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Sequences

Sequence NM_001282

GTCAGAGTTTCCTGCCCACCATCTTTGTCCCTGGCAAAGTGGGTTTTGCGCAGTGGCTTAGACCTAGAAAAGAATCGTGACGGGCAGGAAACCATTACAC CACCACCTGGGCTGTGCTCTCCGGCTCCCGCCGCCACCCCCGCCCTCGCCTTCGCCTCCGCCTCCGGTGCACATTAAAGATCCAAAGTCATGACTGACTC CAAGTATTTCACAACCAATAAAAAAGGAGAAATATTTGAACTAAAAGCTGAACTCAACAATGAAAAGAAAGAAAAGAGAAAGGAGGCTGTGAAGAAAGTG ATTGCTGCTATGACCGTGGGGAAGGATGTTAGTTCTCTCTTTCCAGACGTAGTGAACTGTATGCAGACTGACAATCTGGAACTAAAGAAGCTTGTGTATC TCTACTTGATGAACTACGCCAAGAGTCAGCCAGACATGGCCATCATGGCTGTAAACAGCTTTGTGAAGGACTGTGAAGATCCTAATCCTTTGATTCGAGC CTTGGCAGTCAGAACCATGGGGTGCATCCGGGTAGACAAAATTACAGAATATCTCTGTGAGCCGCTCCGCAAGTGCTTGAAGGATGAGGATCCCTATGTT CGGAAAACAGCAGCAGTCTGCGTGGCAAAACTCCATGATATCAATGCCCAAATGGTGGAAGATCAGGGATTTCTGGATTCTCTACGGGATCTCATAGCAG ATTCAAATCCAATGGTGGTGGCTAATGCCGTAGCGGCATTATCTGAAATCAGTGAGTCTCACCCAAACAGCAACTTACTTGATCTGAACCCACAGAACAT TAATAAGCTGCTGACAGCCCTGAATGAATGCACTGAATGGGGCCAGATTTTCATCCTGGACTGCCTGTCTAATTACAACCCTAAAGATGATCGGGAGGCT CAGAGCATCTGTGAGCGGGTAACTCCCCGGCTATCCCATGCCAACTCAGCAGTGGTGCTTTCAGCGGTAAAAGTCCTAATGAAGTTTCTAGAATTGTTAC CTAAGGATTCTGACTACTACAATATGCTGCTGAAGAAGTTAGCCCCTCCACTTGTCACTTTGCTGTCTGGGGAGCCAGAAGTGCAGTATGTCGCCCTGAG GAACATCAACTTAATTGTCCAGAAAAGGCCTGAAATCTTGAAGCAGGAAATCAAAGTCTTCTTTGTGAAGTACAATGATCCCATCTATGTTAAACTAGAG AAGTTGGACATCATGATTCGTTTGGCATCTCAAGCCAACATTGCTCAGGTTCTGGCAGAACTGAAAGAATATGCTACAGAGGTGGATGTTGACTTTGTTC GAAAAGCTGTGCGGGCCATTGGACGGTGTGCCATCAAGGTGGAGCAATCTGCAGAGCGCTGTGTAAGCACATTGCTTGATCTAATCCAGACCAAAGTGAA TTATGTGGTCCAAGAAGCAATTGTTGTCATCAGGGACATCTTCCGCAAATACCCCAACAAGTATGAAAGTATCATCGCCACTCTGTGTGAGAACTTAGAC TCGCTGGATGAGCCAGATGCTCGAGCAGCTATGATTTGGATTGTGGGAGAATATGCTGAAAGAATTGACAATGCAGATGAGTTACTAGAAAGCTTCCTGG AGGGTTTTCACGATGAAAGCACCCAGGTGCAGCTCACTCTGCTTACTGCCATAGTGAAGCTGTTTCTCAAGAAACCATCAGAAACACAGGAGCTAGTCCA GCAGGTCTTGAGTTTGGCAACACAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCT AAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGG CCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGA CAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGT CCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGGTGGGACAATCCTTCATCCCAT CATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACC TGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTAT ATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGG CCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCA GGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTC CTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACA ACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACG TATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC TAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACA CTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACT GCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTC TTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCA CTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGG CAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTT CCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATAATCTCATTTGATTGCTCTGCAGTTGGGAACGGTGATCTTCTT GAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAGTTATACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAA TCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGCTGTCCCCTCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAA AATTCTACTTTTAGAGTTGAAACAGAGTAATAACTTATCTAACCCTCTTTTCCTACAAAGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCGT CAGCTGTGTAGTGGCAAAGCCGAGACCGAGTCTCCTAAGTCCCCGTCAGTGTGGTTTTCACCACAGGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCT CCTGCCTTTTCTGTGCCTAGTTTTTGGCTCTTCACATATTCCATATTGATTTTGACGCTCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAAT TACTCGAAGGTAAAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCCCCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAG ATGAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGCTCTTTCTTCATGATACTTAGTCTGCAGGGCATATTAAGATCA TCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTTCCCCCTACCCCACTTAATGCGTTGGATATGATTTTTCAAAGA ATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGGCACTTGTTGCATTGCCTGGCACCCAATATTCAGGGTCCATGA CTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGGCGTCATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAG GAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTGAAATAACCCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCA CAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAATATTTGGGGAAGGAGGGAGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCA GTAGGAAACAGCATAGGATTGTATGTGGGAGGTGGATAGGTCGGTGATGTGTGGAGCGGAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCT GGAGTCAGTGGATACAAGTAGTGCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTCAAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAA GCAGACAACACAATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTCTCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAG CTGACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATCACACCCCTGAGCAGAGTTAGGGAGGAATTCTACTTCCCATAA AAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTCATTCCAAGCTTGGCCAAATTGGGGAAGTGGGATGGAGGTTGC CCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACAAAGAGCAGGAGAAGCAAACACCCAGAACTCTTTTGCTGGTCA GAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCTTGAGACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATG TTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTCGGGAGGGTGGGGGTTGGGGGAAGCTTGACCTTGTGTCTTCGTCAATAAA CTCACATTTACACAAAATGAA

