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Sequences

Sequence NM_173201

GGCCGGCTGCTCAAGTGGGACGGGGGTCAGAGCTTTGTGGAGGGAAGAAAAACCTGGAGGGGGCAGGAGAGTAAAAAGAAGAAACCCAGGCAGACAGGCA GTTGGACACACTGAGGAAGACCCCCCACGAGTGGGAACCCCCTGGAAGGAACACACCGGCCCCGGCCCCCAGGAAGGGAGCACAATGGAGGCCGCTCATG CTAAAACCACGGAGGAATGTTTGGCCTATTTTGGGGTGAGTGAGACCACGGGCCTCACCCCGGACCAAGTTAAGCGGAATCTGGAGAAATACGGCCTCAA TGAGCTCCCTGCTGAGGAAGGGAAGACCCTGTGGGAGCTGGTGATAGAGCAGTTTGAAGACCTCCTGGTGCGGATTCTCCTCCTGGCCGCATGCATTTCC TTCGTGCTGGCCTGGTTTGAGGAAGGTGAAGAGACCATCACTGCCTTTGTTGAACCCTTTGTCATCCTCTTGATCCTCATTGCCAATGCCATCGTGGGGG TTTGGCAGGAGCGGAACGCAGAGAACGCCATCGAGGCCCTGAAGGAGTATGAGCCAGAGATGGGGAAGGTCTACCGGGCTGACCGCAAGTCAGTGCAAAG GATCAAGGCTCGGGACATCGTCCCTGGGGACATCGTGGAGGTGGCTGTGGGGGACAAAGTCCCTGCAGACATCCGAATCCTCGCCATCAAATCCACCACG CTGCGGGTTGACCAGTCCATCCTGACAGGCGAGTCTGTATCTGTCATCAAACACACGGAGCCCGTTCCTGACCCCCGAGCTGTCAACCAGGACAAGAAGA ACATGCTTTTCTCGGGCACCAACATTGCAGCCGGCAAGGCCTTGGGCATCGTGGCCACCACTGGTGTGGGCACCGAGATTGGGAAGATCCGAGACCAAAT GGCTGCCACAGAACAGGACAAGACCCCCTTGCAGCAGAAGCTGGATGAGTTTGGGGAGCAGCTCTCCAAGGTCATCTCCCTCATCTGTGTGGCTGTCTGG CTTATCAACATTGGCCACTTCAACGACCCCGTCCATGGGGGCTCCTGGTTCCGCGGGGCCATCTACTACTTTAAGATTGCCGTGGCCTTGGCTGTGGCTG CCATCCCCGAAGGTCTTCCTGCAGTCATCACCACCTGCCTGGCCCTGGGTACCCGTCGGATGGCAAAGAAGAATGCCATTGTAAGAAGCTTGCCCTCCGT AGAGACCCTGGGCTGCACCTCTGTCATCTGTTCCGACAAGACAGGCACCCTCACCACCAACCAGATGTCTGTCTGCAAGATGTTTATCATTGACAAGGTG GATGGGGACATCTGCCTCCTGAATGAGTTCTCCATCACCGGCTCCACTTACGCTCCAGAGGGAGAGGTCTTGAAGAATGATAAGCCAGTCCGGCCAGGGC AGTATGACGGGCTGGTGGAGCTGGCCACCATCTGTGCCCTCTGCAATGACTCCTCCTTGGACTTCAACGAGGCCAAAGGTGTCTATGAGAAGGTCGGCGA GGCCACCGAGACAGCACTCACCACCCTGGTGGAGAAGATGAATGTGTTCAACACGGATGTGAGAAGCCTCTCGAAGGTGGAGAGAGCCAACGCCTGCAAC TCGGTGATCCGCCAGCTAATGAAGAAGGAATTCACCCTGGAGTTCTCCCGAGACAGAAAGTCCATGTCTGTCTATTGCTCCCCAGCCAAATCTTCCCGGG CTGCTGTGGGCAACAAGATGTTTGTCAAGGGTGCCCCTGAGGGCGTCATCGACCGCTGTAACTATGTGCGAGTTGGCACCACCCGGGTGCCACTGACGGG