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Sequences

Sequence NM_170771

GGGACAACCTGAGTGCTCAGTCGTAAAGAGGAAAGGCAGAATTTTTCCTTGCTATGGCTGGAACAAACGCACTTTTGATGCTGGAAAACTTCATAGATGG
AAAATTTTTACCTTGTAGCTCATATATAGATTCTTACGACCCATCAACAGGGGAAGTGTATTGCAGAGTGCCAAATAGTGGAAAAGACGAGATCGAAGCC
GCGGTCAAGGCCGCCAGAGAAGCCTTTCCCAGCTGGTCATCCCGCAGCCCCCAGGAGCGCTCACGGGTCCTGAACCAGGTGGCGGATTTGCTGGAGCAGT
CCCTGGAGGAGTTTGCCCAGGCCGAGTCTAAAGACCAAGGGAAAACCTTAGCACTGGCAAGAACCATGGACATTCCCCGGTCTGTGCAGAACTTCAGGTT
CTTCGCTTCCTCCAGCCTGCACCACACGTCAGAGTGCACGCAGATGGACCACCTGGGCTGCATGCACTACACGGTGCGGGCCCCGGTGGGAGTCGCTGGT
CTGATCAGCCCCTGGAATTTGCCACTCTACTTGCTGACCTGGAAGATAGCTCCAGCGATGGCTGCAGGGAACACTGTGATAGCCAAGCCCAGTGAGCTGA
CTTCAGTGACTGCGTGGATGTTGTGCAAACTCCTGGATAAAGCAGGTGTTCCACCAGGTGTGGTCAATATTGTGTTTGGAACCGGGCCCAGGGTGGGTGA
GGCCCTGGTGTCCCACCCAGAGGTGCCCCTGATCTCCTTCACCGGGAGCCAGCCCACCGCTGAGCGGATCACCCAGCTGAGCGCTCCCCACTGCAAAAAG
CTCTCCCTGGAGCTGGGGGGCAAGAATCCTGCCATCATCTTTGAGGACGCCAACCTGGATGAGTGCATTCCGGCAACCGTCAGGTCCAGCTTTGCCAACC
AGGTCAGAAGTTACGTCAAGAGAGCTCTTGCTGAAGGTGCCCAAATTTGGTGCGGTGAGGGAGTGGATAAGTTGAGCCTCCCTGCCAGGAACCAGGCAGG
CTACTTTATGCTTCCCACGGTGATAACAGACATTAAGGATGAATCCTGCTGCATGACGGAAGAGATATTTGGTCCAGTGACGTGTGTCGTCCCCTTTGAT
AGTGAAGAGGAGGTGATTGAAAGAGCCAACAACGTTAAGTATGGGCTGGCGGCTACCGTGTGGTCCAGCAATGTGGGGCGCGTCCACCGGGTGGCTAAGA
AGCTGCAGTCTGGCTTGGTCTGGACCAACTGCTGGCTCATCAGGGAGCTGAACCTTCCTTTCGGGGGGATGAAGAGTTCTGGAATAGGTAGAGAGGGAGC
CAAGGACTCTTACGACTTCTTCACTGAGATCAAAACCATCACCGTTAAACACTGATCTTTGCTAATGGTGGAGCCACTATGGCCAATGCCTGGCTGCAGG
CATCAGTTGTTCAATGTGGTAGATGAAAATCATGGCATGAATTCCAGCTATGCCTTGACTTGGCAGAAGGTTATCTCTAGCTTATCCTCAGTTCTTAGTA
ACTTTACCCACTAGTGAAGAGATACTGTCTATTTTCAATGTGGACTCGGAAAAAAAGACTTATAAGTAGGAAGATAGAACAATGATGCCAGTTGTCAGGC
TCCTCCCAGGTTATGTTTTCATAGTGTTTCTTTCATCATCTTCATTGAACTCTTGGGAATCTCCAGATAATCAGATTATTTCATTTGGTAAATTTTAAAA
AATATGCAATCAGGCACAGTGCCTCATGCCTATAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGATCACTTGAGTTCAGGAGTTCGAGATCAGCCTAG
GCAACATGGTGAAATCCTGTCTTTACCAAAAGTTTAAAAATTAGCTTGGTGTGGTGCCCTCTGCCTATAGCCCCAGCTACTTGGGAGGCTGAGGTGGGAG
GATCGCTTGAGCCCAGGCGGTTGAGGCTGCAGTGAGCCATGATCATTCCACTGCATTTCAGCCTGGGGGATACAGTGAGACCTTGTCTTTAAAAAAAAAA
TGCTGCAAAACCAAAAATAAATAGCCATAATTTGCCATCTTTGGAGAGATTATGGAGATAATCTCCTTGTCTATTAGCCACTAGCATGGCTAATTGATCA
TTGATTGGACCTCATTACATAAGGGGGCTGTGGACGTCTTTGGAATTTGTTAGGGGAAGGCTATGTGGTAAGCTCTACTAAATGTATCTGTACAAGGATG
AAGAAAAACAAAATAACTACTACTTTTGGAGGAAACTTGGAACAAGAAGAGTACATAGTTTGATCCATTCCTACGGTCGAGTCTAATCAATTCCATTTCT
TAGTGTATGCATCTAATGAGGCTTACAACTTGCTAACCCCAAAAGAAGCAATAAATGTTAAGCAATTTTAGTAACCAGTA
  • refseq_ALDH8A1.F1 (forward primer)
  • refseq_ALDH8A1.R1 (reverse primer)
  • Single exon skipping

