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Sequences

Sequence NM_130437

AAAAATAACTCATATTGTCTCTGAGGTTCTTTTCCAGTGAAGTGTTTAGTATTGCTGCTATTTGGAGTACAAAGTTGGAGCTTTTAAAGAACCTGGGAGT
TCAAAAGTATAAGGAGAAATAAATGAAAAGCAGAAATATTTTGAGGCAATAAGTATAGACTCAAATCTATATTATGACCCACTTGTAGCACCACTTGGAA
TTCTACCAATAAGAGATTTATTTGGGCAAACTATAATGGTTGTTGGAAATTGCAAATCTTAGTGTGAATTATTTTAGTCCAGTTGGTTTCTTTCTTTCTC
TTACCTGAAATGAACTATACTGAGGCAATAGGAGCTTTGTATAGTAATTTAGGAGTGTAAAACAACTTAGGGAAAAGGATTATTAAGCAGGATGATTGGG
ATGACATCATGTGAAATTTAGGAATTGGAGGCATTGGGAATTGAGAGGGTGCTAACAAAGGAAAACAGCTTATTTTAGAATTTGTCTGGAGGATGTAGAA
TTGAAGAAGTTTTGGTATTTCTTCTGCAGCGGCCCCAGTGCCCTTGACCAGGAACATCTCTTGGAGTCAGTAGTTTTCATGAGGCTGACCTAGGAACTTG
GCCAACATATGCAACATTGTTCTATTTAAAATATTCCTTGAATTAAATTCGATAGTATCAATTTAAAACATAAAGTTTTCACTCAACTCCTTTAGAAGTT
AGATTTTAGCTTGTACTTGTCTTTACCTCTTCTGCTGATTATCAGTTGACAACACTGAGATTACTTTCATTTTCCTGTAAGTCATTATGAATTTTTCTGG
TCAACCATGAGTTATCAGTGGAAGCAATAAGTAGGAAGTACTGTAAAAGAATTACAATAAAATAAGAGAAACCACTTGGAGAGCAAGAGGGCTTGTGGAC
TTGGGGGAGCGGTTGTGAGAAATGTCTCAGAACTTAATTTACAAATAACATTGGTAGATTGACATGTTGTCTTTCCTATAAAGTAACTTTACCTCTGTCT
TAATAGTAAACTACTATGAAAGTGAATTCGTGTTCCTCTTGATTTGTGAACTGATGAAAATTACAAAATGTGGAGTTTTTTCCCCAGATAAAGTAAATGG
TGGAATATTCAGGTTTATTTGATACCTAGAAAATACCTGAAATTTTCCGTGGTAATAGGCACATTTTGAAACTGTTTTTTTTTTCTCTGACAATTGAATA
TATTTTATATATAGTTGATTTTGATTATTGAAGACTAAGGAAAATTTAAGTTTGAATGTTAGAAAATGAATTTTGCAAATTTGAAGTAATTTTATTCTTT
ATGTTTTGGGATTGTAGTTATGTTAGATATTCCTCAGTTGGGGTAATTGTCTTGCATCATTATCTCTTATCATAATCTGTTTTTCTTCACACAGTGTTAT
AGTTTTGCCGCTGGACTCTTCCCTCCCTTCCCCCACCCCATCAGGATGATATGAGACTTGAAAGAAGACGATGCATACAGGAGGAGAGACTTCAGCATGC
AAACCTTCATCTGTTCGGCTTGCACCGTCATTTTCATTCCATGCTGCTGGCCTTCAGATGGCTGGACAGATGCCCCATTCACATCAGTACAGTGACCGTC
GCCAGCCAAACATAAGTGACCAACAGGTTTCTGCCTTATCATATTCTGACCAGATTCAGCAACCTCTAACTAACCAGGTGATGCCTGATATTGTCATGTT
ACAGAGGCGGATGCCCCAAACCTTCCGTGACCCAGCAACTGCTCCCCTGAGAAAACTTTCTGTTGACTTGATCAAAACATACAAGCATATTAATGAGGTT
TACTATGCAAAAAAGAAGCGAAGACACCAACAGGGCCAGGGAGACGATTCTAGTCATAAGAAGGAACGGAAGGTTTACAATGATGGTTATGATGATGATA
ACTATGATTATATTGTAAAAAACGGAGAAAAGTGGATGGATCGTTACGAAATTGACTCCTTGATAGGCAAAGGTTCCTTTGGACAGGTTGTAAAGGCATA
TGATCGTGTGGAGCAAGAATGGGTTGCCATTAAAATAATAAAGAACAAGAAGGCTTTTCTGAATCAAGCACAGATAGAAGTGCGACTTCTTGAGCTCATG
AACAAACATGACACTGAAATGAAATACTACATAGTGCATTTGAAACGCCACTTTATGTTTCGAAACCATCTCTGTTTAGTTTTTGAAATGCTGTCCTACA
ACCTCTATGACTTGCTGAGAAACACCAATTTCCGAGGGGTCTCTTTGAACCTAACACGAAAGTTTGCGCAACAGATGTGCACTGCACTGCTTTTCCTTGC
GACTCCAGAACTTAGTATCATTCACTGTGATCTAAAACCTGAAAATATCCTTCTTTGTAACCCCAAACGCAGTGCAATCAAGATAGTTGACTTTGGCAGT
TCTTGTCAGTTGGGGCAGAGGATATACCAGTATATTCAGAGTCGCTTTTATCGGTCTCCAGAGGTGCTACTGGGAATGCCTTATGACCTTGCCATTGATA
TGTGGTCCCTCGGGTGTATTTTGGTTGAAATGCACACTGGAGAACCTCTGTTCAGTGGTGCCAATGAGGTAGATCAGATGAATAAAATAGTGGAAGTTCT
GGGTATTCCACCTGCTCATATTCTTGACCAAGCACCAAAAGCAAGAAAGTTCTTTGAGAAGTTGCCAGATGGCACTTGGAACTTAAAGAAGACCAAAGAT
GGAAAACGGGAGTACAAACCACCAGGAACCCGTAAACTTCATAACATTCTTGGAGTGGAAACAGGAGGACCTGGTGGGCGACGTGCTGGGGAGTCAGGTC
ATACGGTCGCTGACTACTTGAAGTTCAAAGACCTCATTTTAAGGATGCTTGATTATGACCCCAAAACTCGAATTCAACCTTATTATGCTCTGCAGCACAG
TTTCTTCAAGAAAACAGCTGATGAAGGTACAAATACAAGTAATAGTGTATCTACAAGCCCCGCCATGGAGCAGTCTCAGTCTTCGGGCACCACCTCCAGT
ACATCGTCAAGCTCAG
GTGGAGCAGCACTGGATGCCAGGTGCCTTTAGAATGACCGTATCATTTACCCTAGAGGTTCATGACGTTCCTGTCTAAGGAAAT
GTGCGTCAGCAATTTCCTGCTCCTCTTGGTTGGTCAGGCACTGAAGCTCCTACACAGGTCACTGTTGAAACTCATCCTGTTCAAGAAACAACCTTTCATG