refseq_AP2B1.F1 (forward primer)
refseq_AP2B1.R1 (reverse primer)
Single exon skipping

Frame 0

VRVSCPPSLSLAKWVLRSGLDLEKNRDGQETIT PPPGLCSPAPAATPALAFASASGAH*RSKVMTDS KYFTTNKKGEIFELKAELNNEKKEKRKEAVKKV IAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVY LYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRA LAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYV RKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIA DSNPMVVANAVAALSEISESHPNSNLLDLNPQNI NKLLTALNECTEWGQIFILDCLSNYNPKDDREA QSICERVTPRLSHANSAVVLSAVKVLMKFLELL PKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALR NINLIVQKRPEILKQEIKVFFVKYNDPIYVKLE KLDIMIRLASQANIAQVLAELKEYATEVDVDFV RKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVN YVVQEAIVVIRDIFRKYPNKYESIIATLCENLD SLDEPDARAAMIWIVGEYAERIDNADELLESFL EGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQ QVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTA KEVVLSEKPLISEETDLIEPTLLDELICHIGSL ASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGD SPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLG PPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIP SSVPATFAPSPTPAVVSSGLNDLFELSTGIGMAP GGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIY MEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPL AIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQ VAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVF LATWKDIPNENELQFQIKECHLNADTVSSKLQN NNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELR IQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN *QDWSSTLQPCCDRCKSRTLNWKKLYCCVESEH TEAT*QGSN*SNLC*H*GTTCWIVLASCEHL*PL LQSPPTSCHLLLLSVLTCGLLHAVPMAGFFYTL F*V*FGIL*LRAHFKSRKRQQILKQGKV*LKHC TLLFYTFVHMRNQGISATSRKH*NDCH*PHSPGG RDAVTYPSF*WVLLPVVALSLVIWIFSLLFSFF PLQTPFPWPSLHASPFPYYNLI*LLCSWER*SS *MMFQCAKTIEPVSTKADRSYTLLLSFPLNKPAN PTNSGI*VEMGNKNPDAVPSPPLLYFSGPVQI* NSTFRVETE**LI*PSFPTKEKDKRHKGYRQGP SAV*WQSRDRVS*VPVSVVFTTGLSLVVFP*CLL LPFLCLVFGSSHIPY*F*RSVYWHQVAAEYLLN YSKVKPDARMKV*PVFPICPWSPTY*GQQNRCR DEVSLEMLQMLFIPSAL*SALSS*YLVCRAY*DH PRGSGSSCHL*KDWGI*NLPPTPLNALDMIFQR MLHAQNTSLFSSVTLFDLRALVALPGTQYSGSM TKTGLLRCPA*IRGTSGSTGVMLD*DLTHWTQRR NRGKQEQNYPTPLFHV*NNPVSYQLQSLWGAVP QSTFLNLENLQEKNIWGRREEICPLHTTPEAHG SRKQHRIVCGRWIGR*CVERKSRLVKFPSWDLFL ESVDTSSAEGSHCK*CSHLKANYHSRRKSVSGQ ADNTISYQNMSLNPRNKASLSLPTSDG*QLLFS ADLTEPTHELFTPWGSHLPSHP*AELGRNSTSHK RTSPERQNLLPPPRLPSWLIPSLAKLGKWDGGC PASPLLCLSVSL*CQLASYKEQEKQTPRTLLLV RDSLSVCPHPSLLCVCVVKLETLERNGEGGQGKC CPKNASHSSVLIGSCFSGGWGLGEA*PCVFVNK LTFTQNE

