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Sequences

Sequence NM_004524

GGAGGTGAGCAGGAAGGAGACGGCCGCCCAGCAGCCCGTGGGCAGGCGCGGCGGAGCGAGCGGGGCCGGCGGCGGGCGCCGAGGGACGCCGAGGCCTCGG GCGGGGGCTGGCCCGGGGTTCCAGGTCTCCAGTGGGGGCTGCAGACTAAGCAAAATGAGGCGGTTCCTGAGGCCAGGGCATGACCCTGTGCGGGAGAGGC TCAAGCGGGACCTGTTCCAGTTTAACAAGACGGTGGAGCATGGCTTCCCGCACCAGCCCAGCGCCCTCGGCTACAGCCCGTCCCTGCGCATCCTGGCCAT CGGCACCCGTTCTGGAGCCATCAAGCTCTACGGAGCCCCAGGCGTGGAGTTCATGGGGCTGCACCAGGAGAACAACGCTGTGACGCAGATCCACCTCCTG CCCGGCCAGTGCCAGCTGGTCACCCTGCTGGATGACAACAGCCTGCACCTTTGGAGCCTGAAGGTCAAGGGCGGGGCATCGGAGCTGCAGGAGGATGAGA GCTTCACACTGCGTGGACCCCCAGGGGCTGCCCCCAGTGCCACACAGATCACCGTGGTCCTGCCACATTCCTCCTGCGAGCTGCTCTACCTGGGCACCGA GAGTGGCAACGTGTTTGTGGTGCAGCTGCCAGCTTTTCGTGCGCTGGAGGACCGGACCATCAGCTCGGACGCGGTGCTGCAGCGGTTGCCAGAGGAGGCC CGCCACCGGCGTGTGTTCGAGATGGTGGAGGCACTGCAGGAGCACCCTCGAGACCCCAACCAGATCCTGATCGGCTACAGCCGAGGCCTCGTTGTCATCT GGGACCTACAGGGCAGCCGCGTGCTCTACCACTTCCTCAGCAGCCAGCAACTGGAGAACATCTGGTGGCAGCGGGACGGCCGCCTGCTCGTCAGCTGTCA CTCTGACGGCAGCTACTGCCAGTGGCCCGTGTCCAGCGAAGCCCAGCAACCAGAGCCCCTCCGCAGCCTCGTGCCTTACGGTCCCTTTCCTTGCAAAGCG ATTACCAGAATCCTCTGGCTGACCACTAGGCAGGGGTTGCCCTTCACCATCTTCCAGGGTGGCATGCCACGGGCCAGCTACGGGGACCGCCACTGCATCT CAGTGATCCACGATGGCCAGCAGACGGCCTTCGACTTCACCTCCCGTGTCATCGGCTTCACTGTCCTCACAGAGGCAGACCCTGCAGCCACCTTTGACGA CCCCTATGCCCTGGTGGTGCTGGCTGAGGAGGAGCTGGTGGTGATTGACCTGCAGACAGCAGGCTGGCCACCGGTCCAGCTGCCCTACCTGGCTTCTCTG CACTGTTCCGCCATCACCTGCTCTCACCACGTCTCCAACATCCCGCTGAAGCTGTGGGAGCGGATCATTGCCGCCGGCAGCCGGCAGAACGCACACTTCT CCACCATGGAGTGGCCAATTGATGGTGGCACCAGCCTGACCCCAGCCCCACCCCAGAGGGACCTGCTGCTCACAGGGCACGAGGACGGCACGGTGCGGTT CTGGGATGCCTCGGGTGTCTGCCTGCGGCTGCTCTACAAACTCAGCACTGTGCGCGTGTTCCTCACCGACACGGACCCCAACGAGAACTTCAGTGCCCAG GGCGAGGACGAGTGGCCCCCACTCCGCAAGGTGGGCTCCTTTGACCCCTACAGTGATGACCCCCGGCTGGGCATCCAGAAGATCTTCCTCTGCAAGTACA GCGGCTACCTGGCTGTGGCAGGCACGGCAGGGCAGGTGCTGGTACTGGAACTGAATGACGAGGCAGCGGAGCAGGCTGTGGAGCAGGTGGAGGCCGACCT