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Sequences

Sequence NM_170696

CCGCGCGCACAGCCCGCACTGCCCCACGCCGCGGGCTAGGGACACCCGGCCCGCCACCATGACTTCCAGCAAGATAGAGATGCCCGGCGAGGTGAAGGCC
GACCCCGCCGCCCTCATGGCGTCGCTGCACCTCCTGCCGTCGCCCACGCCCAATCTCGAAATTAAGTACACCAAGATCTTTATAAACAACGAGTGGCAGA
ACTCAGAGAGTGGGAGAGTGTTCCCTGTCTATAATCCAGCCACAGGAGAACAGGTGTGTGAAGTTCAAGAAGCAGACAAGGCAGATATAGACAAAGCAGT
GCAGGCAGCCCGCCTGGCTTTCTCTCTTGGTTCAGTGTGGAGAAGGATGGATGCTTCAGAAAGGGGACGTCTGTTGGATAAGCTTGCAGACTTGGTGGAA
CGGGACAGGGCAGTTCTTGCAACCATGGAATCCCTAAATGGTGGCAAACCATTCCTGCAAGCTTTTTATGTGGATTTGCAGGGCGTCATCAAAACCTTTC
GATATTACGCAGGCTGGGCTGATAAAATTCATGGGATGACCATTCCTGTAGATGGAGACTATTTTACCTTTACAAGACATGAACCCATTGGAGTGTGTGG
ACAGATCATCCCATGGAACTTCCCCCTGCTGATGTTTGCCTGGAAAATAGCTCCAGCTTTGTGCTGTGGCAATACAGTAGTTATTAAGCCAGCAGAGCAA
ACACCACTCAGTGCACTCTACATGGGAGCCCTCATCAAGGAGGTTGGAAAGCTTATCCAAGAAGCAGCTGGAAGAAGTAATTTGAAGAGAGTAACTCTGG
AACTTGGAGGCAAAAGTCCTAATATTATTTTTGCTGATGCTGACTTGGACTATGCTGTGGAGCAGGCCCACCAGGGTGTGTTCTTCAATCAAGGTCAGTG
CTGCACTGCAGGCTCTCGCATCTTCGTGGAGGAGTCCATCTATGAGGAGTTTGTGAGAAGAAGCGTGGAGCGGGCCAAGAGGCGCGTAGTGGGGAGTCCC
TTTGACCCCACCACTGAGCAGGGTCCCCAGATTGATAAGAAACAGTACAACAAGATCTTGGAACTCATCCAGAGTGGTGTGGCTGAGGGCGCCAAGCTGG
AATGTGGAGGCAAAGGACTGGGCCGAAAGGGGTTTTTCATTGAGCCCACAGTGTTTTCCAACGTCACTGATGATATGCGGATTGCCAAGGAGGAGATCTT
TGGCCCTGTTCAGGAAATTTTGAGATTTAAGACGATGGATGAAGTTATCGAAAGAGCCAATAACTCAGACTTTGGACTCGTAGCAGCTGTCTTTACTAAT
GACATCAACAAGGCCCTCACAGTGTCTTCTGCAATGCAAGCTGGGACTGTTTGGATCAATTGTTACAATGCCTTAAATGCCCAGAGCCCCTTTGGGGGAT
TCAAGATGTCTGGAAATGGGAGAGAAATGGGAGAATTTGGCTTGCGGGAGTACTCAGAAGTTAAGACGGTGACAGTAAAGATCCCCCAGAAGAACTCCTA
AGAAGGCCAAGAAGGAGGATGAAGCCCAGCCTGCACGTCTGTCCCTCTCTGCTTTCTCTGTAGGGCCCAGCTCTCAGGAATACAAAGTTGAGCCACGGTC
CTTACTTAAAGATTGAAAAGATAACATGTAGGCCAGGCAGGTCACTGCACAACTAAAGCAAACCAGCTGGGTACAGTTTCTTGGCACTCTGTAAGGGGCC
ACCTTAATCATACCAAATATTGGGGAAAGTGGGATAAAGGGAGGAGGAGGAGCTAGCAGACACATCCAGTATCTCCTTCTGGAGCACAGGATGAAATAAG
GGAGCTGTATTATTTCATGTCTTTGTCACAAAGAACTTTCCTCTCAAGGAAAGGTGACCTTTCTCCTGTCTTCATTTTCCTCCTTCCAGGCCCTCCTCGC
TCACCCACCCCTCCCTCTCTTCCAAGGAGATGTCAGCTGAGCTCATTCTGGGGCAGATGTTTGGGCCGGGAACAATTTTTCAAGGTTGTAAAGCCAAATT
ATCATTTCATGTTATCCATTTCTTCAAAGCAAAACATGAAATGGTTTTAGCTAGAGTCAGACCAGAATGAAAATGCCAGGAGCTGGTACACTACAGATGT
AGTAAGAACCTGGGATATTCCTGACCCAATCTGGTTTTCTTTTACCCATAAATAACATGAATGAAAAAAGATTGGGACAATAGAGACTGGAAGTCATCAT
GTGCAGTTCACCGCTTCTGAGCTTGCTGCAGTTTTGGGGTGTGTGTGTATTAGATTCCTTCTCAGTTATTCTGGAATAAGGCAAGGAGTGGGTTGTTTTT
CATAGCTAGATAAGATCTTTTCCAAAGTTTTTCTTAGAACCAACCAAAAAACAATCCGAGTAGGCCCAAGAATTTGATAATGCTGGATGCCTTGCAGACA
TCATTCAGTTTCTAATATTGGGCAACAATTATTATTAAATGAATTATTTCTGTAGTTGGAATCTGTACCTTCTGAACCTCTACACCAATAACTGCTGCAG
GTGTGATTTTGGTCTGTCACACTGTACATCTATCATAATGTGCCCTGTATCTATTGGCAGTGACCTTGGAAAATCTGGCCAAGCCTAGGGGTTTCCTTTT
CCATTTGCCAAGTTCCATTGTGCCAGGACTGCCGTGCTCCACTGAGCTCCTCTGTCACACCCCATTCTTGCCCCTCACTGGGCAGGCCATGGCCTACAGC
TTGCAGGGAGTAAAGCAGGCCCGCCTCCCTTTCTTCCCATCCACATACTCCTCTTCTGCTTTCCAGTGACTCCACCAGTTTGATGTGGGAAGTGTTAGCT
TCCTTTCCTTCTTCCATCCCTTCTTCCATCTTTCCAGCTGTCAAATCCAATCCAGTCTCTAACCTAAATGCAGATCATTTATTTAAAAGTACCAAACATA
ACCCAGAGTATGTGGAATATGGGCAACATATATATAGCCTTCTGTATTTAACGATCTTCTGCTTCTTAACCGTACCAGTTTTCTATTTATAACTCTTATC
TATCCATGATGTTTTAAAGTCTCCACTTGCTGTTATTTACAAACGACAGTGCATTCAGCAGCCCAGTGCCGTGAGCCCTGACAGATGCCGTATTTCTGAG
TGCTTCCATGTGAATGCTGCCCTCCTGTAGCATGTGTCCAAGTGGACATAGCCACTAACCAACTAGTTACCTTTGGACTGCAACAAAAAATGTGAAAATG
AAGATTTATTTCTTTTAATTTACTTAAAAAGAAACCTCTGTGCTAGCAATAAAGCATTTATATTGTGTA
  • refseq_ALDH1A2.F1 (forward primer)
  • refseq_ALDH1A2.R1 (reverse primer)
  • Single exon skipping

