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Sequences

Sequence NM_001031740

GGGAAGCGCGCGGCCGGGCGGGCGGCCATGGCGCGGCACGCTGGGAGGTAGCGCGGCGGCTGCAGGAGCGCACAGTCGGCCATGGCCCGGCGGCGGCGCC
GCGCCTGCATCGCTCTGTTCCTGGTGCTGCTCTTCGCCTTCGGCACCCTCATGGGTCTGCGCACGCTCAAGGCTCCGGACGGACTCCCGGCGCTGGGCCC
GGGCCTGGAGCTGGCGCCCTTTGAGCGACGCCCAGAGGGGGCCCCCGCGCCCGCTGCCAGGGCCCCGGCAGCCCCTGCCGCGCCGCCCCCGCCGCCGCCG
CCGCCCCGCACCGCGGACCCTGGCGGCTCCCCTGGGCCGGCACCCGCGGAGGCCGAGCCCGCCCCCGTGCAGAGCCTGCGCGTCTACTCGGACCTGCACG
CCTTCTACTACTCGTGGTACGGGAGCCCGCGGCGCGAGGGCCACTACATTCACTGGGACCACGTCATGGTGCCGCACTGGGACCCCAAGATCTCGGCCAG
CTACCCCCGCGGCCGCCACAGCCCCCCAGACGACTTGGGCTCCAGCTTCTACCCGGAGCTGGGGCCCTACAGCTCCCGGGACCCCGAAGTGCTGCGGGAG
CATATGACCCAGCTCAAGGAAGCCGCCATCGGCGTCCTGGTCCTGTCCTGGTACCCACCTGGCATGGCTGATGATAACGGGGAGCCCTCAGATGACCTGG
TGCCCGCCATTCTGGACACCGCCCATCAGTACAGCATCCAGGTGGCCTTCCACATCCAACCCTACAAGGGCCGGGATGACATCACTGTACATGACAACAT
CAAGTACATCATTGACACAACTGGAAAGCTGTGAAGAACTTTTGTGATGCCAACAACCTCATGTTCATCCCCAGTGTGGGGCCTGGCTACATAGACACCA
GCATTCGGCCCTGGAACAACCACAATACGCGCAACAGGGTCAATGGCAAGTACTATGAGACGGCCCTGCAGGCGGCCCTGACAGTGAGGCCCGAGATCGT
TTCCATTACCTCCTTCAATGAGTGGCACGAGGGCACCCAGATTGAGAAGGCCATTCCCAAGAAGACACCCACCCGCCTGTATTTGGACTACCTGCCTCAC
CAGCCCAGCCTGTACCTGGAGCTGACACGCCGCTGGGCGGAGCACTTCATCAAAGAGAAGGAGCAGTGGCTCATGTGAGGGGCCTGTAAATGGGCGTGAG
GTGCTGATGTCCTTGCCTTGCTGGAAGATGTCACCATGTGGGGTTCAGCTGAGGTTGTAGCCACTCACTCGTTCCCAGGTCAGAGGTCAGCAGATGGGTG
TTTCTGGGTGGGCCGTCAGGCATGGGCCTGTGCAACACAGAGCCCGTTCCTCAGGCGAGTGGTGCTGAGGTGCTCTGTGGTGATGGGAACGGCAGAGGCT
GGCAGGTGACTGAACTTAGCCCAGGGCAGCTCCACATCCTGGGAACACTTTCATGTAACCCCTTCTAGTTTTGAACTCTGCAGCAGGCTGGTGCTGTGTA
GTGGCCACCCAGTCACCACCCTTGGAAGGGTGTCAGGGTCTGGGCTCGCATGCACCCTGCTCCCTTCTGCCAGCCTGCATCCTCTCCTCAGGCCTCCTTC
CCACATCATCTGTCTTCTCTAAGTTAGGGAACCATATTTGAGACTTTCAAAAAGGGAACTTCTAGGTTTAAGCTCCTCCCAGTAGATTCCTGAACCCAAT
TATCAGGAAATCATCCTGAGCACTCACAGGTTCATTTAACACTCACTCATCAAGCACCTTCCTATGTGCTAGGTGCTGGGGAAAACTTGACCAAGGAAGA
GTTCCTGTCCTGAAGCTTCCAGGACCCAGCTTTCCTTTTCTGGTGTGGCCTTGTAGCTAGTGCCTGGGCACAGGTGTTTTTCTTTTTGCAGTTTTACCTA
GTGCTGGGAGTTCAGTTCTTTTTCCTCTAGAAAAATACCTCTGTGCTCCAGAGCCTAATTTTTCCCAGATGCATATTTAGCTCTAGGGAGAGGACTAGGA
GGAAATCCCCCTCCCTTTAGCTGCCTGAACTGACTGAGGCCCACTCACTAGAGCCATGTTCAGTGCTACTGTGATTAGTAGTAATTAAATATGAACTGGT
ATTCTCAAGTAAGCATTCCTTTTGCTCTCTTTAAGACCTCACAGATTCTGACCTTAGATTCTGTGACAAACTGATACAGGAGCTGGGCTGGCTATGGCTT
TACCACAACAAGTAGGTTTGCTTAAGAAATTACTAAACAATGGCTGGGCGTGGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGCCGAGATGGGCGG
ATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACAGGGTGAAACCACGTCTCTACTAAAAATACAAAAAAATTAGCCAGGCGTAGTGGTGGGCGCCT
GTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGG
GCGACAGAGCGAGACTCCGTCTC
  • refseq_MANEAL.F1 (forward primer)
  • refseq_MANEAL.R1 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