TAGCCCCTCAACAGAATGCATTGCATCATCACCATGGTAACAGTTCCCATCACCATCACCACCACCACCACCATCACCACCACCATGGACAACAAGCCTT
GGGTAACCGGACCAGGCCAAGGGTCTACAATTCTCCAACGAATAGCTCCTCTACCCAAGATTCTATGGAGGTTGGCCACAGTCACCACTCCATGACATCC
CTGTCTTCCTCAACGACTTCTTCCTCGACATCTTCCTCCTCTACTGGTAACCAAGGCAATCAGGCCTACCAGAATCGCCCAGTGGCTGCTAATACCTTGG
ACTTTGGACAGAATGGAGCTATGGACGTTAATTTGACCGTCTACTCCAATCCCCGCCAAGAGACTGGCATAGCTGGACATCCAACATACCAATTTTCTGC
TAATACAGGTCCTGCACATTACATGACTGAAGGACATCTGACAATGAGGCAAGGGGCTGATAGAGAAGAGTCCCCCATGACAGGAGTTTGTGTGCAACAG
AGTCCTGTAGCTAGCTCGTGACTACATTGAAACTTGAGTTTGTTTCTTGTGTGTTTTTATAGAAGTGGTGTTTTTTTTCCAAAAACAAAGTGCAAAGCTG
CTTGAATCAGGAGGAGATTAACACACTGAACCGCTACAAGAGGGCAAAGCTGATTTTTTTTTTAACTTGAAAAGATTGCAAAGGGACATTGAAGTGTTTA
AAAGAGCCATGTCCAAACCCATCTTCATGGATAGCTCAGAGGTATCCTCTTTTTGCTCCCCCATTTTAACTTGCCACATCCCAGTCACAGTGGGGTTTTT
TTGTCTTTCTATTCAGCAAAAGTTAATATTCAGATGTTGGTCTTGGTCATTTGCCAACTAATTTTAAAGTAAAAGGCACTGCACATAATTTGCATAAAGG
GCCCCATGAGGGTGTTTTTTTTTTTTCTTTTTGTCCCCCCCATCCCCCTTTTTTTTTGTTTTGTTCTGTTTTGTTTTGGGTGGGAGGGTGGGAAATTTGG
GTTTTTAAGTCCTCTAAACACACTTGGGCACGGAAATGCAGTACTGTAAGGAAGAGGGACCTCCAGCTTCCACAAACACCATCTTCAGCTGTATGAAAGG
GACGGTTGTGGTGAAGTTTGTCAGGCACAGTAAGCATGCTGAGTGGCGGGGATCAGAACTCTCCTATCTGAACCTACTGAGGAGCAAAGCAGCAATTACA
TGGGATCCTGTGGCTCTCCCGTTGCAGAGGCCACAGGAAGATAGGATGGAACGTGACTGGTCTCCTAACCAAGGTGCACTGAGAAGCAATCAACGGGTCG
GTCGTGGCCAGTCCTGGGGAGGTCTGAGTGGTGGTCTTTGGGATAACCTTTGGCCTTATGGATTTGGACTCGAAATTAGAAGAGCCTACCATTTCAGATG
CAATCACTTTTGGACATGCTTTTGCAGACAGTCCTTAATGCTGAAAACACAGAGAATGGGTAATTCAAGAGGCCTTTCTTTTAAAATAGACTTTTGTGAC
CCACTAATTGTAAGGTATTGCAAGGTCACTTTGCGTGTGTCATAAAGTTGACTTCCTTATTGGTTGAAGGTCACAGAAGTAGTGGTTTGCTTTGATGGAA
ATAGCTACAGCTGTGTCCCTTCCTGCTTTTTACTTTTTCTTTTGCTTTTTCTCGGCACGTGGTATCTCCACCATTTCTTCTGCACAAAGATGTCTTCTGT
TCATCCTGAACATTTTTAAAAAATGCAGAATTTTATGTGACTGCTTTTTTGCCTCACAATTATGCTGTGAATTTTACAAAAATTTATTTTCTTTTTTGAT
AATTTATTGTACCAAAGCTGTTTTTATAGCACATAGATGTCTGTAACCAATAATGTAGCAGTTCTGCACTTTGACACAAGGTGTAACTAGACCATTTTTA
AATGTCAGTTGAAAATTATGGCTGTACTATTGCTTAAACAAAACTGGAACTGTTGTTGAATCCATAGCCAATACATTTACAGCAATCTGTGTACTGAACA
TAGTAGATTGACATCTAATTCAAGATTACAACATCTGTTACATTCTAAGTGTGTTCAGGCTTCTGAAGGTAAAGGGACACTGGATCCAGAAGCTATGGAA
CCAGCAGTTGATTCTTGTATTCCTGATTAACCTACTTGTAAACTTGAAAGCAAGACCTTGATTGCACCAACAGGTCCAGAGTATGAGTGCAAGCAAAGCA
GAACTCTCATGCGTGACCTGAGCAGACAGGCTGGTATTTAACAGGTGCCTCGTGTTGAGATTACGCTGCCTTAATGTAACACAGTCTGGCAGTTGCTAAA
TTTGTGTTCCCATTTTAAATTGACCAATTTTGGGGTGTGACACTTTTGAGCGGTTGAATTGGGAGAATGAAGATAAGTAATTTACCTGTCCAGGATCAAA
AGAAGCCTAGAAAAGAAGCAGTAATCTACCTCTGCCGATAACCTGTTTAAGATGACTCAGCAGAACACCGCGTTTCATTCTATTGGTCAATTCCATGTGG
CTGACTAGGTCAATTTTTTTTCTGAACAAAAGCAGGTTTTTATATGTAAACAGTGAGAAAAGAAAGGCTAAACACTATGTAAATGTGAATGGAAACTTGG
AAATACTCGTTTTTATAAACTACAAAAACTTTTTGTTGTTTATCAGGAAATCCATATTTATTTTGTAATTAACTGTCAAGCCTGTGGATGATTTTTTTGA
ACTTGGTAGTTCATAAAGGTTTACAGTGAATAAAAGGATATCATCTTGAGTATAGCAATATCAAAAGGAATTCAGTAGTTACTGCTGTTTAGGAATATAA
GGTTAAGATATCATATGGGTCAGGTCATTTTTTTTTTCTGTGCTGGTTGCCACATCTTAGCAAGCACCAAAAAACTAAAGCAGTTTTTAAACCGATATTT
ACGTAAAGAAAATCATAAAATCCAATGCTTCTGCATACTGTGTTATGTTACAGTCCAGTTTTGTGTGCTTTACTACACAGTTTGGTTACAGGACTTCTGT
GCATTGTAAACATAAACAGCATGGAAAAGGTTAAATACCTGTGTTCAGATTGTAAGATCTAGTCCGGACTTGCTGTGTATATTGTAACGTTAAATGAAAA
AAGAACCCCCCTTTGTATTATAGTCATGCGGTCTTATGTATGATAAACAGTTGAATAATTTGTC
  • refseq_DYRK1A.F5 (forward primer)
  • refseq_DYRK1A.R5 (reverse primer)
  • Alternative acceptor

