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Sequences

Sequence NM_080550

GATAAGGTGGCGGCGGCGAAGGCAGCGGCAGGTCGGGAGCAAGATGGCGCTGCGGCCAGGAGCTGGTTCTGGTGGCGGCGGGGCCGCGGGAGCTGGCGCG GGGTCCGCCGGGGGAGGCGGCTTCATGTTTCCTGTTGCAGGTGGGATAAGACCCCCTCAAGCAGGCCTGATGCCGATGCAGCAACAAGGATTTCCTATGG TCTCTGTCATGCAGCCTAATATGCAAGGCATTATGGGAATGAATTACAGCTCTCAGATGTCCCAAGGACCTATTGCTATGCAGGCAGGAATACCAATGGG ACCAATGCCAGCAGCGGGAATGCCTTACCTAGGACAAGCACCCTTCCTGGGCATGCGTCCTCCAGGCCCACAGTACACTCCAGACATGCAGAAGCAGTTT GCCGAAGAGCAGCAGAAACGATTTGAACAGCAGCAAAAACTCTTAGAAGAAGAAAGAAAAAGACGCCAGTTTGAAGAGCAGAAGCAAAAGCTCAGACTTT TGAGCAGTGTGAAACCCAAGACAGGAGAGAAGAGTAGAGATGATGCTTTGGAAGCCATAAAAGGAAATTTAGATGGGTTTTCCAGAGATGCAAAAATGCA CCCTACTCCAGCATCGCACCCCAAGAAACCAGGCCCTTCCTTGGAGGAGAAGTTCCTAGTATCTTGTGATATAAGTACATCTGGGCAGGAACAAATTAAA TTAAATACTTCTGAAGTTGGCCACAAAGCCCTAGGCCCAGGTTCCAGTAAGAAGTATCCCAGTTTAATGGCCAGTAACGGGGTTGCTGTAGATGGATGTG TAAGTGGTACCACCACTGCAGAGGCAGAAAATACTTCAGATCAAAACCTGTCAATTGAAGAGAGTGGTGTGGGAGTATTTCCCTCACAGGATCCTGCTCA GCCCAGAATGCCTCCTTGGATTTACAATGAGAGTTTGGTTCCAGATGCCTATAAGAAAATCTTAGAAACCACAATGACTCCAACTGGAATAGATACTGCC AAACTGTATCCCATTCTGATGTCATCTGGGCTTCCCAGGGAAACTCTTGGACAGATATGGGCCTTAGCTAATCGAACTACACCTGGCAAACTTACAAAAG AAGAACTTTATACCGTTCTAGCCATGATAGCGGTAACACAGAGGGGCGTTCCTGCAATGAGTCCTGATGCTTTAAACCAGTTCCCAGCAGCTCCTATTCC AACTTTAAGTGGCTTTTCTATGACTCTGCCTACACCGGTGAGTCAGCCAACTGTGATACCTTCAGGTCCTGCGGGCTCCATGCCCCTCAGCCTTGGACAG CCAGTCATGGGCATTAACCTTGTTGGACCAGTGGGTGGAGCTGCAGCCCAGGCTTCTAGTGGTTTCATACCAACCTACCCTGCAAATCAGGTAGTAAAGC CAGAAGAAGATGACTTCCAGGATTTTCAAGATGCTTCTAAGTCAGGATCCCTTGATGACTCATTCAGTGATTTCCAAGAGTTGCCTGCTTCTTCAAAAAC AAGTAACTCCCAGCATGGAAACAGTGCCCCTTCTTTGTTGATGCCACTTCCTGGAACTAAAGCATTGCCTTCAATGGACAAATATGCTGTGTTTAAAGGA ATTGCAGCTGACAAGTCCTCTGAAAATACTGTTCCACCTGGAGATCCTGGTGATAAATATAGTGCTTTCAGAGAACTTGAACAGACAGCAGAGAATAAAC CTTTAGGAGAAAGCTTTGCAGAATTCAGATCTGCAGGAACTGATGATGGTTTCACCGATTTTAAAACAGCCGATAGTGTATCACCACTAGAGCCACCAAC AAAAGACAAAACTTTTCCACCATCCTTCCCCTCAGGAACTATACAACAGAAACAACAAACACAAGTGAAAAACCCTCTGAACTTAGCAGACCTAGATATG TTTTCCTCAGTTAATTGCAGCAGCGAGAAACCATTGTCTTTTTCAGCTGTGTTTAGCACATCAAAATCAGTTTCTACACCACAGTCAACAGGTTCTGCTG CTACTATGACAGCATTGGCAGCAACAAAAACTTCTAGTTTGGCTGATGATTTTGGAGAATTCAGCCTTTTTGGGGAATATTCTGGTCTAGCACCTGTTGG GGAGCAGGATGACTTTGCAGATTTTATGGCTTTCAGTAATAGCTCTATTTCATCTGAGCAAAAGCCGGATGACAAATATGATGCCCTTAAAGAGGAAGCC AGTCCTGTTCCTCTAACCAGCAACGTGGGCAGCACAGTGAAGGGTGGACAAAACTCGACTGCTGCGTCTACCAAGTACGATGTCTTCAGACAACTTTCTC TGGAAGGGTCTGGACTAGGTGTTGAAGACCTGAAAGATAACACTCCTTCAGGAAAAAGTGATGATGATTTTGCTGACTTCCACTCCAGTAAATTTTCTTC CATAAACTCGGACAAATCCCTGGGAGAGAAAGCAGTGGCTTTCAGACACACCAAAGAAGACTCTGCATCAGTGAAGTCCTTAGATCTCCCTTCCATTGGT