GKRAAGRAAMARHAGR*RGGCRSAQSAMARRRR
RACIALFLVLLFAFGTLMGLRTLKAPDGLPALGP
GLELAPFERRPEGAPAPAARAPAAPAAPPPPPP
PPRTADPGGSPGPAPAEAEPAPVQSLRVYSDLH
AFYYSWYGSPRREGHYIHWDHVMVPHWDPKISAS
YPRGRHSPPDDLGSSFYPELGPYSSRDPEVLRE
HMTQLKEAAIGVLVLSWYPPGMADDNGEPSDDL
VPAILDTAHQYSIQVAFHIQPYKGRDDITVHDNI
KYIIDTTGKL*RTFVMPTTSCSSPVWGLAT*TP
AFGPGTTTIRATGSMASTMRRPCRRP*Q*GPRS
FPLPPSMSGTRAPRLRRPFPRRHPPACIWTTCLT
SPACTWS*HAAGRSTSSKRRSSGSCEGPVNGRE
VLMSLPCWKMSPCGVQLRL*PLTRSQVRGQQMG
VSGWAVRHGPVQHRARSSGEWC*GALW*WERQRL
AGD*T*PRAAPHPGNTFM*PLLVLNSAAGWCCV
VATQSPPLEGCQGLGSHAPCSLLPACILSSGLL
PTSSVFSKLGNHI*DFQKGNF*V*APPSRFLNPI
IRKSS*ALTGSFNTHSSSTFLCARCWGKLDQGR
VPVLKLPGPSFPFLVWPCS*CLGTGVFLFAVLP
SAGSSVLFPLEKYLCAPEPNFSQMHI*L*GED*E
EIPLPLAA*TD*GPLTRAMFSATVISSN*I*TG
ILK*AFLLLSLRPHRF*P*IL*QTDTGAGLAMA
LPQQVGLLKKLLNNGWAWWLTPVIPALWEAEMGG
SRGQEIETILANRVKPRLY*KYKKISQA*WWAP
VVPATWEAEAGEWREPGRRSLQ*AEITPLHSSL
GDRARLRL

Frame 1

GSARPGGRPWRGTLGGSAAAAGAHSRPWPGGGA
APASLCSWCCSSPSAPSWVCARSRLRTDSRRWA
RAWSWRPLSDAQRGPPRPLPGPRQPLPRRPRRRR
RPAPRTLAAPLGRHPRRPSPPPCRACASTRTCT
PSTTRGTGARGARATTFTGTTSWCRTGTPRSRP
ATPAAATAPQTTWAPASTRSWGPTAPGTPKCCGS
I*PSSRKPPSASWSCPGTHLAWLMITGSPQMTW
CPPFWTPPISTASRWPSTSNPTRAGMTSLYMTT
SSTSLTQLESCEELL*CQQPHVHPQCGAWLHRHQ
HSALEQPQYAQQGQWQVL*DGPAGGPDSEARDR
FHYLLQ*VARGHPD*EGHSQEDTHPPVFGLPAS
PAQPVPGADTPLGGALHQREGAVAHVRGL*MGVR
C*CPCLAGRCHHVGFS*GCSHSLVPRSEVSRWV
FLGGPSGMGLCNTEPVPQASGAEVLCGDGNGRG
WQVTELSPGQLHILGTLSCNPF*F*TLQQAGAV*
WPPSHHPWKGVRVWARMHPAPFCQPASSPQASF
PHHLSSLS*GTIFETFKKGTSRFKLLPVDS*TQ
LSGNHPEHSQVHLTLTHQAPSYVLGAGENLTKEE
FLS*SFQDPAFLFWCGLVASAWAQVFFFLQFYL
VLGVQFFFL*KNTSVLQSLIFPRCIFSSRERTR
RKSPSL*LPELTEAHSLEPCSVLL*LVVIKYELV
FSSKHSFCSL*DLTDSDLRFCDKLIQELGWLWL
YHNK*VCLRNY*TMAGRGGSLL*SQHFGRPRWA
DHEVRRSRPSWLTG*NHVSTKNTKKLARRSGGRL
*SQLLGRLRQENGVNPGGGACSEPRSRHCTPAW
ATERDSV