Frame 0

PRAQPALPHAAG*GHPARHHDFQQDRDARRGEG
RPRRPHGVAAPPAVAHAQSRN*VHQDLYKQRVAE
LREWESVPCL*SSHRRTGV*SSRSRQGRYRQSS
AGSPPGFLSWFSVEKDGCFRKGTSVG*ACRLGG
TGQGSSCNHGIPKWWQTIPASFLCGFAGRHQNLS
ILRRLG**NSWDDHSCRWRLFYLYKT*THWSVW
TDHPMELPPADVCLENSSSFVLWQYSSY*ASRA
NTTQCTLHGSPHQGGWKAYPRSSWKK*FEESNSG
TWRQKS*YYFC*C*LGLCCGAGPPGCVLQSRSV
LHCRLSHLRGGVHL*GVCEKKRGAGQEARSGES
L*PHH*AGSPD**ETVQQDLGTHPEWCG*GRQAG
MWRQRTGPKGVFH*AHSVFQRH**YADCQGGDL
WPCSGNFEI*DDG*SYRKSQ*LRLWTRSSCLY*
*HQQGPHSVFCNASWDCLDQLLQCLKCPEPLWGI
QDVWKWERNGRIWLAGVLRS*DGDSKDPPEELL
RRPRRRMKPSLHVCPSLLSL*GPALRNTKLSHG
PYLKIEKITCRPGRSLHN*SKPAGYSFLALCKGP
P*SYQILGKVG*REEEELADTSSISFWSTG*NK
GAVLFHVFVTKNFPLKER*PFSCLHFPPSRPSS
LTHPSLSSKEMSAELILGQMFGPGTIFQGCKAKL
SFHVIHFFKAKHEMVLARVRPE*KCQELVHYRC
SKNLGYS*PNLVFFYP*IT*MKKDWDNRDWKSS
CAVHRF*ACCSFGVCVY*IPSQLFWNKARSGLFF
IAR*DLFQSFS*NQPKNNPSRPKNLIMLDALQT
SFSF*YWATIIIK*IISVVGICTF*TSTPITAA
GVILVCHTVHLS*CALYLLAVTLENLAKPRGFLF
HLPSSIVPGLPCSTELLCHTPFLPLTGQAMAYS
LQGVKQARLPFFPSTYSSSAFQ*LHQFDVGSVS
FLSFFHPFFHLSSCQIQSSL*PKCRSFI*KYQT*
PRVCGIWATYI*PSVFNDLLLLNRTSFLFITLI
YP*CFKVSTCCYLQTTVHSAAQCREP*QMPYF*
VLPCECCPPVACVQVDIATNQLVTFGLQQKM*K*
RFISFNLLKKKPLC*Q*SIYIV

Frame 1

RAHSPHCPTPRARDTRPATMTSSKIEMPGEVKA
DPAALMASLHLLPSPTPNLEIKYTKIFINNEWQ
NSESGRVFPVYNPATGEQVCEVQEADKADIDKAV
QAARLAFSLGSVWRRMDASERGRLLDKLADLVE
RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTF
RYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCG
QIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ
TPLSALYMGALIKEVGKLIQEAAGRSNLKRVTL
ELGGKSPNIIFADADLDYAVEQAHQGVFFNQGQC
CTAGSRIFVEESIYEEFVRRSVERAKRRVVGSP
FDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL
ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIF
GPVQEILRFKTMDEVIERANNSDFGLVAAVFTN
DINKALTVSSAMQAGTVWINCYNALNAQSPFGG
FKMSGNGREMGEFGLREYSEVKTVTVKIPQKNS*
EGQEGG*SPACTSVPLCFLCRAQLSGIQS*ATV
LT*RLKR*HVGQAGHCTTKANQLGTVSWHSVRG
HLNHTKYWGKWDKGRRRS*QTHPVSPSGAQDEIR
ELYYFMSLSQRTFLSRKGDLSPVFIFLLPGPPR
SPTPPSLPRRCQLSSFWGRCLGREQFFKVVKPN
YHFMLSISSKQNMKWF*LESDQNENARSWYTTDV
VRTWDIPDPIWFSFTHK*HE*KKIGTIETGSHH
VQFTASELAAVLGCVCIRFLLSYSGIRQGVGCF
S*LDKIFSKVFLRTNQKTIRVGPRI**CWMPCRH
HSVSNIGQQLLLNELFL*LESVPSEPLHQ*LLQ
V*FWSVTLYIYHNVPCIYWQ*PWKIWPSLGVSF
SICQVPLCQDCRAPLSSSVTPHSCPSLGRPWPTA
CRE*SRPASLSSHPHTPLLLSSDSTSLMWEVLA
SFPSSIPSSIFPAVKSNPVSNLNADHLFKSTKH
NPEYVEYGQHIYSLLYLTIFCFLTVPVFYL*LLS
IHDVLKSPLAVIYKRQCIQQPSAVSPDRCRISE
CFHVNAALL*HVSKWT*PLTN*LPLDCNKKCEN
EDLFLLIYLKRNLCASNKAFILC

