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Sequences

Sequence NM_020987

GGACACCATCATTTGGGTTTTTAAAAGCTTCAGCTTCTCCAGCATCTTTGCATTGTGAATATCTTCCTGCTTCTAGTCAAAGCTTTCTCTCTAGTGATTG
GAATGCTGCTGTAAGCCTGATTAGAGGTGCCTGAGGATATCACCTTTTACAAGGAAGCCGTGTGTGCTTGAGAGGATCTTTTTAAATGCATTATGGCTCA
TGCAGCCTCACAATTAAAGAAAAACAGGGATTTAGAAATCAATGCTGAAGAAGAGCCTGAGAAAAAAAGGAAACACCGCAAACGGTCCCGGGATCGGAAG
AAAAAGTCTGATGCCAATGCAAGTTACTTAAGAGCAGCTCGAGCTGGACACCTTGAAAAGGCCCTCGACTACATAAAAAATGGAGTTGACATCAACATTT
GCAATCAGAATGGGTTGAACGCTCTCCACCTTGCTTCCAAAGAAGGCCATGTAGAGGTTGTTTCTGAGCTGCTGCAGAGAGAAGCCAATGTGGATGCAGC
TACAAAGAAAGGAAACACAGCATTGCACATCGCATCTTTGGCTGGGCAAGCAGAGGTGGTAAAAGTCTTGGTTACAAATGGAGCCAATGTCAATGCACAA
TCTCAGAATGGTTTCACGCCATTGTATATGGCAGCCCAGGAAAATCACCTGGAAGTTGTCAAGTTTCTTCTTGACAATGGTGCAAGCCAGAGCCTAGCCA
CAGAGGATGGCTTCACACCATTGGCAGTGGCTTTGCAACAAGGTCACGACCAAGTCGTTTCGCTCCTGCTAGAGAATGACACCAAAGGAAAAGTGCGTCT
CCCAGCTCTTCATATCGCGGCCCGAAAAGACGACACGAAAGCCGCCGCCCTGCTGCTGCAGAATGACAACAATGCAGATGTGGAATCAAAGAGTGGCTTC
ACTCCGCTCCACATAGCTGCTCACTATGGAAATATCAATGTAGCCACGTTGCTGTTAAACCGAGCGGCTGCTGTGGATTTCACCGCAAGGAATGACATCA
CTCCTTTACATGTTGCATCAAAAAGAGGAAATGCAAATATGGTAAAACTATTGCTCGATCGAGGAGCTAAAATCGATGCCAAAACCAGGGATGGTCTGAC
ACCACTGCACTGTGGAGCAAGGAGTGGCCACGAGCAGGTGGTAGAAATGTTGCTTGATCGAGCTGCCCCCATTCTTTCAAAAACCAAGAATGGATTATCT
CCATTGCACATGGCCACACAAGGGGATCATTTAAACTGCGTCCAGCTTCTCCTCCAGCATAATGTACCCGTGGATGATGTCACCAATGACTACCTGACTG
CCCTACACGTGGCTGCCCACTGTGGCCATTACAAAGTTGCCAAGGTTCTCTTGGATAAGAAAGCTAACCCCAATGCCAAAGCCCTGAATGGCTTTACCCC
TCTTCATATTGCCTGCAAGAAGAATCGAATTAAAGTAATGGAACTCCTTCTGAAACACGGTGCATCCATCCAAGCTGTAACCGAGTCGGGCCTTACCCCA
ATCCATGTTGCTGCCTTCATGGGGCATGTAAATATTGTATCACAACTAATGCATCATGGAGCCTCACCAAACACCACCAATGTGAGAGGAGAAACAGCAC
TGCACATGGCAGCTCGCTCCGGCCAAGCTGAAGTTGTGCGGTATCTGGTACAAGACGGAGCTCAGGTAGAAGCTAAAGCTAAGGATGACCAAACACCACT
CCACATTTCAGCCCGACTGGGGAAAGCAGACATAGTACAACAGCTGTTGCAGCAAGGGGCATCTCCAAATGCAGCCACAACTTCTGGGTACACCCCACTT
CACCTTTCCGCCCGAGAGGGGCATGAGGATGTGGCCGCGTTCCTTTTGGATCATGGAGCGTCTTTATCTATAACAACAAAGAAAGGATTTACTCCTCTTC
ATGTGGCAGCAAAATATGGAAAGCTTGAAGTCGCCAATCTCCTGCTACAGAAAAGTGCATCTCCAGATGCTGCTGGGAAGAGCGGGCTAACACCACTGCA
TGTAGCTGCACATTACGATAATCAGAAAGTGGCCCTTCTGCTTTTGGACCAAGGAGCCTCACCTCACGCAGCCGCAAAGAATGGTTATACGCCACTGCAC
ATCGCTGCCAAAAAGAACCAGATGGACATAGCGACAACTCTGCTGGAATATGGTGCTGATGCCAACGCAGTTACCCGGCAAGGAATTGCTTCCGTCCATC
TCGCAGCTCAGGAAGGGCACGTGGACATGGTGTCGCTGCTCCTCGGTAGAAATGCGAATGTGAACCTGAGCAATAAGAGCGGCCTGACCCCACTCCATTT
GGCTGCTCAAGAAGATCGAGTGAATGTGGCAGAAGTCCTCGTAAACCAAGGGGCTCATGTGGACGCCCAGACAAAGATGGGATACACACCACTGCATGTG
GGCTGCCACTATGGAAATATCAAGATTGTTAATTTCCTGCTCCAGCATTCTGCAAAAGTTAATGCCAAAACAAAGAATGGGTATACGCCATTACATCAAG
CAGCACAGCAGGGGCATACGCATATAATAAATGTCTTACTTCAGAACAACGCCTCCCCCAATGAACTCACTGTGAATGGGAATACTGCCCTTGGCATTGC
CCGGCGCCTCGGCTACATCTCAGTAGTGGACACCCTGAAGATAGTGACCGAAGAGACCATGACCACAACTACTGTCACAGAGAAGCACAAAATGAATGTT
CCAGAAACGATGAATGAAGTTCTTGATATGTCTGATGATGAAGTTCGTAAAGCCAATGCCCCTGAAATGCTCAGTGATGGCGAATATATCTCAGATGTTG
AAGAAGGTGAAGATGCAATGACCGGGGACACAGACAAATATCTTGGGCCACAGGACCTTAAGGAATTGGGTGATGATTCCCTGCCTGCAGAGGGTTACAT
GGGCTTTAGTCTCGGAGCGCGTTCTGCCAGCCTCCGCTCCTTCAGTTCGGATAGGTCTTACACCTTGAACAGAAGCTCCTATGCACGGGACAGCATGATG
ATTGAAGAACTCCTTGTGCCATCCAAAGAGCAGCATCTAACATTCACAAGGGAATTTGATTCAGATTCTCTTAGACATTACAGCTGGGCTGCAGACACCT
TAGACAATGTCAATCTTGTTTCAAGCCCCATTCATTCTGGGTTTCTGGTTAGCTTTATGGTGGACGCGAGAGGGGGCTCCATGAGAGGAAGCCGTCATCA
CGGGATGAGAATCATCATTCCTCCACGCAAGTGTACGGCCCCCACTCGAATCACCTGCCGTTTGGTAAAGAGACATAAACTGGCCAACCCACCCCCCATG
GTGGAAGGAGAGGGATTAGCCAGTAGGCTGGTAGAAATGGGTCCTGCAGGGGCACAATTTTTAGGCCCTGTCATAGTGGAAATCCCTCACTTTGGGTCCA
TGAGAGGAAAAGAGAGAGAACTCATTGTTCTTCGAAGTGAAAATGGTGAAACTTGGAAGGAGCATCAGTTTGACAGCAAAAATGAAGATTTAACCGAGTT
ACTTAATGGCATGGATGAAGAACTTGATAGCCCAGAAGAGTTAGGGAAAAAGCGTATCTGCAGGATTATCACGAAAGATTTCCCCCAGTATTTTGCAGTG
GTTTCCCGGATTAAGCAGGAAAGCAACCAGATTGGTCCTGAAGGTGGAATTCTGAGCAGCACCACAGTGCCCCTTGTTCAAGCATCTTTCCCAGAGGGTG
CCCTAACTAAAAGAATTCGAGTGGGCCTCCAGGCCCAGCCTGTTCCAGATGAAATTGTGAAAAAGATCCTTGGAAACAAAGCAACTTTTAGCCCAATTGT
CACTGTGGAACCAAGAAGACGGAAATTCCATAAACCAATCACAATGACCATTCCGGTGCCCCCGCCCTCAGGAGAAGGTGTATCCAATGGATACAAAGGG
GACACTACACCCAATCTGCGTCTTCTCTGTAGCATTACAGGGGGCACTTCGCCTGCTCAGTGGGAAGACATCACAGGAACAACTCCTTTGACGTTTATAA
AAGATTGTGTCTCCTTTACAACCAATGTTTCAGCCAGATTTTGGCTTGCAGACTGCCATCAAGTTTTAGAAACTGTGGGGTTAGCCACGCAACTGTACAG
AGAATTGATATGTGTTCCATATATGGCCAAGTTTGTTGTTTTTGCCAAAATGAATGATCCCGTAGAATCTTCCTTGCGATGTTTCTGCATGACAGATGAC
AAAGTGGACAAAACTTTAGAGCAACAAGAGAATTTTGAGGAAGTCGCAAGAAGCAAAGATATTGAGGTTCTGGAAGGAAAACCTATTTATGTTGATTGTT
ATGGAAATTTGGCCCCACTTACCAAAGGAGGACAGCAACTTGTTTTTAACTTTTATTCTTTCAAAGAAAATAGACTGCCATTTTCCATCAAGATTAGAGA
CACCAGCCAAGAGCCCTGTGGTCGTCTGTCTTTTCTGAAAGAACCAAAGACAACAAAAGGACTGCCTCAAACAGCGGTTTGCAACTTAAATATCACTCTG
CCAGCACATAAAAAGGAGACAGAGTCAGATCAAGATGATGAGATTGAGAAAACAGATAGACGACAGAGCTTCGCATCCTTAGCTTTACGTAAGCGCTACA
GCTACTTGACTGAGCCTGGAATGATTGAACGGAGTACAGGAGCAACAAGATCCCTCCCCACCACTTACTCATACAAGCCATTCTTTTCTACAAGACCATA
CCAGTCCTGGACAACAGCTCCGATTACAGTGCCTGGGCCAGCCAAGTCAGGCTTCACTTCCTTATCAAGTTCTTCCTCTAATACGCCATCAGCTTCTCCG
TTAAAATCAATATGGTCTGTTTCGACACCTTCTCCAATCAAATCCACATTAGGCGCGTCAACTACATCTTCAGTTAAATCCATTAGTGACGTGGCATCTC
