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Sequences

Sequence NM_003582

ACTTCCCAGCCGGGGCCAGTCGGGAGCGAAAGTGCGCTGAGCTGCAGTGTCTGGTCGAGAGTACCCGTGGGAGCGTCGCGCCGCGGAGGCAGCCGTCCCG
GCGTAGGTGGCGTGGCCGACCGGACCCCCAACTGGCGCCTCTCCCCGCGCGGGGTCCCGAGCTAGGAGATGGGAGGCACAGCTCGTGGGCCTGGGCGGAA
GGATGCGGGGCCGCCTGGGGCCGGGCTCCCGCCCCAGCAGCGGAGGTTGGGGGATGGTGTCTATGACACCTTCATGATGATAGATGAAACCAAATGTCCC
CCCTGTTCAAATGTACTCTGCAATCCTTCTGAACCACCTCCACCCAGAAGACTAAATATGACCACTGAGCAGTTTACAGGAGATCATACTCAGCACTTTT
TGGATGGAGGTGAGATGAAGGTAGAACAGCTGTTTCAAGAATTTGGCAACAGAAAATCCAATACTATTCAGTCAGATGGCATCAGTGACTCTGAAAAATG
CTCTCCTACTGTTTCTCAGGGTAAAAGTTCAGATTGCTTGAATACAGTAAAATCCAACAGTTCATCCAAGGCACCCAAAGTGGTGCCTCTGACTCCAGAA
CAAGCCCTGAAGCAATATAAACACCACCTCACTGCCTATGAGAAACTGGAAATAATTAATTATCCAGAAATTTACTTTGTAGGTCCAAATGCCAAGAAAA
GACATGGAGTTATTGGTGGTCCCAATAATGGAGGGTATGATGATGCAGATGGGGCCTATATTCATGTACCTCGAGACCATCTAGCTTATCGATATGAGGT
GCTGAAAATTATTGGCAAGGGGAGTTTTGGGCAGGTGGCCAGGGTCTATGATCACAAACTTCGACAGTACGTGGCCCTAAAAATGGTGCGCAATGAGAAG
CGCTTTCATCGTCAAGCAGCTGAGGAGATCCGGATTTTGGAGCATCTTAAGAAACAGGATAAAACTGGTAGTATGAACGTTATCCACATGCTGGAAAGTT
TCACATTCCGGAACCATGTTTGCATGGCCTTTGAATTGCTGAGCATAGACCTTTATGAGCTGATTAAAAAAAATAAGTTTCAGGGTTTTAGCGTCCAGTT
GGTACGCAAGTTTGCCCAGTCCATCTTGCAATCTTTGGATGCCCTCCACAAAAATAAGATTATTCACTGCGATCTGAAGCCAGAAAACATTCTCCTGAAA
CACCACGGGCGCAGTTCAACCAAGGTCATTGACTTTGGGTCCAGCTGTTTCGAGTACCAGAAGCTCTACACATATATCCAGTCTCGGTTCTACAGAGCTC
CAGAAATCATCTTAGGAAGCCGCTACAGCACACCAATTGACATATGGAGTTTTGGCTGCATCCTTGCAGAACTTTTAACAGGACAGCCTCTCTTCCCTGG
AGAGGATGAAGGAGACCAGTTGGCCTGCATGATGGAGCTTCTAGGGATGCCACCACCAAAACTTCTGGAGCAATCCAAACGTGCCAAGTACTTTATTAAT
TCCAAGGGCATACCCCGCTACTGCTCTGTGACTACCCAGGCAGATGGGAGGGTTGTGCTTGTGGGGGGTCGCTCACGTAGGGGTAAAAAGCGGGGTCCCC
CAGGCAGCAAAGACTGGGGGACAGCACTGAAAGGGTGTGATGACTACTTGTTTATAGAGTTCTTGAAAAGGTGTCTTCACTGGGACCCCTCTGCCCGCTT
GACCCCAGCTCAAGCATTAAGACACCCTTGGATTAGCAAGTCTGTCCCCAGACCTCTCACCACCATAGACAAGGTGTCAGGGAAACGGGTAGTTAATCCT
GCAAGTGCTTTCCAGGGATTGGGTTCTAAGCTGCCTCCAGTTGTTGGAATAGCCAATAAGCTTAAAGCTAACTTAATGTCAGAAACCAATGGTAGTATAC
CCCTATGCAGTGTATTGCCAAAACTGATTAGCTAGTGGACAGAGATATGCCCAGAGATGCATATGTGTATATTTTTATGATCTTACAAACCTGCAAATGG
AAAAAATGCAAGCCCATTGGTGGATGTTTTTGTTAGAGTAGACTTTTTTTAAACAAGACAAAACATTTTTATATGATTATAAAAGAATTCTTCAAGGGCT
AATTACCTAACCAGCTTGTATTGGCCATCTGGAATATGCATTAAATGACTTTTTATAGGTCAATGCA
  • refseq_DYRK3.F1 (forward primer)
  • refseq_DYRK3.R1 (reverse primer)
  • Single exon skipping