GCTGCAGGACCAAGAGGGCTACCGCTGGAAGGGGCACGAGCGCCTGGCAGCCCGCTCAGGGCCCGTGCGCTTTGAGCCTGGCTTTCAGCCCTTCGTGTTG GTGCAGTGTCAGCCCCCGGCTGTGGTCACCTCCTTGGCCCTGCACTCTGAGTGGCGGCTCGTGGCCTTCGGCACCAGCCATGGCTTTGGCCTCTTTGACC ACCAGCAGCGGCGGCAGGTCTTTGTTAAGTGCACACTGCACCCCAGTGACCAGCTGGCCTTGGAGGGCCCACTCTCCCGCGTCAAGTCCCTCAAGAAGTC CTTGCGTCAGTCATTCCGCCGGATGCGTCGGAGCCGGGTGTCCAGCCGGAAGCGGCACCCGGCTGGCCCCCCAGGAGAGGCACAGGAGGGGAGTGCCAAG GCTGAGCGGCCAGGCCTCCAGAACATGGAGCTGGCGCCTGTGCAGCGCAAGATCGAGGCTCGCTCGGCAGAGGACTCCTTCACAGGCTTCGTCCGGACCC TGTACTTTGCTGACACCTACCTGAAGGACAGCTCCCGGCACTGCCCCTCGCTGTGGGCTGGCACCAATGGGGGCACCATCTATGCCTTCTCCCTGCGTGT GCCTCCCGCCGAGCGGAGAATGGATGAGCCTGTGCGGGCAGAGCAGGCCAAGGAGATCCAGCTGATGCACCGGGCGCCGGTGGTGGGCATCCTGGTGCTC GACGGACACAGCGTACCCCTTCCCGAGCCCCTCGAAGTGGCCCATGATCTGTCGAAGAGCCCTGACATGCAGGGAAGCCACCAGCTGCTCGTCGTATCAG AGGAGCAGTTCAAGGTGTTCACGCTGCCCAAGGTGAGTGCCAAGCTGAAGTTGAAGCTGACGGCCCTGGAGGGCTCAAGAGTGCGGCGGGTCAGCGTGGC CCACTTCGGCAGTCGTCGAGCCGAGGACTACGGGGAGCACCACCTGGCAGTCCTTACCAACCTGGGCGACATCCAGGTGGTCTCGCTGCCCCTGCTCAAG CCCCAGGTGCGCTACAGCTGCATCCGCCGGGAGGACGTCAGTGGCATCGCCTCCTGCGTCTTCACCAAATATGGCCAAGGCTTCTACCTGATCTCACCCT CGGAGTTTGAGCGCTTCTCTCTCTCCACCAAGTGGCTGGTGGAGCCCCGGTGTCTGGTGGATTCAGCAGAAACCAAGAACCACCGCCCTGGTAACGGTGC GGGCCCCAAGAAGGCCCCGAGCCGAGCCAGGAACTCAGGGACTCAGAGTGATGGCGAGGAGAAGCAGCCCGGCCTGGTGATGGAGCGCGCTCTGCTCAGT GATGAGAGAGCGGCAACTGGCGTTCACATCGAGCCGCCGTGGGGTGCAGCCTCAGCAATGGCGGAGCAGAGTGAGTGGCTGAGCGTCCAGGCTGCGCGAT GAGCACACACTACTACTGATGGCCTTTCGGGGGTCCCTGCCCCAACCGGAGAGGCCGGTGCACAGGGCCCCGCCAGGGGCTGGGGGCATCCCGGCTTCCA CAATGCAGCTGCTCTGGGCCTCGGGAGAGGAGAGACCCCAGTCCCCTGGGCTGCCCTTCCCGGGCCTCGTCTGTCTGGGTCCTTTGGTCAATGTTGCACA GTTTTTATTGCTCCCATCCCTTTTTGTAGTGGGCTGGGTTTTAAGTTATAAATGTTAACTGCCTCTGGGTGAAAAAGTTTTTAATAAACACCTATTACCT CTTGA

refseq_LLGL2.F1 (forward primer)
refseq_LLGL2.R1 (reverse primer)
Single exon skipping