Frame 2

EARGRAGGHGAARWEVARRLQERTVGHGPAAAP
RLHRSVPGAALRLRHPHGSAHAQGSGRTPGAGP
GPGAGAL*ATPRGGPRARCQGPGSPCRAAPAAA
AAPHRGPWRLPWAGTRGGRARPRAEPARLLGPAR
LLLLVVREPAARGPLHSLGPRHGAALGPQDLGQ
LPPRPPQPPRRLGLQLLPGAGALQLPGPRSAAG
AYDPAQGSRHRRPGPVLVPTWHG***RGALR*PG
ARHSGHRPSVQHPGGLPHPTLQGPG*HHCT*QH
QVHH*HNWKAVKNFCDANNLMFIPSVGPGYIDT
SIRPWNNHNTRNRVNGKYYETALQAALTVRPEIV
SITSFNEWHEGTQIEKAIPKKTPTRLYLDYLPH
QPSLYLELTRRWAEHFIKEKEQWLM*GACKWA*
GADVLALLEDVTMWGSAEVVATHSFPGQRSADGC
FWVGRQAWACATQSPFLRRVVLRCSVVMGTAEA
GR*LNLAQGSSTSWEHFHVTPSSFELCSRLVLC
SGHPVTTLGRVSGSGLACTLLPSASLHPLLRPPS
HIICLL*VREPYLRLSKRELLGLSSSQ*IPEPN
YQEIILSTHRFI*HSLIKHLPMC*VLGKT*PRK
SSCPEASRTQLSFSGVAL*LVPGHRCFSFCSFT*
CWEFSSFSSRKIPLCSRA*FFPDAYLALGRGLG
GNPPPFSCLN*LRPTH*SHVQCYCD***LNMNW
YSQVSIPFALFKTSQILTLDSVTN*YRSWAGYGF
TTTSRFA*EITKQWLGVVAHSCNPSTLGGRDGR
ITRSGDRDHPG*QGETTSLLKIQKN*PGVVVGA
CSPSYLGG*GRRMA*TREAELAVSRDHATALQPG
RQSETPS