GGCAGCAGTGTTGGCAAGGAGGACTCTGAAGATGCACTCTCTGTTCAGTTTGACATGAAATTGGCTGATGTGGGAGGAGATCTTAAGCATGTCATGTCTG ATAGCTCTTTGGATTTACCAACAGTTAGTGGCCAGCATCCTCCTGCTGCAGATATAGAGGACTTAAAATATGCTGCTTTTGGAAGCTACAGTAGCAATTT TGCAGTGAGCACACTTACAAGCTATGACTGGTCAGACAGGGATGATGCAACTCAGGGCAGAAAACTCTCTCCATTTGTCCTCTCAGCAGGAAGTGGATCC CCCTCAGCCACCTCAATTCTTCAAAAGAAAGAGACTTCATTTGGCAGTTCTGAAAACATCACCATGACATCTCTCTCCAAAGTAACGACCTTTGTAAGTG AAGATGCTCTTCCAGAGACCACCTTCCCAGCTCTTGCCAGTTTTAAAGACACGATTCCTCAGACCAGTGAGCAAAAGGAATATGAAAACAGAGACTATAA AGATTTCACAAAACAGGACCTGCCTACGGCTGAACGGAGCCAGGAGGCCACGTGTCCCAGCCCAGCGTCCAGTGGTGCCTCTCAAGAAACCCCGAACGAA TGTTCGGATGACTTTGGAGAGTTTCAAAGTGAAAAGCCCAAAATCAGCAAATTTGACTTCTTAGTAGCCACTTCACAAAGCAAAATGAAATCCAGTGAAG AAATGATCAAAAGTGAGCTGGCAACCTTTGACCTTTCTGTTCAAGGATCACACAAGAGGAGTTTGAGCCTTGGTGATAAAGAAATAAGCCGTTCTTCTCC TTCTCCAGCTTTGGAGCAGCCTTTCAGAGACCGTTCCAATACTCTGAATGAGAAGCCCGCCCTGCCCGTCATCCGAGACAAGTACAAAGACCTGACGGGA GAGGTGGAGGAAAATGAGAGATATGCATATGAATGGCAGAGATGCCTGGGGAGTGCCCTGAATGTCATTAAGAAGGCAAATGATACCTTAAATGGAATCA GTAGTAGTTCTGTTTGCACAGAAGTAATTCAGTCAGCTCAAGGCATGGAATATTTATTAGGTGTTGTTGAAGTGTACAGGGTAACCAAGCGTGTGGAGCT GGGGATAAAAGCCACTGCAGTGTGCAGTGAGAAACTCCAGCAGTTGCTGAAGGACATCGATAAAGTATGGAATAACCTAATCGGCTTCATGTCACTCGCC ACACTCACACCAGATGAAAACTCGCTGGATTTTTCCTCCTGTATGTTACGGCCTGGGATTAAAAATGCTCAGGAGCTTGCCTGTGGAGTGTGCCTCTTGA ATGTGGACTCGAGGAGCCGGGCATTCAACTCAGAAACAGACAGTTTCAAGCTGGCCTATGGAGGGCACCAGTATCACGCCAGCTGTGCCAACTTCTGGAT CAACTGTGTCGAACCAAAGCCTCCTGGCCTCGTCCTGCCTGACCTGCTCTGAACAACTCCTCTGTGAAGCATTGACTTTTTTTTTTCTGTGACACCCCAC GGGGTGACAGGGACCAATAAATAGAATGCGAGCACTGCACAGTTCGCTTCCCTGAATCGATATGAAGAACACCGCAAGGGACGGGGCCCCCGTCATCCCC ACGGCCAGTCTGCAGGACTTCAGGTAAAATTGTCCCACCCAAACTGCACGTGGCACCAGAAGCTTGCTCACTTATCTCTACTTAAGATTTTCTGAAATAC GGACCACGGCTTTCTTGATCTAAGGAAGAACTTGCTGCTGCAGTATTGAAACTGTGAAGAACTGACATTTGAAGAAAAATAGATTACCGTTGCGGGACTA GAATGGGCGACTGCTTGGAGCCAGTGCTTGTTTTTATCTAGGACACTTACTGTCCTGTGAAGTAGAATACATTTATCTGCATTTAGTTTGTTAATGTCTG AAATGAATAAAAAGAGGAAATTGCGATTAAACTGATGTTCTGCTTTTTATGGAGAAGATTCTGCCCATCTCCCCTGGACAGTAGCAGGCAGGTGAGGGCA GATTTTACCCACTTGGTTGTCACAACTGAACCAGTTCTCTACTCCTTCCCTTCACTTCTGTCCACTCTCAAGACTTTTTCCCAAAACATGCCTGGGCACT CTGCAGCCGTGAAGAATGCTCATTTTGACAGAGGCCCAAATCCTGTGTATTAGGATAATATCCTTCCCCCCGGGAGCCTTCGCTGCAAACCTGTTCTGCC GCATGCAAAGACTGTGACCATGGAGTTTTCTCAGACAAGATTTGGAAAGGCAGTGGAATGAAATCTCTTTGCAGTGGCCTCTCTCCAAATTTCCAAAGAT GACTGCATAGGGACCAACACTGCCTGACTTTGCAGTATCTGTGAGAAAAACCTGAAAATTAATTCAGGGTGAAAATGTGGAGCTCTCGGCCTAGTGTAAA GTATCAAGATGTATATTTATGGGATAGATACATGACTTAGAAGAAGTAGAAGAAAATTGTCCAGAAACAGTACTGAATTTTAGATAGAAAAGGCTCATGC TTCCTGGAGTAGGGAATTGTCTTTGCCATTTAATGTGAATGCATAAAATTAGGGGAAAAACC