Frame 1

SEFPAHHLCPWQSGFCAVA*T*KRIVTGRKPLH HHLGCALRLPPPPPPSPSPPPPVHIKDPKS*LT PSISQPIKKEKYLN*KLNSTMKRKKRERRL*RK* LLL*PWGRMLVLSFQT**TVCRLTIWN*RSLCI ST**TTPRVSQTWPSWL*TAL*RTVKILIL*FE PWQSEPWGASG*TKLQNISVSRSASA*RMRIPMF GKQQQSAWQNSMISMPKWWKIRDFWILYGIS*Q IQIQWWWLMP*RHYLKSVSLTQTATYLI*THRT LISC*QP*MNALNGARFSSWTACLITTLKMIGRL RASVSG*LPGYPMPTQQWCFQR*KS**SF*NCY LRILTTTICC*RS*PLHLSLCCLGSQKCSMSP* GTST*LSRKGLKS*SRKSKSSL*STMIPSMLN*R SWTS*FVWHLKPTLLRFWQN*KNMLQRWMLTLF EKLCGPLDGVPSRWSNLQSAV*AHCLI*SRPK* IMWSKKQLLSSGTSSANTPTSMKVSSPLCVRT*T RWMSQMLEQL*FGLWENMLKELTMQMSY*KASW RVFTMKAPRCSSLCLLP**SCFSRNHQKHRS*S SRS*VWQHRILIILTFETGAIFIGAFSQLTLLQL KK*SCLRSH*SLRRRTLLSQLCWMS*SATLVLW PLCIISLPMLLWKEVMEFIVNTCQFIMGALMQV TALLALPLQRTWNSLRLSPLKVIF*GIF*TLTSV PQSMCHRCPPCRWEQWIS*EED*IVWWDNPSSH HRCLQPLLLHLHLLWSAVD*MTCLNSPQG*AWH LVDMWLLRLSGYLQ*RLKAWRFPEHLLTAKGTSI WK*TSPIKLCST*QILQSSLTKIALVSSPALLW PSIHH*CQTRALMSPCLSIPWAQS*RWNL*ITS RWL*KTISMSSTSAASSHSMCFL*KMAKWSARSS LQHGRIFPMKMNFSFRLRNVI*MLTLFPASCKT TMFILLPRGMWKGRTCCTNP*SSLMAFGFWPNY VSSQETPITRCH*SVELLKSLNTSIRSTTAF*KT NKTGPVPFNHAVIGASQELLTGRNCIAA*NLNT LRPPSKVVTSLTCANIRAQPVG*F*LPVNICNH CFSHLPPLATCCCYLSLLVGFSMLCQWLAFSTPS FECSLVFCN*ELISKAEKDNKY*SKEKCN*NTA LYCFILLYI*EIKGLVQPVESIEMTVINHTVLE AEMQLPTLAFDGFSYL**PYPWSFGFSVCFFLFF PSKLLFLGQAFMLPPFHIIISFDCSAVGNGDLL E*CFSVQKL*SLSAPKLTEVIPYSFPFP*TNLL IPLIQEFE*RWGTRTQMLSPHPLSCISQVQFKSK ILLLELKQSNNLSNPLFLQRRKIKGTKVTAKAR QLCSGKAETESPKSPSVWFSPQDCLLSFSPNAF SCLFCA*FLALHIFHIDFDALYIGIRWQLNIF*I TRR*SQMPE*RCSQCFPYAPGAPLIEASRIGAE MK*A*RCCKCSLSLQLSDLLFLHDT*SAGHIKI IPEVQAVPVISEKTGGYEIFPLPHLMRWI*FFKE CFMPKIPACLAVLHCLICGHLLHCLAPNIQGP* LRLVFSDALLKSGALQAPQASCWTET*LTGLRG GIVENKSKTTPHPYFMSEITLFHTSCKACGERSH KALS*TLRISKRKIFGEGGRKYVPCTPPLKHMA VGNSIGLYVGGG*VGDVWSGKAGW*SSLLGTYS WSQWIQVVQKVHTANSVLISKQTIIPEGKVCQGK QTTQFPIRICPSTPETRLLSASPPVMDNSSYSQ LT*LSQPMNSSLLGEATSHHTPEQS*GGILLPI KGPLLRGKTCCLHHGFPLGSFQAWPNWGSGMEVA LHPPSSA*VCLCNVSWHHTKSRRSKHPELFCWS EIP*VSVLTQACSVSVL*SLRLWKEMGRGGRGN VALRMLLIPLFLLGPVFREGGGWGKLDLVSSSIN SHLHKM