Frame 0

KNNSYCL*GSFPVKCLVLLLFGVQSWSF*RTWE
FKSIRRNK*KAEIF*GNKYRLKSIL*PTCSTTWN
STNKRFIWANYNGCWKLQILV*IILVQLVSFFL
LPEMNYTEAIGALYSNLGV*NNLGKRIIKQDDW
DDIM*NLGIGGIGN*EGANKGKQLILEFVWRM*N
*RSFGISSAAAPVPLTRNISWSQ*FS*G*PRNL
ANICNIVLFKIFLELNSIVSI*NIKFSLNSFRS
*ILACTCLYLFC*LSVDNTEITFIFL*VIMNFSG
QP*VISGSNK*EVL*KNYNKIRETTWRARGLVD
LGERL*EMSQNLIYK*HW*IDMLSFL*SNFTSV
LIVNYYESEFVFLLICELMKITKCGVFSPDKVNG
GIFRFI*YLENT*NFPW**AHFETVFFFSDN*I
YFIYS*F*LLKTKENLSLNVRK*ILQI*SNFIL
YVLGL*LC*IFLSWGNCLASLSLIIICFSSHSVI
VLPLDSSLPSPTPSG*YET*KKTMHTGGETSAC
KPSSVRLAPSFSFHAAGLQMAGQMPHSHQYSDR
RQPNISDQQVSALSYSDQIQQPLTNQVMPDIVML
QRRMPQTFRDPATAPLRKLSVDLIKTYKHINEV
YYAKKKRRHQQGQGDDSSHKKERKVYNDGYDDD
NYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAY
DRVEQEWVAIKIIKNKKAFLNQAQIEVRLLELM
NKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSY
NLYDLLRNTNFRGVSLNLTRKFAQQMCTALLFLA
TPELSIIHCDLKPENILLCNPKRSAIKIVDFGS
SCQLGQRIYQYIQSRFYRSPEVLLGMPYDLAID
MWSLGCILVEMHTGEPLFSGANEVDQMNKIVEVL
GIPPAHILDQAPKARKFFEKLPDGTWNLKKTKD
GKREYKPPGTRKLHNILGVETGGPGGRRAGESG
HTVADYLKFKDLILRMLDYDPKTRIQPYYALQHS
FFKKTADEGTNTSNSVSTSPAMEQSQSSGTTSS
TSSSS
GGAALDARCL*NDRIIYPRGS*RSCLRK
CASAISCSSWLVRH*SSYTGHC*NSSCSRNNLSC
SPSTECIASSPW*QFPSPSPPPPPSPPPWTTSL
G*PDQAKGLQFSNE*LLYPRFYGGWPQSPLHDI
PVFLNDFFLDIFLLYW*PRQSGLPESPSGC*YLG
LWTEWSYGR*FDRLLQSPPRDWHSWTSNIPIFC
*YRSCTLHD*RTSDNEARG**RRVPHDRSLCAT
ESCS*LVTTLKLEFVSCVFL*KWCFFSKNKVQSC
LNQEEINTLNRYKRAKLIFFLT*KDCKGTLKCL
KEPCPNPSSWIAQRYPLFAPPF*LATSQSQWGF
FVFLFSKS*YSDVGLGHLPTNFKVKGTAHNLHKG
PHEGVFFFSFCPPHPPFFLFCSVLFWVGGWEIW
VFKSSKHTWARKCSTVRKRDLQLPQTPSSAV*K
GRLW*SLSGTVSMLSGGDQNSPI*TY*GAKQQLH
GILWLSRCRGHRKIGWNVTGLLTKVH*EAINGS
VVASPGEV*VVVFGITFGLMDLDSKLEEPTISD
AITFGHAFADSP*C*KHREWVIQEAFLLK*TFVT
H*L*GIARSLCVCHKVDFLIG*RSQK*WFALME
IATAVSLPAFYFFFCFFSARGISTISSAQRCLL
FILNIFKKCRILCDCFFASQLCCEFYKNLFSFLI
IYCTKAVFIAHRCL*PIM*QFCTLTQGVTRPFL
NVS*KLWLYYCLNKTGTVVESIANTFTAICVLN
IVD*HLIQDYNICYILSVFRLLKVKGHWIQKLWN
QQLILVFLINLLVNLKARP*LHQQVQSMSASKA
ELSCVT*ADRLVFNRCLVLRLRCLNVTQSGSC*
ICVPILN*PILGCDTFERLNWENEDK*FTCPGSK
EA*KRSSNLPLPITCLR*LSRTPRFILLVNSMW
LTRSIFFLNKSRFLYVNSEKRKAKHYVNVNGNL
EILVFINYKNFLLFIRKSIFIL*LTVKPVDDFFE
LGSS*RFTVNKRISS*V*QYQKEFSSYCCLGI*
G*DIIWVRSFFFSVLVATS*QAPKN*SSF*TDI
YVKKIIKSNASAYCVMLQSSFVCFTTQFGYRTSV
HCKHKQHGKG*IPVFRL*DLVRTCCVYCNVK*K
KNPPLYYSHAVLCMINS*IIC

