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Sequences

Sequence NM_170708

ACTCAGTGTTCGCGGGAGCGCCGCACCTACACCAGCCAACCCAGATCCCGAGGTCCGACAGCGCCCGGCCCAGATCCCCACGCCTGCCAGGAGCAAGCCG
AGAGCCAGCCGGCCGGCGCACTCCGACTCCGAGCAGTCTCTGTCCTTCGACCCGAGCCCCGCGCCCTTTCCGGGACCCCTGCCCCGCGGGCAGCGCTGCC
AACCTGCCGGCCATGGAGACCCCGTCCCAGCGGCGCGCCACCCGCAGCGGGGCGCAGGCCAGCTCCACTCCGCTGTCGCCCACCCGCATCACCCGGCTGC
AGGAGAAGGAGGACCTGCAGGAGCTCAATGATCGCTTGGCGGTCTACATCGACCGTGTGCGCTCGCTGGAAACGGAGAACGCAGGGCTGCGCCTTCGCAT
CACCGAGTCTGAAGAGGTGGTCAGCCGCGAGGTGTCCGGCATCAAGGCCGCCTACGAGGCCGAGCTCGGGGATGCCCGCAAGACCCTTGACTCAGTAGCC
AAGGAGCGCGCCCGCCTGCAGCTGGAGCTGAGCAAAGTGCGTGAGGAGTTTAAGGAGCTGAAAGCGCGCAATACCAAGAAGGAGGGTGACCTGATAGCTG
CTCAGGCTCGGCTGAAGGACCTGGAGGCTCTGCTGAACTCCAAGGAGGCCGCACTGAGCACTGCTCTCAGTGAGAAGCGCACGCTGGAGGGCGAGCTGCA
TGATCTGCGGGGCCAGGTGGCCAAGCTTGAGGCAGCCCTAGGTGAGGCCAAGAAGCAACTTCAGGATGAGATGCTGCGGCGGGTGGATGCTGAGAACAGG
CTGCAGACCATGAAGGAGGAACTGGACTTCCAGAAGAACATCTACAGTGAGGAGCTGCGTGAGACCAAGCGCCGTCATGAGACCCGACTGGTGGAGATTG
ACAATGGGAAGCAGCGTGAGTTTGAGAGCCGGCTGGCGGATGCGCTGCAGGAACTGCGGGCCCAGCATGAGGACCAGGTGGAGCAGTATAAGAAGGAGCT
GGAGAAGACTTATTCTGCCAAGCTGGACAATGCCAGGCAGTCTGCTGAGAGGAACAGCAACCTGGTGGGGGCTGCCCACGAGGAGCTGCAGCAGTCGCGC
ATCCGCATCGACAGCCTCTCTGCCCAGCTCAGCCAGCTCCAGAAGCAGCTGGCAGCCAAGGAGGCGAAGCTTCGAGACCTGGAGGACTCACTGGCCCGTG
AGCGGGACACCAGCCGGCGGCTGCTGGCGGAAAAGGAGCGGGAGATGGCCGAGATGCGGGCAAGGATGCAGCAGCAGCTGGACGAGTACCAGGAGCTTCT
GGACATCAAGCTGGCCCTGGACATGGAGATCCACGCCTACCGCAAGCTCTTGGAGGGCGAGGAGGAGAGGCTACGCCTGTCCCCCAGCCCTACCTCGCAG
CGCAGCCGTGGCCGTGCTTCCTCTCACTCATCCCAGACACAGGGTGGGGGCAGCGTCACCAAAAAGCGCAAACTGGAGTCCACTGAGAGCCGCAGCAGCT
TCTCACAGCACGCACGCACTAGCGGGCGCGTGGCCGTGGAGGAGGTGGATGAGGAGGGCAAGTTTGTCCGGCTGCGCAACAAGTCCAATGAGGACCAGTC
CATGGGCAATTGGCAGATCAAGCGCCAGAATGGAGATGATCCCTTGCTGACTTACCGGTTCCCACCAAAGTTCACCCTGAAGGCTGGGCAGGTGGTGACG
ATCTGGGCTGCAGGAGCTGGGGCCACCCACAGCCCCCCTACCGACCTGGTGTGGAAGGCACAGAACACCTGGGGCTGCGGGAACAGCCTGCGTACGGCTC
TCATCAACTCCACTGGGGAAGGCTCCCACTGCAGCAGCTCGGGGGACCCCGCTGAGTACAACCTGCGCTCGCGCACCGTGCTGTGCGGGACCTGCGGGCA
GCCTGCCGACAAGGCATCTGCCAGCGGCTCAGGAGCCCAGGTGGGCGGACCCATCTCCTCTGGCTCTTCTGCCTCCAGTGTCACGGTCACTCGCAGCTAC
CGCAGTGTGGGGGGCAGTGGGGGTGGCAGCTTCGGGGACAATCTGGTCACCCGCTCCTACCTCCTGGGCAACTCCAGCCCCCGAACCCAGAGCCCCCAGA
ACTGCAGCATCATGTAATCTGGGACCTGCCAGGCAGGGGTGGGGGTGGAGGCTTCCTGCGTCCTCCTCACCTCATGCCCACCCCCTGCCCTGCACGTCAT
GGGAGGGGGCTTGAAGCCAAAGAAAAATAACCCTTTGGTTTTTTTCTTCTGTATTTTTTTTTCTAAGAGAAGTTATTTTCTACAGTGGTTTTATACTGAA
GGAAAAACACAAGCAAAAAAAAAAAAAAGCATCTATCTCATCTATCTCAATCCTAATTTCTCCTCCCTTCCTTTTCCCTGCTTCCAGGAAACTCCACATC
TGCCTTAAAACCAAAGAGGGCTTCCTCTAGAAGCCAAGGGAAAGGGGTGCTTTTATAGAGGCTAGCTTCTGCTTTTCTGCCCTGGCTGCTGCCCCCACCC
CGGGGACCCTGTGACATGGTGCCTGAGAGGCAGGCATAGAGGCTTCTCCGCCAGCCTCCTCTGGACGGCAGGCTCACTGCCAGGCCAGCCTCCGAGAGGG
AGAGAGAGAGAGAGAGGACAGCTTGAGCCGGGCCCCTGGGCTTGGCCTGCTGTGATTCCACTACACCTGGCTGAGGTTCCTCTGCCTGCCCCGCCCCCAG
TCCCCACCCCTGCCCCCAGCCCCGGGGTGAGTCCATTCTCCCAGGTACCAGCTGCGCTTGCTTTTCTGTATTTTATTTAGACAAGAGATGGGAATGAGGT
GGGAGGTGGAAGAAGGGAGAAGAAAGGTGAGTTTGAGCTGCCTTCCCTAGCTTTAGACCCTGGGTGGGCTCTGTGCAGTCACTGGAGGTTGAAGCCAAGT
GGGGTGCTGGGAGGAGGGAGAGGGAGGTCACTGGAAAGGGGAGAGCCTGCTGGCACCCACCGTGGAGGAGGAAGGCAAGAGGGGGTGGAGGGGTGTGGCA
GTGGTTTTGGCAAACGCTAAAGAGCCCTTGCCTCCCCATTTCCCATCTGCACCCCTTCTCTCCTCCCCAAATCAATACACTAGTTGTTTCT
  • refseq_LMNA.F1 (forward primer)
  • refseq_LMNA.R1 (reverse primer)
  • Single exon skipping