CAATTAGATCCTTTCGGACAATGTCTTCGCCGATAAAAACTGTGGTGTCACAATCTCCATACAATATCCAAGTTTCCTCTGGTACCCTGGCTAGAGCTCC
AGCAGTCACGGAAGCTACGCCCTTAAAAGGGCTGGCATCCAATTCTACGTTTTCCTCTCGAACCTCTCCAGTGACTACAGCAGGGTCTCTTTTGGAGAGG
TCATCAATTACTATGACACCCCCTGCCTCCCCCAAATCAAACATTAATATGTATTCCTCAAGTTTGCCATTTAAGTCAATTATTACATCAGCAGCACCGC
TAATATCTTCACCTTTAAAGTCAGTGGTGTCTCCAGTTAAATCAGCAGTTGATGTCATTTCATCAGCCAAAATTACAATGGCATCTTCTCTCTCATCACC
TGTGAAGCAGATGCCTGGACATGCAGAGGTAGCATTAGTCAATGGATCTATTTCCCCTCTAAAATATCCATCATCCTCAACTTTAATTAATGGATGCAAA
GCCACTGCCACGTTACAGGAAAAAATTTCTTCTGCTACAAACTCTGTGAGCTCTGTGGTCAGTGCAGCCACTGACACAGTTGAGAAAGTGTTTTCTACCA
CGACTGCAATGCCATTTTCCCCACTCAGGTCATATGTTTCTGCAGCACCATCAGCTTTTCAGTCTCTAAGAACTCCTTCCGCAAGTGCACTCTATACATC
CCTTGGGTCGTCAATATCTGCAACTACCTCATCTGTAACTTCATCAATTATAACAGTGCCAGTATACTCTGTAGTCAATGTTTTGCCAGAACCAGCATTA
AAGAAACTTCCAGACTCTAATTCATTTACAAAATCAGCAGCAGCCTTGCTGTCACCCATTAAAACATTGACTACGGAGACACATCCTCAGCCTCACTTCA
GTCGAACTTCATCTCCAGTTAAGTCATCTTTGTTCCTTGCACCCTCTGCCCTTAAGTTGTCTACACCATCTTCTTTATCTTCCAGTCAGGAGATACTAAA
AGATGTAGCTGAAATGAAAGAGGACCTAATGCGGATGACCGCAATACTACAGACAGATGTGCCTGAGGAGAAGCCATTCCAACCTGAACTCCCAAAGGAA
GGGAGAATAGATGATGAAGAACCTTTCAAAATTGTAGAGAAAGTAAAGGAAGACTTAGTGAAAGTTAGTGAAATCCTTAAAAAGGATGTATGTGTAGATA
ATAAAGGATCACCCAAATCACCAAAGAGTGACAAAGGACACTCTCCTGAAGATGACTGGATAGAATTTAGTTCGGAAGAAATCCGGGAAGCCAGACAACA
AGCTGCTGCGAGCCAGTCTCCATCTCTGCCAGAGAGAGTGCAAGTAAAAGCAAAAGCCGCCTCCGAAAAGGATTATAACTTGACCAAAGTTATTGATTAC
CTAACAAATGATATTGGGAGTAGTTCACTGACAAACTTAAAATACAAGTTTGAGGATGCAAAGAAGGATGGTGAGGAGAGACAGAAAAGAGTTTTAAAAC
CAGCAATTGCTTTGCAGGAACACAAACTCAAAATGCCTCCAGCCTCCATGAGGACTTCCACCTCTGAGAAAGAATTGTGTAAAATGGCTGATTCCTTTTT
TGGAACAGATACTATTTTAGAGTCTCCTGATGACTTTTCTCAACACGACCAAGATAAAAGTCCCTTGTCTGACAGTGGCTTTGAAACAAGAAGTGAAAAG
ACACCTTCAGCCCCACAAAGCGCTGAAAGCACTGGTCCTAAACCACTTTTTCATGAAGTTCCCATCCCTCCTGTCATTACAGAAACAAGAACTGAAGTGG
TTCATGTTATCAGGAGCTATGATCCCTCAGCTGGGGATGTTCCCCAGACCCAACCAGAGGAGCCTGTGTCACCTAAACCTTCACCTACTTTTATGGAATT
GGAACCAAAGCCCACCACCTCTAGTATTAAAGAAAAGGTTAAAGCATTTCAAATGAAAGCCAGTAGTGAAGAAGATGACCACAATCGGGTTTTAAGCAAA
GGCATGCGTGTTAAAGAAGAGACTCACATAACCACAACCACCAGAATGGTTTATCATTCTCCACCAGGCGGTGAAGGTGCATCTGAAAGAATTGAAGAAA
CCATGTCAGTCCATGACATCATGAAGGCCTTTCAGTCCGGGCGGGATCCTTCCAAAGAACTGGCAGGTCTGTTTGAACATAAGTCGGCAGTGTCTCCAGA
TGTTCACAAGTCTGCTGCTGAAACCTCAGCCCAGCATGCAGAGAAGGACAACCAAATGAAACCCAAACTGGAGCGTATAATAGAAGTCCACATCGAAAAA
GGTAACCAAGCTGAGCCCACTGAAGTCATTATTAGAGAAACCAAAAAGCATCCAGAAAAAGAAATGTATGTATATCAGAAAGACTTATCCCGGGGAGATA
TTAACCTAAAAGATTTTCTGCCAGAAAAACACGATGCTTTTCCTTGTTCAGAGGAACAGGGTCAGCAAGAAGAAGAAGAACTTACTGCTGAAGAGTCATT
GCCTTCTTATCTGGAGTCTTCCAGAGTAAACACTCCTGTGTCCCAAGAAGAAGATAGCCGCCCTAGTTCTGCTCAACTCATATCTGATGACTCTTATAAA
ACATTGAAGCTTTTGAGTCAACACTCAATAGAATACCATGACGATGAGTTGTCAGAACTAAGAGGGGAGTCTTACAGGTTTGCTGAGAAAATGCTTCTGT
CAGAAAAGCTAGATGTGTCTCATTCTGATACTGAGGAATCGGTTACAGACCATGCAGGACCCCCTAGCTCAGAGTTACAGGGGTCTGATAAGCGGTCCAG
AGAAAAAATAGCCACTGCCCCCAAAAAAGAAATTCTCTCCAAAATCTATAAAGATGTTTCTGAAAATGGTGTAGGTAAAGTGTCTAAAGATGAGCATTTT
GATAAAGTGACAGTGTTGCACTATTCTGGCAATGTTAGTAGTCCAAAACATGCCATGTGGATGCGCTTTACTGAGGACAGATTAGACAGAGGTAGAGAGA
AGTTGATATATGAAGATAGGGTGGACAGGACTGTGAAGGAGGCTGAAGAAAAACTGACTGAAGTGTCACAGTTTTTTCGTGACAAAACTGAAAAGCTAAA
TGATGAACTGCAGTCCCCAGAGAAAAAGGCACGCCCTAAAAATGGCAAAGAATATTCTTCTCAAAGCCCTACCAGTAGCAGCCCTGAGAAAGTGCTACTG
ACAGAACTGCTGGCATCCAATGATGAGTGGGTTAAGGCAAGACAGCATGGCCCTGATGGACAAGGCTTCCCCAAGGCCGAGGAGAAGGCACCCAGTCTGC
CCAGCAGCCCAGAGAAGATGGTTCTCTCCCAACAGACTGAGGACAGCAAGTCCACAGTGGAAGCCAAAGGAAGTATTTCACAGAGCAAAGCACCAGATGG
GCCCCAGTCTGGATTCCAGCTCAAACAATCTAAACTCAGTTCCATTAGATTAAAATTTGAACAAGGCACACACGCAAAAAGTAAGGACATGTCTCAAGAA
GACAGAAAGTCAGATGGCCAGTCCAGAATCCCAGTTAAAAAAATACAGGAGAGCAAGCTACCCGTCTACCAAGTTTTTGCTAGAGAAAAACAGCAGAAGG
CCATAGACCTCCCAGATGAAAGTGTATCTGTGCAAAAAGATTTTATGGTATTAAAAACCAAAGATGAGCATGCCCAAAGCAACGAAATTGTTGTAAATGA
TTCTGGCTCTGATAATGTGAAAAAACAGAGAACTGAAATGTCAAGTAAAGCAATGCCTGACTCTTTTTCTGAGCAGCAGGCTAAAGACTTGGCATGTCAT
ATAACCTCAGATTTAGCAACTAGGGGACCATGGGACAAAAAGGTCTTTAGAACATGGGAGAGTTCGGGAGCCACTAACAATAAGTCTCAGAAAGAAAAAC
TTTCGCATGTACTTGTTCATGATGTAAGAGAGAATCACATTGGTCACCCTGAGAGTAAAAGTGTTGATCAAAAGAATGAATTTATGTCTGTGACTGAGAG
AGAACGCAAATTGTTAACAAACGGCTCTCTCTCAGAAATTAAAGAAATGACTGTAAAATCTCCCTCCAAAAAAGTCTTATATAGGGAATATGTTGTGAAA
GAAGGGGACCATCCAGGCGGATTGCTTGATCAGCCTTCCAGGAGGAGCGAGAGCTCAGCAGTGTCACACATTCCCGTCAGAGTTGCTGATGAGAGGAGAA
TGCTGTCTTCTAATATTCCCGATGGTTTTTGTGAACAGTCGGCATTTCCAAAACATGAACTATCACAAAAATTGTCCCAGTCAAGCATGAGTAAAGAGAC
AGTTGAGACACAGCACTTTAATTCTATAGAAGATGAAAAAGTTACCTATTCAGAAATCAGCAAAGTTTCCAAACACCAGAGTTATGTAGGTTTATGCCCA
CCTCTCGAGGAAACCGAAACCTCCCCCACCAAATCTCCTGATTCTTTAGAGTTTAGCCCAGGAAAGGAATCTCCCTCTAGTGATGTATTCGACCACAGTC
CCATTGATGGATTGGAAAAACTCGCACCACTAGCCCAGACAGAGGGAGGGAAAGAGATAAAAACTTTACCCGTTTATGTCAGTTTTGTACAAGTGGGGAA
GCAATATGAAAAGGAGATACAACAAGGAGGTGTAAAAAAAATCATAAGTCAGGAATGTAAGACAGTACAAGAAACCAGGGGGACCTTTTATACAACTAGA
CAGCAAAAGCAACCTCCTTCTCCCCAAGGTAGTCCAGAAGATGATACTCTAGAGCAAGTATCCTTTCTAGACAGCTCTGGGAAAAGCCCTTTAACCCCAG
AAACACCCAGTTCAGAGGAAGTGAGTTATGAATTTACATCTAAGACACCTGACTCGCTCATAGCTTATATACCAGGCAAACCCAGCCCAATTCCCGAGGT
TTCTGAGGAGTCAGAGGAGGAGGAACAGGCCAAGTCAACCTCCCTTAAGCAGACTACAGTGGAGGAAACAGCAGTTGAGCGTGAAATGCCTAATGACGTG