GCCGGTGAAGGAAAAGATCATGGCGGTGATCAAGGAGTGGGGCACTGGCCGGGACACCCTGCGCTGCTTGGCCCTGGCCACCCGGGACACCCCCCCGAAG CGAGAGGAAATGGTCCTGGATGACTCTGCCAGGTTCCTGGAGTATGAGACGGACCTGACATTCGTGGGTGTAGTGGGCATGCTGGACCCTCCGCGCAAGG AGGTCACGGGCTCCATCCAGCTGTGCCGTGACGCCGGGATCCGGGTGATCATGATCACTGGGGACAACAAGGGCACAGCCATTGCCATCTGCCGGCGAAT TGGCATCTTTGGGGAGAACGAGGAGGTGGCCGATCGCGCCTACACGGGCCGAGAGTTCGACGACCTGCCCCTGGCTGAACAGCGGGAAGCCTGCCGACGT GCCTGCTGCTTCGCCCGTGTGGAGCCCTCGCACAAGTCCAAGATTGTGGAGTACCTGCAGTCCTACGATGAGATCACAGCCATGACAGGTGATGGCGTCA ATGACGCCCCTGCCCTGAAGAAGGCTGAGATTGGCATTGCCATGGGATCTGGCACTGCCGTGGCCAAGACTGCCTCTGAGATGGTGCTGGCTGACGACAA CTTCTCCACCATCGTAGCTGCTGTGGAGGAGGGCCGCGCCATCTACAACAACATGAAGCAGTTCATCCGCTACCTCATTTCCTCCAACGTGGGCGAGGTG GTCTGTATCTTCCTGACCGCTGCCCTGGGGCTGCCTGAGGCCCTGATCCCGGTGCAGCTGCTATGGGTGAACTTGGTGACCGACGGGCTCCCAGCCACAG CCCTGGGCTTCAACCCACCAGACCTGGACATCATGGACCGCCCCCCCCGGAGCCCCAAGGAGCCCCTCATCAGTGGCTGGCTCTTCTTCCGCTACATGGC AATCGGGGGCTATGTGGGTGCAGCCACCGTGGGAGCAGCTGCCTGGTGGTTCCTGTACGCTGAGGATGGGCCTCATGTCAACTACAGCCAGCTGACTCAC TTCATGCAGTGCACCGAGGACAACACCCACTTTGAGGGCATAGACTGTGAGGTCTTCGAGGCCCCCGAGCCCATGACCATGGCCCTGTCCGTGCTGGTGA CCATCGAGATGTGCAATGCACTGAACAGCCTGTCCGAGAACCAGTCCCTGCTGCGGATGCCACCCTGGGTGAACATCTGGCTGCTGGGCTCCATCTGCCT CTCCATGTCCCTGCACTTCCTCATCCTCTATGTTGACCCCCTGCCGATGATCTTCAAGCTCCGGGCCCTGGACCTCACCCAGTGGCTCATGGTCCTCAAG ATCTCACTGCCAGTCATTGGGCTCGACGAAATCCTCAAGTTCGTTGCTCGGAACTACCTAGAGGATCCAGAAGATGAAAGAAGGAAGTGAGCATCCTTTT GCTCTGTCCTCCCCACCCCGATAGTGACACATCTTCAGGCAGAGCTGTGGCACAGACCCCCGTCCTGTCCCCCACACCCGTGTCATGTGTCTGTTTATAA ACATGTCCCCTTCCCTTTCCTTCCCCCTCGGCCACCCGCCTCCCTCTCAACCTTGTAAATTCCCCTTCCCAACCCCGAGGGGCTTGCAGGGACAAGGCGA CCGACTGCGCTGAGCTGCTTATTTATTGAAAATAAACGACGGAAAAGTCTGGCCTTGCCTCTGTGCAAGCTTGGAGGCCTGGGTCGCCGCTGTG

refseq_ATP2A1.F1 (forward primer)
refseq_ATP2A1.R1 (reverse primer)
Single exon skipping