Frame 0

GTT*VLSRKEERQNFSLLWLEQTHF*CWKTS*M
ENFYLVAHI*ILTTHQQGKCIAECQIVEKTRSKP
RSRPPEKPFPAGHPAAPRSAHGS*TRWRICWSS
PWRSLPRPSLKTKGKP*HWQEPWTFPGLCRTSG
SSLPPACTTRQSARRWTTWAACTTRCGPRWESLV
*SAPGICHSTC*PGR*LQRWLQGTL**PSPVS*
LQ*LRGCCANSWIKQVFHQVWSILCLEPGPGWV
RPWCPTQRCP*SPSPGASPPLSGSPS*ALPTAKS
SPWSWGARILPSSLRTPTWMSAFRQPSGPALPT
RSEVTSRELLLKVPKFGAVREWIS*ASLPGTRQ
ATLCFPR**QTLRMNPAA*RKRYLVQ*RVSSPLI
VKRR*LKEPTTLSMGWRLPCGPAMWGASTGWLR
SCSLAWSGPTAGSSGS*TFLSGG*RVLE*VERE
PRTLTTSSLRSKPSPLNTDLC*WWSHYGQCLAAG
ISCSMW*MKIMA*IPAMP*LGRRLSLAYPQFLV
TLPTSEEILSIFNVDSEKKTYK*EDRTMMPVVR
LLPGYVFIVFLSSSSLNSWESPDNQIISFGKF*K
ICNQAQCLMPIIPALWEAKVGGSLEFRSSRSA*
ATW*NPVFTKSLKISLVWCPLPIAPATWEAEVG
GSLEPRRLRLQ*AMIIPLHFSLGDTVRPCL*KKN
AAKPKINSHNLPSLERLWR*SPCLLATSMAN*S
LIGPHYIRGLWTSLEFVRGRLCGKLY*MYLYKD
EEKQNNYYFWRKLGTRRVHSLIHSYGRV*SIPFL
SVCI**GLQLANPKRSNKC*AILVTS