Frame 1

KITHIVSEVLFQ*SV*YCCYLEYKVGAFKEPGS
SKV*GEINEKQKYFEAISIDSNLYYDPLVAPLG
ILPIRDLFGQTIMVVGNCKS*CELF*SSWFLSFS
YLK*TILRQ*ELCIVI*ECKTT*GKGLLSRMIG
MTSCEI*ELEALGIERVLTKENSLF*NLSGGCR
IEEVLVFLLQRPQCP*PGTSLGVSSFHEADLGTW
PTYATLFYLKYSLN*IR*YQFKT*SFHSTPLEV
RF*LVLVFTSSADYQLTTLRLLSFSCKSL*IFL
VNHELSVEAISRKYCKRITIK*EKPLGEQEGLWT
WGSGCEKCLRT*FTNNIGRLTCCLSYKVTLPLS
***TTMKVNSCSS*FVN**KLQNVEFFPQIK*M
VEYSGLFDT*KIPEIFRGNRHILKLFFFSLTIEY
ILYIVDFDY*RLRKI*V*MLENEFCKFEVILFF
MFWDCSYVRYSSVGVIVLHHYLLS*SVFLHTVL
*FCRWTLPSLPPPHQDDMRLERRRCIQEERLQHA
NLHLFGLHRHFHSMLLAFRWLDRCPIHISTVTV
ASQT*VTNRFLPYHILTRFSNL*LTR*CLILSC
YRGGCPKPSVTQQLLP*ENFLLT*SKHTSILMRF
TMQKRSEDTNRARETILVIRRNGRFTMMVMMMI
TMIIL*KTEKSGWIVTKLTP**AKVPLDRL*RH
MIVWSKNGLPLK**RTRRLF*IKHR*KCDFLSS*
TNMTLK*NTT*CI*NATLCFETISV*FLKCCPT
TSMTC*ETPISEGSL*T*HESLRNRCALHCFSL
RLQNLVSFTVI*NLKISFFVTPNAVQSR*LTLAV
LVSWGRGYTSIFRVAFIGLQRCYWECLMTLPLI
CGPSGVFWLKCTLENLCSVVPMR*IR*IK*WKF
WVFHLLIFLTKHQKQESSLRSCQMALGT*RRPKM
ENGSTNHQEPVNFITFLEWKQEDLVGDVLGSQV
IRSLTT*SSKTSF*GCLIMTPKLEFNLIMLCST
VSSRKQLMKVQIQVIVYLQAPPWSSLSLRAPPPV
HRQAQ
VEQHWMPGAFRMTVSFTLEVHDVPV*GN
VRQQFPAPLGWSGTEAPTQVTVETHPVQETTFH
VAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQAL
GNRTRPRVYNSPTNSSSTQDSMEVGHSHHSMTS
LSSSTTSSSTSSSSTGNQGNQAYQNRPVAANTL
DFGQNGAMDVNLTVYSNPRQETGIAGHPTYQFSA
NTGPAHYMTEGHLTMRQGADREESPMTGVCVQQ
SPVASS*LH*NLSLFLVCFYRSGVFFPKTKCKA
A*IRRRLTH*TATRGQS*FFF*LEKIAKGH*SV*
KSHVQTHLHG*LRGILFLLPHFNLPHPSHSGVF
LSFYSAKVNIQMLVLVICQLILK*KALHIICIK
GPMRVFFFFLFVPPIPLFFCFVLFCFGWEGGKFG
FLSPLNTLGHGNAVL*GRGTSSFHKHHLQLYER
DGCGEVCQAQ*AC*VAGIRTLLSEPTEEQSSNY
MGSCGSPVAEATGR*DGT*LVS*PRCTEKQSTGR
SWPVLGRSEWWSLG*PLALWIWTRN*KSLPFQM
QSLLDMLLQTVLNAENTENG*FKRPFF*NRLL*
PTNCKVLQGHFACVIKLTSLLVEGHRSSGLL*WK
*LQLCPFLLFTFSFAFSRHVVSPPFLLHKDVFC
SS*TFLKNAEFYVTAFLPHNYAVNFTKIYFLF*
*FIVPKLFL*HIDVCNQ*CSSSAL*HKV*LDHF*
MSVENYGCTIA*TKLELLLNP*PIHLQQSVY*T
**IDI*FKITTSVTF*VCSGF*R*RDTGSRSYG
TSS*FLYS*LTYL*T*KQDLDCTNRSRV*VQAKQ
NSHA*PEQTGWYLTGASC*DYAALM*HSLAVAK
FVFPF*IDQFWGVTLLSG*IGRMKISNLPVQDQ
KKPRKEAVIYLCR*PV*DDSAEHRVSFYWSIPCG
*LGQFFF*TKAGFYM*TVRKERLNTM*M*METW
KYSFL*TTKTFCCLSGNPYLFCN*LSSLWMIFL
NLVVHKGLQ*IKGYHLEYSNIKRNSVVTAV*EYK
VKISYGSGHFFFLCWLPHLSKHQKTKAVFKPIF
T*RKS*NPMLLHTVLCYSPVLCALLHSLVTGLL
CIVNINSMEKVKYLCSDCKI*SGLAVYIVTLNEK
RTPLCIIVMRSYV**TVE*FV

Frame 2

K*LILSLRFFSSEVFSIAAIWSTKLELLKNLGV
QKYKEK*MKSRNILRQ*V*TQIYIMTHL*HHLE
FYQ*EIYLGKL*WLLEIANLSVNYFSPVGFFLS
LT*NELY*GNRSFV**FRSVKQLREKDY*AG*LG
*HHVKFRNWRHWELRGC*QRKTAYFRICLEDVE
LKKFWYFFCSGPSALDQEHLLESVVFMRLT*EL
GQHMQHCSI*NIP*IKFDSINLKHKVFTQLL*KL
DFSLYLSLPLLLIIS*QH*DYFHFPVSHYEFFW
STMSYQWKQ*VGSTVKELQ*NKRNHLESKRACG
LGGAVVRNVSELNLQITLVD*HVVFPIK*LYLCL
NSKLL*K*IRVPLDL*TDENYKMWSFFPR*SKW
WNIQVYLIPRKYLKFSVVIGTF*NCFFFL*QLN
IFYI*LILIIED*GKFKFEC*KMNFANLK*FYSL
CFGIVVMLDIPQLG*LSCIIISYHNLFFFTQCY
SFAAGLFPPFPHPIRMI*DLKEDDAYRRRDFSM
QTFICSACTVIFIPCCWPSDGWTDAPFTSVQ*PS
PAKHK*PTGFCLIIF*PDSATSN*PGDA*YCHV
TEADAPNLP*PSNCSPEKTFC*LDQNIQAY**G
LLCKKEAKTPTGPGRRF*S*EGTEGLQ*WL****
L*LYCKKRRKVDGSLRN*LLDRQRFLWTGCKGI
*SCGARMGCH*NNKEQEGFSESSTDRSATS*AH
EQT*H*NEILHSAFETPLYVSKPSLFSF*NAVLQ
PL*LAEKHQFPRGLFEPNTKVCATDVHCTAFPC
DSRT*YHSL*SKT*KYPSL*PQTQCNQDS*LWQ
FLSVGAEDIPVYSESLLSVSRGATGNAL*PCH*Y
VVPRVYFG*NAHWRTSVQWCQ*GRSDE*NSGSS
GYSTCSYS*PSTKSKKVL*EVARWHLELKEDQR
WKTGVQTTRNP*TS*HSWSGNRRTWWATCWGVRS
YGR*LLEVQRPHFKDA*L*PQNSNSTLLCSAAQ
FLQENS**RYKYK**CIYKPRHGAVSVFGHHLQ
YIVKLR
WSSTGCQVPLE*PYHLP*RFMTFLSKEM
CVSNFLLLLVGQALKLLHRSLLKLILFKKQPFM
*PLNRMHCIITMVTVPITITTTTTITTTMDNKP
WVTGPGQGSTILQRIAPLPKILWRLATVTTP*HP
CLPQRLLPRHLPPLLVTKAIRPTRIAQWLLIPW
TLDRMELWTLI*PSTPIPAKRLA*LDIQHTNFL
LIQVLHIT*LKDI*Q*GKGLIEKSPP*QEFVCNR
VL*LARDYIET*VCFLCVFIEVVFFFQKQSAKL
LESGGD*HTEPLQEGKADFFFNLKRLQRDIEVF
KRAMSKPIFMDSSEVSSFCSPILTCHIPVTVGFF
CLSIQQKLIFRCWSWSFAN*F*SKRHCT*FA*R
AP*GCFFFFFLSPPSPFFFVLFCFVLGGRVGNL
GF*VL*THLGTEMQYCKEEGPPASTNTIFSCMKG
TVVVKFVRHSKHAEWRGSELSYLNLLRSKAAIT
WDPVALPLQRPQEDRMERDWSPNQGALRSNQRV
GRGQSWGGLSGGLWDNLWPYGFGLEIRRAYHFRC
NHFWTCFCRQSLMLKTQRMGNSRGLSFKIDFCD
PLIVRYCKVTLRVS*S*LPYWLKVTEVVVCFDG
NSYSCVPSCFLLFLLLFLGTWYLHHFFCTKMSSV
HPEHF*KMQNFM*LLFCLTIML*ILQKFIFFFD
NLLYQSCFYST*MSVTNNVAVLHFDTRCN*TIF
KCQLKIMAVLLLKQNWNCC*IHSQYIYSNLCTEH
SRLTSNSRLQHLLHSKCVQASEGKGTLDPEAME
PAVDSCIPD*PTCKLESKTLIAPTGPEYECKQS
RTLMRDLSRQAGI*QVPRVEITLP*CNTVWQLLN
LCSHFKLTNFGV*HF*AVELGE*R*VIYLSRIK
RSLEKKQ*STSADNLFKMTQQNTAFHSIGQFHV
AD*VNFFSEQKQVFICKQ*EKKG*TLCKCEWKLG
NTRFYKLQKLFVVYQEIHIYFVINCQACG*FF*
TW*FIKVYSE*KDIILSIAISKGIQ*LLLFRNI
RLRYHMGQVIFFFCAGCHILASTKKLKQFLNRYL
RKENHKIQCFCILCYVTVQFCVLYYTVWLQDFC
AL*T*TAWKRLNTCVQIVRSSPDLLCIL*R*MK
KEPPFVL*SCGLMYDKQLNNL