Frame 0

GRLLKWDGGQSFVEGRKTWRGQESKKKKPRQTG SWTH*GRPPTSGNPLEGTHRPRPPGREHNGGRSC *NHGGMFGLFWGE*DHGPHPGPS*AESGEIRPQ *APC*GREDPVGAGDRAV*RPPGADSPPGRMHF LRAGLV*GR*RDHHCLC*TLCHPLDPHCQCHRGG LAGAERRERHRGPEGV*ARDGEGLPG*PQVSAK DQGSGHRPWGHRGGGCGGQSPCRHPNPRHQIHH AAG*PVHPDRRVCICHQTHGARS*PPSCQPGQEE HAFLGHQHCSRQGLGHRGHHWCGHRDWEDPRPN GCHRTGQDPLAAEAG*VWGAALQGHLPHLCGCL AYQHWPLQRPRPWGLLVPRGHLLL*DCRGLGCGC HPRRSSCSHHHLPGPGYPSDGKEECHCKKLALR RDPGLHLCHLFRQDRHPHHQPDVCLQDVYH*QG GWGHLPPE*VLHHRLHLRSRGRGLEE**ASPARA V*RAGGAGHHLCPLQ*LLLGLQRGQRCL*EGRR GHRDSTHHPGGEDECVQHGCEKPLEGGESQRLQ LGDPPANEEGIHPGVLPRQKVHVCLLLPSQIFPG CCGQQDVCQGCP*GRHRPL*LCASWHHPGATDG AGEGKDHGGDQGVGHWPGHPALLGPGHPGHPPE ARGNGPG*LCQVPGV*DGPDIRGCSGHAGPSAQG GHGLHPAVP*RRDPGDHDHWGQQGHSHCHLPAN WHLWGERGGGRSRLHGPRVRRPAPG*TAGSLPT CLLLRPCGALAQVQDCGVPAVLR*DHSHDR*WRQ *RPCPEEG*DWHCHGIWHCRGQDCL*DGAG*RQ LLHHRSCCGGGPRHLQQHEAVHPLPHFLQRGRG GLYLPDRCPGAA*GPDPGAAAMGELGDRRAPSHS PGLQPTRPGHHGPPPPEPQGAPHQWLALLPLHG NRGLCGCSHRGSSCLVVPVR*GWASCQLQPADS LHAVHRGQHPL*GHRL*GLRGPRAHDHGPVRAGD HRDVQCTEQPVREPVPAADATLGEHLAAGLHLP LHVPALPHPLC*PPADDLQAPGPGPHPVAHGPQ DLTASHWARRNPQVRCSELPRGSRR*KKEVSILL LCPPHPDSDTSSGRAVAQTPVLSPTPVSCVCL* TCPLPFPSPSATRLPLNLVNSPSQPRGACRDKA TDCAELLIY*K*TTEKSGLASVQAWRPGSPL