refseq_AP1GBP1.F1 (forward primer)
refseq_AP1GBP1.R1 (reverse primer)
Single exon skipping

Frame 0

DKVAAAKAAAGREQDGAAARSWFWWRRGRGSWR GVRRGRRLHVSCCRWDKTPSSRPDADAATRISYG LCHAA*YARHYGNELQLSDVPRTYCYAGRNTNG TNASSGNALPRTSTLPGHASSRPTVHSRHAEAV CRRAAETI*TAAKTLRRRKKKTPV*RAEAKAQTF EQCETQDRREE*R*CFGSHKRKFRWVFQRCKNA PYSSIAPQETRPFLGGEVPSIL*YKYIWAGTN* IKYF*SWPQSPRPRFQ*EVSQFNGQ*RGCCRWMC KWYHHCRGRKYFRSKPVN*REWCGSISLTGSCS AQNASLDLQ*EFGSRCL*ENLRNHNDSNWNRYC QTVSHSDVIWASQGNSWTDMGLS*SNYTWQTYKR RTLYRSSHDSGNTEGRSCNES*CFKPVPSSSYS NFKWLFYDSAYTGESANCDTFRSCGLHAPQPWT ASHGH*PCWTSGWSCSPGF*WFHTNLPCKSGSKA RRR*LPGFSRCF*VRIP**LIQ*FPRVACFFKN K*LPAWKQCPFFVDATSWN*SIAFNGQICCV*R NCS*QVL*KYCSTWRSW**I*CFQRT*TDSRE*T FRRKLCRIQICRN**WFHRF*NSR*CITTRATN KRQNFSTILPLRNYTTETTNTSEKPSELSRPRY VFLS*LQQRETIVFFSCV*HIKISFYTTVNRFCC YYDSIGSNKNF*FG**FWRIQPFWGIFWSSTCW GAG*LCRFYGFQ**LYFI*AKAG*QI*CP*RGS QSCSSNQQRGQHSEGWTKLDCCVYQVRCLQTTFS GRVWTRC*RPER*HSFRKK***FC*LPLQ*IFF HKLGQIPGRESSGFQTHQRRLCISEVLRSPFHW WQQCWQGGL*RCTLCSV*HEIG*CGRRS*ACHV* *LFGFTNS*WPASSCCRYRGLKICCFWKLQ*QF CSEHTYKL*LVRQG*CNSGQKTLSICPLSRKWI PLSHLNSSKERDFIWQF*KHHHDISLQSNDLCK* RCSSRDHLPSSCQF*RHDSSDQ*AKGI*KQRL* RFHKTGPAYG*TEPGGHVSQPSVQWCLSRNPER MFG*LWRVSK*KAQNQQI*LLSSHFTKQNEIQ*R NDQK*AGNL*PFCSRITQEEFEPW**RNKPFFS FSSFGAAFQRPFQYSE*EARPARHPRQVQRPDG RGGGK*EICI*MAEMPGECPECH*EGK*YLKWNQ **FCLHRSNSVSSRHGIFIRCC*SVQGNQACGA GDKSHCSVQ*ETPAVAEGHR*SME*PNRLHVTR HTHTR*KLAGFFLLYVTAWD*KCSGACLWSVPLE CGLEEPGIQLRNRQFQAGLWRAPVSRQLCQLLD QLCRTKASWPRPA*PALNNSSVKH*LFFFCDTP RGDRDQ*IECEHCTVRFPESI*RTPQGTGPPSSP RPVCRTSGKIVPPKLHVAPEACSLIST*DFLKY GPRLS*SKEELAAAVLKL*RTDI*RKIDYRCGT RMGDCLEPVLVFI*DTYCPVK*NTFICI*FVNV* NE*KEEIAIKLMFCFLWRRFCPSPLDSSRQVRA DFTHLVVTTEPVLYSFPSLLSTLKTFSQNMPGH SAAVKNAHFDRGPNPVY*DNILPPGSLRCKPVLP HAKTVTMEFSQTRFGKAVE*NLFAVASLQISKD DCIGTNTA*LCSICEKNLKINSG*KCGALGLV* SIKMYIYGIDT*LRRSRRKLSRNSTEF*IEKAHA SWSRELSLPFNVNA*N*GKN

Frame 1

IRWRRRRQRQVGSKMALRPGAGSGGGGAAGAGA GSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPM VSVMQPNMQGIMGMNYSSQMSQGPIAMQAGIPMG PMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQF AEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRL LSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMH PTPASHPKKPGPSLEEKFLVSCDISTSGQEQIK LNTSEVGHKALGPGSSKKYPSLMASNGVAVDGC VSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQ PRMPPWIYNESLVPDAYKKILETTMTPTGIDTA KLYPILMSSGLPRETLGQIWALANRTTPGKLTK EELYTVLAMIAVTQRGVPAMSPDALNQFPAAPIP TLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQ PVMGINLVGPVGGAAAQASSGFIPTYPANQVVK PEEDDFQDFQDASKSGSLDDSFSDFQELPASSKT SNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKG IAADKSSENTVPPGDPGDKYSAFRELEQTAENK PLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPT KDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDM FSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSA ATMTALAATKTSSLADDFGEFSLFGEYSGLAPVG EQDDFADFMAFSNSSISSEQKPDDKYDALKEEA SPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLS LEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSS INSDKSLGEKAVAFRHTKEDSASVKSLDLPSIG GSSVGKEDSEDALSVQFDMKLADVGGDLKHVMS DSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNF AVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGS PSATSILQKKETSFGSSENITMTSLSKVTTFVS EDALPETTFPALASFKDTIPQTSEQKEYENRDYK DFTKQDLPTAERSQEATCPSPASSGASQETPNE CSDDFGEFQSEKPKISKFDFLVATSQSKMKSSE EMIKSELATFDLSVQGSHKRSLSLGDKEISRSSP SPALEQPFRDRSNTLNEKPALPVIRDKYKDLTG EVEENERYAYEWQRCLGSALNVIKKANDTLNGI SSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVEL GIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLA TLTPDENSLDFSSCMLRPGIKNAQELACGVCLL NVDSRSRAFNSETDSFKLAYGGHQYHASCANFWI NCVEPKPPGLVLPDLL*TTPL*SIDFFFSVTPH GVTGTNK*NASTAQFASLNRYEEHRKGRGPRHP HGQSAGLQVKLSHPNCTWHQKLAHLSLLKIF*NT DHGFLDLRKNLLLQY*NCEELTFEEK*ITVAGL EWATAWSQCLFLSRTLTVL*SRIHLSAFSLLMS EMNKKRKLRLN*CSAFYGEDSAHLPWTVAGR*GQ ILPTWLSQLNQFSTPSLHFCPLSRLFPKTCLGT LQP*RMLILTEAQILCIRIISFPPGAFAANLFC RMQRL*PWSFLRQDLERQWNEISLQWPLSKFPKM TA*GPTLPDFAVSVRKT*KLIQGENVELSA*CK VSRCIFMG*IHDLEEVEENCPETVLNFR*KRLM LPGVGNCLCHLM*MHKIRGKT