Sequence NM_101395

GGGAGCGCGGCGCGGGAGCCCGAGGCTGAGACTCACCGGAGGAAGCGGCGCGAGCGCCCCGCCATCGTCCCGGCTGAAGTGCAGTGGCACGATCATAGGT
GGTCACTACAGTCTCAGATTCCTGGGCTTAAGCAGTCTTCCCACCTCAGCCTCCCCAGTAGCTGGGATTACAGTGTTATAGTTTTGCCGCTGGACTCTTC
CCTCCCTTCCCCCACCCCATCAGGATGATATGAGACTTGAAAGAAGACGATGCATACAGGAGGAGAGACTTCAGCATGCAAACCTTCATCTGTTCGGCTT
GCACCGTCATTTTCATTCCATGCTGCTGGCCTTCAGATGGCTGGACAGATGCCCCATTCACATCAGTACAGTGACCGTCGCCAGCCAAACATAAGTGACC
AACAGGTTTCTGCCTTATCATATTCTGACCAGATTCAGCAACCTCTAACTAACCAGGTGATGCCTGATATTGTCATGTTACAGAGGCGGATGCCCCAAAC
CTTCCGTGACCCAGCAACTGCTCCCCTGAGAAAACTTTCTGTTGACTTGATCAAAACATACAAGCATATTAATGAGGTTTACTATGCAAAAAAGAAGCGA
AGACACCAACAGGGCCAGGGAGACGATTCTAGTCATAAGAAGGAACGGAAGGTTTACAATGATGGTTATGATGATGATAACTATGATTATATTGTAAAAA
ACGGAGAAAAGTGGATGGATCGTTACGAAATTGACTCCTTGATAGGCAAAGGTTCCTTTGGACAGGTTGTAAAGGCATATGATCGTGTGGAGCAAGAATG
GGTTGCCATTAAAATAATAAAGAACAAGAAGGCTTTTCTGAATCAAGCACAGATAGAAGTGCGACTTCTTGAGCTCATGAACAAACATGACACTGAAATG
AAATACTACATAGTGCATTTGAAACGCCACTTTATGTTTCGAAACCATCTCTGTTTAGTTTTTGAAATGCTGTCCTACAACCTCTATGACTTGCTGAGAA
ACACCAATTTCCGAGGGGTCTCTTTGAACCTAACACGAAAGTTTGCGCAACAGATGTGCACTGCACTGCTTTTCCTTGCGACTCCAGAACTTAGTATCAT
TCACTGTGATCTAAAACCTGAAAATATCCTTCTTTGTAACCCCAAACGCAGTGCAATCAAGATAGTTGACTTTGGCAGTTCTTGTCAGTTGGGGCAGAGG
ATATACCAGTATATTCAGAGTCGCTTTTATCGGTCTCCAGAGGTGCTACTGGGAATGCCTTATGACCTTGCCATTGATATGTGGTCCCTCGGGTGTATTT
TGGTTGAAATGCACACTGGAGAACCTCTGTTCAGTGGTGCCAATGAGGTAGATCAGATGAATAAAATAGTGGAAGTTCTGGGTATTCCACCTGCTCATAT
TCTTGACCAAGCACCAAAAGCAAGAAAGTTCTTTGAGAAGTTGCCAGATGGCACTTGGAACTTAAAGAAGACCAAAGATGGAAAACGGGAGTACAAACCA
CCAGGAACCCGTAAACTTCATAACATTCTTGGAGTGGAAACAGGAGGACCTGGTGGGCGACGTGCTGGGGAGTCAGGTCATACGGTCGCTGACTACTTGA
AGTTCAAAGACCTCATTTTAAGGATGCTTGATTATGACCCCAAAACTCGAATTCAACCTTATTATGCTCTGCAGCACAGTTTCTTCAAGAAAACAGCTGA
TGAAGGTACAAATACAAGTAATAGTGTATCTACAAGCCCCGCCATGGAGCAGTCTCAGTCTTCGGGCACCACCTCCAGTACATCGTCAAGCTCAGGTGGC
TCATCGGGGACAAGCAACAGTGGGAGAGCCCGGTCGGATCCGACGCACCAGCATCGGCACAGTGGTGGGCACTTCACAGCTGCCGTGCAGGCCATGGACT
GCGAGACACACAGTCCCCAGGTGAGCTCGCACGTGGTTCATTTGCTTGTGTCACCTGCCATTCTCAG
GTGGAGCAGCACTGGATGCCAGGTGCCTTTAGA
ATGACCGTATCATTTACCCTAGAGGTTCATGACGTTCCTGTCTAAGGAAATGTGCGTCAGCAATTTCCTGCTCCTCTTGGTTGGTCAGGCACTGAAGCTC
CTACACAGGTCACTGTTGAAACTCATCCTGTTCAAGAAACAACCTTTCATGTAGCCCCTCAACAGAATGCATTGCATCATCACCATGGTAACAGTTCCCA
TCACCATCACCACCACCACCACCATCACCACCACCATGGACAACAAGCCTTGGGTAACCGGACCAGGCCAAGGGTCTACAATTCTCCAACGAATAGCTCC
TCTACCCAAGATTCTATGGAGGTTGGCCACAGTCACCACTCCATGACATCCCTGTCTTCCTCAACGACTTCTTCCTCGACATCTTCCTCCTCTACTGGTA
ACCAAGGCAATCAGGCCTACCAGAATCGCCCAGTGGCTGCTAATACCTTGGACTTTGGACAGAATGGAGCTATGGACGTTAATTTGACCGTCTACTCCAA
TCCCCGCCAAGAGACTGGCATAGCTGGACATCCAACATACCAATTTTCTGCTAATACAGGTCCTGCACATTACATGACTGAAGGACATCTGACAATGAGG
CAAGGGGCTGATAGAGAAGAGTCCCCCATGACAGGAGTTTGTGTGCAACAGAGTCCTGTAGCTAGCTCGTGACTACATTGAAACTTGAGTTTGTTTCTTG