Frame 0

TQCSRERRTYTSQPRSRGPTAPGPDPHACQEQA
ESQPAGALRLRAVSVLRPEPRALSGTPAPRAALP
TCRPWRPRPSGAPPAAGRRPAPLRCRPPASPGC
RRRRTCRSSMIAWRSTSTVCARWKRRTQGCAFA
SPSLKRWSAARCPASRPPTRPSSGMPARPLTQ*P
RSAPACSWS*AKCVRSLRS*KRAIPRRRVT**L
LRLG*RTWRLC*TPRRPH*ALLSVRSARWRASC
MICGARWPSLRQP*VRPRSNFRMRCCGGWMLRTG
CRP*RRNWTSRRTSTVRSCVRPSAVMRPDWWRL
TMGSSVSLRAGWRMRCRNCGPSMRTRWSSIRRS
WRRLILPSWTMPGSLLRGTATWWGLPTRSCSSRA
SASTASLPSSASSRSSWQPRRRSFETWRTHWPV
SGTPAGGCWRKRSGRWPRCGQGCSSSWTSTRSF
WTSSWPWTWRSTPTASSWRARRRGYACPPALPRS
AAVAVLPLTHPRHRVGAASPKSANWSPLRAAAA
SHSTHALAGAWPWRRWMRRASLSGCATSPMRTS
PWAIGRSSARMEMIPC*LTGSHQSSP*RLGRW*R
SGLQELGPPTAPLPTWCGRHRTPGAAGTACVRL
SSTPLGKAPTAAARGTPLSTTCARAPCCAGPAG
SLPTRHLPAAQEPRWADPSPLALLPPVSRSLAAT
AVWGAVGVAASGTIWSPAPTSWATPAPEPRAPR
TAASCNLGPARQGWGWRLPASSSPHAHPLPCTS
WEGA*SQRKITLWFFSSVFFFLREVIFYSGFILK
EKHKQKKKKASISSISILISPPFLFPASRKLHI
CLKTKEGFL*KPRERGAFIEASFCFSALAAAPT
PGTL*HGA*EAGIEASPPASSGRQAHCQASLREG
EREREDSLSRAPGLGLL*FHYTWLRFLCLPRPQ
SPPLPPAPG*VHSPRYQLRLLFCILFRQEMGMR
WEVEEGRRKVSLSCLP*L*TLGGLCAVTGG*SQV
GCWEEGEGGHWKGESLLAPTVEEEGKRGWRGVA
VVLANAKEPLPPHFPSAPLLSSPNQYTSCF

Frame 1

LSVRGSAAPTPANPDPEVRQRPAQIPTPARSKP
RASRPAHSDSEQSLSFDPSPAPFPGPLPRGQRC
QPAGHGDPVPAARHPQRGAGQLHSAVAHPHHPAA
GEGGPAGAQ*SLGGLHRPCALAGNGERRAAPSH
HRV*RGGQPRGVRHQGRLRGRARGCPQDP*LSS
QGARPPAAGAEQSA*GV*GAESAQYQEGG*PDSC
SGSAEGPGGSAELQGGRTEHCSQ*EAHAGGRAA
*SAGPGGQA*GSPR*GQEATSG*DAAAGGC*EQ
AADHEGGTGLPEEHLQ*GAA*DQAPS*DPTGGD*
QWEAA*V*EPAGGCAAGTAGPA*GPGGAV*EGA
GEDLFCQAGQCQAVC*EEQQPGGGCPRGAAAVA
HPHRQPLCPAQPAPEAAGSQGGEASRPGGLTGP*
AGHQPAAAGGKGAGDGRDAGKDAAAAGRVPGAS
GHQAGPGHGDPRLPQALGGRGGEATPVPQPYLA
AQPWPCFLSLIPDTGWGQRHQKAQTGVH*EPQQL
LTARTH*RARGRGGGG*GGQVCPAAQQVQ*GPV
HGQLADQAPEWR*SLADLPVPTKVHPEGWAGGD
DLGCRSWGHPQPPYRPGVEGTEHLGLREQPAYGS
HQLHWGRLPLQQLGGPR*VQPALAHRAVRDLRA
ACRQGICQRLRSPGGRTHLLWLFCLQCHGHSQL
PQCGGQWGWQLRGQSGHPLLPPGQLQPPNPEPPE
LQHHVIWDLPGRGGGGGFLRPPHLMPTPCPARH
GRGLEAKEK*PFGFFLLYFFF*EKLFSTVVLY*
RKNTSKKKKKHLSHLSQS*FLLPSFSLLPGNSTS
ALKPKRASSRSQGKGVLL*RLASAFLPWLLPPP
RGPCDMVPERQA*RLLRQPPLDGRLTARPASER
ERERERTA*AGPLGLACCDSTTPG*GSSACPAPS
PHPCPQPRGESILPGTSCACFSVFYLDKRWE*G
GRWKKGEER*V*AAFPSFRPWVGSVQSLEVEAK
WGAGRREREVTGKGRACWHPPWRRKARGGGGVWQ
WFWQTLKSPCLPISHLHPFSPPQINTLVVS