Frame 0

GGEQEGDGRPAARGQARRSERGRRRAPRDAEAS GGGWPGVPGLQWGLQTKQNEAVPEARA*PCAGEA QAGPVPV*QDGGAWLPAPAQRPRLQPVPAHPGH RHPFWSHQALRSPRRGVHGAAPGEQRCDADPPP ARPVPAGHPAG*QQPAPLEPEGQGRGIGAAGG*E LHTAWTPRGCPQCHTDHRGPATFLLRAALPGHR EWQRVCGAAASFSCAGGPDHQLGRGAAAVARGG PPPACVRDGGGTAGAPSRPQPDPDRLQPRPRCHL GPTGQPRALPLPQQPATGEHLVAAGRPPARQLS L*RQLLPVARVQRSPATRAPPQPRALRSLSLQS DYQNPLADH*AGVALHHLPGWHATGQLRGPPLHL SDPRWPADGLRLHLPCHRLHCPHRGRPCSHL*R PLCPGGAG*GGAGGD*PADSRLATGPAALPGFS ALFRHHLLSPRLQHPAEAVGADHCRRQPAERTLL HHGVAN*WWHQPDPSPTPEGPAAHRARGRHGAV LGCLGCLPAAALQTQHCARVPHRHGPQRELQCP GRGRVAPTPQGGLL*PLQ**PPAGHPEDLPLQVQ RLPGCGRHGRAGAGTGTE*RGSGAGCGAGGGRP AAGPRGLPLEGARAPGSPLRARAL*AWLSALRV GAVSAPGCGHLLGPAL*VAARGLRHQPWLWPL*P PAAAAGLC*VHTAPQ*PAGLGGPTLPRQVPQEV LASVIPPDASEPGVQPEAAPGWPPRRGTGGECQ G*AARPPEHGAGACAAQDRGSLGRGLLHRLRPDP VLC*HLPEGQLPALPLAVGWHQWGHHLCLLPAC ASRRAENG*ACAGRAGQGDPADAPGAGGGHPGA RRTQRTPSRAPRSGP*SVEEP*HAGKPPAARRIR GAVQGVHAAQGECQAEVEADGPGGLKSAAGQRG PLRQSSSRGLRGAPPGSPYQPGRHPGGLAAPAQ APGALQLHPPGGRQWHRLLRLHQIWPRLLPDLTL GV*ALLSLHQVAGGAPVSGGFSRNQEPPPW*RC GPQEGPEPSQELRDSE*WRGEAARPGDGARSAQ **ESGNWRSHRAAVGCSLSNGGAE*VAERPGCAM STHYY*WPFGGPCPNRRGRCTGPRQGLGASRLP QCSCSGPRERRDPSPLGCPSRASSVWVLWSMLH SFYCSHPFL*WAGF*VINVNCLWVKKFLINTYYL L

Frame 1

EVSRKETAAQQPVGRRGGASGAGGGRRGTPRPR AGAGPGFQVSSGGCRLSKMRRFLRPGHDPVRER LKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAI GTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLL PGQCQLVTLLDDNSLHLWSLKVKGGASELQEDE SFTLRGPPGAAPSATQITVVLPHSSCELLYLGTE SGNVFVVQLPAFRALEDRTISSDAVLQRLPEEA RHRRVFEMVEALQEHPRDPNQILIGYSRGLVVI WDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCH SDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKA ITRILWLTTRQGLPFTIFQGGMPRASYGDRHCI SVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDD PYALVVLAEEELVVIDLQTAGWPPVQLPYLASL HCSAITCSHHVSNIPLKLWERIIAAGSRQNAHF STMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRF WDASGVCLRLLYKLSTVRVFLTDTDPNENFSAQ GEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKY SGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADL LQDQEGYRWKGHERLAARSGPVRFEPGFQPFVL VQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFD HQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAK AERPGLQNMELAPVQRKIEARSAEDSFTGFVRT LYFADTYLKDSSRHCPSLWAGTNGGTIYAFSLRV PPAERRMDEPVRAEQAKEIQLMHRAPVVGILVL DGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVS EEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVA HFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLK PQVRYSCIRREDVSGIASCVFTKYGQGFYLISP SEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGA GPKKAPSRARNSGTQSDGEEKQPGLVMERALLS DERAATGVHIEPPWGAASAMAEQSEWLSVQAAR *AHTTTDGLSGVPAPTGEAGAQGPARGWGHPGFH NAAALGLGRGETPVPWAALPGPRLSGSFGQCCT VFIAPIPFCSGLGFKL*MLTASG*KSF**TPIT S*

