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Sequences

Sequence NM_000382

AGTCCTCCCCCGGCGCCTCCGACTGGCAGTGGGACTCAGCGGGCGTGGAGGTCGCGGCTGAGCGAGCGAGCCCTGGGCGAGTGAATTGTGGCTGTGGGTT
GACGGTGGAGACACCCCCCGGAGGGAGGCGGAGGGAAGGGAGGCGAGGCCTGCACCTGCATGCTTCCCGCCTCCCACTCCCCAGCGCCCCCGGACCGTGC
AGTTCTCTGCAGGACCAGGCCATGGAGCTCGAAGTCCGGCGGGTCCGACAGGCGTTCCTGTCCGGCCGGTCGCGACCTCTGCGGTTTCGGCTGCAGCAGC
TGGAGGCCCTGCGGAGGATGGTGCAGGAGCGCGAGAAGGATATCCTGACGGCCATCGCCGCCGACCTGTGCAAGAGTGAATTCAATGTGTACAGTCAGGA
AGTCATTACTGTCCTTGGGGAAATTGATTTTATGCTTGAGAATCTTCCTGAATGGGTTACTGCTAAACCAGTTAAGAAGAACGTGCTCACCATGCTGGAT
GAGGCCTATATTCAGCCACAGCCTCTGGGAGTGGTGCTGATAATCGGAGCTTGGAATTACCCCTTCGTTCTCACCATTCAGCCACTGATAGGAGCCATCG
CTGCAGGAAATGCTGTGATTATAAAGCCTTCTGAACTGAGTGAAAATACAGCCAAGATCTTGGCAAAGCTTCTCCCTCAGTATTTAGACCAGGATCTCTA
TATTGTTATTAATGGTGGTGTTGAGGAAACCACGGAGCTCCTGAAGCAGCGATTTGACCACATTTTCTATACGGGAAACACTGCGGTTGGCAAAATTGTC
ATGGAAGCTGCTGCCAAGCATCTGACCCCTGTGACTCTTGAACTGGGAGGGAAAAGTCCATGTTATATTGATAAAGATTGTGACCTGGACATTGTTTGCA
GACGCATAACCTGGGGAAAATACATGAATTGTGGCCAAACCTGCATTGCACCCGACTATATTCTCTGTGAAGCATCCCTCCAAAATCAAATTGTATGGAA
GATTAAGGAAACAGTGAAGGAATTTTATGGAGAAAATATAAAAGAGTCTCCTGATTATGAAAGGATCATCAATCTTCGTCATTTTAAGAGGATACTAAGT
TTGCTTGAAGGACAAAAGATAGCTTTTGGTGGGGAGACTGATGAGGCCACACGCTACATAGCCCCAACAGTACTTACCGATGTTGATCCTAAAACCAAGG
TGATGCAAGAAGAAATTTTTGGACCAATTCTTCCAATAGTGCCTGTGAAAAATGTAGATGAGGCCATAAATTTCATAAATGAACGTGAAAAGCCTCTGGC
TCTTTATGTATTTTCGCATAACCATAAGCTCATCAAACGGATGATTGATGAGACATCCAGTGGAGGTGTCACAGGCAATGACGTCATTATGCACTTCACG
CTCAACTCTTTCCCATTTGGAGGAGTGGGTTCCAGTGGGATGGGAGCTTATCACGGAAAACATAGTTTTGATACTTTTTCTCATCAGCGTCCCTGTTTAT
TAAAAAGTTTAAAGAGAGAAGGTGCTAACAAACTCAGATATCCTCCCAACAGCCAGTCAAAGGTGGATTGGGGAAAATTTTTTCTCTTGAAACGGTTCAA
CAAAGAAAAACTCGGTCTCCTGTTGCTCACTTTCCTGGGTATTGTAGCCGCTGTGCTTGTCAAGGCAGAATATTACTGAAGAATGATCCTGTTCAACCTC
CTAGTGCCTCTACTGAATTATTCCTCTTTTAAATGGTTAATGAACCAATAATTTTTAAATCATACCAAAAATAGTAAGAAAATATGCAAACACTCTGTGA
TCAAACTTAAAAGTCATTGCCATTCATCATTAATAAAAGTTGCCATTTCAACTACGTCCCAACATTCCCTAATAGGGTATTCAGGGAACCTGTCTTAAAT