Frame 1

GQPECSVVKRKGRIFPCYGWNKRTFDAGKLHRW
KIFTL*LIYRFLRPINRGSVLQSAK*WKRRDRS
RGQGRQRSLSQLVIPQPPGALTGPEPGGGFAGAV
PGGVCPGRV*RPRENLSTGKNHGHSPVCAELQV
LRFLQPAPHVRVHADGPPGLHALHGAGPGGSRW
SDQPLEFATLLADLEDSSSDGCREHCDSQAQ*AD
FSDCVDVVQTPG*SRCSTRCGQYCVWNRAQGG*
GPGVPPRGAPDLLHREPAHR*ADHPAERSPLQK
ALPGAGGQESCHHL*GRQPG*VHSGNRQVQLCQP
GQKLRQESSC*RCPNLVR*GSG*VEPPCQEPGR
LLYASHGDNRH*G*ILLHDGRDIWSSDVCRPL*
**RGGD*KSQQR*VWAGGYRVVQQCGARPPGG*E
AAVWLGLDQLLAHQGAEPSFRGDEEFWNR*RGS
QGLLRLLH*DQNHHR*TLIFANGGATMANAWLQ
ASVVQCGR*KSWHEFQLCLDLAEGYL*LILSS**
LYPLVKRYCLFSMWTRKKRLISRKIEQ*CQLSG
SSQVMFS*CFFHHLH*TLGNLQIIRLFHLVNFK
KYAIRHSASCL*SQHFGRPRWVDHLSSGVRDQPR
QHGEILSLPKV*KLAWCGALCL*PQLLGRLRWE
DRLSPGG*GCSEP*SFHCISAWGIQ*DLVFKKK
MLQNQK*IAIICHLWRDYGDNLLVY*PLAWLIDH
*LDLIT*GGCGRLWNLLGEGYVVSSTKCICTRM
KKNKITTTFGGNLEQEEYIV*SIPTVESNQFHF
LVYASNEAYNLLTPKEAINVKQF**PV

Frame 2

DNLSAQS*RGKAEFFLAMAGTNALLMLENFIDG
KFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEA
AVKAAREAFPSWSSRSPQERSRVLNQVADLLEQ
SLEEFAQAESKDQGKTLALARTMDIPRSVQNFRF
FASSSLHHTSECTQMDHLGCMHYTVRAPVGVAG
LISPWNLPLYLLTWKIAPAMAAGNTVIAKPSEL
TSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGE
ALVSHPEVPLISFTGSQPTAERITQLSAPHCKK
LSLELGGKNPAIIFEDANLDECIPATVRSSFAN
QVRSYVKRALAEGAQIWCGEGVDKLSLPARNQAG
YFMLPTVITDIKDESCCMTEEIFGPVTCVVPFD
SEEEVIERANNVKYGLAATVWSSNVGRVHRVAK
KLQSGLVWTNCWLIRELNLPFGGMKSSGIGREGA
KDSYDFFTEIKTITVKH*SLLMVEPLWPMPGCR
HQLFNVVDENHGMNSSYALTWQKVISSLSSVLS
NFTH**RDTVYFQCGLGKKDL*VGR*NNDASCQA
PPRLCFHSVSFIIFIELLGISR*SDYFIW*ILK
NMQSGTVPHAYNPSTLGGQGGWIT*VQEFEISL
GNMVKSCLYQKFKN*LGVVPSAYSPSYLGG*GGR
IA*AQAVEAAVSHDHSTAFQPGGYSETLSLKKK
CCKTKNK*P*FAIFGEIMEIISLSISH*HG*LI
IDWTSLHKGAVDVFGIC*GKAMW*ALLNVSVQG*
RKTK*LLLLEETWNKKST*FDPFLRSSLINSIS
*CMHLMRLTTC*PQKKQ*MLSNFSNQ