Frame 2

R*AGRRRPPSSPWAGAAERAGPAAGAEGRRGLG RGLARGSRSPVGAAD*AK*GGS*GQGMTLCGRG SSGTCSSLTRRWSMASRTSPAPSATARPCASWP SAPVLEPSSSTEPQAWSSWGCTRRTTL*RRSTSC PASASWSPCWMTTACTFGA*RSRAGHRSCRRMR ASHCVDPQGLPPVPHRSPWSCHIPPASCSTWAP RVATCLWCSCQLFVRWRTGPSARTRCCSGCQRRP ATGVCSRWWRHCRSTLETPTRS*SATAEASLSS GTYRAAACSTTSSAASNWRTSGGSGTAACSSAV TLTAATASGPCPAKPSNQSPSAASCLTVPFLAKR LPESSG*PLGRGCPSPSSRVACHGPATGTATAS Q*STMASRRPSTSPPVSSASLSSQRQTLQPPLT TPMPWWCWLRRSWW*LTCRQQAGHRSSCPTWLLC TVPPSPALTTSPTSR*SCGSGSLPPAAGRTHTS PPWSGQLMVAPA*PQPHPRGTCCSQGTRTARCG SGMPRVSACGCSTNSALCACSSPTRTPTRTSVPR ARTSGPHSARWAPLTPTVMTPGWASRRSSSAST AATWLWQARQGRCWYWN*MTRQRSRLWSRWRPT CCRTKRATAGRGTSAWQPAQGPCALSLAFSPSCW CSVSPRLWSPPWPCTLSGGSWPSAPAMALASLT TSSGGRSLLSAHCTPVTSWPWRAHSPASSPSRS PCVSHSAGCVGAGCPAGSGTRLAPQERHRRGVPR LSGQASRTWSWRLCSARSRLARQRTPSQASSGP CTLLTPT*RTAPGTAPRCGLAPMGAPSMPSPCV CLPPSGEWMSLCGQSRPRRSS*CTGRRWWASWCS TDTAYPFPSPSKWPMICRRALTCREATSCSSYQ RSSSRCSRCPR*VPS*S*S*RPWRAQECGGSAW PTSAVVEPRTTGSTTWQSLPTWATSRWSRCPCSS PRCATAASAGRTSVASPPASSPNMAKAST*SHP RSLSASLSPPSGWWSPGVWWIQQKPRTTALVTV RAPRRPRAEPGTQGLRVMARRSSPAW*WSALCSV MRERQLAFTSSRRGVQPQQWRSRVSG*ASRLRD EHTLLLMAFRGSLPQPERPVHRAPPGAGGIPAS TMQLLWASGEERPQSPGLPFPGLVCLGPLVNVAQ FLLLPSLFVVGWVLSYKC*LPLGEKVFNKHLLP L