TGTGCTTATCTAAATCTTGGAACTTTGAGCTAGGGGAGGAGAATGTATTAGACTAAATACAAACTGCGGGGTTGTAAGGGAGTCTCAGAACCTCACTGAA
TCCTTCACTCCAGTTAATGGCACTGCTCACTTCCTGCCTCTGCTGCCACCATCACTGTGTGAAGCTTTCAAGAGCTTGGTACTTCCCAGGGCTACCGGCA
GTCCTCTGTAGTCCAGAGAGGTGAGATTAGATCTTCTTGGTTCCCTGTGAGGTTTCAGGCACTAAAACTCTATGTGGGGAAGGGAGGGGTTACTCCTCCT
CCAATGGGACTCAAGGACTTGACCTCCAGGAGTAGGCCCCTGGTCAGAAGTGCCATCTCACCAGTGGTCTTCATTCTTCCTCATTCATTCTTTATCATCC
TGTGTTCTGTTTAGTTGCAACAATCTCTTGTGACTAATGTCACTCAAAGCATCTTGTAAATCCTAGGGCTTCCTGGAAGTTAGTTGCCAAAGTCATGCAA
GCATCACCTGTCATTCTTGTGTTGGAGTTATAGAATTCTACATCTTATAAAACCTAACTGGCATTTAAAAAATACTGTGGCCGGGCGTGGTGGCTCATGC
CTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGAGGATTGCTTGAGTCCAGGAATTTGAGACCAGCCTGGACAACACAGTGAGACCTCATCTCTATCAA
AAAATAAAAATTAGCTAGATGTGGTGGCATGAGCCTGTGTTCCCAGCTGCTTAGGAGGCTGAAGCAGGAGGATTGATTGAGCCTGCGAGGCCAAGGCTGC
AGCAGGCTGTGATTGCACCACTGCACTTCAGCTTGGGCAACAGAGCAAGACCCTGTCTCCGAAACAAATAAAAAATACTGTAATAAAAGTACTTATAAAC
ATACTAATCCTCTTTCAGGACCCTAAAGTTGCAGGTTAGTAGGTCTTCAAGGACAAATCTGTAAGTTTCTTATTTCTGTAGTGCAAGTAAAATTTCACTT
TTTGAAACTATAGAGAGATCCCTTTCTGATTAGCCTACAGAACTTAAAGTGAGGGAACCATTTCCTCTCACAGACAAAGAGGCCTGGGATATTAGGACTT
TGGGGTTTGAGAGCATCATGGGGCAGACAGATGGTGGATGGTCTGGACAAGAAGCGAGTAAGCCACTGCGGTTGGTCATACTGAAGGGAATTGATGGCAA
GAGGATCCCCTGAGCAAGTCAGAAGTTACTCTCATCAGTCGTTCATGGTCACAACCTGAGGTACTCTGCTGAGTGGGCAAGGCTGAAGAAGAGGCCTGTG
GAATGCAGCATTACCTGCTGGACAGAGCAGGGCAGGCAGTTCTATGCCTTGGAGCTCCTGACTGCAGGGACTCTGTCCCCACACTCAAAAAGACTCAGCT
CACTCAATGAGAGAATGTGATTTACTTTATAGAACGTATAATCAACTTTGTTGAATAATTTGTTCTATTAAGGCTGTCTAAAGTATGTGATGTCTTCATC
ATAGTATGAAGTGTTGAAAATTAATAACGAGCCTAGTTTAGGAAAAAGCTGCTTAAAACTGTGGCTCTAAGAGAGTAATCATAAAATACCTTAGATAAAA
TTGCACTATGGAATTTTCATTGAGTATGTTTAAATTATTGGCTTGTCTACTAATACACATCTGCTTCAAAATGAACATATTTCATAAAATTGGCATCAAT
TTTAATGACGCTCCTGGTATGGAACCTCAGATATACCCTATTGGAGACAATCCTTTGATCATAAATTCTCCCCAACTATAAATCATTTTATGTCTTTATC
AT
  • refseq_ALDH3A2.F1 (forward primer)
  • refseq_ALDH3A2.R1 (reverse primer)
  • Single exon skipping

