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Sequences

Sequence NM_001001344

GTGTCCACGCTTAGCAGCTTTCTCACCGCCGCCAAACCTTGCCTGGGCACTGGGACCGTGGGTGGCCGCCTGTCCCTAGCTGTGGCTGAGCCAAGATTGC
ACTTGTGAGAAGGCCTGACAGGCAGCATGGGCGACATGGCCAATAGTTCCATCGAGTTCCACCCCAAGCCCCAGCAGCAGCGGGATGTCCCCCAGGCTGG
AGGCTTTGGGTGCACGCTGGCGGAGCTGCGCACCCTCATGGAGCTGCGAGGGGCCGAGGCGCTGCAGAAGATCGAGGAGGCCTACGGGGATGTCAGCGGG
CTCTGCCGGAGGCTGAAGACCTCACCCACAGAGGGCCTGGCGGACAACACCAATGACCTGGAGAAGCGCAGGCAGATCTACGGGCAGAACTTCATCCCCC
CAAAGCAACCCAAGACCTTCCTGCAGCTGGTGTGGGAGGCCCTGCAGGACGTGACCCTCATCATCCTGGAGGTGGCTGCCATCGTCTCTCTGGGCCTCTC
GTTCTATGCGCCGCCAGGAGAGGAGAGTGAAGCCTGTGGGAATGTGTCGGGAGGCGCAGAAGATGAGGGCGAGGCCGAAGCTGGCTGGATCGAGGGGGCT
GCCATCCTGCTGTCCGTCATCTGTGTGGTGCTGGTCACGGCCTTCAATGACTGGAGCAAGGAGAAGCAGTTCCGAGGCCTGCAGAGCCGAATTGAGCAGG
AGCAGAAGTTCACGGTCATCCGGAACGGGCAGCTCCTCCAGGTCCCCGTGGCTGCGCTGGTGGTGGGGGACATTGCCCAGGTCAAGTACGGCGACCTGCT
GCCAGCCGACGGCGTGCTCATCCAGGCCAATGACCTCAAGATCGACGAGAGCTCCCTGACGGGCGAGTCTGACCACGTGCGCAAGTCAGCTGACAAAGAT
CCCATGCTGCTCTCAGGCACTCATGTCATGGAAGGTTCTGGAAGAATGGTGGTGACCGCCGTTGGCGTGAATTCCCAGACAGGCATCATCTTCACGCTGC
TTGGAGCTGGCGGAGAGGAGGAAGAGAAGAAAGATAAGAAAGGCAAGCAGCAGGATGGGGCCATGGAGAGTAGCCAGACCAAAGCTAAGAAGCAGGATGG
TGCAGTGGCCATGGAGATGCAGCCCCTGAAGAGCGCGGAGGGTGGGGAGATGGAGGAGCGGGAGAAGAAGAAAGCCAACGCACCCAAAAAGGAGAAGTCT
GTCCTTCAGGGGAAGCTCACAAAGCTAGCCGTGCAGATCGGGAAAGCAGGGCTGGTGATGTCTGCCATCACCGTCATCATCCTGGTCCTCTACTTTGTGA
TTGAGACGTTTGTCGTGGAAGGCCGGACATGGCTGGCAGAGTGCACGCCGGTCTATGTACAATACTTCGTGAAGTTCTTCATCATTGGTGTCACTGTGCT
GGTCGTGGCTGTCCCAGAGGGCCTGCCTCTTGCTGTCACCATCTCCTTAGCTTACTCTGTCAAGAAAATGATGAAAGACAACAACCTGGTGCGCCACCTG
GATGCCTGCGAGACCATGGGCAACGCCACAGCCATCTGCTCCGACAAGACGGGCACGCTCACCACCAACCGTATGACCGTGGTCCAGTCCTACCTAGGAG
ACACCCACTACAAAGAGATTCCGGCCCCCAGCGCCCTGACCCCTAAGATCCTCGACCTCCTGGTCCATGCCATCTCCATCAACAGTGCCTATACCACCAA
AATACTACCTCCTGAGAAGGAAGGCGCCCTCCCACGCCAGGTGGGCAATAAGACGGAGTGCGCCCTGCTGGGCTTCGTCTTGGACCTGAAGCGGGACTTC
CAGCCCGTGCGCGAGCAGATCCCGGAAGACAAGCTTTACAAAGTGTACACCTTCAACTCGGTCCGCAAGTCCATGAGCACAGTCATCCGCATGCCCGACG
GTGGCTTCCGCCTCTTCAGCAAGGGGGCCTCAGAGATCCTCTTGAAAAAGTGCACCAACATCTTGAACAGCAATGGCGAACTCCGGGGCTTTCGGCCTCG
GGACCGGGACGACATGGTGAGGAAGATCATCGAGCCGATGGCTTGCGATGGCCTCCGCACCATCTGCATCGCCTACCGGGACTTCTCTGCAGGCCAGGAG
CCCGACTGGGACAACGAGAATGAGGTCGTGGGTGACCTCACCTGCATAGCTGTCGTGGGCATTGAGGACCCTGTGCGGCCCGAGGTCCCTGAAGCTATCC
GAAAATGCCAGCGTGCTGGCATCACAGTCCGCATGGTGACTGGGGACAACATCAACACGGCCCGGGCCATCGCAGCCAAATGCGGCATCATCCAGCCCGG
GGAGGACTTCCTGTGCCTAGAAGGGAAGGAGTTCAACCGGCGGATCCGCAATGAGAAAGGCGAGATAGAACAGGAGCGGCTGGACAAGGTGTGGCCCAAG
CTGAGGGTGCTGGCCCGGTCGTCTCCCACCGACAAGCACACACTGGTCAAAGGGATTATCGACAGCACCACTGGTGAGCAGCGGCAGGTGGTGGCTGTGA
CAGGGGATGGCACCAACGATGGGCCGGCCCTCAAGAAGGCGGACGTGGGCTTCGCCATGGGCATCGCAGGGACCGACGTGGCCAAGGAGGCCTCCGACAT
CATCCTGACCGATGACAACTTCACCAGCATCGTCAAGGCAGTCATGTGGGGCCGTAACGTCTATGACAGCATCTCCAAGTTCCTGCAGTTTCAACTGACG
GTCAATGTGGTGGCTGTGATCGTGGCCTTCACAGGTGCCTGCATTACTCAGGACTCTCCTCTCAAAGCCGTGCAGATGTTGTGGGTGAACTTGATCATGG
ACACATTTGCCTCTCTGGCCCTGGCGACGGAGCCACCCACAGAGTCGCTGCTGCTGCGGAAGCCGTACGGCCGCGACAAGCCCCTCATCTCCCGCACCAT
GATGAAGAACATTCTGGGCCACGCCGTGTACCAGCTCGCCATCATCTTCACCCTGCTGTTTGTCGGGGAGCTCTTCTTCGACATCGACAGCGGGAGGAAT
GCGCCCCTGCACTCGCCACCCTCAGAGCACTACACCATCATCTTCAACACGTTCGTCATGATGCAGCTCTTTAACGAGATCAACGCCCGCAAGATCCACG
GCGAGAGGAACGTGTTCGACGGCATCTTCAGCAACCCCATCTTCTGCACCATCGTTTTGGGCACTTTCGGGATTCAGATTGTCATCGTCCAGTTTGGCGG