Sequence NM_001031803

GGAGGTGAGCAGGAAGGAGACGGCCGCCCAGCAGCCCGTGGGCAGGCGCGGCGGAGCGAGCGGGGCCGGCGGCGGGCGCCGAGGGACGCCGAGGCCTCGG GCGGGGGCTGGCCCGGGGTTCCAGGTCTCCAGTGGGGGCTGCAGACTAAGCAAAATGAGGCGGTTCCTGAGGCCAGGGCATGACCCTGTGCGGGAGAGGC TCAAGCGGGACCTGTTCCAGTTTAACAAGACGGTGGAGCATGGCTTCCCGCACCAGCCCAGCGCCCTCGGCTACAGCCCGTCCCTGCGCATCCTGGCCAT CGGCACCCGTTCTGGAGCCATCAAGCTCTACGGAGCCCCAGGCGTGGAGTTCATGGGGCTGCACCAGGAGAACAACGCTGTGACGCAGATCCACCTCCTG CCCGGCCAGTGCCAGCTGGTCACCCTGCTGGATGACAACAGCCTGCACCTTTGGAGCCTGAAGGTCAAGGGCGGGGCATCGGAGCTGCAGGAGGATGAGA GCTTCACACTGCGTGGACCCCCAGGGGCTGCCCCCAGTGCCACACAGATCACCGTGGTCCTGCCACATTCCTCCTGCGAGCTGCTCTACCTGGGCACCGA GAGTGGCAACGTGTTTGTGGTGCAGCTGCCAGCTTTTCGTGCGCTGGAGGACCGGACCATCAGCTCGGACGCGGTGCTGCAGCGGTTGCCAGAGGAGGCC CGCCACCGGCGTGTGTTCGAGATGGTGGAGGCACTGCAGGAGCACCCTCGAGACCCCAACCAGATCCTGATCGGCTACAGCCGAGGCCTCGTTGTCATCT GGGACCTACAGGGCAGCCGCGTGCTCTACCACTTCCTCAGCAGCCAGCAACTGGAGAACATCTGGTGGCAGCGGGACGGCCGCCTGCTCGTCAGCTGTCA CTCTGACGGCAGCTACTGCCAGTGGCCCGTGTCCAGCGAAGCCCAGCAACCAGAGCCCCTCCGCAGCCTCGTGCCTTACGGTCCCTTTCCTTGCAAAGCG ATTACCAGAATCCTCTGGCTGACCACTAGGCAGGGGTTGCCCTTCACCATCTTCCAGGGTGGCATGCCACGGGCCAGCTACGGGGACCGCCACTGCATCT CAGTGATCCACGATGGCCAGCAGACGGCCTTCGACTTCACCTCCCGTGTCATCGGCTTCACTGTCCTCACAGAGGCAGACCCTGCAGCCACCTTTGACGA CCCCTATGCCCTGGTGGTGCTGGCTGAGGAGGAGCTGGTGGTGATTGACCTGCAGACAGCAGGCTGGCCACCGGTCCAGCTGCCCTACCTGGCTTCTCTG CACTGTTCCGCCATCACCTGCTCTCACCACGTCTCCAACATCCCGCTGAAGCTGTGGGAGCGGATCATTGCCGCCGGCAGCCGGCAGAACGCACACTTCT CCACCATGGAGTGGCCAATTGATGGTGGCACCAGCCTGACCCCAGCCCCACCCCAGAGGGACCTGCTGCTCACAGGGCACGAGGACGGCACGGTGCGGTT CTGGGATGCCTCGGGTGTCTGCCTGCGGCTGCTCTACAAACTCAGCACTGTGCGCGTGTTCCTCACCGACACGGACCCCAACGAGAACTTCAGTGCCCAG GGCGAGGACGAGTGGCCCCCACTCCGCAAGGTGGGCTCCTTTGACCCCTACAGTGATGACCCCCGGCTGGGCATCCAGAAGATCTTCCTCTGCAAGTACA GCGGCTACCTGGCTGTGGCAGGCACGGCAGGGCAGGTGCTGGTACTGGAACTGAATGACGAGGCAGCGGAGCAGGCTGTGGAGCAGGTGGAGGCCGACCT