Frame 2

ARTARTAPRRGLGTPGPPP*LPAR*RCPAR*RP
TPPPSWRRCTSCRRPRPISKLSTPRSL*TTSGR
TQRVGECSLSIIQPQENRCVKFKKQTRQI*TKQ
CRQPAWLSLLVQCGEGWMLQKGDVCWISLQTWWN
GTGQFLQPWNP*MVANHSCKLFMWICRASSKPF
DITQAGLIKFMG*PFL*METILPLQDMNPLECV
DRSSHGTSPC*CLPGK*LQLCAVAIQ*LLSQQSK
HHSVHSTWEPSSRRLESLSKKQLEEVI*RE*LW
NLEAKVLILFLLMLTWTMLWSRPTRVCSSIKVS
AALQALASSWRSPSMRSL*EEAWSGPRGA*WGVP
LTPPLSRVPRLIRNSTTRSWNSSRVVWLRAPSW
NVEAKDWAERGFSLSPQCFPTSLMICGLPRRRS
LALFRKF*DLRRWMKLSKEPITQTLDS*QLSLLM
TSTRPSQCLLQCKLGLFGSIVTMP*MPRAPLGD
SRCLEMGEKWENLACGSTQKLRR*Q*RSPRRTP
KKAKKEDEAQPARLSLSAFSVGPSSQEYKVEPRS
LLKD*KDNM*ARQVTAQLKQTSWVQFLGTL*GA
TLIIPNIGESGIKGGGGASRHIQYLLLEHRMK*
GSCIISCLCHKELSSQGKVTFLLSSFSSFQALLA
HPPLPLFQGDVS*AHSGADVWAGNNFSRL*SQI
IISCYPFLQSKT*NGFS*SQTRMKMPGAGTLQM
**EPGIFLTQSGFLLPINNMNEKRLGQ*RLEVIM
CSSPLLSLLQFWGVCVLDSFSVILE*GKEWVVF
HS*IRSFPKFFLEPTKKQSE*AQEFDNAGCLAD
IIQFLILGNNYY*MNYFCSWNLYLLNLYTNNCCR
CDFGLSHCTSIIMCPVSIGSDLGKSGQA*GFPF
PFAKFHCARTAVLH*APLSHPILAPHWAGHGLQ
LAGSKAGPPPFLPIHILLFCFPVTPPV*CGKC*L
PFLLPSLLPSFQLSNPIQSLT*MQIIYLKVPNI
TQSMWNMGNIYIAFCI*RSSAS*PYQFSIYNSY
LSMMF*SLHLLLFTNDSAFSSPVP*ALTDAVFLS
ASM*MLPSCSMCPSGHSH*PTSYLWTATKNVKM
KIYFF*FT*KETSVLAIKHLYCV