AGCAAAGACTCTAACCAAAGACCCAAAAATAACAGAGTTGCCTATATTGAATTTCCCCCTCCTCCACCACTGGATGCGGACCAGATTGAGTCAGATAAGA
AGCATCATTATCTCCCAGAAAAAGAGGTTGACATGATTGAAGTCAATCTGCAAGATGAGCATGACAAGTACCAGCTGGCTGAACCTGTCATTAGAGTGCA
GCCACCTTCACCAGTTCCTCCCGGGGCAGACGTCAGTGATTCAAGCGATGACGAATCTATTTATCAGCCAGTCCCAGTTAAAAAATATACCTTCAAATTA
AAGGAAGTGGACGATGAACAAAAAGAAAAACCCAAAGCTTCTGCTGAAAAGGCTTCCAACCAGAAAGAACTGGAAAGTAATGGATCTGGAAAAGATAATG
AATTTGGCCTTGGCCTTGATTCACCTCAGAATGAAATTGCCCAGAATGGGAACAACGACCAGTCCATCACAGAGTGTTCCATTGCCACCACAGCAGAGTT
TTCTCATGACACGGATGCCACAGAGATCGACTCTCTGGATGGCTATGACCTGCAAGATGAAGATGATGGCTTGACAGAGAGTGATTCTAAACTCCCAATT
CAAGCCATGGAAATTAAGAAAGATATCTGGAACACAGAGGGCATTCTGAAGCCAGCTGACCGCTCTTTTAGCCAAAGTAAACTTGAAGTTATCGAGGAGG
AGGGAAAGGTGGGACCAGATGAGGACAAGCCACCTTCTAAAAGTTCTTCATCTGAAAAGACTCCTGATAAGACTGATCAGAAGTCAGGGGCCCAGTTCTT
CACACTGGAAGGCAGACATCCTGACAGATCAGTGTTTCCTGATACTTACTTCAGTTACAAAGTAGATGAAGAATTTGCCACTCCTTTTAAAACAGTAGCT
ACCAAAGGTCTAGATTTTGACCCTTGGTCTAATAACCGAGGGGATGATGAAGTTTTTGACAGTAAATCACGGGAAGATGAAACTAAGCCATTTGGGCTGG
CGGTAGAAGACCGCTCTCCAGCAACAACCCCTGATACAACGCCAGCCAGAACGCCAACTGATGAAAGTACCCCAACTAGTGAGCCTAACCCCTTCCCATT
TCATGAAGGAAAAATGTTTGAGATGACTCGCAGTGGTGCAATTGACATGAGCAAGAGGGATTTTGTTGAAGAGAGGCTCCAATTTTTCCAGATTGGTGAG
CATACTTCTGAAGGGAAGTCAGGGGACCAGGGGGAAGGGGATAAAAGTATGGTCACTGCCACACCACAGCCACAGTCAGGGGACACCACTGTAGAAACCA
ATCTAGAGAGAAATGTAGAGACACCTACAGTGGAACCTAACCCCAGCATCCCGACCAGCGGAGAGTGTCAGGAAGGCACATCCAGTAGTGGCTCCCTGGA
GAAATCAGCAGCAGCCACTAACACCTCTAAAGTTGACCCCAAGTTGCGCACGCCTATAAAAATGGGAATTTCTGCATCCACCATGACCATGAAGAAAGAA
GGCCCTGGAGAAATAACAGATAAGATAGAAGCGGTGATGACCAGTTGTCAGGGATTAGAAAATGAAACTATAACAATGATTTCAAATACAGCCAATAGCC
AGATGGGCGTTAGGCCCCATGAAAAACATGATTTTCAAAAAGATAACTTTAATAACAACAACAATTTGGATTCTTCCACTATACAGACAGATAACATTAT
GAGTAATATAGTTCTGACAGAACATTCTGCACCCACTTGTACCACAGAGAAAGATAACCCAGTGAAAGTCTCATCAGGAAAAAAGACAGGGGTACTACAA
GGACACTGTGTAAGAGATAAGCAGAAAGTTCTTGGAGAACAGCAAAAAACAAAGGAATTGATAGGGATTAGGCAAAAATCCAAACTTCCCATAAAGGCCA
CTTCACCAAAAGATACCTTCCCACCGAACCATATGTCAAACACTAAAGCAAGTAAAATGAAGCAGGTTAGTCAATCCGAGAAAACCAAAGCCCTTACTAC
TTCTTCATGTGTAGATGTAAAGTCCAGAATTCCAGTGAAAAACACACACAGGGATAACATAATTGCAGTTAGAAAAGCATGTGCCACACAAAAGCAAGGG
CAGCCAGAGAAAGGCAAGGCCAAACAGCTTCCATCCAAGTTGCCAGTAAAGGTAAGATCCACCTGTGTCACTACCACCACCACCACTGCCACCACCACCA
CCACTACCACCACTACCACCACCACCAGCTGCACAGTTAAAGTTAGGAAAAGTCAGCTCAAGGAAGTATGTAAACATTCCATTGAATATTTTAAGGGAAT
TAGTGGTGAGACCTTAAAGCTTGTGGACCGCCTCTCTGAAGAAGAAAAAAAGATGCAGTCCGAGTTGTCCGATGAGGAAGAAAGTACCTCAAGAAACACG
TCGTTGTCCGAGACTTCCCGGGGTGGCCAGCCTTCGGTTACAACGAAGTCTGCTAGAGATAAGAAAACAGAGGCAGCACCTTTAAAATCAAAGAGTGAAA
AGGCCGGCAGTGAGAAAAGGAGCAGTAGAAGGACTGGTCCACAGAGTCCATGTGAACGGACAGATATCAGGATGGCAATAGTAGCCGATCACCTGGGACT
TAGTTGGACAGAACTGGCAAGGGAACTGAATTTTTCAGTGGATGAAATCAATCAAATACGTGTGGAAAATCCAAATTCTTTAATTTCTCAGAGCTTCATG
TTATTAAAAAAATGGGTTACCAGAGACGGAAAAAATGCCACAACTGATGCCTTAACTTCGGTCTTGACAAAAATTAATCGAATAGATATAGTGACACTGC
TAGAAGGACCAATATTTGATTATGGAAATATTTCAGGCACCAGAAGTTTTGCAGATGAGAACAATGTTTTCCATGACCCTGTTGATGGTTGGCAGAATGA
GACATCAAGTGGAAACCTAGAGTCCTGCGCTCAAGCTCGAAGAGTAACTGGTGGGTTACTAGATCGACTGGATGACAGCCCTGACCAGTGTAGAGATTCC
ATTACCTCATATCTCAAAGGAGAAGCTGGCAAATTTGAAGCAAATGGAAGCCATACAGAAATCACTCCAGAAGCAAAGACAAAATCTTACTTTCCAGAAT
CCCAAAATGATGTAGGAAAACAGAGTACCAAGGAAACTCTGAAACCAAAAATACATGGATCTGGTCATGTTGAAGAACCAGCATCACCACTAGCAGCATA
TCAGAAATCTCTAGAAGAAACCAGCAAGCTTATAATAGAAGAGACTAAACCCTGTGTGCCTGTCAGTATGAAAAAGATGAGTAGGACTTCTCCAGCAGAT
GGCAAGCCAAGGCTTAGCCTCCATGAAGAAGAGGGGTCCAGTGGGTCTGAGCAAAAGCAGGGAGAAGGTTTTAAGGTGAAAACGAAGAAAGAAATCCGGC
ATGTGGAAAAGAAGAGCCACTCGTAACAGCGAACGGTCAGTCAAGGATCATAAGTTTTTACTGCCAGTATTGAGAAATTCGTGGAAGAAATGTCAGCAGG
AAGTAAAAATTCACCGAGAAGTGTGTGTGTGTTCGCTGCTTCCACACATTAATGGCATGATTTTTTTTATGCAAAAAGAAAAGAAAAGAAAACCACCCAC
ATTTTAATTTAGCATGAGCCAATTTACAGAGCATGGAAATCACTTTCATTTCCGGATTGGCGCGTGTGCAATTAGCAATGCAGTGTATATACAAGAAGCC
ATGCTGTTAACAGTTTATCTCAAGTAATTTGGTGTCATTTACAAAAGGAAGAAATTCCTGCCATCAGAAGGGACAGAAGGAGATGGAATGATCAAATCAC
AGAGAAACACTAAAATTACTAAATCTACAACAGCTCGCCTTATTTTTCTTGGACCCAAACTGTCAGGGTATAAACACTATTTGTTTCTTTTTTAAAACAT
CGATAGTTTTGCTGTAAATAATAACACTGTATAAATTCTAACAGAAAAATAGAATAAAATGTTGATAAGGCACTGCCTCTTAGAACACAAACAGAATATT
GCAAATGCATTTAACAAATAGGGGTCTCAAGTGACTTCACCCTAGAAGAGGAGGGAGGGATTCTGGGTGGGGGTGACTCTTCACTGATTCTTGTATATTA
GCAATTATAATGTTTGTATATGCAAAACTGCTAGCTTGATTTTAAAAAAAAACAAATCTTTAAAATCTGCTGCAAATTTAAATAATTCCCAAAATGAGGA
ATTCTGTAGTTCTGTGAAAAATTTTTTTCTTCAGAATACTAATATTTTGATGCATGTGTATCACCTTATTTTGATTAAATCTTTTCCAATTTTGCAAACA
CTACAGTATACTGCAACACAAAAGATTTTATCTGTAAACACAAAGCCCTTCATCTAATATTTGTTGCTATTGCCAATTTTTCAATGAAATGACCTAAAAA
CAACAAAAAAAAATAACCTATACGGTAGTTGCTTTAGGGGGTGGGGGGATGCTATCTGTTAGTGCTTAAAAGGGGGTAAATGCTTGCCGCTTTAGAGGTG
GATGGTGCTCATAAAAGGCCCCAGTCGGGGGTATTTAAAAAGGACTGAACAGAAATCCTTAGCTAGTAGAATGGCAGCACGCTGTAAAATTATTACTGTA
TTGTGTACTGGCTATAAGATGTAGACACCTTTCAGTAAGCCAATCATTTGTAACCATTCTAGCAGTGTCATATTAGGTTAATAAGGCTGCTGTGTTTTAA
AGGGCATTTTTATTTGGGTTTTGGTGAAATTCTTTAATTTGTTGATTATATTCACATAAAATCAGCATTCATTGACACATAGCTCTAATGACATATGTAT
GAAAAACCATACACTGGATGACCTAGTCGATTATTTAAGCATAAAATAAATTGTGTTAAACTCTTCACCTA
  • refseq_ANK3.F1 (forward primer)
  • refseq_ANK3.R1 (reverse primer)
  • Single exon skipping