Frame 2

QSFLPTIFVPGKVGFAQWLRPRKES*RAGNHYT TTWAVLSGSRRHPRPRLRLRLRCTLKIQSHD*L QVFHNQ*KRRNI*TKS*TQQ*KERKEKGGCEES DCCYDRGEGC*FSLSRRSELYAD*QSGTKEACVS LLDELRQESARHGHHGCKQLCEGL*RS*SFDSS LGSQNHGVHPGRQNYRISL*AAPQVLEG*GSLC SENSSSLRGKTP*YQCPNGGRSGISGFSTGSHSR FKSNGGG*CRSGII*NQ*VSPKQQLT*SEPTEH **AADSPE*MH*MGPDFHPGLPV*LQP*R*SGG SEHL*AGNSPAIPCQLSSGAFSGKSPNEVSRIVT *GF*LLQYAAEEVSPSTCHFAVWGARSAVCRPE EHQLNCPEKA*NLEAGNQSLLCEVQ*SHLC*TR EVGHHDSFGISSQHCSGSGRTERICYRGGC*LCS KSCAGHWTVCHQGGAICRALCKHIA*SNPDQSE LCGPRSNCCHQGHLPQIPQQV*KYHRHSV*ELR LAG*ARCSSSYDLDCGRIC*KN*QCR*VTRKLPG GFSR*KHPGAAHSAYCHSEAVSQETIRNTGASP AGLEFGNTGF**S*PSRPGLYLLAPSLN*PCYS *RSSLV*EATDL*GDGPY*ANSAG*ANLPHWFFG LCVS*ASQCFCGRKSWNSS*TLANSSWEH*CR* QPCWHYHCNEPGTASGYPLSR*SSRGSFKP*PR SPSQCATGVLHADGSSGSPRRRTR*SGGTILHPI IGACNLCSFTYTCCGQQWTE*PV*TLHRDRHGT WWICGS*GCLATCSKG*RLGDFRNIYSPPRAHL YGNELHQ*SSAAHDRFCNPV*QK*LWCHPQHSSG HPYTTDAKPEH*CLPASQYLGPSHEDGTSE*PP GGCEKQYRCLLLQLPHPTQCAFCRRWQNGAPGL PCNMEGYSQ*K*TSVSD*GMSFKC*HCFQQVAKQ QCLYYCQEECGRAGHAVPIPEAH*WHLDFGRTT YPARKPQLHAVTEV*SS*SLSIHLSGLRQHFEK LTRLVQYPSTML*SVQVKNS*LEEIVLLRRI*TH *GHLAR**LV*PVLTLGHNLLDSFSFL*TFVTT ASVTSHLLPPAAAICPYLWASPCCANGWLFLHP LLSVVWYFVIESSFQKQKKTTNIKARKSVTETLH FTVLYFCTYEKSRD*CNQ*KALK*LSLTTQSWR QRCSYLP*LLMGSLTCSSLIPGHLDFQFAFFFF SPPNSFSLAKPSCFPLSIL*SHLIALQLGTVIFL NDVSVCKNYRACQHQS*QKLYLTPFLSPEQTC* SH*FRNLSRDGEQEPRCCPLTPSPVFLRSSSNL KFYF*S*NRVITYLTLFSYKGER*KAQRLPPRPV SCVVAKPRPSLLSPRQCGFHHRTVSCRFPLMPS PAFSVPSFWLFTYSILILTLCILASGGS*ISFE LLEGKARCQNEGVASVSHMPLEPHLLRPAE*VQR *SELRDVANALYPFSSLICSFFMILSLQGILRS SQRFRQFLSSLKRLGDMKSSPYPT*CVGYDFSK NASCPKYQPV*QCYTV*SAGTCCIAWHPIFRVHD *DWSSQMPCLNQGHFRLHRRHVGLRPNSLDSEE ESWKTRAKLPHTPISCLK*PCFIPVAKLVGSGP TKHFLKP*ESPREKYLGKEGGNMSLAHHP*STWQ *ETA*DCMWEVDRSVMCGAEKQVGKVPFLGLIP GVSGYK*CRRFTLQIVFSSQSKLSFQKEKCVRA SRQHNFLSEYVPQPPKQGFSQPPHQ*WITAPILS *PD*ANP*TLHSLGKPPPITPLSRVREEFYFP* KDLS*EAKPVASTTASLLAHSKLGQIGEVGWRL PCIPPPLPECVFVMSAGIIQRAGEANTQNSFAGQ RFPECLSSPKPALCLCCEA*DSGKKWGGGAGEM LP*ECFSFLCSYWVLFFGRVGVGGSLTLCLRQ* THIYTK*