Frame 1

AGCSSGTGVRALWREEKPGGGRRVKRRNPGRQA VGHTEEDPPRVGTPWKEHTGPGPQEGSTMEAAH AKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLN ELPAEEGKTLWELVIEQFEDLLVRILLLAACIS FVLAWFEEGEETITAFVEPFVILLILIANAIVG VWQERNAENAIEALKEYEPEMGKVYRADRKSVQR IKARDIVPGDIVEVAVGDKVPADIRILAIKSTT LRVDQSILTGESVSVIKHTEPVPDPRAVNQDKK NMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM AATEQDKTPLQQKLDEFGEQLSKVISLICVAVW LINIGHFNDPVHGGSWFRGAIYYFKIAVALAVA AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSV ETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKV DGDICLLNEFSITGSTYAPEGEVLKNDKPVRPG QYDGLVELATICALCNDSSLDFNEAKGVYEKVGE ATETALTTLVEKMNVFNTDVRSLSKVERANACN SVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSR AAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTG PVKEKIMAVIKEWGTGRDTLRCLALATRDTPPK REEMVLDDSARFLEYETDLTFVGVVGMLDPPRK EVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRI GIFGENEEVADRAYTGREFDDLPLAEQREACRR ACCFARVEPSHKSKIVEYLQSYDEITAMTGDGV NDAPALKKAEIGIAMGSGTAVAKTASEMVLADDN FSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEV VCIFLTAALGLPEALIPVQLLWVNLVTDGLPAT ALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMA IGGYVGAATVGAAAWWFLYAEDGPHVNYSQLTH FMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLV TIEMCNALNSLSENQSLLRMPPWVNIWLLGSICL SMSLHFLILYVDPLPMIFKLRALDLTQWLMVLK ISLPVIGLDEILKFVARNYLEDPEDERRK*ASF CSVLPTPIVTHLQAELWHRPPSCPPHPCHVSVYK HVPFPFLPPRPPASLSTL*IPLPNPEGLAGTRR PTALSCLFIENKRRKSLALPLCKLGGLGRRC

Frame 2

PAAQVGRGSELCGGKKNLEGAGE*KEETQADRQ LDTLRKTPHEWEPPGRNTPAPAPRKGAQWRPLM LKPRRNVWPILG*VRPRASPRTKLSGIWRNTAS MSSLLRKGRPCGSW**SSLKTSWCGFSSWPHAFP SCWPGLRKVKRPSLPLLNPLSSS*SSLPMPSWG FGRSGTQRTPSRP*RSMSQRWGRSTGLTASQCK GSRLGTSSLGTSWRWLWGTKSLQTSESSPSNPPR CGLTSPS*QASLYLSSNTRSPFLTPELSTRTRR TCFSRAPTLQPARPWASWPPLVWAPRLGRSETK WLPQNRTRPPCSRSWMSLGSSSPRSSPSSVWLSG LSTLATSTTPSMGAPGSAGPSTTLRLPWPWLWL PSPKVFLQSSPPAWPWVPVGWQRRMPL*EACPP *RPWAAPLSSVPTRQAPSPPTRCLSARCLSLTRW MGTSAS*MSSPSPAPLTLQRERS*RMISQSGQG SMTGWWSWPPSVPSAMTPPWTSTRPKVSMRRSA RPPRQHSPPWWRR*MCSTRM*EASRRWREPTPAT R*SAS**RRNSPWSSPETESPCLSIAPQPNLPG LLWATRCLSRVPLRASSTAVTMCELAPPGCH*R GR*RKRSWR*SRSGALAGTPCAAWPWPPGTPPRS ERKWSWMTLPGSWSMRRT*HSWV*WACWTLRAR RSRAPSSCAVTPGSG*S*SLGTTRAQPLPSAGE LASLGRTRRWPIAPTRAESSTTCPWLNSGKPADV PAASPVWSPRTSPRLWSTCSPTMRSQP*QVMAS MTPLP*RRLRLALPWDLALPWPRLPLRWCWLTT TSPPS*LLWRRAAPSTTT*SSSSATSFPPTWARW SVSS*PLPWGCLRP*SRCSCYG*TW*PTGSQPQ PWASTHQTWTSWTAPPGAPRSPSSVAGSSSATW QSGAMWVQPPWEQLPGGSCTLRMGLMSTTAS*LT SCSAPRTTPTLRA*TVRSSRPPSP*PWPCPCW* PSRCAMH*TACPRTSPCCGCHPG*TSGCWAPSA SPCPCTSSSSMLTPCR*SSSSGPWTSPSGSWSSR SHCQSLGSTKSSSSLLGTT*RIQKMKEGSEHPF ALSSPPR**HIFRQSCGTDPRPVPHTRVMCLFI NMSPSLSFPLGHPPPSQPCKFPFPTPRGLQGQGD RLR*AAYLLKINDGKVWPCLCASLEAWVAAV