GAAGCCCTTCAGCTGCTCCCCACTATCCACAGAACAGTGGCTCTGGTGCCTGTTTGTTGGTGTTGGGGAGCTGGTCTGGGGACAGGTCATTGCCACCATC
CCCACCAGCCAGCTCAAGTGCCTGAAGGAAGCCGGGCACGGGCCCGGGAAGGACGAGATGACCGACGAGGAGCTGGCCGAAGGCGAGGAAGAGATCGACC
ATGCCGAGCGGGAGCTCCGCAGGGGCCAGATCCTCTGGTTCCGGGGCCTGAACCGGATTCAGACGCAGATCCGGGTGGTGAAAGCGTTCCGTAGCTCGCT
CTATGAAGGCCTGGAGAAACCAGAATCCAAGACCTCCATTCACAACTTCATGGCCACGCCCGAGTTTCTGATCAATGACTACACCCACAACATCCCGCTC
ATTGACGACACGGACGTGGACGAGAACGAGGAGCGCCTCCGGGCCCCCCCGCCCCCGTCCCCCAACCAGAACAACAACGCCATAGACAGCGGCATCTACC
TGACCACGCATGTCACCAAGTCAGCTACCTCTTCAGTGTTTTCCTCCAGTCCCGGGAGCCCGCTCCACAGCGTGGAGACGTCCCTCTAACAAGAACTTGT
CTCAGCACATGCGCACACGCACACTCGGACTCACACGAAGTCACACGCACACATGCACGCACACACACATATGGGGACCTGCACACCTGCAAAACGAGGG
AACAACTAAGGTGGCTGAAGACCTTTCTGGCAGGGCATTTGCAAGGACCCAAATCCATTCAACAAGGGTGCAGCCTGCCACAGGCTCCTCATCCGGACTG
AGGAAGACGAGGACAGGGAGGAGGAAAAGGAGGAAGAGGAGGACAAAAAGGGGGAGGAGAAGGTTCTTCGTCCAAAGGAGGAAGGAGAAGAAGTAGAAAG
TGCGAAGAGCTGAGTTCCCCACCTTTTTTTCTATTGATGCTTCTTTTTTAACAAACTACAGTTTTACCGTGTGTTTGCCATTTGAGCTGTGTGGTGGGCA
GGGGGCTGGTTTGGGTTTATGGGGAGCTTTTGTTGCACCCATGCAGGGGCAATCAGATCAGCATCTTCATGCAAAAAAAAAAAAAAAGTTGAGTGCTCTG
CAGGCCTGTGAAGGGTGCCACCTGAGGGAGCCGCCTGCAAGCGGCCCTGCAGCCACAAAGCAACCCGCCCTCTGCAAAAACTAGGCACATCCGCAGTGCG
CATGTGTGTGCGTGCATGCACATATGTGTATGTGTGTGGATCTGTACACACACACGTATATATGGCCAGATGCGTATTTCAATAAGGAACTATTTACTGG
CATGATATTTGCATTCCTCTTATCAGGCATTTTCATTTGGAAATTTCATTATTGAATGTAGCAAGGTTGTAGTTGTTTTTTTTTTTTTTTCAGGGAACTA
GACTGCAAGAATATCTTTCTGGTCAACCCATTTTTGTCCCTCATCACCCCGCCCCCACCTTTCGCTCCTGCCCTCTGCCCGGCCCTACTGAGATTCCCAA
GGAGAAGGCCGAGAGGGGGCGCTCCAGGTCTGGAGCAGGTATAATTGGAGCATTTGCACTGAGACCCCTGCCAGAGAGGAGAAAACCCTTTCAAGGGAAA
TTTTAATCTAAAAGGAAAAAACCAAAATATTGATGAGAAGGAGTCCTCCAGTTAGTGAAAGGGGAGTTTCGTTTTCAGCTTTCTTTGGTTCCTACTCCAA
TTCCACATCCTTCATCCTGGCCATGCCCCCACCTTCAAGAGCATGAAGCACTCTTGGAGTTGTGGGTCCTGCCCAGAGTCCAGAGAGCAGCCTCAGCTGA
GCACAGGTCCGAGGGGGCGGGGGCAGGGCCAAGAGTTCAAAAGAAGCCAATGGAGGGAGAGGGAGCGTCAGAAGCCCGGAGGAGCTGGTGGTGGGAGAAT
GACGGCAGGGACGCAGCCACAGTTCAGACCCTGTCCCCTCAGCACCTGGATGGACTCCCACTGTTTGCTTTGGCAAATGCCGAGGAGTCCTCGGTAGACC
ACCTTGATGTCTGCTGTGACATCAGAGGTGCCACCACCAAAGCACTCTTCCCACCCTAGTCTTTGTGTCCAGCGGCCAAGCTTAAGCCATGAAGTCATGG
ATTTGTGGCTCAGCACCAGGTCCTGAGGGGAGCGTATCCTGGCAGTGTGGGCACCTGGTGGCCAAGCCTCAGTTTCCCCCAAATGAGCAAAGGGGATAAA
GAGGGGCCCGACTTTTGCCACCCTCCTGAGGAAGCCCCTAGGTCCACACAGTGATGCCATGGGGGACCCTTGCCTTCCACACTTGCAGGTGTCACGTTTT
GCAGGGAGGTGTTTGGGCCTTGGGCTCAGCCACTGGGAGACAGTTGGGACCTGAGGGACAGAGGATCGGAATGGAAACCACCAACGTGCACTGGCACCCT
CAGAAGGCTTGTCTCACCTCCACCGGCATCCACACAAAACCAAACAGGAGCAGGCGTCATCCCCACTATTCCCATGAATGCCATGTCACCCCTGAGCAGA
AGCAGTCAAATCTTGGGCAAAAGAATTTCGGTTAGAAAAGAAAATCCCACTTTAAAATGCCAGCTGCAGATAACTCAAAGCCATCCCTTTTTTCTAAAGG
GCACATTGAGAATGTCACCCATTTGTAAACTGTTCCCTGATGTCCTTGTTTAAACGATAATAAGAAAAAGGGCAACTCCATTTGTTGAGGGTCTTTGTGT
TCTTCAATGAGAAATCAAATTTGAGACGTTGAAATTGGAGCTGCGTGCTGCTGCACTCACCGGCTTCTTCTCACTCTCTGTCGTAGACACACCGATAGGA
CCAATGGCCAATAGATATTAAAAGCAAACCCTCACTGCTGCTGTATAAAGTTGCCTAATGTAAATGTCTATTGTTTAGTCCCTAGGTCACCTTTGTGCTG
TGCTGTGGAGTTCAGAAACGGGGTACCATGACCTGGAATCTTTTGCTCTTGTTTTTGCAGTCTTCAAGGCTGGGGGCCCTGTCTCATTGGGAAGCCCCTC
TTTATAAAGCATTATATTACTTGGAATGGCTTGGTCAACTGTGTTCAGTTCATAAATATGTTTTACATTTTTATCTGCCTGTTATAAAGATGAACAAAAA
AACTTAATGAGAAAGATCACAGATACGTAATAATTTAAAGTCTGTAGTTGAATTTCCTAACTTAAAGAATAGACCAAAATTTCTGTGTATAAAAAAAAAT
GAAAGGCTCCTTACATCCTG
  • refseq_ATP2B3.F1 (forward primer)
  • refseq_ATP2B3.R1 (reverse primer)
  • Single exon skipping