TGTGTTTTTATAGAAGTGGTGTTTTTTTTCCAAAAACAAAGTGCAAAGCTGCTTGAATCAGGAGGAGATTAACACACTGAACCGCTACAAGAGGGCAAAG
CTGATTTTTTTTTTAACTTGAAAAGATTGCAAAGGGACATTGAAGTGTTTAAAAGAGCCATGTCCAAACCCATCTTCATGGATAGCTCAGAGGTATCCTC
TTTTTGCTCCCCCATTTTAACTTGCCACATCCCAGTCACAGTGGGGTTTTTTTGTCTTTCTATTCAGCAAAAGTTAATATTCAGATGTTGGTCTTGGTCA
TTTGCCAACTAATTTTAAAGTAAAAGGCACTGCACATAATTTGCATAAAGGGCCCCATGAGGGTGTTTTTTTTTTTTCTTTTTGTCCCCCCCATCCCCCT
TTTTTTTTGTTTTGTTCTGTTTTGTTTTGGGTGGGAGGGTGGGAAATTTGGGTTTTTAAGTCCTCTAAACACACTTGGGCACGGAAATGCAGTACTGTAA
GGAAGAGGGACCTCCAGCTTCCACAAACACCATCTTCAGCTGTATGAAAGGGACGGTTGTGGTGAAGTTTGTCAGGCACAGTAAGCATGCTGAGTGGCGG
GGATCAGAACTCTCCTATCTGAACCTACTGAGGAGCAAAGCAGCAATTACATGGGATCCTGTGGCTCTCCCGTTGCAGAGGCCACAGGAAGATAGGATGG
AACGTGACTGGTCTCCTAACCAAGGTGCACTGAGAAGCAATCAACGGGTCGGTCGTGGCCAGTCCTGGGGAGGTCTGAGTGGTGGTCTTTGGGATAACCT
TTGGCCTTATGGATTTGGACTCGAAATTAGAAGAGCCTACCATTTCAGATGCAATCACTTTTGGACATGCTTTTGCAGACAGTCCTTAATGCTGAAAACA
CAGAGAATGGGTAATTCAAGAGGCCTTTCTTTTAAAATAGACTTTTGTGACCCACTAATTGTAAGGTATTGCAAGGTCACTTTGCGTGTGTCATAAAGTT
GACTTCCTTATTGGTTGAAGGTCACAGAAGTAGTGGTTTGCTTTGATGGAAATAGCTACAGCTGTGTCCCTTCCTGCTTTTTACTTTTTCTTTTGCTTTT
TCTCGGCACGTGGTATCTCCACCATTTCTTCTGCACAAAGATGTCTTCTGTTCATCCTGAACATTTTTAAAAAATGCAGAATTTTATGTGACTGCTTTTT
TGCCTCACAATTATGCTGTGAATTTTACAAAAATTTATTTTCTTTTTTGATAATTTATTGTACCAAAGCTGTTTTTATAGCACATAGATGTCTGTAACCA
ATAATGTAGCAGTTCTGCACTTTGACACAAGGTGTAACTAGACCATTTTTAAATGTCAGTTGAAAATTATGGCTGTACTATTGCTTAAACAAAACTGGAA
CTGTTGTTGAATCCATAGCCAATACATTTACAGCAATCTGTGTACTGAACATAGTAGATTGACATCTAATTCAAGATTACAACATCTGTTACATTCTAAG
TGTGTTCAGGCTTCTGAAGGTAAAGGGACACTGGATCCAGAAGCTATGGAACCAGCAGTTGATTCTTGTATTCCTGATTAACCTACTTGTAAACTTGAAA
GCAAGACCTTGATTGCACCAACAGGTCCAGAGTATGAGTGCAAGCAAAGCAGAACTCTCATGCGTGACCTGAGCAGACAGGCTGGTATTTAACAGGTGCC
TCGTGTTGAGATTACGCTGCCTTAATGTAACACAGTCTGGCAGTTGCTAAATTTGTGTTCCCATTTTAAATTGACCAATTTTGGGGTGTGACACTTTTGA
GCGGTTGAATTGGGAGAATGAAGATAAGTAATTTACCTGTCCAGGATCAAAAGAAGCCTAGAAAAGAAGCAGTAATCTACCTCTGCCGATAACCTGTTTA
AGATGACTCAGCAGAACACCGCGTTTCATTCTATTGGTCAATTCCATGTGGCTGACTAGGTCAATTTTTTTTCTGAACAAAAGCAGGTTTTTATATGTAA
ACAGTGAGAAAAGAAAGGCTAAACACTATGTAAATGTGAATGGAAACTTGGAAATACTCGTTTTTATAAACTACAAAAACTTTTTGTTGTTTATCAGGAA
ATCCATATTTATTTTGTAATTAACTGTCAAGCCTGTGGATGATTTTTTTGAACTTGGTAGTTCATAAAGGTTTACAGTGAATAAAAGGATATCATCTTGA
GTATAGCAATATCAAAAGGAATTCAGTAGTTACTGCTGTTTAGGAATATAAGGTTAAGATATCATATGGGTCAGGTCATTTTTTTTTTCTGTGCTGGTTG
CCACATCTTAGCAAGCACCAAAAAACTAAAGCAGTTTTTAAACCGATATTTACGTAAAGAAAATCATAAAATCCAATGCTTCTGCATACTGTGTTATGTT
ACAGTCCAGTTTTGTGTGCTTTACTACACAGTTTGGTTACAGGACTTCTGTGCATTGTAAACATAAACAGCATGGAAAAGGTTAAATACCTGTGTTCAGA
TTGTAAGATCTAGTCCGGACTTGCTGTGTATATTGTAACGTTAAATGAAAAAAGAACCCCCCTTTGTATTATAGTCATGCGGTCTTATGTATGATAAACA
GTTGAATAATTTGTC
  • refseq_DYRK1A.F5 (forward primer)
  • refseq_DYRK1A.R5 (reverse primer)
  • Alternative acceptor