Frame 2

SVFAGAPHLHQPTQIPRSDSARPRSPRLPGASR
EPAGRRTPTPSSLCPSTRAPRPFRDPCPAGSAA
NLPAMETPSQRRATRSGAQASSTPLSPTRITRL
QEKEDLQELNDRLAVYIDRVRSLETENAGLRLRI
TESEEVVSREVSGIKAAYEAELGDARKTLDSVA
KERARLQLELSKVREEFKELKARNTKKEGDLIA
AQARLKDLEALLNSKEAALSTALSEKRTLEGELH
DLRGQVAKLEAALGEAKKQLQDEMLRRVDAENR
LQTMKEELDFQKNIYSEELRETKRRHETRLVEI
DNGKQREFESRLADALQELRAQHEDQVEQYKKEL
EKTYSAKLDNARQSAERNSNLVGAAHEELQQSR
IRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLAR
ERDTSRRLLAEKEREMAEMRARMQQQLDEYQELL
DIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQ
RSRGRASSHSSQTQGGGSVTKKRKLESTESRSS
FSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQS
MGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVT
IWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTA
LINSTGEGSHCSSSGDPAEYNLRSRTVLCGTCGQ
PADKASASGSGAQVGGPISSGSSASSVTVTRSY
RSVGGSGGGSFGDNLVTRSYLLGNSSPRTQSPQ
NCSIM*SGTCQAGVGVEASCVLLTSCPPPALHVM
GGGLKPKKNNPLVFFFCIFFSKRSYFLQWFYTE
GKTQAKKKKSIYLIYLNPNFSSLPFPCFQETPH
LP*NQRGLPLEAKGKGCFYRG*LLLFCPGCCPHP
GDPVTWCLRGRHRGFSASLLWTAGSLPGQPPRG
RERERGQLEPGPWAWPAVIPLHLAEVPLPAPPP
VPTPAPSPGVSPFSQVPAALAFLYFI*TRDGNEV
GGGRREKKGEFELPSLALDPGWALCSHWRLKPS
GVLGGGRGRSLERGEPAGTHRGGGRQEGVEGCG
SGFGKR*RALASPFPICTPSLLPKSIH*LF