Sequence NM_170697

GAGTGTTTTTCTTCAGTTGTGCCTCTTCCTCTCTAACAGGCAGATATAGACAAAGCAGTGCAGGCAGCCCGCCTGGCTTTCTCTCTTGGTTCAGTGTGGA
GAAGGATGGATGCTTCAGAAAGGGGACGTCTGTTGGATAAGCTTGCAGACTTGGTGGAACGGGACAGGGCAGTTCTTGCAACCATGGAATCCCTAAATGG
TGGCAAACCATTCCTGCAAGCTTTTTATGTGGATTTGCAGGGCGTCATCAAAACCTTTCGATATTACGCAGGCTGGGCTGATAAAATTCATGGGATGACC
ATTCCTGTAGATGGAGACTATTTTACCTTTACAAGACATGAACCCATTGGAGTGTGTGGACAGATCATCCCATGGAACTTCCCCCTGCTGATGTTTGCCT
GGAAAATAGCTCCAGCTTTGTGCTGTGGCAATACAGTAGTTATTAAGCCAGCAGAGCAAACACCACTCAGTGCACTCTACATGGGAGCCCTCATCAAGGA
GGCTGGCTTTCCTCCCGGGGTCATCAATATTTTGCCAGGATATGGGCCAACGGCTGGGGCAGCAATAGCTTCTCACATTGGCATAGACAAGATTGCATTC
ACAGGGTCTACTGAGGTTGGAAAGCTTATCCAAGAAGCAGCTGGAAGAAGTAATTTGAAGAGAGTAACTCTGGAACTTGGAGGCAAAAGTCCTAATATTA
TTTTTGCTGATGCTGACTTGGACTATGCTGTGGAGCAGGCCCACCAGGGTGTGTTCTTCAATCAAGGTCAGTGCTGCACTGCAGGCTCTCGCATCTTCGT
GGAGGAGTCCATCTATGAGGAGTTTGTGAGAAGAAGCGTGGAGCGGGCCAAGAGGCGCGTAGTGGGGAGTCCCTTTGACCCCACCACTGAGCAGGGTCCC
CAGATTGATAAGAAACAGTACAACAAGATCTTGGAACTCATCCAGAGTGGTGTGGCTGAGGGCGCCAAGCTGGAATGTGGAGGCAAAGGACTGGGCCGAA
AGGGGTTTTTCATTGAGCCCACAGTGTTTTCCAACGTCACTGATGATATGCGGATTGCCAAGGAGGAGATCTTTGGCCCTGTTCAGGAAATTTTGAGATT
TAAGACGATGGATGAAGTTATCGAAAGAGCCAATAACTCAGACTTTGGACTCGTAGCAGCTGTCTTTACTAATGACATCAACAAGGCCCTCACAGTGTCT
TCTGCAATGCAAGCTGGGACTGTTTGGATCAATTGTTACAATGCCTTAAATGCCCAGAGCCCCTTTGGGGGATTCAAGATGTCTGGAAATGGGAGAGAAA
TGGGAGAATTTGGCTTGCGGGAGTACTCAGAAGTTAAGACGGTGACAGTAAAGATCCCCCAGAAGAACTCCTAAGAAGGCCAAGAAGGAGGATGAAGCCC
AGCCTGCACGTCTGTCCCTCTCTGCTTTCTCTGTAGGGCCCAGCTCTCAGGAATACAAAGTTGAGCCACGGTCCTTACTTAAAGATTGAAAAGATAACAT
GTAGGCCAGGCAGGTCACTGCACAACTAAAGCAAACCAGCTGGGTACAGTTTCTTGGCACTCTGTAAGGGGCCACCTTAATCATACCAAATATTGGGGAA
AGTGGGATAAAGGGAGGAGGAGGAGCTAGCAGACACATCCAGTATCTCCTTCTGGAGCACAGGATGAAATAAGGGAGCTGTATTATTTCATGTCTTTGTC
ACAAAGAACTTTCCTCTCAAGGAAAGGTGACCTTTCTCCTGTCTTCATTTTCCTCCTTCCAGGCCCTCCTCGCTCACCCACCCCTCCCTCTCTTCCAAGG
AGATGTCAGCTGAGCTCATTCTGGGGCAGATGTTTGGGCCGGGAACAATTTTTCAAGGTTGTAAAGCCAAATTATCATTTCATGTTATCCATTTCTTCAA
AGCAAAACATGAAATGGTTTTAGCTAGAGTCAGACCAGAATGAAAATGCCAGGAGCTGGTACACTACAGATGTAGTAAGAACCTGGGATATTCCTGACCC
AATCTGGTTTTCTTTTACCCATAAATAACATGAATGAAAAAAGATTGGGACAATAGAGACTGGAAGTCATCATGTGCAGTTCACCGCTTCTGAGCTTGCT
GCAGTTTTGGGGTGTGTGTGTATTAGATTCCTTCTCAGTTATTCTGGAATAAGGCAAGGAGTGGGTTGTTTTTCATAGCTAGATAAGATCTTTTCCAAAG
TTTTTCTTAGAACCAACCAAAAAACAATCCGAGTAGGCCCAAGAATTTGATAATGCTGGATGCCTTGCAGACATCATTCAGTTTCTAATATTGGGCAACA
ATTATTATTAAATGAATTATTTCTGTAGTTGGAATCTGTACCTTCTGAACCTCTACACCAATAACTGCTGCAGGTGTGATTTTGGTCTGTCACACTGTAC
ATCTATCATAATGTGCCCTGTATCTATTGGCAGTGACCTTGGAAAATCTGGCCAAGCCTAGGGGTTTCCTTTTCCATTTGCCAAGTTCCATTGTGCCAGG
ACTGCCGTGCTCCACTGAGCTCCTCTGTCACACCCCATTCTTGCCCCTCACTGGGCAGGCCATGGCCTACAGCTTGCAGGGAGTAAAGCAGGCCCGCCTC
CCTTTCTTCCCATCCACATACTCCTCTTCTGCTTTCCAGTGACTCCACCAGTTTGATGTGGGAAGTGTTAGCTTCCTTTCCTTCTTCCATCCCTTCTTCC
ATCTTTCCAGCTGTCAAATCCAATCCAGTCTCTAACCTAAATGCAGATCATTTATTTAAAAGTACCAAACATAACCCAGAGTATGTGGAATATGGGCAAC
ATATATATAGCCTTCTGTATTTAACGATCTTCTGCTTCTTAACCGTACCAGTTTTCTATTTATAACTCTTATCTATCCATGATGTTTTAAAGTCTCCACT
TGCTGTTATTTACAAACGACAGTGCATTCAGCAGCCCAGTGCCGTGAGCCCTGACAGATGCCGTATTTCTGAGTGCTTCCATGTGAATGCTGCCCTCCTG
TAGCATGTGTCCAAGTGGACATAGCCACTAACCAACTAGTTACCTTTGGACTGCAACAAAAAATGTGAAAATGAAGATTTATTTCTTTTAATTTACTTAA
AAAGAAACCTCTGTGCTAGCAATAAAGCATTTATATTGTGTA
  • refseq_ALDH1A2.F1 (forward primer)
  • refseq_ALDH1A2.R1 (reverse primer)
  • Single exon skipping