Frame 0

TSQPGPVGSESALSCSVWSRVPVGASRRGGSRP
GVGGVADRTPNWRLSPRGVPS*EMGGTARGPGRK
DAGPPGAGLPPQQRRLGDGVYDTFMMIDETKCP
PCSNVLCNPSEPPPPRRLNMTTEQFTGDHTQHF
LDGGEMKVEQLFQEFGNRKSNTIQSDGISDSEKC
SPTVSQGKSSDCLNTVKSNSSSKAPKVVPLTPE
QALKQYKHHLTAYEKLEIINYPEIYFVGPNAKK
RHGVIGGPNNGGYDDADGAYIHVPRDHLAYRYEV
LKIIGKGSFGQVARVYDHKLRQYVALKMVRNEK
RFHRQAAEEIRILEHLKKQDKTGSMNVIHMLES
FTFRNHVCMAFELLSIDLYELIKKNKFQGFSVQL
VRKFAQSILQSLDALHKNKIIHCDLKPENILLK
HHGRSSTKVIDFGSSCFEYQKLYTYIQSRFYRA
PEIILGSRYSTPIDIWSFGCILAELLTGQPLFPG
EDEGDQLACMMELLGMPPPKLLEQSKRAKYFIN
SKGIPRYCSVTTQADGRVVLVGGRSRRGKKRGP
PGSKDWGTALKGCDDYLFIEFLKRCLHWDPSARL
TPAQALRHPWISKSVPRPLTTIDKVSGKRVVNP
ASAFQGLGSKLPPVVGIANKLKANLMSETNGSI
PLCSVLPKLIS*WTEICPEMHMCIFL*SYKPANG
KNASPLVDVFVRVDFF*TRQNIFI*L*KNSSRA
NYLTSLYWPSGICIK*LFIGQC

Frame 1

LPSRGQSGAKVR*AAVSGREYPWERRAAEAAVP
A*VAWPTGPPTGASPRAGSRARRWEAQLVGLGG
RMRGRLGPGSRPSSGGWGMVSMTPS***MKPNVP
PVQMYSAILLNHLHPED*I*PLSSLQEIILSTF
WMEVR*R*NSCFKNLATENPILFSQMASVTLKN
ALLLFLRVKVQIA*IQ*NPTVHPRHPKWCL*LQN
KP*SNINTTSLPMRNWK*LIIQKFTL*VQMPRK
DMELLVVPIMEGMMMQMGPIFMYLETI*LIDMR
C*KLLARGVLGRWPGSMITNFDSTWP*KWCAMRS
AFIVKQLRRSGFWSILRNRIKLVV*TLSTCWKV
SHSGTMFAWPLNC*A*TFMS*LKKISFRVLASS
WYASLPSPSCNLWMPSTKIRLFTAI*SQKTFS*N
TTGAVQPRSLTLGPAVSSTRSSTHISSLGSTEL
QKSS*EAATAHQLTYGVLAASLQNF*QDSLSSL
ERMKETSWPA*WSF*GCHHQNFWSNPNVPSTLLI
PRAYPATAL*LPRQMGGLCLWGVAHVGVKSGVP
QAAKTGGQH*KGVMTTCL*SS*KGVFTGTPLPA
*PQLKH*DTLGLASLSPDLSPP*TRCQGNG*LIL
QVLSRDWVLSCLQLLE*PISLKLT*CQKPMVVY
PYAVYCQN*LASGQRYAQRCICVYFYDLTNLQM
EKMQAHWWMFLLE*TFFKQDKTFLYDYKRILQGL
IT*PACIGHLEYALNDFL*VNA