Frame 0

SPPPAPPTGSGTQRAWRSRLSERALGE*IVAVG
*RWRHPPEGGGGKGGEACTCMLPASHSPAPPDRA
VLCRTRPWSSKSGGSDRRSCPAGRDLCGFGCSS
WRPCGGWCRSARRIS*RPSPPTCARVNSMCTVR
KSLLSLGKLILCLRIFLNGLLLNQLRRTCSPCWM
RPIFSHSLWEWC**SELGITPSFSPFSH**EPS
LQEML*L*SLLN*VKIQPRSWQSFSLSI*TRIS
ILLLMVVLRKPRSS*SSDLTTFSIRETLRLAKLS
WKLLPSI*PL*LLNWEGKVHVILIKIVTWTLFA
DA*PGENT*IVAKPALHPTIFSVKHPSKIKLYG
RLRKQ*RNFMEKI*KSLLIMKGSSIFVILRGY*V
CLKDKR*LLVGRLMRPHAT*PQQYLPMLILKPR
*CKKKFLDQFFQ*CL*KM*MRP*IS*MNVKSLW
LFMYFRITISSSNG*LMRHPVEVSQAMTSLCTSR
STLSHLEEWVPVGWELITENIVLILFLISVPVY
*KV*REKVLTNSDILPTASQRWIGENFFS*NGS
TKKNSVSCCSLSWVL*PLCLSRQNITEE*SCSTS
*CLY*IIPLLNG**TNNF*IIPKIVRKYANTL*
SNLKVIAIHH**KLPFQLRPNIP**GIQGTCLK
LCLSKSWNFELGEENVLD*IQTAGL*GSLRTSLN
PSLQLMALLTSCLCCHHHCVKLSRAWYFPGLPA
VLCSPER*D*IFLVPCEVSGTKTLCGEGRGYSS
SNGTQGLDLQE*APGQKCHLTSGLHSSSFILYHP
VFCLVATISCD*CHSKHLVNPRASWKLVAKVMQ
ASPVILVLEL*NSTSYKT*LAFKKYCGRAWWLM
PVIPALWEAEVGGLLESRNLRPAWTTQ*DLISIK
K*KLARCGGMSLCSQLLRRLKQED*LSLRGQGC
SRL*LHHCTSAWATEQDPVSETNKKYCNKSTYK
HTNPLSGP*SCRLVGLQGQICKFLISVVQVKFHF
LKL*RDPFLISLQNLK*GNHFLSQTKRPGILGL
WGLRASWGRQMVDGLDKKRVSHCGWSY*RELMA
RGSPEQVRSYSHQSFMVTT*GTLLSGQG*RRGLW
NAALPAGQSRAGSSMPWSS*LQGLCPHTQKDSA
HSMRECDLLYRTYNQLC*IICSIKAV*SM*CLH
HSMKC*KLITSLV*EKAA*NCGSKRVIIKYLR*N
CTMEFSLSMFKLLACLLIHICFKMNIFHKIGIN
FNDAPGMEPQIYPIGDNPLIINSPQL*IILCLY
H

Frame 1

VLPRRLRLAVGLSGRGGRG*ASEPWASELWLWV
DGGDTPRREAEGREARPAPACFPPPTPQRPRTV
QFSAGPGHGARSPAGPTGVPVRPVATSAVSAAAA
GGPAEDGAGAREGYPDGHRRRPVQE*IQCVQSG
SHYCPWGN*FYA*ESS*MGYC*TS*EERAHHAG
*GLYSATASGSGADNRSLELPLRSHHSATDRSHR
CRKCCDYKAF*TE*KYSQDLGKASPSVFRPGSL
YCY*WWC*GNHGAPEAAI*PHFLYGKHCGWQNC
HGSCCQASDPCDS*TGREKSMLY**RL*PGHCLQ
THNLGKIHELWPNLHCTRLYSL*SIPPKSNCME
D*GNSEGILWRKYKRVS*L*KDHQSSSF*EDTK
FA*RTKDSFWWGD**GHTLHSPNSTYRC*S*NQG
DARRNFWTNSSNSACEKCR*GHKFHK*T*KASG
SLCIFA*P*AHQTDD**DIQWRCHRQ*RHYALH
AQLFPIWRSGFQWDGSLSRKT*F*YFFSSASLFI
KKFKERRC*QTQISSQQPVKGGLGKIFSLETVQ
QRKTRSPVAHFPGYCSRCACQGRILLKNDPVQP
PSASTELFLF*MVNEPIIFKSYQK**ENMQTLCD
QT*KSLPFIINKSCHFNYVPTFPNRVFREPVLN
CAYLNLGTLS*GRRMY*TKYKLRGCKGVSEPH*
ILHSS*WHCSLPASAATITV*SFQELGTSQGYRQ
SSVVQRGEIRSSWFPVRFQALKLYVGKGGVTPP
PMGLKDLTSRSRPLVRSAISPVVFILPHSFFII
LCSV*LQQSLVTNVTQSIL*ILGLPGS*LPKSCK
HHLSFLCWSYRILHLIKPNWHLKNTVAGRGGSC
L*SQHFGRPRWEDCLSPGI*DQPGQHSETSSLS
KNKN*LDVVA*ACVPSCLGG*SRRID*ACEAKAA
AGCDCTTALQLGQQSKTLSPKQIKNTVIKVLIN
ILILFQDPKVAG**VFKDKSVSFLFL*CK*NFT
F*NYREIPF*LAYRT*SEGTISSHRQRGLGY*DF
GV*EHHGADRWWMVWTRSE*ATAVGHTEGN*WQ
EDPLSKSEVTLISRSWSQPEVLC*VGKAEEEAC
GMQHYLLDRAGQAVLCLGAPDCRDSVPTLKKTQL
TQ*ENVIYFIERIINFVE*FVLLRLSKVCDVFI
IV*SVEN**RA*FRKKLLKTVALRE*S*NTLDK
IALWNFH*VCLNYWLVY*YTSASK*TYFIKLASI
LMTLLVWNLRYTLLETIL*S*ILPNYKSFYVFI