Frame 0

GHHHLGF*KLQLLQHLCIVNIFLLLVKAFSLVI
GMLL*A*LEVPEDITFYKEAVCA*EDLFKCIMAH
AASQLKKNRDLEINAEEEPEKKRKHRKRSRDRK
KKSDANASYLRAARAGHLEKALDYIKNGVDINI
CNQNGLNALHLASKEGHVEVVSELLQREANVDAA
TKKGNTALHIASLAGQAEVVKVLVTNGANVNAQ
SQNGFTPLYMAAQENHLEVVKFLLDNGASQSLA
TEDGFTPLAVALQQGHDQVVSLLLENDTKGKVRL
PALHIAARKDDTKAAALLLQNDNNADVESKSGF
TPLHIAAHYGNINVATLLLNRAAAVDFTARNDI
TPLHVASKRGNANMVKLLLDRGAKIDAKTRDGLT
PLHCGARSGHEQVVEMLLDRAAPILSKTKNGLS
PLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLT
ALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTP
LHIACKKNRIKVMELLLKHGASIQAVTESGLTP
IHVAAFMGHVNIVSQLMHHGASPNTTNVRGETA
LHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPL
HISARLGKADIVQQLLQQGASPNAATTSGYTPL
HLSAREGHEDVAAFLLDHGASLSITTKKGFTPL
HVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLH
VAAHYDNQKVALLLLDQGASPHAAAKNGYTPLH
IAAKKNQMDIATTLLEYGADANAVTRQGIASVH
LAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLHL
AAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHV
GCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQ
AAQQGHTHIINVLLQNNASPNELTVNGNTALGIA
RRLGYISVVDTLKIVTEETMTTTTVTEKHKMNV
PETMNEVLDMSDDEVRKANAPEMLSDGEYISDV
EEGEDAMTGDTDKYLGPQDLKELGDDSLPAEGYM
GFSLGARSASLRSFSSDRSYTLNRSSYARDSMM
IEELLVPSKEQHLTFTREFDSDSLRHYSWAADT
LDNVNLVSSPIHSGFLVSFMVDARGGSMRGSRHH
GMRIIIPPRKCTAPTRITCRLVKRHKLANPPPM
VEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGS
MRGKERELIVLRSENGETWKEHQFDSKNEDLTEL
LNGMDEELDSPEELGKKRICRIITKDFPQYFAV
VSRIKQESNQIGPEGGILSSTTVPLVQASFPEG
ALTKRIRVGLQAQPVPDEIVKKILGNKATFSPIV
TVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKG
DTTPNLRLLCSITGGTSPAQWEDITGTTPLTFI
KDCVSFTTNVSARFWLADCHQVLETVGLATQLYR
ELICVPYMAKFVVFAKMNDPVESSLRCFCMTDD
KVDKTLEQQENFEEVARSKDIEVLEGKPIYVDC
YGNLAPLTKGGQQLVFNFYSFKENRLPFSIKIRD
TSQEPCGRLSFLKEPKTTKGLPQTAVCNLNITL
PAHKKETESDQDDEIEKTDRRQSFASLALRKRY
SYLTEPGMIERSTGATRSLPTTYSYKPFFSTRPY
QSWTTAPITVPGPAKSGFTSLSSSSSNTPSASP
LKSIWSVSTPSPIKSTLGASTTSSVKSISDVAS
PIRSFRTMSSPIKTVVSQSPYNIQVSSGTLARAP
AVTEATPLKGLASNSTFSSRTSPVTTAGSLLER
SSITMTPPASPKSNINMYSSSLPFKSIITSAAP
LISSPLKSVVSPVKSAVDVISSAKITMASSLSSP
VKQMPGHAEVALVNGSISPLKYPSSSTLINGCK
ATATLQEKISSATNSVSSVVSAATDTVEKVFST
TTAMPFSPLRSYVSAAPSAFQSLRTPSASALYTS
LGSSISATTSSVTSSIITVPVYSVVNVLPEPAL
KKLPDSNSFTKSAAALLSPIKTLTTETHPQPHF
SRTSSPVKSSLFLAPSALKLSTPSSLSSSQEILK
DVAEMKEDLMRMTAILQTDVPEEKPFQPELPKE
GRIDDEEPFKIVEKVKEDLVKVSEILKKDVCVD
NKGSPKSPKSDKGHSPEDDWIEFSSEEIREARQQ
AAASQSPSLPERVQVKAKAASEKDYNLTKVIDY
LTNDIGSSSLTNLKYKFEDAKKDGEERQKRVLK
PAIALQEHKLKMPPASMRTSTSEKELCKMADSFF
GTDTILESPDDFSQHDQDKSPLSDSGFETRSEK
TPSAPQSAESTGPKPLFHEVPIPPVITETRTEV
VHVIRSYDPSAGDVPQTQPEEPVSPKPSPTFMEL
EPKPTTSSIKEKVKAFQMKASSEEDDHNRVLSK
GMRVKEETHITTTTRMVYHSPPGGEGASERIEE
TMSVHDIMKAFQSGRDPSKELAGLFEHKSAVSPD
VHKSAAETSAQHAEKDNQMKPKLERIIEVHIEK
GNQAEPTEVIIRETKKHPEKEMYVYQKDLSRGD
INLKDFLPEKHDAFPCSEEQGQQEEEELTAEESL
PSYLESSRVNTPVSQEEDSRPSSAQLISDDSYK
TLKLLSQHSIEYHDDELSELRGESYRFAEKMLL
SEKLDVSHSDTEESVTDHAGPPSSELQGSDKRSR
EKIATAPKKEILSKIYKDVSENGVGKVSKDEHF
DKVTVLHYSGNVSSPKHAMWMRFTEDRLDRGRE
KLIYEDRVDRTVKEAEEKLTEVSQFFRDKTEKLN
DELQSPEKKARPKNGKEYSSQSPTSSSPEKVLL
TELLASNDEWVKARQHGPDGQGFPKAEEKAPSL
PSSPEKMVLSQQTEDSKSTVEAKGSISQSKAPDG
PQSGFQLKQSKLSSIRLKFEQGTHAKSKDMSQE
DRKSDGQSRIPVKKIQESKLPVYQVFAREKQQK
AIDLPDESVSVQKDFMVLKTKDEHAQSNEIVVND
SGSDNVKKQRTEMSSKAMPDSFSEQQAKDLACH
ITSDLATRGPWDKKVFRTWESSGATNNKSQKEK
LSHVLVHDVRENHIGHPESKSVDQKNEFMSVTER
ERKLLTNGSLSEIKEMTVKSPSKKVLYREYVVK
EGDHPGGLLDQPSRRSESSAVSHIPVRVADERR
MLSSNIPDGFCEQSAFPKHELSQKLSQSSMSKET
VETQHFNSIEDEKVTYSEISKVSKHQSYVGLCP
PLEETETSPTKSPDSLEFSPGKESPSSDVFDHS
PIDGLEKLAPLAQTEGGKEIKTLPVYVSFVQVGK
QYEKEIQQGGVKKIISQECKTVQETRGTFYTTR
QQKQPPSPQGSPEDDTLEQVSFLDSSGKSPLTP
ETPSSEEVSYEFTSKTPDSLIAYIPGKPSPIPEV
SEESEEEEQAKSTSLKQTTVEETAVEREMPNDV
SKDSNQRPKNNRVAYIEFPPPPPLDADQIESDK
KHHYLPEKEVDMIEVNLQDEHDKYQLAEPVIRVQ
PPSPVPPGADVSDSSDDESIYQPVPVKKYTFKL
KEVDDEQKEKPKASAEKASNQKELESNGSGKDN
EFGLGLDSPQNEIAQNGNNDQSITECSIATTAEF
SHDTDATEIDSLDGYDLQDEDDGLTESDSKLPI
QAMEIKKDIWNTEGILKPADRSFSQSKLEVIEE
EGKVGPDEDKPPSKSSSSEKTPDKTDQKSGAQFF
TLEGRHPDRSVFPDTYFSYKVDEEFATPFKTVA
TKGLDFDPWSNNRGDDEVFDSKSREDETKPFGL
AVEDRSPATTPDTTPARTPTDESTPTSEPNPFPF
HEGKMFEMTRSGAIDMSKRDFVEERLQFFQIGE
HTSEGKSGDQGEGDKSMVTATPQPQSGDTTVET
NLERNVETPTVEPNPSIPTSGECQEGTSSSGSLE
KSAAATNTSKVDPKLRTPIKMGISASTMTMKKE
GPGEITDKIEAVMTSCQGLENETITMISNTANS
QMGVRPHEKHDFQKDNFNNNNNLDSSTIQTDNIM
SNIVLTEHSAPTCTTEKDNPVKVSSGKKTGVLQ
GHCVRDKQKVLGEQQKTKELIGIRQKSKLPIKA
TSPKDTFPPNHMSNTKASKMKQVSQSEKTKALTT
SSCVDVKSRIPVKNTHRDNIIAVRKACATQKQG
QPEKGKAKQLPSKLPVKVRSTCVTTTTTTATTT
TTTTTTTTTSCTVKVRKSQLKEVCKHSIEYFKGI
SGETLKLVDRLSEEEKKMQSELSDEEESTSRNT
SLSETSRGGQPSVTTKSARDKKTEAAPLKSKSE
KAGSEKRSSRRTGPQSPCERTDIRMAIVADHLGL
SWTELARELNFSVDEINQIRVENPNSLISQSFM
LLKKWVTRDGKNATTDALTSVLTKINRIDIVTL
LEGPIFDYGNISGTRSFADENNVFHDPVDGWQNE
TSSGNLESCAQARRVTGGLLDRLDDSPDQCRDS
ITSYLKGEAGKFEANGSHTEITPEAKTKSYFPE
SQNDVGKQSTKETLKPKIHGSGHVEEPASPLAAY
QKSLEETSKLIIEETKPCVPVSMKKMSRTSPAD
GKPRLSLHEEEGSSGSEQKQGEGFKVKTKKEIR
HVEKKSHS*QRTVSQGS*VFTASIEKFVEEMSAG
SKNSPRSVCVFAASTH*WHDFFYAKRKEKKTTH
ILI*HEPIYRAWKSLSFPDWRVCN*QCSVYTRS
HAVNSLSQVIWCHLQKEEIPAIRRDRRRWNDQIT
EKH*NY*IYNSSPYFSWTQTVRV*TLFVSFLKH
R*FCCK**HCINSNRKIE*NVDKALPLRTQTEY
CKCI*QIGVSSDFTLEEEGGILGGGDSSLILVY*
QL*CLYMQNC*LDFKKKQIFKICCKFK*FPK*G
IL*FCEKFFSSEY*YFDACVSPYFD*IFSNFAN
TTVYCNTKDFICKHKALHLIFVAIANFSMK*PKN
NKKK*PIR*LL*GVGGCYLLVLKRG*MLAALEV
DGAHKRPQSGVFKKD*TEILS**NGSTL*NYYC
IVYWL*DVDTFQ*ANHL*PF*QCHIRLIRLLCFK
GHFYLGFGEIL*FVDYIHIKSAFIDT*L**HMY
EKPYTG*PSRLFKHKINCVKLFT