Sequence NM_001030006

GTCAGAGTTTCCTGCCCACCATCTTTGTCCCTGGCAAAGTGGGTTTTGCGCAGTGGCTTAGACCTAGAAAAGAATCGTGACGGGCAGGAAACCATTACAC CACCACCTGGGCTGTGCTCTCCGGCTCCCGCCGCCACCCCCGCCCTCGCCTTCGCCTCCGCCTCCGGTGCACATTAAAGATCCAAAGTCATGACTGACTC CAAGTATTTCACAACCAATAAAAAAGGAGAAATATTTGAACTAAAAGCTGAACTCAACAATGAAAAGAAAGAAAAGAGAAAGGAGGCTGTGAAGAAAGTG ATTGCTGCTATGACCGTGGGGAAGGATGTTAGTTCTCTCTTTCCAGACGTAGTGAACTGTATGCAGACTGACAATCTGGAACTAAAGAAGCTTGTGTATC TCTACTTGATGAACTACGCCAAGAGTCAGCCAGACATGGCCATCATGGCTGTAAACAGCTTTGTGAAGGACTGTGAAGATCCTAATCCTTTGATTCGAGC CTTGGCAGTCAGAACCATGGGGTGCATCCGGGTAGACAAAATTACAGAATATCTCTGTGAGCCGCTCCGCAAGTGCTTGAAGGATGAGGATCCCTATGTT CGGAAAACAGCAGCAGTCTGCGTGGCAAAACTCCATGATATCAATGCCCAAATGGTGGAAGATCAGGGATTTCTGGATTCTCTACGGGATCTCATAGCAG ATTCAAATCCAATGGTGGTGGCTAATGCCGTAGCGGCATTATCTGAAATCAGTGAGTCTCACCCAAACAGCAACTTACTTGATCTGAACCCACAGAACAT TAATAAGCTGCTGACAGCCCTGAATGAATGCACTGAATGGGGCCAGATTTTCATCCTGGACTGCCTGTCTAATTACAACCCTAAAGATGATCGGGAGGCT CAGAGCATCTGTGAGCGGGTAACTCCCCGGCTATCCCATGCCAACTCAGCAGTGGTGCTTTCAGCGGTAAAAGTCCTAATGAAGTTTCTAGAATTGTTAC CTAAGGATTCTGACTACTACAATATGCTGCTGAAGAAGTTAGCCCCTCCACTTGTCACTTTGCTGTCTGGGGAGCCAGAAGTGCAGTATGTCGCCCTGAG GAACATCAACTTAATTGTCCAGAAAAGGCCTGAAATCTTGAAGCAGGAAATCAAAGTCTTCTTTGTGAAGTACAATGATCCCATCTATGTTAAACTAGAG AAGTTGGACATCATGATTCGTTTGGCATCTCAAGCCAACATTGCTCAGGTTCTGGCAGAACTGAAAGAATATGCTACAGAGGTGGATGTTGACTTTGTTC GAAAAGCTGTGCGGGCCATTGGACGGTGTGCCATCAAGGTGGAGCAATCTGCAGAGCGCTGTGTAAGCACATTGCTTGATCTAATCCAGACCAAAGTGAA TTATGTGGTCCAAGAAGCAATTGTTGTCATCAGGGACATCTTCCGCAAATACCCCAACAAGTATGAAAGTATCATCGCCACTCTGTGTGAGAACTTAGAC TCGCTGGATGAGCCAGATGCTCGAGCAGCTATGATTTGGATTGTGGGAGAATATGCTGAAAGAATTGACAATGCAGATGAGTTACTAGAAAGCTTCCTGG AGGGTTTTCACGATGAAAGCACCCAGGTGCAGCTCACTCTGCTTACTGCCATAGTGAAGCTGTTTCTCAAGAAACCATCAGAAACACAGGAGCTAGTCCA GCAGGTCTTGAGTTTGGCAACACAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCT AAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGG CCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGA CAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGT CCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGG GCATTGGAGGAAGTCCGGCAGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACT GAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTG GAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGT TTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATAC CTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAAT GTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAAT GTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATC CCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTC TCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTC TTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAAC CTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGG CTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGAC AACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAG AAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTA TCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATA ATCTCATTTGATTGCTCTGCAGTTGGGAACGGTGATCTTCTTGAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAG TTATACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAATCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGCTGTCCCC TCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAAAATTCTACTTTTAGAGTTGAAACAGAGTAATAACTTATCTAACCCTCTTTTCCTACAA AGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCGTCAGCTGTGTAGTGGCAAAGCCGAGACCGAGTCTCCTAAGTCCCCGTCAGTGTGGTTTT CACCACAGGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCTCCTGCCTTTTCTGTGCCTAGTTTTTGGCTCTTCACATATTCCATATTGATTTTGACGC TCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAATTACTCGAAGGTAAAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCC CCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAGATGAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGC TCTTTCTTCATGATACTTAGTCTGCAGGGCATATTAAGATCATCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTT CCCCCTACCCCACTTAATGCGTTGGATATGATTTTTCAAAGAATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGG CACTTGTTGCATTGCCTGGCACCCAATATTCAGGGTCCATGACTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGG CGTCATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAGGAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTGAAATAAC CCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCACAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAATATTTGGGGAAGGAGGG AGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCAGTAGGAAACAGCATAGGATTGTATGTGGGAGGTGGATAGGTCGGTGATGTGTGGAGCG GAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCTGGAGTCAGTGGATACAAGTAGTGCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTC AAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAAGCAGACAACACAATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTC TCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAGCTGACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATC ACACCCCTGAGCAGAGTTAGGGAGGAATTCTACTTCCCATAAAAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTC ATTCCAAGCTTGGCCAAATTGGGGAAGTGGGATGGAGGTTGCCCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACA AAGAGCAGGAGAAGCAAACACCCAGAACTCTTTTGCTGGTCAGAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCT TGAGACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATGTTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTCGGGAGGG TGGGGGTTGGGGGAAGCTTGACCTTGTGTCTTCGTCAATAAACTCACATTTACACAAAATGAA