Frame 0

GSAAREPEAETHRRKRRERPAIVPAEVQWHDHR
WSLQSQIPGLKQSSHLSLPSSWDYSVIVLPLDSS
LPSPTPSG*YET*KKTMHTGGETSACKPSSVRL
APSFSFHAAGLQMAGQMPHSHQYSDRRQPNISD
QQVSALSYSDQIQQPLTNQVMPDIVMLQRRMPQT
FRDPATAPLRKLSVDLIKTYKHINEVYYAKKKR
RHQQGQGDDSSHKKERKVYNDGYDDDNYDYIVK
NGEKWMDRYEIDSLIGKGSFGQVVKAYDRVEQEW
VAIKIIKNKKAFLNQAQIEVRLLELMNKHDTEM
KYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLR
NTNFRGVSLNLTRKFAQQMCTALLFLATPELSII
HCDLKPENILLCNPKRSAIKIVDFGSSCQLGQR
IYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCI
LVEMHTGEPLFSGANEVDQMNKIVEVLGIPPAHI
LDQAPKARKFFEKLPDGTWNLKKTKDGKREYKP
PGTRKLHNILGVETGGPGGRRAGESGHTVADYL
KFKDLILRMLDYDPKTRIQPYYALQHSFFKKTAD
EGTNTSNSVSTSPAMEQSQSSGTTSSTSSSSGG
SSGTSNSGRARSDPTHQHRHSGGHFTAAVQAMD
CETHSPQVSSHVVHLLVSPAILR
WSSTGCQVPLE
*PYHLP*RFMTFLSKEMCVSNFLLLLVGQALKL
LHRSLLKLILFKKQPFM*PLNRMHCIITMVTVP
ITITTTTTITTTMDNKPWVTGPGQGSTILQRIAP
LPKILWRLATVTTP*HPCLPQRLLPRHLPPLLV
TKAIRPTRIAQWLLIPWTLDRMELWTLI*PSTP
IPAKRLA*LDIQHTNFLLIQVLHIT*LKDI*Q*G
KGLIEKSPP*QEFVCNRVL*LARDYIET*VCFL
CVFIEVVFFFQKQSAKLLESGGD*HTEPLQEGK
ADFFFNLKRLQRDIEVFKRAMSKPIFMDSSEVSS
FCSPILTCHIPVTVGFFCLSIQQKLIFRCWSWS
FAN*F*SKRHCT*FA*RAP*GCFFFFFLSPPSP
FFFVLFCFVLGGRVGNLGF*VL*THLGTEMQYCK
EEGPPASTNTIFSCMKGTVVVKFVRHSKHAEWR
GSELSYLNLLRSKAAITWDPVALPLQRPQEDRM
ERDWSPNQGALRSNQRVGRGQSWGGLSGGLWDNL
WPYGFGLEIRRAYHFRCNHFWTCFCRQSLMLKT
QRMGNSRGLSFKIDFCDPLIVRYCKVTLRVS*S
*LPYWLKVTEVVVCFDGNSYSCVPSCFLLFLLLF
LGTWYLHHFFCTKMSSVHPEHF*KMQNFM*LLF
CLTIML*ILQKFIFFFDNLLYQSCFYST*MSVT
NNVAVLHFDTRCN*TIFKCQLKIMAVLLLKQNWN
CC*IHSQYIYSNLCTEHSRLTSNSRLQHLLHSK
CVQASEGKGTLDPEAMEPAVDSCIPD*PTCKLE
SKTLIAPTGPEYECKQSRTLMRDLSRQAGI*QVP
RVEITLP*CNTVWQLLNLCSHFKLTNFGV*HF*
AVELGE*R*VIYLSRIKRSLEKKQ*STSADNLF
KMTQQNTAFHSIGQFHVAD*VNFFSEQKQVFICK
Q*EKKG*TLCKCEWKLGNTRFYKLQKLFVVYQE
IHIYFVINCQACG*FF*TW*FIKVYSE*KDIIL
SIAISKGIQ*LLLFRNIRLRYHMGQVIFFFCAGC
HILASTKKLKQFLNRYLRKENHKIQCFCILCYV
TVQFCVLYYTVWLQDFCAL*T*TAWKRLNTCVQ
IVRSSPDLLCIL*R*MKKEPPFVL*SCGLMYDKQ
LNNL