Frame 0

ECFSSVVPLPL*QADIDKAVQAARLAFSLGSVW
RRMDASERGRLLDKLADLVERDRAVLATMESLNG
GKPFLQAFYVDLQGVIKTFRYYAGWADKIHGMT
IPVDGDYFTFTRHEPIGVCGQIIPWNFPLLMFA
WKIAPALCCGNTVVIKPAEQTPLSALYMGALIKE
AGFPPGVINILPGYGPTAGAAIASHIGIDKIAF
TGSTEVGKLIQEAAGRSNLKRVTLELGGKSPNI
IFADADLDYAVEQAHQGVFFNQGQCCTAGSRIFV
EESIYEEFVRRSVERAKRRVVGSPFDPTTEQGP
QIDKKQYNKILELIQSGVAEGAKLECGGKGLGR
KGFFIEPTVFSNVTDDMRIAKEEIFGPVQEILRF
KTMDEVIERANNSDFGLVAAVFTNDINKALTVS
SAMQAGTVWINCYNALNAQSPFGGFKMSGNGRE
MGEFGLREYSEVKTVTVKIPQKNS*EGQEGG*SP
ACTSVPLCFLCRAQLSGIQS*ATVLT*RLKR*H
VGQAGHCTTKANQLGTVSWHSVRGHLNHTKYWG
KWDKGRRRS*QTHPVSPSGAQDEIRELYYFMSLS
QRTFLSRKGDLSPVFIFLLPGPPRSPTPPSLPR
RCQLSSFWGRCLGREQFFKVVKPNYHFMLSISS
KQNMKWF*LESDQNENARSWYTTDVVRTWDIPDP
IWFSFTHK*HE*KKIGTIETGSHHVQFTASELA
AVLGCVCIRFLLSYSGIRQGVGCFS*LDKIFSK
VFLRTNQKTIRVGPRI**CWMPCRHHSVSNIGQQ
LLLNELFL*LESVPSEPLHQ*LLQV*FWSVTLY
IYHNVPCIYWQ*PWKIWPSLGVSFSICQVPLCQ
DCRAPLSSSVTPHSCPSLGRPWPTACRE*SRPAS
LSSHPHTPLLLSSDSTSLMWEVLASFPSSIPSS
IFPAVKSNPVSNLNADHLFKSTKHNPEYVEYGQ
HIYSLLYLTIFCFLTVPVFYL*LLSIHDVLKSPL
AVIYKRQCIQQPSAVSPDRCRISECFHVNAALL
*HVSKWT*PLTN*LPLDCNKKCENEDLFLLIYL
KRNLCASNKAFILC

Frame 1

SVFLQLCLFLSNRQI*TKQCRQPAWLSLLVQCG
EGWMLQKGDVCWISLQTWWNGTGQFLQPWNP*M
VANHSCKLFMWICRASSKPFDITQAGLIKFMG*P
FL*METILPLQDMNPLECVDRSSHGTSPC*CLP
GK*LQLCAVAIQ*LLSQQSKHHSVHSTWEPSSR
RLAFLPGSSIFCQDMGQRLGQQ*LLTLA*TRLHS
QGLLRLESLSKKQLEEVI*RE*LWNLEAKVLIL
FLLMLTWTMLWSRPTRVCSSIKVSAALQALASS
WRSPSMRSL*EEAWSGPRGA*WGVPLTPPLSRVP
RLIRNSTTRSWNSSRVVWLRAPSWNVEAKDWAE
RGFSLSPQCFPTSLMICGLPRRRSLALFRKF*D
LRRWMKLSKEPITQTLDS*QLSLLMTSTRPSQCL
LQCKLGLFGSIVTMP*MPRAPLGDSRCLEMGEK
WENLACGSTQKLRR*Q*RSPRRTPKKAKKEDEA
QPARLSLSAFSVGPSSQEYKVEPRSLLKD*KDNM
*ARQVTAQLKQTSWVQFLGTL*GATLIIPNIGE
SGIKGGGGASRHIQYLLLEHRMK*GSCIISCLC
HKELSSQGKVTFLLSSFSSFQALLAHPPLPLFQG
DVS*AHSGADVWAGNNFSRL*SQIIISCYPFLQ
SKT*NGFS*SQTRMKMPGAGTLQM**EPGIFLT
QSGFLLPINNMNEKRLGQ*RLEVIMCSSPLLSLL
QFWGVCVLDSFSVILE*GKEWVVFHS*IRSFPK
FFLEPTKKQSE*AQEFDNAGCLADIIQFLILGN
NYY*MNYFCSWNLYLLNLYTNNCCRCDFGLSHCT
SIIMCPVSIGSDLGKSGQA*GFPFPFAKFHCAR
TAVLH*APLSHPILAPHWAGHGLQLAGSKAGPP
PFLPIHILLFCFPVTPPV*CGKC*LPFLLPSLLP
SFQLSNPIQSLT*MQIIYLKVPNITQSMWNMGN
IYIAFCI*RSSAS*PYQFSIYNSYLSMMF*SLH
LLLFTNDSAFSSPVP*ALTDAVFLSASM*MLPSC
SMCPSGHSH*PTSYLWTATKNVKMKIYFF*FT*
KETSVLAIKHLYCV