Frame 1

DTIIWVFKSFSFSSIFAL*ISSCF*SKLSL**L
ECCCKPD*RCLRISPFTRKPCVLERIFLNALWL
MQPHN*RKTGI*KSMLKKSLRKKGNTANGPGIGR
KSLMPMQVT*EQLELDTLKRPSTT*KMELTSTF
AIRMG*TLSTLLPKKAM*RLFLSCCREKPMWMQ
LQRKETQHCTSHLWLGKQRW*KSWLQMEPMSMHN
LRMVSRHCIWQPRKITWKLSSFFLTMVQARA*P
QRMASHHWQWLCNKVTTKSFRSC*RMTPKEKCV
SQLFISRPEKTTRKPPPCCCRMTTMQMWNQRVAS
LRST*LLTMEISM*PRCC*TERLLWISPQGMTS
LLYMLHQKEEMQIW*NYCSIEELKSMPKPGMV*
HHCTVEQGVATSRW*KCCLIELPPFFQKPRMDYL
HCTWPHKGII*TASSFSSSIMYPWMMSPMTT*L
PYTWLPTVAITKLPRFSWIRKLTPMPKP*MALP
LFILPARRIELK*WNSF*NTVHPSKL*PSRALPQ
SMLLPSWGM*ILYHN*CIMEPHQTPPM*EEKQH
CTWQLAPAKLKLCGIWYKTELR*KLKLRMTKHH
STFQPDWGKQT*YNSCCSKGHLQMQPQLLGTPHF
TFPPERGMRMWPRSFWIMERLYL*QQRKDLLLF
MWQQNMESLKSPISCYRKVHLQMLLGRAG*HHC
M*LHITIIRKWPFCFWTKEPHLTQPQRMVIRHCT
SLPKRTRWT*RQLCWNMVLMPTQLPGKELLPSI
SQLRKGTWTWCRCSSVEMRM*T*AIRAA*PHSI
WLLKKIE*MWQKSS*TKGLMWTPRQRWDTHHCMW
AATMEISRLLISCSSILQKLMPKQRMGIRHYIK
QHSRGIRI**MSYFRTTPPPMNSL*MGILPLAL
PGASATSQ*WTP*R**PKRP*PQLLSQRSTK*MF
QKR*MKFLICLMMKFVKPMPLKCSVMANISQML
KKVKMQ*PGTQTNILGHRTLRNWVMIPCLQRVT
WALVSERVLPASAPSVRIGLTP*TEAPMHGTA**
LKNSLCHPKSSI*HSQGNLIQILLDITAGLQTP
*TMSILFQAPFILGFWLALWWTREGAP*EEAVI
TG*ESSFLHASVRPPLESPAVW*RDINWPTHPPW
WKERD*PVGW*KWVLQGHNF*ALS*WKSLTLGP
*EEKRENSLFFEVKMVKLGRSISLTAKMKI*PS
YLMAWMKNLIAQKS*GKSVSAGLSRKISPSILQW
FPGLSRKATRLVLKVEF*AAPQCPLFKHLSQRV
P*LKEFEWASRPSLFQMKL*KRSLETKQLLAQL
SLWNQEDGNSINQSQ*PFRCPRPQEKVYPMDTKG
TLHPICVFSVALQGALRLLSGKTSQEQLL*RL*
KIVSPLQPMFQPDFGLQTAIKF*KLWG*PRNCT
EN*YVFHIWPSLLFLPK*MIP*NLPCDVSA*QMT
KWTKL*SNKRILRKSQEAKILRFWKENLFMLIV
MEIWPHLPKEDSNLFLTFILSKKIDCHFPSRLE
TPAKSPVVVCLF*KNQRQQKDCLKQRFAT*ISLC
QHIKRRQSQIKMMRLRKQIDDRASHP*LYVSAT
AT*LSLE*LNGVQEQQDPSPPLTHTSHSFLQDH
TSPGQQLRLQCLGQPSQASLPYQVLPLIRHQLLR
*NQYGLFRHLLQSNPH*ARQLHLQLNPLVTWHL
QLDPFGQCLRR*KLWCHNLHTISKFPLVPWLEL
QQSRKLRP*KGWHPILRFPLEPLQ*LQQGLFWRG
HQLL*HPLPPPNQTLICIPQVCHLSQLLHQQHR
*YLHL*SQWCLQLNQQLMSFHQPKLQWHLLSHH
L*SRCLDMQR*H*SMDLFPL*NIHHPQL*LMDAK
PLPRYRKKFLLLQTL*ALWSVQPLTQLRKCFLP
RLQCHFPHSGHMFLQHHQLFSL*ELLPQVHSIH
PLGRQYLQLPHL*LHQL*QCQYTL*SMFCQNQH*
RNFQTLIHLQNQQQPCCHPLKH*LRRHILSLTS
VELHLQLSHLCSLHPLPLSCLHHLLYLPVRRY*
KM*LK*KRT*CG*PQYYRQMCLRRSHSNLNSQRK
GE*MMKNLSKL*RK*RKT**KLVKSLKRMYV*I
IKDHPNHQRVTKDTLLKMTG*NLVRKKSGKPDN
KLLRASLHLCQRECK*KQKPPPKRIIT*PKLLIT
*QMILGVVH*QT*NTSLRMQRRMVRRDRKEF*N
QQLLCRNTNSKCLQPP*GLPPLRKNCVKWLIPF
LEQILF*SLLMTFLNTTKIKVPCLTVALKQEVKR
HLQPHKALKALVLNHFFMKFPSLLSLQKQELKW
FMLSGAMIPQLGMFPRPNQRSLCHLNLHLLLWN
WNQSPPPLVLKKRLKHFK*KPVVKKMTTIGF*AK
ACVLKKRLT*PQPPEWFIILHQAVKVHLKELKK
PCQSMTS*RPFSPGGILPKNWQVCLNISRQCLQ
MFTSLLLKPQPSMQRRTTK*NPNWSV**KSTSKK
VTKLSPLKSLLEKPKSIQKKKCMYIRKTYPGEI
LT*KIFCQKNTMLFLVQRNRVSKKKKNLLLKSH
CLLIWSLPE*TLLCPKKKIAALVLLNSYLMTLIK
H*SF*VNTQ*NTMTMSCQN*EGSLTGLLRKCFC
QKS*MCLILILRNRLQTMQDPLAQSYRGLISGP
EKK*PLPPKKKFSPKSIKMFLKMV*VKCLKMSIL
IK*QCCTILAMLVVQNMPCGCALLRTD*TEVER
S*YMKIGWTGL*RRLKKN*LKCHSFFVTKLKS*
MMNCSPQRKRHALKMAKNILLKALPVAALRKCY*
QNCWHPMMSGLRQDSMALMDKASPRPRRRHPVC
PAAQRRWFSPNRLRTASPQWKPKEVFHRAKHQM
GPSLDSSSNNLNSVPLD*NLNKAHTQKVRTCLKK
TESQMASPESQLKKYRRASYPSTKFLLEKNSRR
P*TSQMKVYLCKKILWY*KPKMSMPKATKLL*M
ILALIM*KNRELKCQVKQCLTLFLSSRLKTWHVI
*PQI*QLGDHGTKRSLEHGRVREPLTISLRKKN
FRMYLFMM*ERITLVTLRVKVLIKRMNLCL*LR
ENANC*QTALSQKLKK*L*NLPPKKSYIGNML*K
KGTIQADCLISLPGGARAQQCHTFPSELLMRGE
CCLLIFPMVFVNSRHFQNMNYHKNCPSQA*VKR
QLRHSTLIL*KMKKLPIQKSAKFPNTRVM*VYAH
LSRKPKPPPPNLLIL*SLAQERNLPLVMYSTTV
PLMDWKNSHH*PRQREGKR*KLYPFMSVLYKWG
SNMKRRYNKEV*KKS*VRNVRQYKKPGGPFIQLD
SKSNLLLPKVVQKMIL*SKYPF*TALGKAL*PQ
KHPVQRK*VMNLHLRHLTRS*LIYQANPAQFPR
FLRSQRRRNRPSQPPLSRLQWRKQQLSVKCLMT*
AKTLTKDPKITELPILNFPLLHHWMRTRLSQIR
SIIISQKKRLT*LKSICKMSMTSTSWLNLSLEC
SHLHQFLPGQTSVIQAMTNLFISQSQLKNIPSN*
RKWTMNKKKNPKLLLKRLPTRKNWKVMDLEKIM
NLALALIHLRMKLPRMGTTTSPSQSVPLPPQQS
FLMTRMPQRSTLWMAMTCKMKMMA*QRVILNSQF
KPWKLRKISGTQRAF*SQLTALLAKVNLKLSRR
RERWDQMRTSHLLKVLHLKRLLIRLIRSQGPSS
SHWKADILTDQCFLILTSVTK*MKNLPLLLKQ*L
PKV*ILTLGLITEGMMKFLTVNHGKMKLSHLGW
R*KTALQQQPLIQRQPERQLMKVPQLVSLTPSH
FMKEKCLR*LAVVQLT*ARGILLKRGSNFSRLVS
ILLKGSQGTRGKGIKVWSLPHHSHSQGTPL*KP
I*REM*RHLQWNLTPASRPAESVRKAHPVVAPW
RNQQQPLTPLKLTPSCARL*KWEFLHPP*P*RKK
ALEK*QIR*KR**PVVRD*KMKL*Q*FQIQPIA
RWALGPMKNMIFKKITLITTTIWILPLYRQITL
*VI*F*QNILHPLVPQRKITQ*KSHQEKRQGYYK
DTV*EISRKFLENSKKQRN**GLGKNPNFP*RP
LHQKIPSHRTICQTLKQVK*SRLVNPRKPKPLL
LLHV*M*SPEFQ*KTHTGIT*LQLEKHVPHKSKG
SQRKARPNSFHPSCQ*R*DPPVSLPPPPLPPPP
PLPPLPPPPAAQLKLGKVSSRKYVNIPLNILRE
LVVRP*SLWTASLKKKKRCSPSCPMRKKVPQETR
RCPRLPGVASLRLQRSLLEIRKQRQHL*NQRVK
RPAVRKGAVEGLVHRVHVNGQISGWQ**PITWD
LVGQNWQGN*IFQWMKSIKYVWKIQIL*FLRASC
Y*KNGLPETEKMPQLMP*LRS*QKLIE*I**HC
*KDQYLIMEIFQAPEVLQMRTMFSMTLLMVGRM
RHQVET*SPALKLEE*LVGY*IDWMTALTSVEIP
LPHISKEKLANLKQMEAIQKSLQKQRQNLTFQN
PKMM*ENRVPRKL*NQKYMDLVMLKNQHHH*QH
IRNL*KKPASL**KRLNPVCLSV*KR*VGLLQQM
ASQGLASMKKRGPVGLSKSREKVLR*KRRKKSG
MWKRRATRNSERSVKDHKFLLPVLRNSWKKCQQ
EVKIHREVCVCSLLPHINGMIFFMQKEKKRKPPT
F*FSMSQFTEHGNHFHFRIGACAISNAVYIQEA
MLLTVYLK*FGVIYKRKKFLPSEGTEGDGMIKS
QRNTKITKSTTARLIFLGPKLSGYKHYLFLF*NI
DSFAVNNNTV*ILTEK*NKMLIRHCLLEHKQNI
ANAFNK*GSQVTSP*KRREGFWVGVTLH*FLYI
SNYNVCICKTASLILKKNKSLKSAANLNNSQNEE
FCSSVKNFFLQNTNILMHVYHLILIKSFPILQT
LQYTATQKILSVNTKPFI*YLLLLPIFQ*NDLK
TTKKNNLYGSCFRGWGDAIC*CLKGGKCLPL*RW
MVLIKGPSRGYLKRTEQKSLASRMAARCKIITV
LCTGYKM*TPFSKPIICNHSSSVILG**GCCVL
KGIFIWVLVKFFNLLIIFT*NQHSLTHSSNDICM
KNHTLDDLVDYLSIK*IVLNSSP