Frame 2

SSPGASDWQWDSAGVEVAAERASPGRVNCGCGL
TVETPPGGRRREGRRGLHLHASRLPLPSAPGPC
SSLQDQAMELEVRRVRQAFLSGRSRPLRFRLQQ
LEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLD
EAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAI
AAGNAVIIKPSELSENTAKILAKLLPQYLDQDLY
IVINGGVEETTELLKQRFDHIFYTGNTAVGKIV
MEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVC
RRITWGKYMNCGQTCIAPDYILCEASLQNQIVWK
IKETVKEFYGENIKESPDYERIINLRHFKRILS
LLEGQKIAFGGETDEATRYIAPTVLTDVDPKTK
VMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFT
LNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCL
LKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFN
KEKLGLLLLTFLGIVAAVLVKAEYY*RMILFNL
LVPLLNYSSFKWLMNQ*FLNHTKNSKKICKHSV
IKLKSHCHSSLIKVAISTTSQHSLIGYSGNLS*I
VLI*ILEL*ARGGECIRLNTNCGVVRESQNLTE
SFTPVNGTAHFLPLLPPSLCEAFKSLVLPRATG
SPL*SREVRLDLLGSL*GFRH*NSMWGREGLLLL
QWDSRT*PPGVGPWSEVPSHQWSSFFLIHSLSS
CVLFSCNNLL*LMSLKASCKS*GFLEVSCQSHA
SITCHSCVGVIEFYIL*NLTGI*KILWPGVVAHA
CNPSTLGGRGGRIA*VQEFETSLDNTVRPHLYQ
KIKIS*MWWHEPVFPAA*EAEAGGLIEPARPRL
QQAVIAPLHFSLGNRARPCLRNK*KIL**KYL*T
Y*SSFRTLKLQVSRSSRTNL*VSYFCSASKISL
FETIERSLSD*PTELKVREPFPLTDKEAWDIRT
LGFESIMGQTDGGWSGQEASKPLRLVILKGIDGK
RIP*ASQKLLSSVVHGHNLRYSAEWARLKKRPV
ECSITCWTEQGRQFYALELLTAGTLSPHSKRLS
SLNERM*FTL*NV*STLLNNLFY*GCLKYVMSSS
*YEVLKINNEPSLGKSCLKLWL*ESNHKIP*IK
LHYGIFIEYV*IIGLSTNTHLLQNEHIS*NWHQ
F**RSWYGTSDIPYWRQSFDHKFSPTINHFMSLS