Frame 0

VSTLSSFLTAAKPCLGTGTVGGRLSLAVAEPRL
HL*EGLTGSMGDMANSSIEFHPKPQQQRDVPQAG
GFGCTLAELRTLMELRGAEALQKIEEAYGDVSG
LCRRLKTSPTEGLADNTNDLEKRRQIYGQNFIP
PKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLS
FYAPPGEESEACGNVSGGAEDEGEAEAGWIEGA
AILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ
EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLL
PADGVLIQANDLKIDESSLTGESDHVRKSADKD
PMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL
LGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDG
AVAMEMQPLKSAEGGEMEEREKKKANAPKKEKS
VLQGKLTKLAVQIGKAGLVMSAITVIILVLYFV
IETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVL
VVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL
DACETMGNATAICSDKTGTLTTNRMTVVQSYLG
DTHYKEIPAPSALTPKILDLLVHAISINSAYTTK
ILPPEKEGALPRQVGNKTECALLGFVLDLKRDF
QPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPD
GGFRLFSKGASEILLKKCTNILNSNGELRGFRPR
DRDDMVRKIIEPMACDGLRTICIAYRDFSAGQE
PDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAI
RKCQRAGITVRMVTGDNINTARAIAAKCGIIQPG
EDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPK
LRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAV
TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDI
ILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT
VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIM
DTFASLALATEPPTESLLLRKPYGRDKPLISRTM
MKNILGHAVYQLAIIFTLLFVGELFFDIDSGRN
APLHSPPSEHYTIIFNTFVMMQLFNEINARKIH
GERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGG
KPFSCSPLSTEQWLWCLFVGVGELVWGQVIATI
PTSQLKCLKEAGHGPGKDEMTDEELAEGEEEID
HAERELRRGQILWFRGLNRIQTQIRVVKAFRSSL
YEGLEKPESKTSIHNFMATPEFLINDYTHNIPL
IDDTDVDENEERLRAPPPPSPNQNNNAIDSGIY
LTTHVTKSATSSVFSSSPGSPLHSVETSL*QELV
SAHAHTHTRTHTKSHAHMHAHTHMGTCTPAKRG
NN*GG*RPFWQGICKDPNPFNKGAACHRLLIRT
EEDEDREEEKEEEEDKKGEEKVLRPKEEGEEVES
AKS*VPHLFFY*CFFFNKLQFYRVFAI*AVWWA
GGWFGFMGSFCCTHAGAIRSASSCKKKKKVECS
AGL*RVPPEGAACKRPCSHKATRPLQKLGTSAVR
MCVRACTYVYVCGSVHTHVYMARCVFQ*GTIYW
HDICIPLIRHFHLEISLLNVARL*LFFFFFQGT
RLQEYLSGQPIFVPHHPAPTFRSCPLPGPTEIPK
EKAERGRSRSGAGIIGAFALRPLPERRKPFQGK
F*SKRKKPKY**EGVLQLVKGEFRFQLSLVPTP
IPHPSSWPCPHLQEHEALLELWVLPRVQRAASAE
HRSEGAGAGPRVQKKPMEGEGASEARRSWWWEN
DGRDAATVQTLSPQHLDGLPLFALANAEESSVD
HLDVCCDIRGATTKALFPP*SLCPAAKLKP*SHG
FVAQHQVLRGAYPGSVGTWWPSLSFPQMSKGDK
EGPDFCHPPEEAPRSTQ*CHGGPLPSTLAGVTF
CREVFGPWAQPLGDSWDLRDRGSEWKPPTCTGTL
RRLVSPPPASTQNQTGAGVIPTIPMNAMSPLSR
SSQILGKRISVRKENPTLKCQLQITQSHPFFLK
GTLRMSPICKLFPDVLV*TIIRKRATPFVEGLCV
LQ*EIKFETLKLELRAAALTGFFSLSVVDTPIG
PMANRY*KQTLTAAV*SCLM*MSIV*SLGHLCA
VLWSSETGYHDLESFALVFAVFKAGGPVSLGSPS
L*SIILLGMAWSTVFSS*ICFTFLSACYKDEQK
NLMRKITDT**FKVCS*IS*LKE*TKISVYKKK
*KAPYIL

Frame 1

CPRLAAFSPPPNLAWALGPWVAACP*LWLSQDC
TCEKA*QAAWATWPIVPSSSTPSPSSSGMSPRL
EALGARWRSCAPSWSCEGPRRCRRSRRPTGMSAG
SAGG*RPHPQRAWRTTPMTWRSAGRSTGRTSSP
QSNPRPSCSWCGRPCRT*PSSSWRWLPSSLWAS
RSMRRQERRVKPVGMCREAQKMRARPKLAGSRGL
PSCCPSSVWCWSRPSMTGARRSSSEACRAELSR
SRSSRSSGTGSSSRSPWLRWWWGTLPRSSTATC
CQPTACSSRPMTSRSTRAP*RASLTTCASQLTKI
PCCSQALMSWKVLEEWW*PPLA*IPRQASSSRC
LELAERRKRRKIRKASSRMGPWRVARPKLRSRM
VQWPWRCSP*RARRVGRWRSGRRRKPTHPKRRSL
SFRGSSQS*PCRSGKQGW*CLPSPSSSWSSTL*
LRRLSWKAGHGWQSARRSMYNTS*SSSSLVSLC
WSWLSQRACLLLSPSP*LTLSRK**KTTTWCATW
MPARPWATPQPSAPTRRARSPPTV*PWSSPT*E
TPTTKRFRPPAP*PLRSSTSWSMPSPSTVPIPP
KYYLLRRKAPSHARWAIRRSAPCWASSWT*SGTS
SPCASRSRKTSFTKCTPSTRSASP*AQSSACPT
VASASSARGPQRSS*KSAPTS*TAMANSGAFGL
GTGTTW*GRSSSRWLAMASAPSASPTGTSLQARS
PTGTTRMRSWVTSPA*LSWALRTLCGPRSLKLS
ENASVLASQSAW*LGTTSTRPGPSQPNAASSSP
GRTSCA*KGRSSTGGSAMRKAR*NRSGWTRCGPS
*GCWPGRLPPTSTHWSKGLSTAPLVSSGRWWL*
QGMAPTMGRPSRRRTWASPWASQGPTWPRRPPT
SS*PMTTSPASSRQSCGAVTSMTASPSSCSFN*R
SMWWL*SWPSQVPALLRTLLSKPCRCCG*T*SW
THLPLWPWRRSHPQSRCCCGSRTAATSPSSPAP
**RTFWATPCTSSPSSSPCCLSGSSSSTSTAGGM
RPCTRHPQSTTPSSSTRSS*CSSLTRSTPARST
ARGTCSTASSATPSSAPSFWALSGFRLSSSSLA
GSPSAAPHYPQNSGSGACLLVLGSWSGDRSLPPS
PPASSSA*RKPGTGPGRTR*PTRSWPKARKRST
MPSGSSAGARSSGSGA*TGFRRRSGW*KRSVAR
SMKAWRNQNPRPPFTTSWPRPSF*SMTTPTTSRS
LTTRTWTRTRSASGPPRPRPPTRTTTP*TAAST
*PRMSPSQLPLQCFPPVPGARSTAWRRPSNKNL
SQHMRTRTLGLTRSHTHTCTHTHIWGPAHLQNEG
TTKVAEDLSGRAFARTQIHSTRVQPATGSSSGL
RKTRTGRRKRRKRRTKRGRRRFFVQRRKEKK*K
VRRAEFPTFFSIDASFLTNYSFTVCLPFELCGGQ
GAGLGLWGAFVAPMQGQSDQHLHAKKKKKLSAL
QACEGCHLREPPASGPAATKQPALCKN*AHPQC
ACVCVHAHMCMCVDLYTHTYIWPDAYFNKELFTG
MIFAFLLSGIFIWKFHY*M*QGCSCFFFFFREL
DCKNIFLVNPFLSLITPPPPFAPALCPALLRFP
RRRPRGGAPGLEQV*LEHLH*DPCQRGENPFKGN
FNLKGKNQNIDEKESSS**KGSFVFSFLWFLLQ
FHILHPGHAPTFKSMKHSWSCGSCPESREQPQL
STGPRGRGQGQEFKRSQWRERERQKPGGAGGGRM
TAGTQPQFRPCPLSTWMDSHCLLWQMPRSPR*T
TLMSAVTSEVPPPKHSSHPSLCVQRPSLSHEVM
DLWLSTRS*GERILAVWAPGGQASVSPK*AKGIK
RGPTFATLLRKPLGPHSDAMGDPCLPHLQVSRF
AGRCLGLGLSHWETVGT*GTEDRNGNHQRALAP
SEGLSHLHRHPHKTKQEQASSPLFP*MPCHP*AE
AVKSWAKEFRLEKKIPL*NASCR*LKAIPFF*R
AH*ECHPFVNCSLMSLFKR**EKGQLHLLRVFV
FFNEKSNLRR*NWSCVLLHSPASSHSLS*THR*D
QWPIDIKSKPSLLLYKVA*CKCLLFSP*VTFVL
CCGVQKRGTMTWNLLLLFLQSSRLGALSHWEAP
LYKALYYLEWLGQLCSVHKYVLHFYLPVIKMNKK
T**ERSQIRNNLKSVVEFPNLKNRPKFLCIKKN
ERLLTS