GCTGCAGGACCAAGAGGGCTACCGCTGGAAGGGGCACGAGCGCCTGGCAGCCCGCTCAGGGCCCGTGCGCTTTGAGCCTGGCTTTCAGCCCTTCGTGTTG GTGCAGTGTCAGCCCCCGGCTGTGGTCACCTCCTTGGCCCTGCACTCTGAGTGGCGGCTCGTGGCCTTCGGCACCAGCCATGGCTTTGGCCTCTTTGACC ACCAGCAGCGGCGGCAGGTCTTTGTTAAGTGCACACTGCACCCCAGTGACCAGCTGGCCTTGGAGGGCCCACTCTCCCGCGTCAAGTCCCTCAAGAAGTC CTTGCGTCAGTCATTCCGCCGGATGCGTCGGAGCCGGGTGTCCAGCCGGAAGCGGCACCCGGCTGGCCCCCCAGGAGAGGCACAGGAGGGGAGTGCCAAG GCTGAGCGGCCAGGCCTCCAGAACATGGAGCTGGCGCCTGTGCAGCGCAAGATCGAGGCTCGCTCGGCAGAGGACTCCTTCACAGGCTTCGTCCGGACCC TGTACTTTGCTGACACCTACCTGAAGGACAGCTCCCGGCACTGCCCCTCGCTGTGGGCTGGCACCAATGGGGGCACCATCTATGCCTTCTCCCTGCGTGT GCCTCCCGCCGAGCGGAGAATGGATGAGCCTGTGCGGGCAGAGCAGGCCAAGGAGATCCAGCTGATGCACCGGGCGCCGGTGGTGGGCATCCTGGTGCTC GACGGACACAGCGTACCCCTTCCCGAGCCCCTCGAAGTGGCCCATGATCTGTCGAAGAGCCCTGACATGCAGGGAAGCCACCAGCTGCTCGTCGTATCAG AGGAGCAGTTCAAGGTGTTCACGCTGCCCAAGGTGAGTGCCAAGCTGAAGTTGAAGCTGACGGCCCTGGAGGGCTCAAGAGTGCGGCGGGTCAGCGTGGC CCACTTCGGCAGTCGTCGAGCCGAGGACTACGGGGAGCACCACCTGGCAGTCCTTACCAACCTGGGCGACATCCAGGTGGTCTCGCTGCCCCTGCTCAAG CCCCAGGTGCGCTACAGCTGCATCCGCCGGGAGGACGTCAGTGGCATCGCCTCCTGCGTCTTCACCAAATATGGCCAAGGCTTCTACCTGATCTCACCCT CGGAGTTTGAGCGCTTCTCTCTCTCCACCAAGTGGCTGGTGGAGCCCCGGTGTCTGGTGGATTCAGCAGAAACCAAGAACCACCGCCCTGGTAACGGTGC GGGCCCCAAGAAGGCCCCGAGCCGAGCCAGGAACTCAGGGACTCAGAGTGATGGCGAGGAGAAGCAGCCCGGCCTGGTGATGGAGCGCGCTCTGCTCAGT GATGAGAGAGTCCTGAAGGAAATCCAGAGCACACTGGAGGGAGACCGCGGGAGCGGCAACTGGCGTTCACATCGAGCCGCCGTGGGGTGCAGCCTCAGCA ATGGCGGAGCAGAGTGAGTGGCTGAGCGTCCAGGCTGCGCGATGAGCACACACTACTACTGATGGCCTTTCGGGGGTCCCTGCCCCAACCGGAGAGGCCG GTGCACAGGGCCCCGCCAGGGGCTGGGGGCATCCCGGCTTCCACAATGCAGCTGCTCTGGGCCTCGGGAGAGGAGAGACCCCAGTCCCCTGGGCTGCCCT TCCCGGGCCTCGTCTGTCTGGGTCCTTTGGTCAATGTTGCACAGTTTTTATTGCTCCCATCCCTTTTTGTAGTGGGCTGGGTTTTAAGTTATAAATGTTA ACTGCCTCTGGGTGAAAAAGTTTTTAATAAACACCTATTACCTCTTGA