Sequence NM_004320

GGCCGGCTGCTCAAGTGGGACGGGGGTCAGAGCTTTGTGGAGGGAAGAAAAACCTGGAGGGGGCAGGAGAGTAAAAAGAAGAAACCCAGGCAGACAGGCA GTTGGACACACTGAGGAAGACCCCCCACGAGTGGGAACCCCCTGGAAGGAACACACCGGCCCCGGCCCCCAGGAAGGGAGCACAATGGAGGCCGCTCATG CTAAAACCACGGAGGAATGTTTGGCCTATTTTGGGGTGAGTGAGACCACGGGCCTCACCCCGGACCAAGTTAAGCGGAATCTGGAGAAATACGGCCTCAA TGAGCTCCCTGCTGAGGAAGGGAAGACCCTGTGGGAGCTGGTGATAGAGCAGTTTGAAGACCTCCTGGTGCGGATTCTCCTCCTGGCCGCATGCATTTCC TTCGTGCTGGCCTGGTTTGAGGAAGGTGAAGAGACCATCACTGCCTTTGTTGAACCCTTTGTCATCCTCTTGATCCTCATTGCCAATGCCATCGTGGGGG TTTGGCAGGAGCGGAACGCAGAGAACGCCATCGAGGCCCTGAAGGAGTATGAGCCAGAGATGGGGAAGGTCTACCGGGCTGACCGCAAGTCAGTGCAAAG GATCAAGGCTCGGGACATCGTCCCTGGGGACATCGTGGAGGTGGCTGTGGGGGACAAAGTCCCTGCAGACATCCGAATCCTCGCCATCAAATCCACCACG CTGCGGGTTGACCAGTCCATCCTGACAGGCGAGTCTGTATCTGTCATCAAACACACGGAGCCCGTTCCTGACCCCCGAGCTGTCAACCAGGACAAGAAGA ACATGCTTTTCTCGGGCACCAACATTGCAGCCGGCAAGGCCTTGGGCATCGTGGCCACCACTGGTGTGGGCACCGAGATTGGGAAGATCCGAGACCAAAT GGCTGCCACAGAACAGGACAAGACCCCCTTGCAGCAGAAGCTGGATGAGTTTGGGGAGCAGCTCTCCAAGGTCATCTCCCTCATCTGTGTGGCTGTCTGG CTTATCAACATTGGCCACTTCAACGACCCCGTCCATGGGGGCTCCTGGTTCCGCGGGGCCATCTACTACTTTAAGATTGCCGTGGCCTTGGCTGTGGCTG CCATCCCCGAAGGTCTTCCTGCAGTCATCACCACCTGCCTGGCCCTGGGTACCCGTCGGATGGCAAAGAAGAATGCCATTGTAAGAAGCTTGCCCTCCGT AGAGACCCTGGGCTGCACCTCTGTCATCTGTTCCGACAAGACAGGCACCCTCACCACCAACCAGATGTCTGTCTGCAAGATGTTTATCATTGACAAGGTG GATGGGGACATCTGCCTCCTGAATGAGTTCTCCATCACCGGCTCCACTTACGCTCCAGAGGGAGAGGTCTTGAAGAATGATAAGCCAGTCCGGCCAGGGC AGTATGACGGGCTGGTGGAGCTGGCCACCATCTGTGCCCTCTGCAATGACTCCTCCTTGGACTTCAACGAGGCCAAAGGTGTCTATGAGAAGGTCGGCGA GGCCACCGAGACAGCACTCACCACCCTGGTGGAGAAGATGAATGTGTTCAACACGGATGTGAGAAGCCTCTCGAAGGTGGAGAGAGCCAACGCCTGCAAC TCGGTGATCCGCCAGCTAATGAAGAAGGAATTCACCCTGGAGTTCTCCCGAGACAGAAAGTCCATGTCTGTCTATTGCTCCCCAGCCAAATCTTCCCGGG CTGCTGTGGGCAACAAGATGTTTGTCAAGGGTGCCCCTGAGGGCGTCATCGACCGCTGTAACTATGTGCGAGTTGGCACCACCCGGGTGCCACTGACGGG