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Sequences

Sequence NM_002433

GTGGGGCTGTTTCTGCGGGCACAGCTGCAGCAATTACCGGAGTGGAGGCAGGGCCCAGGCAGCACTGCCCTCCAAGATCTTCCCTTGGGCTTTTCAGCAG TAAGGGGACATGCACCCCAAGGGCCTCCACTTGGCCTGACCTTGCTGCGGGGGCTCTCTGTCCCCAGGAACAGTAGAGATGGCAAGCTTATCAAGACCCT CTCTGCCCAGCTGCCTCTGCTCCTTCCTCCTCCTCCTCCTCCTCCAAGTGTCTTCCAGCTATGCAGGGCAGTTCAGAGTGATAGGACCAAGACACCCTAT CCGGGCTCTGGTCGGGGATGAAGTGGAATTGCCATGTCGCATATCTCCTGGGAAGAACGCTACAGGCATGGAGGTGGGGTGGTACCGCCCCCCCTTCTCT AGGGTGGTTCATCTCTACAGAAATGGCAAGGACCAAGATGGAGACCAGGCACCTGAATATCGGGGCCGGACAGAGCTGCTGAAAGATGCTATTGGTGAGG GAAAGGTGACTCTCAGGATCCGGAATGTAAGGTTCTCAGATGAAGGAGGTTTCACCTGCTTCTTCCGAGATCATTCTTACCAAGAGGAGGCAGCAATGGA ATTGAAAGTAGAAGATCCTTTCTACTGGGTGAGCCCTGGAGTGCTGGTTCTCCTCGCGGTGCTGCCTGTGCTCCTCCTGCAGATCACTGTTGGCCTCATC TTCCTCTGCCTGCAGTACAGACTGAGAGGAAAACTTCGAGCAGAGATAGAGAATCTCCACCGGACTTTTGATCCCCACTTTCTGAGGGTGCCCTGCTGGA AGATAACCCTGTTTGTAATTGTGCCGGTTCTTGGACCCTTGGTTGCCTTGATCATCTGCTACAACTGGCTACATCGAAGACTAGCAGGGCAATTCCTTGA AGAGCTACTCTTCCACCTGGAAGCCCTCTCTGGCTAAGGACAGGCAGGTGCCCCTCTCTCCATCAGAGGACACCTGTACTGGAGAGCAACACAGGATGGT CTCTGCCATGAACTGGAGGCCAGGAATCTCCTCACTGAAAATTACAGTATGGTAACTTTGCAAATGGTGGTTGTTTCTTCCAAGACTCCAGCCCTGATTG CGCAAAACTGAAAGGCATGTGAAGGGAAGGAAGAGGAAGAGTGCAAAACATTGAAGAGAGAGCTGAGTGAGCTGAAGAGTGAGGATATGAGTAGCCCCAA CCCAAACCTGGAGATGGGGAGAAACCTACAGAATACTAGCCAGAGCTCCTCCTTGTCTTGGCAGCCTACTAGGGACCTGGGGAAGCAAAAACGAAAGCTG GGCAACATGCCTGCTTTAGAATGTTTTCCTTCTACTTACACATCTTCCACAGGTCTCAGAATCTTTCCTTCCTCTCATCCTTTTCTCCTATCTTCATATC TATCAGAGTATCCACTGTTTATTCAACAACTACTACTTGATGGTCAGACACAAACAAACAAGCTAGGTGCTAATTAATAAAGATACGAGTTTTGGCCGGG TGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGAATCACGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACC CCATCTCTACTAAAAATACAAACAATTAACTGAGCATAGTGGTGGGCACCTATAATACCAGCTACTCCGGAGGCTGAGGCAGGAGAATCGCTTGAACCCA GGAGGCAGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCTAGCCGGAGTGACAGAGTAAGACTCTGTCTCAAAAATAAATAAATAAATAAATAAAT AAATAAATAAATAAATAAATAAAAAATAATAATACAAGTTTTCATAAGCACACTTCTAA

refseq_MOG.F5 (forward primer)
refseq_MOG.R5 (reverse primer)
Single exon skipping