Frame 2

VFFFSCASSSLTGRYRQSSAGSPPGFLSWFSVE
KDGCFRKGTSVG*ACRLGGTGQGSSCNHGIPKW
WQTIPASFLCGFAGRHQNLSILRRLG**NSWDD
HSCRWRLFYLYKT*THWSVWTDHPMELPPADVCL
ENSSSFVLWQYSSY*ASRANTTQCTLHGSPHQG
GWLSSRGHQYFARIWANGWGSNSFSHWHRQDCI
HRVY*GWKAYPRSSWKK*FEESNSGTWRQKS*YY
FC*C*LGLCCGAGPPGCVLQSRSVLHCRLSHLR
GGVHL*GVCEKKRGAGQEARSGESL*PHH*AGS
PD**ETVQQDLGTHPEWCG*GRQAGMWRQRTGPK
GVFH*AHSVFQRH**YADCQGGDLWPCSGNFEI
*DDG*SYRKSQ*LRLWTRSSCLY**HQQGPHSV
FCNASWDCLDQLLQCLKCPEPLWGIQDVWKWERN
GRIWLAGVLRS*DGDSKDPPEELLRRPRRRMKP
SLHVCPSLLSL*GPALRNTKLSHGPYLKIEKIT
CRPGRSLHN*SKPAGYSFLALCKGPP*SYQILGK
VG*REEEELADTSSISFWSTG*NKGAVLFHVFV
TKNFPLKER*PFSCLHFPPSRPSSLTHPSLSSK
EMSAELILGQMFGPGTIFQGCKAKLSFHVIHFFK
AKHEMVLARVRPE*KCQELVHYRCSKNLGYS*P
NLVFFYP*IT*MKKDWDNRDWKSSCAVHRF*AC
CSFGVCVY*IPSQLFWNKARSGLFFIAR*DLFQS
FS*NQPKNNPSRPKNLIMLDALQTSFSF*YWAT
IIIK*IISVVGICTF*TSTPITAAGVILVCHTV
HLS*CALYLLAVTLENLAKPRGFLFHLPSSIVPG
LPCSTELLCHTPFLPLTGQAMAYSLQGVKQARL
PFFPSTYSSSAFQ*LHQFDVGSVSFLSFFHPFF
HLSSCQIQSSL*PKCRSFI*KYQT*PRVCGIWAT
YI*PSVFNDLLLLNRTSFLFITLIYP*CFKVST
CCYLQTTVHSAAQCREP*QMPYF*VLPCECCPP
VACVQVDIATNQLVTFGLQQKM*K*RFISFNLLK
KKPLC*Q*SIYIV

Sequence NM_003888

CCGCGCGCACAGCCCGCACTGCCCCACGCCGCGGGCTAGGGACACCCGGCCCGCCACCATGACTTCCAGCAAGATAGAGATGCCCGGCGAGGTGAAGGCC
GACCCCGCCGCCCTCATGGCGTCGCTGCACCTCCTGCCGTCGCCCACGCCCAATCTCGAAATTAAGTACACCAAGATCTTTATAAACAACGAGTGGCAGA
ACTCAGAGAGTGGGAGAGTGTTCCCTGTCTATAATCCAGCCACAGGAGAACAGGTGTGTGAAGTTCAAGAAGCAGACAAGGCAGATATAGACAAAGCAGT
GCAGGCAGCCCGCCTGGCTTTCTCTCTTGGTTCAGTGTGGAGAAGGATGGATGCTTCAGAAAGGGGACGTCTGTTGGATAAGCTTGCAGACTTGGTGGAA
CGGGACAGGGCAGTTCTTGCAACCATGGAATCCCTAAATGGTGGCAAACCATTCCTGCAAGCTTTTTATGTGGATTTGCAGGGCGTCATCAAAACCTTTC
GATATTACGCAGGCTGGGCTGATAAAATTCATGGGATGACCATTCCTGTAGATGGAGACTATTTTACCTTTACAAGACATGAACCCATTGGAGTGTGTGG
ACAGATCATCCCATGGAACTTCCCCCTGCTGATGTTTGCCTGGAAAATAGCTCCAGCTTTGTGCTGTGGCAATACAGTAGTTATTAAGCCAGCAGAGCAA
ACACCACTCAGTGCACTCTACATGGGAGCCCTCATCAAGGAGGCTGGCTTTCCTCCCGGGGTCATCAATATTTTGCCAGGATATGGGCCAACGGCTGGGG
CAGCAATAGCTTCTCACATTGGCATAGACAAGATTGCATTCACAGGGTCTACTGAGGTTGGAAAGCTTATCCAAGAAGCAGCTGGAAGAAGTAATTTGAA
GAGAGTAACTCTGGAACTTGGAGGCAAAAGTCCTAATATTATTTTTGCTGATGCTGACTTGGACTATGCTGTGGAGCAGGCCCACCAGGGTGTGTTCTTC
AATCAAGGTCAGTGCTGCACTGCAGGCTCTCGCATCTTCGTGGAGGAGTCCATCTATGAGGAGTTTGTGAGAAGAAGCGTGGAGCGGGCCAAGAGGCGCG
TAGTGGGGAGTCCCTTTGACCCCACCACTGAGCAGGGTCCCCAGATTGATAAGAAACAGTACAACAAGATCTTGGAACTCATCCAGAGTGGTGTGGCTGA
GGGCGCCAAGCTGGAATGTGGAGGCAAAGGACTGGGCCGAAAGGGGTTTTTCATTGAGCCCACAGTGTTTTCCAACGTCACTGATGATATGCGGATTGCC
AAGGAGGAGATCTTTGGCCCTGTTCAGGAAATTTTGAGATTTAAGACGATGGATGAAGTTATCGAAAGAGCCAATAACTCAGACTTTGGACTCGTAGCAG
CTGTCTTTACTAATGACATCAACAAGGCCCTCACAGTGTCTTCTGCAATGCAAGCTGGGACTGTTTGGATCAATTGTTACAATGCCTTAAATGCCCAGAG
CCCCTTTGGGGGATTCAAGATGTCTGGAAATGGGAGAGAAATGGGAGAATTTGGCTTGCGGGAGTACTCAGAAGTTAAGACGGTGACAGTAAAGATCCCC
CAGAAGAACTCCTAAGAAGGCCAAGAAGGAGGATGAAGCCCAGCCTGCACGTCTGTCCCTCTCTGCTTTCTCTGTAGGGCCCAGCTCTCAGGAATACAAA
GTTGAGCCACGGTCCTTACTTAAAGATTGAAAAGATAACATGTAGGCCAGGCAGGTCACTGCACAACTAAAGCAAACCAGCTGGGTACAGTTTCTTGGCA
CTCTGTAAGGGGCCACCTTAATCATACCAAATATTGGGGAAAGTGGGATAAAGGGAGGAGGAGGAGCTAGCAGACACATCCAGTATCTCCTTCTGGAGCA
CAGGATGAAATAAGGGAGCTGTATTATTTCATGTCTTTGTCACAAAGAACTTTCCTCTCAAGGAAAGGTGACCTTTCTCCTGTCTTCATTTTCCTCCTTC
CAGGCCCTCCTCGCTCACCCACCCCTCCCTCTCTTCCAAGGAGATGTCAGCTGAGCTCATTCTGGGGCAGATGTTTGGGCCGGGAACAATTTTTCAAGGT
TGTAAAGCCAAATTATCATTTCATGTTATCCATTTCTTCAAAGCAAAACATGAAATGGTTTTAGCTAGAGTCAGACCAGAATGAAAATGCCAGGAGCTGG
TACACTACAGATGTAGTAAGAACCTGGGATATTCCTGACCCAATCTGGTTTTCTTTTACCCATAAATAACATGAATGAAAAAAGATTGGGACAATAGAGA
CTGGAAGTCATCATGTGCAGTTCACCGCTTCTGAGCTTGCTGCAGTTTTGGGGTGTGTGTGTATTAGATTCCTTCTCAGTTATTCTGGAATAAGGCAAGG
AGTGGGTTGTTTTTCATAGCTAGATAAGATCTTTTCCAAAGTTTTTCTTAGAACCAACCAAAAAACAATCCGAGTAGGCCCAAGAATTTGATAATGCTGG
ATGCCTTGCAGACATCATTCAGTTTCTAATATTGGGCAACAATTATTATTAAATGAATTATTTCTGTAGTTGGAATCTGTACCTTCTGAACCTCTACACC
AATAACTGCTGCAGGTGTGATTTTGGTCTGTCACACTGTACATCTATCATAATGTGCCCTGTATCTATTGGCAGTGACCTTGGAAAATCTGGCCAAGCCT
AGGGGTTTCCTTTTCCATTTGCCAAGTTCCATTGTGCCAGGACTGCCGTGCTCCACTGAGCTCCTCTGTCACACCCCATTCTTGCCCCTCACTGGGCAGG
CCATGGCCTACAGCTTGCAGGGAGTAAAGCAGGCCCGCCTCCCTTTCTTCCCATCCACATACTCCTCTTCTGCTTTCCAGTGACTCCACCAGTTTGATGT
GGGAAGTGTTAGCTTCCTTTCCTTCTTCCATCCCTTCTTCCATCTTTCCAGCTGTCAAATCCAATCCAGTCTCTAACCTAAATGCAGATCATTTATTTAA
AAGTACCAAACATAACCCAGAGTATGTGGAATATGGGCAACATATATATAGCCTTCTGTATTTAACGATCTTCTGCTTCTTAACCGTACCAGTTTTCTAT
TTATAACTCTTATCTATCCATGATGTTTTAAAGTCTCCACTTGCTGTTATTTACAAACGACAGTGCATTCAGCAGCCCAGTGCCGTGAGCCCTGACAGAT
GCCGTATTTCTGAGTGCTTCCATGTGAATGCTGCCCTCCTGTAGCATGTGTCCAAGTGGACATAGCCACTAACCAACTAGTTACCTTTGGACTGCAACAA
AAAATGTGAAAATGAAGATTTATTTCTTTTAATTTACTTAAAAAGAAACCTCTGTGCTAGCAATAAAGCATTTATATTGTGTA
  • refseq_ALDH1A2.F1 (forward primer)
  • refseq_ALDH1A2.R1 (reverse primer)
  • Single exon skipping