Frame 2

*GGGGEGSGRSGARWRCGQELVLVAAGPRELAR GPPGEAASCFLLQVG*DPLKQA*CRCSNKDFLW SLSCSLICKALWE*ITALRCPKDLLLCRQEYQW DQCQQRECLT*DKHPSWACVLQAHSTLQTCRSSL PKSSRNDLNSSKNS*KKKEKDASLKSRSKSSDF *AV*NPRQERRVEMMLWKP*KEI*MGFPEMQKC TLLQHRTPRNQALPWRRSS*YLVI*VHLGRNKLN *ILLKLATKP*AQVPVRSIPV*WPVTGLL*MDV *VVPPLQRQKILQIKTCQLKRVVWEYFPHRILL SPECLLGFTMRVWFQMPIRKS*KPQ*LQLE*ILP NCIPF*CHLGFPGKLLDRYGP*LIELHLANLQK KNFIPF*P**R*HRGAFLQ*VLML*TSSQQLLF QL*VAFL*LCLHR*VSQL*YLQVLRAPCPSALDS QSWALTLLDQWVELQPRLLVVSYQPTLQIR**S QKKMTSRIFKMLLSQDPLMTHSVISKSCLLLQK QVTPSMETVPLLC*CHFLELKHCLQWTNMLCLKE LQLTSPLKILFHLEILVINIVLSENLNRQQRIN L*EKALQNSDLQELMMVSPILKQPIVYHH*SHQ QKTKLFHHPSPQELYNRNNKHK*KTL*T*QT*IC FPQLIAAARNHCLFQLCLAHQNQFLHHSQQVLL LL*QHWQQQKLLVWLMILENSAFLGNILV*HLL GSRMTLQILWLSVIALFHLSKSRMTNMMPLKRKP VLFL*PATWAAQ*RVDKTRLLRLPSTMSSDNFL WKGLD*VLKT*KITLLQEKVMMILLTSTPVNFL P*TRTNPWERKQWLSDTPKKTLHQ*SP*ISLPLV AAVLARRTLKMHSLFSLT*NWLMWEEILSMSCL IALWIYQQLVASILLLQI*RT*NMLLLEATVAI LQ*AHLQAMTGQTGMMQLRAENSLHLSSQQEVDP PQPPQFFKRKRLHLAVLKTSP*HLSPK*RPL*V KMLFQRPPSQLLPVLKTRFLRPVSKRNMKTETI KISQNRTCLRLNGARRPRVPAQRPVVPLKKPRTN VRMTLESFKVKSPKSANLTS**PLHKAK*NPVK K*SKVSWQPLTFLFKDHTRGV*ALVIKK*AVLL LLQLWSSLSETVPIL*MRSPPCPSSETSTKT*RE RWRKMRDMHMNGRDAWGVP*MSLRRQMIP*MES VVVLFAQK*FSQLKAWNIY*VLLKCTG*PSVWS WG*KPLQCAVRNSSSC*RTSIKYGIT*SASCHSP HSHQMKTRWIFPPVCYGLGLKMLRSLPVECAS* MWTRGAGHSTQKQTVSSWPMEGTSITPAVPTSG STVSNQSLLASSCLTCSEQLLCEALTFFFL*HPT G*QGPINRMRALHSSLP*IDMKNTARDGAPVIP TASLQDFR*NCPTQTARGTRSLLTYLYLRFSEI RTTAFLI*GRTCCCSIETVKN*HLKKNRLPLRD* NGRLLGASACFYLGHLLSCEVEYIYLHLVC*CL K*IKRGNCD*TDVLLFMEKILPISPGQ*QAGEG RFYPLGCHN*TSSLLLPFTSVHSQDFFPKHAWAL CSREECSF*QRPKSCVLG*YPSPREPSLQTCSA ACKDCDHGVFSDKIWKGSGMKSLCSGLSPNFQR *LHRDQHCLTLQYL*EKPEN*FRVKMWSSRPSVK YQDVYLWDRYMT*KK*KKIVQKQY*ILDRKGSC FLE*GIVFAI*CECIKLGEK