Frame 0

VGLFLRAQLQQLPEWRQGPGSTALQDLPLGFSA VRGHAPQGPPLGLTLLRGLSVPRNSRDGKLIKTL SAQLPLLLPPPPPPPSVFQLCRAVQSDRTKTPY PGSGRG*SGIAMSHISWEERYRHGGGVVPPPLL *GGSSLQKWQGPRWRPGT*ISGPDRAAERCYW*G KGDSQDPECKVLR*RRFHLLLPRSFLPRGGSNG IESRRSFLLGEPWSAGSPRGAACAPPADHCWPH LPLPAVQTERKTSSRDRESPPDF*SPLSEGALLE DNPVCNCAGSWTLGCLDHLLQLATSKTSRAIP* RATLPPGSPLWLRTGRCPSLHQRTPVLESNTGW SLP*TGGQESPH*KLQYGNFANGGCFFQDSSPDC AKLKGM*REGRGRVQNIEERAE*AEE*GYE*PQ PKPGDGEKPTEY*PELLLVLAAY*GPGEAKTKA GQHACFRMFSFYLHIFHRSQNLSFLSSFSPIFIS IRVSTVYSTTTT*WSDTNKQARC*LIKIRVLAG CGGSRL*SQHFGRPRRANHEVRSSRPAWPTW*N PISTKNTNN*LSIVVGTYNTSYSGG*GRRIA*TQ EAEVAVS*DRATAL*PE*QSKTLSQK*INK*IN K*INK*IKNNNTSFHKHTS

Frame 1

WGCFCGHSCSNYRSGGRAQAALPSKIFPWAFQQ *GDMHPKGLHLA*PCCGGSLSPGTVEMASLSRP SLPSCLCSFLLLLLLQVSSSYAGQFRVIGPRHPI RALVGDEVELPCRISPGKNATGMEVGWYRPPFS RVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGE GKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAME LKVEDPFYWVSPGVLVLLAVLPVLLLQITVGLI FLCLQYRLRGKLRAEIENLHRTFDPHFLRVPCW KITLFVIVPVLGPLVALIICYNWLHRRLAGQFLE ELLFHLEALSG*GQAGAPLSIRGHLYWRATQDG LCHELEARNLLTENYSMVTLQMVVVSSKTPALI AQN*KACEGKEEEECKTLKRELSELKSEDMSSPN PNLEMGRNLQNTSQSSSLSWQPTRDLGKQKRKL GNMPALECFPSTYTSSTGLRIFPSSHPFLLSSY LSEYPLFIQQLLLDGQTQTNKLGAN**RYEFWPG AVAHACNPSTLGGRGGRITRSGVQDQPGQHGET PSLLKIQTIN*A*WWAPIIPATPEAEAGESLEP RRQRLQ*AEIVPLHSSRSDRVRLCLKNK*INK*I NK*INK*KIIIQVFISTLL

Frame 2

GAVSAGTAAAITGVEAGPRQHCPPRSSLGLFSS KGTCTPRASTWPDLAAGALCPQEQ*RWQAYQDP LCPAASAPSSSSSSSKCLPAMQGSSE**DQDTL SGLWSGMKWNCHVAYLLGRTLQAWRWGGTAPPSL GWFISTEMARTKMETRHLNIGAGQSC*KMLLVR ER*LSGSGM*GSQMKEVSPASSEIILTKRRQQW N*K*KILSTG*ALECWFSSRCCLCSSCRSLLASS SSACSTD*EENFEQR*RISTGLLIPTF*GCPAG R*PCL*LCRFLDPWLP*SSATTGYIED*QGNSL KSYSSTWKPSLAKDRQVPLSPSEDTCTGEQHRMV SAMNWRPGISSLKITVW*LCKWWLFLPRLQP*L RKTERHVKGRKRKSAKH*RES*VS*RVRI*VAP TQTWRWGETYRILARAPPCLGSLLGTWGSKNESW ATCLL*NVFLLLTHLPQVSESFLPLILFSYLHI YQSIHCLFNNYYLMVRHKQTS*VLINKDTSFGR VRWLTPVIPALWEAEAGESRGQEFKTSLANMVKP HLY*KYKQLTEHSGGHL*YQLLRRLRQENRLNP GGRGCSELRSCHCTLAGVTE*DSVSKINK*INK *INK*INKK**YKFS*AHF*