refseq_LLGL2.F1 (forward primer)
refseq_LLGL2.R1 (reverse primer)
Single exon skipping

Frame 0

GGEQEGDGRPAARGQARRSERGRRRAPRDAEAS GGGWPGVPGLQWGLQTKQNEAVPEARA*PCAGEA QAGPVPV*QDGGAWLPAPAQRPRLQPVPAHPGH RHPFWSHQALRSPRRGVHGAAPGEQRCDADPPP ARPVPAGHPAG*QQPAPLEPEGQGRGIGAAGG*E LHTAWTPRGCPQCHTDHRGPATFLLRAALPGHR EWQRVCGAAASFSCAGGPDHQLGRGAAAVARGG PPPACVRDGGGTAGAPSRPQPDPDRLQPRPRCHL GPTGQPRALPLPQQPATGEHLVAAGRPPARQLS L*RQLLPVARVQRSPATRAPPQPRALRSLSLQS DYQNPLADH*AGVALHHLPGWHATGQLRGPPLHL SDPRWPADGLRLHLPCHRLHCPHRGRPCSHL*R PLCPGGAG*GGAGGD*PADSRLATGPAALPGFS ALFRHHLLSPRLQHPAEAVGADHCRRQPAERTLL HHGVAN*WWHQPDPSPTPEGPAAHRARGRHGAV LGCLGCLPAAALQTQHCARVPHRHGPQRELQCP GRGRVAPTPQGGLL*PLQ**PPAGHPEDLPLQVQ RLPGCGRHGRAGAGTGTE*RGSGAGCGAGGGRP AAGPRGLPLEGARAPGSPLRARAL*AWLSALRV GAVSAPGCGHLLGPAL*VAARGLRHQPWLWPL*P PAAAAGLC*VHTAPQ*PAGLGGPTLPRQVPQEV LASVIPPDASEPGVQPEAAPGWPPRRGTGGECQ G*AARPPEHGAGACAAQDRGSLGRGLLHRLRPDP VLC*HLPEGQLPALPLAVGWHQWGHHLCLLPAC ASRRAENG*ACAGRAGQGDPADAPGAGGGHPGA RRTQRTPSRAPRSGP*SVEEP*HAGKPPAARRIR GAVQGVHAAQGECQAEVEADGPGGLKSAAGQRG PLRQSSSRGLRGAPPGSPYQPGRHPGGLAAPAQ APGALQLHPPGGRQWHRLLRLHQIWPRLLPDLTL GV*ALLSLHQVAGGAPVSGGFSRNQEPPPW*RC GPQEGPEPSQELRDSE*WRGEAARPGDGARSAQ **ESPEGNPEHTGGRPRERQLAFTSSRRGVQPQQ WRSRVSG*ASRLRDEHTLLLMAFRGSLPQPERP VHRAPPGAGGIPASTMQLLWASGEERPQSPGLP FPGLVCLGPLVNVAQFLLLPSLFVVGWVLSYKC* LPLGEKVFNKHLLPL

Frame 1

EVSRKETAAQQPVGRRGGASGAGGGRRGTPRPR AGAGPGFQVSSGGCRLSKMRRFLRPGHDPVRER LKRDLFQFNKTVEHGFPHQPSALGYSPSLRILAI GTRSGAIKLYGAPGVEFMGLHQENNAVTQIHLL PGQCQLVTLLDDNSLHLWSLKVKGGASELQEDE SFTLRGPPGAAPSATQITVVLPHSSCELLYLGTE SGNVFVVQLPAFRALEDRTISSDAVLQRLPEEA RHRRVFEMVEALQEHPRDPNQILIGYSRGLVVI WDLQGSRVLYHFLSSQQLENIWWQRDGRLLVSCH SDGSYCQWPVSSEAQQPEPLRSLVPYGPFPCKA ITRILWLTTRQGLPFTIFQGGMPRASYGDRHCI SVIHDGQQTAFDFTSRVIGFTVLTEADPAATFDD PYALVVLAEEELVVIDLQTAGWPPVQLPYLASL HCSAITCSHHVSNIPLKLWERIIAAGSRQNAHF STMEWPIDGGTSLTPAPPQRDLLLTGHEDGTVRF WDASGVCLRLLYKLSTVRVFLTDTDPNENFSAQ GEDEWPPLRKVGSFDPYSDDPRLGIQKIFLCKY SGYLAVAGTAGQVLVLELNDEAAEQAVEQVEADL LQDQEGYRWKGHERLAARSGPVRFEPGFQPFVL VQCQPPAVVTSLALHSEWRLVAFGTSHGFGLFD HQQRRQVFVKCTLHPSDQLALEGPLSRVKSLKKS LRQSFRRMRRSRVSSRKRHPAGPPGEAQEGSAK AERPGLQNMELAPVQRKIEARSAEDSFTGFVRT LYFADTYLKDSSRHCPSLWAGTNGGTIYAFSLRV PPAERRMDEPVRAEQAKEIQLMHRAPVVGILVL DGHSVPLPEPLEVAHDLSKSPDMQGSHQLLVVS EEQFKVFTLPKVSAKLKLKLTALEGSRVRRVSVA HFGSRRAEDYGEHHLAVLTNLGDIQVVSLPLLK PQVRYSCIRREDVSGIASCVFTKYGQGFYLISP SEFERFSLSTKWLVEPRCLVDSAETKNHRPGNGA GPKKAPSRARNSGTQSDGEEKQPGLVMERALLS DERVLKEIQSTLEGDRGSGNWRSHRAAVGCSLS NGGAE*VAERPGCAMSTHYY*WPFGGPCPNRRGR CTGPRQGLGASRLPQCSCSGPRERRDPSPLGCP SRASSVWVLWSMLHSFYCSHPFL*WAGF*VINV NCLWVKKFLINTYYLL