Sequence NM_170707

ACTCAGTGTTCGCGGGAGCGCCGCACCTACACCAGCCAACCCAGATCCCGAGGTCCGACAGCGCCCGGCCCAGATCCCCACGCCTGCCAGGAGCAAGCCG
AGAGCCAGCCGGCCGGCGCACTCCGACTCCGAGCAGTCTCTGTCCTTCGACCCGAGCCCCGCGCCCTTTCCGGGACCCCTGCCCCGCGGGCAGCGCTGCC
AACCTGCCGGCCATGGAGACCCCGTCCCAGCGGCGCGCCACCCGCAGCGGGGCGCAGGCCAGCTCCACTCCGCTGTCGCCCACCCGCATCACCCGGCTGC
AGGAGAAGGAGGACCTGCAGGAGCTCAATGATCGCTTGGCGGTCTACATCGACCGTGTGCGCTCGCTGGAAACGGAGAACGCAGGGCTGCGCCTTCGCAT
CACCGAGTCTGAAGAGGTGGTCAGCCGCGAGGTGTCCGGCATCAAGGCCGCCTACGAGGCCGAGCTCGGGGATGCCCGCAAGACCCTTGACTCAGTAGCC
AAGGAGCGCGCCCGCCTGCAGCTGGAGCTGAGCAAAGTGCGTGAGGAGTTTAAGGAGCTGAAAGCGCGCAATACCAAGAAGGAGGGTGACCTGATAGCTG
CTCAGGCTCGGCTGAAGGACCTGGAGGCTCTGCTGAACTCCAAGGAGGCCGCACTGAGCACTGCTCTCAGTGAGAAGCGCACGCTGGAGGGCGAGCTGCA
TGATCTGCGGGGCCAGGTGGCCAAGCTTGAGGCAGCCCTAGGTGAGGCCAAGAAGCAACTTCAGGATGAGATGCTGCGGCGGGTGGATGCTGAGAACAGG
CTGCAGACCATGAAGGAGGAACTGGACTTCCAGAAGAACATCTACAGTGAGGAGCTGCGTGAGACCAAGCGCCGTCATGAGACCCGACTGGTGGAGATTG
ACAATGGGAAGCAGCGTGAGTTTGAGAGCCGGCTGGCGGATGCGCTGCAGGAACTGCGGGCCCAGCATGAGGACCAGGTGGAGCAGTATAAGAAGGAGCT
GGAGAAGACTTATTCTGCCAAGCTGGACAATGCCAGGCAGTCTGCTGAGAGGAACAGCAACCTGGTGGGGGCTGCCCACGAGGAGCTGCAGCAGTCGCGC
ATCCGCATCGACAGCCTCTCTGCCCAGCTCAGCCAGCTCCAGAAGCAGCTGGCAGCCAAGGAGGCGAAGCTTCGAGACCTGGAGGACTCACTGGCCCGTG
AGCGGGACACCAGCCGGCGGCTGCTGGCGGAAAAGGAGCGGGAGATGGCCGAGATGCGGGCAAGGATGCAGCAGCAGCTGGACGAGTACCAGGAGCTTCT
GGACATCAAGCTGGCCCTGGACATGGAGATCCACGCCTACCGCAAGCTCTTGGAGGGCGAGGAGGAGAGGCTACGCCTGTCCCCCAGCCCTACCTCGCAG
CGCAGCCGTGGCCGTGCTTCCTCTCACTCATCCCAGACACAGGGTGGGGGCAGCGTCACCAAAAAGCGCAAACTGGAGTCCACTGAGAGCCGCAGCAGCT
TCTCACAGCACGCACGCACTAGCGGGCGCGTGGCCGTGGAGGAGGTGGATGAGGAGGGCAAGTTTGTCCGGCTGCGCAACAAGTCCAATGAGGACCAGTC
