDTYFSKTFTRSRLFSLVG*LFKHSTRGS ACGFLF*KLCGLIFFLFFFVHF*LQFKSES*EN LSIVHDKRMCQYFRVLHFICKM*LFFFFITTEVK CCFVPGVFY*EFTPPISHRE*QSGVIVTI**KC *QPDSCKD*VVLMNCIKTLYCSYYTPSSL*FAG *WRG*AKS*FLTITGKVFS*NNNGIGIIGIEN*N LELR*RRWSVCRRAVKNVKLGCIICGGSNL*RL IP*FFHLFCILILKRKLALPISY*KNLL*IQLS NGIYMKLAMSVCPSPTKYCITSVLVVVNSTIFVS **NCESPIYILIFNHVSS*MGISLAC*FLFLSK ESGWRN*FRRLFAIKRIHFTLVLGFSPSRFKIP LYNSQEEKFIKCVLSGQLILYSA*NI*VLKT*MY TDN*YIIMK*S*ILPFPSPPDNF*HI**GEKVL AGRS*H*VYHLYRMLMLSSTDYFIYIYMIHETL GSDAFRSHHASQSLMSLLHNTANLTVAM**H*IP *L*LYWVCTEHFNLPLTNVK*GIRSQTVELKFD FSLAFPWCF*VALVSLGLLYF*LLRILF*PFKI RS*I*IHTSKEFSCYKLEFR*CIGSVETFLEQAN P*LT*DI*QLKIVSWIFIFFSK*C*EPLA*ATT LQYTLLGLHRLTRGTVSGFDANQCCVLKLSFVP LKSFGYIF*FKIAY*GIHFIIAVGK*WSSNTR*T IMPV*PREFGGRENR*KWHPEKC*NL*SRLELI QLSTLVWQK*PYKVFKEFREGNVPNKQQGEN*V RSKIRTRNLIYCSSFPCLPNGKQNSEHLKRM*FW TNPDYPEETHCEIAVDLKGAFTKVIF*SRITHA ECKLALDWSAAVVQKQHRI*EN*NCYEIAMRKL KLL*DRNDVKLCGKFSLIYSHTAFEGLWL*PVDG LERDEIMKLSQINLTLK*QEETLKYIKTSSHLP RIDTVLKIKTEPRCSEH*QQGILTSLKEFSEKV IKLF*ET*P**CFKGLSPGDFIFMNRVYSVFKMS HLWELDDMFFDKFIHNIN*LFILGPCE*WVPLH KYKYFNSFLGSGVDILDINNCRSCIFDF*KTRI NREA*TYLRVQVVVFSIGYNKWMFYKVFP*FSSY T*MSCFQKWMELGWVWWLTPVILALWEAKAGGS LELRSLRPSWAT**DLVS*KKKSGWNL*QRILS TSQPASEYPFEMFPWKDEHNTASEAISSHLTFLK *LESKLCHSFLILEL*G*GVQSLVNNWV*VLTF ****KQTHTC*GLTIGCNTHALGLIPSINGEGL NISALSKNWLTT*DL*NSNLNY*YINHKSLRIVN CLNLP*NLVNAAVPLLKLFFGGGCGHSYSITLN FKA*R*SS*C*CLSW*LHRLLLNRPVFFA*Y*H HRYIFVK*ALKVLCP

Frame 2

RARRVSASPSRTR*KELAPFDTRRIRSAARTHL QPQPQPPPGPRSSRSSRHQWPSERSRV*GSA*R *IGALTMSSSPVNVKKLKVSELKEELKKRRLSD KGLKAELMERLQAALDDEEAGGRPAMEPGNGSLD LGGDSAGRSGAGLEQEAAAGGDEEEEEEEEEEE GISALDGDQMELGEENGAAGAADSGPMEEEEAA SEDENGDDQGFQEGEDELGDEEEGAGDENGHGEQ QPQPPATQQQQPQQQRGAAKEAAGKSSGPTSLF AVTVAPPGARQGQQQAGGKKKAEGGGGGGRPGA PAAGDGKTEQKGGDKKRGVKRPREDHGRGYFEYI EENKYSRAKSPQPPVEEEDEHFDDTVVCLDTYN CDLHFKISRDRLSASSLTMESFAFLWAGGRASY GVSKGKVCFEMKVTEKIPVRHLYTKDIDIHEVRI