Frame 2

TPSFGFLKASASPASLHCEYLPASSQSFLSSDW
NAAVSLIRGA*GYHLLQGSRVCLRGSF*MHYGS
CSLTIKEKQGFRNQC*RRA*EKKETPQTVPGSE
EKV*CQCKLLKSSSSWTP*KGPRLHKKWS*HQHL
QSEWVERSPPCFQRRPCRGCF*AAAERSQCGCS
YKERKHSIAHRIFGWASRGGKSLGYKWSQCQCT
ISEWFHAIVYGSPGKSPGSCQVSS*QWCKPEPSH
RGWLHTIGSGFATRSRPSRFAPARE*HQRKSAS
PSSSYRGPKRRHESRRPAAAE*QQCRCGIKEWL
HSAPHSCSLWKYQCSHVAVKPSGCCGFHRKE*HH
SFTCCIKKRKCKYGKTIARSRS*NRCQNQGWSD
TTALWSKEWPRAGGRNVA*SSCPHSFKNQEWII
SIAHGHTRGSFKLRPASPPA*CTRG*CHQ*LPDC
PTRGCPLWPLQSCQGSLG*ES*PQCQSPEWLYP
SSYCLQEESN*SNGTPSETRCIHPSCNRVGPYP
NPCCCLHGACKYCITTNASWSLTKHHQCERRNST
AHGSSLRPS*SCAVSGTRRSSGRS*S*G*PNTT
PHFSPTGESRHSTTAVAARGISKCSHNFWVHPT
SPFRPRGA*GCGRVPFGSWSVFIYNNKERIYSSS
CGSKIWKA*SRQSPATEKCISRCCWEERANTTA
CSCTLR*SESGPSAFGPRSLTSRSRKEWLYATA
HRCQKEPDGHSDNSAGIWC*CQRSYPARNCFRPS
RSSGRARGHGVAAPR*KCECEPEQ*ERPDPTPF
GCSRRSSECGRSPRKPRGSCGRPDKDGIHTTAC
GLPLWKYQDC*FPAPAFCKS*CQNKEWVYAITSS
STAGAYAYNKCLTSEQRLPQ*THCEWEYCPWHC
PAPRLHLSSGHPEDSDRRDHDHNYCHREAQNEC
SRNDE*SS*YV***SS*SQCP*NAQ*WRIYLRC*
RR*RCNDRGHRQISWATGP*GIG**FPACRGLH
GL*SRSAFCQPPLLQFG*VLHLEQKLLCTGQHD
D*RTPCAIQRAASNIHKGI*FRFS*TLQLGCRHL
RQCQSCFKPHSFWVSG*LYGGRERGLHERKPSS
RDENHHSSTQVYGPHSNHLPFGKET*TGQPTPH
GGRRGISQ*AGRNGSCRGTIFRPCHSGNPSLWVH
ERKRERTHCSSK*KW*NLEGASV*QQK*RFNRV
T*WHG*RT**PRRVREKAYLQDYHERFPPVFCS
GFPD*AGKQPDWS*RWNSEQHHSAPCSSIFPRGC
PN*KNSSGPPGPACSR*NCEKDPWKQSNF*PNC
HCGTKKTEIP*TNHNDHSGAPALRRRCIQWIQR
GHYTQSASSL*HYRGHFACSVGRHHRNNSFDVYK
RLCLLYNQCFSQILACRLPSSFRNCGVSHATVQ
RIDMCSIYGQVCCFCQNE*SRRIFLAMFLHDR*
QSGQNFRATREF*GSRKKQRY*GSGRKTYLC*LL
WKFGPTYQRRTATCF*LLFFQRK*TAIFHQD*R
HQPRALWSSVFSERTKDNKRTASNSGLQLKYHS
AST*KGDRVRSR**D*ENR*TTELRILSFT*ALQ
LLD*AWND*TEYRSNKIPPHHLLIQAILFYKTI
PVLDNSSDYSAWASQVRLHFLIKFFL*YAISFS
VKINMVCFDTFSNQIHIRRVNYIFS*IH**RGIS
N*ILSDNVFADKNCGVTISIQYPSFLWYPG*SS
SSHGSYALKRAGIQFYVFLSNLSSDYSRVSFGE
VINYYDTPCLPQIKH*YVFLKFAI*VNYYISSTA
NIFTFKVSGVSS*ISS*CHFISQNYNGIFSLIT
CEADAWTCRGSISQWIYFPSKISIILNFN*WMQ
SHCHVTGKNFFCYKLCELCGQCSH*HS*ESVFYH
DCNAIFPTQVICFCSTISFSVSKNSFRKCTLYI
PWVVNICNYLICNFINYNSASILCSQCFARTSI
KETSRL*FIYKISSSLAVTH*NIDYGDTSSASLQ
SNFISS*VIFVPCTLCP*VVYTIFFIFQSGDTK
RCS*NERGPNADDRNTTDRCA*GEAIPT*TPKG
RENR**RTFQNCRESKGRLSES**NP*KGCMCR*
*RITQITKE*QRTLS*R*LDRI*FGRNPGSQTT
SCCEPVSISARESASKSKSRLRKGL*LDQSY*L
PNK*YWE*FTDKLKIQV*GCKEGW*GETEKSFKT
SNCFAGTQTQNASSLHEDFHL*ERIV*NG*FLF
WNRYYFRVS**LFSTRPR*KSLV*QWL*NKK*K
DTFSPTKR*KHWS*TTFS*SSHPSCHYRNKN*SG
SCYQEL*SLSWGCSPDPTRGACVT*TFTYFYGI
GTKAHHL*Y*RKG*SISNESQ**RR*PQSGFKQ
RHAC*RRDSHNHNHQNGLSFSTRR*RCI*KN*RN
HVSP*HHEGLSVRAGSFQRTGRSV*T*VGSVSR
CSQVCC*NLSPACREGQPNETQTGAYNRSPHRK
R*PS*AH*SHY*RNQKASRKRNVCISERLIPGRY
*PKRFSARKTRCFSLFRGTGSARRRRTYC*RVI
AFLSGVFQSKHSCVPRRR*PP*FCSTHI**LL*
NIEAFESTLNRIP*R*VVRTKRGVLQVC*ENASV
RKARCVSF*Y*GIGYRPCRTP*LRVTGV**AVQ
RKNSHCPQKRNSLQNL*RCF*KWCR*SV*R*AF
**SDSVALFWQC**SKTCHVDALY*GQIRQR*RE
VDI*R*GGQDCEGG*RKTD*SVTVFS*QN*KAK
**TAVPREKGTP*KWQRIFFSKPYQ*QP*ESAT
DRTAGIQ**VG*GKTAWP*WTRLPQGRGEGTQSA
QQPREDGSLPTD*GQQVHSGSQRKYFTEQSTRW
APVWIPAQTI*TQFH*IKI*TRHTRKK*GHVSR
RQKVRWPVQNPS*KNTGEQATRLPSFC*RKTAEG
HRPPR*KCICAKRFYGIKNQR*ACPKQRNCCK*
FWL**CEKTEN*NVK*SNA*LFF*AAG*RLGMS
YNLRFSN*GTMGQKGL*NMGEFGSH*Q*VSERKT
FACTCS*CKRESHWSP*E*KC*SKE*IYVCD*E
RTQIVNKRLSLRN*RNDCKISLQKSLI*GICCE
RRGPSRRIA*SAFQEERELSSVTHSRQSC**EEN
AVF*YSRWFL*TVGISKT*TITKIVPVKHE*RD
S*DTAL*FYRR*KSYLFRNQQSFQTPELCRFMP
TSRGNRNLPHQIS*FFRV*PRKGISL**CIRPQS
H*WIGKTRTTSPDRGRERDKNFTRLCQFCTSGE
AI*KGDTTRRCKKNHKSGM*DSTRNQGDLLYN*
TAKATSFSPR*SRR*YSRASILSRQLWEKPFNPR
NTQFRGSEL*IYI*DT*LAHSLYTRQTQPNSRG
F*GVRGGGTGQVNLP*ADYSGGNSS*A*NA**R
EQRL*PKTQK*QSCLY*ISPSSTTGCGPD*VR*E
ASLSPRKRG*HD*SQSAR*A*QVPAG*TCH*SA
ATFTSSSRGRRQ*FKR*RIYLSASPS*KIYLQI
KGSGR*TKRKTQSFC*KGFQPERTGK*WIWKR**
IWPWP*FTSE*NCPEWEQRPVHHRVFHCHHSRV
FS*HGCHRDRLSGWL*PAR*R*WLDRE*F*TPN
SSHGN*ERYLEHRGHSEAS*PLF*PK*T*SYRGG
GKGGTR*GQATF*KFFI*KDS**D*SEVRGPVL
HTGRQTS*QISVS*YLLQLQSR*RICHSF*NSS
YQRSRF*PLV**PRG**SF*Q*ITGR*N*AIWAG
GRRPLSSNNP*YNASQNAN**KYPN**A*PLPI
S*RKNV*DDSQWCN*HEQEGFC*REAPIFPDW*
AYF*REVRGPGGRG*KYGHCHTTATVRGHHCRNQ
SREKCRDTYSGT*PQHPDQRRVSGRHIQ*WLPG
EISSSH*HL*S*PQVAHAYKNGNFCIHHDHEER
RPWRNNR*DRSGDDQLSGIRK*NYNNDFKYSQ*P
DGR*AP*KT*FSKR*L**QQQFGFFHYTDR*HY
E*YSSDRTFCTHLYHRER*PSESLIRKKDRGTT
RTLCKR*AESSWRTAKNKGIDRD*AKIQTSHKGH
FTKRYLPTEPYVKH*SK*NEAG*SIRENQSPYY
FFMCRCKVQNSSEKHTQG*HNCS*KSMCHTKAR
AARERQGQTASIQVASKGKIHLCHYHHHHCHHHH
HYHHYHHHQLHS*S*EKSAQGSM*TFH*IF*GN
*W*DLKACGPPL*RRKKDAVRVVR*GRKYLKKH
VVVRDFPGWPAFGYNEVC*R*ENRGSTFKIKE*K
GRQ*EKEQ*KDWSTESM*TDRYQDGNSSRSPGT
*LDRTGKGTEFFSG*NQSNTCGKSKFFNFSELH
VIKKMGYQRRKKCHN*CLNFGLDKN*SNRYSDTA
RRTNI*LWKYFRHQKFCR*EQCFP*PC*WLAE*
DIKWKPRVLRSSSKSNWWVTRSTG*QP*PV*RF
HYLISQRRSWQI*SKWKPYRNHSRSKDKILLSRI
PK*CRKTEYQGNSETKNTWIWSC*RTSITTSSI
SEISRRNQQAYNRRD*TLCACQYEKDE*DFSSR
WQAKA*PP*RRGVQWV*AKAGRRF*GENEERNPA
CGKEEPLVTANGQSRIISFYCQY*EIRGRNVSR
K*KFTEKCVCVRCFHTLMA*FFLCKKKRKENHP
HFNLA*ANLQSMEITFISGLARVQLAMQCIYKKP
CC*QFISSNLVSFTKGRNSCHQKGQKEME*SNH
RETLKLLNLQQLALFFLDPNCQGINTICFFFKT
SIVLL*IITLYKF*QKNRIKC**GTAS*NTNRIL
QMHLTNRGLK*LHPRRGGRDSGWG*LFTDSCIL
AIIMFVYAKLLA*F*KKTNL*NLLQI*IIPKMR
NSVVL*KIFFFRILIF*CMCITLF*LNLFQFCKH
YSILQHKRFYL*TQSPSSNICCYCQFFNEMT*K
QQKKITYTVVALGGGGMLSVSA*KGVNACRFRG
GWCS*KAPVGGI*KGLNRNP*LVEWQHAVKLLLY
CVLAIRCRHLSVSQSFVTILAVSY*VNKAAVF*
RAFLFGFW*NSLIC*LYSHKISIH*HIALMTYV
*KTIHWMT*SII*A*NKLC*TLHL