Frame 2

VHA*QLSHRRQTLPGHWDRGWPPVPSCG*AKIA
LVRRPDRQHGRHGQ*FHRVPPQAPAAAGCPPGW
RLWVHAGGAAHPHGAARGRGAAEDRGGLRGCQR
ALPEAEDLTHRGPGGQHQ*PGEAQADLRAELHPP
KATQDLPAAGVGGPAGRDPHHPGGGCHRLSGPL
VLCAARRGE*SLWECVGRRRR*GRGRSWLDRGG
CHPAVRHLCGAGHGLQ*LEQGEAVPRPAEPN*AG
AEVHGHPERAAPPGPRGCAGGGGHCPGQVRRPA
ASRRRAHPGQ*PQDRRELPDGRV*PRAQVS*QR
SHAALRHSCHGRFWKNGGDRRWREFPDRHHLHAA
WSWRRGGREER*ERQAAGWGHGE*PDQS*EAGW
CSGHGDAAPEERGGWGDGGAGEEESQRTQKGEV
CPSGEAHKASRADRESRAGDVCHHRHHPGPLLCD
*DVCRGRPDMAGRVHAGLCTILREVLHHWCHCA
GRGCPRGPASCCHHLLSLLCQENDERQQPGAPP
GCLRDHGQRHSHLLRQDGHAHHQPYDRGPVLPRR
HPLQRDSGPQRPDP*DPRPPGPCHLHQQCLYHQ
NTTS*EGRRPPTPGGQ*DGVRPAGLRLGPEAGL
PARARADPGRQALQSVHLQLGPQVHEHSHPHARR
WLPPLQQGGLRDPLEKVHQHLEQQWRTPGLSAS
GPGRHGEEDHRADGLRWPPHHLHRLPGLLCRPG
ARLGQRE*GRG*PHLHSCRGH*GPCAARGP*SYP
KMPACWHHSPHGDWGQHQHGPGHRSQMRHHPAR
GGLPVPRREGVQPADPQ*ERRDRTGAAGQGVAQ
AEGAGPVVSHRQAHTGQRDYRQHHW*AAAGGGCD
RGWHQRWAGPQEGGRGLRHGHRRDRRGQGGLRH
HPDR*QLHQHRQGSHVGP*RL*QHLQVPAVSTD
GQCGGCDRGLHRCLHYSGLSSQSRADVVGELDHG
HICLSGPGDGATHRVAAAAEAVRPRQAPHLPHH
DEEHSGPRRVPARHHLHPAVCRGALLRHRQREE
CAPALATLRALHHHLQHVRHDAAL*RDQRPQDPR
REERVRRHLQQPHLLHHRFGHFRDSDCHRPVWR
EALQLLPTIHRTVALVPVCWCWGAGLGTGHCHH
PHQPAQVPEGSRARAREGRDDRRGAGRRRGRDRP
CRAGAPQGPDPLVPGPEPDSDADPGGESVP*LA
L*RPGETRIQDLHSQLHGHARVSDQ*LHPQHPA
H*RHGRGRERGAPPGPPAPVPQPEQQRHRQRHLP
DHACHQVSYLFSVFLQSREPAPQRGDVPLTRTC
LSTCAHAHSDSHEVTRTHARTHTYGDLHTCKTR
EQLRWLKTFLAGHLQGPKSIQQGCSLPQAPHPD*
GRRGQGGGKGGRGGQKGGGEGSSSKGGRRRSRK
CEELSSPPFFLLMLLF*QTTVLPCVCHLSCVVG
RGLVWVYGELLLHPCRGNQISIFMQKKKKS*VLC
RPVKGAT*GSRLQAALQPQSNPPSAKTRHIRSA
HVCACMHICVCVWICTHTRIYGQMRISIRNYLL
A*YLHSSYQAFSFGNFIIECSKVVVVFFFFSGN*
TARISFWSTHFCPSSPRPHLSLLPSARPY*DSQ
GEGREGALQVWSRYNWSICTETPAREEKTLSRE
ILI*KEKTKILMRRSPPVSERGVSFSAFFGSYSN
STSFILAMPPPSRA*STLGVVGPAQSPESSLS*
AQVRGGGGRAKSSKEANGGRGSVRSPEELVVGE
*RQGRSHSSDPVPSAPGWTPTVCFGKCRGVLGRP
P*CLL*HQRCHHQSTLPTLVFVSSGQA*AMKSW
ICGSAPGPEGSVSWQCGHLVAKPQFPPNEQRG*
RGARLLPPS*GSP*VHTVMPWGTLAFHTCRCHVL
QGGVWALGSATGRQLGPEGQRIGMETTNVHWHP
QKACLTSTGIHTKPNRSRRHPHYSHECHVTPEQ
KQSNLGQKNFG*KRKSHFKMPAADNSKPSLFSKG
HIENVTHL*TVP*CPCLNDNKKKGNSIC*GSLC
SSMRNQI*DVEIGAACCCTHRLLLTLCRRHTDR
TNGQ*ILKANPHCCCIKLPNVNVYCLVPRSPLCC
AVEFRNGVP*PGIFCSCFCSLQGWGPCLIGKPL
FIKHYITWNGLVNCVQFINMFYIFICLL*R*TK
KLNEKDHRYVII*SL*LNFLT*RIDQNFCV*KKM
KGSLHP