refseq_AP2B1.F1 (forward primer)
refseq_AP2B1.R1 (reverse primer)
Single exon skipping

Frame 0

VRVSCPPSLSLAKWVLRSGLDLEKNRDGQETIT PPPGLCSPAPAATPALAFASASGAH*RSKVMTDS KYFTTNKKGEIFELKAELNNEKKEKRKEAVKKV IAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVY LYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRA LAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYV RKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIA DSNPMVVANAVAALSEISESHPNSNLLDLNPQNI NKLLTALNECTEWGQIFILDCLSNYNPKDDREA QSICERVTPRLSHANSAVVLSAVKVLMKFLELL PKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALR NINLIVQKRPEILKQEIKVFFVKYNDPIYVKLE KLDIMIRLASQANIAQVLAELKEYATEVDVDFV RKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVN YVVQEAIVVIRDIFRKYPNKYESIIATLCENLD SLDEPDARAAMIWIVGEYAERIDNADELLESFL EGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQ QVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTA KEVVLSEKPLISEETDLIEPTLLDELICHIGSL ASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGD SPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLG PPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGG GIGGSPAVGQSFIPSSVPATFAPSPTPAVVSSGL NDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGL EISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQ FNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNT LGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLN VLFVEDGKMERQVFLATWKDIPNENELQFQIKE CHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQS LKLTNGIWILAELRIQPGNPNYTLSLKCRAPEV SQYIYQVYDSILKN*QDWSSTLQPCCDRCKSRT LNWKKLYCCVESEHTEAT*QGSN*SNLC*H*GTT CWIVLASCEHL*PLLQSPPTSCHLLLLSVLTCG LLHAVPMAGFFYTLF*V*FGIL*LRAHFKSRKR QQILKQGKV*LKHCTLLFYTFVHMRNQGISATSR KH*NDCH*PHSPGGRDAVTYPSF*WVLLPVVAL SLVIWIFSLLFSFFPLQTPFPWPSLHASPFPYY NLI*LLCSWER*SS*MMFQCAKTIEPVSTKADRS YTLLLSFPLNKPANPTNSGI*VEMGNKNPDAVP SPPLLYFSGPVQI*NSTFRVETE**LI*PSFPT KEKDKRHKGYRQGPSAV*WQSRDRVS*VPVSVVF TTGLSLVVFP*CLLLPFLCLVFGSSHIPY*F*R SVYWHQVAAEYLLNYSKVKPDARMKV*PVFPIC PWSPTY*GQQNRCRDEVSLEMLQMLFIPSAL*SA LSS*YLVCRAY*DHPRGSGSSCHL*KDWGI*NL PPTPLNALDMIFQRMLHAQNTSLFSSVTLFDLR ALVALPGTQYSGSMTKTGLLRCPA*IRGTSGSTG VMLD*DLTHWTQRRNRGKQEQNYPTPLFHV*NN PVSYQLQSLWGAVPQSTFLNLENLQEKNIWGRR EEICPLHTTPEAHGSRKQHRIVCGRWIGR*CVER KSRLVKFPSWDLFLESVDTSSAEGSHCK*CSHL KANYHSRRKSVSGQADNTISYQNMSLNPRNKAS LSLPTSDG*QLLFSADLTEPTHELFTPWGSHLPS HP*AELGRNSTSHKRTSPERQNLLPPPRLPSWL IPSLAKLGKWDGGCPASPLLCLSVSL*CQLASY KEQEKQTPRTLLLVRDSLSVCPHPSLLCVCVVKL ETLERNGEGGQGKCCPKNASHSSVLIGSCFSGG WGLGEA*PCVFVNKLTFTQNE