Frame 0

PRAQPALPHAAG*GHPARHHDFQQDRDARRGEG
RPRRPHGVAAPPAVAHAQSRN*VHQDLYKQRVAE
LREWESVPCL*SSHRRTGV*SSRSRQGRYRQSS
AGSPPGFLSWFSVEKDGCFRKGTSVG*ACRLGG
TGQGSSCNHGIPKWWQTIPASFLCGFAGRHQNLS
ILRRLG**NSWDDHSCRWRLFYLYKT*THWSVW
TDHPMELPPADVCLENSSSFVLWQYSSY*ASRA
NTTQCTLHGSPHQGGWLSSRGHQYFARIWANGWG
SNSFSHWHRQDCIHRVY*GWKAYPRSSWKK*FE
ESNSGTWRQKS*YYFC*C*LGLCCGAGPPGCVL
QSRSVLHCRLSHLRGGVHL*GVCEKKRGAGQEAR
SGESL*PHH*AGSPD**ETVQQDLGTHPEWCG*
GRQAGMWRQRTGPKGVFH*AHSVFQRH**YADC
QGGDLWPCSGNFEI*DDG*SYRKSQ*LRLWTRSS
CLY**HQQGPHSVFCNASWDCLDQLLQCLKCPE
PLWGIQDVWKWERNGRIWLAGVLRS*DGDSKDP
PEELLRRPRRRMKPSLHVCPSLLSL*GPALRNTK
LSHGPYLKIEKITCRPGRSLHN*SKPAGYSFLA
LCKGPP*SYQILGKVG*REEEELADTSSISFWS
TG*NKGAVLFHVFVTKNFPLKER*PFSCLHFPPS
RPSSLTHPSLSSKEMSAELILGQMFGPGTIFQG
CKAKLSFHVIHFFKAKHEMVLARVRPE*KCQEL
VHYRCSKNLGYS*PNLVFFYP*IT*MKKDWDNRD
WKSSCAVHRF*ACCSFGVCVY*IPSQLFWNKAR
SGLFFIAR*DLFQSFS*NQPKNNPSRPKNLIML
DALQTSFSF*YWATIIIK*IISVVGICTF*TSTP
ITAAGVILVCHTVHLS*CALYLLAVTLENLAKP
RGFLFHLPSSIVPGLPCSTELLCHTPFLPLTGQ
AMAYSLQGVKQARLPFFPSTYSSSAFQ*LHQFDV
GSVSFLSFFHPFFHLSSCQIQSSL*PKCRSFI*
KYQT*PRVCGIWATYI*PSVFNDLLLLNRTSFL
FITLIYP*CFKVSTCCYLQTTVHSAAQCREP*QM
PYF*VLPCECCPPVACVQVDIATNQLVTFGLQQ
KM*K*RFISFNLLKKKPLC*Q*SIYIV