Sequence NM_206809

GTGGGGCTGTTTCTGCGGGCACAGCTGCAGCAATTACCGGAGTGGAGGCAGGGCCCAGGCAGCACTGCCCTCCAAGATCTTCCCTTGGGCTTTTCAGCAG TAAGGGGACATGCACCCCAAGGGCCTCCACTTGGCCTGACCTTGCTGCGGGGGCTCTCTGTCCCCAGGAACAGTAGAGATGGCAAGCTTATCAAGACCCT CTCTGCCCAGCTGCCTCTGCTCCTTCCTCCTCCTCCTCCTCCTCCAAGTGTCTTCCAGCTATGCAGGGCAGTTCAGAGTGATAGGACCAAGACACCCTAT CCGGGCTCTGGTCGGGGATGAAGTGGAATTGCCATGTCGCATATCTCCTGGGAAGAACGCTACAGGCATGGAGGTGGGGTGGTACCGCCCCCCCTTCTCT AGGGTGGTTCATCTCTACAGAAATGGCAAGGACCAAGATGGAGACCAGGCACCTGAATATCGGGGCCGGACAGAGCTGCTGAAAGATGCTATTGGTGAGG GAAAGGTGACTCTCAGGATCCGGAATGTAAGGTTCTCAGATGAAGGAGGTTTCACCTGCTTCTTCCGAGATCATTCTTACCAAGAGGAGGCAGCAATGGA ATTGAAAGTAGAAGATCCTTTCTACTGGGTGAGCCCTGGAGTGCTGGTTCTCCTCGCGGTGCTGCCTGTGCTCCTCCTGCAGATCACTGTTGGCCTCATC TTCCTCTGCCTGCAGTACAGACTGAGAGGAAAACTTCGAGCAGAGATAGAGAATCTCCACCGGACTTTTGATCCCCACTTTCTGAGGGTGCCCTGCTGGA AGATAACCCTGTTTGTAATTGTGCCGGTTCTTGGACCCTTGGTTGCCTTGATCATCTGCTACAACTGGCTACATCGAAGACTAGCAGGGCAATTCCTTGA AGAGCTACGAAATCCCTTCTGAGTGATGTCACATCTTGGCAGGGGTGGAGGAGAGCCTGGTTGCCCAGGGATTTGTCCTTGGGGACATCTCATCCATCAA GTTGCACACTCACTGGCATCTTTGCTATGGGGACATTCCAATTTGCACTTTCAGGAACACTCTGAATTCCAAGTAGAATTGATTTCCCTTCTTCTGTCAT CTACCTTTTCTCTTCATTTTCCCATTTTTATTACCCTTCTTTCCATTTCTCTCTCCAGTCTTCCACCTGGAAGCCCTCTCTGGCTAAGGACAGGCAGGTG CCCCTCTCTCCATCAGAGGACACCTGTACTGGAGAGCAACACAGGATGGTCTCTGCCATGAACTGGAGGCCAGGAATCTCCTCACTGAAAATTACAGTAT GGTAACTTTGCAAATGGTGGTTGTTTCTTCCAAGACTCCAGCCCTGATTGCGCAAAACTGAAAGGCATGTGAAGGGAAGGAAGAGGAAGAGTGCAAAACA TTGAAGAGAGAGCTGAGTGAGCTGAAGAGTGAGGATATGAGTAGCCCCAACCCAAACCTGGAGATGGGGAGAAACCTACAGAATACTAGCCAGAGCTCCT CCTTGTCTTGGCAGCCTACTAGGGACCTGGGGAAGCAAAAACGAAAGCTGGGCAACATGCCTGCTTTAGAATGTTTTCCTTCTACTTACACATCTTCCAC AGGTCTCAGAATCTTTCCTTCCTCTCATCCTTTTCTCCTATCTTCATATCTATCAGAGTATCCACTGTTTATTCAACAACTACTACTTGATGGTCAGACA CAAACAAACAAGCTAGGTGCTAATTAATAAAGATACGAGTTTTGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGC GAATCACGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAACAATTAACTGAGCATAGTGGTGGGCACC TATAATACCAGCTACTCCGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCTAGCCGG AGTGACAGAGTAAGACTCTGTCTCAAAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAAAAATAATAATACAAGTTTTCATAAGCA CACTTCTAA

refseq_MOG.F5 (forward primer)
refseq_MOG.R5 (reverse primer)
Single exon skipping

Frame 0

VGLFLRAQLQQLPEWRQGPGSTALQDLPLGFSA VRGHAPQGPPLGLTLLRGLSVPRNSRDGKLIKTL SAQLPLLLPPPPPPPSVFQLCRAVQSDRTKTPY PGSGRG*SGIAMSHISWEERYRHGGGVVPPPLL *GGSSLQKWQGPRWRPGT*ISGPDRAAERCYW*G KGDSQDPECKVLR*RRFHLLLPRSFLPRGGSNG IESRRSFLLGEPWSAGSPRGAACAPPADHCWPH LPLPAVQTERKTSSRDRESPPDF*SPLSEGALLE DNPVCNCAGSWTLGCLDHLLQLATSKTSRAIP* RATKSLLSDVTSWQGWRRAWLPRDLSLGTSHPS SCTLTGIFAMGTFQFALSGTL*IPSRIDFPSSVI YLFSSFSHFYYPSFHFSLQSSTWKPSLAKDRQV PLSPSEDTCTGEQHRMVSAMNWRPGISSLKITV W*LCKWWLFLPRLQP*LRKTERHVKGRKRKSAKH *RES*VS*RVRI*VAPTQTWRWGETYRILARAP PCLGSLLGTWGSKNESWATCLL*NVFLLLTHLP QVSESFLPLILFSYLHIYQSIHCLFNNYYLMVRH KQTS*VLINKDTSFGRVRWLTPVIPALWEAEAG ESRGQEFKTSLANMVKPHLY*KYKQLTEHSGGH L*YQLLRRLRQENRLNPGGRGCSELRSCHCTLAG VTE*DSVSKINK*INK*INK*INKK**YKFS*A HF*