Sequence NM_152496

AGTCTAAAGCCTGGCTCCCTTCCGGCCTGGCGCGCTACGGTTCCCGCAGGCGCTCCGCTTCAGCACCGCGGGCGTGGACAGCTCCGGGGCGCGAGGCTCT
GGGACTCATCTGCAGGAAGTGAACCTGGCAGGAGGCTTGCTTCAGGTTTTTAGGAACCATTTTTGCAATTGGAGATGTTTGTGAGGAAAAAAATCTCTGT
TGAGGGGGGTACTGTGTGTCTCTGAAGTGGCCTCTGTGTTGCGTCTCAGGCGTCCTGGTCCTGTCCTGGTACCCACCTGGCATGGCTGATGATAACGGGG
AGCCCTCAGATGACCTGGTGCCCGCCATTCTGGACACCGCCCATCAGTACAGCATCCAGGTATGGCTCCCATGGTGCATTTTACCGCTATAAGAACAGCA
TGGGCAAGAGCCTCCCACTCTTTTATATCTACGACTCATACCTGACGTCCCCTGAGGCCTGGGCCCACCTCCTGACACCAAACGGGCCCCATTCGATCCG
CAACACGCCCTACGATGGGGTCTTCATAGCGCTGCTGGTGGAGGAGGGCCACACCCACGATATCCTGGCCGCCGGATTTGACGGCATGTACACCTACTTT
GCCTCCAATGGTTTCTCCTTTGGTTCTTCCCATCAGAACTGGAAAGCTGTGAAGAACTTTTGTGATGCCAACAACCTCATGTTCATCCCCAGTGTGGGGC
CTGGCTACATAGACACCAGCATTCGGCCCTGGAACAACCACAATACGCGCAACAGGGTCAATGGCAAGTACTATGAGACGGCCCTGCAGGCGGCCCTGAC
AGTGAGGCCCGAGATCGTTTCCATTACCTCCTTCAATGAGTGGCACGAGGGCACCCAGATTGAGAAGGCCATTCCCAAGAAGACACCCACCCGCCTGTAT
TTGGACTACCTGCCTCACCAGCCCAGCCTGTACCTGGAGCTGACACGCCGCTGGGCGGAGCACTTCATCAAAGAGAAGGAGCAGTGGCTCATGTGAGGGG
CCTGTAAATGGGCGTGAGGTGCTGATGTCCTTGCCTTGCTGGAAGATGTCACCATGTGGGGTTCAGCTGAGGTTGTAGCCACTCACTCGTTCCCAGGTCA
GAGGTCAGCAGATGGGTGTTTCTGGGTGGGCCGTCAGGCATGGGCCTGTGCAACACAGAGCCCGTTCCTCAGGCGAGTGGTGCTGAGGTGCTCTGTGGTG
ATGGGAACGGCAGAGGCTGGCAGGTGACTGAACTTAGCCCAGGGCAGCTCCACATCCTGGGAACACTTTCATGTAACCCCTTCTAGTTTTGAACTCTGCA
GCAGGCTGGTGCTGTGTAGTGGCCACCCAGTCACCACCCTTGGAAGGGTGTCAGGGTCTGGGCTCGCATGCACCCTGCTCCCTTCTGCCAGCCTGCATCC
TCTCCTCAGGCCTCCTTCCCACATCATCTGTCTTCTCTAAGTTAGGGAACCATATTTGAGACTTTCAAAAAGGGAACTTCTAGGTTTAAGCTCCTCCCAG
TAGATTCCTGAACCCAATTATCAGGAAATCATCCTGAGCACTCACAGGTTCATTTAACACTCACTCATCAAGCACCTTCCTATGTGCTAGGTGCTGGGGA
AAACTTGACCAAGGAAGAGTTCCTGTCCTGAAGCTTCCAGGACCCAGCTTTCCTTTTCTGGTGTGGCCTTGTAGCTAGTGCCTGGGCACAGGTGTTTTTC
TTTTTGCAGTTTTACCTAGTGCTGGGAGTTCAGTTCTTTTTCCTCTAGAAAAATACCTCTGTGCTCCAGAGCCTAATTTTTCCCAGATGCATATTTAGCT
CTAGGGAGAGGACTAGGAGGAAATCCCCCTCCCTTTAGCTGCCTGAACTGACTGAGGCCCACTCACTAGAGCCATGTTCAGTGCTACTGTGATTAGTAGT
AATTAAATATGAACTGGTATTCTCAAGTAAGCATTCCTTTTGCTCTCTTTAAGACCTCACAGATTCTGACCTTAGATTCTGTGACAAACTGATACAGGAG
CTGGGCTGGCTATGGCTTTACCACAACAAGTAGGTTTGCTTAAGAAATTACTAAACAATGGCTGGGCGTGGTGGCTCACTCCTGTAATCCCAGCACTTTG
GGAGGCCGAGATGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACAGGGTGAAACCACGTCTCTACTAAAAATACAAAAAAATTAGCCAG
GCGTAGTGGTGGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCACGC
CACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCCGTCTC
  • refseq_MANEAL.F1 (forward primer)
  • refseq_MANEAL.R1 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

SLKPGSLPAWRATVPAGAPLQHRGRGQLRGARL
WDSSAGSEPGRRLASGF*EPFLQLEMFVRKKISV
EGGTVCL*SGLCVASQASWSCPGTHLAWLMITG
SPQMTWCPPFWTPPISTASRYGSHGAFYRYKNS
MGKSLPLFYIYDSYLTSPEAWAHLLTPNGPHSIR
NTPYDGVFIALLVEEGHTHDILAAGFDGMYTYF
ASNGFSFGSSHQNWKAVKNFCDANNLMFIPSVG
PGYIDTSIRPWNNHNTRNRVNGKYYETALQAALT
VRPEIVSITSFNEWHEGTQIEKAIPKKTPTRLY
LDYLPHQPSLYLELTRRWAEHFIKEKEQWLM*G
ACKWA*GADVLALLEDVTMWGSAEVVATHSFPGQ
RSADGCFWVGRQAWACATQSPFLRRVVLRCSVV
MGTAEAGR*LNLAQGSSTSWEHFHVTPSSFELC
SRLVLCSGHPVTTLGRVSGSGLACTLLPSASLHP
LLRPPSHIICLL*VREPYLRLSKRELLGLSSSQ
*IPEPNYQEIILSTHRFI*HSLIKHLPMC*VLG
KT*PRKSSCPEASRTQLSFSGVAL*LVPGHRCFS
FCSFT*CWEFSSFSSRKIPLCSRA*FFPDAYLA
LGRGLGGNPPPFSCLN*LRPTH*SHVQCYCD**
*LNMNWYSQVSIPFALFKTSQILTLDSVTN*YRS
WAGYGFTTTSRFA*EITKQWLGVVAHSCNPSTL
GGRDGRITRSGDRDHPG*QGETTSLLKIQKN*P
GVVVGACSPSYLGG*GRRMA*TREAELAVSRDHA
TALQPGRQSETPS