Sequence NM_001031806

AGTCCTCCCCCGGCGCCTCCGACTGGCAGTGGGACTCAGCGGGCGTGGAGGTCGCGGCTGAGCGAGCGAGCCCTGGGCGAGTGAATTGTGGCTGTGGGTT
GACGGTGGAGACACCCCCCGGAGGGAGGCGGAGGGAAGGGAGGCGAGGCCTGCACCTGCATGCTTCCCGCCTCCCACTCCCCAGCGCCCCCGGACCGTGC
AGTTCTCTGCAGGACCAGGCCATGGAGCTCGAAGTCCGGCGGGTCCGACAGGCGTTCCTGTCCGGCCGGTCGCGACCTCTGCGGTTTCGGCTGCAGCAGC
TGGAGGCCCTGCGGAGGATGGTGCAGGAGCGCGAGAAGGATATCCTGACGGCCATCGCCGCCGACCTGTGCAAGAGTGAATTCAATGTGTACAGTCAGGA
AGTCATTACTGTCCTTGGGGAAATTGATTTTATGCTTGAGAATCTTCCTGAATGGGTTACTGCTAAACCAGTTAAGAAGAACGTGCTCACCATGCTGGAT
GAGGCCTATATTCAGCCACAGCCTCTGGGAGTGGTGCTGATAATCGGAGCTTGGAATTACCCCTTCGTTCTCACCATTCAGCCACTGATAGGAGCCATCG
CTGCAGGAAATGCTGTGATTATAAAGCCTTCTGAACTGAGTGAAAATACAGCCAAGATCTTGGCAAAGCTTCTCCCTCAGTATTTAGACCAGGATCTCTA
TATTGTTATTAATGGTGGTGTTGAGGAAACCACGGAGCTCCTGAAGCAGCGATTTGACCACATTTTCTATACGGGAAACACTGCGGTTGGCAAAATTGTC
ATGGAAGCTGCTGCCAAGCATCTGACCCCTGTGACTCTTGAACTGGGAGGGAAAAGTCCATGTTATATTGATAAAGATTGTGACCTGGACATTGTTTGCA
GACGCATAACCTGGGGAAAATACATGAATTGTGGCCAAACCTGCATTGCACCCGACTATATTCTCTGTGAAGCATCCCTCCAAAATCAAATTGTATGGAA
GATTAAGGAAACAGTGAAGGAATTTTATGGAGAAAATATAAAAGAGTCTCCTGATTATGAAAGGATCATCAATCTTCGTCATTTTAAGAGGATACTAAGT
TTGCTTGAAGGACAAAAGATAGCTTTTGGTGGGGAGACTGATGAGGCCACACGCTACATAGCCCCAACAGTACTTACCGATGTTGATCCTAAAACCAAGG
TGATGCAAGAAGAAATTTTTGGACCAATTCTTCCAATAGTGCCTGTGAAAAATGTAGATGAGGCCATAAATTTCATAAATGAACGTGAAAAGCCTCTGGC
TCTTTATGTATTTTCGCATAACCATAAGCTCATCAAACGGATGATTGATGAGACATCCAGTGGAGGTGTCACAGGCAATGACGTCATTATGCACTTCACG
CTCAACTCTTTCCCATTTGGAGGAGTGGGTTCCAGTGGGATGGGAGCTTATCACGGAAAACATAGTTTTGATACTTTTTCTCATCAGCGTCCCTGTTTAT
TAAAAAGTTTAAAGAGAGAAGGTGCTAACAAACTCAGATATCCTCCCAACAGCCAGTCAAAGGTGGATTGGGGAAAATTTTTTCTCTTGAAACGGTTCAA
CAAAGAAAAACTCGGTCTCCTGTTGCTCACTTTCCTGGGTATTGTAGCCGCTGTGCTTGTCAAGAAATACCAAGCTGTGCTGAGGAGAAAGGCCCTGTTG
ATTTTTCTGGTAGTTCACAGACTGCGTTGGTCCAGTAAGCAGAGATGAACACCAGATTTCAAAACCCAGCCCTGTCTGTTAAGAGTGAG
GCAGAATATTA
CTGAAGAATGATCCTGTTCAACCTCCTAGTGCCTCTACTGAATTATTCCTCTTTTAAATGGTTAATGAACCAATAATTTTTAAATCATACCAAAAATAGT
AAGAAAATATGCAAACACTCTGTGATCAAACTTAAAAGTCATTGCCATTCATCATTAATAAAAGTTGCCATTTCAACTACGTCCCAACATTCCCTAATAG