Frame 1

WGCFCGHSCSNYRSGGRAQAALPSKIFPWAFQQ *GDMHPKGLHLA*PCCGGSLSPGTVEMASLSRP SLPSCLCSFLLLLLLQVSSSYAGQFRVIGPRHPI RALVGDEVELPCRISPGKNATGMEVGWYRPPFS RVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGE GKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAME LKVEDPFYWVSPGVLVLLAVLPVLLLQITVGLI FLCLQYRLRGKLRAEIENLHRTFDPHFLRVPCW KITLFVIVPVLGPLVALIICYNWLHRRLAGQFLE ELRNPF*VMSHLGRGGGEPGCPGICPWGHLIHQ VAHSLASLLWGHSNLHFQEHSEFQVELISLLLS STFSLHFPIFITLLSISLSSLPPGSPLWLRTGRC PSLHQRTPVLESNTGWSLP*TGGQESPH*KLQY GNFANGGCFFQDSSPDCAKLKGM*REGRGRVQN IEERAE*AEE*GYE*PQPKPGDGEKPTEY*PELL LVLAAY*GPGEAKTKAGQHACFRMFSFYLHIFH RSQNLSFLSSFSPIFISIRVSTVYSTTTT*WSD TNKQARC*LIKIRVLAGCGGSRL*SQHFGRPRRA NHEVRSSRPAWPTW*NPISTKNTNN*LSIVVGT YNTSYSGG*GRRIA*TQEAEVAVS*DRATAL*P E*QSKTLSQK*INK*INK*INK*IKNNNTSFHKH TS

Frame 2

GAVSAGTAAAITGVEAGPRQHCPPRSSLGLFSS KGTCTPRASTWPDLAAGALCPQEQ*RWQAYQDP LCPAASAPSSSSSSSKCLPAMQGSSE**DQDTL SGLWSGMKWNCHVAYLLGRTLQAWRWGGTAPPSL GWFISTEMARTKMETRHLNIGAGQSC*KMLLVR ER*LSGSGM*GSQMKEVSPASSEIILTKRRQQW N*K*KILSTG*ALECWFSSRCCLCSSCRSLLASS SSACSTD*EENFEQR*RISTGLLIPTF*GCPAG R*PCL*LCRFLDPWLP*SSATTGYIED*QGNSL KSYEIPSE*CHILAGVEESLVAQGFVLGDISSIK LHTHWHLCYGDIPICTFRNTLNSK*N*FPFFCH LPFLFIFPFLLPFFPFLSPVFHLEALSG*GQAG APLSIRGHLYWRATQDGLCHELEARNLLTENYSM VTLQMVVVSSKTPALIAQN*KACEGKEEEECKT LKRELSELKSEDMSSPNPNLEMGRNLQNTSQSS SLSWQPTRDLGKQKRKLGNMPALECFPSTYTSST GLRIFPSSHPFLLSSYLSEYPLFIQQLLLDGQT QTNKLGAN**RYEFWPGAVAHACNPSTLGGRGG RITRSGVQDQPGQHGETPSLLKIQTIN*A*WWAP IIPATPEAEAGESLEPRRQRLQ*AEIVPLHSSR SDRVRLCLKNK*INK*INK*INK*KIIIQVFIS TLL