Sequence NM_007247

GATAAGGTGGCGGCGGCGAAGGCAGCGGCAGGTCGGGAGCAAGATGGCGCTGCGGCCAGGAGCTGGTTCTGGTGGCGGCGGGGCCGCGGGAGCTGGCGCG GGGTCCGCCGGGGGAGGCGGCTTCATGTTTCCTGTTGCAGGTGGGATAAGACCCCCTCAAGCAGGCCTGATGCCGATGCAGCAACAAGGATTTCCTATGG TCTCTGTCATGCAGCCTAATATGCAAGGCATTATGGGAATGAATTACAGCTCTCAGATGTCCCAAGGACCTATTGCTATGCAGGCAGGAATACCAATGGG ACCAATGCCAGCAGCGGGAATGCCTTACCTAGGACAAGCACCCTTCCTGGGCATGCGTCCTCCAGGCCCACAGTACACTCCAGACATGCAGAAGCAGTTT GCCGAAGAGCAGCAGAAACGATTTGAACAGCAGCAAAAACTCTTAGAAGAAGAAAGAAAAAGACGCCAGTTTGAAGAGCAGAAGCAAAAGCTCAGACTTT TGAGCAGTGTGAAACCCAAGACAGGAGAGAAGAGTAGAGATGATGCTTTGGAAGCCATAAAAGGAAATTTAGATGGGTTTTCCAGAGATGCAAAAATGCA CCCTACTCCAGCATCGCACCCCAAGAAACCAGGCCCTTCCTTGGAGGAGAAGTTCCTAGTATCTTGTGATATAAGTACATCTGGGCAGGAACAAATTAAA TTAAATACTTCTGAAGTTGGCCACAAAGCCCTAGGCCCAGGTTCCAGTAAGAAGTATCCCAGTTTAATGGCCAGTAACGGGGTTGCTGTAGATGGATGTG TAAGTGGTACCACCACTGCAGAGGCAGAAAATACTTCAGATCAAAACCTGTCAATTGAAGAGAGTGGTGTGGGAGTATTTCCCTCACAGGATCCTGCTCA GCCCAGAATGCCTCCTTGGATTTACAATGAGAGTTTGGTTCCAGATGCCTATAAGAAAATCTTAGAAACCACAATGACTCCAACTGGAATAGATACTGCC AAACTGTATCCCATTCTGATGTCATCTGGGCTTCCCAGGGAAACTCTTGGACAGATATGGGCCTTAGCTAATCGAACTACACCTGGCAAACTTACAAAAG AAGAACTTTATACCGTTCTAGCCATGATAGCGGTAACACAGAGGGGCGTTCCTGCAATGAGTCCTGATGCTTTAAACCAGTTCCCAGCAGCTCCTATTCC AACTTTAAGTGGCTTTTCTATGACTCTGCCTACACCGGTGAGTCAGCCAACTGTGATACCTTCAGGTCCTGCGGGCTCCATGCCCCTCAGCCTTGGACAG CCAGTCATGGGCATTAACCTTGTTGGACCAGTGGGTGGAGCTGCAGCCCAGGCTTCTAGTGGTTTCATACCAACCTACCCTGCAAATCAGGTAGTAAAGC CAGAAGAAGATGACTTCCAGGATTTTCAAGATGCTTCTAAGTCAGGATCCCTTGATGACTCATTCAGTGATTTCCAAGAGTTGCCTGCTTCTTCAAAAAC AAGTAACTCCCAGCATGGAAACAGTGCCCCTTCTTTGTTGATGCCACTTCCTGGAACTAAAGCATTGCCTTCAATGGACAAATATGCTGTGTTTAAAGGA ATTGCAGCTGACAAGTCCTCTGAAAATACTGTTCCACCTGGAGATCCTGGTGATAAATATAGTGCTTTCAGAGAACTTGAACAGACAGCAGAGAATAAAC CTTTAGGAGAAAGCTTTGCAGAATTCAGATCTGCAGGAACTGATGATGGTTTCACCGATTTTAAAACAGCCGATAGTGTATCACCACTAGAGCCACCAAC AAAAGACAAAACTTTTCCACCATCCTTCCCCTCAGGAACTATACAACAGAAACAACAAACACAAGTGAAAAACCCTCTGAACTTAGCAGACCTAGATATG TTTTCCTCAGTTAATTGCAGCAGCGAGAAACCATTGTCTTTTTCAGCTGTGTTTAGCACATCAAAATCAGTTTCTACACCACAGTCAACAGGTTCTGCTG CTACTATGACAGCATTGGCAGCAACAAAAACTTCTAGTTTGGCTGATGATTTTGGAGAATTCAGCCTTTTTGGGGAATATTCTGGTCTAGCACCTGTTGG GGAGCAGGATGACTTTGCAGATTTTATGGCTTTCAGTAATAGCTCTATTTCATCTGAGCAAAAGCCGGATGACAAATATGATGCCCTTAAAGAGGAAGCC AGTCCTGTTCCTCTAACCAGCAACGTGGGCAGCACAGTGAAGGGTGGACAAAACTCGACTGCTGCGTCTACCAAGTACGATGTCTTCAGACAACTTTCTC TGGAAGGGTCTGGACTAGGTGTTGAAGACCTGAAAGATAACACTCCTTCAGGAAAAAGTGATGATGATTTTGCTGACTTCCACTCCAGTAAATTTTCTTC CATAAACTCGGACAAATCCCTGGGAGAGAAAGCAGTGGCTTTCAGACACACCAAAGAAGACTCTGCATCAGTGAAGTCCTTAGATCTCCCTTCCATTGGT