Frame 2

FPAGASRERKCAELQCLVESTRGSVAPRRQPSR
RRWRGRPDPQLAPLPARGPELGDGRHSSWAWAE
GCGAAWGRAPAPAAEVGGWCL*HLHDDR*NQMS
PLFKCTLQSF*TTSTQKTKYDH*AVYRRSYSALF
GWR*DEGRTAVSRIWQQKIQYYSVRWHQ*L*KM
LSYCFSG*KFRLLEYSKIQQFIQGTQSGASDSR
TSPEAI*TPPHCL*ETGNN*LSRNLLCRSKCQEK
TWSYWWSQ*WRV**CRWGLYSCTSRPSSLSI*G
AENYWQGEFWAGGQGL*SQTSTVRGPKNGAQ*E
ALSSSSS*GDPDFGAS*ETG*NW*YERYPHAGKF
HIPEPCLHGL*IAEHRPL*AD*KK*VSGF*RPV
GTQVCPVHLAIFGCPPQK*DYSLRSEARKHSPE
TPRAQFNQGH*LWVQLFRVPEALHIYPVSVLQSS
RNHLRKPLQHTN*HMEFWLHPCRTFNRTASLPW
RG*RRPVGLHDGASRDATTKTSGAIQTCQVLY*
FQGHTPLLLCDYPGRWEGCACGGSLT*G*KAGSP
RQQRLGDSTERV**LLVYRVLEKVSSLGPLCPL
DPSSSIKTPLD*QVCPQTSHHHRQGVRETGS*S
CKCFPGIGF*AASSCWNSQ*A*S*LNVRNQW*YT
PMQCIAKTD*LVDRDMPRDAYVYIFMILQTCKW
KKCKPIGGCFC*SRLFLNKTKHFYMIIKEFFKG
*LPNQLVLAIWNMH*MTFYRSM