GCCGGTGAAGGAAAAGATCATGGCGGTGATCAAGGAGTGGGGCACTGGCCGGGACACCCTGCGCTGCTTGGCCCTGGCCACCCGGGACACCCCCCCGAAG CGAGAGGAAATGGTCCTGGATGACTCTGCCAGGTTCCTGGAGTATGAGACGGACCTGACATTCGTGGGTGTAGTGGGCATGCTGGACCCTCCGCGCAAGG AGGTCACGGGCTCCATCCAGCTGTGCCGTGACGCCGGGATCCGGGTGATCATGATCACTGGGGACAACAAGGGCACAGCCATTGCCATCTGCCGGCGAAT TGGCATCTTTGGGGAGAACGAGGAGGTGGCCGATCGCGCCTACACGGGCCGAGAGTTCGACGACCTGCCCCTGGCTGAACAGCGGGAAGCCTGCCGACGT GCCTGCTGCTTCGCCCGTGTGGAGCCCTCGCACAAGTCCAAGATTGTGGAGTACCTGCAGTCCTACGATGAGATCACAGCCATGACAGGTGATGGCGTCA ATGACGCCCCTGCCCTGAAGAAGGCTGAGATTGGCATTGCCATGGGATCTGGCACTGCCGTGGCCAAGACTGCCTCTGAGATGGTGCTGGCTGACGACAA CTTCTCCACCATCGTAGCTGCTGTGGAGGAGGGCCGCGCCATCTACAACAACATGAAGCAGTTCATCCGCTACCTCATTTCCTCCAACGTGGGCGAGGTG GTCTGTATCTTCCTGACCGCTGCCCTGGGGCTGCCTGAGGCCCTGATCCCGGTGCAGCTGCTATGGGTGAACTTGGTGACCGACGGGCTCCCAGCCACAG CCCTGGGCTTCAACCCACCAGACCTGGACATCATGGACCGCCCCCCCCGGAGCCCCAAGGAGCCCCTCATCAGTGGCTGGCTCTTCTTCCGCTACATGGC AATCGGGGGCTATGTGGGTGCAGCCACCGTGGGAGCAGCTGCCTGGTGGTTCCTGTACGCTGAGGATGGGCCTCATGTCAACTACAGCCAGCTGACTCAC TTCATGCAGTGCACCGAGGACAACACCCACTTTGAGGGCATAGACTGTGAGGTCTTCGAGGCCCCCGAGCCCATGACCATGGCCCTGTCCGTGCTGGTGA CCATCGAGATGTGCAATGCACTGAACAGCCTGTCCGAGAACCAGTCCCTGCTGCGGATGCCACCCTGGGTGAACATCTGGCTGCTGGGCTCCATCTGCCT CTCCATGTCCCTGCACTTCCTCATCCTCTATGTTGACCCCCTGCCGATGATCTTCAAGCTCCGGGCCCTGGACCTCACCCAGTGGCTCATGGTCCTCAAG ATCTCACTGCCAGTCATTGGGCTCGACGAAATCCTCAAGTTCGTTGCTCGGAACTACCTAGAGGGATAACTGTTCCCCCTCCTCCATCTCTGAGCCCGTG TCACAGATCCAGAAGATGAAAGAAGGAAGTGAGCATCCTTTTGCTCTGTCCTCCCCACCCCGATAGTGACACATCTTCAGGCAGAGCTGTGGCACAGACC CCCGTCCTGTCCCCCACACCCGTGTCATGTGTCTGTTTATAAACATGTCCCCTTCCCTTTCCTTCCCCCTCGGCCACCCGCCTCCCTCTCAACCTTGTAA ATTCCCCTTCCCAACCCCGAGGGGCTTGCAGGGACAAGGCGACCGACTGCGCTGAGCTGCTTATTTATTGAAAATAAACGACGGAAAAGTCTGGCCTTGC CTCTGTGCAAGCTTGGAGGCCTGGGTCGCCGCTGTG