Frame 1

V*SLAPFRPGALRFPQALRFSTAGVDSSGARGS
GTHLQEVNLAGGLLQVFRNHFCNWRCL*GKKSL
LRGVLCVSEVASVLRLRRPGPVLVPTWHG***RG
ALR*PGARHSGHRPSVQHPGMAPMVHFTAIRTA
WARASHSFISTTHT*RPLRPGPTS*HQTGPIRS
ATRPTMGSS*RCWWRRATPTISWPPDLTACTPTL
PPMVSPLVLPIRTGKL*RTFVMPTTSCSSPVWG
LAT*TPAFGPGTTTIRATGSMASTMRRPCRRP*
Q*GPRSFPLPPSMSGTRAPRLRRPFPRRHPPACI
WTTCLTSPACTWS*HAAGRSTSSKRRSSGSCEG
PVNGREVLMSLPCWKMSPCGVQLRL*PLTRSQV
RGQQMGVSGWAVRHGPVQHRARSSGEWC*GALW*
WERQRLAGD*T*PRAAPHPGNTFM*PLLVLNSA
AGWCCVVATQSPPLEGCQGLGSHAPCSLLPACI
LSSGLLPTSSVFSKLGNHI*DFQKGNF*V*APPS
RFLNPIIRKSS*ALTGSFNTHSSSTFLCARCWG
KLDQGRVPVLKLPGPSFPFLVWPCS*CLGTGVF
LFAVLPSAGSSVLFPLEKYLCAPEPNFSQMHI*L
*GED*EEIPLPLAA*TD*GPLTRAMFSATVISS
N*I*TGILK*AFLLLSLRPHRF*P*IL*QTDTG
AGLAMALPQQVGLLKKLLNNGWAWWLTPVIPALW
EAEMGGSRGQEIETILANRVKPRLY*KYKKISQ
A*WWAPVVPATWEAEAGEWREPGRRSLQ*AEIT
PLHSSLGDRARLRL

Frame 2

SKAWLPSGLARYGSRRRSASAPRAWTAPGREAL
GLICRK*TWQEACFRFLGTIFAIGDVCEEKNLC
*GGYCVSLKWPLCCVSGVLVLSWYPPGMADDNG
EPSDDLVPAILDTAHQYSIQVWLPWCILPL*EQH
GQEPPTLLYLRLIPDVP*GLGPPPDTKRAPFDP
QHALRWGLHSAAGGGGPHPRYPGRRI*RHVHLL
CLQWFLLWFFPSELESCEELL*CQQPHVHPQCGA
WLHRHQHSALEQPQYAQQGQWQVL*DGPAGGPD
SEARDRFHYLLQ*VARGHPD*EGHSQEDTHPPV
FGLPASPAQPVPGADTPLGGALHQREGAVAHVRG
L*MGVRC*CPCLAGRCHHVGFS*GCSHSLVPRS
EVSRWVFLGGPSGMGLCNTEPVPQASGAEVLCG
DGNGRGWQVTELSPGQLHILGTLSCNPF*F*TLQ
QAGAV*WPPSHHPWKGVRVWARMHPAPFCQPAS
SPQASFPHHLSSLS*GTIFETFKKGTSRFKLLP
VDS*TQLSGNHPEHSQVHLTLTHQAPSYVLGAGE
NLTKEEFLS*SFQDPAFLFWCGLVASAWAQVFF
FLQFYLVLGVQFFFL*KNTSVLQSLIFPRCIFS
SRERTRRKSPSL*LPELTEAHSLEPCSVLL*LVV
IKYELVFSSKHSFCSL*DLTDSDLRFCDKLIQE
LGWLWLYHNK*VCLRNY*TMAGRGGSLL*SQHF
GRPRWADHEVRRSRPSWLTG*NHVSTKNTKKLAR
RSGGRL*SQLLGRLRQENGVNPGGGACSEPRSR
HCTPAWATERDSV

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