Sequence NM_206814

GTGGGGCTGTTTCTGCGGGCACAGCTGCAGCAATTACCGGAGTGGAGGCAGGGCCCAGGCAGCACTGCCCTCCAAGATCTTCCCTTGGGCTTTTCAGCAG TAAGGGGACATGCACCCCAAGGGCCTCCACTTGGCCTGACCTTGCTGCGGGGGCTCTCTGTCCCCAGGAACAGTAGAGATGGCAAGCTTATCAAGACCCT CTCTGCCCAGCTGCCTCTGCTCCTTCCTCCTCCTCCTCCTCCTCCAAGTGTCTTCCAGCTATGCAGGGCAGTTCAGAGTGATAGGACCAAGACACCCTAT CCGGGCTCTGGTCGGGGATGAAGTGGAATTGCCATGTCGCATATCTCCTGGGAAGAACGCTACAGGCATGGAGGTGGGGTGGTACCGCCCCCCCTTCTCT AGGGTGGTTCATCTCTACAGAAATGGCAAGGACCAAGATGGAGACCAGGCACCTGAATATCGGGGCCGGACAGAGCTGCTGAAAGATGCTATTGGTGAGG GAAAGGTGACTCTCAGGATCCGGAATGTAAGGTTCTCAGATGAAGGAGGTTTCACCTGCTTCTTCCGAGATCATTCTTACCAAGAGGAGGCAGCAATGGA ATTGAAAGTAGAAGTGTCTCACTCTGTCACCCAGGATTGGTTGCAGTGGCACGATCATGGCTCATTGCAGCCTCCACCTCCCAGGCTCAAGTGATCCTCC TGACTCAGCCTCTTGAATAGCTGAGACCACAGGCTTGTGTCACCATGCCCAGATCCTTTCTACTGGGTGAGCCCTGGAGTGCTGGTTCTCCTCGCGGTGC TGCCTGTGCTCCTCCTGCAGATCACTGTTGGCCTCATCTTCCTCTGCCTGCAGTACAGACTGAGAGGAAAACTTCGAGCAGAGATAGAGAATCTCCACCG GACTTTTGATCCCCACTTTCTGAGGGTGCCCTGCTGGAAGATAACCCTGTTTGTAATTGTGCCGGTTCTTGGACCCTTGGTTGCCTTGATCATCTGCTAC AACTGGCTACATCGAAGACTAGCAGGGCAATTCCTTGAAGAGCTACGAAATCCCTTCTGAGTGATGTCACATCTTGGCAGGGGTGGAGGAGAGCCTGGTT GCCCAGGGATTTGTCCTTGGGGACATCTCATCCATCAAGTTGCACACTCACTGGCATCTTTGCTATGGGGACATTCCAATTTGCACTTTCAGGAACACTC TGAATTCCAAGTAGAATTGATTTCCCTTCTTCTGTCATCTACCTTTTCTCTTCATTTTCCCATTTTTATTACCCTTCTTTCCATTTCTCTCTCCAGTCTT CCACCTGGAAGCCCTCTCTGGCTAAGGACAGGCAGGTGCCCCTCTCTCCATCAGAGGACACCTGTACTGGAGAGCAACACAGGATGGTCTCTGCCATGAA CTGGAGGCCAGGAATCTCCTCACTGAAAATTACAGTATGGTAACTTTGCAAATGGTGGTTGTTTCTTCCAAGACTCCAGCCCTGATTGCGCAAAACTGAA AGGCATGTGAAGGGAAGGAAGAGGAAGAGTGCAAAACATTGAAGAGAGAGCTGAGTGAGCTGAAGAGTGAGGATATGAGTAGCCCCAACCCAAACCTGGA GATGGGGAGAAACCTACAGAATACTAGCCAGAGCTCCTCCTTGTCTTGGCAGCCTACTAGGGACCTGGGGAAGCAAAAACGAAAGCTGGGCAACATGCCT GCTTTAGAATGTTTTCCTTCTACTTACACATCTTCCACAGGTCTCAGAATCTTTCCTTCCTCTCATCCTTTTCTCCTATCTTCATATCTATCAGAGTATC CACTGTTTATTCAACAACTACTACTTGATGGTCAGACACAAACAAACAAGCTAGGTGCTAATTAATAAAGATACGAGTTTTGGCCGGGTGCGGTGGCTCA CGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGAATCACGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTA AAAATACAAACAATTAACTGAGCATAGTGGTGGGCACCTATAATACCAGCTACTCCGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAGGT TGCAGTGAGCTGAGATCGTGCCACTGCACTCTAGCCGGAGTGACAGAGTAAGACTCTGTCTCAAAAATAAATAAATAAATAAATAAATAAATAAATAAAT AAATAAATAAAAAATAATAATACAAGTTTTCATAAGCACACTTCTAA

refseq_MOG.F5 (forward primer)
refseq_MOG.R5 (reverse primer)
Single exon skipping