Frame 1

SEFPAHHLCPWQSGFCAVA*T*KRIVTGRKPLH HHLGCALRLPPPPPPSPSPPPPVHIKDPKS*LT PSISQPIKKEKYLN*KLNSTMKRKKRERRL*RK* LLL*PWGRMLVLSFQT**TVCRLTIWN*RSLCI ST**TTPRVSQTWPSWL*TAL*RTVKILIL*FE PWQSEPWGASG*TKLQNISVSRSASA*RMRIPMF GKQQQSAWQNSMISMPKWWKIRDFWILYGIS*Q IQIQWWWLMP*RHYLKSVSLTQTATYLI*THRT LISC*QP*MNALNGARFSSWTACLITTLKMIGRL RASVSG*LPGYPMPTQQWCFQR*KS**SF*NCY LRILTTTICC*RS*PLHLSLCCLGSQKCSMSP* GTST*LSRKGLKS*SRKSKSSL*STMIPSMLN*R SWTS*FVWHLKPTLLRFWQN*KNMLQRWMLTLF EKLCGPLDGVPSRWSNLQSAV*AHCLI*SRPK* IMWSKKQLLSSGTSSANTPTSMKVSSPLCVRT*T RWMSQMLEQL*FGLWENMLKELTMQMSY*KASW RVFTMKAPRCSSLCLLP**SCFSRNHQKHRS*S SRS*VWQHRILIILTFETGAIFIGAFSQLTLLQL KK*SCLRSH*SLRRRTLLSQLCWMS*SATLVLW PLCIISLPMLLWKEVMEFIVNTCQFIMGALMQV TALLALPLQRTWNSLRLSPLKVIF*GIF*TLTSV PQSMCHRCPPCRWEQWIS*EED*IVCLAVTLAG ALEEVRQWDNPSSHHRCLQPLLLHLHLLWSAVD *MTCLNSPQG*AWHLVDMWLLRLSGYLQ*RLKAW RFPEHLLTAKGTSIWK*TSPIKLCST*QILQSS LTKIALVSSPALLWPSIHH*CQTRALMSPCLSI PWAQS*RWNL*ITSRWL*KTISMSSTSAASSHSM CFL*KMAKWSARSSLQHGRIFPMKMNFSFRLRN VI*MLTLFPASCKTTMFILLPRGMWKGRTCCTN P*SSLMAFGFWPNYVSSQETPITRCH*SVELLKS LNTSIRSTTAF*KTNKTGPVPFNHAVIGASQEL LTGRNCIAA*NLNTLRPPSKVVTSLTCANIRAQ PVG*F*LPVNICNHCFSHLPPLATCCCYLSLLVG FSMLCQWLAFSTPSFECSLVFCN*ELISKAEKD NKY*SKEKCN*NTALYCFILLYI*EIKGLVQPV ESIEMTVINHTVLEAEMQLPTLAFDGFSYL**PY PWSFGFSVCFFLFFPSKLLFLGQAFMLPPFHII ISFDCSAVGNGDLLE*CFSVQKL*SLSAPKLTE VIPYSFPFP*TNLLIPLIQEFE*RWGTRTQMLSP HPLSCISQVQFKSKILLLELKQSNNLSNPLFLQ RRKIKGTKVTAKARQLCSGKAETESPKSPSVWF SPQDCLLSFSPNAFSCLFCA*FLALHIFHIDFDA LYIGIRWQLNIF*ITRR*SQMPE*RCSQCFPYA PGAPLIEASRIGAEMK*A*RCCKCSLSLQLSDL LFLHDT*SAGHIKIIPEVQAVPVISEKTGGYEIF PLPHLMRWI*FFKECFMPKIPACLAVLHCLICG HLLHCLAPNIQGP*LRLVFSDALLKSGALQAPQ ASCWTET*LTGLRGGIVENKSKTTPHPYFMSEIT LFHTSCKACGERSHKALS*TLRISKRKIFGEGG RKYVPCTPPLKHMAVGNSIGLYVGGG*VGDVWS GKAGW*SSLLGTYSWSQWIQVVQKVHTANSVLIS KQTIIPEGKVCQGKQTTQFPIRICPSTPETRLL SASPPVMDNSSYSQLT*LSQPMNSSLLGEATSH HTPEQS*GGILLPIKGPLLRGKTCCLHHGFPLGS FQAWPNWGSGMEVALHPPSSA*VCLCNVSWHHT KSRRSKHPELFCWSEIP*VSVLTQACSVSVL*S LRLWKEMGRGGRGNVALRMLLIPLFLLGPVFREG GGWGKLDLVSSSINSHLHKM