Frame 1

RAHSPHCPTPRARDTRPATMTSSKIEMPGEVKA
DPAALMASLHLLPSPTPNLEIKYTKIFINNEWQ
NSESGRVFPVYNPATGEQVCEVQEADKADIDKAV
QAARLAFSLGSVWRRMDASERGRLLDKLADLVE
RDRAVLATMESLNGGKPFLQAFYVDLQGVIKTF
RYYAGWADKIHGMTIPVDGDYFTFTRHEPIGVCG
QIIPWNFPLLMFAWKIAPALCCGNTVVIKPAEQ
TPLSALYMGALIKEAGFPPGVINILPGYGPTAG
AAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNLK
RVTLELGGKSPNIIFADADLDYAVEQAHQGVFF
NQGQCCTAGSRIFVEESIYEEFVRRSVERAKRR
VVGSPFDPTTEQGPQIDKKQYNKILELIQSGVAE
GAKLECGGKGLGRKGFFIEPTVFSNVTDDMRIA
KEEIFGPVQEILRFKTMDEVIERANNSDFGLVA
AVFTNDINKALTVSSAMQAGTVWINCYNALNAQS
PFGGFKMSGNGREMGEFGLREYSEVKTVTVKIP
QKNS*EGQEGG*SPACTSVPLCFLCRAQLSGIQ
S*ATVLT*RLKR*HVGQAGHCTTKANQLGTVSWH
SVRGHLNHTKYWGKWDKGRRRS*QTHPVSPSGA
QDEIRELYYFMSLSQRTFLSRKGDLSPVFIFLL
PGPPRSPTPPSLPRRCQLSSFWGRCLGREQFFKV
VKPNYHFMLSISSKQNMKWF*LESDQNENARSW
YTTDVVRTWDIPDPIWFSFTHK*HE*KKIGTIE
TGSHHVQFTASELAAVLGCVCIRFLLSYSGIRQG
VGCFS*LDKIFSKVFLRTNQKTIRVGPRI**CW
MPCRHHSVSNIGQQLLLNELFL*LESVPSEPLH
Q*LLQV*FWSVTLYIYHNVPCIYWQ*PWKIWPSL
GVSFSICQVPLCQDCRAPLSSSVTPHSCPSLGR
PWPTACRE*SRPASLSSHPHTPLLLSSDSTSLM
WEVLASFPSSIPSSIFPAVKSNPVSNLNADHLFK
STKHNPEYVEYGQHIYSLLYLTIFCFLTVPVFY
L*LLSIHDVLKSPLAVIYKRQCIQQPSAVSPDR
CRISECFHVNAALL*HVSKWT*PLTN*LPLDCNK
KCENEDLFLLIYLKRNLCASNKAFILC

Frame 2

ARTARTAPRRGLGTPGPPP*LPAR*RCPAR*RP
TPPPSWRRCTSCRRPRPISKLSTPRSL*TTSGR
TQRVGECSLSIIQPQENRCVKFKKQTRQI*TKQ
CRQPAWLSLLVQCGEGWMLQKGDVCWISLQTWWN
GTGQFLQPWNP*MVANHSCKLFMWICRASSKPF
DITQAGLIKFMG*PFL*METILPLQDMNPLECV
DRSSHGTSPC*CLPGK*LQLCAVAIQ*LLSQQSK
HHSVHSTWEPSSRRLAFLPGSSIFCQDMGQRLG
QQ*LLTLA*TRLHSQGLLRLESLSKKQLEEVI*
RE*LWNLEAKVLILFLLMLTWTMLWSRPTRVCSS
IKVSAALQALASSWRSPSMRSL*EEAWSGPRGA
*WGVPLTPPLSRVPRLIRNSTTRSWNSSRVVWL
RAPSWNVEAKDWAERGFSLSPQCFPTSLMICGLP
RRRSLALFRKF*DLRRWMKLSKEPITQTLDS*Q
LSLLMTSTRPSQCLLQCKLGLFGSIVTMP*MPR
APLGDSRCLEMGEKWENLACGSTQKLRR*Q*RSP
RRTPKKAKKEDEAQPARLSLSAFSVGPSSQEYK
VEPRSLLKD*KDNM*ARQVTAQLKQTSWVQFLG
TL*GATLIIPNIGESGIKGGGGASRHIQYLLLEH
RMK*GSCIISCLCHKELSSQGKVTFLLSSFSSF
QALLAHPPLPLFQGDVS*AHSGADVWAGNNFSR
L*SQIIISCYPFLQSKT*NGFS*SQTRMKMPGAG
TLQM**EPGIFLTQSGFLLPINNMNEKRLGQ*R
LEVIMCSSPLLSLLQFWGVCVLDSFSVILE*GK
EWVVFHS*IRSFPKFFLEPTKKQSE*AQEFDNAG
CLADIIQFLILGNNYY*MNYFCSWNLYLLNLYT
NNCCRCDFGLSHCTSIIMCPVSIGSDLGKSGQA
*GFPFPFAKFHCARTAVLH*APLSHPILAPHWAG
HGLQLAGSKAGPPPFLPIHILLFCFPVTPPV*C
GKC*LPFLLPSLLPSFQLSNPIQSLT*MQIIYL
KVPNITQSMWNMGNIYIAFCI*RSSAS*PYQFSI
YNSYLSMMF*SLHLLLFTNDSAFSSPVP*ALTD
AVFLSASM*MLPSCSMCPSGHSH*PTSYLWTAT
KNVKMKIYFF*FT*KETSVLAIKHLYCV

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