Frame 0

VGLFLRAQLQQLPEWRQGPGSTALQDLPLGFSA VRGHAPQGPPLGLTLLRGLSVPRNSRDGKLIKTL SAQLPLLLPPPPPPPSVFQLCRAVQSDRTKTPY PGSGRG*SGIAMSHISWEERYRHGGGVVPPPLL *GGSSLQKWQGPRWRPGT*ISGPDRAAERCYW*G KGDSQDPECKVLR*RRFHLLLPRSFLPRGGSNG IESRSVSLCHPGLVAVARSWLIAASTSQAQVIL LTQPLE*LRPQACVTMPRSFLLGEPWSAGSPRGA ACAPPADHCWPHLPLPAVQTERKTSSRDRESPP DF*SPLSEGALLEDNPVCNCAGSWTLGCLDHLL QLATSKTSRAIP*RATKSLLSDVTSWQGWRRAWL PRDLSLGTSHPSSCTLTGIFAMGTFQFALSGTL *IPSRIDFPSSVIYLFSSFSHFYYPSFHFSLQS STWKPSLAKDRQVPLSPSEDTCTGEQHRMVSAMN WRPGISSLKITVW*LCKWWLFLPRLQP*LRKTE RHVKGRKRKSAKH*RES*VS*RVRI*VAPTQTW RWGETYRILARAPPCLGSLLGTWGSKNESWATCL L*NVFLLLTHLPQVSESFLPLILFSYLHIYQSI HCLFNNYYLMVRHKQTS*VLINKDTSFGRVRWL TPVIPALWEAEAGESRGQEFKTSLANMVKPHLY* KYKQLTEHSGGHL*YQLLRRLRQENRLNPGGRG CSELRSCHCTLAGVTE*DSVSKINK*INK*INK *INKK**YKFS*AHF*

Frame 1

WGCFCGHSCSNYRSGGRAQAALPSKIFPWAFQQ *GDMHPKGLHLA*PCCGGSLSPGTVEMASLSRP SLPSCLCSFLLLLLLQVSSSYAGQFRVIGPRHPI RALVGDEVELPCRISPGKNATGMEVGWYRPPFS RVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGE GKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAME LKVEVSHSVTQDWLQWHDHGSLQPPPPRLK*SS *LSLLNS*DHRLVSPCPDPFYWVSPGVLVLLAV LPVLLLQITVGLIFLCLQYRLRGKLRAEIENLHR TFDPHFLRVPCWKITLFVIVPVLGPLVALIICY NWLHRRLAGQFLEELRNPF*VMSHLGRGGGEPG CPGICPWGHLIHQVAHSLASLLWGHSNLHFQEHS EFQVELISLLLSSTFSLHFPIFITLLSISLSSL PPGSPLWLRTGRCPSLHQRTPVLESNTGWSLP* TGGQESPH*KLQYGNFANGGCFFQDSSPDCAKLK GM*REGRGRVQNIEERAE*AEE*GYE*PQPKPG DGEKPTEY*PELLLVLAAY*GPGEAKTKAGQHA CFRMFSFYLHIFHRSQNLSFLSSFSPIFISIRVS TVYSTTTT*WSDTNKQARC*LIKIRVLAGCGGS RL*SQHFGRPRRANHEVRSSRPAWPTW*NPIST KNTNN*LSIVVGTYNTSYSGG*GRRIA*TQEAEV AVS*DRATAL*PE*QSKTLSQK*INK*INK*IN K*IKNNNTSFHKHTS

Frame 2

GAVSAGTAAAITGVEAGPRQHCPPRSSLGLFSS KGTCTPRASTWPDLAAGALCPQEQ*RWQAYQDP LCPAASAPSSSSSSSKCLPAMQGSSE**DQDTL SGLWSGMKWNCHVAYLLGRTLQAWRWGGTAPPSL GWFISTEMARTKMETRHLNIGAGQSC*KMLLVR ER*LSGSGM*GSQMKEVSPASSEIILTKRRQQW N*K*KCLTLSPRIGCSGTIMAHCSLHLPGSSDPP DSAS*IAETTGLCHHAQILSTG*ALECWFSSRC CLCSSCRSLLASSSSACSTD*EENFEQR*RIST GLLIPTF*GCPAGR*PCL*LCRFLDPWLP*SSAT TGYIED*QGNSLKSYEIPSE*CHILAGVEESLV AQGFVLGDISSIKLHTHWHLCYGDIPICTFRNT LNSK*N*FPFFCHLPFLFIFPFLLPFFPFLSPVF HLEALSG*GQAGAPLSIRGHLYWRATQDGLCHE LEARNLLTENYSMVTLQMVVVSSKTPALIAQN* KACEGKEEEECKTLKRELSELKSEDMSSPNPNLE MGRNLQNTSQSSSLSWQPTRDLGKQKRKLGNMP ALECFPSTYTSSTGLRIFPSSHPFLLSSYLSEY PLFIQQLLLDGQTQTNKLGAN**RYEFWPGAVAH ACNPSTLGGRGGRITRSGVQDQPGQHGETPSLL KIQTIN*A*WWAPIIPATPEAEAGESLEPRRQR LQ*AEIVPLHSSRSDRVRLCLKNK*INK*INK*I NK*KIIIQVFISTLL