Sequence NM_022568

GGGACAACCTGAGTGCTCAGTCGTAAAGAGGAAAGGCAGAATTTTTCCTTGCTATGGCTGGAACAAACGCACTTTTGATGCTGGAAAACTTCATAGATGG
AAAATTTTTACCTTGTAGCTCATATATAGATTCTTACGACCCATCAACAGGGGAAGTGTATTGCAGAGTGCCAAATAGTGGAAAAGACGAGATCGAAGCC
GCGGTCAAGGCCGCCAGAGAAGCCTTTCCCAGCTGGTCATCCCGCAGCCCCCAGGAGCGCTCACGGGTCCTGAACCAGGTGGCGGATTTGCTGGAGCAGT
CCCTGGAGGAGTTTGCCCAGGCCGAGTCTAAAGACCAAGGGAAAACCTTAGCACTGGCAAGAACCATGGACATTCCCCGGTCTGTGCAGAACTTCAGGTT
CTTCGCTTCCTCCAGCCTGCACCACACGTCAGAGTGCACGCAGATGGACCACCTGGGCTGCATGCACTACACGGTGCGGGCCCCGGTGGGAGTCGCTGGT
CTGATCAGCCCCTGGAATTTGCCACTCTACTTGCTGACCTGGAAGATAGCTCCAGCGATGGCTGCAGGGAACACTGTGATAGCCAAGCCCAGTGAGCTGA
CTTCAGTGACTGCGTGGATGTTGTGCAAACTCCTGGATAAAGCAGGTGTTCCACCAGGTGTGGTCAATATTGTGTTTGGAACCGGGCCCAGGGTGGGTGA
GGCCCTGGTGTCCCACCCAGAGGTGCCCCTGATCTCCTTCACCGGGAGCCAGCCCACCGCTGAGCGGATCACCCAGCTGAGCGCTCCCCACTGCAAAAAG
CTCTCCCTGGAGCTGGGGGGCAAGAATCCTGCCATCATCTTTGAGGACGCCAACCTGGATGAGTGCATTCCGGCAACCGTCAGGTCCAGCTTTGCCAACC
AGGGTGAAATCTGTCTCTGTACCAGCAGGATCTTTGTCCAGAAGAGCATCTATAGTGAATTTTTAAAGAGATTTGTAGAAGCTACCAGAAAGTGGAAAGT
CGGCATTCCCTCTGATCCACTGGTGAGCATAGGTGCTCTGATAAGTAAAGCACATTTGGAGAAAGTCAGAAGTTACGTCAAGAGAGCTCTTGCTGAAGGT
GCCCAAATTTGGTGCGGTGAGGGAGTGGATAAGTTGAGCCTCCCTGCCAGGAACCAGGCAGGCTACTTTATGCTTCCCACGGTGATAACAGACATTAAGG
ATGAATCCTGCTGCATGACGGAAGAGATATTTGGTCCAGTGACGTGTGTCGTCCCCTTTGATAGTGAAGAGGAGGTGATTGAAAGAGCCAACAACGTTAA
GTATGGGCTGGCGGCTACCGTGTGGTCCAGCAATGTGGGGCGCGTCCACCGGGTGGCTAAGAAGCTGCAGTCTGGCTTGGTCTGGACCAACTGCTGGCTC
ATCAGGGAGCTGAACCTTCCTTTCGGGGGGATGAAGAGTTCTGGAATAGGTAGAGAGGGAGCCAAGGACTCTTACGACTTCTTCACTGAGATCAAAACCA
TCACCGTTAAACACTGATCTTTGCTAATGGTGGAGCCACTATGGCCAATGCCTGGCTGCAGGCATCAGTTGTTCAATGTGGTAGATGAAAATCATGGCAT
GAATTCCAGCTATGCCTTGACTTGGCAGAAGGTTATCTCTAGCTTATCCTCAGTTCTTAGTAACTTTACCCACTAGTGAAGAGATACTGTCTATTTTCAA
TGTGGACTCGGAAAAAAAGACTTATAAGTAGGAAGATAGAACAATGATGCCAGTTGTCAGGCTCCTCCCAGGTTATGTTTTCATAGTGTTTCTTTCATCA
TCTTCATTGAACTCTTGGGAATCTCCAGATAATCAGATTATTTCATTTGGTAAATTTTAAAAAATATGCAATCAGGCACAGTGCCTCATGCCTATAATCC
CAGCACTTTGGGAGGCCAAGGTGGGTGGATCACTTGAGTTCAGGAGTTCGAGATCAGCCTAGGCAACATGGTGAAATCCTGTCTTTACCAAAAGTTTAAA
AATTAGCTTGGTGTGGTGCCCTCTGCCTATAGCCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATCGCTTGAGCCCAGGCGGTTGAGGCTGCAGTGAGCC
ATGATCATTCCACTGCATTTCAGCCTGGGGGATACAGTGAGACCTTGTCTTTAAAAAAAAAATGCTGCAAAACCAAAAATAAATAGCCATAATTTGCCAT
CTTTGGAGAGATTATGGAGATAATCTCCTTGTCTATTAGCCACTAGCATGGCTAATTGATCATTGATTGGACCTCATTACATAAGGGGGCTGTGGACGTC
TTTGGAATTTGTTAGGGGAAGGCTATGTGGTAAGCTCTACTAAATGTATCTGTACAAGGATGAAGAAAAACAAAATAACTACTACTTTTGGAGGAAACTT
GGAACAAGAAGAGTACATAGTTTGATCCATTCCTACGGTCGAGTCTAATCAATTCCATTTCTTAGTGTATGCATCTAATGAGGCTTACAACTTGCTAACC
CCAAAAGAAGCAATAAATGTTAAGCAATTTTAGTAACCAGTA
  • refseq_ALDH8A1.F1 (forward primer)
  • refseq_ALDH8A1.R1 (reverse primer)
  • Single exon skipping