Frame 2

QSFLPTIFVPGKVGFAQWLRPRKES*RAGNHYT TTWAVLSGSRRHPRPRLRLRLRCTLKIQSHD*L QVFHNQ*KRRNI*TKS*TQQ*KERKEKGGCEES DCCYDRGEGC*FSLSRRSELYAD*QSGTKEACVS LLDELRQESARHGHHGCKQLCEGL*RS*SFDSS LGSQNHGVHPGRQNYRISL*AAPQVLEG*GSLC SENSSSLRGKTP*YQCPNGGRSGISGFSTGSHSR FKSNGGG*CRSGII*NQ*VSPKQQLT*SEPTEH **AADSPE*MH*MGPDFHPGLPV*LQP*R*SGG SEHL*AGNSPAIPCQLSSGAFSGKSPNEVSRIVT *GF*LLQYAAEEVSPSTCHFAVWGARSAVCRPE EHQLNCPEKA*NLEAGNQSLLCEVQ*SHLC*TR EVGHHDSFGISSQHCSGSGRTERICYRGGC*LCS KSCAGHWTVCHQGGAICRALCKHIA*SNPDQSE LCGPRSNCCHQGHLPQIPQQV*KYHRHSV*ELR LAG*ARCSSSYDLDCGRIC*KN*QCR*VTRKLPG GFSR*KHPGAAHSAYCHSEAVSQETIRNTGASP AGLEFGNTGF**S*PSRPGLYLLAPSLN*PCYS *RSSLV*EATDL*GDGPY*ANSAG*ANLPHWFFG LCVS*ASQCFCGRKSWNSS*TLANSSWEH*CR* QPCWHYHCNEPGTASGYPLSR*SSRGSFKP*PR SPSQCATGVLHADGSSGSPRRRTR*SAWQ*PWRG HWRKSGSGTILHPIIGACNLCSFTYTCCGQQWT E*PV*TLHRDRHGTWWICGS*GCLATCSKG*RL GDFRNIYSPPRAHLYGNELHQ*SSAAHDRFCNPV *QK*LWCHPQHSSGHPYTTDAKPEH*CLPASQY LGPSHEDGTSE*PPGGCEKQYRCLLLQLPHPTQ CAFCRRWQNGAPGLPCNMEGYSQ*K*TSVSD*GM SFKC*HCFQQVAKQQCLYYCQEECGRAGHAVPI PEAH*WHLDFGRTTYPARKPQLHAVTEV*SS*S LSIHLSGLRQHFEKLTRLVQYPSTML*SVQVKNS *LEEIVLLRRI*TH*GHLAR**LV*PVLTLGHN LLDSFSFL*TFVTTASVTSHLLPPAAAICPYLW ASPCCANGWLFLHPLLSVVWYFVIESSFQKQKKT TNIKARKSVTETLHFTVLYFCTYEKSRD*CNQ* KALK*LSLTTQSWRQRCSYLP*LLMGSLTCSSL IPGHLDFQFAFFFFSPPNSFSLAKPSCFPLSIL* SHLIALQLGTVIFLNDVSVCKNYRACQHQS*QK LYLTPFLSPEQTC*SH*FRNLSRDGEQEPRCCP LTPSPVFLRSSSNLKFYF*S*NRVITYLTLFSYK GER*KAQRLPPRPVSCVVAKPRPSLLSPRQCGF HHRTVSCRFPLMPSPAFSVPSFWLFTYSILILT LCILASGGS*ISFELLEGKARCQNEGVASVSHMP LEPHLLRPAE*VQR*SELRDVANALYPFSSLIC SFFMILSLQGILRSSQRFRQFLSSLKRLGDMKS SPYPT*CVGYDFSKNASCPKYQPV*QCYTV*SAG TCCIAWHPIFRVHD*DWSSQMPCLNQGHFRLHR RHVGLRPNSLDSEEESWKTRAKLPHTPISCLK* PCFIPVAKLVGSGPTKHFLKP*ESPREKYLGKEG GNMSLAHHP*STWQ*ETA*DCMWEVDRSVMCGA EKQVGKVPFLGLIPGVSGYK*CRRFTLQIVFSS QSKLSFQKEKCVRASRQHNFLSEYVPQPPKQGFS QPPHQ*WITAPILS*PD*ANP*TLHSLGKPPPI TPLSRVREEFYFP*KDLS*EAKPVASTTASLLA HSKLGQIGEVGWRLPCIPPPLPECVFVMSAGIIQ RAGEANTQNSFAGQRFPECLSSPKPALCLCCEA *DSGKKWGGGAGEMLP*ECFSFLCSYWVLFFGR VGVGGSLTLCLRQ*THIYTK*