Sequence NM_206813

GTGGGGCTGTTTCTGCGGGCACAGCTGCAGCAATTACCGGAGTGGAGGCAGGGCCCAGGCAGCACTGCCCTCCAAGATCTTCCCTTGGGCTTTTCAGCAG TAAGGGGACATGCACCCCAAGGGCCTCCACTTGGCCTGACCTTGCTGCGGGGGCTCTCTGTCCCCAGGAACAGTAGAGATGGCAAGCTTATCAAGACCCT CTCTGCCCAGCTGCCTCTGCTCCTTCCTCCTCCTCCTCCTCCTCCAAGTGTCTTCCAGCTATGCAGGGCAGTTCAGAGTGATAGGACCAAGACACCCTAT CCGGGCTCTGGTCGGGGATGAAGTGGAATTGCCATGTCGCATATCTCCTGGGAAGAACGCTACAGGCATGGAGGTGGGGTGGTACCGCCCCCCCTTCTCT AGGGTGGTTCATCTCTACAGAAATGGCAAGGACCAAGATGGAGACCAGGCACCTGAATATCGGGGCCGGACAGAGCTGCTGAAAGATGCTATTGGTGAGG GAAAGGTGACTCTCAGGATCCGGAATGTAAGGTTCTCAGATGAAGGAGGTTTCACCTGCTTCTTCCGAGATCATTCTTACCAAGAGGAGGCAGCAATGGA ATTGAAAGTAGAAGTGTCTCACTCTGTCACCCAGGATTGGTTGCAGTGGCACGATCATGGCTCATTGCAGCCTCCACCTCCCAGGCTCAAGTGATCCTCC TGACTCAGCCTCTTGAATAGCTGAGACCACAGGCTTGTGTCACCATGCCCAGATCCTTTCTACTGGGTGAGCCCTGGAGTGCTGGTTCTCCTCGCGGTGC TGCCTGTGCTCCTCCTGCAGATCACTGTTGGCCTCATCTTCCTCTGCCTGCAGTACAGACTGAGAGGAAAACTTCGAGCAGAGATAGAGAATCTCCACCG GACTTTTGATCCCCACTTTCTGAGGGTGCCCTGCTGGAAGATAACCCTGTTTGTAATTGTGCCGGTTCTTGGACCCTTGGTTGCCTTGATCATCTGCTAC AACTGGCTACATCGAAGACTAGCAGGGCAATTCCTTGAAGAGCTACTCTTCCACCTGGAAGCCCTCTCTGGCTAAGGACAGGCAGGTGCCCCTCTCTCCA TCAGAGGACACCTGTACTGGAGAGCAACACAGGATGGTCTCTGCCATGAACTGGAGGCCAGGAATCTCCTCACTGAAAATTACAGTATGGTAACTTTGCA AATGGTGGTTGTTTCTTCCAAGACTCCAGCCCTGATTGCGCAAAACTGAAAGGCATGTGAAGGGAAGGAAGAGGAAGAGTGCAAAACATTGAAGAGAGAG CTGAGTGAGCTGAAGAGTGAGGATATGAGTAGCCCCAACCCAAACCTGGAGATGGGGAGAAACCTACAGAATACTAGCCAGAGCTCCTCCTTGTCTTGGC AGCCTACTAGGGACCTGGGGAAGCAAAAACGAAAGCTGGGCAACATGCCTGCTTTAGAATGTTTTCCTTCTACTTACACATCTTCCACAGGTCTCAGAAT CTTTCCTTCCTCTCATCCTTTTCTCCTATCTTCATATCTATCAGAGTATCCACTGTTTATTCAACAACTACTACTTGATGGTCAGACACAAACAAACAAG CTAGGTGCTAATTAATAAAGATACGAGTTTTGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGAATCACGAGGT CAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAACAATTAACTGAGCATAGTGGTGGGCACCTATAATACCAGC TACTCCGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCTAGCCGGAGTGACAGAGTA AGACTCTGTCTCAAAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAAAAATAATAATACAAGTTTTCATAAGCACACTTCTAA

refseq_MOG.F5 (forward primer)
refseq_MOG.R5 (reverse primer)
Single exon skipping