Frame 0

GTT*VLSRKEERQNFSLLWLEQTHF*CWKTS*M
ENFYLVAHI*ILTTHQQGKCIAECQIVEKTRSKP
RSRPPEKPFPAGHPAAPRSAHGS*TRWRICWSS
PWRSLPRPSLKTKGKP*HWQEPWTFPGLCRTSG
SSLPPACTTRQSARRWTTWAACTTRCGPRWESLV
*SAPGICHSTC*PGR*LQRWLQGTL**PSPVS*
LQ*LRGCCANSWIKQVFHQVWSILCLEPGPGWV
RPWCPTQRCP*SPSPGASPPLSGSPS*ALPTAKS
SPWSWGARILPSSLRTPTWMSAFRQPSGPALPT
RVKSVSVPAGSLSRRASIVNF*RDL*KLPESGK
SAFPLIHW*A*VL**VKHIWRKSEVTSRELLLKV
PKFGAVREWIS*ASLPGTRQATLCFPR**QTLR
MNPAA*RKRYLVQ*RVSSPLIVKRR*LKEPTTL
SMGWRLPCGPAMWGASTGWLRSCSLAWSGPTAGS
SGS*TFLSGG*RVLE*VEREPRTLTTSSLRSKP
SPLNTDLC*WWSHYGQCLAAGISCSMW*MKIMA
*IPAMP*LGRRLSLAYPQFLVTLPTSEEILSIFN
VDSEKKTYK*EDRTMMPVVRLLPGYVFIVFLSS
SSLNSWESPDNQIISFGKF*KICNQAQCLMPII
PALWEAKVGGSLEFRSSRSA*ATW*NPVFTKSLK
ISLVWCPLPIAPATWEAEVGGSLEPRRLRLQ*A
MIIPLHFSLGDTVRPCL*KKNAAKPKINSHNLP
SLERLWR*SPCLLATSMAN*SLIGPHYIRGLWTS
LEFVRGRLCGKLY*MYLYKDEEKQNNYYFWRKL
GTRRVHSLIHSYGRV*SIPFLSVCI**GLQLAN
PKRSNKC*AILVTS