GGTATTCAGGGAACCTGTCTTAAATTGTGCTTATCTAAATCTTGGAACTTTGAGCTAGGGGAGGAGAATGTATTAGACTAAATACAAACTGCGGGGTTGT
AAGGGAGTCTCAGAACCTCACTGAATCCTTCACTCCAGTTAATGGCACTGCTCACTTCCTGCCTCTGCTGCCACCATCACTGTGTGAAGCTTTCAAGAGC
TTGGTACTTCCCAGGGCTACCGGCAGTCCTCTGTAGTCCAGAGAGGTGAGATTAGATCTTCTTGGTTCCCTGTGAGGTTTCAGGCACTAAAACTCTATGT
GGGGAAGGGAGGGGTTACTCCTCCTCCAATGGGACTCAAGGACTTGACCTCCAGGAGTAGGCCCCTGGTCAGAAGTGCCATCTCACCAGTGGTCTTCATT
CTTCCTCATTCATTCTTTATCATCCTGTGTTCTGTTTAGTTGCAACAATCTCTTGTGACTAATGTCACTCAAAGCATCTTGTAAATCCTAGGGCTTCCTG
GAAGTTAGTTGCCAAAGTCATGCAAGCATCACCTGTCATTCTTGTGTTGGAGTTATAGAATTCTACATCTTATAAAACCTAACTGGCATTTAAAAAATAC
TGTGGCCGGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGAGGATTGCTTGAGTCCAGGAATTTGAGACCAGCCTGGACAA
CACAGTGAGACCTCATCTCTATCAAAAAATAAAAATTAGCTAGATGTGGTGGCATGAGCCTGTGTTCCCAGCTGCTTAGGAGGCTGAAGCAGGAGGATTG
ATTGAGCCTGCGAGGCCAAGGCTGCAGCAGGCTGTGATTGCACCACTGCACTTCAGCTTGGGCAACAGAGCAAGACCCTGTCTCCGAAACAAATAAAAAA
TACTGTAATAAAAGTACTTATAAACATACTAATCCTCTTTCAGGACCCTAAAGTTGCAGGTTAGTAGGTCTTCAAGGACAAATCTGTAAGTTTCTTATTT
CTGTAGTGCAAGTAAAATTTCACTTTTTGAAACTATAGAGAGATCCCTTTCTGATTAGCCTACAGAACTTAAAGTGAGGGAACCATTTCCTCTCACAGAC
AAAGAGGCCTGGGATATTAGGACTTTGGGGTTTGAGAGCATCATGGGGCAGACAGATGGTGGATGGTCTGGACAAGAAGCGAGTAAGCCACTGCGGTTGG
TCATACTGAAGGGAATTGATGGCAAGAGGATCCCCTGAGCAAGTCAGAAGTTACTCTCATCAGTCGTTCATGGTCACAACCTGAGGTACTCTGCTGAGTG
GGCAAGGCTGAAGAAGAGGCCTGTGGAATGCAGCATTACCTGCTGGACAGAGCAGGGCAGGCAGTTCTATGCCTTGGAGCTCCTGACTGCAGGGACTCTG
TCCCCACACTCAAAAAGACTCAGCTCACTCAATGAGAGAATGTGATTTACTTTATAGAACGTATAATCAACTTTGTTGAATAATTTGTTCTATTAAGGCT
GTCTAAAGTATGTGATGTCTTCATCATAGTATGAAGTGTTGAAAATTAATAACGAGCCTAGTTTAGGAAAAAGCTGCTTAAAACTGTGGCTCTAAGAGAG
TAATCATAAAATACCTTAGATAAAATTGCACTATGGAATTTTCATTGAGTATGTTTAAATTATTGGCTTGTCTACTAATACACATCTGCTTCAAAATGAA
CATATTTCATAAAATTGGCATCAATTTTAATGACGCTCCTGGTATGGAACCTCAGATATACCCTATTGGAGACAATCCTTTGATCATAAATTCTCCCCAA
CTATAAATCATTTTATGTCTTTATCAT
  • refseq_ALDH3A2.F1 (forward primer)
  • refseq_ALDH3A2.R1 (reverse primer)
  • Single exon skipping