CATGGGCAATTGGCAGATCAAGCGCCAGAATGGAGATGATCCCTTGCTGACTTACCGGTTCCCACCAAAGTTCACCCTGAAGGCTGGGCAGGTGGTGACG
ATCTGGGCTGCAGGAGCTGGGGCCACCCACAGCCCCCCTACCGACCTGGTGTGGAAGGCACAGAACACCTGGGGCTGCGGGAACAGCCTGCGTACGGCTC
TCATCAACTCCACTGGGGAAGAAGTGGCCATGCGCAAGCTGGTGCGCTCAGTGACTGTGGTTGAGGACGACGAGGATGAGGATGGAGATGACCTGCTCCA
TCACCACCACGGCTCCCACTGCAGCAGCTCGGGGGACCCCGCTGAGTACAACCTGCGCTCGCGCACCGTGCTGTGCGGGACCTGCGGGCAGCCTGCCGAC
AAGGCATCTGCCAGCGGCTCAGGAGCCCAGGTGGGCGGACCCATCTCCTCTGGCTCTTCTGCCTCCAGTGTCACGGTCACTCGCAGCTACCGCAGTGTGG
GGGGCAGTGGGGGTGGCAGCTTCGGGGACAATCTGGTCACCCGCTCCTACCTCCTGGGCAACTCCAGCCCCCGAACCCAGAGCCCCCAGAACTGCAGCAT
CATGTAATCTGGGACCTGCCAGGCAGGGGTGGGGGTGGAGGCTTCCTGCGTCCTCCTCACCTCATGCCCACCCCCTGCCCTGCACGTCATGGGAGGGGGC
TTGAAGCCAAAGAAAAATAACCCTTTGGTTTTTTTCTTCTGTATTTTTTTTTCTAAGAGAAGTTATTTTCTACAGTGGTTTTATACTGAAGGAAAAACAC
AAGCAAAAAAAAAAAAAAGCATCTATCTCATCTATCTCAATCCTAATTTCTCCTCCCTTCCTTTTCCCTGCTTCCAGGAAACTCCACATCTGCCTTAAAA
CCAAAGAGGGCTTCCTCTAGAAGCCAAGGGAAAGGGGTGCTTTTATAGAGGCTAGCTTCTGCTTTTCTGCCCTGGCTGCTGCCCCCACCCCGGGGACCCT
GTGACATGGTGCCTGAGAGGCAGGCATAGAGGCTTCTCCGCCAGCCTCCTCTGGACGGCAGGCTCACTGCCAGGCCAGCCTCCGAGAGGGAGAGAGAGAG
AGAGAGGACAGCTTGAGCCGGGCCCCTGGGCTTGGCCTGCTGTGATTCCACTACACCTGGCTGAGGTTCCTCTGCCTGCCCCGCCCCCAGTCCCCACCCC
TGCCCCCAGCCCCGGGGTGAGTCCATTCTCCCAGGTACCAGCTGCGCTTGCTTTTCTGTATTTTATTTAGACAAGAGATGGGAATGAGGTGGGAGGTGGA
AGAAGGGAGAAGAAAGGTGAGTTTGAGCTGCCTTCCCTAGCTTTAGACCCTGGGTGGGCTCTGTGCAGTCACTGGAGGTTGAAGCCAAGTGGGGTGCTGG
GAGGAGGGAGAGGGAGGTCACTGGAAAGGGGAGAGCCTGCTGGCACCCACCGTGGAGGAGGAAGGCAAGAGGGGGTGGAGGGGTGTGGCAGTGGTTTTGG
CAAACGCTAAAGAGCCCTTGCCTCCCCATTTCCCATCTGCACCCCTTCTCTCCTCCCCAAATCAATACACTAGTTGTTTCT
  • refseq_LMNA.F1 (forward primer)
  • refseq_LMNA.R1 (reverse primer)
  • Single exon skipping