Sequence NM_001149

GGAGCTCCATGCCACTCCCCGCCTGGGCCACTGCTTTGTTTTCTTCTAATGTTTTTCCTCTACCTGGGTTGGCTGTTTCTTCATTCATATTTGAGAAGAA
TCACCTCCTAATTAAATGTAGCACTTCGCTCTCTCCCTACATGAAGGCTGTCTTGGTTACCCGACTAGGCAACGCGCATTGGTATCAAATTACCGAAAGT
CTACACCGGAGCAGTCCTCATATTTACATACAAATAACTCAGGGGCTTGCATTTATGTCACCATTCTGTCCTGCTAGAGGCTTGCCAGAGGAGTTTTTAA
TCCAATCAGAAGGAGCTTTAAAAGGATGTCTGCGAAGTGGTCAAAAGGATCTTAACCTCAATTAAGTGGGGTTTTTTAAAAAGATTTTTTTGGGGGCCTG
AAATTTTGAAAATCTTCGAACTCTGAGTGGGGAAAGATGTATAATTCCTCAATTGCCTACGAGGATATCAAGATGCTGAGAGGAATTCAGCGGTGGTGAA
GAGAGTGGATACAAACCAGGGATTGGTTTCCTTGAGCTGTTTTGGAGGTTGATTCTAAATCACTGCTTAAGGAATTCCTGGAAACATCAGGAAAACATTT
GATCATCCAAGCCTAGTGGAAATGGCTTTACCGCAGAGTGAAGATGCAATGACCGGGGACACAGACAAATATCTTGGGCCACAGGACCTTAAGGAATTGG
GTGATGATTCCCTGCCTGCAGAGGGTTACATGGGCTTTAGTCTCGGAGCGCGTTCTGCCAGCCTCCGCTCCTTCAGTTCGGATAGGTCTTACACCTTGAA
CAGAAGCTCCTATGCACGGGACAGCATGATGATTGAAGAACTCCTTGTGCCATCCAAAGAGCAGCATCTAACATTCACAAGGGAATTTGATTCAGATTCT
CTTAGACATTACAGCTGGGCTGCAGACACCTTAGACAATGTCAATCTTGTTTCAAGCCCCATTCATTCTGGGTTTCTGGTTAGCTTTATGGTGGACGCGA
GAGGGGGCTCCATGAGAGGAAGCCGTCATCACGGGATGAGAATCATCATTCCTCCACGCAAGTGTACGGCCCCCACTCGAATCACCTGCCGTTTGGTAAA
GAGACATAAACTGGCCAACCCACCCCCCATGGTGGAAGGAGAGGGATTAGCCAGTAGGCTGGTAGAAATGGGTCCTGCAGGGGCACAATTTTTAGGCCCT
GTCATAGTGGAAATCCCTCACTTTGGGTCCATGAGAGGAAAAGAGAGAGAACTCATTGTTCTTCGAAGTGAAAATGGTGAAACTTGGAAGGAGCATCAGT
TTGACAGCAAAAATGAAGATTTAACCGAGTTACTTAATGGCATGGATGAAGAACTTGATAGCCCAGAAGAGTTAGGGAAAAAGCGTATCTGCAGGATTAT
CACGAAAGATTTCCCCCAGTATTTTGCAGTGGTTTCCCGGATTAAGCAGGAAAGCAACCAGATTGGTCCTGAAGGTGGAATTCTGAGCAGCACCACAGTG
CCCCTTGTTCAAGCATCTTTCCCAGAGGGTGCCCTAACTAAAAGAATTCGAGTGGGCCTCCAGGCCCAGCCTGTTCCAGATGAAATTGTGAAAAAGATCC
TTGGAAACAAAGCAACTTTTAGCCCAATTGTCACTGTGGAACCAAGAAGACGGAAATTCCATAAACCAATCACAATGACCATTCCGGTGCCCCCGCCCTC
AGGAGAAGGTGTATCCAATGGATACAAAGGGGACACTACACCCAATCTGCGTCTTCTCTGTAGCATTACAGGGGGCACTTCGCCTGCTCAGTGGGAAGAC
ATCACAGGAACAACTCCTTTGACGTTTATAAAAGATTGTGTCTCCTTTACAACCAATGTTTCAGCCAGATTTTGGCTTGCAGACTGCCATCAAGTTTTAG
AAACTGTGGGGTTAGCCACGCAACTGTACAGAGAATTGATATGTGTTCCATATATGGCCAAGTTTGTTGTTTTTGCCAAAATGAATGATCCCGTAGAATC
TTCCTTGCGATGTTTCTGCATGACAGATGACAAAGTGGACAAAACTTTAGAGCAACAAGAGAATTTTGAGGAAGTCGCAAGAAGCAAAGATATTGAGGTT
CTGGAAGGAAAACCTATTTATGTTGATTGTTATGGAAATTTGGCCCCACTTACCAAAGGAGGACAGCAACTTGTTTTTAACTTTTATTCTTTCAAAGAAA
ATAGACTGCCATTTTCCATCAAGATTAGAGACACCAGCCAAGAGCCCTGTGGTCGTCTGTCTTTTCTGAAAGAACCAAAGACAACAAAAGGACTGCCTCA
AACAGCGGTTTGCAACTTAAATATCACTCTGCCAGCACATAAAAAGATTGAGAAAACAGATAGACGACAGAGCTTCGCATCCTTAGCTTTACGTAAGCGC
TACAGCTACTTGACTGAGCCTGGAATGAGTCCACAGAGTCCATGTGAACGGACAGATATCAGGATGGCAATAGTAGCCGATCACCTGGGACTTAGTTGGA
CAGAACTGGCAAGGGAACTGAATTTTTCAGTGGATGAAATCAATCAAATACGTGTGGAAAATCCAAATTCTTTAATTTCTCAGAGCTTCATGTTATTAAA
AAAATGGGTTACCAGAGACGGAAAAAATGCCACAACTGATGCCTTAACTTCGGTCTTGACAAAAATTAATCGAATAGATATAGTGACACTGCTAGAAGGA
CCAATATTTGATTATGGAAATATTTCAGGCACCAGAAGTTTTGCAGATGAGAACAATGTTTTCCATGACCCTGTTGATGGTTATCCTTCCCTTCAAGTGG
AACTGGAAACCCCCACAGGGTTGCACTACACACCACCTACCCCTTTCCAGCAAGATGATTATTTTAGTGATATCTCTAGCATAGAATCTCCCCTTAGAAC
CCCTAGTAGACTGAGTGATGGGCTAGTGCCTTCCCAGGGGAACATAGAGCATTCCGCAGATGGACCTCCAGTCGTAACTGCAGAAGACGCTTCCTTAGAA
GACAGCAAACTGGAAGACTCAGTGCCTTTAACAGAAATGCCTGAAGCAGTGGATGTAGATGAGAGCCAGTTGGAGAATGTATGTCTGA
GTTGGCAGAATG
AGACATCAAGTGGAAACCTAGAGTCCTGCGCTCAAGCTCGAAGAGTAACTGGTGGGTTACTAGATCGACTGGATGACAGCCCTGACCAGTGTAGAGATTC
CATTACCTCATATCTCAAAGGAGAAGCTGGCAAATTTGAAGCAAATGGAAGCCATACAGAAATCACTCCAGAAGCAAAGACAAAATCTTACTTTCCAGAA
TCCCAAAATGATGTAGGAAAACAGAGTACCAAGGAAACTCTGAAACCAAAAATACATGGATCTGGTCATGTTGAAGAACCAGCATCACCACTAGCAGCAT
ATCAGAAATCTCTAGAAGAAACCAGCAAGCTTATAATAGAAGAGACTAAACCCTGTGTGCCTGTCAGTATGAAAAAGATGAGTAGGACTTCTCCAGCAGA
TGGCAAGCCAAGGCTTAGCCTCCATGAAGAAGAGGGGTCCAGTGGGTCTGAGCAAAAGCAGGGAGAAGGTTTTAAGGTGAAAACGAAGAAAGAAATCCGG
CATGTGGAAAAGAAGAGCCACTCGTAACAGCGAACGGTCAGTCAAGGATCATAAGTTTTTACTGCCAGTATTGAGAAATTCGTGGAAGAAATGTCAGCAG
GAAGTAAAAATTCACCGAGAAGTGTGTGTGTGTTCGCTGCTTCCACACATTAATGGCATGATTTTTTTTATGCAAAAAGAAAAGAAAAGAAAACCACCCA
CATTTTAATTTAGCATGAGCCAATTTACAGAGCATGGAAATCACTTTCATTTCCGGATTGGCGCGTGTGCAATTAGCAATGCAGTGTATATACAAGAAGC
CATGCTGTTAACAGTTTATCTCAAGTAATTTGGTGTCATTTACAAAAGGAAGAAATTCCTGCCATCAGAAGGGACAGAAGGAGATGGAATGATCAAATCA
CAGAGAAACACTAAAATTACTAAATCTACAACAGCTCGCCTTATTTTTCTTGGACCCAAACTGTCAGGGTATAAACACTATTTGTTTCTTTTTTAAAACA
TCGATAGTTTTGCTGTAAATAATAACACTGTATAAATTCTAACAGAAAAATAGAATAAAATGTTGATAAGGCACTGCCTCTTAGAACACAAACAGAATAT
TGCAAATGCATTTAACAAATAGGGGTCTCAAGTGACTTCACCCTAGAAGAGGAGGGAGGGATTCTGGGTGGGGGTGACTCTTCACTGATTCTTGTATATT
AGCAATTATAATGTTTGTATATGCAAAACTGCTAGCTTGATTTTAAAAAAAAACAAATCTTTAAAATCTGCTGCAAATTTAAATAATTCCCAAAATGAGG
AATTCTGTAGTTCTGTGAAAAATTTTTTTCTTCAGAATACTAATATTTTGATGCATGTGTATCACCTTATTTTGATTAAATCTTTTCCAATTTTGCAAAC
ACTACAGTATACTGCAACACAAAAGATTTTATCTGTAAACACAAAGCCCTTCATCTAATATTTGTTGCTATTGCCAATTTTTCAATGAAATGACCTAAAA
ACAACAAAAAAAAATAACCTATACGGTAGTTGCTTTAGGGGGTGGGGGGATGCTATCTGTTAGTGCTTAAAAGGGGGTAAATGCTTGCCGCTTTAGAGGT
GGATGGTGCTCATAAAAGGCCCCAGTCGGGGGTATTTAAAAAGGACTGAACAGAAATCCTTAGCTAGTAGAATGGCAGCACGCTGTAAAATTATTACTGT
ATTGTGTACTGGCTATAAGATGTAGACACCTTTCAGTAAGCCAATCATTTGTAACCATTCTAGCAGTGTCATATTAGGTTAATAAGGCTGCTGTGTTTTA
AAGGGCATTTTTATTTGGGTTTTGGTGAAATTCTTTAATTTGTTGATTATATTCACATAAAATCAGCATTCATTGACACATAGCTCTAATGACATATGTA
TGAAAAACCATACACTGGATGACCTAGTCGATTATTTAAGCATAAAATAAATTGTGTTAAACTCTTCACCTA
  • refseq_ANK3.F1 (forward primer)
  • refseq_ANK3.R1 (reverse primer)
  • Single exon skipping