Frame 2

R*AGRRRPPSSPWAGAAERAGPAAGAEGRRGLG RGLARGSRSPVGAAD*AK*GGS*GQGMTLCGRG SSGTCSSLTRRWSMASRTSPAPSATARPCASWP SAPVLEPSSSTEPQAWSSWGCTRRTTL*RRSTSC PASASWSPCWMTTACTFGA*RSRAGHRSCRRMR ASHCVDPQGLPPVPHRSPWSCHIPPASCSTWAP RVATCLWCSCQLFVRWRTGPSARTRCCSGCQRRP ATGVCSRWWRHCRSTLETPTRS*SATAEASLSS GTYRAAACSTTSSAASNWRTSGGSGTAACSSAV TLTAATASGPCPAKPSNQSPSAASCLTVPFLAKR LPESSG*PLGRGCPSPSSRVACHGPATGTATAS Q*STMASRRPSTSPPVSSASLSSQRQTLQPPLT TPMPWWCWLRRSWW*LTCRQQAGHRSSCPTWLLC TVPPSPALTTSPTSR*SCGSGSLPPAAGRTHTS PPWSGQLMVAPA*PQPHPRGTCCSQGTRTARCG SGMPRVSACGCSTNSALCACSSPTRTPTRTSVPR ARTSGPHSARWAPLTPTVMTPGWASRRSSSAST AATWLWQARQGRCWYWN*MTRQRSRLWSRWRPT CCRTKRATAGRGTSAWQPAQGPCALSLAFSPSCW CSVSPRLWSPPWPCTLSGGSWPSAPAMALASLT TSSGGRSLLSAHCTPVTSWPWRAHSPASSPSRS PCVSHSAGCVGAGCPAGSGTRLAPQERHRRGVPR LSGQASRTWSWRLCSARSRLARQRTPSQASSGP CTLLTPT*RTAPGTAPRCGLAPMGAPSMPSPCV CLPPSGEWMSLCGQSRPRRSS*CTGRRWWASWCS TDTAYPFPSPSKWPMICRRALTCREATSCSSYQ RSSSRCSRCPR*VPS*S*S*RPWRAQECGGSAW PTSAVVEPRTTGSTTWQSLPTWATSRWSRCPCSS PRCATAASAGRTSVASPPASSPNMAKAST*SHP RSLSASLSPPSGWWSPGVWWIQQKPRTTALVTV RAPRRPRAEPGTQGLRVMARRSSPAW*WSALCSV MRES*RKSRAHWRETAGAATGVHIEPPWGAASA MAEQSEWLSVQAAR*AHTTTDGLSGVPAPTGEA GAQGPARGWGHPGFHNAAALGLGRGETPVPWAAL PGPRLSGSFGQCCTVFIAPIPFCSGLGFKL*ML TASG*KSF**TPITS*