Frame 0

TQCSRERRTYTSQPRSRGPTAPGPDPHACQEQA
ESQPAGALRLRAVSVLRPEPRALSGTPAPRAALP
TCRPWRPRPSGAPPAAGRRPAPLRCRPPASPGC
RRRRTCRSSMIAWRSTSTVCARWKRRTQGCAFA
SPSLKRWSAARCPASRPPTRPSSGMPARPLTQ*P
RSAPACSWS*AKCVRSLRS*KRAIPRRRVT**L
LRLG*RTWRLC*TPRRPH*ALLSVRSARWRASC
MICGARWPSLRQP*VRPRSNFRMRCCGGWMLRTG
CRP*RRNWTSRRTSTVRSCVRPSAVMRPDWWRL
TMGSSVSLRAGWRMRCRNCGPSMRTRWSSIRRS
WRRLILPSWTMPGSLLRGTATWWGLPTRSCSSRA
SASTASLPSSASSRSSWQPRRRSFETWRTHWPV
SGTPAGGCWRKRSGRWPRCGQGCSSSWTSTRSF
WTSSWPWTWRSTPTASSWRARRRGYACPPALPRS
AAVAVLPLTHPRHRVGAASPKSANWSPLRAAAA
SHSTHALAGAWPWRRWMRRASLSGCATSPMRTS
PWAIGRSSARMEMIPC*LTGSHQSSP*RLGRW*R
SGLQELGPPTAPLPTWCGRHRTPGAAGTACVRL
SSTPLGKKWPCASWCAQ*LWLRTTRMRMEMTCS
ITTTAPTAAARGTPLSTTCARAPCCAGPAGSLPT
RHLPAAQEPRWADPSPLALLPPVSRSLAATAVW
GAVGVAASGTIWSPAPTSWATPAPEPRAPRTAA
SCNLGPARQGWGWRLPASSSPHAHPLPCTSWEGA
*SQRKITLWFFSSVFFFLREVIFYSGFILKEKH
KQKKKKASISSISILISPPFLFPASRKLHICLK
TKEGFL*KPRERGAFIEASFCFSALAAAPTPGTL
*HGA*EAGIEASPPASSGRQAHCQASLREGERE
REDSLSRAPGLGLL*FHYTWLRFLCLPRPQSPP
LPPAPG*VHSPRYQLRLLFCILFRQEMGMRWEVE
EGRRKVSLSCLP*L*TLGGLCAVTGG*SQVGCW
EEGEGGHWKGESLLAPTVEEEGKRGWRGVAVVL
ANAKEPLPPHFPSAPLLSSPNQYTSCF