refseq_ATP2A1.F1 (forward primer)
refseq_ATP2A1.R1 (reverse primer)
Single exon skipping

Frame 0

GRLLKWDGGQSFVEGRKTWRGQESKKKKPRQTG SWTH*GRPPTSGNPLEGTHRPRPPGREHNGGRSC *NHGGMFGLFWGE*DHGPHPGPS*AESGEIRPQ *APC*GREDPVGAGDRAV*RPPGADSPPGRMHF LRAGLV*GR*RDHHCLC*TLCHPLDPHCQCHRGG LAGAERRERHRGPEGV*ARDGEGLPG*PQVSAK DQGSGHRPWGHRGGGCGGQSPCRHPNPRHQIHH AAG*PVHPDRRVCICHQTHGARS*PPSCQPGQEE HAFLGHQHCSRQGLGHRGHHWCGHRDWEDPRPN GCHRTGQDPLAAEAG*VWGAALQGHLPHLCGCL AYQHWPLQRPRPWGLLVPRGHLLL*DCRGLGCGC HPRRSSCSHHHLPGPGYPSDGKEECHCKKLALR RDPGLHLCHLFRQDRHPHHQPDVCLQDVYH*QG GWGHLPPE*VLHHRLHLRSRGRGLEE**ASPARA V*RAGGAGHHLCPLQ*LLLGLQRGQRCL*EGRR GHRDSTHHPGGEDECVQHGCEKPLEGGESQRLQ LGDPPANEEGIHPGVLPRQKVHVCLLLPSQIFPG CCGQQDVCQGCP*GRHRPL*LCASWHHPGATDG AGEGKDHGGDQGVGHWPGHPALLGPGHPGHPPE ARGNGPG*LCQVPGV*DGPDIRGCSGHAGPSAQG GHGLHPAVP*RRDPGDHDHWGQQGHSHCHLPAN WHLWGERGGGRSRLHGPRVRRPAPG*TAGSLPT CLLLRPCGALAQVQDCGVPAVLR*DHSHDR*WRQ *RPCPEEG*DWHCHGIWHCRGQDCL*DGAG*RQ LLHHRSCCGGGPRHLQQHEAVHPLPHFLQRGRG GLYLPDRCPGAA*GPDPGAAAMGELGDRRAPSHS PGLQPTRPGHHGPPPPEPQGAPHQWLALLPLHG NRGLCGCSHRGSSCLVVPVR*GWASCQLQPADS LHAVHRGQHPL*GHRL*GLRGPRAHDHGPVRAGD HRDVQCTEQPVREPVPAADATLGEHLAAGLHLP LHVPALPHPLC*PPADDLQAPGPGPHPVAHGPQ DLTASHWARRNPQVRCSELPRGITVPPPPSLSPC HRSRR*KKEVSILLLCPPHPDSDTSSGRAVAQT PVLSPTPVSCVCL*TCPLPFPSPSATRLPLNLV NSPSQPRGACRDKATDCAELLIY*K*TTEKSGLA SVQAWRPGSPL