Sequence NM_021949

GTGTCCACGCTTAGCAGCTTTCTCACCGCCGCCAAACCTTGCCTGGGCACTGGGACCGTGGGTGGCCGCCTGTCCCTAGCTGTGGCTGAGCCAAGATTGC
ACTTGTGAGAAGGCCTGACAGGCAGCATGGGCGACATGGCCAATAGTTCCATCGAGTTCCACCCCAAGCCCCAGCAGCAGCGGGATGTCCCCCAGGCTGG
AGGCTTTGGGTGCACGCTGGCGGAGCTGCGCACCCTCATGGAGCTGCGAGGGGCCGAGGCGCTGCAGAAGATCGAGGAGGCCTACGGGGATGTCAGCGGG
CTCTGCCGGAGGCTGAAGACCTCACCCACAGAGGGCCTGGCGGACAACACCAATGACCTGGAGAAGCGCAGGCAGATCTACGGGCAGAACTTCATCCCCC
CAAAGCAACCCAAGACCTTCCTGCAGCTGGTGTGGGAGGCCCTGCAGGACGTGACCCTCATCATCCTGGAGGTGGCTGCCATCGTCTCTCTGGGCCTCTC
GTTCTATGCGCCGCCAGGAGAGGAGAGTGAAGCCTGTGGGAATGTGTCGGGAGGCGCAGAAGATGAGGGCGAGGCCGAAGCTGGCTGGATCGAGGGGGCT
GCCATCCTGCTGTCCGTCATCTGTGTGGTGCTGGTCACGGCCTTCAATGACTGGAGCAAGGAGAAGCAGTTCCGAGGCCTGCAGAGCCGAATTGAGCAGG
AGCAGAAGTTCACGGTCATCCGGAACGGGCAGCTCCTCCAGGTCCCCGTGGCTGCGCTGGTGGTGGGGGACATTGCCCAGGTCAAGTACGGCGACCTGCT
GCCAGCCGACGGCGTGCTCATCCAGGCCAATGACCTCAAGATCGACGAGAGCTCCCTGACGGGCGAGTCTGACCACGTGCGCAAGTCAGCTGACAAAGAT
CCCATGCTGCTCTCAGGCACTCATGTCATGGAAGGTTCTGGAAGAATGGTGGTGACCGCCGTTGGCGTGAATTCCCAGACAGGCATCATCTTCACGCTGC
TTGGAGCTGGCGGAGAGGAGGAAGAGAAGAAAGATAAGAAAGGCAAGCAGCAGGATGGGGCCATGGAGAGTAGCCAGACCAAAGCTAAGAAGCAGGATGG
TGCAGTGGCCATGGAGATGCAGCCCCTGAAGAGCGCGGAGGGTGGGGAGATGGAGGAGCGGGAGAAGAAGAAAGCCAACGCACCCAAAAAGGAGAAGTCT
GTCCTTCAGGGGAAGCTCACAAAGCTAGCCGTGCAGATCGGGAAAGCAGGGCTGGTGATGTCTGCCATCACCGTCATCATCCTGGTCCTCTACTTTGTGA
TTGAGACGTTTGTCGTGGAAGGCCGGACATGGCTGGCAGAGTGCACGCCGGTCTATGTACAATACTTCGTGAAGTTCTTCATCATTGGTGTCACTGTGCT
GGTCGTGGCTGTCCCAGAGGGCCTGCCTCTTGCTGTCACCATCTCCTTAGCTTACTCTGTCAAGAAAATGATGAAAGACAACAACCTGGTGCGCCACCTG
GATGCCTGCGAGACCATGGGCAACGCCACAGCCATCTGCTCCGACAAGACGGGCACGCTCACCACCAACCGTATGACCGTGGTCCAGTCCTACCTAGGAG
ACACCCACTACAAAGAGATTCCGGCCCCCAGCGCCCTGACCCCTAAGATCCTCGACCTCCTGGTCCATGCCATCTCCATCAACAGTGCCTATACCACCAA
AATACTACCTCCTGAGAAGGAAGGCGCCCTCCCACGCCAGGTGGGCAATAAGACGGAGTGCGCCCTGCTGGGCTTCGTCTTGGACCTGAAGCGGGACTTC
CAGCCCGTGCGCGAGCAGATCCCGGAAGACAAGCTTTACAAAGTGTACACCTTCAACTCGGTCCGCAAGTCCATGAGCACAGTCATCCGCATGCCCGACG
GTGGCTTCCGCCTCTTCAGCAAGGGGGCCTCAGAGATCCTCTTGAAAAAGTGCACCAACATCTTGAACAGCAATGGCGAACTCCGGGGCTTTCGGCCTCG
GGACCGGGACGACATGGTGAGGAAGATCATCGAGCCGATGGCTTGCGATGGCCTCCGCACCATCTGCATCGCCTACCGGGACTTCTCTGCAGGCCAGGAG
CCCGACTGGGACAACGAGAATGAGGTCGTGGGTGACCTCACCTGCATAGCTGTCGTGGGCATTGAGGACCCTGTGCGGCCCGAGGTCCCTGAAGCTATCC
GAAAATGCCAGCGTGCTGGCATCACAGTCCGCATGGTGACTGGGGACAACATCAACACGGCCCGGGCCATCGCAGCCAAATGCGGCATCATCCAGCCCGG
GGAGGACTTCCTGTGCCTAGAAGGGAAGGAGTTCAACCGGCGGATCCGCAATGAGAAAGGCGAGATAGAACAGGAGCGGCTGGACAAGGTGTGGCCCAAG
CTGAGGGTGCTGGCCCGGTCGTCTCCCACCGACAAGCACACACTGGTCAAAGGGATTATCGACAGCACCACTGGTGAGCAGCGGCAGGTGGTGGCTGTGA
CAGGGGATGGCACCAACGATGGGCCGGCCCTCAAGAAGGCGGACGTGGGCTTCGCCATGGGCATCGCAGGGACCGACGTGGCCAAGGAGGCCTCCGACAT
CATCCTGACCGATGACAACTTCACCAGCATCGTCAAGGCAGTCATGTGGGGCCGTAACGTCTATGACAGCATCTCCAAGTTCCTGCAGTTTCAACTGACG
GTCAATGTGGTGGCTGTGATCGTGGCCTTCACAGGTGCCTGCATTACTCAGGACTCTCCTCTCAAAGCCGTGCAGATGTTGTGGGTGAACTTGATCATGG
ACACATTTGCCTCTCTGGCCCTGGCGACGGAGCCACCCACAGAGTCGCTGCTGCTGCGGAAGCCGTACGGCCGCGACAAGCCCCTCATCTCCCGCACCAT
GATGAAGAACATTCTGGGCCACGCCGTGTACCAGCTCGCCATCATCTTCACCCTGCTGTTTGTCGGGGAGCTCTTCTTCGACATCGACAGCGGGAGGAAT
GCGCCCCTGCACTCGCCACCCTCAGAGCACTACACCATCATCTTCAACACGTTCGTCATGATGCAGCTCTTTAACGAGATCAACGCCCGCAAGATCCACG
GCGAGAGGAACGTGTTCGACGGCATCTTCAGCAACCCCATCTTCTGCACCATCGTTTTGGGCACTTTCGGGATTCAGATTGTCATCGTCCAGTTTGGCGG
GAAGCCCTTCAGCTGCTCCCCACTATCCACAGAACAGTGGCTCTGGTGCCTGTTTGTTGGTGTTGGGGAGCTGGTCTGGGGACAGGTCATTGCCACCATC