GGCAGCAGTGTTGGCAAGGAGGACTCTGAAGATGCACTCTCTGTTCAGTTTGACATGAAATTGGCTGATGTGGGAGGAGATCTTAAGCATGTCATGTCTG ATAGCTCTTTGGATTTACCAACAGTTAGTGGCCAGCATCCTCCTGCTGCAGATATAGAGGACTTAAAATATGCTGCTTTTGGAAGCTACAGTAGCAATTT TGCAGTGAGCACACTTACAAGCTATGACTGGTCAGACAGGGATGATGCAACTCAGGGCAGAAAACTCTCTCCATTTGTCCTCTCAGCAGGAAGTGGATCC CCCTCAGCCACCTCAATTCTTCAAAAGAAAGAGACTTCATTTGGCAGTTCTGAAAACATCACCATGACATCTCTCTCCAAAGTAACGACCTTTGTAAGTG AAGATGCTCTTCCAGAGACCACCTTCCCAGCTCTTGCCAGTTTTAAAGACACGATTCCTCAGACCAGTGAGCAAAAGGAATATGAAAACAGAGACTATAA AGATTTCACAAAACAGGACCTGCCTACGGCTGAACGGAGCCAGGAGGCCACGTGTCCCAGCCCAGCGTCCAGTGGTGCCTCTCAAGAAACCCCGAACGAA TGTTCGGATGACTTTGGAGAGTTTCAAAGTGAAAAGCCCAAAATCAGCAAATTTGACTTCTTAGTAGCCACTTCACAAAGCAAAATGAAATCCAGTGAAG AAATGATCAAAAGTGAGCTGGCAACCTTTGACCTTTCTGTTCAAGGATCACACAAGAGGAGTTTGAGCCTTGGTGATAAAGAAATAAGCCGTTCTTCTCC TTCTCCAGCTTTGGAGCAGCCTTTCAGAGACCGTTCCAATACTCTGAATGAGAAGCCCGCCCTGCCCGTCATCCGAGACAAGTACAAAGACCTGACGGGA GAGGTGGAGGAAAATGAGAGATATGCATATGAATGGCAGAGATGCCTGGGGAGTGCCCTGAATGTCATTAAGAAGGCAAATGATACCTTAAATGGAATCA GTAGTAGTTCTGTTTGCACAGAAGTAATTCAGTCAGCTCAAGGCATGGAATATTTATTAGGTGTTGTTGAAGTGTACAGGGTAACCAAGCGTGTGGAGCT GGGGATAAAAGCCACTGCAGTGTGCAGTGAGAAACTCCAGCAGTTGCTGAAGGACATCGATAAAGTATGGAATAACCTAATCGGCTTCATGTCACTCGCC ACACTCACACCAGATGAAAACTCGCTGGATTTTTCCTCCTGTATGTTACGGCCTGGGATTAAAAATGCTCAGGAGCTTGCCTGTGGAGTGTGCCTCTTGA ATGTGGACTCGAGGAGCCGGAAAGAAGAGAAGCCTGCAGAAGAACATCCTAAAAAAGCATTCAACTCAGAAACAGACAGTTTCAAGCTGGCCTATGGAGG GCACCAGTATCACGCCAGCTGTGCCAACTTCTGGATCAACTGTGTCGAACCAAAGCCTCCTGGCCTCGTCCTGCCTGACCTGCTCTGAACAACTCCTCTG TGAAGCATTGACTTTTTTTTTTCTGTGACACCCCACGGGGTGACAGGGACCAATAAATAGAATGCGAGCACTGCACAGTTCGCTTCCCTGAATCGATATG AAGAACACCGCAAGGGACGGGGCCCCCGTCATCCCCACGGCCAGTCTGCAGGACTTCAGGTAAAATTGTCCCACCCAAACTGCACGTGGCACCAGAAGCT TGCTCACTTATCTCTACTTAAGATTTTCTGAAATACGGACCACGGCTTTCTTGATCTAAGGAAGAACTTGCTGCTGCAGTATTGAAACTGTGAAGAACTG ACATTTGAAGAAAAATAGATTACCGTTGCGGGACTAGAATGGGCGACTGCTTGGAGCCAGTGCTTGTTTTTATCTAGGACACTTACTGTCCTGTGAAGTA GAATACATTTATCTGCATTTAGTTTGTTAATGTCTGAAATGAATAAAAAGAGGAAATTGCGATTAAACTGATGTTCTGCTTTTTATGGAGAAGATTCTGC CCATCTCCCCTGGACAGTAGCAGGCAGGTGAGGGCAGATTTTACCCACTTGGTTGTCACAACTGAACCAGTTCTCTACTCCTTCCCTTCACTTCTGTCCA CTCTCAAGACTTTTTCCCAAAACATGCCTGGGCACTCTGCAGCCGTGAAGAATGCTCATTTTGACAGAGGCCCAAATCCTGTGTATTAGGATAATATCCT TCCCCCCGGGAGCCTTCGCTGCAAACCTGTTCTGCCGCATGCAAAGACTGTGACCATGGAGTTTTCTCAGACAAGATTTGGAAAGGCAGTGGAATGAAAT CTCTTTGCAGTGGCCTCTCTCCAAATTTCCAAAGATGACTGCATAGGGACCAACACTGCCTGACTTTGCAGTATCTGTGAGAAAAACCTGAAAATTAATT CAGGGTGAAAATGTGGAGCTCTCGGCCTAGTGTAAAGTATCAAGATGTATATTTATGGGATAGATACATGACTTAGAAGAAGTAGAAGAAAATTGTCCAG AAACAGTACTGAATTTTAGATAGAAAAGGCTCATGCTTCCTGGAGTAGGGAATTGTCTTTGCCATTTAATGTGAATGCATAAAATTAGGGGAAAAACC