Frame 0

SPPPAPPTGSGTQRAWRSRLSERALGE*IVAVG
*RWRHPPEGGGGKGGEACTCMLPASHSPAPPDRA
VLCRTRPWSSKSGGSDRRSCPAGRDLCGFGCSS
WRPCGGWCRSARRIS*RPSPPTCARVNSMCTVR
KSLLSLGKLILCLRIFLNGLLLNQLRRTCSPCWM
RPIFSHSLWEWC**SELGITPSFSPFSH**EPS
LQEML*L*SLLN*VKIQPRSWQSFSLSI*TRIS
ILLLMVVLRKPRSS*SSDLTTFSIRETLRLAKLS
WKLLPSI*PL*LLNWEGKVHVILIKIVTWTLFA
DA*PGENT*IVAKPALHPTIFSVKHPSKIKLYG
RLRKQ*RNFMEKI*KSLLIMKGSSIFVILRGY*V
CLKDKR*LLVGRLMRPHAT*PQQYLPMLILKPR
*CKKKFLDQFFQ*CL*KM*MRP*IS*MNVKSLW
LFMYFRITISSSNG*LMRHPVEVSQAMTSLCTSR
STLSHLEEWVPVGWELITENIVLILFLISVPVY
*KV*REKVLTNSDILPTASQRWIGENFFS*NGS
TKKNSVSCCSLSWVL*PLCLSRNTKLC*GERPC*
FFW*FTDCVGPVSRDEHQISKPSPVC*E*
GRIL
LKNDPVQPPSASTELFLF*MVNEPIIFKSYQK*
*ENMQTLCDQT*KSLPFIINKSCHFNYVPTFPNR
VFREPVLNCAYLNLGTLS*GRRMY*TKYKLRGC
KGVSEPH*ILHSS*WHCSLPASAATITV*SFQE
LGTSQGYRQSSVVQRGEIRSSWFPVRFQALKLYV
GKGGVTPPPMGLKDLTSRSRPLVRSAISPVVFI
LPHSFFIILCSV*LQQSLVTNVTQSIL*ILGLP
GS*LPKSCKHHLSFLCWSYRILHLIKPNWHLKNT
VAGRGGSCL*SQHFGRPRWEDCLSPGI*DQPGQ
HSETSSLSKNKN*LDVVA*ACVPSCLGG*SRRI
D*ACEAKAAAGCDCTTALQLGQQSKTLSPKQIKN
TVIKVLINILILFQDPKVAG**VFKDKSVSFLF
L*CK*NFTF*NYREIPF*LAYRT*SEGTISSHR
QRGLGY*DFGV*EHHGADRWWMVWTRSE*ATAVG
HTEGN*WQEDPLSKSEVTLISRSWSQPEVLC*V
GKAEEEACGMQHYLLDRAGQAVLCLGAPDCRDS
VPTLKKTQLTQ*ENVIYFIERIINFVE*FVLLRL
SKVCDVFIIV*SVEN**RA*FRKKLLKTVALRE
*S*NTLDKIALWNFH*VCLNYWLVY*YTSASK*
TYFIKLASILMTLLVWNLRYTLLETIL*S*ILPN
YKSFYVFI

Frame 1

VLPRRLRLAVGLSGRGGRG*ASEPWASELWLWV
DGGDTPRREAEGREARPAPACFPPPTPQRPRTV
QFSAGPGHGARSPAGPTGVPVRPVATSAVSAAAA
GGPAEDGAGAREGYPDGHRRRPVQE*IQCVQSG
SHYCPWGN*FYA*ESS*MGYC*TS*EERAHHAG
*GLYSATASGSGADNRSLELPLRSHHSATDRSHR
CRKCCDYKAF*TE*KYSQDLGKASPSVFRPGSL
YCY*WWC*GNHGAPEAAI*PHFLYGKHCGWQNC
HGSCCQASDPCDS*TGREKSMLY**RL*PGHCLQ
THNLGKIHELWPNLHCTRLYSL*SIPPKSNCME
D*GNSEGILWRKYKRVS*L*KDHQSSSF*EDTK
FA*RTKDSFWWGD**GHTLHSPNSTYRC*S*NQG
DARRNFWTNSSNSACEKCR*GHKFHK*T*KASG
SLCIFA*P*AHQTDD**DIQWRCHRQ*RHYALH
AQLFPIWRSGFQWDGSLSRKT*F*YFFSSASLFI
KKFKERRC*QTQISSQQPVKGGLGKIFSLETVQ
QRKTRSPVAHFPGYCSRCACQEIPSCAEEKGPV
DFSGSSQTALVQ*AEMNTRFQNPALSVKSE
AEYY
*RMILFNLLVPLLNYSSFKWLMNQ*FLNHTKNS
KKICKHSVIKLKSHCHSSLIKVAISTTSQHSLI
GYSGNLS*IVLI*ILEL*ARGGECIRLNTNCGVV
RESQNLTESFTPVNGTAHFLPLLPPSLCEAFKS
LVLPRATGSPL*SREVRLDLLGSL*GFRH*NSM
WGREGLLLLQWDSRT*PPGVGPWSEVPSHQWSSF
FLIHSLSSCVLFSCNNLL*LMSLKASCKS*GFL
EVSCQSHASITCHSCVGVIEFYIL*NLTGI*KI
LWPGVVAHACNPSTLGGRGGRIA*VQEFETSLDN
TVRPHLYQKIKIS*MWWHEPVFPAA*EAEAGGL
IEPARPRLQQAVIAPLHFSLGNRARPCLRNK*K
IL**KYL*TY*SSFRTLKLQVSRSSRTNL*VSYF
CSASKISLFETIERSLSD*PTELKVREPFPLTD
KEAWDIRTLGFESIMGQTDGGWSGQEASKPLRL
VILKGIDGKRIP*ASQKLLSSVVHGHNLRYSAEW
ARLKKRPVECSITCWTEQGRQFYALELLTAGTL
SPHSKRLSSLNERM*FTL*NV*STLLNNLFY*G
CLKYVMSSS*YEVLKINNEPSLGKSCLKLWL*ES
NHKIP*IKLHYGIFIEYV*IIGLSTNTHLLQNE
HIS*NWHQF**RSWYGTSDIPYWRQSFDHKFSP
TINHFMSLS