Frame 1

GARRGSPRLRLTGGSGASAPPSSRLKCSGTIIG
GHYSLRFLGLSSLPTSASPVAGITVL*FCRWTL
PSLPPPHQDDMRLERRRCIQEERLQHANLHLFGL
HRHFHSMLLAFRWLDRCPIHISTVTVASQT*VT
NRFLPYHILTRFSNL*LTR*CLILSCYRGGCPK
PSVTQQLLP*ENFLLT*SKHTSILMRFTMQKRSE
DTNRARETILVIRRNGRFTMMVMMMITMIIL*K
TEKSGWIVTKLTP**AKVPLDRL*RHMIVWSKN
GLPLK**RTRRLF*IKHR*KCDFLSS*TNMTLK*
NTT*CI*NATLCFETISV*FLKCCPTTSMTC*E
TPISEGSL*T*HESLRNRCALHCFSLRLQNLVS
FTVI*NLKISFFVTPNAVQSR*LTLAVLVSWGRG
YTSIFRVAFIGLQRCYWECLMTLPLICGPSGVF
WLKCTLENLCSVVPMR*IR*IK*WKFWVFHLLI
FLTKHQKQESSLRSCQMALGT*RRPKMENGSTNH
QEPVNFITFLEWKQEDLVGDVLGSQVIRSLTT*
SSKTSF*GCLIMTPKLEFNLIMLCSTVSSRKQL
MKVQIQVIVYLQAPPWSSLSLRAPPPVHRQAQVA
HRGQATVGEPGRIRRTSIGTVVGTSQLPCRPWT
ARHTVPR*ARTWFICLCHLPFS
GGAALDARCL*
NDRIIYPRGS*RSCLRKCASAISCSSWLVRH*SS
YTGHC*NSSCSRNNLSCSPSTECIASSPW*QFP
SPSPPPPPSPPPWTTSLG*PDQAKGLQFSNE*L
LYPRFYGGWPQSPLHDIPVFLNDFFLDIFLLYW*
PRQSGLPESPSGC*YLGLWTEWSYGR*FDRLLQ
SPPRDWHSWTSNIPIFC*YRSCTLHD*RTSDNE
ARG**RRVPHDRSLCATESCS*LVTTLKLEFVSC
VFL*KWCFFSKNKVQSCLNQEEINTLNRYKRAK
LIFFLT*KDCKGTLKCLKEPCPNPSSWIAQRYP
LFAPPF*LATSQSQWGFFVFLFSKS*YSDVGLGH
LPTNFKVKGTAHNLHKGPHEGVFFFSFCPPHPP
FFLFCSVLFWVGGWEIWVFKSSKHTWARKCSTV
RKRDLQLPQTPSSAV*KGRLW*SLSGTVSMLSGG
DQNSPI*TY*GAKQQLHGILWLSRCRGHRKIGW
NVTGLLTKVH*EAINGSVVASPGEV*VVVFGIT
FGLMDLDSKLEEPTISDAITFGHAFADSP*C*KH
REWVIQEAFLLK*TFVTH*L*GIARSLCVCHKV
DFLIG*RSQK*WFALMEIATAVSLPAFYFFFCF
FSARGISTISSAQRCLLFILNIFKKCRILCDCFF
ASQLCCEFYKNLFSFLIIYCTKAVFIAHRCL*P
IM*QFCTLTQGVTRPFLNVS*KLWLYYCLNKTG
TVVESIANTFTAICVLNIVD*HLIQDYNICYILS
VFRLLKVKGHWIQKLWNQQLILVFLINLLVNLK
ARP*LHQQVQSMSASKAELSCVT*ADRLVFNRC
LVLRLRCLNVTQSGSC*ICVPILN*PILGCDTFE
RLNWENEDK*FTCPGSKEA*KRSSNLPLPITCL
R*LSRTPRFILLVNSMWLTRSIFFLNKSRFLYV
NSEKRKAKHYVNVNGNLEILVFINYKNFLLFIRK
SIFIL*LTVKPVDDFFELGSS*RFTVNKRISS*
V*QYQKEFSSYCCLGI*G*DIIWVRSFFFSVLV
ATS*QAPKN*SSF*TDIYVKKIIKSNASAYCVML
QSSFVCFTTQFGYRTSVHCKHKQHGKG*IPVFR
L*DLVRTCCVYCNVK*KKNPPLYYSHAVLCMIN
S*IIC

Frame 2

ERGAGARG*DSPEEAARAPRHRPG*SAVARS*V
VTTVSDSWA*AVFPPQPPQ*LGLQCYSFAAGLF
PPFPHPIRMI*DLKEDDAYRRRDFSMQTFICSA
CTVIFIPCCWPSDGWTDAPFTSVQ*PSPAKHK*P
TGFCLIIF*PDSATSN*PGDA*YCHVTEADAPN
LP*PSNCSPEKTFC*LDQNIQAY**GLLCKKEA
KTPTGPGRRF*S*EGTEGLQ*WL****L*LYCKK
RRKVDGSLRN*LLDRQRFLWTGCKGI*SCGARM
GCH*NNKEQEGFSESSTDRSATS*AHEQT*H*N
EILHSAFETPLYVSKPSLFSF*NAVLQPL*LAEK
HQFPRGLFEPNTKVCATDVHCTAFPCDSRT*YH
SL*SKT*KYPSL*PQTQCNQDS*LWQFLSVGAE
DIPVYSESLLSVSRGATGNAL*PCH*YVVPRVYF
G*NAHWRTSVQWCQ*GRSDE*NSGSSGYSTCSY
S*PSTKSKKVL*EVARWHLELKEDQRWKTGVQT
TRNP*TS*HSWSGNRRTWWATCWGVRSYGR*LLE
VQRPHFKDA*L*PQNSNSTLLCSAAQFLQENS*
*RYKYK**CIYKPRHGAVSVFGHHLQYIVKLRW
LIGDKQQWESPVGSDAPASAQWWALHSCRAGHGL
RDTQSPGELARGSFACVTCHSQ
VEQHWMPGAFR
MTVSFTLEVHDVPV*GNVRQQFPAPLGWSGTEA
PTQVTVETHPVQETTFHVAPQQNALHHHHGNSSH
HHHHHHHHHHHHGQQALGNRTRPRVYNSPTNSS
STQDSMEVGHSHHSMTSLSSSTTSSSTSSSSTG
NQGNQAYQNRPVAANTLDFGQNGAMDVNLTVYSN
PRQETGIAGHPTYQFSANTGPAHYMTEGHLTMR
QGADREESPMTGVCVQQSPVASS*LH*NLSLFL
VCFYRSGVFFPKTKCKAA*IRRRLTH*TATRGQS
*FFF*LEKIAKGH*SV*KSHVQTHLHG*LRGIL
FLLPHFNLPHPSHSGVFLSFYSAKVNIQMLVLV
ICQLILK*KALHIICIKGPMRVFFFFLFVPPIPL
FFCFVLFCFGWEGGKFGFLSPLNTLGHGNAVL*
GRGTSSFHKHHLQLYERDGCGEVCQAQ*AC*VA
GIRTLLSEPTEEQSSNYMGSCGSPVAEATGR*DG
T*LVS*PRCTEKQSTGRSWPVLGRSEWWSLG*P
LALWIWTRN*KSLPFQMQSLLDMLLQTVLNAEN
TENG*FKRPFF*NRLL*PTNCKVLQGHFACVIKL
TSLLVEGHRSSGLL*WK*LQLCPFLLFTFSFAF
SRHVVSPPFLLHKDVFCSS*TFLKNAEFYVTAF
LPHNYAVNFTKIYFLF**FIVPKLFL*HIDVCNQ
*CSSSAL*HKV*LDHF*MSVENYGCTIA*TKLE
LLLNP*PIHLQQSVY*T**IDI*FKITTSVTF*
VCSGF*R*RDTGSRSYGTSS*FLYS*LTYL*T*K
QDLDCTNRSRV*VQAKQNSHA*PEQTGWYLTGA
SC*DYAALM*HSLAVAKFVFPF*IDQFWGVTLL
SG*IGRMKISNLPVQDQKKPRKEAVIYLCR*PV*
DDSAEHRVSFYWSIPCG*LGQFFF*TKAGFYM*
TVRKERLNTM*M*METWKYSFL*TTKTFCCLSG
NPYLFCN*LSSLWMIFLNLVVHKGLQ*IKGYHLE
YSNIKRNSVVTAV*EYKVKISYGSGHFFFLCWL
PHLSKHQKTKAVFKPIFT*RKS*NPMLLHTVLC
YSPVLCALLHSLVTGLLCIVNINSMEKVKYLCSD
CKI*SGLAVYIVTLNEKRTPLCIIVMRSYV**T
VE*FV

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