CCCACCAGCCAGCTCAAGTGCCTGAAGGAAGCCGGGCACGGGCCCGGGAAGGACGAGATGACCGACGAGGAGCTGGCCGAAGGCGAGGAAGAGATCGACC
ATGCCGAGCGGGAGCTCCGCAGGGGCCAGATCCTCTGGTTCCGGGGCCTGAACCGGATTCAGACGCAGATGGAGGTAGTGAGTACCTTCAAGAGAAGCGG
TTCAGTTCAGGGTGCTGTGCGCCGGCGGTCTTCGGTCCTCAGCCAGCTTCATGACGTAACCAATCTTTCTACCCCTACTCACGCAATTCTCTCTGCTGCC
AATCCTACCAGTGCTGCTGGGA
ATCCGGGTGGTGAAAGCGTTCCGTAGCTCGCTCTATGAAGGCCTGGAGAAACCAGAATCCAAGACCTCCATTCACAAC
TTCATGGCCACGCCCGAGTTTCTGATCAATGACTACACCCACAACATCCCGCTCATTGACGACACGGACGTGGACGAGAACGAGGAGCGCCTCCGGGCCC
CCCCGCCCCCGTCCCCCAACCAGAACAACAACGCCATAGACAGCGGCATCTACCTGACCACGCATGTCACCAAGTCAGCTACCTCTTCAGTGTTTTCCTC
CAGTCCCGGGAGCCCGCTCCACAGCGTGGAGACGTCCCTCTAACAAGAACTTGTCTCAGCACATGCGCACACGCACACTCGGACTCACACGAAGTCACAC
GCACACATGCACGCACACACACATATGGGGACCTGCACACCTGCAAAACGAGGGAACAACTAAGGTGGCTGAAGACCTTTCTGGCAGGGCATTTGCAAGG
ACCCAAATCCATTCAACAAGGGTGCAGCCTGCCACAGGCTCCTCATCCGGACTGAGGAAGACGAGGACAGGGAGGAGGAAAAGGAGGAAGAGGAGGACAA
AAAGGGGGAGGAGAAGGTTCTTCGTCCAAAGGAGGAAGGAGAAGAAGTAGAAAGTGCGAAGAGCTGAGTTCCCCACCTTTTTTTCTATTGATGCTTCTTT
TTTAACAAACTACAGTTTTACCGTGTGTTTGCCATTTGAGCTGTGTGGTGGGCAGGGGGCTGGTTTGGGTTTATGGGGAGCTTTTGTTGCACCCATGCAG
GGGCAATCAGATCAGCATCTTCATGCAAAAAAAAAAAAAAAGTTGAGTGCTCTGCAGGCCTGTGAAGGGTGCCACCTGAGGGAGCCGCCTGCAAGCGGCC
CTGCAGCCACAAAGCAACCCGCCCTCTGCAAAAACTAGGCACATCCGCAGTGCGCATGTGTGTGCGTGCATGCACATATGTGTATGTGTGTGGATCTGTA
CACACACACGTATATATGGCCAGATGCGTATTTCAATAAGGAACTATTTACTGGCATGATATTTGCATTCCTCTTATCAGGCATTTTCATTTGGAAATTT
CATTATTGAATGTAGCAAGGTTGTAGTTGTTTTTTTTTTTTTTTCAGGGAACTAGACTGCAAGAATATCTTTCTGGTCAACCCATTTTTGTCCCTCATCA
CCCCGCCCCCACCTTTCGCTCCTGCCCTCTGCCCGGCCCTACTGAGATTCCCAAGGAGAAGGCCGAGAGGGGGCGCTCCAGGTCTGGAGCAGGTATAATT
GGAGCATTTGCACTGAGACCCCTGCCAGAGAGGAGAAAACCCTTTCAAGGGAAATTTTAATCTAAAAGGAAAAAACCAAAATATTGATGAGAAGGAGTCC
TCCAGTTAGTGAAAGGGGAGTTTCGTTTTCAGCTTTCTTTGGTTCCTACTCCAATTCCACATCCTTCATCCTGGCCATGCCCCCACCTTCAAGAGCATGA
AGCACTCTTGGAGTTGTGGGTCCTGCCCAGAGTCCAGAGAGCAGCCTCAGCTGAGCACAGGTCCGAGGGGGCGGGGGCAGGGCCAAGAGTTCAAAAGAAG
CCAATGGAGGGAGAGGGAGCGTCAGAAGCCCGGAGGAGCTGGTGGTGGGAGAATGACGGCAGGGACGCAGCCACAGTTCAGACCCTGTCCCCTCAGCACC
TGGATGGACTCCCACTGTTTGCTTTGGCAAATGCCGAGGAGTCCTCGGTAGACCACCTTGATGTCTGCTGTGACATCAGAGGTGCCACCACCAAAGCACT
CTTCCCACCCTAGTCTTTGTGTCCAGCGGCCAAGCTTAAGCCATGAAGTCATGGATTTGTGGCTCAGCACCAGGTCCTGAGGGGAGCGTATCCTGGCAGT
GTGGGCACCTGGTGGCCAAGCCTCAGTTTCCCCCAAATGAGCAAAGGGGATAAAGAGGGGCCCGACTTTTGCCACCCTCCTGAGGAAGCCCCTAGGTCCA
CACAGTGATGCCATGGGGGACCCTTGCCTTCCACACTTGCAGGTGTCACGTTTTGCAGGGAGGTGTTTGGGCCTTGGGCTCAGCCACTGGGAGACAGTTG
GGACCTGAGGGACAGAGGATCGGAATGGAAACCACCAACGTGCACTGGCACCCTCAGAAGGCTTGTCTCACCTCCACCGGCATCCACACAAAACCAAACA
GGAGCAGGCGTCATCCCCACTATTCCCATGAATGCCATGTCACCCCTGAGCAGAAGCAGTCAAATCTTGGGCAAAAGAATTTCGGTTAGAAAAGAAAATC
CCACTTTAAAATGCCAGCTGCAGATAACTCAAAGCCATCCCTTTTTTCTAAAGGGCACATTGAGAATGTCACCCATTTGTAAACTGTTCCCTGATGTCCT
TGTTTAAACGATAATAAGAAAAAGGGCAACTCCATTTGTTGAGGGTCTTTGTGTTCTTCAATGAGAAATCAAATTTGAGACGTTGAAATTGGAGCTGCGT
GCTGCTGCACTCACCGGCTTCTTCTCACTCTCTGTCGTAGACACACCGATAGGACCAATGGCCAATAGATATTAAAAGCAAACCCTCACTGCTGCTGTAT
AAAGTTGCCTAATGTAAATGTCTATTGTTTAGTCCCTAGGTCACCTTTGTGCTGTGCTGTGGAGTTCAGAAACGGGGTACCATGACCTGGAATCTTTTGC
TCTTGTTTTTGCAGTCTTCAAGGCTGGGGGCCCTGTCTCATTGGGAAGCCCCTCTTTATAAAGCATTATATTACTTGGAATGGCTTGGTCAACTGTGTTC
AGTTCATAAATATGTTTTACATTTTTATCTGCCTGTTATAAAGATGAACAAAAAAACTTAATGAGAAAGATCACAGATACGTAATAATTTAAAGTCTGTA
GTTGAATTTCCTAACTTAAAGAATAGACCAAAATTTCTGTGTATAAAAAAAAATGAAAGGCTCCTTACATCCTG
  • refseq_ATP2B3.F1 (forward primer)
  • refseq_ATP2B3.R1 (reverse primer)
  • Single exon skipping