Frame 1

LSVRGSAAPTPANPDPEVRQRPAQIPTPARSKP
RASRPAHSDSEQSLSFDPSPAPFPGPLPRGQRC
QPAGHGDPVPAARHPQRGAGQLHSAVAHPHHPAA
GEGGPAGAQ*SLGGLHRPCALAGNGERRAAPSH
HRV*RGGQPRGVRHQGRLRGRARGCPQDP*LSS
QGARPPAAGAEQSA*GV*GAESAQYQEGG*PDSC
SGSAEGPGGSAELQGGRTEHCSQ*EAHAGGRAA
*SAGPGGQA*GSPR*GQEATSG*DAAAGGC*EQ
AADHEGGTGLPEEHLQ*GAA*DQAPS*DPTGGD*
QWEAA*V*EPAGGCAAGTAGPA*GPGGAV*EGA
GEDLFCQAGQCQAVC*EEQQPGGGCPRGAAAVA
HPHRQPLCPAQPAPEAAGSQGGEASRPGGLTGP*
AGHQPAAAGGKGAGDGRDAGKDAAAAGRVPGAS
GHQAGPGHGDPRLPQALGGRGGEATPVPQPYLA
AQPWPCFLSLIPDTGWGQRHQKAQTGVH*EPQQL
LTARTH*RARGRGGGG*GGQVCPAAQQVQ*GPV
HGQLADQAPEWR*SLADLPVPTKVHPEGWAGGD
DLGCRSWGHPQPPYRPGVEGTEHLGLREQPAYGS
HQLHWGRSGHAQAGALSDCG*GRRG*GWR*PAP
SPPRLPLQQLGGPR*VQPALAHRAVRDLRAACR
QGICQRLRSPGGRTHLLWLFCLQCHGHSQLPQCG
GQWGWQLRGQSGHPLLPPGQLQPPNPEPPELQH
HVIWDLPGRGGGGGFLRPPHLMPTPCPARHGRG
LEAKEK*PFGFFLLYFFF*EKLFSTVVLY*RKNT
SKKKKKHLSHLSQS*FLLPSFSLLPGNSTSALK
PKRASSRSQGKGVLL*RLASAFLPWLLPPPRGP
CDMVPERQA*RLLRQPPLDGRLTARPASERERER
ERTA*AGPLGLACCDSTTPG*GSSACPAPSPHP
CPQPRGESILPGTSCACFSVFYLDKRWE*GGRW
KKGEER*V*AAFPSFRPWVGSVQSLEVEAKWGAG
RREREVTGKGRACWHPPWRRKARGGGGVWQWFW
QTLKSPCLPISHLHPFSPPQINTLVVS

Frame 2

SVFAGAPHLHQPTQIPRSDSARPRSPRLPGASR
EPAGRRTPTPSSLCPSTRAPRPFRDPCPAGSAA
NLPAMETPSQRRATRSGAQASSTPLSPTRITRL
QEKEDLQELNDRLAVYIDRVRSLETENAGLRLRI
TESEEVVSREVSGIKAAYEAELGDARKTLDSVA
KERARLQLELSKVREEFKELKARNTKKEGDLIA
AQARLKDLEALLNSKEAALSTALSEKRTLEGELH
DLRGQVAKLEAALGEAKKQLQDEMLRRVDAENR
LQTMKEELDFQKNIYSEELRETKRRHETRLVEI
DNGKQREFESRLADALQELRAQHEDQVEQYKKEL
EKTYSAKLDNARQSAERNSNLVGAAHEELQQSR
IRIDSLSAQLSQLQKQLAAKEAKLRDLEDSLAR
ERDTSRRLLAEKEREMAEMRARMQQQLDEYQELL
DIKLALDMEIHAYRKLLEGEEERLRLSPSPTSQ
RSRGRASSHSSQTQGGGSVTKKRKLESTESRSS
FSQHARTSGRVAVEEVDEEGKFVRLRNKSNEDQS
MGNWQIKRQNGDDPLLTYRFPPKFTLKAGQVVT
IWAAGAGATHSPPTDLVWKAQNTWGCGNSLRTA
LINSTGEEVAMRKLVRSVTVVEDDEDEDGDDLLH
HHHGSHCSSSGDPAEYNLRSRTVLCGTCGQPAD
KASASGSGAQVGGPISSGSSASSVTVTRSYRSV
GGSGGGSFGDNLVTRSYLLGNSSPRTQSPQNCSI
M*SGTCQAGVGVEASCVLLTSCPPPALHVMGGG
LKPKKNNPLVFFFCIFFSKRSYFLQWFYTEGKT
QAKKKKSIYLIYLNPNFSSLPFPCFQETPHLP*N
QRGLPLEAKGKGCFYRG*LLLFCPGCCPHPGDP
VTWCLRGRHRGFSASLLWTAGSLPGQPPRGRER
ERGQLEPGPWAWPAVIPLHLAEVPLPAPPPVPTP
APSPGVSPFSQVPAALAFLYFI*TRDGNEVGGG
RREKKGEFELPSLALDPGWALCSHWRLKPSGVL
GGGRGRSLERGEPAGTHRGGGRQEGVEGCGSGFG
KR*RALASPFPICTPSLLPKSIH*LF

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