refseq_AP1GBP1.F1 (forward primer)
refseq_AP1GBP1.R1 (reverse primer)
Single exon skipping

Frame 0

DKVAAAKAAAGREQDGAAARSWFWWRRGRGSWR GVRRGRRLHVSCCRWDKTPSSRPDADAATRISYG LCHAA*YARHYGNELQLSDVPRTYCYAGRNTNG TNASSGNALPRTSTLPGHASSRPTVHSRHAEAV CRRAAETI*TAAKTLRRRKKKTPV*RAEAKAQTF EQCETQDRREE*R*CFGSHKRKFRWVFQRCKNA PYSSIAPQETRPFLGGEVPSIL*YKYIWAGTN* IKYF*SWPQSPRPRFQ*EVSQFNGQ*RGCCRWMC KWYHHCRGRKYFRSKPVN*REWCGSISLTGSCS AQNASLDLQ*EFGSRCL*ENLRNHNDSNWNRYC QTVSHSDVIWASQGNSWTDMGLS*SNYTWQTYKR RTLYRSSHDSGNTEGRSCNES*CFKPVPSSSYS NFKWLFYDSAYTGESANCDTFRSCGLHAPQPWT ASHGH*PCWTSGWSCSPGF*WFHTNLPCKSGSKA RRR*LPGFSRCF*VRIP**LIQ*FPRVACFFKN K*LPAWKQCPFFVDATSWN*SIAFNGQICCV*R NCS*QVL*KYCSTWRSW**I*CFQRT*TDSRE*T FRRKLCRIQICRN**WFHRF*NSR*CITTRATN KRQNFSTILPLRNYTTETTNTSEKPSELSRPRY VFLS*LQQRETIVFFSCV*HIKISFYTTVNRFCC YYDSIGSNKNF*FG**FWRIQPFWGIFWSSTCW GAG*LCRFYGFQ**LYFI*AKAG*QI*CP*RGS QSCSSNQQRGQHSEGWTKLDCCVYQVRCLQTTFS GRVWTRC*RPER*HSFRKK***FC*LPLQ*IFF HKLGQIPGRESSGFQTHQRRLCISEVLRSPFHW WQQCWQGGL*RCTLCSV*HEIG*CGRRS*ACHV* *LFGFTNS*WPASSCCRYRGLKICCFWKLQ*QF CSEHTYKL*LVRQG*CNSGQKTLSICPLSRKWI PLSHLNSSKERDFIWQF*KHHHDISLQSNDLCK* RCSSRDHLPSSCQF*RHDSSDQ*AKGI*KQRL* RFHKTGPAYG*TEPGGHVSQPSVQWCLSRNPER MFG*LWRVSK*KAQNQQI*LLSSHFTKQNEIQ*R NDQK*AGNL*PFCSRITQEEFEPW**RNKPFFS FSSFGAAFQRPFQYSE*EARPARHPRQVQRPDG RGGGK*EICI*MAEMPGECPECH*EGK*YLKWNQ **FCLHRSNSVSSRHGIFIRCC*SVQGNQACGA GDKSHCSVQ*ETPAVAEGHR*SME*PNRLHVTR HTHTR*KLAGFFLLYVTAWD*KCSGACLWSVPLE CGLEEPERREACRRTS*KSIQLRNRQFQAGLWR APVSRQLCQLLDQLCRTKASWPRPA*PALNNSS VKH*LFFFCDTPRGDRDQ*IECEHCTVRFPESI* RTPQGTGPPSSPRPVCRTSGKIVPPKLHVAPEA CSLIST*DFLKYGPRLS*SKEELAAAVLKL*RT DI*RKIDYRCGTRMGDCLEPVLVFI*DTYCPVK* NTFICI*FVNV*NE*KEEIAIKLMFCFLWRRFC PSPLDSSRQVRADFTHLVVTTEPVLYSFPSLLS TLKTFSQNMPGHSAAVKNAHFDRGPNPVY*DNIL PPGSLRCKPVLPHAKTVTMEFSQTRFGKAVE*N LFAVASLQISKDDCIGTNTA*LCSICEKNLKIN SG*KCGALGLV*SIKMYIYGIDT*LRRSRRKLSR NSTEF*IEKAHASWSRELSLPFNVNA*N*GKN

Frame 1

IRWRRRRQRQVGSKMALRPGAGSGGGGAAGAGA GSAGGGGFMFPVAGGIRPPQAGLMPMQQQGFPM VSVMQPNMQGIMGMNYSSQMSQGPIAMQAGIPMG PMPAAGMPYLGQAPFLGMRPPGPQYTPDMQKQF AEEQQKRFEQQQKLLEEERKRRQFEEQKQKLRL LSSVKPKTGEKSRDDALEAIKGNLDGFSRDAKMH PTPASHPKKPGPSLEEKFLVSCDISTSGQEQIK LNTSEVGHKALGPGSSKKYPSLMASNGVAVDGC VSGTTTAEAENTSDQNLSIEESGVGVFPSQDPAQ PRMPPWIYNESLVPDAYKKILETTMTPTGIDTA KLYPILMSSGLPRETLGQIWALANRTTPGKLTK EELYTVLAMIAVTQRGVPAMSPDALNQFPAAPIP TLSGFSMTLPTPVSQPTVIPSGPAGSMPLSLGQ PVMGINLVGPVGGAAAQASSGFIPTYPANQVVK PEEDDFQDFQDASKSGSLDDSFSDFQELPASSKT SNSQHGNSAPSLLMPLPGTKALPSMDKYAVFKG IAADKSSENTVPPGDPGDKYSAFRELEQTAENK PLGESFAEFRSAGTDDGFTDFKTADSVSPLEPPT KDKTFPPSFPSGTIQQKQQTQVKNPLNLADLDM FSSVNCSSEKPLSFSAVFSTSKSVSTPQSTGSA ATMTALAATKTSSLADDFGEFSLFGEYSGLAPVG EQDDFADFMAFSNSSISSEQKPDDKYDALKEEA SPVPLTSNVGSTVKGGQNSTAASTKYDVFRQLS LEGSGLGVEDLKDNTPSGKSDDDFADFHSSKFSS INSDKSLGEKAVAFRHTKEDSASVKSLDLPSIG GSSVGKEDSEDALSVQFDMKLADVGGDLKHVMS DSSLDLPTVSGQHPPAADIEDLKYAAFGSYSSNF AVSTLTSYDWSDRDDATQGRKLSPFVLSAGSGS PSATSILQKKETSFGSSENITMTSLSKVTTFVS EDALPETTFPALASFKDTIPQTSEQKEYENRDYK DFTKQDLPTAERSQEATCPSPASSGASQETPNE CSDDFGEFQSEKPKISKFDFLVATSQSKMKSSE EMIKSELATFDLSVQGSHKRSLSLGDKEISRSSP SPALEQPFRDRSNTLNEKPALPVIRDKYKDLTG EVEENERYAYEWQRCLGSALNVIKKANDTLNGI SSSSVCTEVIQSAQGMEYLLGVVEVYRVTKRVEL GIKATAVCSEKLQQLLKDIDKVWNNLIGFMSLA TLTPDENSLDFSSCMLRPGIKNAQELACGVCLL NVDSRSRKEEKPAEEHPKKAFNSETDSFKLAYGG HQYHASCANFWINCVEPKPPGLVLPDLL*TTPL *SIDFFFSVTPHGVTGTNK*NASTAQFASLNRY EEHRKGRGPRHPHGQSAGLQVKLSHPNCTWHQKL AHLSLLKIF*NTDHGFLDLRKNLLLQY*NCEEL TFEEK*ITVAGLEWATAWSQCLFLSRTLTVL*S RIHLSAFSLLMSEMNKKRKLRLN*CSAFYGEDSA HLPWTVAGR*GQILPTWLSQLNQFSTPSLHFCP LSRLFPKTCLGTLQP*RMLILTEAQILCIRIIS FPPGAFAANLFCRMQRL*PWSFLRQDLERQWNEI SLQWPLSKFPKMTA*GPTLPDFAVSVRKT*KLI QGENVELSA*CKVSRCIFMG*IHDLEEVEENCP ETVLNFR*KRLMLPGVGNCLCHLM*MHKIRGKT