Frame 1

GQPECSVVKRKGRIFPCYGWNKRTFDAGKLHRW
KIFTL*LIYRFLRPINRGSVLQSAK*WKRRDRS
RGQGRQRSLSQLVIPQPPGALTGPEPGGGFAGAV
PGGVCPGRV*RPRENLSTGKNHGHSPVCAELQV
LRFLQPAPHVRVHADGPPGLHALHGAGPGGSRW
SDQPLEFATLLADLEDSSSDGCREHCDSQAQ*AD
FSDCVDVVQTPG*SRCSTRCGQYCVWNRAQGG*
GPGVPPRGAPDLLHREPAHR*ADHPAERSPLQK
ALPGAGGQESCHHL*GRQPG*VHSGNRQVQLCQP
G*NLSLYQQDLCPEEHL**IFKEICRSYQKVES
RHSL*STGEHRCSDK*STFGESQKLRQESSC*R
CPNLVR*GSG*VEPPCQEPGRLLYASHGDNRH*G
*ILLHDGRDIWSSDVCRPL***RGGD*KSQQR*
VWAGGYRVVQQCGARPPGG*EAAVWLGLDQLLA
HQGAEPSFRGDEEFWNR*RGSQGLLRLLH*DQNH
HR*TLIFANGGATMANAWLQASVVQCGR*KSWH
EFQLCLDLAEGYL*LILSS**LYPLVKRYCLFS
MWTRKKRLISRKIEQ*CQLSGSSQVMFS*CFFHH
LH*TLGNLQIIRLFHLVNFKKYAIRHSASCL*S
QHFGRPRWVDHLSSGVRDQPRQHGEILSLPKV*
KLAWCGALCL*PQLLGRLRWEDRLSPGG*GCSEP
*SFHCISAWGIQ*DLVFKKKMLQNQK*IAIICH
LWRDYGDNLLVY*PLAWLIDH*LDLIT*GGCGR
LWNLLGEGYVVSSTKCICTRMKKNKITTTFGGNL
EQEEYIV*SIPTVESNQFHFLVYASNEAYNLLT
PKEAINVKQF**PV

Frame 2

DNLSAQS*RGKAEFFLAMAGTNALLMLENFIDG
KFLPCSSYIDSYDPSTGEVYCRVPNSGKDEIEA
AVKAAREAFPSWSSRSPQERSRVLNQVADLLEQ
SLEEFAQAESKDQGKTLALARTMDIPRSVQNFRF
FASSSLHHTSECTQMDHLGCMHYTVRAPVGVAG
LISPWNLPLYLLTWKIAPAMAAGNTVIAKPSEL
TSVTAWMLCKLLDKAGVPPGVVNIVFGTGPRVGE
ALVSHPEVPLISFTGSQPTAERITQLSAPHCKK
LSLELGGKNPAIIFEDANLDECIPATVRSSFAN
QGEICLCTSRIFVQKSIYSEFLKRFVEATRKWKV
GIPSDPLVSIGALISKAHLEKVRSYVKRALAEG
AQIWCGEGVDKLSLPARNQAGYFMLPTVITDIK
DESCCMTEEIFGPVTCVVPFDSEEEVIERANNVK
YGLAATVWSSNVGRVHRVAKKLQSGLVWTNCWL
IRELNLPFGGMKSSGIGREGAKDSYDFFTEIKT
ITVKH*SLLMVEPLWPMPGCRHQLFNVVDENHGM
NSSYALTWQKVISSLSSVLSNFTH**RDTVYFQ
CGLGKKDL*VGR*NNDASCQAPPRLCFHSVSFI
IFIELLGISR*SDYFIW*ILKNMQSGTVPHAYNP
STLGGQGGWIT*VQEFEISLGNMVKSCLYQKFK
N*LGVVPSAYSPSYLGG*GGRIA*AQAVEAAVS
HDHSTAFQPGGYSETLSLKKKCCKTKNK*P*FAI
FGEIMEIISLSISH*HG*LIIDWTSLHKGAVDV
FGIC*GKAMW*ALLNVSVQG*RKTK*LLLLEET
WNKKST*FDPFLRSSLINSIS*CMHLMRLTTC*P
QKKQ*MLSNFSNQ

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