Frame 0

VSTLSSFLTAAKPCLGTGTVGGRLSLAVAEPRL
HL*EGLTGSMGDMANSSIEFHPKPQQQRDVPQAG
GFGCTLAELRTLMELRGAEALQKIEEAYGDVSG
LCRRLKTSPTEGLADNTNDLEKRRQIYGQNFIP
PKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLS
FYAPPGEESEACGNVSGGAEDEGEAEAGWIEGA
AILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ
EQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLL
PADGVLIQANDLKIDESSLTGESDHVRKSADKD
PMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL
LGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQDG
AVAMEMQPLKSAEGGEMEEREKKKANAPKKEKS
VLQGKLTKLAVQIGKAGLVMSAITVIILVLYFV
IETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVL
VVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL
DACETMGNATAICSDKTGTLTTNRMTVVQSYLG
DTHYKEIPAPSALTPKILDLLVHAISINSAYTTK
ILPPEKEGALPRQVGNKTECALLGFVLDLKRDF
QPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPD
GGFRLFSKGASEILLKKCTNILNSNGELRGFRPR
DRDDMVRKIIEPMACDGLRTICIAYRDFSAGQE
PDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAI
RKCQRAGITVRMVTGDNINTARAIAAKCGIIQPG
EDFLCLEGKEFNRRIRNEKGEIEQERLDKVWPK
LRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAV
TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDI
ILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT
VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIM
DTFASLALATEPPTESLLLRKPYGRDKPLISRTM
MKNILGHAVYQLAIIFTLLFVGELFFDIDSGRN
APLHSPPSEHYTIIFNTFVMMQLFNEINARKIH
GERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGG
KPFSCSPLSTEQWLWCLFVGVGELVWGQVIATI
PTSQLKCLKEAGHGPGKDEMTDEELAEGEEEID
HAERELRRGQILWFRGLNRIQTQMEVVSTFKRSG
SVQGAVRRRSSVLSQLHDVTNLSTPTHAILSAA
NPTSAAG
NPGGESVP*LAL*RPGETRIQDLHSQ
LHGHARVSDQ*LHPQHPAH*RHGRGRERGAPPGP
PAPVPQPEQQRHRQRHLPDHACHQVSYLFSVFL
QSREPAPQRGDVPLTRTCLSTCAHAHSDSHEVT
RTHARTHTYGDLHTCKTREQLRWLKTFLAGHLQG
PKSIQQGCSLPQAPHPD*GRRGQGGGKGGRGGQ
KGGGEGSSSKGGRRRSRKCEELSSPPFFLLMLL
F*QTTVLPCVCHLSCVVGRGLVWVYGELLLHPCR
GNQISIFMQKKKKS*VLCRPVKGAT*GSRLQAA
LQPQSNPPSAKTRHIRSAHVCACMHICVCVWIC
THTRIYGQMRISIRNYLLA*YLHSSYQAFSFGNF
IIECSKVVVVFFFFSGN*TARISFWSTHFCPSS
PRPHLSLLPSARPY*DSQGEGREGALQVWSRYN
WSICTETPAREEKTLSREILI*KEKTKILMRRSP
PVSERGVSFSAFFGSYSNSTSFILAMPPPSRA*
STLGVVGPAQSPESSLS*AQVRGGGGRAKSSKE
ANGGRGSVRSPEELVVGE*RQGRSHSSDPVPSAP
GWTPTVCFGKCRGVLGRPP*CLL*HQRCHHQST
LPTLVFVSSGQA*AMKSWICGSAPGPEGSVSWQ
CGHLVAKPQFPPNEQRG*RGARLLPPS*GSP*VH
TVMPWGTLAFHTCRCHVLQGGVWALGSATGRQL
GPEGQRIGMETTNVHWHPQKACLTSTGIHTKPN
RSRRHPHYSHECHVTPEQKQSNLGQKNFG*KRKS
HFKMPAADNSKPSLFSKGHIENVTHL*TVP*CP
CLNDNKKKGNSIC*GSLCSSMRNQI*DVEIGAA
CCCTHRLLLTLCRRHTDRTNGQ*ILKANPHCCCI
KLPNVNVYCLVPRSPLCCAVEFRNGVP*PGIFC
SCFCSLQGWGPCLIGKPLFIKHYITWNGLVNCV
QFINMFYIFICLL*R*TKKLNEKDHRYVII*SL*
LNFLT*RIDQNFCV*KKMKGSLHP

Frame 1

CPRLAAFSPPPNLAWALGPWVAACP*LWLSQDC
TCEKA*QAAWATWPIVPSSSTPSPSSSGMSPRL
EALGARWRSCAPSWSCEGPRRCRRSRRPTGMSAG
SAGG*RPHPQRAWRTTPMTWRSAGRSTGRTSSP
QSNPRPSCSWCGRPCRT*PSSSWRWLPSSLWAS
RSMRRQERRVKPVGMCREAQKMRARPKLAGSRGL
PSCCPSSVWCWSRPSMTGARRSSSEACRAELSR
SRSSRSSGTGSSSRSPWLRWWWGTLPRSSTATC
CQPTACSSRPMTSRSTRAP*RASLTTCASQLTKI
PCCSQALMSWKVLEEWW*PPLA*IPRQASSSRC
LELAERRKRRKIRKASSRMGPWRVARPKLRSRM
VQWPWRCSP*RARRVGRWRSGRRRKPTHPKRRSL
SFRGSSQS*PCRSGKQGW*CLPSPSSSWSSTL*
LRRLSWKAGHGWQSARRSMYNTS*SSSSLVSLC
WSWLSQRACLLLSPSP*LTLSRK**KTTTWCATW
MPARPWATPQPSAPTRRARSPPTV*PWSSPT*E
TPTTKRFRPPAP*PLRSSTSWSMPSPSTVPIPP
KYYLLRRKAPSHARWAIRRSAPCWASSWT*SGTS
SPCASRSRKTSFTKCTPSTRSASP*AQSSACPT
VASASSARGPQRSS*KSAPTS*TAMANSGAFGL
GTGTTW*GRSSSRWLAMASAPSASPTGTSLQARS
PTGTTRMRSWVTSPA*LSWALRTLCGPRSLKLS
ENASVLASQSAW*LGTTSTRPGPSQPNAASSSP
GRTSCA*KGRSSTGGSAMRKAR*NRSGWTRCGPS
*GCWPGRLPPTSTHWSKGLSTAPLVSSGRWWL*
QGMAPTMGRPSRRRTWASPWASQGPTWPRRPPT
SS*PMTTSPASSRQSCGAVTSMTASPSSCSFN*R
SMWWL*SWPSQVPALLRTLLSKPCRCCG*T*SW
THLPLWPWRRSHPQSRCCCGSRTAATSPSSPAP
**RTFWATPCTSSPSSSPCCLSGSSSSTSTAGGM
RPCTRHPQSTTPSSSTRSS*CSSLTRSTPARST
ARGTCSTASSATPSSAPSFWALSGFRLSSSSLA
GSPSAAPHYPQNSGSGACLLVLGSWSGDRSLPPS
PPASSSA*RKPGTGPGRTR*PTRSWPKARKRST
MPSGSSAGARSSGSGA*TGFRRRWR**VPSREA
VQFRVLCAGGLRSSASFMT*PIFLPLLTQFSLLP
ILPVLLG
IRVVKAFRSSLYEGLEKPESKTSIHN
FMATPEFLINDYTHNIPLIDDTDVDENEERLRA
PPPPSPNQNNNAIDSGIYLTTHVTKSATSSVFSS
SPGSPLHSVETSL*QELVSAHAHTHTRTHTKSH
AHMHAHTHMGTCTPAKRGNN*GG*RPFWQGICK
DPNPFNKGAACHRLLIRTEEDEDREEEKEEEEDK
KGEEKVLRPKEEGEEVESAKS*VPHLFFY*CFF
FNKLQFYRVFAI*AVWWAGGWFGFMGSFCCTHA
GAIRSASSCKKKKKVECSAGL*RVPPEGAACKRP
CSHKATRPLQKLGTSAVRMCVRACTYVYVCGSV
HTHVYMARCVFQ*GTIYWHDICIPLIRHFHLEI
SLLNVARL*LFFFFFQGTRLQEYLSGQPIFVPHH
PAPTFRSCPLPGPTEIPKEKAERGRSRSGAGII
GAFALRPLPERRKPFQGKF*SKRKKPKY**EGV
LQLVKGEFRFQLSLVPTPIPHPSSWPCPHLQEHE
ALLELWVLPRVQRAASAEHRSEGAGAGPRVQKK
PMEGEGASEARRSWWWENDGRDAATVQTLSPQH
LDGLPLFALANAEESSVDHLDVCCDIRGATTKAL
FPP*SLCPAAKLKP*SHGFVAQHQVLRGAYPGS
VGTWWPSLSFPQMSKGDKEGPDFCHPPEEAPRS
TQ*CHGGPLPSTLAGVTFCREVFGPWAQPLGDSW
DLRDRGSEWKPPTCTGTLRRLVSPPPASTQNQT
GAGVIPTIPMNAMSPLSRSSQILGKRISVRKEN
PTLKCQLQITQSHPFFLKGTLRMSPICKLFPDVL
V*TIIRKRATPFVEGLCVLQ*EIKFETLKLELR
AAALTGFFSLSVVDTPIGPMANRY*KQTLTAAV
*SCLM*MSIV*SLGHLCAVLWSSETGYHDLESFA
LVFAVFKAGGPVSLGSPSL*SIILLGMAWSTVF
SS*ICFTFLSACYKDEQKNLMRKITDT**FKVC
S*IS*LKE*TKISVYKKK*KAPYIL