GWSLTTSGMLLGEEEFSYGYSLKGIKTCNCETE DYGEKFDENDVITCFANFESDEVELSYAKNGQD LGVAFKISKEVLAGRPLFPHVLCHNCAVEFNFGQ KEKPYFPIPEEYTFIQNVPLEDRVRGPKGPEEK KDCEVVMMIGLPGAGKTTWVTKHAAENPGKYNI LGTNTIMDKMMVAGFKKQMADTGKLNTLLQRAPQ CLGKFIEIAARKKRNFILDQTNVSAAAQRRKMC LFAGFQRKAVVVCPKDEDYKQRTQKKAEVEGKD LPEHAVLKMKGNFTLPEVAECFDEITYVELQKEE AQKLLEQYKEESKKALPPEKKQNTGSKKSNKNK SGKNQFNRGGGHRGRGGFNMRGGNFRGGAPGNR GGYNRRGNMPQRGGGGGGSGGIGYPYPRAPVFPG RGSYSNRGNYNRGGMPNRGNYNQNFRGRGNNRG YKNQSQGYNQWQQGQFWGQKPWSQHYHQGYY*I PK*NELIHISPKPSQEVDCFL**ANFLNIPQEEV PAGSFFRSFVG*FFFFSFLYIFNCSLKVNRKRT SALCTIRECVSISGFYILSVKCDFFFFLSQQK* NVALYLVSFIKNLLPPFLTENNSRESLSQYNRNV SNQIHVRTKWSS*IALRLCTAHITLHPLCSLLG SGGGKLNHSF*Q*LGRFFLKITMELV*LGLKTK TWN*DREDGVYVEGLLKM*NLVALFVEAQTCEG* YHNFSICSAF*F*KESWLCPFLIKKTCCKSSCL MGSI*S*PCLYALLPQNTV*LVCL**LTPPSL* ANEIVSHPFIS*FLIMSVLEWVSP*PADFFFFLK KVGGEINLDVCLQ*KEFILLLFWDSRHQGSKSL YITPKRRNLLSVCFLDSLFFTLHRTFRF*KLKC ILTIDT*L*SKVEFFPSPPPQTTFNIFNEGKRYW LGEVNTEFIIFTEC*CCPQLIILYTYI*YMKLW DQMLLEAIMQASH*CHCYTTLLT*L*LCNNIRS PNCNYIGFAQNTLIFPSPM*SEESGVKL*N*NLT SV*RFLGVFRLLW*V*VCYISDCLEFCFSPLKS DHKYEFILLRNFLAISWSLGDV*VQLRHFWNRQ ILS*HKIFNS*R*CHGFLSFLASNAKNHWPELLL FSIHY*DCIDLLEEQFQVLMLISVVS*SCPLCL *KVLDISSSLKLLIKEFIL*LQWESNGQVTLGR LSCLFSPENLGGERIDKNGTQKNVKIFSQD*N*Y NCLHLYGRNNLIKCLRNSEKGMYQISNREKIR* EVRYERET*FIAHPSLASLMASKTLNI*KGCSS GQILTTQRKLTVRLLLI*RVLSLRLYFKVE*HML SVNWLWIGQLQ*YKNSIEFEKTKTAMR*L*EN* NCYEIEMM*NYVESFPSYTHIQPLKGSGSDRLM ALSEMKS*N*VKSI*H*NDKRKLLNT*KQALICL G*ILS*K*RLNLDVLSTSNKVF*QV*RNSLKKL *NYSRKHNHNSVLRDFHLGILYS*TECILYLKC LICGNWMTCFLINLFTI*IDFLF*DHVNNGFHCT NTNILIAS*AVV*TSWI*IIVDLVYLIFKKLE* TERHKHILESKW*CLALDIINGCFTKCFHNSLP IHKCLVFKSGWNLAGCGGSRL*S*HFGRPRREDH LSSGV*DHPGQHSETWSLEKKKVDGTCSREFYL LLNLLQNTHLRCSPGKMNTILHLKPFLPT*HS* ND*SLNFVIHS*FWSSEVEVFRVW*IIGFKF*HF SNNKSKHIHVKA*Q*VAIPMHWDSYPA*MVRD* TLVL*ARIG*LPEISKTVI*ITNT*TTSLFELL IA*IYPKT*LTLQCLY*SFFLGGGVGTATP*L*I LKHEGDLASVSA*VGSYIGCS*IVLFSLPSIST TGTYL*NKH*KYFVQ