Frame 0

GAPCHSPPGPLLCFLLMFFLYLGWLFLHSYLRR
ITS*LNVALRSLPT*RLSWLPD*ATRIGIKLPKV
YTGAVLIFTYK*LRGLHLCHHSVLLEACQRSF*
SNQKEL*KDVCEVVKRILTSIKWGFLKRFFWGP
EILKIFEL*VGKDV*FLNCLRGYQDAERNSAVVK
RVDTNQGLVSLSCFGG*F*ITA*GIPGNIRKTF
DHPSLVEMALPQSEDAMTGDTDKYLGPQDLKEL
GDDSLPAEGYMGFSLGARSASLRSFSSDRSYTLN
RSSYARDSMMIEELLVPSKEQHLTFTREFDSDS
LRHYSWAADTLDNVNLVSSPIHSGFLVSFMVDA
RGGSMRGSRHHGMRIIIPPRKCTAPTRITCRLVK
RHKLANPPPMVEGEGLASRLVEMGPAGAQFLGP
VIVEIPHFGSMRGKERELIVLRSENGETWKEHQ
FDSKNEDLTELLNGMDEELDSPEELGKKRICRII
TKDFPQYFAVVSRIKQESNQIGPEGGILSSTTV
PLVQASFPEGALTKRIRVGLQAQPVPDEIVKKI
LGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPS
GEGVSNGYKGDTTPNLRLLCSITGGTSPAQWED
ITGTTPLTFIKDCVSFTTNVSARFWLADCHQVL
ETVGLATQLYRELICVPYMAKFVVFAKMNDPVES
SLRCFCMTDDKVDKTLEQQENFEEVARSKDIEV
LEGKPIYVDCYGNLAPLTKGGQQLVFNFYSFKE
NRLPFSIKIRDTSQEPCGRLSFLKEPKTTKGLPQ
TAVCNLNITLPAHKKIEKTDRRQSFASLALRKR
YSYLTEPGMSPQSPCERTDIRMAIVADHLGLSW
TELARELNFSVDEINQIRVENPNSLISQSFMLLK
KWVTRDGKNATTDALTSVLTKINRIDIVTLLEG
PIFDYGNISGTRSFADENNVFHDPVDGYPSLQV
ELETPTGLHYTPPTPFQQDDYFSDISSIESPLRT
PSRLSDGLVPSQGNIEHSADGPPVVTAEDASLE
DSKLEDSVPLTEMPEAVDVDESQLENVCL
SWQN
ETSSGNLESCAQARRVTGGLLDRLDDSPDQCRDS
ITSYLKGEAGKFEANGSHTEITPEAKTKSYFPE
SQNDVGKQSTKETLKPKIHGSGHVEEPASPLAA
YQKSLEETSKLIIEETKPCVPVSMKKMSRTSPAD
GKPRLSLHEEEGSSGSEQKQGEGFKVKTKKEIR
HVEKKSHS*QRTVSQGS*VFTASIEKFVEEMSA
GSKNSPRSVCVFAASTH*WHDFFYAKRKEKKTTH
ILI*HEPIYRAWKSLSFPDWRVCN*QCSVYTRS
HAVNSLSQVIWCHLQKEEIPAIRRDRRRWNDQI
TEKH*NY*IYNSSPYFSWTQTVRV*TLFVSFLKH
R*FCCK**HCINSNRKIE*NVDKALPLRTQTEY
CKCI*QIGVSSDFTLEEEGGILGGGDSSLILVY
*QL*CLYMQNC*LDFKKKQIFKICCKFK*FPK*G
IL*FCEKFFSSEY*YFDACVSPYFD*IFSNFAN
TTVYCNTKDFICKHKALHLIFVAIANFSMK*PK
NNKKK*PIR*LL*GVGGCYLLVLKRG*MLAALEV
DGAHKRPQSGVFKKD*TEILS**NGSTL*NYYC
IVYWL*DVDTFQ*ANHL*PF*QCHIRLIRLLCF
KGHFYLGFGEIL*FVDYIHIKSAFIDT*L**HMY
EKPYTG*PSRLFKHKINCVKLFT

Frame 1

ELHATPRLGHCFVFF*CFSSTWVGCFFIHI*EE
SPPN*M*HFALSLHEGCLGYPTRQRALVSNYRK
STPEQSSYLHTNNSGACIYVTILSC*RLARGVFN
PIRRSFKRMSAKWSKGS*PQLSGVF*KDFFGGL
KF*KSSNSEWGKMYNSSIAYEDIKMLRGIQRW*
REWIQTRDWFP*AVLEVDSKSLLKEFLETSGKHL
IIQA*WKWLYRRVKMQ*PGTQTNILGHRTLRNW
VMIPCLQRVTWALVSERVLPASAPSVRIGLTP*
TEAPMHGTA**LKNSLCHPKSSI*HSQGNLIQIL
LDITAGLQTP*TMSILFQAPFILGFWLALWWTR
EGAP*EEAVITG*ESSFLHASVRPPLESPAVW*
RDINWPTHPPWWKERD*PVGW*KWVLQGHNF*AL
S*WKSLTLGP*EEKRENSLFFEVKMVKLGRSIS
LTAKMKI*PSYLMAWMKNLIAQKS*GKSVSAGL
SRKISPSILQWFPGLSRKATRLVLKVEF*AAPQC
PLFKHLSQRVP*LKEFEWASRPSLFQMKL*KRS
LETKQLLAQLSLWNQEDGNSINQSQ*PFRCPRP
QEKVYPMDTKGTLHPICVFSVALQGALRLLSGKT
SQEQLL*RL*KIVSPLQPMFQPDFGLQTAIKF*
KLWG*PRNCTEN*YVFHIWPSLLFLPK*MIP*N
LPCDVSA*QMTKWTKL*SNKRILRKSQEAKILRF
WKENLFMLIVMEIWPHLPKEDSNLFLTFILSKK
IDCHFPSRLETPAKSPVVVCLF*KNQRQQKDCL
KQRFAT*ISLCQHIKRLRKQIDDRASHP*LYVSA
TAT*LSLE*VHRVHVNGQISGWQ**PITWDLVG
QNWQGN*IFQWMKSIKYVWKIQIL*FLRASCY*
KNGLPETEKMPQLMP*LRS*QKLIE*I**HC*KD
QYLIMEIFQAPEVLQMRTMFSMTLLMVILPFKW
NWKPPQGCTTHHLPLSSKMIILVISLA*NLPLE
PLVD*VMG*CLPRGT*SIPQMDLQS*LQKTLP*K
TANWKTQCL*QKCLKQWM*MRASWRMYV*
VGRM
RHQVET*SPALKLEE*LVGY*IDWMTALTSVEI
PLPHISKEKLANLKQMEAIQKSLQKQRQNLTFQN
PKMM*ENRVPRKL*NQKYMDLVMLKNQHHH*QH
IRNL*KKPASL**KRLNPVCLSV*KR*VGLLQQ
MASQGLASMKKRGPVGLSKSREKVLR*KRRKKSG
MWKRRATRNSERSVKDHKFLLPVLRNSWKKCQQ
EVKIHREVCVCSLLPHINGMIFFMQKEKKRKPP
TF*FSMSQFTEHGNHFHFRIGACAISNAVYIQEA
MLLTVYLK*FGVIYKRKKFLPSEGTEGDGMIKS
QRNTKITKSTTARLIFLGPKLSGYKHYLFLF*N
IDSFAVNNNTV*ILTEK*NKMLIRHCLLEHKQNI
ANAFNK*GSQVTSP*KRREGFWVGVTLH*FLYI
SNYNVCICKTASLILKKNKSLKSAANLNNSQNE
EFCSSVKNFFLQNTNILMHVYHLILIKSFPILQT
LQYTATQKILSVNTKPFI*YLLLLPIFQ*NDLK
TTKKNNLYGSCFRGWGDAIC*CLKGGKCLPL*R
WMVLIKGPSRGYLKRTEQKSLASRMAARCKIITV
LCTGYKM*TPFSKPIICNHSSSVILG**GCCVL
KGIFIWVLVKFFNLLIIFT*NQHSLTHSSNDIC
MKNHTLDDLVDYLSIK*IVLNSSP

Frame 2

SSMPLPAWATALFSSNVFPLPGLAVSSFIFEKN
HLLIKCSTSLSPYMKAVLVTRLGNAHWYQITES
LHRSSPHIYIQITQGLAFMSPFCPARGLPEEFL
IQSEGALKGCLRSGQKDLNLN*VGFFKKIFLGA*
NFENLRTLSGERCIIPQLPTRISRC*EEFSGGE
ESGYKPGIGFLELFWRLILNHCLRNSWKHQENI
*SSKPSGNGFTAE*RCNDRGHRQISWATGP*GIG
**FPACRGLHGL*SRSAFCQPPLLQFG*VLHLE
QKLLCTGQHDD*RTPCAIQRAASNIHKGI*FRF
S*TLQLGCRHLRQCQSCFKPHSFWVSG*LYGGRE
RGLHERKPSSRDENHHSSTQVYGPHSNHLPFGK
ET*TGQPTPHGGRRGISQ*AGRNGSCRGTIFRP
CHSGNPSLWVHERKRERTHCSSK*KW*NLEGASV
*QQK*RFNRVT*WHG*RT**PRRVREKAYLQDY
HERFPPVFCSGFPD*AGKQPDWS*RWNSEQHHS
APCSSIFPRGCPN*KNSSGPPGPACSR*NCEKDP
WKQSNF*PNCHCGTKKTEIP*TNHNDHSGAPAL
RRRCIQWIQRGHYTQSASSL*HYRGHFACSVGR
HHRNNSFDVYKRLCLLYNQCFSQILACRLPSSFR
NCGVSHATVQRIDMCSIYGQVCCFCQNE*SRRI
FLAMFLHDR*QSGQNFRATREF*GSRKKQRY*G
SGRKTYLC*LLWKFGPTYQRRTATCF*LLFFQRK
*TAIFHQD*RHQPRALWSSVFSERTKDNKRTAS
NSGLQLKYHSAST*KD*ENR*TTELRILSFT*A
LQLLD*AWNESTESM*TDRYQDGNSSRSPGT*LD
RTGKGTEFFSG*NQSNTCGKSKFFNFSELHVIK
KMGYQRRKKCHN*CLNFGLDKN*SNRYSDTARR
TNI*LWKYFRHQKFCR*EQCFP*PC*WLSFPSSG
TGNPHRVALHTTYPFPAR*LF**YL*HRISP*N
P**TE*WASAFPGEHRAFRRWTSSRNCRRRFLR
RQQTGRLSAFNRNA*SSGCR*EPVGECMSE
LAE*
DIKWKPRVLRSSSKSNWWVTRSTG*QP*PV*RF
HYLISQRRSWQI*SKWKPYRNHSRSKDKILLSR
IPK*CRKTEYQGNSETKNTWIWSC*RTSITTSSI
SEISRRNQQAYNRRD*TLCACQYEKDE*DFSSR
WQAKA*PP*RRGVQWV*AKAGRRF*GENEERNP
ACGKEEPLVTANGQSRIISFYCQY*EIRGRNVSR
K*KFTEKCVCVRCFHTLMA*FFLCKKKRKENHP
HFNLA*ANLQSMEITFISGLARVQLAMQCIYKK
PCC*QFISSNLVSFTKGRNSCHQKGQKEME*SNH
RETLKLLNLQQLALFFLDPNCQGINTICFFFKT
SIVLL*IITLYKF*QKNRIKC**GTAS*NTNRI
LQMHLTNRGLK*LHPRRGGRDSGWG*LFTDSCIL
AIIMFVYAKLLA*F*KKTNL*NLLQI*IIPKMR
NSVVL*KIFFFRILIF*CMCITLF*LNLFQFCK
HYSILQHKRFYL*TQSPSSNICCYCQFFNEMT*K
QQKKITYTVVALGGGGMLSVSA*KGVNACRFRG
GWCS*KAPVGGI*KGLNRNP*LVEWQHAVKLLL
YCVLAIRCRHLSVSQSFVTILAVSY*VNKAAVF*
RAFLFGFW*NSLIC*LYSHKISIH*HIALMTYV
*KTIHWMT*SII*A*NKLC*TLHL

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