Sequence NM_001004023

ACTTCCCAGCCGGGGCCAGTCGGGAGCGAAAGTGCGCTGAGCTGCAGTGTCTGGTCGAGAGTACCCGTGGGAGCGTCGCGCCGCGGAGGCAGCCGTCCCG
GCGTAGGTGGCGTGGCCGACCGGACCCCCAACTGGCGCCTCTCCCCGCGCGGGGTCCCGAGCTAGGAGATGGGAGGCACAGCTCGTGGGCCTGGGCGGAA
GGATGCGGGGCCGCCTGGGGCCGGGCTCCCGCCCCAGCAGCGGAGTGGTGGAGCCACAGTGTTAAAGAACAGAGAAGTGATCCTTAATCATTTAGAATTT
TGCCTCCACCATCCACCAGAAAATGAAGTGGAAAGAGAAGTTGGGGGATGGTGTCTATGACACCTTCATGATGATAGATGAAACCAAATGTCCCCCCTGT
TCAAATGTACTCTGCAATCCTTCTGAACCACCTCCACCCAGAAGACTAAATATGACCACTGAGCAGTTTACAGGAGATCATACTCAGCACTTTTTGGATG
GAGGTGAGATGAAGGTAGAACAGCTGTTTCAAGAATTTGGCAACAGAAAATCCAATACTATTCAGTCAGATGGCATCAGTGACTCTGAAAAATGCTCTCC
TACTGTTTCTCAGGGTAAAAGTTCAGATTGCTTGAATACAGTAAAATCCAACAGTTCATCCAAGGCACCCAAAGTGGTGCCTCTGACTCCAGAACAAGCC
CTGAAGCAATATAAACACCACCTCACTGCCTATGAGAAACTGGAAATAATTAATTATCCAGAAATTTACTTTGTAGGTCCAAATGCCAAGAAAAGACATG
GAGTTATTGGTGGTCCCAATAATGGAGGGTATGATGATGCAGATGGGGCCTATATTCATGTACCTCGAGACCATCTAGCTTATCGATATGAGGTGCTGAA
AATTATTGGCAAGGGGAGTTTTGGGCAGGTGGCCAGGGTCTATGATCACAAACTTCGACAGTACGTGGCCCTAAAAATGGTGCGCAATGAGAAGCGCTTT
CATCGTCAAGCAGCTGAGGAGATCCGGATTTTGGAGCATCTTAAGAAACAGGATAAAACTGGTAGTATGAACGTTATCCACATGCTGGAAAGTTTCACAT
TCCGGAACCATGTTTGCATGGCCTTTGAATTGCTGAGCATAGACCTTTATGAGCTGATTAAAAAAAATAAGTTTCAGGGTTTTAGCGTCCAGTTGGTACG
CAAGTTTGCCCAGTCCATCTTGCAATCTTTGGATGCCCTCCACAAAAATAAGATTATTCACTGCGATCTGAAGCCAGAAAACATTCTCCTGAAACACCAC
GGGCGCAGTTCAACCAAGGTCATTGACTTTGGGTCCAGCTGTTTCGAGTACCAGAAGCTCTACACATATATCCAGTCTCGGTTCTACAGAGCTCCAGAAA
TCATCTTAGGAAGCCGCTACAGCACACCAATTGACATATGGAGTTTTGGCTGCATCCTTGCAGAACTTTTAACAGGACAGCCTCTCTTCCCTGGAGAGGA
TGAAGGAGACCAGTTGGCCTGCATGATGGAGCTTCTAGGGATGCCACCACCAAAACTTCTGGAGCAATCCAAACGTGCCAAGTACTTTATTAATTCCAAG
GGCATACCCCGCTACTGCTCTGTGACTACCCAGGCAGATGGGAGGGTTGTGCTTGTGGGGGGTCGCTCACGTAGGGGTAAAAAGCGGGGTCCCCCAGGCA
GCAAAGACTGGGGGACAGCACTGAAAGGGTGTGATGACTACTTGTTTATAGAGTTCTTGAAAAGGTGTCTTCACTGGGACCCCTCTGCCCGCTTGACCCC
AGCTCAAGCATTAAGACACCCTTGGATTAGCAAGTCTGTCCCCAGACCTCTCACCACCATAGACAAGGTGTCAGGGAAACGGGTAGTTAATCCTGCAAGT
GCTTTCCAGGGATTGGGTTCTAAGCTGCCTCCAGTTGTTGGAATAGCCAATAAGCTTAAAGCTAACTTAATGTCAGAAACCAATGGTAGTATACCCCTAT
GCAGTGTATTGCCAAAACTGATTAGCTAGTGGACAGAGATATGCCCAGAGATGCATATGTGTATATTTTTATGATCTTACAAACCTGCAAATGGAAAAAA
TGCAAGCCCATTGGTGGATGTTTTTGTTAGAGTAGACTTTTTTTAAACAAGACAAAACATTTTTATATGATTATAAAAGAATTCTTCAAGGGCTAATTAC
CTAACCAGCTTGTATTGGCCATCTGGAATATGCATTAAATGACTTTTTATAGGTCAATGCA
  • refseq_DYRK3.F1 (forward primer)
  • refseq_DYRK3.R1 (reverse primer)
  • Single exon skipping

Frame 0

TSQPGPVGSESALSCSVWSRVPVGASRRGGSRP
GVGGVADRTPNWRLSPRGVPS*EMGGTARGPGRK
DAGPPGAGLPPQQRSGGATVLKNREVILNHLEF
CLHHPPENEVEREVGGWCL*HLHDDR*NQMSPL
FKCTLQSF*TTSTQKTKYDH*AVYRRSYSALFGW
R*DEGRTAVSRIWQQKIQYYSVRWHQ*L*KMLS
YCFSG*KFRLLEYSKIQQFIQGTQSGASDSRTS
PEAI*TPPHCL*ETGNN*LSRNLLCRSKCQEKTW
SYWWSQ*WRV**CRWGLYSCTSRPSSLSI*GAE
NYWQGEFWAGGQGL*SQTSTVRGPKNGAQ*EAL
SSSSS*GDPDFGAS*ETG*NW*YERYPHAGKFHI
PEPCLHGL*IAEHRPL*AD*KK*VSGF*RPVGT
QVCPVHLAIFGCPPQK*DYSLRSEARKHSPETP
RAQFNQGH*LWVQLFRVPEALHIYPVSVLQSSRN
HLRKPLQHTN*HMEFWLHPCRTFNRTASLPWRG
*RRPVGLHDGASRDATTKTSGAIQTCQVLY*FQ
GHTPLLLCDYPGRWEGCACGGSLT*G*KAGSPRQ
QRLGDSTERV**LLVYRVLEKVSSLGPLCPLDP
SSSIKTPLD*QVCPQTSHHHRQGVRETGS*SCK
CFPGIGF*AASSCWNSQ*A*S*LNVRNQW*YTPM
QCIAKTD*LVDRDMPRDAYVYIFMILQTCKWKK
CKPIGGCFC*SRLFLNKTKHFYMIIKEFFKG*L
PNQLVLAIWNMH*MTFYRSM