Frame 2

*GGGGEGSGRSGARWRCGQELVLVAAGPRELAR GPPGEAASCFLLQVG*DPLKQA*CRCSNKDFLW SLSCSLICKALWE*ITALRCPKDLLLCRQEYQW DQCQQRECLT*DKHPSWACVLQAHSTLQTCRSSL PKSSRNDLNSSKNS*KKKEKDASLKSRSKSSDF *AV*NPRQERRVEMMLWKP*KEI*MGFPEMQKC TLLQHRTPRNQALPWRRSS*YLVI*VHLGRNKLN *ILLKLATKP*AQVPVRSIPV*WPVTGLL*MDV *VVPPLQRQKILQIKTCQLKRVVWEYFPHRILL SPECLLGFTMRVWFQMPIRKS*KPQ*LQLE*ILP NCIPF*CHLGFPGKLLDRYGP*LIELHLANLQK KNFIPF*P**R*HRGAFLQ*VLML*TSSQQLLF QL*VAFL*LCLHR*VSQL*YLQVLRAPCPSALDS QSWALTLLDQWVELQPRLLVVSYQPTLQIR**S QKKMTSRIFKMLLSQDPLMTHSVISKSCLLLQK QVTPSMETVPLLC*CHFLELKHCLQWTNMLCLKE LQLTSPLKILFHLEILVINIVLSENLNRQQRIN L*EKALQNSDLQELMMVSPILKQPIVYHH*SHQ QKTKLFHHPSPQELYNRNNKHK*KTL*T*QT*IC FPQLIAAARNHCLFQLCLAHQNQFLHHSQQVLL LL*QHWQQQKLLVWLMILENSAFLGNILV*HLL GSRMTLQILWLSVIALFHLSKSRMTNMMPLKRKP VLFL*PATWAAQ*RVDKTRLLRLPSTMSSDNFL WKGLD*VLKT*KITLLQEKVMMILLTSTPVNFL P*TRTNPWERKQWLSDTPKKTLHQ*SP*ISLPLV AAVLARRTLKMHSLFSLT*NWLMWEEILSMSCL IALWIYQQLVASILLLQI*RT*NMLLLEATVAI LQ*AHLQAMTGQTGMMQLRAENSLHLSSQQEVDP PQPPQFFKRKRLHLAVLKTSP*HLSPK*RPL*V KMLFQRPPSQLLPVLKTRFLRPVSKRNMKTETI KISQNRTCLRLNGARRPRVPAQRPVVPLKKPRTN VRMTLESFKVKSPKSANLTS**PLHKAK*NPVK K*SKVSWQPLTFLFKDHTRGV*ALVIKK*AVLL LLQLWSSLSETVPIL*MRSPPCPSSETSTKT*RE RWRKMRDMHMNGRDAWGVP*MSLRRQMIP*MES VVVLFAQK*FSQLKAWNIY*VLLKCTG*PSVWS WG*KPLQCAVRNSSSC*RTSIKYGIT*SASCHSP HSHQMKTRWIFPPVCYGLGLKMLRSLPVECAS* MWTRGAGKKRSLQKNILKKHSTQKQTVSSWPME GTSITPAVPTSGSTVSNQSLLASSCLTCSEQLLC EALTFFFL*HPTG*QGPINRMRALHSSLP*IDM KNTARDGAPVIPTASLQDFR*NCPTQTARGTRS LLTYLYLRFSEIRTTAFLI*GRTCCCSIETVKN* HLKKNRLPLRD*NGRLLGASACFYLGHLLSCEV EYIYLHLVC*CLK*IKRGNCD*TDVLLFMEKIL PISPGQ*QAGEGRFYPLGCHN*TSSLLLPFTSVH SQDFFPKHAWALCSREECSF*QRPKSCVLG*YP SPREPSLQTCSAACKDCDHGVFSDKIWKGSGMK SLCSGLSPNFQR*LHRDQHCLTLQYL*EKPEN*F RVKMWSSRPSVKYQDVYLWDRYMT*KK*KKIVQ KQY*ILDRKGSCFLE*GIVFAI*CECIKLGEK