Frame 0

VGLFLRAQLQQLPEWRQGPGSTALQDLPLGFSA VRGHAPQGPPLGLTLLRGLSVPRNSRDGKLIKTL SAQLPLLLPPPPPPPSVFQLCRAVQSDRTKTPY PGSGRG*SGIAMSHISWEERYRHGGGVVPPPLL *GGSSLQKWQGPRWRPGT*ISGPDRAAERCYW*G KGDSQDPECKVLR*RRFHLLLPRSFLPRGGSNG IESRSVSLCHPGLVAVARSWLIAASTSQAQVIL LTQPLE*LRPQACVTMPRSFLLGEPWSAGSPRGA ACAPPADHCWPHLPLPAVQTERKTSSRDRESPP DF*SPLSEGALLEDNPVCNCAGSWTLGCLDHLL QLATSKTSRAIP*RATLPPGSPLWLRTGRCPSLH QRTPVLESNTGWSLP*TGGQESPH*KLQYGNFA NGGCFFQDSSPDCAKLKGM*REGRGRVQNIEER AE*AEE*GYE*PQPKPGDGEKPTEY*PELLLVLA AY*GPGEAKTKAGQHACFRMFSFYLHIFHRSQN LSFLSSFSPIFISIRVSTVYSTTTT*WSDTNKQ ARC*LIKIRVLAGCGGSRL*SQHFGRPRRANHEV RSSRPAWPTW*NPISTKNTNN*LSIVVGTYNTS YSGG*GRRIA*TQEAEVAVS*DRATAL*PE*QS KTLSQK*INK*INK*INK*IKNNNTSFHKHTS

Frame 1

WGCFCGHSCSNYRSGGRAQAALPSKIFPWAFQQ *GDMHPKGLHLA*PCCGGSLSPGTVEMASLSRP SLPSCLCSFLLLLLLQVSSSYAGQFRVIGPRHPI RALVGDEVELPCRISPGKNATGMEVGWYRPPFS RVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGE GKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAME LKVEVSHSVTQDWLQWHDHGSLQPPPPRLK*SS *LSLLNS*DHRLVSPCPDPFYWVSPGVLVLLAV LPVLLLQITVGLIFLCLQYRLRGKLRAEIENLHR TFDPHFLRVPCWKITLFVIVPVLGPLVALIICY NWLHRRLAGQFLEELLFHLEALSG*GQAGAPLS IRGHLYWRATQDGLCHELEARNLLTENYSMVTLQ MVVVSSKTPALIAQN*KACEGKEEEECKTLKRE LSELKSEDMSSPNPNLEMGRNLQNTSQSSSLSW QPTRDLGKQKRKLGNMPALECFPSTYTSSTGLRI FPSSHPFLLSSYLSEYPLFIQQLLLDGQTQTNK LGAN**RYEFWPGAVAHACNPSTLGGRGGRITR SGVQDQPGQHGETPSLLKIQTIN*A*WWAPIIPA TPEAEAGESLEPRRQRLQ*AEIVPLHSSRSDRV RLCLKNK*INK*INK*INK*KIIIQVFISTLL

Frame 2

GAVSAGTAAAITGVEAGPRQHCPPRSSLGLFSS KGTCTPRASTWPDLAAGALCPQEQ*RWQAYQDP LCPAASAPSSSSSSSKCLPAMQGSSE**DQDTL SGLWSGMKWNCHVAYLLGRTLQAWRWGGTAPPSL GWFISTEMARTKMETRHLNIGAGQSC*KMLLVR ER*LSGSGM*GSQMKEVSPASSEIILTKRRQQW N*K*KCLTLSPRIGCSGTIMAHCSLHLPGSSDPP DSAS*IAETTGLCHHAQILSTG*ALECWFSSRC CLCSSCRSLLASSSSACSTD*EENFEQR*RIST GLLIPTF*GCPAGR*PCL*LCRFLDPWLP*SSAT TGYIED*QGNSLKSYSSTWKPSLAKDRQVPLSP SEDTCTGEQHRMVSAMNWRPGISSLKITVW*LC KWWLFLPRLQP*LRKTERHVKGRKRKSAKH*RES *VS*RVRI*VAPTQTWRWGETYRILARAPPCLG SLLGTWGSKNESWATCLL*NVFLLLTHLPQVSE SFLPLILFSYLHIYQSIHCLFNNYYLMVRHKQTS *VLINKDTSFGRVRWLTPVIPALWEAEAGESRG QEFKTSLANMVKPHLY*KYKQLTEHSGGHL*YQ LLRRLRQENRLNPGGRGCSELRSCHCTLAGVTE* DSVSKINK*INK*INK*INKK**YKFS*AHF*