Frame 1

AGCSSGTGVRALWREEKPGGGRRVKRRNPGRQA VGHTEEDPPRVGTPWKEHTGPGPQEGSTMEAAH AKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLN ELPAEEGKTLWELVIEQFEDLLVRILLLAACIS FVLAWFEEGEETITAFVEPFVILLILIANAIVG VWQERNAENAIEALKEYEPEMGKVYRADRKSVQR IKARDIVPGDIVEVAVGDKVPADIRILAIKSTT LRVDQSILTGESVSVIKHTEPVPDPRAVNQDKK NMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM AATEQDKTPLQQKLDEFGEQLSKVISLICVAVW LINIGHFNDPVHGGSWFRGAIYYFKIAVALAVA AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSV ETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKV DGDICLLNEFSITGSTYAPEGEVLKNDKPVRPG QYDGLVELATICALCNDSSLDFNEAKGVYEKVGE ATETALTTLVEKMNVFNTDVRSLSKVERANACN SVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSR AAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTG PVKEKIMAVIKEWGTGRDTLRCLALATRDTPPK REEMVLDDSARFLEYETDLTFVGVVGMLDPPRK EVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRI GIFGENEEVADRAYTGREFDDLPLAEQREACRR ACCFARVEPSHKSKIVEYLQSYDEITAMTGDGV NDAPALKKAEIGIAMGSGTAVAKTASEMVLADDN FSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEV VCIFLTAALGLPEALIPVQLLWVNLVTDGLPAT ALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMA IGGYVGAATVGAAAWWFLYAEDGPHVNYSQLTH FMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLV TIEMCNALNSLSENQSLLRMPPWVNIWLLGSICL SMSLHFLILYVDPLPMIFKLRALDLTQWLMVLK ISLPVIGLDEILKFVARNYLEG*LFPLLHL*AR VTDPEDERRK*ASFCSVLPTPIVTHLQAELWHRP PSCPPHPCHVSVYKHVPFPFLPPRPPASLSTL* IPLPNPEGLAGTRRPTALSCLFIENKRRKSLAL PLCKLGGLGRRC

Frame 2

PAAQVGRGSELCGGKKNLEGAGE*KEETQADRQ LDTLRKTPHEWEPPGRNTPAPAPRKGAQWRPLM LKPRRNVWPILG*VRPRASPRTKLSGIWRNTAS MSSLLRKGRPCGSW**SSLKTSWCGFSSWPHAFP SCWPGLRKVKRPSLPLLNPLSSS*SSLPMPSWG FGRSGTQRTPSRP*RSMSQRWGRSTGLTASQCK GSRLGTSSLGTSWRWLWGTKSLQTSESSPSNPPR CGLTSPS*QASLYLSSNTRSPFLTPELSTRTRR TCFSRAPTLQPARPWASWPPLVWAPRLGRSETK WLPQNRTRPPCSRSWMSLGSSSPRSSPSSVWLSG LSTLATSTTPSMGAPGSAGPSTTLRLPWPWLWL PSPKVFLQSSPPAWPWVPVGWQRRMPL*EACPP *RPWAAPLSSVPTRQAPSPPTRCLSARCLSLTRW MGTSAS*MSSPSPAPLTLQRERS*RMISQSGQG SMTGWWSWPPSVPSAMTPPWTSTRPKVSMRRSA RPPRQHSPPWWRR*MCSTRM*EASRRWREPTPAT R*SAS**RRNSPWSSPETESPCLSIAPQPNLPG LLWATRCLSRVPLRASSTAVTMCELAPPGCH*R GR*RKRSWR*SRSGALAGTPCAAWPWPPGTPPRS ERKWSWMTLPGSWSMRRT*HSWV*WACWTLRAR RSRAPSSCAVTPGSG*S*SLGTTRAQPLPSAGE LASLGRTRRWPIAPTRAESSTTCPWLNSGKPADV PAASPVWSPRTSPRLWSTCSPTMRSQP*QVMAS MTPLP*RRLRLALPWDLALPWPRLPLRWCWLTT TSPPS*LLWRRAAPSTTT*SSSSATSFPPTWARW SVSS*PLPWGCLRP*SRCSCYG*TW*PTGSQPQ PWASTHQTWTSWTAPPGAPRSPSSVAGSSSATW QSGAMWVQPPWEQLPGGSCTLRMGLMSTTAS*LT SCSAPRTTPTLRA*TVRSSRPPSP*PWPCPCW* PSRCAMH*TACPRTSPCCGCHPG*TSGCWAPSA SPCPCTSSSSMLTPCR*SSSSGPWTSPSGSWSSR SHCQSLGSTKSSSSLLGTT*RDNCSPSSISEPV SQIQKMKEGSEHPFALSSPPR**HIFRQSCGTD PRPVPHTRVMCLFINMSPSLSFPLGHPPPSQPCK FPFPTPRGLQGQGDRLR*AAYLLKINDGKVWPC LCASLEAWVAAV