Frame 2

VHA*QLSHRRQTLPGHWDRGWPPVPSCG*AKIA
LVRRPDRQHGRHGQ*FHRVPPQAPAAAGCPPGW
RLWVHAGGAAHPHGAARGRGAAEDRGGLRGCQR
ALPEAEDLTHRGPGGQHQ*PGEAQADLRAELHPP
KATQDLPAAGVGGPAGRDPHHPGGGCHRLSGPL
VLCAARRGE*SLWECVGRRRR*GRGRSWLDRGG
CHPAVRHLCGAGHGLQ*LEQGEAVPRPAEPN*AG
AEVHGHPERAAPPGPRGCAGGGGHCPGQVRRPA
ASRRRAHPGQ*PQDRRELPDGRV*PRAQVS*QR
SHAALRHSCHGRFWKNGGDRRWREFPDRHHLHAA
WSWRRGGREER*ERQAAGWGHGE*PDQS*EAGW
CSGHGDAAPEERGGWGDGGAGEEESQRTQKGEV
CPSGEAHKASRADRESRAGDVCHHRHHPGPLLCD
*DVCRGRPDMAGRVHAGLCTILREVLHHWCHCA
GRGCPRGPASCCHHLLSLLCQENDERQQPGAPP
GCLRDHGQRHSHLLRQDGHAHHQPYDRGPVLPRR
HPLQRDSGPQRPDP*DPRPPGPCHLHQQCLYHQ
NTTS*EGRRPPTPGGQ*DGVRPAGLRLGPEAGL
PARARADPGRQALQSVHLQLGPQVHEHSHPHARR
WLPPLQQGGLRDPLEKVHQHLEQQWRTPGLSAS
GPGRHGEEDHRADGLRWPPHHLHRLPGLLCRPG
ARLGQRE*GRG*PHLHSCRGH*GPCAARGP*SYP
KMPACWHHSPHGDWGQHQHGPGHRSQMRHHPAR
GGLPVPRREGVQPADPQ*ERRDRTGAAGQGVAQ
AEGAGPVVSHRQAHTGQRDYRQHHW*AAAGGGCD
RGWHQRWAGPQEGGRGLRHGHRRDRRGQGGLRH
HPDR*QLHQHRQGSHVGP*RL*QHLQVPAVSTD
GQCGGCDRGLHRCLHYSGLSSQSRADVVGELDHG
HICLSGPGDGATHRVAAAAEAVRPRQAPHLPHH
DEEHSGPRRVPARHHLHPAVCRGALLRHRQREE
CAPALATLRALHHHLQHVRHDAAL*RDQRPQDPR
REERVRRHLQQPHLLHHRFGHFRDSDCHRPVWR
EALQLLPTIHRTVALVPVCWCWGAGLGTGHCHH
PHQPAQVPEGSRARAREGRDDRRGAGRRRGRDRP
CRAGAPQGPDPLVPGPEPDSDADGGSEYLQEKR
FSSGCCAPAVFGPQPAS*RNQSFYPYSRNSLCC
QSYQCCWE
SGW*KRSVARSMKAWRNQNPRPPFTT
SWPRPSF*SMTTPTTSRSLTTRTWTRTRSASGP
PRPRPPTRTTTP*TAAST*PRMSPSQLPLQCFP
PVPGARSTAWRRPSNKNLSQHMRTRTLGLTRSHT
HTCTHTHIWGPAHLQNEGTTKVAEDLSGRAFAR
TQIHSTRVQPATGSSSGLRKTRTGRRKRRKRRT
KRGRRRFFVQRRKEKK*KVRRAEFPTFFSIDASF
LTNYSFTVCLPFELCGGQGAGLGLWGAFVAPMQ
GQSDQHLHAKKKKKLSALQACEGCHLREPPASG
PAATKQPALCKN*AHPQCACVCVHAHMCMCVDLY
THTYIWPDAYFNKELFTGMIFAFLLSGIFIWKF
HY*M*QGCSCFFFFFRELDCKNIFLVNPFLSLI
TPPPPFAPALCPALLRFPRRRPRGGAPGLEQV*L
EHLH*DPCQRGENPFKGNFNLKGKNQNIDEKES
SS**KGSFVFSFLWFLLQFHILHPGHAPTFKSM
KHSWSCGSCPESREQPQLSTGPRGRGQGQEFKRS
QWRERERQKPGGAGGGRMTAGTQPQFRPCPLST
WMDSHCLLWQMPRSPR*TTLMSAVTSEVPPPKH
SSHPSLCVQRPSLSHEVMDLWLSTRS*GERILAV
WAPGGQASVSPK*AKGIKRGPTFATLLRKPLGP
HSDAMGDPCLPHLQVSRFAGRCLGLGLSHWETV
GT*GTEDRNGNHQRALAPSEGLSHLHRHPHKTKQ
EQASSPLFP*MPCHP*AEAVKSWAKEFRLEKKI
PL*NASCR*LKAIPFF*RAH*ECHPFVNCSLMS
LFKR**EKGQLHLLRVFVFFNEKSNLRR*NWSCV
LLHSPASSHSLS*THR*DQWPIDIKSKPSLLLY
KVA*CKCLLFSP*VTFVLCCGVQKRGTMTWNLL
LLFLQSSRLGALSHWEAPLYKALYYLEWLGQLCS
VHKYVLHFYLPVIKMNKKT**ERSQIRNNLKSV
VEFPNLKNRPKFLCIKKNERLLTS

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