Frame 1

LPSRGQSGAKVR*AAVSGREYPWERRAAEAAVP
A*VAWPTGPPTGASPRAGSRARRWEAQLVGLGG
RMRGRLGPGSRPSSGVVEPQC*RTEK*SLII*NF
ASTIHQKMKWKEKLGDGVYDTFMMIDETKCPPC
SNVLCNPSEPPPPRRLNMTTEQFTGDHTQHFLD
GGEMKVEQLFQEFGNRKSNTIQSDGISDSEKCSP
TVSQGKSSDCLNTVKSNSSSKAPKVVPLTPEQA
LKQYKHHLTAYEKLEIINYPEIYFVGPNAKKRH
GVIGGPNNGGYDDADGAYIHVPRDHLAYRYEVLK
IIGKGSFGQVARVYDHKLRQYVALKMVRNEKRF
HRQAAEEIRILEHLKKQDKTGSMNVIHMLESFT
FRNHVCMAFELLSIDLYELIKKNKFQGFSVQLVR
KFAQSILQSLDALHKNKIIHCDLKPENILLKHH
GRSSTKVIDFGSSCFEYQKLYTYIQSRFYRAPE
IILGSRYSTPIDIWSFGCILAELLTGQPLFPGED
EGDQLACMMELLGMPPPKLLEQSKRAKYFINSK
GIPRYCSVTTQADGRVVLVGGRSRRGKKRGPPG
SKDWGTALKGCDDYLFIEFLKRCLHWDPSARLTP
AQALRHPWISKSVPRPLTTIDKVSGKRVVNPAS
AFQGLGSKLPPVVGIANKLKANLMSETNGSIPL
CSVLPKLIS*WTEICPEMHMCIFL*SYKPANGKN
ASPLVDVFVRVDFF*TRQNIFI*L*KNSSRANY
LTSLYWPSGICIK*LFIGQC

Frame 2

FPAGASRERKCAELQCLVESTRGSVAPRRQPSR
RRWRGRPDPQLAPLPARGPELGDGRHSSWAWAE
GCGAAWGRAPAPAAEWWSHSVKEQRSDP*SFRI
LPPPSTRK*SGKRSWGMVSMTPS***MKPNVPPV
QMYSAILLNHLHPED*I*PLSSLQEIILSTFWM
EVR*R*NSCFKNLATENPILFSQMASVTLKNAL
LLFLRVKVQIA*IQ*NPTVHPRHPKWCL*LQNKP
*SNINTTSLPMRNWK*LIIQKFTL*VQMPRKDM
ELLVVPIMEGMMMQMGPIFMYLETI*LIDMRC*
KLLARGVLGRWPGSMITNFDSTWP*KWCAMRSAF
IVKQLRRSGFWSILRNRIKLVV*TLSTCWKVSH
SGTMFAWPLNC*A*TFMS*LKKISFRVLASSWY
ASLPSPSCNLWMPSTKIRLFTAI*SQKTFS*NTT
GAVQPRSLTLGPAVSSTRSSTHISSLGSTELQK
SS*EAATAHQLTYGVLAASLQNF*QDSLSSLER
MKETSWPA*WSF*GCHHQNFWSNPNVPSTLLIPR
AYPATAL*LPRQMGGLCLWGVAHVGVKSGVPQA
AKTGGQH*KGVMTTCL*SS*KGVFTGTPLPA*P
QLKH*DTLGLASLSPDLSPP*TRCQGNG*LILQV
LSRDWVLSCLQLLE*PISLKLT*CQKPMVVYPY
AVYCQN*LASGQRYAQRCICVYFYDLTNLQMEK
MQAHWWMFLLE*TFFKQDKTFLYDYKRILQGLIT
*PACIGHLEYALNDFL*VNA

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