Frame 2

SSPGASDWQWDSAGVEVAAERASPGRVNCGCGL
TVETPPGGRRREGRRGLHLHASRLPLPSAPGPC
SSLQDQAMELEVRRVRQAFLSGRSRPLRFRLQQ
LEALRRMVQEREKDILTAIAADLCKSEFNVYSQE
VITVLGEIDFMLENLPEWVTAKPVKKNVLTMLD
EAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAI
AAGNAVIIKPSELSENTAKILAKLLPQYLDQDLY
IVINGGVEETTELLKQRFDHIFYTGNTAVGKIV
MEAAAKHLTPVTLELGGKSPCYIDKDCDLDIVC
RRITWGKYMNCGQTCIAPDYILCEASLQNQIVWK
IKETVKEFYGENIKESPDYERIINLRHFKRILS
LLEGQKIAFGGETDEATRYIAPTVLTDVDPKTK
VMQEEIFGPILPIVPVKNVDEAINFINEREKPLA
LYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFT
LNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCL
LKSLKREGANKLRYPPNSQSKVDWGKFFLLKRFN
KEKLGLLLLTFLGIVAAVLVKKYQAVLRRKALL
IFLVVHRLRWSSKQR*TPDFKTQPCLLRVR
QNI
TEE*SCSTS*CLY*IIPLLNG**TNNF*IIPKIV
RKYANTL*SNLKVIAIHH**KLPFQLRPNIP**
GIQGTCLKLCLSKSWNFELGEENVLD*IQTAGL
*GSLRTSLNPSLQLMALLTSCLCCHHHCVKLSRA
WYFPGLPAVLCSPER*D*IFLVPCEVSGTKTLC
GEGRGYSSSNGTQGLDLQE*APGQKCHLTSGLH
SSSFILYHPVFCLVATISCD*CHSKHLVNPRASW
KLVAKVMQASPVILVLEL*NSTSYKT*LAFKKY
CGRAWWLMPVIPALWEAEVGGLLESRNLRPAWT
TQ*DLISIKK*KLARCGGMSLCSQLLRRLKQED*
LSLRGQGCSRL*LHHCTSAWATEQDPVSETNKK
YCNKSTYKHTNPLSGP*SCRLVGLQGQICKFLI
SVVQVKFHFLKL*RDPFLISLQNLK*GNHFLSQT
KRPGILGLWGLRASWGRQMVDGLDKKRVSHCGW
SY*RELMARGSPEQVRSYSHQSFMVTT*GTLLS
GQG*RRGLWNAALPAGQSRAGSSMPWSS*LQGLC
PHTQKDSAHSMRECDLLYRTYNQLC*IICSIKA
V*SM*CLHHSMKC*KLITSLV*EKAA*NCGSKR
VIIKYLR*NCTMEFSLSMFKLLACLLIHICFKMN
IFHKIGINFNDAPGMEPQIYPIGDNPLIINSPQ
L*IILCLYH

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